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It is capable of scaling capacity up to 472TB and delivering performance up to 900K IOPS with connectivity for up to 2048 virtual server ports. This model supports intermix of high performance SAS drives and cost optimized SATA drives in the same system for tiered storage solutions. It supports connectivity to Fibre Channel and iSCSI storage networks for storage consolidation. This models employs NEBS-3/ETSI compliant, -48V DC power supply for telcos and DC powered data centers.
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According to , the term "tactical configuration" appears to be due to E. H. Moore in 1896. For the history of dual configurations, see Duality (projective geometry)#History.
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There are many additional therapeutics that have been developed and are either in phase I or II of the clinical trials. Current RNA therapeutics in clinical trials range from a variety of target organs and diseases ranging from skin (potential treatment for disease such as keloid) to tumors (squamous cell lung cancer).
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Key achievement: The EYCN was for the first time organized into teams, each with its own leader and delegates as team members.
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As of version 0.5.5, BisQue is released under a modified BSD license that requires proper and visible attribution of the BisQue project if the whole or parts of BisQue are used for either research or commercial purposes.
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The extinct family Prostenophlebiidae is the sister group of Stenophlebiidae within the superfamily Stenophlebioidea. Stenophlebioidea is the sister group of Liassostenophlebiidae within the suborder Stenophlebioptera.
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Various steps had been taken to improve Mongolia’s emergency surgical care: the training of 300 primary health workers at main hospitals and 120 workers at primary health facilities, the translation of necessary WHO tools into Mongolian.
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The Advanced Reconfigurable Research Tool was a virtual simulator developed using OneSAF TestBed as a software base. It was very modular to allow rapid changes to vehicle characteristics, and it could model many vehicle types, like the M1 Abrams, M2 Bradley, Stryker, HMMWV, along with various variants from the Future Combat Systems program. It incorporated an innovative mobility model for the OneSAF TestBed (OTB) simulation that used SIMNET and CCTT soil codes in the digital terrain database to provide fine-grained soils with appropriate mobility response for computer-generated entities.
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Standard ideas can be used in singularity theory to classify, up to local diffeomorphism, the affine focal set. If the family of affine distance functions can be shown to be a certain kind of family then the local structure is known. The family of affine distance functions should be a versal unfolding of the singularities which arise.
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To date, for both the FDA and the EMA, ncRNAs are considered as "simple" medical products because of their production by chemical synthesis. When some of them, produced biologically (know as bioengineered ncRNA agents: BERAs), will be put on the market, the status of biological medical products will be applied, which could lead to inconsistencies in the legislation.
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Chair: Viviana Fluxa (Switzerland); Secretary: Cristina Todaşcă (Romania); Relationship with industries: Lineke Pelleboer (The Netherlands); External communication: Guillaume Poisson (France); Membership and internal communication: Aurora Walshe (UK); Website designer: Magorzata Zaitz (Poland)
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Nel et al. (1993) suggested that Recent Epiophlebiidae is the sister group of Stenophlebiidae within a superfamily Epiophlebioidea, and Bechly (1996) suggested that extinct Gondvanogomphidae is the sister group of Stenophlebiidae within Stenophlebioptera. However, these hypotheses have been refuted by Fleck et al. (2003).
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The GIEESC’s two goals for India were to train existing professionals in life saving skills, and to implement a “rural surgery” project where surgeons would be trained to deal with specific surgical problems seen in rural areas.
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The Situational Awareness (SA) Server was an interface between the simulation and tactical networks. It provided Level 1 Sensor Fusion using a Kalman filter. The tactical network it supported used experimental DIS PDUs for the blue and red Common Operating Picture (COP). It also supported an early version of the NetFires system for semi-automated fire support. Multiple SA Servers could be configured in a multi-cell arrangement to use communications effects as defined by a comms model like ALCES or QualNet.
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The affine focal set of a plane curve will generically consist of smooth pieces of curve and ordinary cusp points (semi-cubical parabolae).
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ASO’s are single-stranded DNA molecules with full complementarity to one select target mRNA and may act by blocking protein translation (via steric hindrance), causing mRNA degradation (via RNase H-cleavage) or changing pre-mRNA splicing. These short oligonucleotides have already been approved by the FDA for ten genetic disorders and many are currently in the pipeline to be approved/tested. Using oligonucleotide technology, we are now able to control protein expression via RNA interference, and are able to affect previously defined “undruggable” proteins. Even though this therapy has a lot of promise and potential, it comes with many limitations.
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Key achievements: Development of the EYCN's website and active participation at the 3rd EuCheMS Chemistry Congress (ECC3) in Nuremberg, 2010.
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The phylogenetic position of Stenophlebiidae according to Bechly (1996, 2007) and Fleck et al. (2003, 2004):
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The country’s government was implementing health care reform by focusing on surgery, and a WHO toolkit was to be implemented at medical institutions to help.
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The Tech Control was a collection of tools that monitored a widely distributed simulation to ensure that configuration management and network performance standards were met. The tools, like the Reporter, the Exercise Manager, and the NetRouter, allowed Tech Control personnel to manage large exercises like COIN with high simulation availability.
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The affine focal set of a surface in three-space will generically consist of smooth pieces of surface, cuspidal cylinder points (formula_53), swallowtail points (formula_54), purse points (formula_55), and pyramid points (formula_56). The formula_57 and formula_58 series are as in Arnold's list.
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Compared to siRNA and microRNA, ASOs are more versatile in reducing protein expression, they have the ability to also enhance target translation. ASOs can also be customized with ease and accuracy, allowing for the targeting of virtually any mutated gene. This allows for a greater level of application in the field of precision and personalized medicine.
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Chair: Sergej Toews (Germany); Secretary: Helena Laavi (Finland); Relationship with industry: Viviana Fluxa (Switzerland); Communications: Dan Dumitrescu (Romania); Scientific affairs: Ilya Vorotyntsev (Russia)
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Next to nothing is known about the ecology and behavior of Stenophlebiidae, but it probably was quite similar to Recent odonates. The shape of the wings suggests that they were slow flyers that fed on smaller flying insects. The females probably inserted their eggs into plants in or close to the water.
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GIEESC had begun anesthesia training at sites in Faryab and Mazir-I Sharif, and equipment was donated for the purpose.
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Data Collection and Analysis was primarily based on the collection and correlation of network simulation traffic (DIS PDUs). The data were written to flat files or directly to a Relational Database where they were further processed and analyzed to produce charts, graphs, tables, spreadsheets and presentations for the use of Army Operations Research / Systems Analysts (ORSAs).
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The question of the local structure in much higher dimension is of great interest. For example, it is possible to construct a discrete list of singularity types (up to local diffeomorphism). In much higher dimensions, no such discrete list can be constructed, as there are functional moduli.
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The main challenge of ASO therapies to specific tissues and cellular uptake is what poses a great challenge and limitation. Liposomal delivery is one such way to overcome such issues. Liposomal delivery system comes with its own share of limitations. Serum proteins in the bloodstream destabilize the lipoprotein. This destabilization leads to the depletion of protein and exposing cargo to the unstable environment. This hindrance can be overcome by using PEGs (poly(ethylene glycol) . However, PEGs are not biodegradable causing them to accumulate within the body leading to adverse effects and causing hypersensitivity. In addition, multiple rounds of therapy with PEGs can lead to the formation of PEG antibodies, which can lead to lack of efficiency in preventing the rupture of the liposome that it is attached to.
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Chair: Csaba Janáky (Hungary); Secretary: Emma Dumphy (Switzerland); Treasurer: Juan Luis Delgado de la Cruz (Spain); Sponsor relations officer: Jens Breffke (Germany); Communications Officer: Cristina Todaşcă (Romania)
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The fossil record of this family ranges from Upper Jurassic of Germany (Solnhofen Plattenkalk, Nusplingen limestones) and Kazakhstan (Karabastau Svita) to the Lower Cretaceous of Brazil (Crato Formation), Mongolia (Bon Tsagaan), Spain (Las Hoyas), and England (Durlston Formation) to the Upper Cretaceous (Cenomanian) of France and Myanmar.
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The country’s health care budget was being redirected toward training of health care providers at basic facilities with surgical capabilities, with essential and emergency surgical care education central to the project.
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The VirtuSphere was a single-soldier manned simulator that incorporates a large sphere that allows a human to walk around the simulated battlefield (like a hamster in a ball). It was based on the ACRT technology, and was used at the MWTB for experiments that examine future weapon systems and tactics and for evaluating soldier behavior.
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Using immunoliposomes it has been shown that targeting can be more specific as by using antibody’s specific to the protein of expression in that area, it results in the ASO drug directly impact the target site and nowhere else. Moreover, immunoliposomes are slow to dissociate leading to precise release of the ASO drug which they encapsulate.
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The first stenophlebiid fossil was described as ""Agrion"" "latreillei" by Germar (1839) from the Upper Jurassic Solnhofen Plattenkalk of Germany.
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The GIEESC was involved in various collaborations with other WHO departments: Transplantation, Health Action in Crises, Violence and Injury Prevention, Making Pregnancy Safer, Child and Adolescent Health, The Partnership for Maternal, Newborn, and Child Health, Communicable Diseases, Second Global Patient Safety Challenge: Safe Surgery Saves Lives, Health Inter Network Access to Research Initiative, Knowledge Management for Public Health, and the Clinical Procedures Unit. The GIEESC was also involved in global partnerships with: The Transplantation Society, Medecins Sans Frontiers, International Committee of the Red Cross, International Society of Orthopedic Surgery and Traumatology, Health Volunteers Overseas, Association of Surgeons of East Africa, College of Surgeons of East, Central and South Africa, International Federation of Surgical Colleges, International College of Surgeons, World Federation of Societies of Anesthesiologists, Geneva Foundation for Medical Education and Research, EHT-ESC WHO/UNICEF Statement on Anemia, and the Canadian Network for International Surgery.
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The simulator was frequently seen at trade shows and science festivals, like the USA Science Festival, the San Diego Science Festival and the Jackson IT Day. It was typically one of the most popular exhibits.
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Long noncoding RNAs (lncRNAs) are large transcripts (more than 200 nucleotides long) that have similar mechanism of synthesis as that of mRNAs but unlike mRNAs, lncRNAs are not translated to a protein. lncRNA contains interactor elements and structural elements. Interactor elements directly interact with other nucleic acids or proteins while the structural elements indicate the ability of some lncRNAs to form secondary and/or tertiary structures. This ability of the lncRNAs to interact with nucleic acids using its interactor elements and its ability to interact with protein using its secondary structures allows it to function in a more diverse manner than other ncRNAs such as miRNA (microRNA). LncRNA has been established to play a role in gene regulation by influencing the ability of specific regions of the gene to bind to transcriptional elements and different epigenetic modifications. One such example can be seen in the case X inactive specific transcript (XIST). In humans, 46,XX females carry an extra X chromosome (155Mb of DNA) compared to 46,XY males. To overcome this dosage imbalance, one X chromosome is randomly inactivated in human females at around the 2-8 cell stage of embryo development. This inactivation is very stable across cell divisions due to epigenetic contributions both during the initial silencing and the subsequent maintenance of the inactive X chromosome (Xi). This inactivation is carried by the lncRNA, XIST. XIST is produced in cis and inactivates the X-chromosome that it has been generated from. The inactive X chromosome can be observed as a condensed heterochromatin structure called “Barr Body”.
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Beside the important type specimens there are also several exceptionally well preserved fossils that contribute to our knowledge of the morphology of Stenophlebiidae. These include specimens of "Stenophlebia amphitrite" and "Stenophlebia latreillei" in several private fossil collections.
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A study in 2013 utilized this ability of XIST as a potential therapeutic approach for treatment of trisomy 21. Trisomy 21 is commonly known as down syndrome and is caused due to presence of an additional copy of chromosome 21. The study was one of its kind as no other studies have been able to incorporate the XIST gene into a chromosome due to its large size. The study incorporated the XIST into one of the chromosomes 21 in the cells gathered from patients with down syndrome. The study was able to observe the inactivation of one of chromosome 21 in the form of a condensed heterochromatin and labeled it as a chromosome 21 barr body. Such experiments have shown to work in cells in the lab setting although no lncRNA based therapeutics are in clinical trials. The implications of such work can bring trisomy 21 and other chromosomal disorders in the realm of consideration for future gene therapy research.
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One of the major issues that hinders the ncRNA therapy is the stability of the single stranded RNA molecule. RNA is typically single stranded therefore slightly unstable as compared to dsDNA molecules. This however can be overcome by fabricating the single stranded RNA to double stranded RNA(dsRNA). This is quite effective as the dsRNA is more stable at room temperature and has a longer shelf life.
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Second major issue is the cell/tissue/organ specific targeting of the RNA molecules. Generally, this is overcome by containing the dsRNA in a lipid nanoparticle and using that as a ligand to bind to a receptor on the surface of the target cell. The lipid particles are taken into the liver cells through their specific receptors and this mechanism seems to be effective at targeting the liver cells/cancer.
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Another organ with a relatively easy delivery mechanism is the eye. This requires an invasive technique of directly injecting the ncRNA of interest directly into the eye. These techniques are not only invasive but also don’t ensure if all the cells in the target organ are being targeted by the ncRNA of interest.
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Additional issues arise once the RNA molecule enters the cell. One of the issues being the immune system. Our immune system can recognize RNA using the intracellular pathogen associated molecular pattern (PAMP) receptors and extracellular toll-like receptors (TLR). Activation of the receptors leads to a cytokine (IFNy-Interferon gamma) mediated immune response. Common applications to overcome the immune response include second generation chemical modifications. This process includes the introduction of small one at a time chemical modifications to avoid the immune response. However, there are some reports of adverse immune responses in clinical trials employing such modified reagents. There’s no fixed answer to issues with immunogenicity and ncRNA therapy.
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Modified adenovirus vectors have been used extensively in many clinical trials as a ncRNA delivery mechanism. In particular, adenovirus vector is considered an efficient delivery system due to its stability within live cells and non-pathogenicity. Even though viral transfections have achieved significant results in basic research, one of the issues is the non-specificity leading to off target transfections. Further research needs to be done to improve the accuracy of viral transfections for future tests and clinical trials.
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In December 2021, the FDA came up with a draft guidance for the use of ASO drug products. This draft guidance was directed towards sponsor-investigators who are developing individualized investigational antisense oligonucleotides (ASO) drug products for severely debilitating or life threatening diseases. Severely debilitating corresponds to a disease or condition that causes major irreversible morbidity. However, life-threatening is defined as the disease or condition has a likelihood of death unless the course of treatment leads to an endpoint of survival. Usually individuals that have a severely debilitating life threatening disease don't have any alternative treatment options, and their diseases will be rapidly progressing, leading to an early death and/or devastating or irreversible morbidity within a short time frame without treatment.
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Drug development is usually targeted for a large number of individuals, in this case that is not possible because of the specificity of the mechanism of action of the ASO combined with the rarity of the treatment-amenable patient population. Under FDA regulations, a protocol under which an individual ASO product is administered to a human subject must be reviewed and approved by an institutional review board (IRB) before it can be administered to human subjects. When the individual is a child, additional safeguards need to be identified in order to prevent any developmental issues from occurring that may affect the life of the individual. The sponsor-investigator needs to get informed consent from the individual or from the person who is responsible for the individual. The consent needs to include a description of reasonably foreseeable risks or discomforts as part of the use of the ASO drug. The sponsor also needs to get individuals clinical and genetic diagnosis to confirm that the ASO will be beneficial. The analysis may be through gene sequencing, enzymatic analysis, biochemical testing, imaging evaluations. All results need to be included in the application. Also the sponsor needs to include evidence that establishes the role of the gene variant targeted by the ASO drug. The sponsor/investigator need to also provide evidence that the identified gene variant or variants are unique to the individual.
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The guidance suggests that the starting dose should be based on available non-clinical data that has been collected from model organisms or in vitro studies and should be in correlation with other ASO drug product dosing information that is available. At the starting dose, pharmacological effects are expected. Furthermore, It is advised that a dosing escalation method be utilized. This includes the step of escalating the dodge from its initial dose based on pharmacodynamic effects and/or trial participants' response to the ASO.
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In addition, protocols submitted to the FDA need to have a clear dosing plan and justification for selecting the starting dose, dosing interval, and plan for dose escalation or dose reduction based on clinical pharmacodynamic effects of the drug on the individual. Also all anticipated outcomes should be included in the drug plan when submitted to the FDA. It is extremely important for the investigators to monitor the patient closely during dose escalation. During the escalation period, adequate time should be provided in order to see therapeutic results. It is advised that the investigator not make concurrent changes to the dosing interval along with the dose without justification. The submitted plan should include a de-escalation/discontinuation plan if toxicity is observed. All drug administration needs to take place in an inpatient setting just to get a grasp of the adverse effects the drug may have. Once drug toxicity, beneficiancy and adverse effects are identified, the drug can be administered in an outpatient manner as long as the same concentration of drug is administered.
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The Women's 4×100 Freestyle Relay event at the 11th FINA World Aquatics Championships swam on 24 July 2005 in Montreal Canada.
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Plasmodium booliati is a parasite of the genus "Plasmodium" subgenus "Vinckeia". As in all "Plasmodium" species, "P. booliati" has both vertebrate and insect hosts. The vertebrate hosts for this parasite are mammals.
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Mark Keil (born 1960) is a Regents’ Professor and the John B. Zellars Professor of Computer Information Systems in the J. Mack Robinson College of Business at Georgia State University. He also holds appointments in the Department of Computer Science and the Institute of Health Administration at Georgia State University.
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His research examines managerial decision-making, specifically in the context of IT projects and includes work on project escalation, project status reporting, project risk, and project control, project manager skills, and technology acceptance.
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He has served as a Division Chair for the Communication, Digital Technology, and Organization (CTO, formerly known as OCIS) Division of the Academy of Management. He has also held a variety of editorial positions for journals such as "Information Systems Research", "MIS Quarterly", "Journal of Management Information Systems", "Decision Sciences", "Information Systems Journal", "IEEE Transactions on Engineering Management", and "The Data Base for Advances in Information Systems".
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Keil has given many research talks at U.S. universities and has also held short visiting appointments abroad at the National University of Singapore, Australian National University, Erasmus University Rotterdam, University of Göttingen, Goethe University, University of Bamberg, and Swinburne University of Technology.
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In 1982, he obtained his Bachelor of Science in Engineering (B.S.E.) from Princeton University. He obtained his Master’s degree (S.M.) from the MIT Sloan School of Management in1986. He obtained a doctoral degree (D.B.A.) in Management Information Systems from the Harvard Business School (HBS) in 1991.
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He started his career at DuPont's Experimental Station after completing his B.S.E. degree in Chemical Engineering. After completing his Master's degree, he worked as a project manager and consultant in the information systems area before enrolling in the HBS doctoral program. During his doctoral studies, he worked as an instructor at the Harvard University Extension School.
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In 1991, after completing his doctoral degree, he began his academic career as an Assistant Professor at Georgia State University. He was tenured and promoted to the rank of associate professor in 1997 and full professor in 2002.
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Keil has published 130 peer-reviewed journal articles in such publications as "Information Systems Research", "MIS Quarterly", "Journal of Management Information Systems", "Decision Sciences", "Strategic Management Journal", "IEEE Transactions on Engineering Management", "Sloan Management Review", and "California Management Review". Google Scholar indicates that his work has earned over 25,000 citations.
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Keil’s work (with co-author Anandhi Bharadwaj of Emory University) on the market impact of IT failures was featured in "Baseline" in 2001 titled "Bada Boom". The article noted that “on average, the stocks of publicly traded companies decline 1.75% as negative news emerges” involving an IT failure. This “decline translated into the disappearance, on average, of $650 million in stock-market value over a two-day period.”
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He is regularly contacted as an expert by the media; interviews have appeared in "CBS News", "BusinessWeek" (now part of Bloomberg), "Computer World", "Baseline", "Network World", "ScienceDaily", "The Atlanta Journal-Constitution" and "Carrier Management".
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In 2005, Mark Keil received Georgia State University’s Alumni Distinguished Professor Award, 2005 which recognizes a high-achieving senior Georgia State faculty member who embodies the balance between teacher and scholar.
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He is also a two-time recipient of the J. Mack Robinson College of Business Faculty Recognition Award for Distinguished Contributions in Research (2000 and 2009). He has also received many best paper awards from the AOM's CTO Division as well as from journals such as the "Journal of Strategic Information Systems, Decision Sciences, and IEEE Transactions on Engineering Management".
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He was named the John B. Zellars Professor of Computer Information Systems. In 2016, he was named a Distinguished University Professor. This appointment recognizes professors who have records of exemplary scholarship in their respective fields of study, and whose research and teaching trajectories demonstrate a commitment to sustained high levels of academic achievement.
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In 2018, he received the Project Management Institute’s Research Achievement Award. In the same year, he received the AIS Fellow Award from the Association for Information Systems. This award recognizes individuals who have made outstanding contributions to the Information Systems discipline in terms of research, teaching, and service.
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In 2019, he was appointed as a Regent’s Professor of the University System of Georgia. This is the highest academic honor in the University System of Georgia. It is bestowed on professors whose scholarly achievements are recognized nationally and internationally as innovative and renowned and who have a record of sustained scholarly productivity as well as substantial contributions in service to their discipline and Georgia State University.
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The Mycocaliciales are an order of ascomycetous fungi within the subclass Mycocaliciomycetidae and within the class Eurotiomycetes (subphylum Pezizomycotina).
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Colus gracilis is a species of sea snail, a marine gastropod mollusk in the family Buccinidae, the true whelks and the like.
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A smooth form with flatter whorls, 40 to 100 mm in length, but a highly variable species that occurs in several morphologically different geographical and bathymetrical forms; these forms may look identical over large areas, then give an impression that several near species are involved.
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The wingspan is 12–16 mm.16–20 mm. The forewing has a brown dorso-basal blotch, From the apex there is a costal streak chequered brown and cream, edged with black, reaching to a cream cross-line.
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The moth flies from late April to June and again from July to September in two generations, although this might be dependent on the location.
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The Arctomiaceae are a family of lichenized fungi in the Ascomycota, class Baeomycetales. The family was named by Theodor Magnus Fries in 1861, with "Arctomia" as the type genus. Species in this family are found in arctic and subarctic habitats, usually associated with bryophytes.
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The order Arctomiales was proposed by Soili Stenroos, Jolanta Miadlikowska, and François Lutzoni in 2014 to contain this family. In 2018, the class Lecanoromycetes was revised using a temporal approach that uses time-calibrated chronograms to define temporal bands for comparable ranks for orders and families. In this work, the orders Arctomiales, Hymeneliales, and Trapeliales were synonymized with Baeomycetales. In a subsequent review of the use of this method for biological classification of lichens, Robert Lücking considered this merge justified. This synonymy was also accepted in later compilations of fungal classification, and Arctomiaceae is classified in the order Baeomycetales.
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https://en.wikipedia.org/wiki?curid=24738666
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2,243,672 |
Genus "Gabura" was resurrected for use in 2020 and contains three species formerly placed in "Arctomia".
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https://en.wikipedia.org/wiki?curid=24738666
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2,243,673 |
Gentianella barringtonensis, the Barrington snow gentian, is a species of the genus "Gentianella" native to New South Wales, Australia.
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https://en.wikipedia.org/wiki?curid=47785811
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2,243,674 |
Øjvind Moestrup (born 15 December 1941) is a Danish aquatic botanist, working particularly with the classification of algae. He worked at the Botanical Institute at the University of Copenhagen and is a professor emeritus in the Department of Biology there. He published over 100 scientific papers.
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https://en.wikipedia.org/wiki?curid=9524599
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2,243,675 |
Moestrup received his doctorate in biology from the University of Copenhagen in 1983, and has worked with the Fishery Inspection Service of the Danish Ministry of Fisheries. His major areas of research include the taxonomy of planktonic algae, haptophytes, toxic diatoms and raphidophytes.
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https://en.wikipedia.org/wiki?curid=9524599
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2,243,676 |
In 2012 Professor Moestrup received the Yasumoto Award for excellence in his lifetime dedicated work of research on the biology, taxonomy and ultrastructure of microalgae.<ref name="ISSHA/HAB*"></ref>
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https://en.wikipedia.org/wiki?curid=9524599
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2,243,677 |
The Coptacrinae are a subfamily of Acrididae (originally described by Brunner von Wattenwyl under the synonym: Coptacrae) in the Orthoptera: Caelifera. Species can be found in Africa and Asia.
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https://en.wikipedia.org/wiki?curid=56477918
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2,243,678 |
In enzymology, a S-methyl-5-thioribose-1-phosphate isomerase () is an enzyme that catalyzes the chemical reaction
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https://en.wikipedia.org/wiki?curid=14217558
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2,243,679 |
In enzymology, a digalactosyldiacylglycerol synthase () is an enzyme that catalyzes the chemical reaction
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https://en.wikipedia.org/wiki?curid=14650971
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2,243,680 |
Hence, this enzyme has one substrate, S-methyl-5-thio-alpha-D-ribose 1-phosphate, and one product, S-methyl-5-thio-D-ribulose 1-phosphate.
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https://en.wikipedia.org/wiki?curid=14217558
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2,243,681 |
Thus, the two substrates of this enzyme are UDP-galactose and 3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol, whereas its 3 products are UDP, 3-[alpha-D-galactosyl-(1->6)-beta-D-galactosyl]-1,2-diacyl-sn-, and glycerol.
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https://en.wikipedia.org/wiki?curid=14650971
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2,243,682 |
This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is S-methyl-5-thio-alpha-D-ribose-1-phosphate aldose-ketose-isomerase. Other names in common use include methylthioribose 1-phosphate isomerase, 1-PMTR isomerase, 5-methylthio-5-deoxy-D-ribose-1-phosphate ketol-isomerase, S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate ketol-isomerase, S-methyl-5-thio-5-deoxy-D-ribose-1-phosphate, aldose-ketose-isomerase, 1-phospho-5'-S-methylthioribose isomerase, and S-methyl-5-thio-D-ribose-1-phosphate aldose-ketose-isomerase. This enzyme participates in methionine metabolism.
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https://en.wikipedia.org/wiki?curid=14217558
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2,243,683 |
This enzyme belongs to the family of glycosyltransferases, specifically the hexosyltransferases. The systematic name of this enzyme class is UDP-galactose:3-(beta-D-galactosyl)-1,2-diacyl-sn-glycerol 6-alpha-galactosyltransferase. Other names in common use include DGD1, DGD2, DGDG synthase (ambiguous), UDP-galactose-dependent DGDG synthase, UDP-galactose-dependent digalactosyldiacylglycerol synthase, and UDP-galactose:MGDG galactosyltransferase. This enzyme participates in glycerolipid metabolism.
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https://en.wikipedia.org/wiki?curid=14650971
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2,243,684 |
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes and .
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https://en.wikipedia.org/wiki?curid=14217558
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2,243,685 |
Formerly he was thought to be the same person as Richard of Wendover, but, according to Faye Getz, this now seems unlikely.
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https://en.wikipedia.org/wiki?curid=71372671
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2,243,686 |
Ethiopia was one of 28 nations to send a delegation to the 1968 Summer Paralympics in Tel Aviv, Israel from November 4 to 13, 1968; two Ethiopian athletes competed, both of them men. Abraham Habte and Negatu each took part in both athletics and table tennis events. The team did not win any medals at these Games and, as of the 2010 Winter Paralympics, no Ethiopian athlete has won a medal at either the Summer or Winter Paralympics.
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https://en.wikipedia.org/wiki?curid=31813636
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2,243,687 |
WSML or Web Service Modeling Language is a formal language that provides a syntax and semantics for the Web Service Modeling Ontology (WSMO).
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https://en.wikipedia.org/wiki?curid=18796726
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2,243,688 |
Coprothermobacterales is a new taxonomic order of thermophilic bacteria in the class Coprothermobacteria of the phylum Coprothermobacterota.
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https://en.wikipedia.org/wiki?curid=59018241
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2,243,689 |
The 1980 Individual Speedway Junior European Championship was the fourth edition of the European Under-21 Championships.
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https://en.wikipedia.org/wiki?curid=12802712
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2,243,690 |
The name "Ricardus Anglicus", in the context of the middle ages, is ambiguous, because it is merely the Latin for "Richard from England". He should not be confused with the English lawyer and cleric Richard de Morins (), who was also known as Richardus Anglicus, nor with the bishop Richard Poore (died 1237) who was also (falsely) referred to by that name.
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https://en.wikipedia.org/wiki?curid=71372671
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2,243,691 |
Negatu entered five athletics events; club throw C, shot put C, javelin C, the open precision javelin and 100 metres wheelchair C. He failed to advance to the finals in any of the events finishing 17th in the 100 metres, 38th in the club throw with a distance of 20.46 metres, 32nd in javelin with a throw of 12.90 metres, 65th in precision javelin with a score of 65 and 22nd in the shot put with a throw of 6.01 metres.
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https://en.wikipedia.org/wiki?curid=31813636
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2,243,692 |
In other words, the WSML provides means to formally describe the WSMO elements as Ontologies, Semantic Web services, Goals, and Mediators.
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https://en.wikipedia.org/wiki?curid=18796726
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2,243,693 |
Its name derives from the type genus of this order, "Coprothermobacter", with the ending suffix '-ales', to denote an order.
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https://en.wikipedia.org/wiki?curid=59018241
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2,243,694 |
Ricardus Anglicus, cleric and medical doctor, wrote a compendium of medicine, entitled "Micrologus", while at the University of Montpellier, on the instructions of Lancelinus de l'Isle-Adam, who was deacon of Beauvais from 1178 to 1190. From this we know that the work was not completed after 1190, which excludes Richard of Wendover as the author. Further evidence comes from Gilles de Corbeil (died 1224), also a professor in Montpellier and author of works on urine and the pulse, who writes positively of a doctor "Richardus senior" in Montpellier, but who does not call him "Anglicus".
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https://en.wikipedia.org/wiki?curid=71372671
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2,243,695 |
Abraham Habte competed in the men's club throw C and precision javelin events but did not make either final. He scored 56 points in the precision javelin to earn 53rd position and finished 41st in the club throw with a distance of 18.82 metres.
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https://en.wikipedia.org/wiki?curid=31813636
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2,243,696 |
The WSML is based on the logical formalisms as Description Logic, First-order Logic and Logic Programming.
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https://en.wikipedia.org/wiki?curid=18796726
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2,243,697 |
The bacteria of this order have a rod-shaped morphology, do not produce spores, are nonmotile, strictly anaerobic and, being thermophiles, grow at temperature ranges above 35°C and below 70°C, for a pH between 5.0 and 9.4. Moreover, these bacteria are chemoorganotrophs and proteolytic fermenters, which produce acetic acid, H, and CO as main end-products of fermentation.
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https://en.wikipedia.org/wiki?curid=59018241
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2,243,698 |
The "Micrologus" has not survived complete, but various texts identified with the name Ricardus Anglicus appear to be parts of it. There are also further medical texts distributed under his name whose relationship to the "Micrologus" is doubtful.
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https://en.wikipedia.org/wiki?curid=71372671
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2,243,699 |
Habte and Negatu both entered the men's singles C classification and teamed up in the doubles C. In the singles Negatu was eliminated in the first round and Habte was eliminated in the second round; the gold medal was won by Baruch Hagai for host nation Israel. In the doubles the Ethiopian pair was eliminated by the eventual gold medalists, Israel's Hagai and Arieh Rubin, in the first round.
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https://en.wikipedia.org/wiki?curid=31813636
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