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The TPP of order "r"-1 is an "r"-partite hypergraph: its vertices can be partitioned into "r" parts such that each hyperedge contains exactly one vertex of each part. For example, in the TPP of order 2, the 3 parts are {1,6}, {2,5} and {3,4}. In general, each of the "r" parts contains "r"-1 vertices.
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Detailed understanding of the mechanism behind this post translational silencing pathway was established in 2001 by Thomas Tuschl. It was discovered that the double stranded RNA gets processed into a shorter 25 nucleotides long fragment which is then modified into a short hairpin like structure by Drosha complex. The molecule is then diced by dicer enzymes into a functional double stranded RNA (dsRNA). These are then loaded onto the RISC complex which then finds and cleaves the targeted mRNA of interest in the cytoplasm.
https://en.wikipedia.org/wiki?curid=70197321
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Chair: Alice Soldà (Italy); Secretary: Torsten John (Germany); Communication team leader: Kseniia Otvagina (Russia); Membership team leader: Jelena Lazić (Serbia); Networks team leader: Victor Mougel (France); Science team leader: Hanna Makowska (Poland); Advisor: Fernando Gomollón-Bel (Spain)
https://en.wikipedia.org/wiki?curid=41305472
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Metadata in BisQue can take many forms: text, objects of interest, user annotations or another web-based file (e.g. associated publication in PDF). Textual and graphical markup viewing and editing is available in the web 5D image viewer. The viewer is used for image and object browsing, ground-truth acquisition and statistical summaries of biological objects. Additionally, it allows for various visualization options such as channel mapping, image enhancement, projections and rotations. The most recent image viewer is able to present volumetric imagery in 3D without browser plug-ins by utilizing modern browsers' WebGL capabilities.
https://en.wikipedia.org/wiki?curid=47489445
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Valencia's win was Mexico's sole victory in the archery competitions of the 2019 Pan American Games and the nation's 37th gold medal of the Games, its highest Pan American tally away from home.
https://en.wikipedia.org/wiki?curid=61470589
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Other authors use different growth conditions and different proof conditions. The first proof of it was due to Morrey in his paper, but he required additional assumptions.
https://en.wikipedia.org/wiki?curid=71193979
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Arm TechCon 2017, with the tag line "Tackling the challenges of securing a trillion connected devices", was held from October 24 to October 26, 2017 at the Santa Clara Convention Center, California.
https://en.wikipedia.org/wiki?curid=71722793
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The family group taxon was established by Needham (1903) as subfamily Stenophlebinae (sic) of the extinct damsel-dragonfly family Heterophlebiidae. It was emended and elevated to family rank Stenophlebiidae by Handlirsch (1906). "Stenophlebia" Hagen, 1866 is the type genus of this family.
https://en.wikipedia.org/wiki?curid=36766650
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The first recipient of the MacLean Center Prize was Dr. John Wennberg, the Peggy Y. Thomson Professor Emeritus for the Evaluative Clinical Sciences at Dartmouth Medical School.
https://en.wikipedia.org/wiki?curid=32336815
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In 1984 the National Research Council of Canada established the Associate Committee for the Occupational Applications of Ergonomics. Drawing members from government agencies, the universities, industry and commerce, and trade unions, the Associate Committee was mandated to promote the application of ergonomics to industry on the assumption that this either was not, or was inadequately, being done already. Committee members set out across Canada to bring the message to workers, managers and employers, with diverse results. In one city two hundred persons attended a one-day workshop sponsored by the Committee while in another barely a dozen turned up. In these workshops the speakers endeavoured to stress the broad scope of ergonomics, pointing out that ergonomics was pertinent not only to occupational health and safety but also to efficiency and effectiveness.
https://en.wikipedia.org/wiki?curid=23196738
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Gambia lacked sufficient staff and equipment to treat its population of 1.5 million to proper surgical care. The program was focused on training nurses in child and maternal health care, with the help of an emergency obstetrical flying squad. In the first two months of implementation 27 lives were saved.
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In some experiments, the surface collector was coated with an alginate layer with negative charge for simulating the real conditioning film in natural system.
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On May 14, Indiana played second seeded Pittsburgh from the ACC in the College Cup semifinals, which was the second match of a doubleheader at WakeMed Soccer Park. In front of a crowd of 2,667, Indiana's Herbert Endeley scored a goal in the 79th minute to lift the Hoosiers past the Panthers and into the National Championship game by a score of 1–0
https://en.wikipedia.org/wiki?curid=66373067
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The C4ISR experiment provided input to the FCS Analysis of Alternatives and the Operational and Objective (O&O) analysis to support the FCS Milestone B decision. The experiment was conducted in a human-in-the-loop, simulation supported, secure environment. The experiment focused on the issues of battle command and how it affected measures of force effectiveness.
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After accessing the STARNET Homepage, the user is introduced to the following nine scientific or thematic nodes:
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The event is open to children of all ages. Children can participate in simulated archaeological excavations under the guidance of staff from Mississippi State's Cobb Institute of Archaeology. Children can learn archaeological knowledge in the process, including the tools, techniques and items found during the excavation process.
https://en.wikipedia.org/wiki?curid=60757808
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A visualization from the Bolshoi Cosmological Simulation was narrated in the National Geographic TV special "Inside the Milky Way". UC-HiPACC provided footage from the Bolshoi Simulation to the Icelandic performer Björk for her musical number “Dark Matter” for her Biophilia concert.
https://en.wikipedia.org/wiki?curid=41580518
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has degenerate singularity at some "p". A function has degenerate singularity if both the Jacobian matrix of first order partial derivatives and the Hessian matrix of second order partial derivatives have zero determinant.
https://en.wikipedia.org/wiki?curid=18906055
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Taking into account the properties of the Heaviside step function and Dirac delta function, this equation simply leads to
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These are complex and specialized cells. However, the improved understanding of cellular evolution achieved over the last several years has revealed that even the most sophisticated and unique properties of nerve cells represent an adaptation of basic functions observed in all eukaryotic cells, including unicellular organisms. Thus, cellular neurobiology has become an important chapter of cell biology. Studies of neurons greatly capitalize on progress in fundamental cell biology. Conversely, research on specialized features of neurons is producing major fall-outs in other areas of biology. Projects of cellular neurobiology in the department focus on mechanisms in membrane traffic at the synapse, on the development and maintenance of cell polarity and on the mechanisms responsible for the heterogeneous distribution of organelles and macromolecules within the neuronal cytoplasm. Formation and plasticity of synapses are also investigated. In the tradition of the department, questions in these fields are approached in a multidisciplinary fashion using genetics, protein and lipid biochemistry, molecular biology and state of the art light and electron microscopy imaging techniques. Experimental systems include mouse models, cultured neurons, large model synapses, isolated synaptic preparations and cell free systems. Special emphasis is placed on interfaces between this basic research and disease.
https://en.wikipedia.org/wiki?curid=5463771
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A particular miRNA, MiR-182, has been found to impact MITF and FOXO3, which are tumor suppressor genes. MiR-182 is a member of a miRNA cluster in a chromosomal locus that is most often amplified in melanoma (Segura "et al." 2009). It is frequently up-regulated in human melanoma tissue samples and cell lines, and this up-regulation causes its ectopic expression, which stimulates migration of melanoma cells, both in vitro and in vivo. The down-regulation of this miRNA triggers apoptosis. Over-expression of miR-182 in malignancy has been shown to negatively impact these tumor suppressor genes by directly repressing them. The repression of these genes allows miRNA to promote the spread and migration of melanoma cells, not taking into account the properties necessary for metastasis to occur.
https://en.wikipedia.org/wiki?curid=42683705
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The substrate can be heated during deposition by either passing direct current through the sample for semiconductors or by driving current through a separate heating foil underneath the substrate for insulating oxides.
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It is also worth noting the role of members of the Organizing Committee and pillars of the Operations Research and Management Science group at the Poznań University of Technology: Professors Jacek Błażewicz, Roman Słowiński and Jan Węglarz, in the support and organization process of the EURO 2016 conference that stimulated communication and cooperation among the most important European operational researchers.
https://en.wikipedia.org/wiki?curid=54423769
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The AMS 2000 family of storage systems provides software wizards and web-based tools for configuration, management and maintenance. Flexible sparing of disk drives eliminates the need to
https://en.wikipedia.org/wiki?curid=30133886
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The IBA grants fellowship awards to outstanding scholars who have made significant contributions to the field of mathematical biology.
https://en.wikipedia.org/wiki?curid=63192046
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Each edge in a TPP intersects every other edge. Therefore, its maximum matching size is 1:formula_1.On the other hand, covering all edges of the TPP requires all "r"-1 vertices of one of the parts. Therefore, its minimum vertex-cover size is "r"-1:formula_2.Therefore, the TPP is an extremal hypergraph for Ryser's conjecture.
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It wasn’t until 1989 that the imprinting genes were discovered and the genome imprinting was established. The first two genomic imprinting genes were paternally expressed "Igf2r" and "H19". These were both discovered independently in mice and were localized to chromosome 7. "H19" is peculiar as it functions as a lncRNA but undergoes modifications similar to that of pre-mRNA processing such as splicing, 3’ polyadenylation and is transcribed by RNA polymerase II. This lncRNA plays a significant role in mice embryonic development and can be lethal if expressed during prenatal stages. More lncRNAs have been discovered in eukaryotes overtime. One such discovery that allowed for better understanding between "H19" functions was a lncRNA called XIST (X inactive-specific transcript).
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Key achievements: The webpage "Chemistry across Europe" providing the basic information about chemistry in the academic and industrial field across Europe and the EYCN YouTube channel were established. The 2nd European Young Chemists' Meeting (EYCheM) was organized in collaboration with the JCF Bremen.
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Biological image sharing has often been difficult due to proprietary formats. In BisQue, sharing images, metadata and analysis results can be performed through the web. The system contains an export facility that allows conversions of image formats, application of a variety of image-processing operations and export of textual or graphical annotations as XML, CSV or to Google Docs.
https://en.wikipedia.org/wiki?curid=47489445
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Arm TechCon 2018, with the tag line "Arm to reveal details on the 5G, cloud and IoT infrastructures for a trillion connected devices", was held from October 16 to October 18, 2018 at the San Jose Convention Center, California.
https://en.wikipedia.org/wiki?curid=71722793
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The species "Sinostenophlebia zhanjiakouensis" was originally assigned to the family Stenophlebiidae; however, the position and status of this species is very uncertain due to the poor preservation and insufficient original description. Zheng "et al." (2016) transferred this species to the family Aeschnidiidae, and considered the genus "Sinostenophlebia" to be a likely junior synonym of the genus "Leptaeschnidium".
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The most recent recipient of the MacLean Center Prize, recognized in November 2012, is " Dr. Peter Singer ". A former MacLean Center Fellow, Dr. Singer has dedicated much of his career to the ethics of global health.
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The Associate Committee sponsored surveys and seminars implicating government occupational health and safety agencies, ergonomics teachers, trade unions and ACE and successfully raised awareness of the issues. It tried equally to implicate industrialists and engineers but with mixed results. The Committee succeeded in co-sponsoring (with ACE) the appointment of an industry technical advisor by the NRC Industrial Research Assistance Program but failed to persuade the Natural Sciences and Engineering Research Council of Canada to establish a grants committee for ergonomics.
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A mycobacterial skin disease occurring primarily in children under 15 years old prompted the Buruli Ulcer program, which provided education on the treatment of the ulcers that result from the skin disease. Equipment for safe surgery, as well as refurbished health facilities were ongoing challenges.
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It was concluded that bacterial deposition mainly occurred in a secondary energy minimum by using DLVO theory. DLVO calculation predicted an energy barrier of 140kT at 31.6 mM ionic strength to over 2000kT at 1mM ionic strength. This data was not in agreement with the experimental data, which showed increasing deposition with increasing ionic strength. Therefore, the deposit could occur at secondary minimum having the energy from 0.09kT to 8.1kT at 1mM and 31.6 mM ionic strength, respectively. The conclusion was further proven by the partial release of deposited bacteria when the ionic strength decreased. Because the amount of released bacteria was less than 100%, it was suggested that bacteria could deposit at the primary minimum due to the heterogeneity of the surface collector or bacterial surface. This fact was not covered in classical DLVO theory.
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The Omni-Fusion experiments built on the concepts of Battle Command Re-Engineering and C4ISR to refine designs and concepts for the Future Combat Systems Program. The application of widely distributed simulation to classified experimentation was highly developed during these exercises.
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Clicking on any of the nodes will introduce the user to the Homepage of that node from which you can mount your searches. The Node Homepage also displays the Topic Area Descriptions and Resources of the node, as well as Organization Type Descriptions and Resources.
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The research results of the Cobb Institute will be presented in The Lois Dowdle Cobb Museum of Archaeology. This museum not only serves as a display platform for the Cobb Institute, but also provides a lot of help for the research work of the Cobb Institute. Relevant exhibition activities will be held regularly to promote and achieve teaching results. The Lois Dowdle Cobb Museum of Archaeology mainly displays artifacts related to the Indians of the southeastern United States, and the cultural relics related to the Middle East and the Mediterranean.
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To discover if the Jacobian matrix has zero determinant, differentiating the equation "x - p = Z + ΔA" is needed. Let "X" be a tangent vector to "M", and differentiate in that direction:
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Discretization of this equations can be carried out with the MLS approximation, for the local domain formula_47, in terms of the nodal unknowns formula_55, thus leading to the system of linear algebraic equations that can be written as
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In a fairly recent experiment done by Penna "et al." on miRNA-214, it was shown that the miRNA regulates the expression of a panel of 11 target genes, including TFAP2C and ITGA3, and contributes to melanoma tumor progression by suppressing those genes. In this experiment, these genes, known to contain one or more binding sites of the miRNA, were obtained and their three prime untranslated regions (3'UTRs) cloned into a vector. Luciferase assays were then performed in MA-2 and/or MC-1 cells transfected with the miRNA. It was reported that luciferase expression, which was driven by the 3'UTRs of integrin alpha 3 (ITGA3) or transcription factor AP-2 gamma (TFAP2C), was repressed significantly. The team then tried to assess whether the luciferase expression regulation seen in the ITGA3 and TFAP2C genes depended on the binding between the miRNA and the complementary sequence that was present on the 3'UTRs of either gene. A four nucleotide deletion or three point mutations were respectively inserted in the ITGA3 or TFAP2C 3'UTRs, and the 3'UTR alterations entirely abrogated the effect of the miRNA over-expression on luciferase expression in the MA-2 and MC-1 cells. This observation indicated the direct regulation of miRNA-214 on the 3'UTR binding sites of the ITGA3 and TFAP2C genes.
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The capabilities of the system were first tested by growing arrays of 10-30 nm wide metallic nanowires on two types of vicinal substrates, step-bunched Si(111) and α-AlO(0001). Deposition of Au and Ag onto these substrates yields arrays of wires with a width and height of 15 nm and 2 nm, and separated by approximately 30 nm.
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The Society awards medals for outstanding achievements in the field of operational and systems research. Special awards for book publications and for young researchers are also planned.
https://en.wikipedia.org/wiki?curid=54423769
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The AMS 2100 has the ability to scale capacity to 469TB and delivers performance of up to 400K IOPS. This storage system has 16 concurrent disk I/O paths providing up to 4800MB/s of total system bandwidth. It has connectivity for up to 1024 virtual server ports and supports the intermix high performance SAS drives and cost optimized SATA drives in the same system for tiered storage solutions. It can attach to both Fibre Channel and iSCSI storage networks.
https://en.wikipedia.org/wiki?curid=30133886
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The minimum fractional vertex-cover size of the TPP is "r"-1 too: assigning a weight of 1/"r" to each vertex (which is a vertex-cover since each hyperedge contains "r" vertices) yields a fractional cover of size ("r"-"r")/"r"="r"-1.
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The first ncRNA therapeutic drug approved by food and drug administration (FDA) (1998) and the European medicine agency (EMA) (1999) is called Fomivirsen or Vitravene. The target organ is the eye and works against the cytomegalovirus (CMV) retinitis in immunocompromised patients. The drug functions as an antisense oligonucleotide and binds to the complementary sequence of the mRNA that inhibits the replication of human cytomegalovirus. This therapy can also be categorized as Antisense oligonucleotide (ASO) therapy.
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Chair: Fernando Gomollón-Bel (Spain); Secretary: Camille Oger (France); Science team leader: Oana Fronoiu (Romania); Communication team leader: Sarah Newton (UK); Networks team leader: Michael Terzidis (Greece); Membership team leader: Emanuel Ehmki (Austria)
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All services and modules are accessible via standard web access methods (HTTP). This permits a wide variety of tools, from web browsers to custom analysis applications, to interact with BisQue. Most BisQue services are implemented using the RESTful design pattern architecture that exposes resources through URIs. Resources are manipulated by using the common HTTP methods. Among many benefits attributed to RESTful pattern are scalability through web caches and the use of client side state and processing resources. Bisque services exchange data in XML format.
https://en.wikipedia.org/wiki?curid=47489445
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Arm TechCon 2019, with the tag line "Showcasing the New Era of Total Compute", was held from October 8 to October 10, 2019 at the San Jose McEnery Convention Center, California.
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Bechly (2005) could show that the very small species ""Stenophlebia"" "casta" from the Upper Jurassic Solnhofen Plattenkalk of Germany is not related to Stenophlebiidae. It is now classified as "Parastenophlebia casta" in a separate family Parastenophlebiidae that belongs to the extinct damsel-dragonfly suborder Heterophlebioptera.
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Of the institutions that have played a role in developing ergonomics in Canada, the universities are the ones whose contribution has been most ambivalent. Ergonomics has been taught as a university subject for many years, but in a variety of departments ranging from kinesiology, psychology and biological sciences to industrial relations, industrial engineering, systems engineering and other engineering disciplines. This has had the benefit of bringing to the teaching of ergonomics the full range of knowledge and techniques that the subject calls for, but it has led to some disarray. Ergonomics is compelled, in many cases, to occupy the minor role in a department named for and devoted to some other discipline, and what students receive has been shaped accordingly. No Canadian university has a dedicated Department of Ergonomics.
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The GIEESC had been holding courses on disaster management and polytrauma, as well as a workshop for surgical technicians, and the founding of the National Program for Infection Control.
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The presence of divalent electrolytes (Ca) can neutralize the charge surface of bacteria by the binding between Ca and the functional group on the oocyst surface. This resulted in an observable bacterial deposition despite the very high electrostatic repulsive energy from the DLVO prediction.
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The Urban Resolve 2015 was designed to examine Joint Urban Operations (JUO), Military Support for Stabilization, Security, Transition and Reconstruction Operations (SSTRO), and Major Combat Operations (MCO).
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In order to achieve the purpose of promotion and education, the museum will also hold an exhibition on the pottery making process and the meteorite tools. It also includes an exhibition about environmental and fauna research which related to the Europe and the Native Americans in the southeastern United States and some related artifacts.
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where "I" is the identity. This means that formula_31 and formula_32. The last equality says that we have the following equation of differential one-forms formula_33. The Jacobian matrix will have zero determinant if, and only if, formula_34 is degenerate as a one-form, i.e. formula_35 for all tangent vectors "X". Since formula_33 it follows that formula_34 is degenerate if, and only if, formula_38 is degenerate. Since "h" is a non-degenerate two-form it follows that "Z = 0". Notice that since "M" has a non-degenerate second fundamental form it follows that "h" is a non-degenerate two-form. Since "Z = 0" the set of ambient points "x" for which the restricted function formula_27 has a singularity at some "p" is the affine normal line to "M" at "p".
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This formulation states the equilibrium of tractions and body forces, pointwisely defined at collocation points, obviously, it is the pointwise version of the Euler-Cauchy stress principle. This is the equation used in the Generalized-Strain Mesh-Free (GSMF) formulation which, therefore, is free of integration. Since the work theorem is a weighted-residual weak form, it can be easily seen that this integration-free formulation is nothing else other than a weighted-residual weak-form collocation. The weighted-residual weak-form collocation readily overcomes the well-known difficulties posed by the weighted-residual strong-form collocation, regarding accuracy and stability of the solution.
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Further experiment on protein expression was also conducted on these two particular genes, TFAP2C and ITGA3, and it was shown that miRNA-214 over-expression led to a 30-90% protein decrease in ITGA3 and a 40-80% decrease in TFAP2C (Penna et al., 2011). Consistently, proteins were upregulated 20% in the ITGA3 and 40% in the TFAP2C when miRNA-214 was silenced in the MC-1 cell. This suggests that miRNA-214 importantly regulates the expression of the ITGA3 and TFAP2C genes and promotes melanoma tumor progression when overly expressed.
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Since its introduction in 2008, ATLAS has been demonstrated as a simple technique to produce nanowires of a variety of materials down to a width of 15 nm and thickness of 2 nm, on several stepped substrates.
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Among the prizes won by the members of POSRS (PTBOiS) it is worth emphasizing EURO Gold Medal won by Professors: Jacek Błażewicz, Roman Słowiński, and Jan Węglarz, leaders of the Operations Research and Management Science group established within the Faculty of Computing at Poznań University of Technology.
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The AMS 2300 has the ability to scale capacity to 708TB and can deliver performance of up to 400K IOPS. It supports connectivity to 2048 virtual server ports and is able to intermix high performance SAS drives and cost optimized SATA drives in the same system. This system has 16 concurrent disk I/O paths providing up to 4800MB/s of total system bandwidth. It can also attach to either or both Fibre Channel and iSCSI storage networks for storage consolidation.
https://en.wikipedia.org/wiki?curid=30133886
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Its maximum fractional matching size of the is "r"-1 too: assigning a weight of 1/("r-1") to each hyperedge (which is a matching since each vertex is contained in "r"-1 edges) yields a fractional matching of size ("r"-"2r"+1)/("r"-1)="r"-1. Therefore:formula_3.Note that the above fractional matching is perfect, since its size equals the number of vertices in each part of the "r"-partite hypergraph. However, there is no perfect matching, and moreover, the maximum matching size is only 1. This is in contrast to the situation in bipartite graphs, in which a perfect fractional matching implies the existence of a perfect matching.
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There have been many ASO RNA therapeutics that have been approved by FDA and/or EMA over the years, but it wasn’t until 2018 that the EMA approved the drug called Patisiran/Onpattro. The drug uses ds-siRNA as a mechanism of action and is deemed effective against hereditary transthyretin amyloidosis. The mechanism specifically targets the Transthyretin (TTR) mRNA.
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Key achievements: The rules for the election process of the EYCN board and the attendance to the DA were established and the publication of a monthly newsletter was decided.
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For easy integration with existing software, BisQue also provides an API that covers all aspects of resource ingestion, search, analysis, and manipulation. It is currently available for Python and Matlab.
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Arm DevSummit 2020 was held from October 5 to October 9, 2020 as an online-only conference due to the COVID-19 pandemic.
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The set of shared derived characters listed in the description section above demonstrate that Stenophlebiidae is clearly a monophyletic group (clade).
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This lack of cohesion is reflected today in the attitudes of managers, trade unionists, and members of the public in general towards ergonomics. For example, the introduction of information technology into the workplace has led to changes in workplace structure and procedures that call for the application of ergonomics theory and technique. But ergonomics has become associated with the single issue of avoiding repetitive-strain injuries. The topic of man- or (more properly) operator-machine interface has become a hardy perennial at all conferences designed for computer engineers and computer scientists, but it has assumed a life of its own divorced from a more comprehensive ergonomic approach.
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Plans for Uganda involved implementing better care to lower levels of health facilities, and providing training and surgical services to camps in rural areas.
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The motility of bacteria also has a significant effect on the bacterial adhesion. Nonmotile and motile bacteria showed different behavior in deposition experiments. At the same ionic strength, motile bacteria showed greater adhesion to the surface than nonmotile bacteria and motile bacteria can attach to the surface of the collector at high repulsive electrostatic force. It was suggested that the swimming energy of the cells could overcome the repulsive energy or they can adhere to regions of heterogeneity on the surface. The swimming capacity increase with the ionic strength and 100mM is the optimal concentration for the rotation of flagella.
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The RUX06 was a true LVC event, combining manned simulators, a force wraparound generated in constructive simulation with actual vehicles fitted with emulators of future C2 technologies on the ranges at Ft. Knox in real-time; this experiment examined workload and stress of crews of future manned vehicles under varied threat conditions.
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The Professional protection history personnel from this institute are in charge of perform this cultural resource management services, and the main purpose of the service is to help clients who want to develop projects, such as companies and developers, government agencies and citizens, to satisfy the law and provide assistance of the relationship between clients and local, state and federal agencies and tribes.
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To compute the Hessian matrix, consider the differential two-form formula_40. This is the two-form whose matrix representation is the Hessian matrix. It has already been seen that formula_32 and that formula_42 What remains is
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Many genes are altered genetically and epigenetically in cancers, which is one of the reasons cancer is so hard to combat. INK4A and PTEN are two genes that are in both Tables 1 and 2 above, as they are both epigenetically and genetically mutated in melanoma cases. This is not uncommon, as cells need multiple changes to the genome to initiate a change as large as cancer. The epigenetic side of cancer research is growing and uncovering many overlaps like in the cases of INK4A and PTEN, giving a larger, more accurate image of cancer and melanoma. The complexity and variability of cancer epigenetics makes this a growing and important field. Since epigenetic modifications are able to be reversed, this makes them a target for therapeutics and part of the future of cancer combat, and specifically melanoma, due to its deadliness and difficulty to catch. The genes listed above are only the beginning of a long list of available treatment areas that could potentially reverse or prevent melanoma if detected early.
https://en.wikipedia.org/wiki?curid=42683705
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Although ATLAS is a versatile technique, some limitations do exist. The initial growth of the nanowires is nucleated on certain preferential adsorption sites. This can form epitaxial seeds, which grow independently of each other, until they meet, which forms an overall polycrystalline wire. This polycrystallinity can affect the stability of the wire when exposed to air, and can increase the resistance due to its defective nature. It is an ongoing topic of research to increase the quality of nanowires by lattice matching, or increasing initial mobility through heating of the substrate.
https://en.wikipedia.org/wiki?curid=32743838
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The AMS 2500 is capable of scaling capacity to 1,417TB and delivering performance up to 900K IOPS with connectivity for up to 2048 virtual server ports. It has 32 concurrent disk I/O paths providing 9600MB/s of total system bandwidth. This storage system supports intermix of high performance SAS drives and cost optimized SATA drives for tiered storage solutions. It supports connectivity to Fibre Channel and iSCSI storage networks for storage consolidation.
https://en.wikipedia.org/wiki?curid=30133886
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Dual affine planes can be viewed as a point residue of a projective plane, a 1-design, and, more classically, as a tactical configuration.
https://en.wikipedia.org/wiki?curid=64551468
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RNA therapeutic targets are not limited to mature mRNA but have been used to target mRNA at different stages of maturation. One such example is Nusinersen (Spinaraza), it functions as an ASO and targets pre-mRNA before splicing that corresponds to Survival of motor neuron 2 gene (SMN 2). This drug therapy was approved by FDA and EMA in 2016 and 2017 respectively.
https://en.wikipedia.org/wiki?curid=70197321
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Chair: Frédérique Backaert (Belgium); Secretary: Aurora Walshe (UK); Scientific team leader: Vladimir Ene (Romania); External communication team leader: Lisa Phelan (Ireland); Membership team leader: Koert Wijnbergen (The Netherlands); Networks team leader: Anna Stefaniuk-Grams (Poland); Advisor: Cristina Todaşcă (Romania)
https://en.wikipedia.org/wiki?curid=41305472
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BisQue has been used to manage and analyze 23.3 hours (884GB) of high definition video from dives in Bering Sea submarine canyons to evaluate the density of fishes, structure-forming corals and sponges and to document and describe fishing damage. Non-overlapping frames were extracted from each video transect at a constant frequency of 1 frame per 30s. An image processing algorithm developed in Matlab was used to detect laser dots projected onto the seafloor as a scale reference. BisQue's module system allows to wrap this Matlab code into an analysis module that can be parallelized across a compute cluster. In addition, each frame was manually annotated with objects of interest (e.g., fishes, sponges, substrates) and these annotations and other image metadata (e.g., pixel resolution, GPS location) was stored in BisQue's flexible metadata store. The annotations were then used to compute the average density of species and co-habitation behavior in different regions of the canyons, resulting in new insights into this ecosystem.
https://en.wikipedia.org/wiki?curid=47489445
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Arm DevSummit 2021, with the tag line "Where Hardware and Software Join Forces", was held from October 19 to October 21, 2021 as an online-only conference due to the COVID-19 pandemic.
https://en.wikipedia.org/wiki?curid=71722793
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Before the advent of cladistic classification Stenophebiidae was classified within the odonate suborder Anisozyoptera, which was later recognized to be a paraphyletic grade. In modern classifications the taxon Anisozygoptera is therefore either abandoned or restricted to the Recent relict family Epiophlebiidae.
https://en.wikipedia.org/wiki?curid=36766650
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The eventual outcome of this state of affairs remains to be seen. With universities interested more in areas of application (like women's studies, aboriginal studies, environmental studies, management studies) rather than basic disciplines, little relief is likely to come from that area. On the other hand, in 1998, after years of preparation, ACE established the Canadian College for the Certification of Professional Ergonomists/Conseil Canadien de certification des praticiens en ergonomie with a current (2021) membership of more than 260 certified professional ergonomists. Strong professional associations like ACE and CCCPE may make the difference.
https://en.wikipedia.org/wiki?curid=23196738
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Challenges to proper surgical care in Zambia included lack of staff, poor infrastructure, inadequate supplies, and difficulty in accessing health care. A situational analysis was underway.
https://en.wikipedia.org/wiki?curid=20494734
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Despite the electrostatic repulsion energy from DLVO calculation between the bacteria and surface collector, the deposition could occur due to other interactions such as the steric impact of the presence of flagella on the cell environment and the strong hydrophobicity of the cell.
https://en.wikipedia.org/wiki?curid=20631781
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The Counter Insurgency Experiment was a large, multi-site exercise that included most members of the BLCSE. It simulated downtown Baghdad, Iraq, with US and Iraqi soldiers, Iraqi police, armed and unarmed civilians from several groups, like Shia and Sunni, and armed insurgents. It examined how Future Combat Systems technologies work in a dense, urban environment.
https://en.wikipedia.org/wiki?curid=27919032
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On February 27, 2006, the external advisory committee of the Cobb Institute of Archaeology was established, consisting of several outstanding scholars or managers from all over the country.
https://en.wikipedia.org/wiki?curid=60757808
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This is degenerate as a two-form if, and only if, there exists non-zero "X" for which it is zero for all "Y". Since "h" is non-degenerate it must be that formula_47 and formula_48. So the singularity is degenerate if, and only if, the ambient point "x" lies on the affine normal line to "p" and the reciprocal of its distance from "p" is an eigenvalue of "S", i.e. points formula_49 where 1/"t" is an eigenvalue of "S". The affine focal set!
https://en.wikipedia.org/wiki?curid=18906055
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Despite these limitations, ATLAS's results of a 15 nm width is approximately a five-fold reduction in size compared to other shallow-angle techniques.
https://en.wikipedia.org/wiki?curid=32743838
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The AMS 2500DC is designed for operation in DC powered data centers typically found in telco central offices and large or enterprise businesses.
https://en.wikipedia.org/wiki?curid=30133886
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Since they are not pairwise balanced designs (PBDs), they have not been studied extensively from the design-theoretic viewpoint. However, tactical configurations are central topics in geometry, especially finite geometry.
https://en.wikipedia.org/wiki?curid=64551468
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There are some drugs that have been approved by FDA and not by EMA. This can be seen in the case of an ASO type therapeutics called Eteplirsen (Exondys51) which has been approved by FDA in 2016 but not by EMA. It targets pre-mRNA corresponding to Dystrophin (DMD) and works against Duchenne muscular dystrophy.
https://en.wikipedia.org/wiki?curid=70197321
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Key achievement: First participation of the EYCN at the EuCheMS Chemistry Congress (ECC5) in Istanbul, Turkey in 2014.
https://en.wikipedia.org/wiki?curid=41305472
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The BisQue platform is part of the iPlant Cyberinfrastructure (now the CyVerse) to analyze plant-related images in the context of phenotype analysis. BisQue was integrated with iPlant’s authentication, cloud storage, and high-performance grid computing infrastructure and configured with sample data and algorithms designed to assay phenotypes such as directional root-tip growth or comparisons of seed size differences.
https://en.wikipedia.org/wiki?curid=47489445
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Arm DevSummit 2022, with the tag line "Build Your Future on Arm", is an upcoming online technology conference for software developers on October 26 with workshops on November 7 and 9.
https://en.wikipedia.org/wiki?curid=71722793
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Bechly (1996) established a new suborder Stenophlebioptera for Stenophlebiidae and its closest relatives. Stenophlebioptera is closer related to Anisoptera than Epiophlebiidae.
https://en.wikipedia.org/wiki?curid=36766650
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Temporary surgical units in rural health centers have been set up, along with training of doctors there(“WHO Meeting").
https://en.wikipedia.org/wiki?curid=20494734
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composed of a Combined Arms Bn (CAB), one Stryker Infantry Battalion, Force Design Update (FDU) Reconnaissance Squadron, supported by appropriate joint and army enablers against a predominantly dismounted enemy that was embedded in a semi-urban environment. It was one of the first large distributed exercises using OneSAF with classified performance data.
https://en.wikipedia.org/wiki?curid=27919032
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The conditions for joining the board of directors of the Cobb Institute are as follows: Each member of the board of directors shall not serve for more than three years. If the member has already served for a term of three years, a new member will be replaced. The board of directors was established to give guidance and suggestion to the internal management committee of the Cobb Institute, therefore assists the Institute's base and projects to supply opportunities and challenges for the community of university and the public.
https://en.wikipedia.org/wiki?curid=60757808
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The affine focal set is singular if, and only if, there exists non-zero "X" such that formula_52, i.e. if, and only if, "X" is an eigenvector of "S" and the derivative of "t" in that direction is zero. This means that the derivative of an affine principal curvature in its own affine principal direction is zero.
https://en.wikipedia.org/wiki?curid=18906055