corpusid
int64 5
255M
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stringlengths 1
10k
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24
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|---|---|---|---|
55,144,928 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5897/ajb2004.000-2056",
"MAG": "3015622677",
"PubMedCentral": null
},
"license": "CCBY",
"status": "HYBRID",
"url": "https://academicjournals.org/journal/AJB/article-full-text-pdf/061915632687"
}
|
Maize (Zea mays) is a major important cereal being cultivated in the rainforest and the derived Savannah zones of Nigeria. Land races, improved high yielding and pest and diseases resistant varieties of maize have been developed.
Key words: Maize, Zea mays, Nigeria.
|
2023-01-01T19:11:55.111Z
|
209,627,561 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1246/nikkashi1948.80.11_1270",
"MAG": "623290316",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://www.jstage.jst.go.jp/article/nikkashi1948/80/11/80_11_1270/_pdf"
}
|
2-オキシ-1-ナフトアルドキシムは亜鉛とpH4.6より沈殿しはじめ,pH9以上のアンモニア性溶液で定量的に反応してC11H7-02NZnの組成の沈殿を生成する。この沈殿は0.1N程度の酸によって容易に分解されるので,ロ紙上の沈殿に0.1Nの硫酸の一定量を加え,ロ液中の過剰の酸を0.1Nの水酸化ナトリウム溶液で滴定して亜鉛錯塩を分解するに要した硫酸の量をもとめる。分解に要した0.1Nの硫酸1mlは亜鉛の3.269mgに相当する。銅およびニッケルが共存するときにはこれらの金属をpH4.6以下の酢酸酸性で本試薬で沈殿させ,ついでpHを9以上にして亜鉛を沈殿させる方法によれば銅およびニッケルの共存による妨害を受けない。
|
2022-02-08T03:41:16.224Z
|
172,504,163 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1501/ANKARA-489",
"MAG": "140052440",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Bazi amino asitlerin (L-Serin, L-Metiyonin, L-Sistein L-Lizin, L-Triptofan, L-Tirozin, L-Glutamik Asit, L-Aspartik Asit, L-Arginine, L-Asparagin, L-Glutamin) 2-hidroksi-1-naftaldehit ile Schiff bazlari hazirlanmistir. Bu Schiff bazlarinin acik yapilarinin aydinlatilmasinda element analizi, IR, UV, 1H-NMR, Kutle Spektroskopisi ve X isinlari Difraksiyon Metodundan yararlanilmistir. Ayrica bu Schiff bazlarinin bazilarinin mangan(III) kompleksleri sentezlenmis ve yapilari element analizi, IR, UV, TG (Thermogravimetri), Kutle Spektroskopisi, Magnetik Susseptibilite metodlarindan yararlanilarak aydinlatilmaya calisilmistir.
|
2022-02-08T16:20:26.004Z
|
62,729,043 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4028/www.scientific.net/AMM.610.888",
"MAG": "2027767290",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
From the point of view to improve QoS of Ad Hoc network, this paper analyses the problem about mobile nodes in Ad Hoc network and decides to solve the problem by designing effective MAC protocol. Therefore, a novel random multi-access protocol using Binary Tree Collision Resolution for collision packets in Probability-Persistent Random Multi-Access (IBTCRPP-CSMA) is proposed. The throughput of IBTCRPP-CSMA and computer simulation experiments are obtained. Simulation results agree with theoretical analysis. By contrasts of throughputs among several CSMA protocols, IBTCRPP-CSMA has higher throughput and channel utilization, thereby ensuring the system’s high QoS.
|
2022-02-11T14:25:17.217Z
|
147,989,500 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21564/2414-990X.132.59347",
"MAG": "2403773089",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The paper addresses a reasonable time of a trial as an element of art. 6 (1) of European Convention on Human Rights within the conception of judicial time management. The author analyses specific features of the judicial time management according to the studies of the European Commission for the Efficiency of Justice (CEPEJ).
|
2022-05-20T07:22:44.785Z
|
218,780,839 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1096/fasebj.2020.34.s1.03568",
"MAG": "3017048834",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The G protein alpha subunit o (Gαo) is abundantly expressed in the nervous system and pathogenic mutations in its gene (GNAO1) cause movement disorder. In contrast to the other Gα subunits, Gαo has been relatively understudied and its function remains mechanistically ill defined. Using biochemical assays, optical imaging in primary neurons, and genetic mouse models we define mechanisms of Gαo action on the cAMP generating enzyme – adenylyl cyclase (AC) in a neuron subtype selective manner. Here, we show that Gαo transduces striatal signals to enable motor learning by opening an alternate signaling channel regulating dynamics of neuromodulatory interrogation of dopamine to the second messenger cAMP. We find that Gαo is a critical modifier of striatal AC activity through horizontal interplay with other G protein subunits. Gαo modulates Gβγ availability to impact processing of signaling by AC that sensitizes stimulatory inputs (Gαs/olf) while diminishing efficacy of inhibitory inputs (Gαi). These processes accompany adjustments in electrophysiological properties of striatal neurons that compromise motor learning in a circuit‐selective fashion. Based on our findings we propose a model for Gαo in programming motor command processing of GPCR signals to cAMP.
|
2022-06-18T14:05:47.388Z
|
249,981,336 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1755-1315/1041/1/012079",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://doi.org/10.1088/1755-1315/1041/1/012079"
}
|
This study evaluated the micro-enterprise production practices and microbiological properties of Philippine pork sausage. It was noted that most sausage manufacturers that fall under the said business category require workers to take a bath prior to operation and wear aprons while few require hand washing and use of hairnet and facemask. No one used hand gloves. Meat materials are sourced locally and undergo no washing prior to grinding which are mostly facilitated at room temperature. Only few of the respondents have designated processing area while others process in-store or at the back of their house. All the respondents use stainless steel mixing basin and manual stuffing with 46.67% using stainless steel table. Processors use hog casing and/or artificial edible casing. Results of the microbial analysis showed all sausage samples were beyond the limit for coliforms while only 26.77% were below the limit set for Escherichia coli. Salmonella had 93.33% incidence while all samples were tested positive for Staphylococcus aureus. Results showed that micro-enterprise production process of local pork sausage may compromise the safety of the consuming public and comprehensive evaluation by the local government unit is necessary to comply with the Philippine Food Safety Act of 2013.
|
2022-07-04T21:11:11.436Z
|
119,825,790 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1142/S1793524514500053",
"MAG": "1984832726",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The aim of this paper is to present a continuum model for bioconvection of oxytactic micro-organisms in a non-Darcy porous medium and to investigate the effects of bioconvection and mixed convection on the steady boundary layer flow past a horizontal plate embedded in a porous medium filled with a water-based nanofluid. The governing partial differential equations for momentum, heat, oxygen and micro-organism conservation are reduced to a set of nonlinear ordinary differential equations using similarity transformations that are numerically solved using a built-in MATLAB ODE solver. The effects of the bioconvection parameters on the nanofluid fluid properties, nanoparticle concentration and the density of the micro-organism are analyzed. A comparative analysis of our results with those previously reported in the literature is given. Among the significant findings in this study is that bioconvection parameters highly influence heat, mass and motile micro-organism transfer rates.
|
2022-10-29T17:52:09.760Z
|
137,153,587 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/PEN.760150806",
"MAG": "1975951859",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The basic idea of automatic control of extrusion machinery is considered. Dynamic interaction among process variables is discussed and it is suggested that a practical form of control might involve steady-state control of screw and barrel temperature coupled with dynamic control of screw speed. Several alternative forms of control strategy are examined and it is suggested that for higher forms of control, a computer is required together with an accurate process model relating control and controlled variables. With such a strategy, polymer temperature and pressure at the die would be controlled by continuous variations in screw speed coupled with infrequent control of die resistance to counter long term drift and to facilitate pressure and temperature change matching. Methods for developing process models are considered including those for adaptive/predictive control strategies using time-series techniques and some experimental results are given. The basic form of a computer control system is outlined and the areas where further research is required are indicated.
|
2022-10-03T16:37:48.661Z
|
195,883,543 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CIFEr.2019.8759119",
"MAG": "2960715812",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
For financial market participants, the current focused topic (Brexit, Federal Reserve Interest-Rate, U.S. and China trade war, etc.) and its sentiments (whether it is Risk-On or Risk-Off) is very important to decide investment strategies. In this study, we proposed extended topic model called supervised Joint Sentiment-Topic model (sJST) which using not only text data but also numeric data as a supervised signal to extract current focused topic and it's sentiment of market. By using the topic and sentiment weight of the market as a features, we apply several machine learning models to predict foreign exchange market price movement. Comparing the average accuracy over 32 currency pairs and prediction models, the result using sJST weight as features achieved 1.52% better performance than the results which use only historical prices as features. Furthermore, comparing the results limited to specific currency pairs which is difficult to predict when using only historical prices as features, the result using sJST weight as features achieved 3.64% better accuracy than the result which use only historical prices as features.
|
2022-10-03T16:46:18.575Z
|
199,103,765 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1130/B31996.1",
"MAG": "2960156931",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We present a new, biostratigraphically calibrated organic and inorganic C-isotope record spanning the basal Late Permian to earliest Triassic from southern Guizhou (Nanpanjiang basin, South China). After fluctuations of a likely diagenetic overprint are removed, three negative carbon isotope excursions (CIEs) persist. These include a short-lived CIE during the early Wuchiapingian, a protracted CIE ending shortly after the Wuchiapingian–Changhsingian Boundary, and a third CIE straddling the Permian–Triassic boundary. Comparison of our new C-isotope record with others from the same basin suggests that influences of local bathymetry and of the amount of buried terrestrial organic matter are of importance. Comparison with other coeval time series outside of South China also highlights that only the negative CIE at the Permian–Triassic boundary is a global signal. These differences can be explained by the different volumes of erupted basalts between the Late Permian Emeishan and the younger Siberian large igneous provinces and their distinct eruptive modalities. Emeishan volcanism was largely submarine, implying that sea water was an efficient buffer against atmospheric propagation of volatiles. The equatorial position of Emeishan was also an additional obstacle for volatiles to reach the stratosphere and benefit from an efficient global distribution. Consequently, the local significance of these CIEs calls into question global correlations based on C-isotope chemostratigraphy during the Late Permian. The timing of the Late Permian Chinese CIEs is also not reflected in changes in species diversity or ecology, unlike the sudden and global Permian–Triassic boundary crisis and subsequent Early Triassic upheavals.
|
2022-11-29T07:19:24.786Z
|
195,546,968 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/AXIOMS8020071",
"MAG": "2948527202",
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"license": null,
"status": null,
"url": null
}
|
The problem of complete controllability of a linear time-invariant singularly-perturbed system with multiple commensurate non-small delays in the slow state variables is considered. An approach to the time-scale separation of the original singularly-perturbed system by means of Chang-type non-degenerate transformation, generalized for the system with delay, is used. Sufficient conditions for complete controllability of the singularly-perturbed system with delay are obtained. The conditions do not depend on a singularity parameter and are valid for all its sufficiently small values. The conditions have a parametric rank form and are expressed in terms of the controllability conditions of two systems of a lower dimension than the original one: the degenerate system and the boundary layer system.
|
2022-12-09T02:15:08.573Z
|
122,728,322 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1364/JOSA.57.000645",
"MAG": "3016952847",
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},
"license": null,
"status": null,
"url": null
}
|
The index of refraction, n, of sodium films evaporated onto quartz substrates has been determined in the spectral region from 420 to 2000 A from interference patterns observed in the reflected beam and from the critical angle marking the onset of “total reflection.” The growth of an oxide layer on the surface of a film is shown not to alter appreciably the position of interference maxima and minima. The real part of the dielectric constant was consistent with a nearly-free-electron model. The effective volume–plasmon energy was found to be 5.69±0.06 eV, in agreement with the values determined from electron-energy-loss experiments.
|
2022-12-13T07:39:03.701Z
|
79,868,527 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1136/archdischild-2018-rcpch.108",
"MAG": "2789809578",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://adc.bmj.com/content/archdischild/103/Suppl_1/A45.2.full.pdf"
}
|
Within our deanery, monthly ‘Doctors in Training’ meetings are run at two District General Hospitals. These meetings are chaired by a selected trainee and attended by all junior doctors within the paediatric department. Before each meeting, members of the paediatric multidisciplinary team are invited to suggest topics for discussion and share information learnt from clinical governance, morbidity and mortality and child protection forums. During the meetings this information is shared with the trainees to keep everyone updated on key departmental policies and changes. Trainees are then given a safe forum to give feedback and discuss any positive aspects of working in the department, as well as areas for improvement. The trainees make suggestions for change based on these discussions. Minutes from the meeting are circulated to the junior doctors as well as to all the consultants in the department. The meetings have proved an invaluable link for information sharing between consultants and trainees in these paediatric departments. They are an opportunity for senior trainees to provide support to junior members of the team as well as developing their own management skills. 100% of consultants and doctors in training surveyed across the two hospitals agreed or strongly agreed that these meetings are a good idea and 100% felt that positive changes have been made in the departments as a result of these meetings. Trainees also reported that the meetings increased their awareness of departmental changes and that they were more likely to raise concerns at the meetings than directly to a consultant. Consultants have said, ‘I think these meetings are really important’, ‘they have been extremely useful’ and ‘they help to link team members.’ These meetings are a useful resource for doctors in training, consultants and for the paediatric department as a whole. Shift patterns limit face-to-face contact between team members so these meetings facilitate important communication within the department. They also provide the opportunity for trainees to guide service improvement. This initiative is highly recommended to other departments.
|
2022-12-15T01:00:10.891Z
|
95,484,844 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1021/MA052183L",
"MAG": "2041922255",
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},
"license": null,
"status": null,
"url": null
}
|
A highly stereocontrolled synthesis of five kinds of cis-poly[(arylenevinylene)-alt-(2,5-dioctyloxy-1,4-phenylenevinylene)]s has been accomplished by Suzuki−Miyaura-type polycondensation [arylene = p-phenylene (3af), m-phenylene (3bf), 4,4‘-biphenylene (3cf), 2,7-fluorenylene (3df), 9,9-dihexyl-2,7-fluorenylene (3ef)]. Reactions of (Z,Z)-bis(2-bromoethenyl)arenes (1a−e) with 2,5-dioctyloxybenzene-1,4-diboronic acid (2fx) in toluene in the presence of Pd(PPh3)4 catalyst, aqueous KOH base, and Bu4NBr as a phase-transfer catalyst at 80 °C for 24 h form 3af−ef with number-average molecular weight (Mn) of 5700−9500 in 77−99% yields. The stereoregularity of vinylene linkages in the polymer backbone has been found at least 95%. The starting monomers (1a−e) were prepared in almost geometrically pure forms (≥99% cis), either by ruthenium-catalyzed hydrosilylation of diethynylarenes followed by bromodesilylation of the resulting bis(2-bromoethenyl)arenes or by addition of bromine to arenediacrylic acids followed by...
|
2022-12-15T18:10:23.757Z
|
242,078,595 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/oso/9780190867850.003.0006",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Is there a diachronic rationality constraint on an agent’s intentions over time, one that favors stability of intention? I argue that there is reason to think that there is some such diachronic rationality constraint and that a plausible approach to this matter draws on our understanding of a planning agent’s self-governance over time. On natural assumptions, we normally have a reason of diachronic self-governance to conform to this constraint. This argues against what we can call brute shuffling in cases (of a sort discussed by John Broome) of continued incomparability over time. And we can embrace this norm without endorsing unacceptable forms of bootstrapping of normative reasons. In this way we extend the self-governance strategy for supporting basic norms of plan rationality from a focus on synchronic norms to this focus on a diachronic norm.
|
2022-12-23T08:11:17.208Z
|
141,813,084 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/0145482X0509900205",
"MAG": "331941321",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Persons with multiple disabilities often have limited functioning of their lower limbs and tend to spend large amounts of time sitting in a wheelchair (Lancioni, Oliva, & O’Reilly, 1997; Pfister et al., 2003). Efforts to enable some of these persons (that is, those who are in better overall physical condition) to make some use of their legs may involve the use of support walkers (Broadbent, Woollam, Major, & Stallard, 2000; Stallard, Major, & Farmer, 1996).
|
2022-12-30T00:45:10.339Z
|
104,376,495 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.29252/QUMS.12.8.30",
"MAG": "2902186383",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Received: 31 Jan, 2018 Accepted: 14 Mar, 2018 Abstract Background and Objectives: Humans live in the world of the waves and energies; the waves that are emitted from various sources and are harmful. One of the possible side effects of radioactive substances on the body is its effect on the amount of sperm production and fertility. In the present study, the effect of iodine 131, was investigated on the motility and number of sperm in male rat.
|
2022-07-10T05:03:52.950Z
|
73,601,710 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5831/HMJ.2010.32.1.053",
"MAG": "1968822865",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The concept of discrete curvature is a discretization of the curvature. Many literatures introduce discrete curvatures derived from arc length of circular arcs. We propose a new concept of discrete curvature of a polygon at each vertex, which is derived from area of fan shapes. We estimate the error of the discrete curvature and compare the discrete curvature with old one.
|
2022-07-19T23:43:29.393Z
|
109,460,144 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4271/902079",
"MAG": "1603890274",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Comparisons are discussed of computed and measured transient sprays from an air-assisted fuel injector. Although the measurements were extensive, they did not characterize fully the conditions at the nozzle exit which had to be obtained from a simple model of the flow within the injector. It is found that spray width, spray tip penetration, amount of spray found in the head vortex, and chamber fuel distribution are strong functions of the internal design of the fuel injector. Particularly important are the drop size distribution and the direction of the flow at the exit of the nozzle.
|
2022-09-12T10:43:26.537Z
|
236,618,843 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1096/FASEBJ.2021.35.S1.05444",
"MAG": "3171651862",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
During menopause, when endogenous estrogen levels are depleted, a rise in hypertension is observed in 75% of post‐menopausal women, suggesting there is a cardioprotective effect from estrogen. In previous studies, estrogen has been shown to effect hypothalamic paraventricular nuclei by its action to lessen the impact of a glutamate induced increase in blood pressure. These data, along with others, suggest that the cardioprotective effect of estrogen is regionally specific in the central nervous system. However, the mechanism(s) behind estrogen's attenuating effect on blood pressure have not been fully elucidated. We propose that estrogen regulates blood pressure in part, by inhibiting the actions of leptin. Leptin is an adipocyte‐derived peptide hormone. Activation of its signaling pathway within the central nervous system can alter blood pressure. Studies with injections of leptin in rodent's dorsomedial hypothalamus showed an increase in blood pressure, while antagonism of leptin receptors correlated with diminished blood pressure. Both results suggest that adjustment of leptin signaling in the dorsomedial hypothalamus is sufficient to alter blood pressure. In this study, we hypothesize that estrogen can block leptin receptor activation and downstream signaling events by increasing the expression of SOCS3 (suppressor of cytokine signaling 3), a negative modulator of leptin signaling. We tested our hypothesis by utilizing an in vitro system (i.e. GT1‐7 mouse hypothalamic neuronal cells) and an in vivo system (i.e. female C57B6 mice) that were treated with estradiol (100nM). Our data demonstrated that administering estrogen decreased the expression of leptin receptors in the hypothalamus and we proposed this occurred due to the increase in SOCS3 expression we observed when estradiol was administered. Taken together, these data suggest that estrogen can attenuate leptin's physiological response on blood pressure by increasing an inhibitor (i.e. SOCS3) of leptin's signaling.
|
2022-09-23T00:29:12.838Z
|
206,131,967 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1039/c8lc00293b",
"MAG": "2803598904",
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"status": null,
"url": null
}
|
We used microfluidic technology for preparing gas-liquid Janus emulsions; we firstly proposed a one-step preparation method of micro-grippers and then characterized the function of oriented and precise delivery behavior. Because of the enrichment of Fe3O4 nanoparticles, the micro-gripper can reach a speed of 1.5 mm s-1 driven by a magnetic field. The micro-gripper's body is made of a poly(N-isopropylacrylamide) hydrogel, a reversible temperature-responsive polymer. The thermo-sensitivity of hydrogels offers the function of grasping, to closely integrate with the target carried, ensuring the stability of the carrying process. The reversible variation of the hydrogel allows the micro-gripper to be reusable and have a long shelf life.
|
2022-12-04T18:58:06.430Z
|
36,402,432 |
{
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"DOI": "10.3109/02699052.2015.1075249",
"MAG": "2205869923",
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"url": null
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|
Abstract Objective: This study explored using the FIT as a measure of performance validity among veterans undergoing neuropsychological evaluation for mild traumatic brain injury (mTBI). Background: The Rey Fifteen-Item Memory Test (FIT) is a performance validity measure criticized for poor sensitivity. Methods: Two hundred and fifty-seven veterans completed the FIT and Wechsler Adult Intelligence Scale, Fourth Edition, Digit Span (DS); 109 of whom completed the Test of Memory Malingering (TOMM). FIT cut-offs of <9, <8 and stricter cut-offs were examined using DS and/or TOMM as criterion performance validity measures. Results: Only four participants scored below the standard cut score of 9 on the FIT. Among the 13 veterans failing both criterion tests, only two scored below 9 on the FIT. Regardless of which FIT cut-off was used, the FIT had poor diagnostic accuracy. Conclusion: Despite its popularity, the FIT is not supported as an appropriate measure of performance validity in veterans undergoing evaluation for possible mTBI. Therefore, inferences regarding neuropsychological data reliability with adequate statistical certainty require use of other measures of performance validity with greater sensitivity.
|
2022-12-12T08:28:17.198Z
|
95,896,381 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1080/00958970412331310527",
"MAG": "2011890750",
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},
"license": null,
"status": null,
"url": null
}
|
The reaction of ferrocenylacetylide compounds with Co2(CO)8 at room temperature affords four complexes bearing ferrocenyl units with approximately tetrahedral (μ-alkyne)dicobalt moieties [R–(C≡C) n –R′] [Co2(CO)6] n ′ [R = C5H5FeC5H4-C(CH3)2-C5H4FeC5H4, R′ = H, n = 1, n′ = 1 (1); R = C5H5FeC5H4 [ferrocenyl (Fc)], R′ = –CH=CHCl, n = 1, n′ = 1 (2); R = Fc, R′ = Fc, n = 2, n′ = 1 (3), n′ = 2 (4)]. The compounds were characterized by elemental analysis, IR, 1H(13C) NMR, MS and single-crystal X-ray diffraction analysis. The X-ray analyses show that coordination of the carbon–carbon triple bond and the dicobalt unit result in the formation of a Co2C2 tetrahedral core, and the substituents on the acetylenic units show a distortion from linearity that reflects this coordination mode.
|
2022-12-20T20:41:36.366Z
|
237,468,778 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/ijerph18178934",
"MAG": null,
"PubMedCentral": "8431133"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/1660-4601/18/17/8934/pdf"
}
|
Radionuclide contamination in terrestrial ecosystems has reached a dangerous level. The major artificial radionuclide present in the environment is cesium-137 (137-Cs). In humans, animals, and plants cesium ion (Cs+) behaves like potassium ion (K+) and it is localized mainly inside the cells. Pancreas and salivary glands secrete Cs in the intestine thus eliminating about 14% of ingested Cs with the feces, the remaining 86% is eliminated by the kidney with the urine. Ingested radiocesium can also cause in humans several cases of pancreatitis with secondary diabetes (type 3c), which are both on the rise in the world. The Author studied the correlation between the geographical map of mortality from pancreatic cancer (PC) and the map of nuclear plant accidents, atomic bomb testing, and radioactive fallout. The worldwide death rate of PC is increasing, but the exact cause is still not known. Published data in medical literature at World, European and Italian levels are reviewed and compared. 137-Cs, with a half-life of about 30 years, is still present in the environment for about 300–600 years. Autoradiographic studies in mice have shown that 137-Cs is concentrated in greater quantity in the pancreas, particularly in exocrine cells, where most malignant PCs originate. Some methods of radiocesium removal and PC prevention are also suggested. But there is still a persistent, and not entirely disinterested, the controversy between damage from high and low exposure to ionizing radiations.
|
2022-12-24T17:19:21.735Z
|
245,601,300 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.31470/10.31470/2706-7904-2021-16-23-31",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://psycholing-conference.com/index.php/conference/article/download/194/74"
}
|
The assessment of language proficiency from a psycholinguistics perspective has been a subject of considerable interest. Many literatures are devoted for the explanation of certain psychological phenomena related to first language acquisition and foreign language learning like language disorders/impairments, critical/sensitive period and language anxiety.
This paper sheds the light on foreign language anxiety, which is in my conviction the hardest problem that concerns the foreign language learner as well as the teacher. The origin of this conviction is that foreign language anxiety hampers learner performance on one hand, and on the other hand effects, negatively, the classroom language assessment which in turn sharpens learner’s anxiety more and more. There is a significant negative correlation between foreign language anxiety and classroom language assessment.
Three issues are to be tackled in this paper: (i) The implication of ‘anxiety’ as a psychological issue in foreign language learning, (ii) classroom language assessment in Tunisian schools and (iii) the relation between foreign language anxiety and classroom language assessment.
|
2022-12-27T16:57:48.811Z
|
165,373,712 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.33053/CIENTEC.V2I1.6968",
"MAG": "2897873518",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
O estudo de avaliacao de vulnerabilidade a contaminacao natural de aguas subterrâneas e um estudo que tem grande importância tanto para conhecimento das areas que estao sujeitas a contaminacao quanto para a saude dos usuarios desse recurso hidrico, principalmente em regioes que sao dependentes da agua subterrânea para abastecimento publico. O municipio de Ibiruba – RS, tem seu abastecimento publico de agua potavel 100% dependente de fontes provenientes de agua subterrânea, cuja a mesma e captada por moto bombas submersiveis instaladas dentro de pocos tubulares. Apos a analise dos dados disponiveis para executar o estudo, se optou pelo metodo GOD, o mesmo que e baseado em uma equacao levando em conta os dados de litologia, profundidade da agua e o grau de confinamento do aquifero que esta a agua subterrânea, metodo varia na escala de 0,0 a 1,0m sendo qualificado nas categorias de insignificante, baixo, medio, alto e extremo. Nesse estudo, o resultado de vulnerabilidade foi constatado como insignificante
|
2022-02-08T19:59:36.767Z
|
77,175,004 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1056/nejm-jw.NA35437",
"MAG": "2395183611",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Consuming large quantities of alcohol is linked to excess risk for atrial fibrillation (AF), but what about more moderate intake? To answer the
|
2022-02-11T05:47:34.563Z
|
207,592,691 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.11646/zootaxa.4170.2.5",
"MAG": "2523688780",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://biotaxa.org/Zootaxa/article/download/zootaxa.4170.2.5/23014"
}
|
New bivalve host records for four pinnotherid crabs of the Mexican Pacific are reported: Fabia subquadrata Dana, 1851, in Modiolus capax (Conrad, 1837); Opisthopus transversus Rathbun, 1893, in Tivela stultorum (Mawe, 1823); Pinnaxodes gigas (Green, 1992), in Pinna rugosa (Sowerby, 1835), and Panopea generosa Gould, 1850; and Tumidotheres margarita (Smith, 1870), in Nodipecten subnodosus (Sowerby, 1835). The southernmost distribution of F. subquadrata is extended to about 600 km along the west coast of the Baja California Peninsula; the distribution of P. gigas is extended outside the Gulf of California more than 1000 km north to San Quintín, on the west coast of Baja California; and the range of T. margarita is restricted on the west coast of Baja California to Scammon´s Lagoon, Baja California Sur and Playa Kino Viejo, Sonora in the central region of the Gulf of California, Mexico to Panama. Based on the new material, new information on taxonomy, ecology, and life history is provided for each of these species. Pinnotheres nudus Holmes, 1895 is restored as a valid species and is removed from its synonymy with O. transversus. An updated checklist with remarks on zoogeography for the 60 pinnotherid species, included in 23 genera, of the northeastern Pacific region (Alaska to the Mexican tropical Pacific) is given.
|
2022-12-16T11:20:21.627Z
|
166,115,074 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1086/TWC24042478",
"MAG": "2905459389",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Sodomy comes to embrace the scandal of surplus labor value because that value is dismissed as mere "reproduction" while not, in fact, being reproduced at its source. Uncom pensated, unrecognized, surplus labor value gives birth, via its sublimation as surplus buying power, to a monstrous, animated corpse, the phantasmagorically fetishized inor ganic commodity. In a culture where such births are consid ered "natural,' sodomy, which reveals the categorical scandal of their mixed composition, must be condemned as "unnatu ral," remaining but darkly interprétable, a love that dare not speak its name.
|
2022-02-08T19:38:53.394Z
|
249,676,063 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.11606/s1518-8787.2022056004315",
"MAG": null,
"PubMedCentral": "9239335"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.revistas.usp.br/rsp/article/download/199800/183891"
}
|
ABSTRACT OBJECTIVE Estimate the future number of hospitalizations from Covid-19 based on the number of diagnosed positive cases. METHOD Using the covid-19 Panel data recorded in Spain at the Red Nacional de Vigilancia Epidemiológica, Renave (Epidemiological Surveillance Network), a regression model with multiplicative structure is adjusted to explain and predict the number of hospitalizations from the lagged series of positive cases diagnosed from May 11, 2020 to September 20, 2021. The effect of the time elapsed since the vaccination program starting on the number of hospitalizations is reviewed. RESULTS Nine days is the number of lags in the positive cases series with greatest explanatory power on the number of hospitalizations. The variability of the number of hospitalizations explained by the model is high (adjusted R2: 96.6%). Before the vaccination program starting, the expected number of hospitalizations on day t was 20.2% of the positive cases on day t-9 raised to 0.906. After the vaccination program started, this percentage was reduced by 0.3% a day. Using the same model, we find that in the first pandemic wave the number of positive cases was more than six times that reported on official records. CONCLUSIONS Starting from the covid-19 cases detected up to a given date, the proposed model allows estimating the number of hospitalizations nine days in advance. Thus, it is a useful tool for forecasting the hospital pressure that health systems shall bear as a consequence of the disease.
|
2022-07-31T04:57:15.864Z
|
144,803,459 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/000271629300400202",
"MAG": "2045288595",
"PubMedCentral": null
},
"license": "CC0",
"status": "GREEN",
"url": "https://zenodo.org/record/2121586/files/article.pdf"
}
|
preface our inquiries into Anglo-Saxon laws and customs by a brief survey of the laws and customs of their most nearly allied continental kinsfolk. In the first recorded laws of the German tribes, we find that married women had a legal right to property of their own. Whether in the earliest times the German family was so purely patriarchal that the husband and father had absolute power over the lives and property of all members of his family, as in early Rome, or whether German women held a more exalted position than they have ever held since, and not only enjoyed the honors and perquisites of ’’ mother-right’’ but transmitted them solely in the female line, is a much-mooted question not in my purpose to discuss. It is certain that the earliest recorded German laws, written down at different periods from the fifth to the eighth centurn,! though varying greatly in their provisions, show married women in the possession of definite property rights, greater indeed, and more widely extended than women were to know again for centuries. In some limited customs, to be sure, the early regime of community of
|
2022-09-15T09:46:33.113Z
|
11,961,647 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/jemt.22227",
"MAG": "1833841165",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The yolk sac (YS) is the main source of embryonic nutrition during the period when the placenta has not yet formed. It is also responsible for hematopoiesis because the blood cells develop from it as part of the primitive embryonic circulation. The objective of this study was to characterize the transitional area between the YS and primitive gut using the techniques of light microscopy, transmission electron microscopy, and immunohistochemistry to detect populations of pluripotent cells by labeling with Oct4 antibody. In all investigated embryos, serial sections were made to permit the identification of this small, restricted area. We identified the YS connection with the primitive intestine and found that it is composed of many blood islands, which correspond to the vessels covered by vitelline and mesenchymal cells. We identified large numbers of hemangioblasts inside the vessels. The mesenchymal layer was thin and composed of elongated cells, and the vitelline endodermal membrane was composed of large, mono‐ or binucleated cells. The epithelium of the primitive intestine comprised stratified columnar cells and undifferentiated mesenchymal cells. The transitional area between the YS and the primitive intestine was very thin and composed of cells with irregular shapes, which formed a delicate lumen containing hemangioblasts. In the mesenchyme of the transitional area, there were a considerable number of small vessels containing hemangioblasts. Using Oct4 as a primary antibody, we identified positive cells in the metanephros, primordial gonad, and hepatic parenchyma as well as in YS cells, suggesting that these regions contain populations of pluripotent cells. Microsc. Res. Tech. 76:756–766, 2013. © 2013 Wiley Periodicals, Inc.
|
2022-10-09T05:59:30.252Z
|
23,196,449 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/IECON.2006.347636",
"MAG": "2540225721",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In order to manage batteries efficiently, it is necessary to know its state of charge. One of the physical parameters with information about the state of charge is the electrolyte density. This paper presents a plastic optic fibre sensor developed for measuring in real time the electrolyte density in lead-acid batteries. The multisensor consists of several optic fibre placed inside the battery at different positions in order to make measures at different heights. An electronic circuit was designed for controlling the light emitters and detectors in order to minimize the effects of the ambient light and temperature
|
2022-09-10T06:58:35.928Z
|
110,016,871 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5367/000000003322776343",
"MAG": "2073765248",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The CDIO initiative began as a joint endeavour involving four engineering schools in Sweden and the USA. The number of schools joining the project is increasing constantly. CDIO focuses on four activities – curriculum development, teaching and learning, workshops, and assessment projects – with a view to improving engineering education programmes by redesign and through the introduction of real engineering skills as well as hands-on experiences.
|
2022-09-21T17:02:16.170Z
|
153,709,119 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/ijau.12015",
"MAG": "1784619136",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Increasing concerns about company failures has given rise to the significant role of risk management in organizations. The Institute of Internal Auditors (IIA) has introduced a new framework which specifies that internal auditors' responsibilities include managing risks. This change from traditional to modern obligation may cause internal auditors to be uncertain regarding this function. This study investigates the effects of personal and organizational factors on role ambiguity amongst internal auditors in Malaysia. Survey questionnaires were distributed to 202 internal auditors. The results of this study provide insight into how individual and organizational factors impact the role ambiguity of internal auditors. The findings suggest that individuals with higher competency and autonomy experience lower levels of ambiguity. Furthermore, highly structured companies with in‐house internal audit create lower ambiguity for internal auditors in Malaysian companies.
|
2022-12-17T09:24:30.593Z
|
36,039,233 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3182/20140824-6-ZA-1003.00920",
"MAG": "2066116355",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract This paper presents a novel approach of Particulate Material (soot) measurement in a Diesel particulate filter using Electrical Capacitance Tomography. Modern Diesel Engines are equipped with Diesel Particulate Filters (DPF's), as well as on-board technologies to evaluate the status of DPF because complete knowledge of DPF soot loading is very critical for robust efficient operation of the engine exhaust after treatment system. In course of time, soot will be deposited inside the DPFs which tend to clog the filter and hence generate a back pressure in the exhaust system, negatively impacting the fuel efficiency. To remove the soot build-up, regeneration (active or passive) of the DPF must be done as an engine exhaust after treatment process at pre-determined time intervals. Since the regeneration process consume fuel, a robust and efficient operation based on accurate knowledge of the particulate matter deposit (or soot load) becomes essential in order to keep the fuel consumption at a minimum. In this paper, we propose a sensing method for a DPF that can accurately measure in-situ soot load using Electrical Capacitance Tomography (ECT). Simulation results show that the proposed method offers an effective way to accurately estimate the soot load in DPF. A hardware-in-loop bench has been built to further develop this sensing concept and experimentally verify the associated measurement technology. Preliminary experimental data is very promising. The proposed method is expected to have a profound impact in improving overall PM filtering efficiency (and thereby fuel efficiency), and durability of a Diesel Particulate Filter (DPF) through appropriate closed loop regeneration operation.
|
2022-06-05T04:53:11.862Z
|
23,801,300 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/POLYTR.2005.1596496",
"MAG": "2540242237",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Contactless smart cards are widely used in various applications, such as access control, transit fare payment systems, etc. In order to improve the performance and at the same time to reduce the production cost, research work on the application of new materials and the development of new processes never stops. In this study, the assembly process of contactless smart card using nonconductive adhesive film (NCF) was investigated and adjusted considering the poor performance of PET substrate used in the test in terms of its heat resistance. Pressure cooker test was then performed to further evaluate reliability performances of the card assemblies after being subjected to severe temperature and humidity conditions. The smart card assemblies underwent both mechanical and electrical characterizations during the assembly process and the reliability test. Examinations on surface morphologies and cross-sections by SEM and optical microscope were conducted to understand the failure mechanisms.
|
2022-09-07T04:40:26.902Z
|
153,942,231 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/9780470753514.CH7",
"MAG": "1982956894",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
L'A. essaie de demontrer que lhomme naturel dans le Discours sur l'inegalite de Rousseau est un etre humain issu de la conception du 18s. fondee sur le lien manquant entre les etres humains et les animaux.
|
2022-09-13T19:29:12.378Z
|
1,032,822 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3414/ME9105",
"MAG": "2095222188",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
OBJECTIVES
We developed an adaptive computer assistant for the supervision of diabetics' self-care, to support limiting illness and need for acute treatment, and improve health literacy. This assistant monitors self-care activities logged in the patient's electronic diary. Accordingly, it provides context-aware feedback. The objective was to evaluate whether older adults in general can make use of the computer assistant and to compare an adaptive computer assistant with a fixed one, concerning its usability and contribution to health literacy.
METHODS
We conducted a laboratory experiment in the Georgia Tech Aware Home wherein 28 older adults participated in a usability evaluation of the computer assistant, while engaged in scenarios reflecting normal and health-critical situations. We evaluated the assistant on effectiveness, efficiency, satisfaction, and educational value. Finally, we studied the moderating effects of the subjects' personal characteristics.
RESULTS
Logging self-care tasks and receiving feedback from the computer assistant enhanced the subjects' knowledge of diabetes. The adaptive assistant was more effective in dealing with normal and health-critical situations, and, generally, it led to more time efficiency. Subjects' personal characteristics had substantial effects on the effectiveness and efficiency of the two computer assistants.
CONCLUSIONS
Older adults were able to use the adaptive computer assistant. In addition, it had a positive effect on the development of health literacy. The assistant has the potential to support older diabetics' self care while maintaining quality of life.
|
2022-10-21T00:49:57.492Z
|
28,773,808 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1089/END.2006.0156",
"MAG": "2015125409",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
PURPOSE
We investigated the effect of pelvicaliceal differences on stone clearance after extracorporeal shockwave lithotripsy (SWL) in patients with solitary upper-caliceal stones.
PATIENTS AND METHODS
The clinical records of patients with solitary upper-caliceal stones who underwent SWL between 1996 and 2004 were reviewed. After excluding patients with hydronephrosis, significant anatomic abnormalities, non-calcium stones, metabolic abnormalities, recurrent stone disease, multiple stones, and previous renal surgery, 42 patients with a mean stone size of 153.47 mm2 (range 20-896 mm2) were enrolled in this study. They were divided into three groups according to stone burden (group 1 < or =100 mm2, group 2,101 mm2-200 mm2, and group 3 >200 mm2). Upper-pole infundibulopelvic angle (IPA), infundibular length (IL), and infundibular width (IW) were measured from intravenous urograms.
RESULTS
Of the total, 29 patients (69%) were stone free after SWL treatment. The differences in the upperpole IPA, IL, and IW of stone-free patients and patients with residual stones were not statistically significant (P = 0.85, P = 0.89, and P = 0.37, respectively). Again, there were no statistically significant differences in terms of upper IPA, IW, and IL in comparing the three groups divided by initial stone size.
CONCLUSION
Upper-caliceal anatomy does not exert a significant impact on stone clearance after SWL for isolated upper-caliceal stones. To best of our knowledge, this is the first study to investigate the effects of pelvicaliceal anatomy on SWL treatment for upper-caliceal stones, so there is a need for further investigations to confirm our findings.
|
2022-12-19T17:00:55.244Z
|
7,789,690 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/TCAD.2007.893549",
"MAG": "2099061921",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper studies area-efficient arithmetic circuits to multiply a fixed-point input value selectively by one of several preset fixed-point constants. We present an algorithm that generates a class of solutions to this time-multiplexed multiple-constant multiplication problem by ldquofusingrdquo single-constant multiplication circuits for the required constants. Our evaluation compares our solution against a baseline implementation style that employs a full multiplier and a lookup table for the constants. The evaluation shows that we gain a significant area advantage, at the price of increased latency, for problem sizes (in terms of the number of constants) up to a threshold dependent on the bit-widths of the input and the constants. Our evaluation further shows that our solution is better suited for standard-cell application-specific integrated circuits than prior works on reconfigurable multiplier blocks.
|
2022-12-21T03:51:05.008Z
|
12,142,596 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/WICOM.2008.2559",
"MAG": "2169969523",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper focuses on the learning organization's knowledge energy movement from the angle of quantum- mechanical theory, with the application of literature methodology and analogy methodology. The following conclusions were reached. Learning organization's knowledge energy is the sum total of work done by learning force to transfer learning organization system through knowledge sharing and innovating; the learning force is the reason of knowledge field energy movement. Learning knowledge leads to the breakthrough of the boundary of learning organizational knowledge energy and the lifting of energy level. The knowledge resonant promotes the organizational knowledge energy accumulation.The knowledge energy kernel reaction has impact on the management ways of learning organization.
|
2022-01-24T19:16:52.269Z
|
218,304,364 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5445/DIVA/2015-477",
"MAG": "3008303070",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Die Vorlesung analysiert Konvergenztendenzen von Wissenschaftsjournalismus und institutioneller Wissenschaftskommunikation. Entlang normativer Funktionszuweisungen und etablierter Kriterien fur journalistische Qualitat werden anhand praktischer Beispiele des Projekts Medien-Doktor sowie eines BMBF-geforderten Forschungsprojekts Unterschiede und Gemeinsamkeiten diskutiert. Abschliesend werden Ansatzpunkte fur eine verbesserte Kompetenz der Offentlichkeit zur Beurteilung der Qualitat von Informationen im digitalen Medienzeitalter aufgezeigt.
|
2022-02-08T01:48:26.256Z
|
225,161,370 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1557/jmr.2020.257",
"MAG": "3092405592",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
<jats:p><jats:fig position="anchor"><jats:graphic xmlns:xlink="http://www.w3.org/1999/xlink" mime-subtype="png" mimetype="image" xlink:href="S0884291420002575_figAb.png" /></jats:fig></jats:p>
|
2022-02-08T00:15:46.253Z
|
62,667,527 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1155/S1463924694000155",
"MAG": "2116116933",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper addresses some serious issues about personnel morale, fears and hopes associated with and attributed to the laboratory robot. The introduction of the laboratory robot into the laboratory is examined from a managerial perspective. Human-rights and robot-rights issues are identified and addressed. Real world examples of how the integration of two high through-put robots affected the routine of a major industrial food laboratory are discussed.
|
2022-04-08T01:29:37.398Z
|
144,559,371 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1467-9523.1997.TB00051.X",
"MAG": "2025797643",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Le formalisme bureaucratique est largement considere parmi les fonctionnaires grecs comme le moyen ultime d'assurer la protection d'une instance publique contre les interferences extra-institutionnelles. Ce papier vise a remettre en question cette position en examinant la maniere dont certaines dispositions de la PAC ont ete mises en place au niveau regional et local. A partir de l'analyse des traitements institutionnels diversifies mis en œuvre par les bureaucrates en charge de la PAC, on peut conclure que le formalisme bureaucratique particulierement pousse mis en œuvre dans certaines regions ne parvient pas, en fait, a proteger la puissance publique. Bien plus, il provoque la mobilisation des reseaux sociaux extra-institutionnel environnants. Ainsi, les regions soumises au traitement bureaucratique le plus pousse sont aussi, en termes de regulation administrative, les regions les plus fragiles
|
2022-07-28T05:45:00.432Z
|
143,849,105 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3917/PSYT.183.0059",
"MAG": "1975307469",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
La Guilde rassemble des cliniciens qui partagent leur experience clinique avec les joueurs excessifs aux jeux video, notamment les MMORPG. A travers l’etude de deux cas cliniques rapportes par des membres de la Guilde exercant au Japon et au Bresil, nous presenterons les prises en charge proposees en dehors de nos frontieres. Cette etude comparative des pratiques revele l’influence des facteurs socioeconomiques et religieux en Asie. De plus, meme si le nombre d’adolescents presentant un usage problematique des jeux video augmente, l’addiction aux substances psychotropes reste a cet âge une priorite de sante publique, particulierement en Amerique du Sud.
|
2022-09-09T14:26:54.150Z
|
98,133,954 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/JLAC.199619961022",
"MAG": "2057148842",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Oxidation of the tricyclic sesquiterpene hydrocarbon italicene (1a) or its 10-epimer 1b (isolated previously from Helichrysum oil) with SeO2 yielded mixtures of italicene-5-one (3a), italicen-15-al (4a), italicen-5-ol (9a) and italicen-15-ol (10a) or their 10-epimers 3b, 4b, 9b, 10b, whereas commercial α-copaene (6) reacted only to give a mixture of α-copaen-15-al (7) and α-copaen-15-ol (8). Jones oxidation of the allyl alcohols 9a or 9b afforded the pure ketones 3a or 3b MnO2 oxidation of the alcohols 10a or 10b furnished the aldehydes 4a or 4b. – Surprisingly, the italicene epoxides 2a or 2b rearranged with diluted HCl to the italicene ethers (epoxyacorenes) 5a or 5b, which previously were isolated from Lantana and Helichrysum oil. – The odor of 3a, 3b, 4a, 4b and 5a was evaluated.
|
2022-09-13T04:00:18.149Z
|
86,595,262 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/gcbb.12235",
"MAG": "2104701974",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Climate stabilization scenarios emphasize the importance of land‐based mitigation to achieve ambitious mitigation goals. The stabilization scenarios informing the recent IPCC's Fifth Assessment Report suggest that bioenergy could contribute anywhere between 10 and 245 EJ to climate change mitigation in 2100. High deployment of bioenergy with low life cycle GHG emissions would enable ambitious climate stabilization futures and reduce demands on other sectors and options. Bioenergy with carbon capture and storage (BECCS) would even enable so‐called negative emissions, possibly in the order of magnitude of 50% of today's annual gross emissions. Here, I discuss key assumptions that differ between economic and ecological perspectives. I find that high future yield assumptions, plausible in stabilization scenarios, look less realistic when evaluated in biophysical metrics. Yield assumptions also determine the magnitude of counterfactual land carbon stock development and partially determine the potential of BECCS. High fertilizer input required for high yields would likely hasten ecosystem degradation. I conclude that land‐based mitigation strategies remain highly speculative; a constant iteration between synoptic integrated assessment models and more particularistic and fine‐grained approaches is a crucial precondition for capturing complex dynamics and biophysical constraints that are essential for comprehensive assessments.
|
2022-12-07T22:44:54.454Z
|
212,431,222 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.25077/aogj.2.1.1-9.2018",
"MAG": "2990794293",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "http://jurnalobgin.fk.unand.ac.id/index.php/JOE/article/download/71/65"
}
|
Amniotic fluid is a liquid that fills the amniotic cavity which has defense and nutritional functions in fetal development. Human aterm amniotic fluid can be an ideal alternative as a source of mesenchymal stem cells, originating from the neonate. Preclinical studies of second and third trimester amnion fluid cells confirmed the number of potential donors from this wasted material. In several studies, AF-MSCs express mesenchymal markers such as CD90, CD73 (SH3, SH), CD105 (SH2), CD29, CD166, CD49e, CD58 and CD44 (MHC class I). These cells also express HLA-ABC antigens, CD 34, CD 45 which are hematopoietic markers, and endothelial CD31 markers. There is no expression of CD10, CD11b, CD14, CD34, CD117, EMA and HLA-DR, DP, DQ antigens. Most of AF-MSCs have pluripotent properties which are characterized by the discovery of octamer binding protein 3/4 (Oct-3/4), transcription factors Nanog (Nanog), and stage-specific embryonic antigen 4 (SSEA-4) on RT-PCR examination. From this study, 8 million cells was isolated. These cells will be used for research on pelvic organ prolapse therapy by using AF-MSCs. AF-MSCs isolation totally takes 6 weeks. From 1 flask, 2 million of stem cells was obtained.
|
2022-12-10T21:43:15.220Z
|
145,282,314 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1590/S1413-73722003000300003",
"MAG": "2101877666",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This research was regarding family functioning and ways of dealing with low income family children from a public school in the city of Recife. The sample consisted of 100 people of both sexes (parents and children caretakers) from 25 to 55 years of age. The instrument used was the Genogram Interview and Family Drawing with Story Telling. The results show that there are many types of family arrangements for taking care of these children, being the most common, the nuclear one. As for the family functioning, the great majority follows the female leadership due to the fragile role played by the male figure, who is frequently associated to unemployment and addiction to drugs.
|
2022-12-12T23:34:36.465Z
|
25,637,753 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1042/CS0910551",
"MAG": "107676577",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
1. Primary biliary cirrhosis is a chronic cholestatic liver disease with an autoimmune aetiology. The classical histopathological lesion, of portal tract biliary epithelial cell damage, is accompanied by a T-cell-rich mononuclear cell infiltrate and upregulation of cell surface markers suggestive of local T-cell activation and cytokine release. This suggests that T-cell mediated mechanisms play an important role in tissue damage in primary biliary cirrhosis. 2. CD4+ T-cells specific for the E2 component of human pyruvate dehydrogenase complex (PDC-E2), a highly conserved enzyme which plays a critical role in intermediate metabolism, are present in the peripheral repertoire of the majority of patients with primary biliary cirrhosis. These cells are almost entirely absent from normal and chronic liver disease control subjects. The observations that peripheral blood PDC-E2-specific cells are most commonly seen in early stage disease, when active bile duct damage is occurring, and that PDC-E2- specific cells can be found in the portal tract infiltrate at times when this damage is occurring, suggest that these autoreactive cells may have a role to play in the aetiology of primary biliary cirrhosis. 3. T-cells specific for the whole PDC and its E1 component are seen in significant numbers of normal control subjects as well as patients with primary biliary cirrhosis. Retention of potentially autoreactive cells in the normal T-cell repertoire has been reported for a number of other autoantigens. 4. T-cell epitopes appear to be widely distributed throughout PDC-E2. This is in contrast to the B-cell epitopes which are highly restricted to the inner lipoyl binding domain of the protein.
|
2022-12-15T02:19:52.167Z
|
214,768,995 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/nph.16563",
"MAG": "3014913469",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://nph.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/nph.16563"
}
|
Over the past decade, tremendous progress has been made in plant pathology, broadening our understanding of how pathogens colonize their hosts. To manipulate host cell physiology and subvert plant immune responses, pathogens secrete an array of effector proteins. A co-evolutionary arms-race drives the pathogen to constantly reinvent its effector repertoire to undermine plant immunity. In turn, hosts develop novel immune receptors to maintain effector recognition and mount defences. Understanding how effectors promote disease, and how they are perceived by the plant's defence network, persist as major subjects in the study of plant-pathogen interactions. Here, we focus on recent advances (last ~2 years) in understanding structure/function relationships in effectors from bacteria and filamentous plant pathogens. Structure/function studies of bacterial effectors frequently uncover diverse catalytic activities, while structure-informed similarity searches have enabled cataloguing of filamentous pathogen effectors. We also suggest how such advances have informed the study of plant-pathogen interactions.
|
2022-12-15T10:14:16.865Z
|
8,436,642 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1074/mcp.M115.054288",
"MAG": "2239771388",
"PubMedCentral": "4824857"
},
"license": null,
"status": null,
"url": null
}
|
Defining intracellular protein concentration is critical in molecular systems biology. Although strategies for determining relative protein changes are available, defining robust absolute values in copies per cell has proven significantly more challenging. Here we present a reference data set quantifying over 1800 Saccharomyces cerevisiae proteins by direct means using protein-specific stable-isotope labeled internal standards and selected reaction monitoring (SRM) mass spectrometry, far exceeding any previous study. This was achieved by careful design of over 100 QconCAT recombinant proteins as standards, defining 1167 proteins in terms of copies per cell and upper limits on a further 668, with robust CVs routinely less than 20%. The selected reaction monitoring-derived proteome is compared with existing quantitative data sets, highlighting the disparities between methodologies. Coupled with a quantification of the transcriptome by RNA-seq taken from the same cells, these data support revised estimates of several fundamental molecular parameters: a total protein count of ∼100 million molecules-per-cell, a median of ∼1000 proteins-per-transcript, and a linear model of protein translation explaining 70% of the variance in translation rate. This work contributes a “gold-standard” reference yeast proteome (including 532 values based on high quality, dual peptide quantification) that can be widely used in systems models and for other comparative studies.
|
2022-12-17T11:23:33.300Z
|
37,240,959 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/IMOC.2011.6169350",
"MAG": "1988761655",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Numerical results for the performance of simple NRZ-DQPSK optical link is analyzed in reference to the impact of using semiconductor optical amplifiers. The induced phase-noise impacts on fiber propagation, showing small but not negligible power penalty for 10Gbps and 20Gbps links (respect. 0.04dB/km and 0.1dB/km plus 1dB (SOA);BER=10−9).
|
2022-12-19T20:44:58.810Z
|
61,096,989 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/IECON.1992.254464",
"MAG": "1532105431",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Detection of incipient faults caused by gradual deterioration of the variables in chemical processes is considered. The authors focus on the issue of optimizing a set of learning data to obtain efficient diagnosis of multiple faults of different degrees in chemical processes. This problem may be considered as one of recognition of large patterns. By using the ability of neural networks to perform generalization, all patterns can be recognized by a small network, which has been trained by optimal learning data of single faults. A set of optimal learning data was found by which an optimal network can be easily trained to perform generalization. By using the optimal network trained by the optimal learning data, a diagnostic system for incipient faults can be constructed.<<ETX>>
|
2022-12-19T13:12:22.745Z
|
38,837,389 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1600-0714.1983.TB00354.X",
"MAG": "1578703987",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Lipid-soluble radiographic contrast medium was infused retrogradely through the main excretory duct of the rat submandibular gland until ductal and slight parenchymal filling or heavy parenchymal filling was achieved, as determined by the developing intraglandular pressure. The glandular tissue was fixed by vascular perfusion at different times following infusion, and examined by light and electron microscopy. Dilation of the intralobular ducts and scalloping of the luminal border were pronounced after both degrees of filling. Widening of the acinar lumina and intercellular canaliculi occurred early. Masses of fused secretory granules were commonly seen in the cytoplasm of the acinar cells and formation of vacuoles occurred frequently. In some acinar cells, densely packed granules filled the major part of the cytoplasm. Large lysosomes and autophagic vacuoles, frequently present in the various parenchymal cells, often contained apparent contrast medium. In addition, widening of the intercellular spaces between parenchymal cells was seen, particularly in the acini and intercalated ducts. An inflammatory cell-infiltrate, primarily comprised of polymorphonuclear leukocytes, was particularly prominent at 20 h and 30 h after infusion. The changes were generally more pronounced and persisted for a longer time in glands subject to heavy parenchymal filling. Large cyst-like spaces surrounded by inflammatory cells were seen in the lobules and in the interlobular connective tissue of these glands. At later times, areas containing apparent contrast medium surrounded by macrophages, were frequently observed in the connective-tissue stroma. Atrophy of the parenchymal cells was seen later, after heavy parenchymal filling, and a proliferation of the connective tissue had occurred. The changes were most probably caused by the elevated intraglandular pressure induced during infusion, and the subsequent cell damage and inflammatory reaction. A foreign body reaction, induced by the retained lipid-soluble contrast medium, was probably partly responsible for the morphological alterations observed, following infusion.
|
2022-02-12T05:43:30.656Z
|
38,664,134 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1684/ejd.2012.1895",
"MAG": "1670827974",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
ejd.2012.1895 Auteur(s) : Yuta Kurashige1 kurasige@tokyo-med.ac.jp, Tokuya Minemura1, Tetsuo Nagatani1, Hiroshi Koga2, Takashi Hashimoto2 1 Department of Dermatology Hachioji Medical Center Tokyo Medical University 1163 Tatemachi, Hachioji-shi, Tokyo 193-0998, Japan 2 Department of Dermatology, Kurume University, Kurume, Japan Bullous pemphigoid (BP) and cicatrical pemphigoid (CP) are autoimmune blistering diseases that produce immunoglobulin (Ig) G autoantibodies against antigens located in the [...]
|
2022-02-12T06:24:04.224Z
|
187,271,623 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.12783/DTSSEHS/ICSSM2018/26982",
"MAG": "2911836567",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
At present, the demand for elderly services in China is increasing and diversified, however, there are serious shortcomings in the supply side of the elderly service in China. The old-age service industry in China is still in the early stage of development, the pension industry has not yet formed, the problem of inadequate supply of pension services and products is very prominent, the limited service mode, ignoring the old-age pension service in rural areas, there is a shortage of care for elderly people with disabilities and dementia, the talent for the old-age service is scarce. To solve the shortcomings of the current supply side of China's aged care service, in response to the coming of aging, we should take the needs of the elderly as the purpose to promote the supply side reform of the pension services. By analyzing the basic connotation, supply and demand relationship and structure type of the pension service supply, summarize the characteristics of population aging in the new era, to explore the countermeasures and suggestions on the supply-side structural reform of pension service.
|
2022-02-08T10:44:15.610Z
|
67,775,940 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.26483/ijarcs.v7i6.2761",
"MAG": "2891689694",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Vehicular Ad hoc Network (VANET) are the promising approach to provide safety and other beneficial applications to the drivers as well as passengers. It is recognized as an essential component of intelligent transport system. In this paper, we have discussed about some security attacks in vehicular Ad hoc Network. We have also discussed about some solutions that can be implemented against these attacks. Life saving characteristics of VANET has attracted the industry and researchers. In VANET vehicles are nodes so they have no fixed infrastructure. It serves safe and non safe application in wireless medium which makes it venerable to several attacks. Keywords: VANET characteristics, Overview of attacks, Solutions.
|
2022-02-11T12:41:29.592Z
|
201,995,946 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1182/BLOOD.V128.22.4185.4185",
"MAG": "2969129761",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Introduction. Copanlisib is a pan class-I PI3K inhibitor (i) with preferred activity towards PI3Kα and PI3Kδ that is currently in clinical development as single agent and in combination for patients with non-Hodgkin lymphomas. Here, we performed a screening of copanlisib as single agent and in combination with 15 other anti-cancer agents on a panel of 17 lymphoma cell lines derived from mantle cell lymphoma (MCL), marginal zone lymphoma (MZL) and chronic lymphocytic leukemia (CLL). Methods. Cell lines derived from MCL (Jeko1, Rec1, JVM2, Granta519, Maver1, Mino1, SP-49, SP-53, UPN1, Z138), MZL (Karpas1718, VL51, SSK41, ESKOL, HAIR-M, HC-1) and CLL (MEC1) were exposed to increasing doses of copanlisib alone and in combination with increasing doses of other compounds using the fixed ratio set-up. Tested compounds were approved as well as experimental inhibitors of key regulatory pathways: e.g. anti-CD20 monoclonal antibody rituximab, BTK-i ibrutinib, CDK-i roniciclib, DNA damage agent bendamustine, HDAC-i panobinostat, HDAC1/2-i romidepsin, immunomodulatory lenalidomide, JAK1/2-i ruxolitinib, MALT-i MI2, proteasome-i bortezomib. Synergy was assessed with Chou-Talalay combination index (CI): synergism ( 1.1). Gene expression profiling (GEP) was done using the Illumina-HumanHT-12 Expression-BeadChips and GSEA (FDR Results. Copanlisib showed anti-tumor activity in the vast majority of cell lines with a median IC50 of 22nM (95%C.I.; 15-98) across all the cell lines, 36nM (6-175) in MZL, 22nM (95%C.I., 3-103) in MCL, 23nM in the CLL MEC1. Among all cell lines, the most active other compounds were bortezomib (IC50 5nM; 95%C.I., 5-7), romidepsin (34nM, 2-94), roniciclib (23nM, 18-29), panobinostat (161nM, 11-1263), MI2 (490nM; 224-1000) with remaining having median IC50s >500nM. Among these the only showing higher activity in one histotype was panobinostat, more active in MCL than MZL (IC50 17 vs 557nM, P 0.04). As pattern of activity across the cell lines, copanlisib was positively correlated with ibrutinib (R 0.58, P 0.001) and negatively with ruxolitinib (R -0.55, P 0.021). When copanlisib-containing combinations were tested in the 17 cell lines, different ones frequently appeared synergistic or additive: for example copanlisib plus MI2, 88% (15); plus ibrutinib, 82% (14); plus AKT-i or panobinostat, 76% (13); plus lenalidomide or BET-i, 71% (12); plus rituximab, 65% (11); plus romidepsin, 59% (10); plus roniciclib, 53% (9); plus bortezomib, 47% (8); plus bendamustine, 35% (6); plus ruxolitinib, 12% (2). For combinations with the most promising effect, baseline GEP identified gene-sets associated with different sensitivity to these combinations. High expression of genes involved in interferon signaling, oxidative phosphorylation, fatty acid metabolism, apoptosis, PI3K/AKT/mTOR and IL6/JAK/STAT signaling and low expression of genes involved in cell cycle were associated with synergism to copanlisib combinations with several compounds. Interestingly, largely the opposite was observed for the combination with others, with better synergy in cells with high expression of E2F/MYC targets and genes involved in cell cycle and low expression of transcripts involved in interferon PI3K/AKT/mTOR and IL6/JAK/STAT signaling. Conclusion. Copanlisib was active in cell lines derived from MCL, MZL and CLL. Combinations of copanlisib with a variety of additional anti-cancer compounds were synergistic and/or additive when combined in different cell lines. The combinations of the synergy profiles in the cell lines tested and the specific GEP features might predict lymphomas that could benefit from these regimens. Disclosures Jourdan:Bayer Pharma AG: Employment. Berthold:Bayer Pharma AG: Employment. Rossi:Gilead: Honoraria, Research Funding; Abbvie: Honoraria; Janseen: Honoraria. Lange:Bayer Pharma AG: Employment. Politz:Bayer Pharma AG: Employment.
|
2022-07-29T09:47:47.401Z
|
22,630,459 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1093/jjco/hyx104",
"MAG": "2759986054",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://doi.org/10.1093/jjco/hyx104"
}
|
The precise assessment of both tumor factor and the liver function is of a crucial value the surgical treatment with the greatest guarantee of hepatocellular carcinoma (HCC), as the balance between the operative procedure and the remnant liver function is the most important concern in patients with chronic liver disease. The mortality rate in liver resection has decreased significantly worldwide, according to various surgical criteria for liver resection. Among countries where HCC is prevalent Japan is a leading country in doing liver resection. The Japanese evidence-based guidelines for the surgical treatment for HCC were generated in 2005, and the third revised version is now available. A strict evaluation policy for surgical indications and management based on such evidence helps to minimize the mortality rate in these patients. Herein, we report a series of unique approaches to the perioperative management of liver resection based on the available evidence with the goal of achieving 'no mortality' in liver resection for HCC.
|
2022-10-30T15:53:27.766Z
|
235,528,990 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.18231/J.IJPCA.2021.006",
"MAG": "3159361624",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The Athlete Biological Passport (ABP) is an indirect approach which provides a complementary and more sophisticated strategy to traditional analytical testing in an effort to scientifically gather evidence of possible doping in sport. The ABP is one tool in a kit of intelligent anti-doping practices meant to deter and detect the use of prohibited substances in sport. In 2013, the WADA Athlete Biological Passport Guidelines introduced a second module, the Steroidal Module, which became operational since January 1, 2014. The Steroidal Module monitors an athlete’s steroidal variables over time that may be indicative of steroid abuse. This paper summarized the details of samples requested for confirmation on GC/C/IRMS in year 2015 & 2016 to understand the pattern of generation of Atypical Passport Finding Confirmation Procedure Request (ATPF-CPR). Interestingly, out of total 26 cases of ATPF-CPR received by NDTL, three samples with normal steroid profile showed exogenous origin of endogenous steroids on GC/C/IRMS analysis,
which proves the effectiveness of Steroidal Module. In this context, monitoring of steroid passport through steroidal module represents the new paradigm in detection of exogenous origin of endogenous steroids.
Keywords: ABP, Steroid Profile, SSPCPR, ATPFCPR, Endogenous, Exogenous.
|
2022-11-18T00:58:51.098Z
|
58,620,377 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1183/16000617.0079-2018",
"MAG": "2903777014",
"PubMedCentral": "9488583"
},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://err.ersjournals.com/content/errev/27/150/180079.full.pdf"
}
|
It is well known that lung cancer can manifest itself in imaging as solid and subsolid nodules or masses. However, in this era of increased computed tomography use another morphological computed tomography appearance of lung cancer is increasingly being recognised, presenting as a malignancy in relation to cystic airspaces. Despite the fact that it seems to be a relatively common finding in daily practice, literature on this entity is scarce and presumably the overall awareness is limited. This can lead to misinterpretation and delay in diagnosis and, therefore, increased awareness is urgently needed. This review aims to illustrate the imaging appearances of cyst-related primary lung malignancies, demonstrate its mimickers and potential pitfalls, and discuss the clinical implications based on the available literature and our own experience in four different hospitals. Primary lung cancer can present as cystic airspace with an associated solid component, and seems to be a relatively common imaging phenotype of (early) lung cancer. This morphology is often not recognised and misinterpreted, leading to diagnostic delay. http://ow.ly/hZrJ30mIVX1
|
2022-11-25T01:08:58.065Z
|
136,416,454 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICSD.1995.522940",
"MAG": "1815960082",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
There are several polymers being used as extruded insulation in high-voltage power cables from 5 kV up to 500 kV. They include low density polyethylene (LDPE), crosslinked polyethylene (XLPE), tree-retardant crosslinked polyethylene (TRXLPE) and different formulations of ethylene propylene rubber (EPR). The ageing mechanisms of extruded insulations operating under wet (usually for medium-voltage cables) and dry conditions (for high-voltage cables) have been discussed. Diagnostic techniques, both destructive and non-destructive, have also been discussed using the possible ageing mechanisms as a basis.
|
2022-12-09T20:54:07.602Z
|
128,687,856 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1306/C1EA59DB-16C9-11D7-8645000102C1865D",
"MAG": "2042669308",
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},
"license": null,
"status": null,
"url": null
}
|
Time-parallel limestone beds of the well-known Kansas section have been traced westward in an attempt to determine their total geographic extent, their origin, and their utility in precise regional correlation. The entire sequence of marker beds extends from Canon City, Colorado, to Springer, New Mexico. Certain groups of these markers are traceable southward to White Oaks, New Mexico, northward to the Black Hills, and westward to the northern San Juan basin. The most widespread limestone beds were deposited across areas no smaller than 388,000 sq km (150,000 sq mi). Individual beds are identified positively by position in sequence, relation to adjacent bentonite seams, lithology, and fossils. Each bed is thoroughly bioturbated, and the thickness, fossil content, and fiel characteristics are remarkably uniform for great distances. Dominant mineralogy is calcite; quartz and pyrite are the only consistent accessory minerals. The limestones are micritic to microsparitic wackestones and, uncommonly, packstones. Principal allochems are planktonic forams, inoceramid bivalve fragments and prisms, calcispheres, and oyster fragments. Fecal pellets are scarce west of the Rocky Mountain front but common in Great Plains sections. Limestone bed contacts are mostly gradational with adjacent shaly strata, and evidence for hardgrounds is lacking. Limestone beds of the Bridge Creek Member reflect offshore shelf deposition during the late Cenomanian-early Turonian transgressional maximum of the Western Interior sea. Relative proportions of pelagic versus benthonic allochems confirm that limestone beds represent slow deposition caused by reduced detrital influx. Deposition occurred on a nearly planar surface, with local highs marked by areas of condensed sequences. End_of_Article - Last_Page 464------------
|
2022-02-09T15:27:53.853Z
|
165,108,346 |
{
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"ArXiv": null,
"DOI": "10.1177/1687814019846766",
"MAG": "2944262998",
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},
"license": "CCBY",
"status": "GOLD",
"url": "https://journals.sagepub.com/doi/pdf/10.1177/1687814019846766"
}
|
This study improved the roundness error of the side portion of a lead wire produced by rolling operations. In the conventional method, the side portion is cut after rolling. As an improvement, a side roller was designed for use after flat rolling to directly form the side portion of the lead wire to reduce the roundness error. A rolling analysis of lead wires was performed using LS-DYNA, which is a simulation program capable of analyzing the dynamic behavior of the material. Finite element modeling of the lead wire was carried out, and the change of the cross section was observed after the wire rolling process. The shape of the side roller was optimized to reduce the roundness error. The angle of the side roller, the installation position, and the shape radius were selected as the design variables. PIAnO (Process Integration, Automation, and Optimization), a commercial PIDO (Process Integration and Design Optimization) tool, was used for the optimum design of the side roller, and the results confirmed that the roundness error was reduced.
|
2022-02-08T20:06:18.719Z
|
95,920,209 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1097/00010694-198010000-00005",
"MAG": "2013557870",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In a stand of Fagus silvatica in the Solling highlands, Federal Republic of Germany, we followed the effect of acid precipitation on chemical soil state and the ion fluxes in the ecosystem between 1966 and 1979. As indicated by increasing aluminum concentration in the soil solution and an increase in organic matter storage in the forest floor, for example, the soil shifted during the measuring period from one state toward another one. During this transition, the acid precipitation has induced soil internal H+ ion production, partly by accumulation of organic matter poor in nitrogen, and partly by a probable change in the type of nitrogen nutrition. Two-thirds of the H+ ion buffering is due to the dissolution of polymeric hydroxoaluminum, resulting in the formation of solid AlOHSO4 and the leaching of Al ions. There are indications that the Al concentration in soil solution reaches toxic levels for the stand. The findings may have serious consequences for forestry in central Europe.
|
2022-12-22T16:29:14.506Z
|
223,723,000 |
{
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"DOI": "10.29764/XBDSX.200710.0006",
"MAG": "2554812858",
"PubMedCentral": null
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"license": null,
"status": null,
"url": null
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|
《四庫全書總目提要》中提到，《漢書》在魏晉南北朝時期有一段今古本真爲爭議的討論，主因是南朝梁時，鄱陽嗣王範在偶然間得到了班固所撰真本漢書，並將其獻給東宮，東宮太子讓劉之遴、張纉等人考訂該書與今本漢書之間的異同，遂產生了今古本漢書真爲的爭議問題。劉之遴在考訂過程中提出了今本漢書數十項與古本相異之處，而《四庫全書總目提要》針對這些相異處提出了辯駁，認為劉之遴所提出的異狀實際上是有問題的。 劉之遴認為今古本漢書的第一點不同在於，有無書寫年月日字等，認為古本有而今本無。第二個問題則是敘傳名稱的不同，認為古本將傳稱為中篇，而今本則稱敘傳。第三點與敘傳的內容有關，認為今本敘傳有記載其父班彪的事蹟，而古本則另有班彪傳。第四點指出兩個版本間編排上的相異處，即是今本，紀、表、志、列傳不依次合成卷，而古本則依次相合成三十八卷。第五點與第六點都與篇目的安排順序不同有關。第七個異處在於文句上的不同。第八個異處則是提出今本有缺卷的可能。《四庫全書總目提要》在此反駁劉之遴的論點，提出魏晉南北朝時期，作僞書的風氣相當盛行，劉之遴所拿到的那個版本應該是爲的，並且以考據學的角度來看劉之遴的論點，認為他的考據方式有問題。
|
2022-01-24T18:51:18.740Z
|
80,355,114 |
{
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"DOI": "10.1097/BCO.0000000000000560",
"MAG": "2760876580",
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"license": null,
"status": null,
"url": null
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|
A number of intellectual authorities have over the years spoken about the decline and eventual collapse of civilizations and ideas. Among them are Oswald Spengler and Arnold Toynbee whose reputations as giants in the History/Philosophy area have not diminished with time. Just a few decades ago James Burnham wrote The Suicide of the West, an insightful and well-documented book, worthy of study and attention. It is possible that these people may prove to be wrong in their predictions and analyses. However, it would be foolish to ignore their words and the possibility that supporting evidence may prove them correct. To deny the signs of decline may be blindness of the worst kind. The orthopaedic discipline seems to also be demonstrating symptoms of decline. I express my pessimistic views based on experience and study of my profession over 6 decades devoted to an academic career, heavily intertwined with medical and political administrative components. Economic profit, ethical misconduct, subspecialization, orthopaedic treatment guidelines, education, research, and publication all play a role in this decline. Economic profit: A factor likely to explain the genesis of my perceived decline of the orthopaedic profession is the role economic profit has played. To many, medicine is no longer an altruistic profession but a business, with many becoming product vendors. Implant manufacturing companies have assisted orthopaedists in advancing the progress we witness today, and without such cooperation, the surgical treatment of many musculoskeletal conditions would be significantly retarded. Progress is desirable; but it comes at a price, and not every new major change is progress. History is replete with disastrous consequences from the implementation of “healthy” changes. One needs only to look at our discipline and the progress made over the last few decades. What were the true meaningful advances? We claim newer techniques and appliances to treat conditions, such as osteoarthritis and rheumatoid arthritis, but have we been able to treat such pathological conditions based on new scientifically acquired knowledge? Have we unequivocally proved that fracture healing is expedited by rigid immobilization with plates of different designs and metals? When we look impartially at the status of orthopaedics in poor regions of the world, we must conclude that ours and other rich countries have done very little to assuage their dilemmas. Mostly we have simply tried to encourage them to use our advanced technologies. A few organizations, such as the World Orthopaedic Concerns, dedicate resources and time to balance the inferior conditions in poor countries, but the obstacles they encounter limit their success. At a different level, what has our profession done to reduce the cost of orthopaedic care in our country and throughout the underdeveloped world? Nothing or very little, is probably the correct answer. Improved technology has made it easier to diagnose and treat many pathological conditions, but the cost involved is high; it is a cost poor countries cannot afford. Moral and ethical misconduct: One of the most important determinants in the decline of our profession, in my opinion, is the moral and ethical misconduct committed by some members of our profession. At a time when ethical infractions are made public with increasing frequency, we seem to be responding not by acknowledging our official disapproval and plans to correct the problem, but by suggesting the issue is not important. Nothing speaks more to this than the recent action by the American Academy of Orthopaedics to discontinue its Ethics Committee as a separate body and to include it as part of a multipurpose one, a move likely to be regretted. Subspecialization: The enthusiasm with subspecialization in orthopaedics has reached an unprecedented level and is playing a role in the decline of our profession. Despite the fact that there are good arguments to justify subspecialization, an exaggerated number of subspecialties may be eroding our profession. If the trend continuous, every orthopaedist in the United States will be a subspecialist, a disturbing scenario because in many small communities, there are not enough patients with conditions requiring subspecialized care. This will leave a healthcare void in these regions that other physicians and allied health practitioners will fill. Currently several medical and paramedical disciplines are proposing major changes and are having some success. The options to solving this are numerous, but two choices are likely to surface in the future. One is the surrendering to other medical and paramedical disciplines the care of a number of orthopaedic territories. Chiropractors, osteopaths, and others will step into the arena and claim that their competency is adequate. They will also claim that costs will be reduced because referrals to other subspecialized surgeons will be less by comparison. The other choice is a socialized system, where every orthopaedist is salaried. It is said that this system would erase the current reluctance to practice in smaller communities. Financial Disclosure: The author reports no conflicts of interest. Correspondence to Augusto Sarmiento, MD, Orthopaedics and Rehabilitation, University of Miami, 200 Harbor Walk Drive, Suite 335, Punta Gorda, FL 33950 Tel: +941-655-8616; fax: +941-655-8616; e-mail: asarm@bellsouth.net. 1940-7041 Copyright © 2017 Wolters Kluwer Health, Inc. All rights reserved. E D I T O R I A L
|
2022-02-11T03:13:53.778Z
|
142,620,730 |
{
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"ArXiv": null,
"DOI": "10.15848/HH.V0I5.199",
"MAG": "1596224578",
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},
"license": null,
"status": null,
"url": null
}
|
Written version of Carlos Barros’ conference, held during the 3rd International Congress “Historiaa Debate” (Santiago de Compostela, 14th-18th July 2004). The conference is about the international development of the Historia a Debate’s network, whose roots are in 1993(1st Congress) and 1999 (in Internet), when the digital community was founded. The Historia a Debate network is a global historiographical trend, resulted from a Latin, European and American initiative, compared to the related official experience of the International Comission of Historical Sciences, at one side, and also newly initiatives by the north-american historiography, on the other.
|
2022-03-11T06:31:16.457Z
|
79,807,479 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1056/JD199906010000006",
"MAG": "2625735988",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The pulse dye laser (PDL) improves established hypertrophic scars. In this uncontrolled, industry-sponsored study, 106 patients with 171 postoperative scars underwent 585-nm PDL treatments starting two to three weeks after surgery and continuing at three to four week intervals for three to six treatments until satisfactory scar flattening and lightening had been achieved.
Initial …
|
2022-02-11T03:42:02.263Z
|
230,522,686 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.31341/jios.44.2.3",
"MAG": "3112503870",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://hrcak.srce.hr/file/360249"
}
|
Competencies represent a dynamic combination of cognitive and metacognitive skills, knowledge and understanding, interpersonal and practical skills, and ethical values. Since there are many entities, as well as many activities between entities, according to system theory, the whole system belongs to complex systems. The paper develops a conceptual and computational model of interpersonal competences for the process of optimization and methodology design, using simulation modeling. The developed model enables: faster data collection, more accurate results, avoiding human error in data entry and processing, survey time can be measured and more easily restricted, NMAR (Not Missing at Random) data is avoided and socially desirable responses are more easily avoided.
|
2022-08-20T11:19:05.986Z
|
22,240,333 |
{
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"ArXiv": null,
"DOI": "10.1520/JFS12294J",
"MAG": "1602879937",
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},
"license": null,
"status": null,
"url": null
}
|
Pedophiles constitute a heterogeneous group of sex offenders. Direct physiological assessment of sexual arousal has significantly increased our diagnostic skill and capability of monitoring treatment response. Erectile response studies have indicated that the majority of pedophiles and incest offenders show arousal to other paraphilias and frequently to appropriate adult sexual stimuli. Many sexual offenders deny or minimize their problem during initial interviews, but when confronted with laboratory results indicating deviant sexual arousal, they often acknowledge and elaborate on the paraphilia(s). Complete data and diagnoses are crucial in integrating treatment in the cognitive-behavioral paradigm.
|
2022-09-11T09:52:13.330Z
|
155,537,724 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2469/faj.v72.n2.3",
"MAG": "2259826886",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "http://www.cfapubs.org/doi/pdf/10.2469/faj.v72.n2.3"
}
|
An immediate annuity is precisely the sum of two parts. One is a deferred annuity commencing at a specified date, with no death benefit before that date. The remainder, before the deferred annuity commences, is a reverse whole life insurance policy with limited premiums. That reverse policy is effectively one underwritten by the annuitant, with the insurance company as beneficiary—a policy that benefits few retirees. However, the deferred annuity (called “longevity insurance” in the literature) is a valuable component of a retirement portfolio that supplements components that focus on safety and growth. The summary was prepared by Jennie I. Sanders, CFA, New York City. What’s Inside? Longevity assumptions are a critical component of financial planning. Many retirees have sufficient resources to allocate on the basis of the goals of safety, growth, and longevity. The probability of living past one’s life expectancy is relatively low, but to do so means outliving one’s resources, resulting in a high financial impact. Longevity insurance should be akin to fire insurance in that the cost to insure should be low, paying off only if the risk occurs and paying nothing if the risk does not materialize. Obtaining longevity insurance through an immediate annuity results in unnecessary costs. How Is This Research Useful to Practitioners? Those retiring in the next decade are increasingly concerned about outliving their savings, and practitioners and researchers have been seeking solutions to this uncertainty. Prior research—for example, Yaari (Review of Economic Studies 1965) and Ameriks, Veres, and Warshawsky (Journal of Financial Planning 2001)—has focused on how immediate annuities provide some certainty by means of a lifetime income. Dus, Maurer, and Mitchell (Financial Services Review 2005) found a benefit in having a deferred annuity that initiates if the retiree lives beyond a certain advanced age. Milevsky and Robinson (Financial Analysts Journal 2005) suggested that retirees should plan their spending similar to how insurance companies consider expected payments, mortality tables, and investment returns in achieving a high probability of adequate reserves. Scott (Financial Analysts Journal 2008) discussed the “spending improvement quotient” (Q), arguing that an immediate annuity is more economical than saving all one’s money for an expected drawdown. He suggested incorporating a deferred annuity as a more agreeable solution, which pays off at some future date only if the purchaser is still alive. In an earlier paper (Rotman International Journal of Pension Management 2011), the author found that after age 75, the risk of longevity exceeds the risk of being invested in 100% equities in terms of the relative financial impact (supporting the usefulness of annuities). In this article, the author points out that immediate annuities remain underutilized by most retirees despite the research supporting their benefits. He makes a plea to insurance companies to consider writing longevity insurance and explores immediate annuities as the next-best solution. He indicates that an immediate annuity is essentially two products: a reverse whole life insurance policy and a deferred annuity. He argues that a reverse whole life policy benefits the insurance company far more than the immediate annuitant, who is essentially underwriting the policy on the annuitant’s own life. More retirees may see the value of a deferred annuity, which does not have the cost associated with a reverse whole life policy. How Did the Author Conduct This Research? To illustrate the components of an immediate annuity, the author considers a 68-year-old male purchaser, assuming longevity according to Canadian annuitant tables and a contractual fixed rate of return of 2.5% a year. The mortality table suggests an equal split between 68-year-olds dying before and after the age of 86. Payments are made by the insurance company once a year starting immediately, with a high probability of adequate reserves (ignoring spousal features). The immediate annuity cost of providing $1 a year for life to the 68-year-old male is a lump sum of $14.78. It costs $2.53 today if the purchaser wants to forgo annual payments until age 85 and buy a longevity annuity that pays only $1 a year if the purchaser lives past 85—which implies that the reverse whole life policy (with limited premiums) costs $12.26. A typical whole life policy requires the purchaser to make annual payments, and upon the purchaser’s death, the insurance company pays a lump sum. The first part of an immediate annuity is structured in reverse—that is, the purchaser pays the lump sum up front and the insurance company makes annual payments but only until age 84. The first part of an immediate annuity and the first part of a traditional whole life insurance policy are actuarially equivalent when adjusted for the limited premiums. Abstractor’s Viewpoint The author makes a plea to financial advisers, who typically do not like annuities, “to recognize the huge risk-mitigating effect of longevity insurance.” I often say that annuities meet the needs of some investors but tend to be sold to those for whom there are better alternatives. I appreciate the author’s perspective of risk pooling—the way we buy fire insurance—for risk events that have a lower probability but a higher financial impact. I recognize the value of reasonably priced longevity insurance and hope that this article leads to insurance companies’ structuring contracts to meet this need. Editor’s note: This article was reviewed and accepted by Executive Editor Stephen J. Brown.
|
2022-09-14T10:09:34.120Z
|
99,076,630 |
{
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"ArXiv": null,
"DOI": "10.1039/C6RA28431K",
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"license": null,
"status": null,
"url": null
}
|
Non-contact optical thermometry using rare-earth materials has attracted a lot of attention due to its realization of non-invasive and real-time temperature determination. In the current work, a new mechanism, differing from the conventional approach utilizing the ratio of intensities emitted from two thermally coupled excited levels, was developed and demonstrated for temperature sensing using Eu3+-doped Ca3Sc2Si3O12 (CSSO). Under the excitation of 610.6 nm-wavelength light, Eu3+ ions at the 7F2 multiplet became excited to the 5D0 state, and then the luminescence intensity originating from the 5D0 state increased significantly as the temperature was increased from 123 K to 273 K. The thermoequilibrium of the 7F2 multiplet with the 7F0 ground state at a weak excitation ensured a steady increase of the luminescence intensity I with temperature T, which well fit the equation I = Aexp(−B/T) for the transitions to both 7F1 and 7F4 multiplets. A relative sensitivity SR of 1008/T2 was obtained for the 7F1 case, with a value of 1.35% at 273 K. This scheme, as a result of detecting the blue-shifted emission, has the advantages of being less disturbed by stray light from the host and the object of the thermometry. In addition, the high quantum efficiency of a one-photon excited photoluminescence scheme has the advantage of improving the resolution of the thermometry. Furthermore, a near-infrared broadband emission observed in the sample can be adopted as a reference, so as to transform the scheme into one using a luminescence intensity ratio. These results indicated that CSSO:Eu3+ may be used in practical temperature sensing applications.
|
2022-10-02T15:51:14.189Z
|
208,608,031 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1039/c9ob02509j",
"MAG": "2989779760",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this study, we report the reversible control of RNA interference using siRNAzos, a class of siRNAs that contain azobenzene. Herein, we demonstrate that it is possible to take an active siRNAzo, and inactivate it for up to 24 hours. We also demonstrate reversibility of these siRNAzos within cell culture. For example, active siRNAzos can be inactivated in cell culture with ultraviolet light, and then reactivated with visible light. In addition, we also show that siRNAzos can be activated and inactivated towards the endogenous target gene, BCL2.
|
2022-11-23T17:10:16.664Z
|
32,921,855 |
{
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"ArXiv": null,
"DOI": "10.1136/bcr-2014-206473",
"MAG": "1986423068",
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},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc4202059?pdf=render"
}
|
A 57-year-old man with symptoms of fatigue, joint pains and insomnia was found to have hypercalcaemia secondary to hyperparathyroidism with a corrected calcium of 2.61 mmol/L (2.2–2.6 mmol/L) and a serum parathyroid hormone (PTH) of 86 pg/mL (10–65 pg/mL). Preoperative workup demonstrated a parathyroid adenoma in the right upper position and he proceeded to surgery. Postoperatively, however, his symptoms remained unchanged and the corrected calcium remained elevated at 2.87 mmol/L with a PTH of 59 pg/mL. He had no family history of hypercalcaemia. Further investigations revealed low 24 h urinary calcium level and a low urine calcium to creatinine ratio. Genetic testing revealed a mutation in exon 4 of the calcium sensing receptor (CaSR) confirming a diagnosis of familial hypocalciuric hyercalcaemia (FHH). The case is an example of a rare phenomenon when a parathyroid adenoma develops in patients with FHH.
|
2022-12-18T11:00:24.662Z
|
1,736,660 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1128/IAI.70.3.1547-1557.2002",
"MAG": "2102621745",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
ABSTRACT Variations in the host response during pneumonia caused by Streptococcus pneumoniae in susceptible (CBA/Ca) and resistant (BALB/c) inbred mouse strains were investigated. Significant differences were detected in survival time, core body temperature, lung-associated and systemic bacterial loads, mast cell numbers, magnitude and location of cytokine production, lung disruption, and ability of isolated lung cells to release the cytokine tumor necrosis factor (TNF) alpha in vitro. Overall, the results indicate that the reduced capacity of CBA/Ca mice to induce rapid TNF activity within the airways following infection with S. pneumoniae may be a factor in their elevated susceptibility to pneumococcal pneumonia.
|
2022-12-21T10:22:48.783Z
|
146,495,897 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/0893318988001003005",
"MAG": "2163155759",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The ROCI-II, as one of the more recently developed instruments, is distinguished by its emphasis on individual predispositions, its belief in maintaining a balance in the amount of conflict in the organization, and its concern for effectiveness in managing conflicts. The scale treats communication implicitly as a set of strategies used to achieve interpersonal goals and as a way of equalizing the amount of conflict in the system. This article commends the internal reliabilities of the scale but questions the factor structure of the items. It calls for research on the predictive validity of the instrument and on the way to determine the appropriateness of a style in a particular situation.
|
2022-12-23T21:10:51.655Z
|
155,025,969 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/0958928711433655",
"MAG": "2075552389",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In what social contexts are rich people more likely to support government redistribution of income? Motivated by the literature on inequality aversion and the literature on the relationship between ethnic fractionalization and redistribution, the paper examines whether the relationship between own income and redistributive preferences depends on the regional level of poverty and the ethnic composition of the poor. Using data from the European Social Survey, the paper demonstrates that support for redistribution among the rich is lower when the proportion of ethnic minorities among the poor is high. Several possible mechanisms to account for this relationship are examined. The paper finds no support for explanations based on more animosity towards the poor or towards ethnic minorities and no support for explanations based on lower social trust or social capital: instead, rich people are less concerned with downward income mobility when the proportion of minorities among the poor is high.
|
2023-01-01T18:12:08.639Z
|
146,549,739 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2753/RSP1061-1967010458",
"MAG": "2248921179",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
During the period of extensive construction of communism in our country, when "the role of moral principles in the life of society is constantly increasing, and the sphere of action of the moral factor is expanding" (Programma Kommunisticheskoi partii Sovetskogo Soiuza [Program of the CPSU], Moscow, Gospolitizdat, 1961, p. 119), and when problems of moral education come to the fore, investigation of basic problems in the theory of morality becomes particularly pressing. One of these is the problem of a criterion for moral progress.
|
2022-02-09T05:52:23.394Z
|
127,535,801 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1306/703C9587-1707-11D7-8645000102C1865D",
"MAG": "2327261641",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A regional synthesis is presented of the stratigraphy of Jurassic strata in Egypt north of 30/degree/N, based on the study of about 80 wells and outcrops from northeastern Egypt. Almost all fossil groups have been investigated for biostratigraphic control. Published work on ammonite faunas from Gebel el Maghara (north Sinai) is integrated with extensive original work on palynofloras (and, to a lesser extent, ostracod/foraminiferal faunas) recovered from marine rocks in the subsurface. The recovery of rich dinocyst assemblages enables the recognition of a ten-fold zonation scheme, largely within the Middle-Late Jurassic sedimentary package. The upper limit of this package is marked by the Cimmerian erosional event; strata younger than Oxfordian are rarely preserved. Only east of 30/degree/E is significant sedimentation known to have occurred immediately prior to the major early Bajocian transgressive event. Thereafter mean sea level rose steadily. The Lower Triassic-Lower Jurassic sedimentary package is poorly understood, largely the result of scanty and ambiguous stratigraphic evidence. However, regional correlations suggest that only very thin earliest Jurassic (Hettangian ) clastic deposition succeeded a sequence of Upper Triassic carbonates and evaporites (Wadi en Natrun Formation) in the north. Arising from these studies is a standard lithostratigraphical scheme. The upper sedimentary package,more » the Gebel el Maghara Group, comprises three formations (Masajid, Khatatba, and Inmar) and seven members; new units are defined and old units redefined.« less
|
2022-06-18T19:01:30.228Z
|
154,700,008 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S0305741000025224",
"MAG": "2147018311",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The cultural level of North Vietnam is undoubtedly one of the lowest imaginable. Eighty per cent, of the population is illiterate, ignorant to an incredible degree and subject to the most extraordinary superstitions. Apart from the masses there remains the élite—and the hopes that one should be able to place in the youth. But here, also, we find the same deep division that was created in the population as a whole by the war—on the one hand the members of the Resistance and on the other those who remained outside it.
|
2022-06-23T10:23:45.123Z
|
238,235,896 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1371/journal.pone.0266922",
"MAG": null,
"PubMedCentral": "9015134"
},
"license": "CC0",
"status": "GOLD",
"url": "https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0266922&type=printable"
}
|
Background Maintenance drugs are used to treat chronic conditions. Several classes of maintenance drugs have attracted attention because of their potential to affect susceptibility to and severity of COVID-19. Methods Using claims data on 20% random sample of Part D Medicare enrollees from April to December 2020, we identified patients diagnosed with COVID-19. Using a nested case-control design, non-COVID-19 controls were identified by 1:5 matching on age, race, sex, dual-eligibility status and geographical region. We identified usage of angiotensin-converting enzyme inhibitors (ACEI), angiotensin-receptor blockers (ARB), warfarin, direct factor Xa inhibitors, clopidogrel, famotidine and hydroxychloroquine based on Medicare prescription claims data. Using extended Cox regression models with time-varying propensity score adjustment we examined the independent effect of each study drug on contracting COVID-19. For severity of COVID-19, we performed extended Cox regressions on all COVID-19 patients, using COVID-19-related hospitalization and all-cause mortality as outcomes. Covariates included gender, age, race, geographic region, low-income indicator and co-morbidities. To compensate for indication bias related to the use of hydroxychloroquine for the prophylaxis or treatment of COVID-19, we censored patients who only started on hydroxychloroquine in 2020. Results Up to December 2020, our sample contained 374,229 Medicare patients over 65 who were diagnosed with COVID-19. Among the COVID-19 patients, 209,208 (55.9%) were on at least one study drug. The three most common study drugs were ACEI 97,872 (26.1%), ARB 83,329 (22.3%) and clopidogrel 38,203 (10.2%). Current users of ACEI, ARB, warfarin, direct factor Xa inhibitor and clopidogrel were associated with reduced risk of getting COVID-19 (3-13%), and reduced risk of dying after a COVID-19 diagnosis (8-19%). Famotidine did not show consistent significant effects. Hydroxychloroquine did not show significant effects after censoring of recent starters. Conclusions Maintenance use of ACEI, ARB, warfarin, direct factor Xa inhibitor and clopidogrel was associated with reduction in risk of acquiring COVID-19 and dying from it.
|
2022-09-25T06:43:26.090Z
|
37,025,233 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/LEOSWT.2008.4444444",
"MAG": "1992018654",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Microstructuring techniques, initially developed for photonic band gap fibers are being increasingly adapted for active fiber systems due to superior design space in effective area, polarization maintenance and dispersion control.
|
2022-02-12T07:13:51.200Z
|
3,605,040 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/GCCE.2017.8229222",
"MAG": "2780839360",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this paper, a method of recording food intake using intra-body communication technology and estimating food sizes by measuring its electrical properties is described. The method uses high-frequency signals to detect contact and estimate food sizes when the food makes contact with the cutlery before consumption. Previous studies have addressed detection of food contact and identification of food. The present study estimates food size by using the signal power-frequency pattern obtained from the receiver.
|
2022-02-13T12:31:06.348Z
|
208,236,304 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/028418515304000405",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
For more than ten years rotatory therapy used at the Radium Centre, Aarhus, has been based on HOWARD NIELSEN'S study on this method of irradiation at 155 kV. A large number of dose measurements in phantoms made it possible to formulate irradiation programmes for malignant diseases in various organs. However, after the installation of a new roentgen therapy unit (G. E. Maximar "400") it is now possible for us to use a voltage of 400 kV. and a harder quality of radiation. The purpose of this paper is to present the isodoses found in new dose measurements in phantoms. RAMA RAU, who collected information on 400 kV. therapy, treated 1,210 patients with irradiation through several portals, using HVL of from I to 5 mm Cu. He found that no serious complications developed during treatment. Nausea and vomiting were exceptional, and diarrhea occurred in less than 3 per cent of the patients who received radiation to the abdomen. Moreover, as has also been pointed out by CARTER WOOD, the skin reactions were milder than with identical doses at 180 kV. or 200 kV. (HVL I or 2 mm Cu). In rotatory irradiation, as in cross-fire treatment, it is of importance to realize to what extent it is possible to increase the depth effect of radiation. In rotatory therapy the problem as to the proper placement of the dosage maximum is superadded. As shown by HOWARD NIELSEN, the conditions for an advantageous distribution of the radiation are extremely difficult in the pelvic region at HVL of 0.7-1.0 mm Cu. The massive pelvic bones influence to a great extent on the shape of the isodoses, and two dose maxima occur. As the absorption coefficient of osseous tissue is about 3.5 times as high as that of soft tissues at a
|
2022-09-03T08:00:44.790Z
|
23,865,845 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1442-200X.2008.02563.x",
"MAG": "1991638694",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Background: The aim of the present study was to gain a better understanding of the motor performance in Williams syndrome for early intervention of rehabilitation programs.
|
2022-12-11T07:34:15.355Z
|
12,528,539 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1001/ARCHSURG.1955.01270160012002",
"MAG": "2022526986",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The search for a simple and ever-ready material for bridging defects in large arteries, to reestablish the flow of arterial blood to the distal parts of an extremity or to vital structures of the body, has been pursued by investigators for many decades. In 1900 Payr 1 published the results of experimental studies with absorbable and non-absorbable materials and he concluded that collars and tubes of absorbable magnesium, lined by autogenous venous grafts, functioned satisfactorily when used to bridge defects in large arteries. In 1906 Carrel 2 studied the problem of suturing blood vessels and later used autogenous venous grafts, homologous arterial grafts, and heterologous arterial grafts to bridge defects in arteries in animals. The first World War gave Tuffier 3 an opportunity to use tubes of various metals to bridge defects of large arteries produced by wounds of war. In the decade 1930-1939, our 4 attention was centered around
|
2022-09-15T09:28:23.932Z
|
30,073,190 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/1087057108317060",
"MAG": "2159026701",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "HYBRID",
"url": "https://journals.sagepub.com/doi/pdf/10.1177/1087057108317060"
}
|
Small-molecule inhibitors of HIV integrase (HIV IN) have emerged as a promising new class of antivirals for the treatment of HIV/AIDS. The compounds currently approved or in clinical development specifically target HIV DNA integration and were identified using strand-transfer assays targeting the HIV IN/viral DNA complex. The authors have developed a second biochemical assay for identification of HIV integrase inhibitors, targeting the interaction between HIV IN and the cellular cofactor LEDGF/p75. They developed a luminescent proximity assay (AlphaScreen™) designed to measure the association of the 80-amino-acid integrase binding domain of LEDGF/p75 with the 163-amino-acid catalytic core domain of HIV IN. This assay proved to be quite robust (with a Z′ factor of 0.84 in screening libraries arrayed as orthogonal mixtures) and successfully identified several compounds specific for this protein-protein interaction. (Journal of Biomolecular Screening 2008:406-414)
|
2022-12-17T07:40:30.150Z
|
13,751,339 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1142/S0218126618501372",
"MAG": "2771355696",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper presents a supper class-AB adaptive biasing bulk-driven amplifier for ultra-low-power applications. In the proposed structure, two bulk-driven flipped voltage follower (FVF) cells are reconfigured as nonlinear tail currents using quasi-floating gate method to enhance transconductance and slew rate. In addition, two idle current controllers are employed as common source amplifiers to provide a supper class-AB structure without increasing total current consumption. The proposed structure is simulated in 0.18-μm CMOS technology at 0.5V supply with 35nW power budget. The results show a 57.9dB DC gain, 8.8kHz gain bandwidth and 38.2V/ms slew rate for the proposed amplifier.
|
2022-12-25T20:31:06.668Z
|
197,732,961 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.29252/AUMS.8.2.150",
"MAG": "2953159686",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Background and Aim: multiple sclerosis is a degenerative disease of central nervous system that causes a lot of psychological problems. the aim of this study was to investigate the cognitive, emotional and social factors in the psychological problems of patients with multiple sclerosis and healthy people . Material and Methods: the method of this study was descriptive from its comparative casual types. Statistical population of this study was all of patients with multiple sclerosis were referred to M.S association in the urmia. Sample of this study was 40 patients with multiple sclerosis were referred to M.S association in the urmia and selected by available sampling method. Data were analyzed by Multivariate Analysis of Variance and one-way analysis of variance. Results: The results of this study showed that there is significant deference between two groups in the variables of looming maladaptive style (F=6/526, sig:0/002), negative problem-orientation (F=4/26, sig:0/04), interpersonal emotion regulation (F=3/195, sig:0/02), emotional processing styles (F=2/503, sig:0/04), social desirability (F=18/29, sig:0/000) and rejection sensitivity (F=4/00, sig:0/049) and patients with multiple sclerosis get the higher scores in these variables but there is no differences between two groups in meta-worry. Conclusion: Many psychological problems that these patients experience are in part as a result of cognitive, emotional and social factors that have been studied in current study. Then, paying attention to these factors in the etiology and treatment of psychological problems of these patients can be a useful step in the reducing of these problems and improving of mental health in the patients. Multiple sclerosis, Emotional Social factors Abstract
|
2022-07-15T16:13:35.753Z
|
52,187,433 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/9781316676202.012",
"MAG": "2736017469",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
The human body plays an important role in face-to-face interactions (Knapp & Hall, 2010; McNeill, 1992).We use our bodies to regulate turns, to display attitudes and to signal attention (Scheflen, 1964). Unconsciously, the body also reflects our affective and mental states (Ekman & Friesen, 1969). There is a long history of research into the bodily behaviors that correlate with the social and affective state of a person, in particular in interaction with others (Argyle, 2010; Dittmann, 1987; Mehrabian, 1968). We will refer to these behaviors as bodily social signals. These social and affective cues can be detected and interpreted by observing the human body’s posture and movement (Harrigan, 2008; Kleinsmith & Bianchi-Berthouze, 2013). Automatic observation and analysis has applications such as the detection of driver fatigue and deception, the analysis of interest and mood in interactions with robot companions, and in the interpretation of higher-level phenomena such as mimicry and turn-taking. In this chapter, we will discuss various bodily social signals, and how to analyze and recognize them automatically. Human motion can be studied on many levels, from the physical level involving muscles and joints, to the level of interpreting a person’s full-body actions and intentions (Poppe, 2007, 2010; Jiang et al., 2013). We will focus on automatically analyzing movements with a relatively short time scale, such as a gesture or posture shift. In the first section, we will discuss the different ways of measurement and coding, both from motion capture data and images and video. The recorded data can subsequently be interpreted in terms of social signals. In the second section, we address the automatic recognition of several bodily social signals. We will conclude the chapter with a discussion of challenges and directions of future work.
|
2022-10-03T16:47:38.318Z
|
72,160,358 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2337/DIACLIN.31.1.1",
"MAG": "2042149236",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
W ith all the challenges of modern health care practices, the proliferation of certification for medical necessity (CMN) forms and other documentation requirements has become an increasing distraction from conversing with, examining, and critically thinking about patients. In particular, CMNs for self-monitoring of blood glucose (SMBG) have become a major impediment.
In 2011, diabetes care providers were notified by the Center for Medicare and Medicaid Services (CMS) about new regulations to obtain coverage for blood glucose monitoring strips for individuals with diabetes. Those using only oral agents are allowed 100 strips for 90 days; those using insulin are allowed up to 100 strips per month.
This will suffice for many Medicare-covered patients. However, those of us who scrupulously review glucose diaries and meter downloads and use this information to adjust intensive regimens or to help complicated patients achieve their glucose goals know there are many patients for whom these restrictions will not work. Many seniors or disabled individuals are prone to hypoglycemia because of extreme insulin deficiency or erratic dietary intake. Many require multiple injections of adjustable-dose insulin or use insulin pumps. Performing SMBG three times per day will not suffice …
|
2022-06-11T13:56:13.940Z
|
177,593,930 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.22278/2318-2660.2009.V33.N4.A278",
"MAG": "1566718947",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
O objetivo te trabalho foi pesquisar o risco da violencia na relacao mae-bebe em sua interface com o humor materno no puerperio apos parto prematuro. A metodologia utilizada foi a pesquisa qualitativa em saude, mediante a utilizacao da tecnica de construcao de historias de vida, com base na unidade temporal do periodo relativo ao projeto de maternidade apos o parto prematuro. Os resultados encontrados apontaram para a necessidade de realizacao de uma intervencao que focalizasse o risco de violencia oferecendo, ao mesmo tempo, um suporte as experiencias emocionais maternas caracteristicas do puerperio. Concluiu-se que existe uma distância compreensiva entre as prescricoes oferecidas no momento da alta hospitalar e a realidade experienciada pela dupla mae-bebe no ingresso em ambiente domestico. Existe, portanto, uma demanda por intervencoes relacionadas com o humor materno apos a alta hospitalar, sendo evidenciado que a psicoterapia mae-bebe e uma ferramenta a ser utilizada na prevencao de riscos de violencia.
|
2022-01-24T19:36:23.234Z
|
83,503,008 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1590/S0102-09352003000200021",
"MAG": "1983012798",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
To study the passive immunity transference to the new born foal via colostrum, the total serum protein of 27 foals, being 13 females and 14 males, born from multiparae and primiparae mares was estimated. The blood samples were colected at 6, 12, 18, 24 and 30 hours after the first suckling. The total protein values increase significantly between 6 and 12 hours after the first suckling, being not influenced by the sex of the foal. The total protein values of new borns from multiparae mares were significantly higher than primiparae mares at 12 hours after the first suckling and was mantained in the same levels for 30 hours. It was concluded that the newborn Arabian foals had the highest immunoglobulin absortion between 6 and 12 hours after the first suckling and it is higher in foals born from multiparae than from primiparae mares.
|
2022-02-11T01:18:54.059Z
|
25,571,551 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S0952523806231018",
"MAG": "2137065941",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Gap junctions provide a pathway for the direct intercellular exchange of ions and small signaling molecules. Gap junctional coupling between retinal astrocytes and between astrocytes and Müller cells, the principal glia of vertebrate retinas, has been previously demonstrated by the intercellular transfer of gap-junction permeant tracers. However, functional gap junctions have yet to be demonstrated between mammalian Müller cells. In the present study, when the gap-junction permeant tracers Neurobiotin and Lucifer yellow were injected into a Müller cell via a patch pipette, the tracers transferred to at least one additional cell in more than half of the cases examined. Simultaneous whole-cell recordings from pairs of Müller cells in the isolated rabbit retina revealed electrical coupling between closely neighboring cells, confirming the presence of functional gap junctions between rabbit Müller cells. The limited degree of this coupling suggests that Müller cell–Müller cell gap junctions may coordinate the functions of small ensembles of these glial cells. Immunohistochemistry and immunoblotting were used to identify the connexins in rabbit retinal glia. Connexin30 (Cx30) and connexin43 (Cx43) immunoreactivities were associated with astrocytes in the medullary ray region of the retinas of both pigmented and albino rabbits. Connexin43 was also found in Müller cells, but antibody recognition differed between astrocytic and Müller cell connexin43.
|
2022-12-20T16:27:33.188Z
|
28,469,023 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICETC.2010.5529523",
"MAG": "2107955759",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Increasing advances in learning technologies has leaded to many areas of research, such as e-learning, managing e-learning contents and yielded many standards and platforms. Researchers and developers are enhancing e-learning but passed over developing or enhancing classical learning technologies (i.e. developing solutions for regular learning activities not involving e-learning). In this paper we introduce visualization of professor efficacy parameters in pursuit of better quality learning and lecturing in universities.
|
2022-02-12T14:16:06.037Z
|
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