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255M
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252,307,030 |
{
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"DOI": "10.1145/3543829.3543833",
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"url": "https://dl.acm.org/doi/pdf/10.1145/3543829.3543833"
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|
Interacting with long lists of instructions or ingredients continues to be a challenge for conversational interaction. In this paper, we conducted a user study to experiment with the use of ‘cued-gaze’ – waiting for the user’s visual attention – to manage the delivery of instructions with a voice agent. In a Wizard-of-Oz setting, 12 participants were instructed to build a simple Lego tower by a conversational agent and were able to advance in the list using either speech interaction, or gaze interaction. The increasing use of speech agents in real-world cause users to encounter failures in interactions, so in this task the agent was designed to fail when providing the list of instruction to explore how the participants proceeded to recover from common failures. This showed that, for this use case, cross-modality repair was more effective than reformulation of speech.
|
2022-12-17T10:27:22.081Z
|
118,047,437 |
{
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"DOI": "10.1515/crll.1987.375-376.157",
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|
We consider the problem of determining, for a given family of Galois extensions N l K with Galois group A9 their relative Galois module structure, that is, the ring of integers ON s module over the group ring OKA. In order to get a grip on this problem we ask and answer here in a number of cases first the possibly more restricted question: what, if anything, obstructs the Galois modules from being free? The answer is: complex conjugation.
|
2022-12-18T10:44:21.683Z
|
247,027,335 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3389/fsurg.2022.836335",
"MAG": null,
"PubMedCentral": "8906498"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.frontiersin.org/articles/10.3389/fsurg.2022.836335/pdf"
}
|
Objectives Numbers of PIV are rising. The aim of this study is to analyze the surgical learning-curve (LC) on the grounds of perioperative complications. Patients and Methods 108 PIVs, performed by a single surgeon between 2015 and 2018 have been analyzed. Learning-curve analysis was based on three factors: operating time, vaginal depth and complications. Results The median FU was 6.3 months. Median age at surgery was 36 years, median time of hormone treatment was 36 months. The median CI was 0.3 and the median BMI was 25 kg/cm3. Median CCI® was 8.08. 40.7% of the patients developed short-term complications, more than half of which were Clavien I. Overall only 1.9% had Clavien IIIb complications. There were no Clavien IV or V complications. 17.6% of patients had wound infections, 13% wound dehiscence, 9.3% introitus strictures, 13.9% suffered from atrophy of the neovagina, i.e. loss of depth or width, and 8.3% from meatus urethrae strictures. Duration of hormonal therapy, BMI and CI had no impact on surgical outcome. Age had a significant impact on CCI®, as younger patients had a higher risk for complications. Use of scrotal skin and surgeries performed had a significant influence. LC analysis via CUSUM analysis showed that after 32 surgeries, the PIV is performed safely. Conclusion The PIV is a safe GAS-technique, associated with minor complications leading to low rates of revision surgery. Younger age, the use of scrotal skin and surgeon's experience has significant impact on complications. Duration of hormonal therapy, circumcision and BMI has no impact on complications.
|
2022-12-24T18:14:09.898Z
|
62,348,692 |
{
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"ArXiv": null,
"DOI": "10.1527/TJSAI.30.491",
"MAG": "2317087491",
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"status": null,
"url": null
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|
In order to investigate the formation mechanism of community activity, we constructed an agent-based model based on a scenario driven by subjective norm and self-efficacy utilizing a community task game. The model demonstrated the spontaneous formation of community activity. The formation and expansion were driven by two mechanisms: (1) self-efficacy maintained participation of agents having a neutral attitude towards community activity, (2) subjective norm caused an increase in participation by involving other adjacent neutral attitude agents. We suggest a reasonable strategy promoting the spontaneous formation of community activity on the basis of this mechanism.
|
2022-02-11T14:45:07.405Z
|
27,389,950 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CEEM.2009.5303481",
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|
A novel multiband FSS based on Y-loop element has been analyzed using FDTD method. The simulated results show that the proposed FSS has the advantages of low insertion loss in pass-band, good frequency selectivity and stability of bandwidth. Its performance is very stable at various incident angles but sensitive for different polarization state at Ku-band for the lack of symmetry. Besides, there is no other resonance frequency from 10GHz to 40GHz expect the desired frequency (12.5GHz and 35GHz). It indicates that the novel multiband FSS has eliminated the parasitic resonance compared with the Y-loop fractal element.
|
2022-02-12T15:31:42.699Z
|
37,743,358 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/93.998042",
"MAG": "2013486023",
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"license": null,
"status": null,
"url": null
}
|
Airlines and governments are using various multimedia technologies to persuade the public that it's okay to fly again. What's being tested and how will it affect your flying experience? Airports around the world are taking drastically different approaches and employing diverse technologies. For now, most multimedia technologies being tested at airports involve biometrics. The article looks at biometric developments.
|
2022-09-07T21:33:20.552Z
|
244,938 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/TIT.1969.1054258",
"MAG": "2143473381",
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"license": null,
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"url": null
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|
This paper describes a technique for high-speed decoding of burst-error-correcting codes and a class of codes most suitable for this purpose. With a small amount of additional circuitry the decoders proposed in this paper are capable of decoding speeds several orders of magnitude higher than those of conventional decoders.
|
2022-09-14T08:56:14.858Z
|
154,144,380 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2307/2534267",
"MAG": "1976716529",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://www.brookings.edu/wp-content/uploads/1978/06/1978b_bpea_seidman_gordon_okun.pdf"
}
|
GIVEN the institutional features and ethical norms of modem labor markets and the income-maintenance programs of the welfare state, it appears that substantial macroeconomic slack is required to keep the rate of wage inflation and therefore the rate of price inflation from accelerating. Because of these deviations from a purely atomistic, competitive labor market, the unemployment rate required to prevent a rise in wage inflation is economically inefficient. The central policy problem, therefore, is to reduce this nonaccelerating-inflation rate of unemployment (NAIRU) of the economy. The aim of an incomes policy is to introduce a direct restraint on the growth rate of money wages and salaries, so that less macroeconomic slack is required to keep the inflation rate from accelerating. Traditionally there have been two methods of implementing an incomes policy: persuasion and controls. Each has serious shortcomings as a permanent policy. A microeconomic perspective, however, leads naturally to tax incentives, a new method of implementing an incomes policy. A comparison with the environmental pollution problem is instructive.' Few economists seriously advocate persuasion because in the microeconomic sphere it is taken as an axiom that each economic agent will pursue his own self-
|
2022-09-15T02:03:46.363Z
|
245,455,427 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3126/pjri.v3i1.41636",
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},
"license": "CCBYNC",
"status": "HYBRID",
"url": "https://www.nepjol.info/index.php/pjri/article/download/41636/31648"
}
|
Financial sources and corporate investment are the key components for business operation and corporate activities focus on to increase efficiency. The study has attempted to analyze the impact of leverage and firm-specific variables on efficiency of Nepali hotel industry. In this study, efficiency is the dependent variables whereas the independent variables are leverage, size, tangibility and growth. The descriptive and causal comparative research design has been used to examine and analyze the impact on efficiency. The data were collected from annual reports of respective hotels. The study was based on 18 observations and the sample comprises of three hotels, which were purposively selected. Descriptive statistics, correlation and regression analysis have been employed to assess the relationship among the variables. The result showed that the hotels having high leverage have higher efficiency. This study concluded that size, leverage, growth and tangibility are the major factors to determine and increase the corporate efficiency. The findings of the study suggested that there are practical implications to take financing, investment and operating decisions of service sectors like hotels of Nepal. The study has also aimed to support the increase in corporate efficiency.
|
2022-09-30T01:47:42.411Z
|
201,989,429 |
{
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"ArXiv": null,
"DOI": "10.1055/S-0039-1694019",
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|
Objetivo O objetivo deste estudo foi avaliar a associação da anteversão femoral e da força dos músculos do quadril em indivíduos com síndrome do impacto femoroacetabular.
Método Os ângulos de versão femoral descritos nas imagens de ressonância magnética articular e os testes isocinéticos foram avaliados retrospectivamente entre julho de 2016 e dezembro de 2017. Os critérios de inclusão foram: a) versão femoral avaliada pelo mesmo radiologista; b) ângulo α ≥ 55°; e c) ausência de dor limitante durante o teste isocinético. Os picos de torque em flexão/extensão, abdução/adução e rotação interna/externa foram avaliados a 30°/s em 5 repetições. A correlação entre a versão femoral e a força muscular foi avaliada por meio de regressão linear simples, com nível de significância estatística de 5%.
Resultados Um total de 37 mulheres atenderam aos critérios de inclusão. Foram avaliados 51 quadris sintomáticos. Não houve correlação da anteversão femoral nos picos de torque em flexão, extensão, abdução, adução, rotação externa e rotação interna.
Conclusão A anteversão femoral não foi correlacionada à força dos músculos do quadril em mulheres com impacto femoroacetabular sintomático.
|
2022-12-10T09:14:37.166Z
|
221,036,313 |
{
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"ArXiv": null,
"DOI": "10.1109/ITEC48692.2020.9161454",
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"status": null,
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|
Due to the inherent misalignment variations in wireless electric vehicle (EV) charging systems, particularly in dynamic charging modes, it is essential to acknowledge the misalignment performance in the design and optimization of the coupling coils and the shielding layers. In this work, a heuristic inductive link design approach is presented, in which the coupling performance of rectangular RIPT coils is evaluated over a range of lateral misalignments for different coil parameters and shielding layer thickness. Accordingly, recommendations are made on the inductive link design that provides good coupling behavior, sufficiently high power transfer efficiency and effective shielding performance over a wide range of lateral misalignments.
|
2022-12-10T00:26:48.586Z
|
97,009,266 |
{
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"ArXiv": null,
"DOI": "10.1115/PVP2015-45286",
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|
As continuation of recently published experimental work [1,2], the static equivalent pressures (“pstat“) of the different detonative pressure scenarios occurring in stoichiometric H2/O2/N2 mixtures were determined in long and short pipes at ambient initial temperatures (20 °C) and initial pressures ranging from 4 bar abs to 35 bar abs. The pipes used for the tests were about 10 m long and had radial dimensions of 48.3×2.6 and 114.3×3.6 (outer diameter [mm] × wall thickness [mm]). The O2 content was varied from about 10 vol.-% to the highest value possible in stoichiometric mixtures (33.3 vol.-%).For the tests in the long pipes the focus was on the variation of the ratio between the static equivalent pressure at the point where transition from deflagration to detonation occurred and the static equivalent pressure in the region of the stable detonation (pstat_DDT_long / pstat_stable). The ratio attained a maximum of about 5 at 14.78 vol.-% O2 (stoichiometric H2/air) and decays to 1 when increasing the O2 content to 24 vol.-%. This drop indicates that with increasing O2 content ever less precompression is required to cause auto ignition in the precompressed gas directly ahead of the deflagrative flame front. For mixtures of H2 with N2-diluted air the ratio exhibits a slight decrease which is in contrast to what would be expected and is not yet understood. The results obtained for the ratio between pstat of scenarios 3 and 4 (stable detonation and reflected stable detonation) and the Chapman-Jouguet pressure of the investigated gas mixtures confirmed the findings presented in PVP2013-97677 for ethylene/air-mixtures.For mixtures of H2 and slightly diluted air the load for the reflected instable detonation was found to be about 7 · pstat_stable, the load at the DDT in the short pipe is 6.6 · pstat_stable and the load for coalescence of DDT and reflection is about 14 · pstat_stable.Copyright © 2015 by ASME
|
2022-12-19T21:44:28.024Z
|
148,667,498 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1080/14660970.2017.1323738",
"MAG": "2611663872",
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"status": null,
"url": null
}
|
What are the myths and realities of the Scandinavian sport model? The author analyses four constituents of the Scandinavian sport model, using Norwegian football as an example. For adult football, there is clear discrepancy between conceptions and realities, while the current model describes the realities of children’s and youth football fairly accurately. The author reports and analyses interviews with leaders of an elite sports club and a sport-for-all club, as well as the results of a survey of 155 coaches of children’s and youth football. The survey and interviews reveal that Norwegian football is a divided house, possibly signalling future trends in Scandinavian sport as a whole. Whether the distinguishing features of Scandinavian sport will continue is an open question.
|
2022-12-30T15:49:25.101Z
|
201,448,316 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.17748/2075-9908-2011-0-5-59-64",
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"license": null,
"status": "CLOSED",
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|
Ключевые слова: народное образование, казачья культура, педагогическое образование, учительская семинария. The article considers activit y of official bodies of Co ssack power of Kuban region in relation to changing the system of popular education for Cossack class in th e light of the changes taken place in the middle of t he 19th century in all the life spheres of the Russian Empi re. The main attention has been paid to the problem of teacher s’ training i.e. the main problem in the sphere of edu cation of that time in Kuban.
|
2022-02-08T05:08:25.912Z
|
42,223,329 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ROBOT.1998.680702",
"MAG": "2161635220",
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|
This paper presents an autonomous mobile system in an outdoor environment especially applied to a construction site. The system consists of an autonomous vehicle and signs. The autonomous vehicle recognizes instructions given in the signs using a vision system, then it moves or handles materials according to the instruction. The system is adaptable to the changeable environment of the construction site because transportation paths can be easily changed by altering the contents or placement of the signs. Experimental results obtained in the outdoor environment show feasibility of the system.
|
2022-02-12T03:05:56.665Z
|
97,121,049 |
{
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"ArXiv": null,
"DOI": "10.1002/JLAC.1990199001163",
"MAG": "2079172488",
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"license": null,
"status": null,
"url": null
}
|
The cyclic peptide cyclo[-L-Pro-L-Leu-D-(Gln)Thz-(Gly)Thz-L-Val-] (1a), which is a diastereomer of the antineoplastic agent dolastatin 3 (1b), and contains the unusual thiazole amino acids, was synthesized. All the peptide bonds of the cyclic peptide 1a are trans in solution, and the compound is conformationally homogeneous, as deduced by CD spectroscopy and comprehensive NMR spectroscopy. The conformation was refined by SYBYL molecular force-field calculations. The saddle-like conformation contains three intramolecular, but no transannular hydrogen bonds.
|
2022-08-27T06:03:56.405Z
|
97,662,164 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1002/CBER.19891220315",
"MAG": "2124419843",
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"license": null,
"status": null,
"url": null
}
|
Diphenylacetylene Complexes of Molybdenum: [MoCl4(PhCCPh)(POCl3)] and the Crystal Structure of [MoCl4(PhCCPh)]2
The monomeric alkyne molybdenum(IV) complex [MoCl4-(PhCCPh)(POCl3)] (1) is prepared by the reaction of MoCl5 with diphenylacetylene in CH2Cl2 solution in the presence of POCl3. According to spectroscopic results, the alkyne ligand in 1 forms a metallacyclopropene structure. In diluted CH2Cl2 solutions, 1 dissociates forming [MoCl4(PhCCPh)]2 (2) and POCl3. The crystal structure determination of 2 leads to the space group p21/n. 2 forms centrosymmetric dimeric molecules with MoCl2Mo bridges.
|
2022-09-13T12:25:46.811Z
|
237,801,422 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1175/JHM-D-20-0314.1",
"MAG": "3183033689",
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"license": null,
"status": null,
"url": null
}
|
Climate models are frequently-used tools for adaptation planning in light of future uncertainty. However, not all climate models are equally trustworthy, and so model biases must be assessed to select models suitable for producing credible projections. Drought is a well-known and high-impact form of extreme weather, and knowledge of its frequency, intensity, and duration key for regional water management plans. Droughts are also difficult to assess in climate datasets, due to the long duration per event, relative to the length of a typical simulation. Therefore, there is a growing need for a standardized suite of metrics addressing how well models capture this phenomenon. In this study, we present a widely applicable set of metrics for evaluating agreement between climate datasets and observations in the context of drought. Two notable advances are made in our evaluation system: First, statistical hypothesis testing is employed for normalization of individual scores against the threshold for statistical significance. And second, within each evaluation region and dataset, principal feature analysis is used to select the most descriptive metrics among 11 metrics that capture essential features of drought. Our metrics package is applied to three characteristically distinct regions in the conterminous US and across several commonly employed climate datasets (CMIP5/6, LOCA and CORDEX). As a result, insights emerge into the underlying drivers of model bias in global climate models, regional climate models, and statistically downscaled models.
|
2022-11-10T16:23:30.565Z
|
136,663,408 |
{
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"DOI": "10.4028/www.scientific.net/AMR.194-196.326",
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|
The dynamic coefficient of thermal expansion for steel Q235 during cooling was investigated using experimental measurements and model calculations. The coefficient of thermal expansion under 1400°С was measured with a thermal dilatometer. The coefficient was derived from a segregation model of two-phase zone for of temperature range of 1400°С to zero-strength temperature (ZST). The obtained results reveal that the coefficient of thermal expansion shows two jumps in the temperature zone of the peritectic reaction and the eutectoid reaction. The anti-expansion phenomenon caused by the eutectoid reaction in the cooling process corresponds to the low-temperature crack-sensitive area. Therefore, the slab straightening process should be avoided in this temperature range during continuous casting.
|
2022-07-23T11:54:01.225Z
|
3,050,553 |
{
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"DOI": "10.4269/ajtmh.13-0121",
"MAG": "2158244271",
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},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc3820314?pdf=render"
}
|
The distribution of norovirus (NoV) genogroup II in children < 5 years of age admitted to a south Indian hospital with diarrhea was investigated. Viral RNA extracted from 282 stool samples were screened for NoV GII and positive amplicons sequenced. Twenty-eight (9.9%) had NoV GII infection with a median age of 6 months, with more severe episodes of diarrhea among infected (median Vesikari score 13, interquartile range [IQR] 10-15) than children without infection (median score 10, IQR 8-13, P = 0.002). The study documents NoV GII infections as an important cause of gastroenteritis and the genetic diversity of circulating strains.
|
2022-11-29T15:56:29.502Z
|
149,213,727 |
{
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"DOI": "10.1080/13676261.2017.1366015",
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"url": null
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|
ABSTRACT Post-Fordist employment is characterised by the demand for new forms of labour in which workers are expected to make personal investments in their work and to mobilise their embodied subjectivities in the practice of labour. Whilst employment insecurity is well documented in the sociology of youth, theoretical development in this area has yet to contend with the role of changes in the nature of labour itself in the production of youth. This paper draws on theories of labour under post-Fordism to explore the practice of ‘affective labour’ amongst young people performing ‘front of house’ bar work in a large metropolitan service economy. The paper theorises the role of youth subjectivities – including capacities for relationality and leisure, gendered embodiment, and tastes – in the practice of contemporary labour. The paper describes how young people doing bar work contribute to the production of affective atmospheres, or sensations of ease, pleasure and enjoyment that are offered to clientele of boutique bars. In this, we suggest that affective labour mobilises young subjectivities at work in ways that are currently unrecognised within youth studies. The paper concludes by suggesting a new research agenda that goes beyond the existing focus on youth transitions through employment to explore how youth is produced as part of the social dynamics of post-Fordist labour.
|
2022-12-02T15:59:41.347Z
|
15,894,609 |
{
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"DOI": "10.1109/RNDM.2016.7608284",
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"url": null
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|
Growing popularity of content-oriented services is a significant trend observed recently in communication networks. Due to large volumes of traffic related to these services, the network operators search for new solutions that allow to deliver content to end users in a cost-effective manner. Elastic optical network (EON) is a relatively novel solution for optical networks. The main advantages of EONs compared to traditional wavelength division multiplexing (WDM) optical networks are more efficient use of spectrum resources and support of flexible modulation format conversion. Moreover, there is a strong focus on multicasting, which is perceived as a much better approach for content delivery compared to unicast transmissions. In this paper we concentrate on dynamic multicast routing in survivable EONs. We compare various protection methods that may be applied to protect multicast sessions in EONs. For this purpose, we adapt two dynamic routing algorithms with additional survivability constraints and the possibility to change the modulation format at the regeneration nodes. Using realistic assumptions on EONs and representative network topologies, a wide range of simulations is run. First, we show the results to indicate advantages and disadvantages of various protection methods. In addition, we show gain of enabling partial protection of receivers in multicast trees. The results clearly show that various QoS levels for multicast protection allow to save optical network resources, thus, accept more incoming traffic in the network.
|
2022-12-14T00:13:10.269Z
|
143,831,676 |
{
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"DOI": "10.1111/J.1745-9125.1986.TB00382.X",
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|
When modern policing in cities developed in the United States, detection was more a private than a public matter. Once public detectives became an integral part of police departments, their role and activities gradually changed. Between the middle of the 19th and 20th centuries, detectives evolved through three phases: secretive rogue, inquisitor, and bureaucrat.
|
2022-12-15T00:36:35.043Z
|
23,478,854 |
{
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"DOI": "10.1002/hep.21826",
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"license": null,
"status": "BRONZE",
"url": "https://aasldpubs.onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hep.21826"
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|
Hepatocellular carcinoma (HCC) is the most frequent cause of death in patients with hepatitis C virus (HCV)–induced cirrhosis. Despite a number of studies in different populations worldwide suggesting an association between HCV genotype 1 and the risk of HCC, no consensus has emerged yet on this matter, which is still controversial. In an attempt to clarify this issue, a prospective study of 163 consecutive HCV‐positive patients with cirrhosis, who were enrolled between January 1989 and December 1990, was carried out. HCC occurrence was detected by ultrasound surveillance every 6 months. Independent predictors of HCC were assessed with a Cox regression analysis. After a median follow‐up of 10.7 years, 44 [4.26/100/year, confidence interval (CI) = 3.11–5.68/100/year] of 104 patients infected with genotype 1b developed HCC versus 10 (1.69/100/year, CI = 0.82–3.09/100/year) of 52 patients infected with genotype 2a/c (P = 0.0001). Multivariate analysis showed that HCV genotype 1b was independently associated with HCC development [hazard ratio (HR) = 3.02, 95% CI = 1.40–6.53]. Other predictors of HCC were esophageal varices (HR = 2.15, 95% CI = 1.03–4.47), male gender (HR = 2.12, 95% CI = 1.10–4.11), and age over 60 years (HR = 5.96, 95% CI = 1.23–28.8). Conclusion: HCV genotype 1b is associated with a statistically significant higher risk of developing HCC. Patients with cirrhosis that are infected with this genotype require more intensive surveillance for the early detection and aggressive management of neoplasia. (HEPATOLOGY 2007.)
|
2022-12-29T17:26:53.590Z
|
243,746,204 |
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"DOI": "10.31219/osf.io/9bcxk",
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}
|
One of biomedicine's most popular uses of Carbon Nanotubes (CNTs) is drug/gene delivery. CNT may carry drugs such as docetaxel (DTX), doxorubicin (DOX), methotrexate (MTX), paclitaxel (PTX), and gemcitabine (GEM). The human body has not yet assessed CNTS and its use in therapeutic applications is still in its early stages. Carbon nanotubes' intrinsic properties have spurred a flurry of research endeavors. Before using them in therapeutic applications, a full knowledge of their pharmacological and toxicological features is required." In recent decades, nanomaterials have attracted interest from scientists, maybe more than any other material type. In recent years, nanomedicines have grown in popularity. Nanomedicine has been popularized in recent years. It has become one of research's fastest-growing fields. Researchers have tried to use carbon nanotubes as possible candidates for various biological applications. They can be swallowed to deliver medicines and genes through passive or active absorption mechanisms. Cell internalization of CNTs is a complicated process that can have both beneficial and negative repercussions. Despite recent breakthroughs in nanotoxicology, scientists have been unable to anticipate carbon nanotubes' behavior and biokinetics precisely. There is still a need to assuage anxieties about the possible harmful effects of C NT applications in medicine, and we must all work together to conduct better studies to provide conclusive answers, experts say. Benefits and disadvantages should be evaluated against those of other drug delivery methods, since each has its own pros and downsides.
|
2022-01-27T03:45:23.301Z
|
85,761,868 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/JSFA.3378",
"MAG": "2121271643",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The dough rheological behaviors of three flours having different chemical and physical properties were measured, as were changes in thickness and snapback (thickness of the machined dough sheet relative to the roll gap), immediately following sheeting. Dough snapback was determined to be a function of processing parameters, reduction ratio, and dough rest time, as well as different flour properties. The predication equation for dough snapback is based on multiple flour properties and sheeting conditions. Higher protein flours normally have stronger dough properties and larger snapback, compared with low protein flours, but also depend on the protein quality. The snapback will increase either with increased protein content, reduction ratio, or reduced rest time. Dough snapback using flour made by blending two flours 50/50 had intermediate values between the two original flours. Among the variables, Mixograph work, reduction ratio, and dough rest time were the main factors affecting the elastic characteristics of the doughs. Minimum snapback occurred with the weakest flour experiencing the longest rest time and the smallest reduction ratio. A linear 7-factor equation was found to predict the snapback of several flours, by combining reduction ratio, dough rest time, Mixograph work, peak height, and mixing time, Alveograph P/L, and protein content. Only three factor combinations of Mixograph work, reduction ratio, and rest time were needed to develop a second order equation for predicting snapback. Copyright © 2008 Society of Chemical Industry
|
2022-02-10T23:03:15.938Z
|
248,595,759 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1108/prt-02-2022-0018",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Purpose
The purpose of this study is to find an applicable solution for the consolidation of petrified paper after disassembling it to complete other stages of treatment.
Design/methodology/approach
The samples were subjected to natural aging by being inoculated with Aspergillus niger until they reached the stage of adhesion and petrification. After that, the leaves were separated, and cellulose nanocrystals were applied, then the leaves were subjected to wet thermal aging for 21 days. Digital microscope, scanning electron microscope, mechanical properties measurement, measurement of color change, Fourier transform infrared spectroscopy and pH measurement were used to evaluate the effects of the cellulose nanocrystal on paper.
Findings
The results proved that cellulose nanocrystal (5%) successes consolidation of petrified paper Without affecting its natural, mechanical and chemical properties.
Originality/value
This study was based on the effectiveness of cellulose nanocrystal in strengthening the petrified papers and testing its effect on the physical, mechanical and chemical paper properties.
|
2022-05-10T19:19:31.596Z
|
86,565,479 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1182/BLOOD-2018-99-119118",
"MAG": "2912012014",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Introduction: Studies of various solid tumors have suggested a potential for statins to modify cancer risks/outcomes. Statins can induce apoptosis and inhibit JAK2-V617F-dependent cell growth in vitro, as well as inhibit erythropoietin-independent erythroid colony formation of primary cells from patients with myeloproliferative neoplasms. JAK2-V617F mutation occurs in about 60% of patients with essential thrombocythemia (ET). It is unknown whether the use of statins influences the outcomes of ET patients.
Methods: Using the Surveillance, Epidemiology, and End Results-Medicare linked database, we assembled a population-based cohort of older adults who were diagnosed with ET during 2007-2013 and fulfilled the following eligibility criteria: 1) aged 66-99 years at diagnosis; 2) had continuous Medicare Parts A and B coverage and not enrolled in health maintenance organizations from 12 months before diagnosis to death or the end of study (12/31/2014), whichever was earlier (i.e., the end of follow up); and 3) continuously enrolled in Medicare Part D from 6 months before diagnosis to end of follow up. Patients were identified as statin users if they had any prescription for statins (rosuvastatin, atorvastatin, pitavastatin, simvastatin, lovastatin, pravastatin, or fluvastatin) in Part D claims from their ET diagnosis to end of follow up. For both statins and hydroxyurea (HU, a commonly used treatment for ET), percentage of days covered (PDC) was defined as the percentage of days from diagnosis to the end of follow-up covered by respective prescriptions. We further classifed statins as lipophilic (atorvastatin, lovastatin, simvastatin, pitavastatin and fluvastatin) or hydrophilic (pravastatin and rosuvastatin).
Log-rank tests were used to compare Kaplan-Meier (K-M) curves between statin users and non-users with regard to overall survival and risk of thrombosis after ET diagnosis. Multivariate Cox proportional hazards models were used to assess the relationship between statin PDC and overall survival. Multivariate competing risk models with death as a competing risk were utilized to evaluate the relationship between statin PDC and risk of thrombosis after ET diagnosis. All multivariate models adjusted for HU PDC, age, sex, race, state buy-in, influenza vaccination 12 months prior to ET diagnosis (as a marker for healthcare access), disability status, modified Elixhauser score for comorbidities, and previous thrombosis. All statistical tests were two-sided and conducted with SAS (Version 9.4).
Results: Of the 876 ET patients included in this study (median age = 78 years, interquartile range [IQR]: 72-84 years), a majority were female (67.8%) and white (86.4%) (Table 1). Approximately half of the patients (n=412, 50.5 %) used statins after ET diagnosis with a median statin PDC of 56% (IQR: 24%-87%). Of the 412 statin users, 75.8% (n=335) already used statins before ET diagnosis; 306, 76, and 60 patients used exclusively lipophilic statins, exclusively hydrophilic statins, and both types, respectively.
With a median follow-up of 2.79 years, 35.8% (n=158) of statin users and 48.2% (n=209) of non-users died; K-M curves showed that statin users (median: 6.01 years) had a significantly better overall survival than non-users (median: 4.00 years; Log rank test, p<.01) (Figure 1). Adjusting for covariates, every 10% of statin PDC after ET diagnosis was associated with a 14% lower risk of all-cause mortality (hazard ratio [HR]=0.86, 95% confidence interval [CI]: 0.82-0.89; p<.01). Increases in lipophilic and hydrophilic statin PDC had similarly positive effects on overall survival.
Thrombosis after diagnosis was recorded in 301 (34.4%) patients, including 230 arterial thromboses. The percentages of statin users and non-users who had thrombosis were similar (33.8% vs. 34.8%). Risk of thromosis was not significantly different between statin users and non-users based on Log-rank test (p=.27) or multivariate competing risk model (p=.68) (Figure 2). No association with thrombosis was observed in users of lipophilic or hydrophilic statins.
Sensitivity analyses that only included patients who started using statins after ET diagnosis revealed similar findings pertaining to both survival and thrombosis.
Conclusions: In this large population-based cohort study of older adults with ET, use of statins improved patient survival but did not have significant impact on incidence of thrombosis.
Podoltsev: CTI biopharma: Research Funding; Astellas Pharma: Research Funding; Pfizer: Consultancy, Honoraria, Research Funding; Alexion: Consultancy, Honoraria; Daiichi Sankyo: Research Funding; Sunesis Pharmaceuticals: Research Funding; Boehringer Ingelheim: Research Funding; Astex Pharmaceuticals: Research Funding; Celgene: Research Funding; Celator: Research Funding. Zeidan:Agios: Consultancy, Honoraria; Otsuka: Consultancy, Honoraria; Takeda: Honoraria, Speakers Bureau; Novartis: Consultancy, Honoraria; AbbVie: Consultancy, Honoraria; Celgene: Consultancy, Honoraria; Pfizer: Consultancy, Honoraria. Huntington:Janssen: Consultancy; Celgene: Consultancy; Bayer: Consultancy. Davidoff:Celgene: Research Funding. Gore:Celgene: Consultancy, Research Funding. Ma:Celgene: Consultancy, Research Funding; Incyte: Consultancy.
|
2022-06-24T17:38:23.976Z
|
236,395,790 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1093/CDN/NZAB036_026",
"MAG": "3171137207",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Epidemiologic evidence for specific types and sources of dietary fat and individual fatty acid with colorectal cancer (CRC) risk remains inconclusive. We aimed to comprehensively examine the associations of intake of specific types (saturated-, monounsaturated-, polyunsaturated-, and trans-) and sources (animal-, dairy-, and vegetable-) of dietary fat and fatty acids with CRC risk.
We prospectively followed-up 65,550 women from the Nurses’ Health Study (1986–2014) and 45,684 men from the Health Professionals Follow-up Study (1986–2014). Dietary intake was assessed every 4 years using food frequency questionnaires. Self-reported CRC cases were confirmed through medical record review. Time-dependent Cox proportional hazards regression was used to estimate the HR for intakes of dietary fat and fatty acids and CRC risk.
During 2,705,560 person-years of follow-up, 2726 incident CRC cases were confirmed. Intake of monounsaturated fatty acid (MUFA) tended to be positively associated with the risk of CRC (HR comparing extreme quintiles 1.21; 95% CI 1.00, 1.47; P = 0.06 for trend) compared with total carbohydrates. This positive association was mainly driven by MUFA from animal sources (MUFA-As) (HR 1.25; 95% CI 1.02, 1.53; P = 0.02 for trend). The positive association between MUFA-As and CRC was attenuated after adjusting for red and processed meat consumption (HR 1.17; 95% CI 0.94, 1.46). Other types and sources of fat intake and individual fatty acid intake were not associated with CRC risk. Isocalorically replacing MUFA-As with equivalent energy (5%) from carbohydrates from whole grains was associated with a trend towards a lower risk of CRC (HR 0.88; 95% CI 0.77, 1.01).
Higher intake of MUFA-As was associated with higher CRC risk compared with total carbohydrates or carbohydrates from whole grains, possibly due to other components of animal-sourced foods. We did not find clear associations between other types and sources of dietary fat and CRC risk.
National Institutes of Health (UM1 CA186107, P01 CA87969, and U01 CA167552)
|
2022-08-18T18:11:55.623Z
|
85,130,326 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S0024282989000381",
"MAG": "2075638001",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Lichen Society were submitting records for the Society's Distribution Maps Scheme on a regular basis, commonly making intensive inventories of several 10 x 10 km grid squares. The editors of the book have also done a very good job. There are almost no printer's errors, and the editors have apparently contributed to the fact that the lists of references are extremely useful, showing that skilful literature scanning is a very essential part of contemporary scientific research. All contributions are of general interest even for those who are just teaching lichenology. The purchase of this volume can therefore be recommended, even though it is also available in the Botanical Journal of the Linnean Society.
|
2022-09-15T06:33:06.904Z
|
252,630,020 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.18280/ria.360404",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://www.iieta.org/download/file/fid/82134"
}
|
The selection of the best spectrum band available to meet the quality of service requirements of secondary users without interfering with the transmission of the primary users is considered as a challenge in cognitive radio networks. On the other side, green network is a recent concept that refers to the processes used to optimize a network in order to make it more energy efficient. In this paper, we propose a new algorithm ensuring the selection of the best available spectrum satisfying the demands of the secondary users based on TOPSIS and AHP in OFDM-based cognitive radio networks. We will assess the need for the secondary users in terms of quality of service and energy efficiency, by analyzing the characteristics of the available channels and taking into account the interference generated with the presence of the primary user. It efficiently manages energy because it allows a significant reduction of the transmission power used by the secondary user and therefore presents an effective solution in green networking.
|
2022-10-07T00:28:57.020Z
|
229,521,372 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/oso/9780198862437.003.0016",
"MAG": "3107671372",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In the context of the country’s widespread HIV/AIDS epidemic, young Congolese women and men take remarkable risks in their sex lives. They do so aware of what Western biomedicine has shown about modes of AIDS infection and necessary protection against it. This chapter documents and explains the central problem that local risk behaviour raises: how can there be such a gap, in this life-and-death matter, between the awareness of risk and actual behaviour? The chapter argues that several factors are at play: their experience of condom use and other appropriate or inappropriate preventative behaviour in light of prevailing, accepted ideas of the body and sexuality; the main forms of sexual relationships in light of Congolese gender and age relations, combined with the powerful influence of relative poverty; their distrust of national and clinical institutions; and the role of religion and traditional healing practices that speak directly to young people’s understanding and experience of their sexuality and vulnerability. The findings do not provide a formal model of risk which effectively displaces the concepts of rational choice in preventing infection that prevail in clinical programmes. They do, however, show very powerfully that young people act in alignment with reasons that make good sense, given the limited options available to them.
|
2022-01-27T01:30:58.475Z
|
227,770,394 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3760/CMA.J.ISSN.1672-7088.2010.03.091",
"MAG": "3029462950",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
目的 探讨改良会阴缝合法的临床应用效果及护理方法.方法 将110例自然分娩行会阴左侧切开缝合的产妇随机分为改良组和传统组各55例,会阴切口分别采用无损伤可吸收线连续不打结皮内缝合法和常规丝线间断皮外缝合法,比较2组切口愈合情况.结果 改良组采用的无损伤可吸收线连续不打结皮内缝合法在促进切口愈合方面明显优于传统组的常规丝线间断皮外缝合法.结论 改良会阴皮内缝合,具有术后切口反应轻,产妇痛苦小,不需拆线,住院时间短等优点,加强护理可提高疗效。
|
2022-01-27T04:51:38.829Z
|
235,839,648 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.29122/JEL.V16I1.4581",
"MAG": "3158928132",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Indonesia has various types of energy sources, either from conventional energy sources or from newand renewable energy sources. Currently, Indonesia has a program to construct of 35 GW of coal-firedpower plant, as well as an intensive development of Geothermal power plant, since it's reserve isabundant. The construction of these types of power plants has a potency to increase Green House Gas(GHG) production, and therefore it necessarily needs to be anticipated. In 2018, there was 543 millionton of CO2 produced in Indonesia and about a half sourced from power generation sectors. Referring tothe ratio of 1 to 1.5 of CO2 converted with the process of hydrogenation, this indicates a promisingamount of methanol can be obtained. However, there are some challenges need to be overcome toachieve this beneficiary. This paper encloses a description of each challenge, with the main descriptionis on the potency of implementation in Indonesia. Some models from existing development aredescribed, to identify the process of development. This information can be used as a consideration forthe implementation in Indonesia.Keywords: CO2 utilization, Metanol formation, Hydrogen, Green House Gas, Geothermal power plant,Gas power plant
|
2022-01-27T12:00:33.281Z
|
78,960,756 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1182/BLOOD.V118.21.4856.4856",
"MAG": "2560414316",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract 4856 Introduction: Diamond Blackfan Anemia (DBA) is a rare congenital, bone marrow failure syndrome characterized by normochromic macrocytic anemia, reticulocytopenia and absence or insufficiency of erythroid precursors in normocellular bone marrow. Thirty to 40 percent of patients display also other somatic malformations. DBA affects 5–7 subjects per million live births and in ∼ 90% of the cases the diagnosis is made in infancy or early childhood. Thus, in Greece with a population number of around 10×10 6 inhabitants, around 30–40 patients are expected. The disease is most commonly sporadic, but it can also be inherited as an autosomal dominant trait with incomplete penetrance. Heterozygous mutations in 9 ribosomal proteins genes have been reported in 50% of patients. Epidemiological studies in different populations showed that the most commonly affected genes are the RPS19 (with a reported frequency of 11–28%), the RPL5 (with a frequency of 9–21.4%) and the RPL11 (with a frequency of 4–9.3%). Aim: The primary aim of this analysis is to assess the incidence of mutations in the RPL11 gene in Greek patients with DBA. τhis analysis is to complement the evaluation of the clinical and hematologic phenotype, as well as, the incidence of mutations in the RPS19 and RPL5 genes in these patients. Furthermore, the diagnostic value of Enzymatic Cleavage Mismatch Analysis (ECMA) in respect to the study of DBA was, also, assessed. Methods: A questionnaire requesting data on clinical and hematological phenotype was sent to all the pediatric hematology, hematology and transfusion units in Greece. Informed consent was obtained from all patients and/or their family members participating in this study and genomic DNA was isolated from peripheral blood lymphocytes. PCR primers were specifically designed to amplify the whole coding region and the flanking intron/exon junctions of RPS19, RPL5 and RPL11 genes. RPS19, which bares the highest rate of mutations, was studied by both ECMA and direct sequencing. RPL5 and RPL11 genes were initially studied by ECMA. Direct sequencing was performed only in the samples that ECMA indicated the existence of a possible mutation. Results: Seventeen Greek patients, comprising 7 females and 10 males, with a mean age of 11.4±11 years, were referred for DBA molecular analysis. Congenital anomalies in different organs, including craniofacial, upper extremities, hands, eyes, heart and kidneys were observed in 66.7% of the patients. In regard to the clinical course, 4 patients were receiving chronic steroid therapy and 8 were on regular transfusions. One of the 8 transfusion-dependent patient developed thyroid cancer at the age of 46 years. One patient died from complications following bone marrow transplantation from an HLA-matched unrelated donor. Spontaneous resolution of the anemia was observed in one patient, one year after she had been referred, making the diagnosis of DBA on this patient questionable. The three remaining patients were lost to follow up. As previously shown (Delaporta P et al.; Haematologica, 2011; 96(s2):345a) , 6 patients (35.2%) were found to carry mutations on either the RPS19 gene (3 patients,) or the RPL5 gene (3 patients). Mutations c.C390G (p.9130X) and c.197_198insA (p.Y66X) detected in the RPL5 gene were novel. All the mutations in the RPS19 gene were identified by both ECMA and direct sequencing. Further molecular analysis on the RPL11 gene did not disclose any mutations on the six exons of the gene. Nevertheless, the molecular analysis revealed the previously described c.507+39 A>G variant in intron 5 (2 patients) and a novel c.264+49 A>G variant in intron 3 (1 patient). Conclusions: Based on the reported frequency of RPL11 gene in previous population studies around the world, we would expect to identify 1–2 positive samples. No mutations at the RPL11 gene were revealed in Greek patients with DBA, but this may be due to the small sample size. Higher frequency of physical malformations and rates of transfusion dependency was observed compared to the ones reported from other countries. Finally, the consistency of the results between ECMA and direct sequencing support the high diagnostic value of the ECMA method in evaluating patients with DBA. Disclosures: No relevant conflicts of interest to declare.
|
2022-02-11T04:19:03.211Z
|
10,840,770 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1155/2013/679724",
"MAG": "2054234261",
"PubMedCentral": "3777119"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://downloads.hindawi.com/archive/2013/679724.pdf"
}
|
Background and Aims. Villin is a highly specialised protein and is expressed in intestinal and renal proximal tubular epithelium. It was detected in colorectal carcinomas (CRC) and other nongastrointestinal tumours. The aim of the current study is to investigate the immunohistochemical expression of villin in a subset of primary CRC and determine its relation to tumour differentiation, invasion, nodal metastasis, recurrence, and disease-free survival. Patients and Methods. Paraffin blocks of 93 cases of CRC were retrieved constituting 93 primary CRC and 58 adjacent normal mucosa. Immunohistochemistry was performed using antivillin antibody. The extent (%) of villin immunoexpression was categorised for statistical analysis. Statistical tests were used to determine the association of villin with clinicopathological characteristics: age, sex, tumour location, tumour size, depth of invasion, tumour grade, nodal metastasis, lymphovascular invasion, margin status, recurrence, and survival. Results. Villin immunostaining results showed that villin is downregulated in CRC. Villin has no association with age, sex, tumour location, depth of invasion, nodal metastasis, lymphovascular invasion, margin status, and recurrence. However, villin is expressed in higher rate in CRC less than 5 cm, well- and moderately differentiated CRC. Poor survival was associated with tumour with low villin immunoexpression. Conclusion. Villin was downregulated in CRC. Villin immunoexpression in CRC is associated with better survival, well-differentiated tumours, and small-sized tumours. Villin has no significant association with disease recurrence or nodal metastasis. More in vivo and in vitro studies are required for further elucidation of how villin may be involved in CRC.
|
2022-10-11T18:46:45.298Z
|
252,519,655 |
{
"externalids": {
"ACL": null,
"ArXiv": "2209.11526",
"DOI": "10.48550/arXiv.2209.11526",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
—Plants are dynamic organisms. Understanding temporal variations in vegetation is an essential problem for all robots in the wild. However, associating repeated 3D scans of plants across time is challenging. A key step in this process is re-identifying and tracking the same individual plant components over time. Previously, this has been achieved by comparing their global spatial or topological location. In this work, we demonstrate how using shape features improves temporal organ matching. We present a landmark-free shape compression algorithm, which allows for the extraction of 3D shape features of leaves, characterises leaf shape and curvature efficiently in few parameters, and makes the association of individual leaves in feature space possible. The approach combines 3D contour extraction and further compression using Principal Component Analysis ( PCA ) to produce a shape space encoding, which is entirely learned from data and retains information about edge contours and 3D curvature. Our evaluation on temporal scan sequences of tomato plants shows, that incorporating shape features improves temporal leaf-matching. A combination of shape, location, and rotation information proves most informative for recognition of leaves over time and yields a true positive rate of 75%, a 15% improvement on sate-of-the-art methods. This is essential for robotic crop monitoring, which enables whole- of-lifecycle phenotyping.
|
2022-09-29T13:32:11.054Z
|
172,036,952 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4000/LEXIS.2453",
"MAG": "2903707987",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Cet article presente l’analyse semantique et la diffusion de neologismes genres en anglais que l’on appellera « man-neologisms » tels que man bun, mancation (man + vacation) et manspread. Notre etude (basee sur Foubert [2018]) montre que l’usage de man dans ces neologismes ne se refere que tres peu a son sens generique (les etres humains en general, comme dans Homme) mais se refere plutot au sens specifique (homme). Notre analyse semantique des neologismes avec ce sens specifique montre qu’ils sont specifiques par le fait qu’ils designent majoritairement des domaines typiquement associes aux femmes. De plus, notre etude revele quatre motivations a l’origine de ces neologismes : (i) se reapproprier des domaines typiquement associes aux femmes, tel que man purse (un sac a main pour les hommes), (ii) cultiver les differences, tel que man cave (une piece reservee aux hommes), (iii) conforter les stereotypes, tel que man science (des connaissances qui ne sont disponibles qu’aux hommes), et (iv) nommer des comportements masculins indesirables, en ayant pour but de les changer, tel que mansplain (man + explain, ou mecspliquer : quand un homme explique quelque chose de facon condescendante). L’analyse portant sur la diffusion etudie la frequence des occurrences des neologismes ; les resultats montrent que les neologismes qui visent a se reapproprier des domaines et plus particulierement ceux qui visent a nommer des comportements masculins sont numeriquement peu representes dans les formations nouvelles, mais utilises frequemment, a l’inverse des neologismes qui cultivent les differences et confortent les stereotypes.
|
2022-10-07T00:47:53.582Z
|
91,044,529 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/jpa.2016.156",
"MAG": "2581538284",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://www.cambridge.org/core/services/aop-cambridge-core/content/view/73055C09B556970C70FCB9ADAD781FA3/S0022336016001566a.pdf/div-class-title-new-taxa-and-phyletic-evolution-of-the-aeronian-llandovery-silurian-petalocrinidae-echinodermata-crinoidea-in-guizhou-south-china-block-div.pdf"
}
|
Abstract.
Systematic paleontology of three new species of Petalocrinidae (Crinoidea) are documented from the carbonate-dominated units of the Shihniulan and equivalent Leijiatun formations (Llandovery, Silurian) of the Baisha, Fengxiang, and Shuibatang sections in Guizhou (China). New taxa are from the Upper Yangtze Epicontinental Sea of the South China Block. The new taxa include Petalocrinus stenopetalus new species, Spirocrinus circularis new species, and S. dextrosus new species. They have a narrow spatial and temporal (Aeronian) distribution. Evolutionary patterns of the four genera of Petalocrinidae are outlined based on the specialized characters of the fused arm plates. Phylogenetic analysis was used to assess morphological relationships within the Petalocrinidae. Petalocrinus inferior represents the plesiomorphic condition for the group and nests as a sister group of P. stenopetalus n. sp. and the Spirocrinus species used in this analysis and the clade exclusively comprised of Sinopetalocrinus. The phylogenetic analysis suggests that Petalocrinus, as currently defined, might be a paraphyletic genus.
|
2022-11-19T18:02:01.960Z
|
191,358,749 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2307/834475",
"MAG": "2318694166",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Le propos de cet article est de retracer les principales periodes de developpement des diverses pratiques conventionnelles de l'ensemble musical arabe Rashidiyya depuis sa fondation jusqu'a l'epoque actuelle. Cet ensemble musical a apporte d'importantes innovations au style musical ma'luf en Tunisie et a influence diverses pratiques musicales en Egypte. Finalement une comparaison entre l'ensemble Rashidiyya et les pionniers de ce genre musical quarante annees auparavant, L'ensemble de Musique Arabe du Caire, permet d'analyser les differences historiques entre les cultures musicales urbaines tunisienne et egyptienne, et plus specifiquement le concept et la signification du al-turath pour chacun de ces cas.
|
2022-12-14T17:30:14.714Z
|
96,553,409 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/JP0754987",
"MAG": "2094233935",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A systematic density functional study of the adsorption and dissociation of O2 on the (001) surface of several transition metal carbides (TCMs; TM = Ti, Zr, Hf, V, Nb, Ta, Mo) is presented. It is found that O2 may adsorb molecularly on two different sites with similar adsorption energy. At these sites, either O2 bridges two surface metal (M) atoms or it is placed directly on top of a M surface atom. A case apart is δ-MoC, where O2 adsorption on top of surface Mo atoms is far up in energy with respect to bridging two surface Mo atoms. The relative stability of O2 on these TMCs is dominated by the electron back-donation between the surface and O2 and the stabilization of the resulting partially charged molecule by the surface metal sites. Three reaction paths leading to O2 dissociation have been considered. The first reaction pathway starts from M−M bridge molecular adsorption and lead to O atoms on top of surface M atoms (TSM) and the second one (TSC) starts from on top molecular adsorption and lead to fin...
|
2022-12-12T09:30:33.092Z
|
158,127,992 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/0007650317722779",
"MAG": "2751234169",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In Sandra Waddock’s article “Taking Stock of SIM” in this journal, she identifies key issues in the work of the Social Issues in Management (SIM) Division of the Academy of Management. This article challenges her analysis of SIM scholarship and her arguments of what is necessary for the division to progress. Scholarship in SIM should emphasize two key streams: First, scholars in SIM should seek to develop a science of social forensics, design, and social repair—in essence, develop a method of problem diagnosis, an approach to practical solution design, and a systematic understanding of the selection and implementation of social repair—in other words, seek to understand how to systematically troubleshoot and engineer solutions to fundamental issues in the business and society interface. The second stream, which informs the first, involves the development of original, core, transferable systematics that can “travel”—be the source of understanding-generating analysis—in other disciplines, including the topical regions of the Academy of Management. The article argues that laying claim to and developing true normative theory applicable across disciplines should be a distinctive identifier of work in SIM. The article concludes with an illustration of how systematics can be applied to address the literature’s failure to even seek to understand the logic underlying the standard ethical theories. These theories are properly seen as complements rather than substitutes. We need to ask and answer the “fundamental question of business ethics”: What should I do? .We suggest an approach labeled “integrative ethics,” employing ethical frames/injunctive formats, framed contexts for action, and the distribution of desires.
|
2022-12-17T13:30:07.703Z
|
100,853,477 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1515/MGMC.2006.29.1.1",
"MAG": "2318234770",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Reactions of homoleptic glycolate or diethanolaminate complexes of aluminium, Al(OGO)(OGOH) (where G = CHMeCH2CMe2(G') la ; CHMeCHMe(G) lb ; CH2CMe2CH2(G) lc; CMe2CMe2(G) Id) or Al(Rdea)(RdeaH) (where Rdea = RN(CH2CH20")2, RdeaH = RN(CH2CH20") (CH2CH2OH) and R = H, le; Me If; Bu lg; Ph lh), respectively with VO(OPr')3 in 1:1 molar ratio at room temperature afford novel heterobimetallic complexes of the types: Al(OGO)2{VO(OPr)2}(G = G, 2; G ,3; G,4; G, 5) and Al(Rdca)2{VO(OPr')2} (R=H, 6; Me, 7; Bu, 8; Ph, 9). All of these complexes have been characterised by elemental analyses, molecular weight measurements, and spectroscopic studies. Plausible structures have been suggested on the basis of spectral data and molecular weight.
|
2022-01-27T03:27:36.531Z
|
14,939,801 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/56.797",
"MAG": "2129264762",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The dynamic analysis of a three-degrees-of-freedom in-parallel actuated manipulator is presented. The equations of motion have been formulated in joint-space using the Lagrangian approach. The analysis provides the solution to predict the forces required to actuate the links so that the manipulator follows a predetermined trajectory. A dynamic simulation program illustrates the influence of the link dynamics on the actuating force required. An example of tracing a helical path is chosen to illustrate the dynamic simulation and to show that the Cartesian position of the moving platform may be controlled at a sacrifice of orientation freedoms. The dynamic analysis provides a basis for future theoretical research to develop the control scheme, for experimental research to estimate the inertia parameters, and for design optimization of the prototype manipulator. >
|
2022-12-22T04:39:26.847Z
|
233,981,626 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1210/jendso/bvab048.827",
"MAG": null,
"PubMedCentral": "8090033"
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://academic.oup.com/jes/article-pdf/5/Supplement_1/A406/37204830/bvab048.827.pdf"
}
|
Abstract Most associations from genome-wide association studies (GWAS) result from as-yet-unknown alterations of molecular or cellular function; the causal variants and effector genes responsible for them, and the tissues and pathways through which they act, remain largely unknown. Thousands of associated loci have now been identified for each common disease and its related traits. In order to translate GWAS data into biological knowledge, they must be integrated with functional genomic annotations reflecting tissue-specific regulation and with the results of bioinformatic methods that predict the functional effects of associations. However, these data types are typically spread across disparate resources, and working with them requires bioinformatic expertise. To make these results accessible and understandable to the broader diabetes and cardiometabolic disease research communities, we have developed the open-access Common Metabolic Diseases Knowledge Portal (CMDKP; cmdkp.org), which brings together a robust software and data storage platform with a streamlined and intuitive user interface for four disease areas: diabetes (both types 1 and 2); cardiovascular disease; cerebrovascular disease; and sleep and circadian disorders. The CMDKP enables researchers to access and explore a comprehensive matrix of genetic, genomic, and computational results. It includes 3 classes of genomic data: 1) GWAS summary statistics from the most current and authoritative datasets available, as identified by disease-area experts; 2) functional genomic annotations, such as chromatin accessibility, that reflect the tissue-specific regulatory potential of genomic regions; and 3) the results of bioinformatic methods applied to these aggregated data (for example, overlap-aware meta-analysis to determine “bottom-line” p-values, the GREGOR method for determining tissue-specific enrichment of genetic associations, the MAGMA method for generating gene-level association scores, and more). All of these data types are integrated and accessible via interactive tools that allow researchers to explore and evaluate the data in order to identify candidate disease effector genes for further research. The CMDKP provides researchers with the data and tools necessary to translate genetic associations and functional annotations into knowledge about disease mechanisms and potential therapeutic targets.
|
2022-01-27T06:47:36.055Z
|
14,377,587 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CSNDSP16145.2010.5580368",
"MAG": "2113559408",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Recent developments in solid-state light-emitting diode (LED) materials and devices is driving a resurgence into the use of free-space optics (FSO) for wireless broadband communication. This technology uses the visible spectrum provided by “white” LEDs that are becoming ubiquitous in lighting and has some desirable properties competitive with existing radio frequency (RF) communications. By leveraging the low-cost nature of LEDs and lighting units there are many opportunities to exploit this medium for widespread optical communication deployment. The optical medium, however, has particular characteristics, including directionality and susceptibility to noise sources in the visible spectrum that must be managed.
|
2022-12-21T21:06:42.820Z
|
195,756,781 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/exd.13998",
"MAG": "2954719152",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/exd.13998"
}
|
Hair loss, from the vertex or front of the head, generally occurs due to increased androgenic steroid levels. Androgenic steroids, particularly testosterone and dihydrotestosterone, are distributed differently across the vertex and occipital regions and are involved in inducing ornithine decarboxylase expression. Therefore, we hypothesized that the distribution of polyamines may be altered in different scalp regions. For the overall metabolic profiling of polyamines in patients with hair loss, a liquid chromatography‐mass spectrometry was used. We investigated the differential polyamine levels in different regions of the hair of patients with male pattern baldness and those with female pattern hair loss. The levels of most polyamines were higher in the vertex region than in the occipital region, and N‐acetyl polyamine levels differed significantly. We proposed to test our hypothesis by profiling polyamines in human hair fibre to evaluate the distribution of metabolites in various regions of the scalp.
|
2022-12-30T00:24:21.545Z
|
148,629,949 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1192/S0007125000221533",
"MAG": "2790641415",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This book is notable for its breadth of coverage. Clinical self-multilation is studied in depth, and from the broader perspective of cultural psychiatry. It includes a very interesting survey of references to self-mutilation in the literature, in mythology, and in various religious beliefs and practices. Ethological aspects of self-mutilation are dealt with, including the role of biochemical and biological lesions and the occurrence of auto-mutilation in captive ani mals. Interesting observations are made of similarities betw@n animal and human self-mutilating behaviour. The author finds that self-mutilation in mental illness, whatever the diagnosis, involves deliberate destruction or damage to body tissues without a conscious intention of ending life. The self-mutilation can be an isolated or repetitive act ranging from skin cutting or needle sticking to eye mutilation or genital amputation. Self mutilation often serves to reduce symptoms of anxiety and other forms of distress, and may forestall suicideby sacrificing a part for the whole. A detailed description is presented of the specificde liberate self-harm syndrome, together with criteria for assessment and diagnosis which form the basis for a comprehensive plan of treatment; biological, psycho therapeutic, behavioural, and social interventions may be employed, depending on the needs of the particular patient. This book can be warmly recommended as a compre hensive, lucid and interestingly-written book which is likely to become a classic on the subject.
|
2022-02-09T04:47:12.815Z
|
241,504,753 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.37506/ijphrd.v11i4.5398",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
Isoprinosine was approved that it had hepatic and renal disorder in rabbits. This review covers key studies of protective effects of vitamin E (18.7 mg/kg P. O.) against isoprinosine (163.3 mg/kg P. O.) toxicity for 21 days when vitamin E was co-administered with isoprinosine. Blood samples were collected and the protective effect of vitamin E onbiochemical constituents in serum such as liver injury biomarkers as serum ALT, AST and ALP, kidney injury biomarker as serum creatinine and urea and oxidative stress biomarkers such as serum SOD, GPX and MDA. The obtained results indicated that vitamin E has protection effects through prohibiting the raise in liver and kidney injury biomarkers and oxidative stress biomarkers.
|
2022-07-04T19:54:23.700Z
|
21,210,659 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1006/ENRS.1999.4023",
"MAG": "2159190147",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The Chesapeake Bay Program began more than 20 years ago with assessments of a number of key areas, relying on measurements of habitats, plant and animal populations, and physical and chemical conditions. This approach used wildlife as indicators of Bay "health" and of potential threats to human health. The extent of toxic chemical contamination was one of the assessment endpoints in the original survey. When the initial assessment was completed in 1983, the results of Bay-wide surveys indicated that several specific waterways were contaminated. These waters, the Elizabeth River, Virginia, the James River, Virginia, and Baltimore Harbor, Maryland, were targeted for specific actions to address the problems of historical and ongoing pollution. Over the past 10 years or more, data on some toxic chemical releases into and levels in the environment have been collected, but these data are limited in scope. Furthermore, these data are not used to assess threats to human health or more generally to nonhuman endpoints. New and existing data on environmental levels of chemicals and effects at low concentrations provide evidence that toxic chemicals may threaten both human and nonhuman health in the wider Bay system.
|
2022-09-09T14:35:27.478Z
|
51,854,771 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5772/57043",
"MAG": "1495622897",
"PubMedCentral": null
},
"license": "CCBY",
"status": "HYBRID",
"url": "https://www.intechopen.com/citation-pdf-url/45812"
}
|
Zenkovich showed that multiple sand spits with rhythmic shapes may develop in a shallow water body such as the Azov Sea and a lagoon facing Chukchi Sea, as shown in Fig. 1, and called them as the spits of Azov type [1]. Zenkovich concluded that under oblique wave incidence with the angle between the direction normal to the shoreline and the wave direction being larger than 45°, shoreline instability may develop, and during the development of sand spits, the wave-sheltering effect due to the sand spits themselves plays an important role. Ashton et al. [2] adopted this mechanism in their model and successfully modeled this shoreline instability using the upwind scheme in their finite difference method to prevent the numerical instability on the basis of the conventional longshore sand transport formula. Furthermore, this mechanism was called high-angle wave instability in [3]. Littlewood et al. [4] predicted the shoreline of log-spiral bays using their model. Serizawa et al. [5] predicted the development of sand spits and cuspate forelands under oblique wave incidence with the angle between the direction normal to the shoreline and the wave direction being larger than 45°, given a small perturbation in the initial topography, and showed that the three-dimen‐ sional (3-D) beach changes of sand spits and cuspate forelands with rhythmic shapes can be predicted using the BG model (a 3-D model for predicting beach changes based on Bagnold’s concept). Falqués et al. [6] also predicted the development of sand waves caused by high-angle wave instability using equations similar to that of our model, but not the development of sand spits and cuspate forelands protruding offshore. The sand transport equation of the BG model was derived by applying the concept of the equilibrium slope in [7] and the energetics approach of Bagnold [8]. In the fundamental equation of the BG model in [9], the sand transport flux was assumed to be proportional to the wave energy dissipation rate instead of the third power
|
2022-10-28T00:26:33.282Z
|
30,740,420 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1089/END.2006.0279",
"MAG": "2026045368",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Seminal vesicle cysts associated with other genitourologic abnormalities are rare. We describe the first known robot-assisted excision of a cystic seminal vesicle associated with ipsilateral renal agenesis in a symptomatic pediatric patient. The patient was discharged home on postoperative day 1 and remains symptom free after 9 months' follow-up. Operative time, blood loss, and hospital stay were comparable to those of published series of conventional laparoscopy.
|
2022-12-20T17:22:37.665Z
|
144,678,390 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/019263657305736909",
"MAG": "2036787517",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Schools are out of step with the real world by retaining the traditional semester organization of the academic year, the author says, and should adopt the quarter system to be relevant. He discusses several advantages of the quarter system as they relate to demands for accountability.
|
2022-02-09T06:52:54.049Z
|
203,704,869 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1300/J201V05N01_04",
"MAG": "2958963972",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
SUMMARY The second edition of the International Standard Archival Authority Records for Corporate Bodies, Persons, and Families (ISAAR(CPF)2) focuses on describing entities as they exist in reality, rather than on establishing authorized terms. This change allows authority records to include multiple authorized terms representing an entity as it changed over time. Traditionally, an authority record has been created for a corporate body each time its name changed. This practice results in an artificial, fragmented view of the entity, concentrating on heading control rather than on providing contextual information necessary to assist with the provenance-method of retrieval and the interpretation of the records. In order to describe entities as ISAAR(CPF)2 allows and better reflect records-creating environments, the author proposes that an authority record describe a definable unit that performs a distinct function without major temporal interruption.
|
2022-06-14T18:40:07.444Z
|
93,738,288 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/9783527618262.CH8",
"MAG": "1532494235",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This comprehensive manual gives reliable answers to all questions on enzyme catalysis - from searching for suitable catalytic converter systems via choosing the optimal reaction conditions to implementing modern synthesis strategies.
|
2022-10-19T16:33:40.692Z
|
53,837,287 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S004393390700133X",
"MAG": "2041325695",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In chickens and in animals in general, growth is influenced by genotype as well as by environmental factors including nutrition. Hormonal changes form, in part, the causal link between these interacting factors and the physiological processes leading to growth. It is well established that growth-related hormones (GH, SS) play different roles in different tissues. Several studies have investigated the nutritional and/or genetic effects on growth in chickens, leading to the general conclusion that the improvement of growth in modern broiler chickens is largely influenced by the genotype. In addition, it has been shown that the nutrition-determined regulation of tissues is also genotype-specific. Besides growth, genotype-nutrition interactions also influence reproductive parameters (sexual maturation, egg production) and their endocrine control (hormone levels), apparently having long lasting (or epigenetic) effects for the entire lifespan. Especially for broiler breeders, these interactions are of importance in terms of a long-term solution for the broiler breeder paradox. Indeed, broiler breeders need the genetics for rapid growth and yet have to show a high rate of egg production, in spite of the long recognized negative relation between growth and reproductive fitness. Currently, restricted feeding is the only practical tool available to obtain an optimal equilibrium between growth and reproduction. This has the potential for the impairment of welfare (hunger, behaviour, health, viability). Recent studies suggest that modifying the timing of restriction programmes, the quantity/quality of the diet or the use of genotypes that tolerate ad libitum feeding may achieve a good balance between growth and reproductive performance on the one hand and breeder welfare on the other.
|
2022-12-15T22:58:50.357Z
|
13,831,847 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1590/s0104-59702018000100010",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "http://www.scielo.br/pdf/hcsm/v25n1/0104-5970-hcsm-25-01-0163.pdf"
}
|
Augusto dos Anjos, from Paraíba, Brazil, occupies a singular place in Brazilian literature, defying alignment with any one literary style. His poetry is marked by anguished verse, by existential dimensions and a vocabulary replete with scientific terms. His work is of great interest to neuropsychiatry, not just for the abundance of related terms, but also because it reflects conceptions from neuroscience at the turn of the twentieth century. This study focuses on his literary output from a dual perspective: by identifying how his poetry reflects the organicist tendency in psychiatry at the time, as generally personified in the figure of Emil Kraepelin, and by exploring the ideological content of the work, like the Darwinist perspective and the tension between dualism and materialistic monism.
|
2022-12-23T02:26:23.990Z
|
118,450,237 |
{
"externalids": {
"ACL": null,
"ArXiv": "1608.06812",
"DOI": "10.1093/mnras/stw2159",
"MAG": "2507261706",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "http://arxiv.org/pdf/1608.06812"
}
|
Radio polarisation images of the jets of Active Galactic Nuclei (AGN) can provide a deep insight into the launching and collimation mechanisms of relativistic jets. However, even at VLBI scales, resolution is often a limiting factor in the conclusions that can be drawn from observations. The Maximum Entropy Method (MEM) is a deconvolution algorithm that can outperform the more common CLEAN algorithm in many cases, particularly when investigating structures present on scales comparable to or smaller than the nominal beam size with "super-resolution". A new implementation of the MEM suitable for single- or multiple-wavelength VLBI polarisation observations has been developed and is described here. Monte Carlo simulations comparing the performances of CLEAN and MEM at reconstructing the properties of model images are presented; these demonstrate the enhanced reliability of MEM over CLEAN when images of the fractional polarisation and polarisation angle are constructed using convolving beams that are appreciably smaller than the full CLEAN beam. The results of using this new MEM software to image VLBA observations of the AGN 0716+714 at six different wavelengths are presented, and compared to corresponding maps obtained with CLEAN. MEM and CLEAN maps of Stokes $I$, the polarised flux, the fractional polarisation and the polarisation angle are compared for convolving beams ranging from the full CLEAN beam down to a beam one-third of this size. MEM's ability to provide more trustworthy polarisation imaging than a standard CLEAN-based deconvolution when convolving beams appreciably smaller than the full CLEAN beam are used is discussed.
|
2022-12-23T11:45:17.852Z
|
118,015,405 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1063/1.2435295",
"MAG": "1544753869",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The two competing B‐factories (KEKB and PEPII) are performing spectacularly well and the experiments they host (Belle and BaBar), have harvested an impressive amount of data. CP violation in B‐physics has been established and it has become a precision measurement. It is time to look at the future development of the field with special attention to the e+e− option at very high luminosity.
|
2022-12-26T05:30:23.195Z
|
58,933,514 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1051/FOREST:2003003",
"MAG": "1986346752",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
L'apparentement genetique entre paires d'arbres a ete analyse dans une parcelle de pins maritimes adultes dotee d'une regeneration naturelle abondante et avancee, en utilisant trois marqueurs microsatellites tres polymorphes (probabilites d'exclusion > 90 %). Seuls cinq descendants issus d'autofecondations probables ont pu etre detectes, indiquant un taux maximum d'autofecondation de 3,8 %. Des rapports de vraisemblance ont ete utilises pour detecter les relations d'apparentement chez les arbres adultes et dans la regeneration naturelle. Les pourcentages de demi- et de pleins-freres observes parmi les arbres adultes ont ete estimes a 19,09 et 1,82 %,respectivement, indiquant ainsi un faible taux d'apparentement genetique du aux fratries ( 3 %). Des resultats similaires ont ete obtenus pour la regeneration naturelle, mais avec un pourcentage de pleins-freres plus eleve (2,37 %) et des tailles de familles superieures. Un flux de pollen eleve provenant de l'exterieur de la parcelle doit pouvoir expliquer le faible apparentement observe. La recolte de lots de graines dans cette parcelle semble adequate puisqu'un faible taux d'autofecondation y est attendu.
|
2022-12-27T20:04:56.652Z
|
186,685,692 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.24144/2415-8038.1998.3.38-43",
"MAG": "2811261600",
"PubMedCentral": null
},
"license": "CCBY",
"status": "HYBRID",
"url": "https://doi.org/10.24144/2415-8038.1998.3.38-43"
}
|
The result on the activation levels of 109 47 Ag 62 , 115 49 In 66 , 111 48 Cd 63 nuclei observed in (y,y') m reaction along with the data concerning one-nucleon transfer reaction, are analyzed. The shell configurations of transitions from 109 47 Ag 62 , 115 49 In 66 , 111 48 Cd 63 nuclei ground state to the activation levels, corresponding to one-nuclcon transitions between the subshells within the upper unfilled 2plflg- and Ig2d3slh-shell, are determined.
|
2022-08-20T18:10:32.194Z
|
31,880,891 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/NHH.0b013e31821fe9f7",
"MAG": "2009112221",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
High levels of depressive symptoms are common and contribute to poorer clinical outcomes even in geriatric patients who are already taking antidepressant medication. The Depression CARE for PATients at Home intervention was designed for managing depression as part of ongoing care for medical and surgical patients. The intervention provides home health agencies the resources needed to implement depression care management as part of routine clinical practice.
|
2022-09-10T10:33:44.529Z
|
21,501,149 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1249/00005768-199512000-00004",
"MAG": "2091710395",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Despite extensive study of left ventricular (LV) function during incremental exercise (INC), there is little known about LV function during steady state exercise typical of that used during exercise training. In this study we evaluated LV ejection fraction (LVEF) during upright cycle ergometer exercise using first-pass radionuclide angiography (RNA). Healthy volunteers (N = 10) were studied during both INC and steady state. INC studies were performed at rest, at the ventilatory threshold (VT), and at maximal exercise. During steady state studies were performed after 10, 20, and 30 min of exercise at VT. During INC LVEF increased from rest (61% +/- 5%) to exercise at the VT (73% +/- 5%). There was no further change in LVEF at maximal exercise (73% +/- 5%). During steady state, LVEF increased from rest (61% +/- 5%), to exercise at VT (73% +/- 5%), with further increases after 20 (78% +/- 6%) and 30 (79% +/- 3%) min of exercise. The results suggest that LVEF is nearly maximal during submaximal exercise at VT. During steady state LVEF continues to increase with continuation of steady state exercise.
|
2022-09-12T10:27:33.583Z
|
86,821,952 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.23925/2176-901X.2014V17I4P141-155",
"MAG": "1801276940",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The study aimed to identify and update the knowledge about older people with Down Syndrome (DS), and to understand the peculiarities of the aging process in this population. Bibliographical research conducted by Portal de Periodicos da Coordenacao de Aperfeicoamento de Pessoal de Nivel Superior and High Wire portal. Inclusion criteria were articles published in the last ten years with the words “Down Syndrome" and “Elderly”.
|
2022-09-13T04:04:49.721Z
|
82,631,544 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1096/fasebj.23.1_supplement.491.3",
"MAG": "196553905",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
Preferential metastasis of human prostate cancer cells to bone marrow contributes to disease mortality and morbidity. MicroRNAs (miRNAs) are endogenous ~22nt RNAs that play important regulatory roles in animals and plants by binding to specific messenger RNA (mRNA) targets to either block their translation or trigger their degradation. Accumulating evidence indicates that miRNAs are involved in human cancer. Here we used the human prostate cancer cell line, LNCaP, and its derivative bone metastatic subline, C4‐2B, as a model system to study the roles of miRNAs in prostate cancer progression. We sequenced more than two million small RNAs from LNCaP and C4‐2B cell lines using a 454 library. Known miRNAs and new small candidate miRNAs with expression differences between these two cell lines were selected for analysis. Various bioinformatics tools and gene databases were used to identify potential targets for both novel and known microRNAs. Prostate cancer gene expression microarray data were used to further narrow the prospective target genes for known microRNAs. Biobase (http://bkl.biobase.de/cgi‐bin/bkl/idb/1.0/searchengine/start.cgi) software was used to place these gene targets in relevant cellular pathways. Ongoing studies seek to explore the potential targets of miRNAs involved in these pathways. These data provide us with important information about how miRNAs are involved in prostate cancer including identification of new pathways for modulation of gene expression during progression to bone. Understanding the targets and functions of these miRNAs will translate into new means to inhibit prostate cancer metastasis and growth in bone. (Supported by NCI P01 CA098912 and University of Delaware Science and Engineering Scholars Cancer and Genetics Fellowship.)
|
2022-10-14T00:09:23.848Z
|
206,482,985 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1123/ijspp.2015-0559",
"MAG": "2312378180",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://acuresearchbank.acu.edu.au/download/e15feb2c3aacdb64a2ff94f534e1f9cd4f911a20447f7d1fc62255878a356afc/234316/AM_Delaney_2016_Factors_that_influence_running_intensity_in.pdf"
}
|
BACKGROUND
Rugby league coaches adopt replacement strategies for their interchange players to maximize running intensity; however, it is important to understand the factors that may influence match performance.
PURPOSE
To assess the independent factors affecting running intensity sustained by interchange players during professional rugby league.
METHODS
Global positioning system (GPS) data were collected from all interchanged players (starters and nonstarters) in a professional rugby league squad across 24 matches of a National Rugby League season. A multilevel mixed-model approach was employed to establish the effect of various technical (attacking and defensive involvements), temporal (bout duration, time in possession, etc), and situational (season phase, recovery cycle, etc) factors on the relative distance covered and average metabolic power (Pmet) during competition. Significant effects were standardized using correlation coefficients, and the likelihood of the effect was described using magnitude-based inferences.
RESULTS
Superior intermittent running ability resulted in very likely large increases in both relative distance and Pmet. As the length of a bout increased, both measures of running intensity exhibited a small decrease. There were at least likely small increases in running intensity for matches played after short recovery cycles and against strong opposition. During a bout, the number of collision-based involvements increased running intensity, whereas time in possession and ball time out of play decreased demands.
CONCLUSIONS
These data demonstrate a complex interaction of individual- and match-based factors that require consideration when developing interchange strategies, and the manipulation of training loads during shorter recovery periods and against stronger opponents may be beneficial.
|
2022-12-30T00:34:30.906Z
|
83,613,771 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/1934578X0600100804",
"MAG": "1689210186",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
From an extract of the stem bark of Xymalos monospora, a bis-benzylisoquinoline alkaloid (1), three benzylisoquinoline alkaloids (mollinedine, 1-(p-methoxybenzyl)-6,7-methylenedioxyisoquino-line, doryafranine), and an aporphine alkaloid (N-methyllaurotetanine) were isolated. These compounds were tested for growth inhibitory activity against bloodstream forms of three strains of African trypanosomes. In vitro IC50 values starting from 1.8 μg /mL were obtained.
|
2022-09-23T00:24:48.264Z
|
16,184,240 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5194/BG-6-1519-2009",
"MAG": "2146163014",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract. In-canopy turbulence is a required input to study pollutant cycling and chemistry within plant canopies and to link concentrations and sources. Despite the importance of grasslands worldwide, most previous work has focused on forests and crops. Here, turbulence parameters in a mature agricultural grassland canopy were measured with a combination of a small ultrasonic anemometer, hotwire anemometry and a radon (Rn) tracer technique, as part of a measurement to study ammonia (NH3) exchange with grassland. The measurements are used to derive vertical profiles of basic turbulent parameters, for quadrant-hole analysis of the two-parametric frequency distributions of u'−w' and to derive in-canopy eddy diffusivities as input for models of in-canopy tracer transport. The results are in line with previous measurements on taller canopies, but shows increased decoupling between in-canopy flow and above-canopy turbulence. The comparison of sonic anemometry and Rn measurements implies that Lagrangian time-scales must decrease sharply at the ground, with important implications for estimating the magnitude of ground-level and soil emissions from concentration measurements. Atmospheric stability above and within the canopy has little influence on the standard deviation of vertical wind component inside the canopy. Use of the turbulence parameters in an analytical Lagrangian framework, which is here validated for heat transfer, suggests that measured in-canopy profiles of NH3 are consistent with a ground-level source, presumably from senescent plant parts, which is recaptured by the overlying canopy.
|
2022-12-02T11:22:32.601Z
|
254,670,563 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.17398/2340-2784.44.315",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://revistaiberica.org/index.php/iberica/article/download/621/470"
}
|
Academic reading and writing abilities are prerequisites to success in postgraduate programs. These should be domains of competence in particular for students in applied linguistics, whose studies and future performance as teachers require insight into these skills. A questionnaire was administered to 194 students, who assessed their own academic reading skills. In addition, open-ended questions added to the questionnaire and interviews with 14 students were analyzed, yielding eight domains identified as particular challenges. The results revealed that students assessed their information literacy to be the weakest one. The eight areas of challenge included: shortage of time, information literacy, content knowledge, critical literacy, writers’ language style and generic features of texts, teachers’ high expectations and vague instructions, insufficient statistical literacy and insufficient interaction with peers.
|
2022-12-16T15:19:13.548Z
|
15,810,220 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1242/jeb.015818",
"MAG": "2138121917",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc2760273?pdf=render"
}
|
SUMMARY Light signals can entrain circadian clocks, but they can also mask aspects of the circadian output. We have analyzed the masking effects of a lights-on (LOn) signal on Drosophila eclosion. The LOn response results in 12–21% of the flies that emerge on a given day eclosing within 10 min of the LOn signal. Flies that lack the neuropeptide eclosion hormone (EH), or in which its release is inhibited by the tetanus toxin light chain, lack the response. Optic photoreceptors in both the ocelli and the compound eyes appear to be required for the response. The LOn signal has two effects: (1) it drastically reduces the interval between EH release and eclosion, presumably by suppressing a transient descending inhibition that immediately follows EH release, and (2) it stimulates premature EH release. The LOn signal does not influence the latency of wing spreading, an EH-regulated post-ecdysis behavior.
|
2022-12-20T23:17:07.212Z
|
14,018,346 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1198/106186006X100579",
"MAG": "2091225596",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In recent years, parallel processing has become widely available to researchers. It can be applied in an obvious way in the context of Monte Carlo simulation, but techniques for “parallelizing” Markov chain Monte Carlo (MCMC) algorithms are not so obvious, apart from the natural approach of generating multiple chains in parallel. Although generation of parallel chains is generally the easiest approach, in cases where burn-in is a serious problem, it is often desirable to use parallelization to speed up generation of a single chain. This article briefly discusses some existing methods for parallelization of MCMC algorithms, and proposes a new “pre-fetching” algorithm to parallelize generation of a single chain.
|
2022-12-25T22:03:44.025Z
|
163,311,528 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/084387149801000129",
"MAG": "2328971808",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
their forces as soon as the crisis was over, as did England after every war. More lightheartedly, but with a grain of truth, Jane maintains that it seems to be the "bad Kings" (what would become the "1066 and All That" view) who looked after their navies best. He took notably long views of the potentials of submarines and aircraft, both in their infancy in 1912, as well as noting the importance of ensuring good health among crews, not only by medical measures but also by keeping holds and decks fresh through better ventilation. Nonetheless, he is dated in some matters, such as the traditional critical view of the deficiencies of British ship design and dockyard administration, and he did not notice that some commanders could use tactical flexibility to obtain decisive results. But there is much to be found in his writing. What then can we say of the importance of the book? Jane may have had the idea of continuing the theme of his Russian and Japanese books, although they had been produced under the impetus of war in 1904-1905, and the gap to 1912 seems rather long. But this book came out when the Anglo-German naval competition was at its height, and served to give deeper meaning to what at times was a jingoistic rivalry. The war followed so soon afterwards that it would be difficult to discern if this particular book had any effect. One can say that, written at the climax of the great era of naval development, it does stand as a statement of the position and experience of that era, and shows the confidence, so soon to be shattered, of that generation. Perhaps one could also say that it was the culmination of Jane's work in publicising the Royal Navy and indeed all navies, for throughout that hectic period he must have contributed greatly to the understanding of, and lack of real opposition to, great naval expenditure. The book therefore is important, not only for its views and information, but also for the way in which it represents an era.
|
2022-01-27T03:00:46.953Z
|
142,976,818 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2307/305326",
"MAG": "1605063257",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://www.biodiversitylibrary.org/itempdf/26995"
}
|
Reading is a hobby to open the knowledge windows. Besides, it can provide the inspiration and spirit to face this life. By this way, concomitant with the technology development, many companies serve the e-book or book in soft file. The system of this book of course will be much easier. No worry to forget bringing the soviet men of science academicians and corresponding members of the academy of sciences of the ussr book. You can open the device and get the book by on-line.
|
2022-02-09T07:44:52.401Z
|
211,206,372 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CAC48633.2019.8997385",
"MAG": "3006243566",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Here, a persistent dwell-time(PDT) approach is employed for reliable stabilization of Delta operator(DO) switched systems. For DO switched nonlinear systems, the switching stabilization criterion is proposed by using PDT approach. Based on this stability criterion, the reliable controller and the switching law with PDT are designed to make sure that the closed-loop system is globally uniformly asymptotically stable(GUAS). The performance of the proposed approach is illustrated by the simulation results.
|
2022-01-27T02:00:14.402Z
|
17,123,222 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICASSP.1999.758282",
"MAG": "2150879690",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A new class of FIR filtering algorithms and VLSI architectures based on the multirate approach were recently proposed. They not only reduce the computational complexity in FIR filtering, but also retain attractive implementation-related properties such as regularity and multiply-and-accumulate structure. In addition, the multirate feature can be applied to low-power/high-speed VLSI implementation. These properties make the multirate FIR filtering very attractive in many DSP and communication applications. In this paper, we propose a novel adaptive filter based on this new class of multirate FIR filtering structures. The proposed adaptive filter inherits the advantages of the multirate structures such as low computational complexity and low-power/high-speed applications. Moreover, the multirate feature helps to improve the convergence property of the adaptive filters.
|
2022-03-04T21:56:52.241Z
|
29,927,744 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1089/end.2009.0158",
"MAG": "1989927169",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
INTRODUCTION
Ultrasound imaging, using either an inline or an external transducer, is a standard method for extracorporeal shockwave lithotripsy (SWL) monitoring. This study investigates whether image distortions caused by the low sound speed of fatty tissue could lead to incorrect stone positioning such that disintegration is affected.
MATERIALS AND METHODS
To define the accuracy needed for SWL monitoring, the dependency of fragmentation efficiency on the distance between stone center and SWL focus was examined by in vitro model stone tests. In a clinical study, 15 patients with kidney stones were treated with a Dornier Sigma FarSight. This lithotripter was equipped with both an inline and an external transducer. They were operated alternately to check for inconsistencies, which would indicate ultrasound image distortions. In addition, the ultrasound paths from the transducer to the SWL focus were analyzed for error estimation.
RESULTS AND DISCUSSION
In the model stone tests, the number of shock waves required for complete fragmentation doubled if the stone was about 7.5 to 10 mm off focus in lateral direction. In the clinical trial, the stone positions obtained from an inline and an external transducer coincided within a 5 mm range of tolerance, but that approach suffered from some practical difficulties, resulting in measurement imprecision. The sound path analysis showed that the lengths through fatty tissue were too short to result in significant image distortion. The body mass index (20-31 kg/m(2)) was representative, except for very obese patients. Additional confirmation of correct stone positioning could be achieved quite easily by looking for pixel movement in the B-mode image or employing Doppler hit/miss monitoring.
CONCLUSION
Within the study group, no image distortion caused by fatty tissue that could be clinically relevant for SWL was observed.
|
2022-11-17T16:43:03.882Z
|
210,138,580 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21608/ajnsa.2019.13053.1217",
"MAG": "2995602404",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://ajnsa.journals.ekb.eg/article_65864_8bfbb5c5f74a1db41b87e6a5395b3ae8.pdf"
}
|
This study assessed the clinical usefulness of the 2D-Array Seven29 ,which may compensate for the of the water phantom, by comparing the radiological doses between the two depending on five field sizes. The experimental equipment used was a linear accelerator for medical use, treatment planning system (TPS) , water phantom, 2D-Array, solid phantoms,( Semiflex , Pinpoint) types ion chamber and electrometer. The field size was 10 x 10 cm2 and the radiation energies of the photon beam were 6 MV and 15 MV, The field size involved (1×1, 2×2, 3×3, 4×4, 5×5,) for each energy. The relative deviation ratio of the TPS to both chamber in water phantom and TPS to 2darray in the solid phantom was calculated. The measured doses in standard phantom were less than the TPS values for small field dimensions for fields less than 3×3 cm2, The measured data by 2D-Array data for fields 2×2 and 3×3cm2 this difference within ±2% is due to good accuracy of measurement planning system for field size 1×1cm2. The measured in standard phantom were less than the TPS values for small field dimensions and the measured data by 2D-Array for 6 MV shows mild differences between the TPS and the experimental data. Small difference existed between the TPS and the experimental data using 2D-Array for 15 MV the results were the same for TPS and measured data, at only field dimension of 1×1cm2. Measured data was increased as field area enlarged from 2×2 to 5×5cm2 by constant value of 4%.
|
2022-06-04T07:09:22.022Z
|
219,320,391 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4161/cib.2.1.7503",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://doi.org/10.4161/cib.2.1.7503"
}
|
Wnt/β-catenin canonical pathway is critical for normal embryonic development; mutations and aberrant expression of specific components of this pathway can be oncogenic. Mitogen-activated protein kinase (MAPK) pathways, prominent in intracellular signaling, have been shown to have unique and provocative roles that impact the Wnt/β-catenin signaling. We discuss recent insights that implicate the three major pathways of the MAPK network, i.e., mediated by p38, c-Jun N-terminal (JNK) kinase, and Extra-cellular-Regulated Kinases (ERK) and their downstream signaling elements in Wnt/β-catenin signaling. Novel “crosstalk” among MAPK and Wnt/β-catenin canonical signalling pathways is essential. A fuller understanding of how such signaling is integrated during development is a high-value target for future research.
|
2022-12-09T22:35:41.046Z
|
1,616,211 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1039/B203459J",
"MAG": "1987337574",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The fluorescence of PpIX induced by topical application of 5-aminolevulinic acid (ALA) in normal mouse skin was studied noninvasively by means of a fibre optic probe. The fluorescence excitation spectrum of PpIX exhibits five distinct peaks at around 408. 510, 543, 583 and 633 nm under fluorescence monitoring at the second emission peak of PpIX (705 nm). The transmission of the excitation light is wavelength dependent: the long wavelength light (>600 nm) penetrates deeper into the tissues by a factor of 6 compared with the short wavelength light (<590 nm). Thus, the fluorescence excitation spectrum of PpIX measured on the surface of the skin can be used to estimate the depth of the penetration of topically applied ALA. The fluorescence excitation spectra calculated for the depth 1.1 mm obtained the best fit with the experimentally measured spectra after topical application of ALA.
|
2022-12-19T18:37:21.003Z
|
35,850,293 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4236/EPE.2013.59060",
"MAG": "2045565922",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Any problem with voltage in a power network is undesirable as it aggravates the quality of the power. Power electronic devices such as Voltage Source Converter (VSC) based Static Synchronous Compensator (STATCOM) etc. can be used to mitigate the voltage problems in the distribution system. The voltage problems dealt with in this paper are to show how to mitigate unbalanced voltage sags and voltage unbalance in the CIGRE Low Voltage (LV) test network and networks like this. The voltage unbalances, for the tested cases in the CIGRE LV test network are mainly due to single phase loads and due to unbalanced faults. The compensation of unbalanced voltage sags and voltage unbalance in the CIGRE distribution network is done by using the four STATCOM compensators already existing in the test grid. The simulations are carried out in DIgSILENT power factory software version 15.0.
|
2022-09-10T21:58:13.690Z
|
8,777,004 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4314/AHS.V11I1.65007",
"MAG": "1545067974",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Central nervous system (CNS) involvement, one of the most devastating clinical manifestations of tuberculosis (TB) is noted in 5 to 10% of extrapulmonary TB cases, and accounts for approximately 1% of all TB cases. Definitive diagnosis of tuberculous meningitis (TBM) depends upon the detection of the tubercle bacilli in the CSF. Every patient with TBM should preferably be evaluated by imaging with contrast enhanced CT either before or within the first 48 hours of treatment. An extra-neural focus of tuberculosis should be sought clinically and radiologically in all patients with CNS TB as it may indicate safer and more accessible sites for diagnostic samplings. A minimum of 10 months treatment is warranted, prompted by the uncertain influences of disease severity, CNS drug penetration, undetected drug resistance and patient compliance. All patients with TB meningitis may receive adjunctive corticosteroids at presentation regardless of disease severity even for those with HIV infection. Drug resistance is strongly associated with previous treatment. The key principle of managing drug-resistant TB is never to add a single drug to a failing regimen. Early ventriculo-peritoneal shunting should be considered in those with hydrocephalus failing medical management. The single most important determinant of outcome is the stage of tuberculous meningitis at which treatment has been started.
|
2022-09-13T22:23:54.543Z
|
42,227,231 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3109/10428199409051685",
"MAG": "2095377758",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Combined immunophenotyping and karyotyping was performed in seven cases of peripheral T cell lymphoma with complex aberrant clones. Various lymphocytic cell populations entered mitosis, whereas all aberrant cells belonged to the T helper/inducer cell population. Lymphomas with the same recurrent chromosome aberrations, i.e. inversion inv(14)(q11q32.1) and isochromosome i(8)(q10), had a very similar immunophenotype. The aberrant cells in these cases expressed CD3+, CD4+, CD7+, CD45RO+. The immunophenotypic similarity is underlined in one case of T prolymphocytic leukemia, in whom the aberrant cells lost the CD8 antigen originally present, during cultivation with PHA. In one case of Sézary's syndrome, two or possibly even three different clones as well as nonclonal aberrations were identified within the T (helper/inducer) cell population, providing further evidence that chromosomal instability is a characteristic feature of cutaneous T cell lymphoma.
|
2022-12-10T17:53:10.340Z
|
199,506,347 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1523/JNEUROSCI.0776-19.2019",
"MAG": "2966799408",
"PubMedCentral": "6764203"
},
"license": null,
"status": null,
"url": null
}
|
Despite the prevalent use of alerting sounds in alarms and human–machine interface systems and the long-hypothesized role of the auditory system as the brain's “early warning system,” we have only a rudimentary understanding of what determines auditory salience—the automatic attraction of attention by sound—and which brain mechanisms underlie this process. A major roadblock has been the lack of a robust, objective means of quantifying sound-driven attentional capture. Here we demonstrate that: (1) a reliable salience scale can be obtained from crowd-sourcing (N = 911), (2) acoustic roughness appears to be a driving feature behind this scaling, consistent with previous reports implicating roughness in the perceptual distinctiveness of sounds, and (3) crowd-sourced auditory salience correlates with objective autonomic measures. Specifically, we show that a salience ranking obtained from online raters correlated robustly with the superior colliculus-mediated ocular freezing response, microsaccadic inhibition (MSI), measured in naive, passively listening human participants (of either sex). More salient sounds evoked earlier and larger MSI, consistent with a faster orienting response. These results are consistent with the hypothesis that MSI reflects a general reorienting response that is evoked by potentially behaviorally important events regardless of their modality. SIGNIFICANCE STATEMENT Microsaccades are small, rapid, fixational eye movements that are measurable with sensitive eye-tracking equipment. We reveal a novel, robust link between microsaccade dynamics and the subjective salience of brief sounds (salience rankings obtained from a large number of participants in an online experiment): Within 300 ms of sound onset, the eyes of naive, passively listening participants demonstrate different microsaccade patterns as a function of the sound's crowd-sourced salience. These results position the superior colliculus (hypothesized to underlie microsaccade generation) as an important brain area to investigate in the context of a putative multimodal salience hub. They also demonstrate an objective means for quantifying auditory salience.
|
2022-12-13T06:23:47.655Z
|
30,833,382 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/TEST.1998.743255",
"MAG": "2138551793",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A novel infrared (IR) optical probing technique which provides fast and direct access to diffusion (p-n junction) nodes directly through the silicon substrate is described. The optical probing technology allows waveform measurements to be obtained directly from internal nodes of a CMOS integrated circuit (IC). These measurements can be made on C4 (Flip Chip) mounted ICs in stand-alone, MCM or any other package type for which the chip backside is accessible and the silicon substrate can be thinned. Timing waveforms taken from state of the art Intel microprocessors running at core frequencies >400 MHz using this IR probing technique have been obtained and are presented.
|
2022-12-21T05:55:42.207Z
|
173,994,517 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S0954579419000610",
"MAG": "2948358043",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract Though theory suggests that individual differences in neuroticism (a tendency to experience negative emotions) would be associated with altered functioning of the amygdala (which has been linked with emotionality and emotion dysregulation in childhood, adolescence, and adulthood), results of functional neuroimaging studies have been contradictory and inconclusive. We aimed to clarify the relationship between neuroticism and three hypothesized neural markers derived from functional magnetic resonance imaging during negative emotion face processing: amygdala activation, amygdala habituation, and amygdala-prefrontal connectivity, each of which plays an important role in the experience and regulation of emotions. We used general linear models to examine the relationship between trait neuroticism and the hypothesized neural markers in a large sample of over 500 young adults. Although neuroticism was not significantly associated with magnitude of amygdala activation or amygdala habituation, it was associated with amygdala–ventromedial prefrontal cortex connectivity, which has been implicated in emotion regulation. Results suggest that trait neuroticism may represent a failure in top-down control and regulation of emotional reactions, rather than overactive emotion generation processes, per se. These findings suggest that neuroticism, which has been associated with increased rates of transdiagnostic psychopathology, may represent a failure in the inhibitory neurocircuitry associated with emotion regulation.
|
2022-12-31T18:27:57.468Z
|
64,471,678 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4018/978-1-61350-056-9.CH011",
"MAG": "2480897209",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Traffic congestion problem is rising day-by-day due to increasing number of small to heavy weight vehicles on the road, poorly designed infrastructure, and ineffective control systems. This chapter addresses the problem of estimating computer vision based traffic density using video stream mining. We present an efficient approach for traffic density estimation using texture analysis along with Support Vector Machine (SVM) classifier, and describe analyzing traffic density for on-road traffic congestion control with better flow management. This approach facilitates integrated environment for users to derive traffic status by mining the available video streams from multiple cameras. It also facilitates processing video frames received from video cameras installed in traffic posts and classifies the frames according to traffic content at any particular instance. Time series information available from various input streams is combined with traffic video classification results to discover traffic trends. DOI: 10.4018/978-1-61350-056-9.ch011
|
2022-06-14T22:47:07.590Z
|
135,384,497 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5281/ZENODO.1002339",
"MAG": "2762313416",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Background: The AquaPonic system is an eco-friendly recycling method that can save energy and reduce the impact of environmental pollution from fish manure by utilizing it as a nutrient for plant growth. The aquaponic system is required to measure and control the suitability and efficiency of the circulation system depending on the concentration of the ammonium ion and the nitrate ion. For the measurement of nitrate and ammonium ions, ISE (Ion Selective Electrodes) were fabricated and applied to the designed system.
Methods: ISE were prepared for the measurement and analysis of ammonium and nitrate ions, which are the most important components of nitrogen circulation in the fish excrement of the designed aquaponic-system. The temperature, humidity, light composition and light intensity of plant growing area were controlled to collect meaningful information about growth of the plant. Lettuce was cultivated in a total of 60 ports and cultivated in a hydroponic cultivation method using fish excrement as a nutrient. Nitrate and ammonium ions were measured at 24 hour intervals for 1 month of growth of tilapia and lettuce. In order to investigate the growth of lettuce, weights and length were collected and the images of tilapia were obtained at feeding to determine the growth of tilapia.
Results: The analysis of the weight, length, and nutrients of the lettuce grown in the designed aqua phonics system showed that the designed aquaponic-system is an efficient system.
Discussions: In order to design an aquaponic-system for various crops and species, it is considered necessary to conduct experiments on aquaponic-system which combines various crops and species. Further research on the algorithm that can control the system in optimum environment is needed by collecting information about growth of plant and fish in controlled environment.
Conclusion: It is expected that further research on the development of algorithms that can determine the optimum growth environment by acquiring the growth information as changing the growth environment through the controllable system.
|
2022-07-13T19:00:37.956Z
|
82,660,685 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2166/WST.1993.0369",
"MAG": "631918062",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Development of the need for personal water treatment devices has evolved from consumer interest in improving and ensuring the quality of drinking water. The need also extends to the quality of untreated or partially treated waters such as that used by hikers, campers, recreational home and boat owners, and families or communities having individual home and small system water sources. It is essential that such devices be capable of removing all types of pathogenic microorganisms likely to be found in contaminated water. For this reason the U.S. Environmental Protection Agency has suggested such units be capable of removing Klebsiella terriaena. Giardia cysts and enteric viruses. Three identical water purifiers were evaluated for the inactivation of rotavirus SA-11, hepatitis A virus, poliovirus type 1, the bacterial virus MS-2, Klebsiella terriaena and Giardia muris cysts. The units depend upon a thermal cycler combined with activated carbon for removal of the test organisms. The units were challenged with the organisms suspended in tapwater after 4, 76 and 240 cycles of operation. The units were also tested with a “worst case” water quality of 1500 mg/l dissolved solids, 10 mg/l organic matter and with a water turbidity of 30 NTU. In all cases, complete inactivation of the viruses, bacteria and cysts occurred after operation of the 35-minute cycle. This resulted in a greater than 3-log (99.9%) inactivation of cysts, a greater than 6 log (99.9999%) inactivation of K. terriaena and 4-log (99.99%) inactivation of viruses. In conclusion, these units would comply with CTiteria guidelines suggested by the U.S. Environmental Protection Agency for the operation of microbial water purifiers.
|
2022-07-19T19:56:04.858Z
|
102,133,245 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/MA0007740",
"MAG": "2321405485",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The correlation between relative reactivity of the two styrene enantiofaces and geometry of ansa-zirconocene systems has been determined by 13C NMR microstructural analysis of the poly(propylene-co...
|
2022-09-24T16:09:04.543Z
|
252,228,860 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.53516/ajfr.1141172",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Wood and wood-based materials are widely used in the construction industry in the world. The sustainable and renewable nature of wood is seen as an important advantage in contrast to non-renewable resources such as aluminum, steel, concrete, and plastic. In order to protect the advantages of wood and eliminate / reduce its disadvantages, plywood, particle board, fiber board, LVL, CLT, wood plastic composites etc. such as new wood-based engineering products are produced. Plywoods are widely used in automotive, construction, furniture, and many industries. In our country, plywoods are produced using tropical species as well as native tree species. In this study, density, water absorption, thickness swelling, bending resistance, elasticity of modulus in bending and shear strength values of plywood made of beech, okoume and ozigo wood species are investigated. Comparison of plywood produced from tropical species with beech has been made. It has been determined that beech plywood has higher density than okoume and ozigo plywood. It has been determined that beech plywood has higher density than okoume and ozigo plywood. It has been observed that there is a linear relationship between the bending strength, elasticity modulus and shear strength values of beech plywood and their full dry density.
|
2022-09-15T17:36:10.726Z
|
73,883,792 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/026921638900300106",
"MAG": "2167448205",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Nutritional problems in far-advanced disease have complex and interrelated causes. This is particularly true with cancer patients, who may have systemic disease producing multiple physical and psychological effects and who require complex treatment. Some solutions can be found which, if tailored to the individual patient, can improve the quality of life for both relatives and patients.
|
2022-12-11T11:29:45.609Z
|
84,742,675 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1096-3642.1984.TB00534.X",
"MAG": "2017453674",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Living sharks, skates and rays share several derived skeletal characters that are absent in most extinct elasmobranchs, suggesting a monophyletic group of ‘higher’ elasmobranchs. Within this group opinions vary as to phylogenetic relationships, although three broad groups are generally recognized. Arguments for and against monophyly of these group (batoids; squalomorphs; galeomorphs) are examined. Many of their contained taxa are also of questionable validity. Cladistic analysis of living galeomorphs reveals a sequence of characters supporting monophyly of the group as whole, but not of its more generalized contained taxa. The temporal distribution of fossil galeomorphs corroborates the hypothesis of relationship suggested by neontological data; i.e. there is considerable stratigraphic harmony with Recent phylogenetic data.
|
2022-12-12T13:32:02.621Z
|
208,730,136 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/15421406.2019.1648049",
"MAG": "2982120132",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract We have designed and synthesized blue emitting compounds, DBF-PI and DBT-PI, by incorporating pyrene and imidazole groups as main chromophore and introducing dibenzofuran and dibenzothiophene groups. Pyrene and diphenyl-imidazole were used to synthesize blue emitters of 1-(4-Dibenzofuran-4-yl-phenyl)-4,5-diphenyl-2-pyren-1-yl-1H-imidazole (DBF-PI) and 1-(4-Dibenzothiophen-4-yl-phenyl)-4,5-diphenyl-2-pyren-1-yl-1H-imidazole (DBT-PI). The optical and electroluminescence properties of newly synthesized materials were measured. Both materials emit blue photoluminescence in the film state and DBF-PI have a high PLQY value of about 80% in solution state. The synthesized materials were applied as EML in non-doped devices, and high efficiency of 2.92 cd/A and EQE of 2.07% in DBF-PI device were achieved.
|
2022-12-16T02:46:15.481Z
|
117,948,567 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1103/PHYSREVB.72.104111",
"MAG": "1636823310",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Detailed studies of the properties of ceramic ${\mathrm{CaCu}}_{3}{\mathrm{Ti}}_{4}{\mathrm{O}}_{12}$ (CCTO) have clarified the physics of this interesting material and revealed several features not reported before. The dielectric relaxational properties of CCTO are explained in terms of a capacitive-layer model, as for an inhomogeneous semiconductor, consisting of semiconducting grains and insulating grain boundaries as also concluded by others. The kinetics of the main [low-temperature $(T)$] relaxation reveal that two different thermally activated processes in CCTO grains control the dynamics. A likely candidate defect responsible for the two processes is the oxygen vacancy which is a double donor. A higher-$T$ relaxation is determined by grain boundary conduction. Both Nb and Fe doping lowered both the apparent dielectric constant ${\ensuremath{\epsilon}}^{\ensuremath{'}}$ and the dielectric loss, but increased Fe doping led to more dramatic effects. At 3 at. % Fe doping, the anomalous ${\ensuremath{\epsilon}}^{\ensuremath{'}}(T)$ response was removed, making the CCTO an intrinsic, very-low-loss dielectric. The intrinsic ${\ensuremath{\epsilon}}^{\ensuremath{'}}(\ensuremath{\simeq}75)$ and its $T$ dependence are measured and shown to be largely determined by a low-lying soft TO phonon. At low $T$, cubic CCTO transforms into an antiferromagnetic phase at ${T}_{N}=25\phantom{\rule{0.3em}{0ex}}\mathrm{K}$. ${T}_{N}$ is essentially independent of Nb doping (up to 4 at. %) and of hydrostatic pressure (up to $\ensuremath{\sim}7\phantom{\rule{0.3em}{0ex}}\mathrm{kbar}$), but decreases significantly with Fe doping. Analysis of the high-$T$ dependence of the magnetic susceptibility provided insight into the role of Fe as a dopant. Finally, an ${\ensuremath{\epsilon}}^{\ensuremath{'}}(\mathrm{T})$ anomaly associated with the onset of antiferromagnetic order has been discovered, providing evidence for coupling between the polarization and sublattice magnetization. The possible origin of this coupling is discussed.
|
2022-12-16T05:58:55.744Z
|
251,691,364 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/rel13080751",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2077-1444/13/8/751/pdf?version=1660732365"
}
|
Between June and August 1947, Qian Xuexi and William Empson exchanged 12 letters on the issue of Arthur Waley’s misinterpretation of the Daodejing. Through a thorough analysis of these new-found letters and Qian’s English translation of the Daodejing, I intended to show that the central arguments between Qian and Empson are around two major problems concerning Waley’s translation: Waley’s ideas of the Daodejing being part of the “Yoga-Quietism” tradition that Waley himself tried to invent, and Waley’s idea of opposing Daoism to Legalism. Qian firmly rejected that the ideas in the Daodejing were the same as some Western ideas. Neither did he accept that the ideas of the Daodejing were under the influence of either Western culture or Indian religious philosophy. Instead, Qian explained that the so-called “Yoga-Quietism” did not derive from China. Therefore, in his view, Waley’s approach was fundamentally problematic. Qian’s view eventually convinced Empson, who initially opposed Qian’s stance. Qian and Empson’s letters and Qian’s English translation of the Daodejing, though never published, indicate the value of Qian’s ideas and the meaning of their intellectual interaction.
|
2022-12-21T17:32:54.005Z
|
53,103,408 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1037/xge0000503",
"MAG": "2898127059",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://iris.unitn.it/bitstream/11572/221725/6/Turatto_2018_desensitizing%20%283%29.pdf"
}
|
For the good and the bad, the world around us is full of distraction. In particular, onset stimuli that appear abruptly in the scene grab attention, thus disrupting the ongoing task. Different cognitive mechanisms for distractor filtering have been proposed, but prevalent accounts share the idea that filtering is accomplished to shield target processing from interference. Here we provide novel evidence that challenges this view, as passive exposure to a repeating visual onset is sufficient to trigger learning-dependent mechanisms to filter the unwanted stimulation. In other words, our study shows that during passive exposure the cognitive system is capable of learning about the characteristics of the salient yet irrelevant stimulation, and to reduce the responsiveness of the attention system to it, thus significantly decreasing the impact of the distractor upon start of an active task. However, despite passive viewing efficiently attenuates the spatial capture of attention, a short-lived performance cost is found when the distractor is initially encountered within the context of the active task. This cost, which dissipates in a few trials, likely reflects the need to familiarize with the distractor, already seen during passive viewing, in the new context of the active task. Although top-down inhibitory signals can be applied to distractors for the successful completion of goal-directed behavior, our results emphasize the role of more automatic habituation mechanisms for distraction exclusion based on a neural model of the history of the irrelevant stimulation.
|
2022-12-30T01:09:35.042Z
|
135,569,321 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4028/www.scientific.net/AMR.194-196.2031",
"MAG": "1977447863",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Rock creep is a hot topic and key point in engineering geology. Based on renormalization group theory, the rock creep instability of micro-mechanism can be described as follow: with the expanding and interaction of micro-cracks and the main fault forms, which leads to failure. Comparing with the similarity of rock creep and rock compression process, and combining results of rock creep process, it is shown that there a distinct pertinence between different stages of rock creep. The relationship characteristics of different evolutionary stages can be used to provide scientific foundation for rock creep.
|
2022-01-27T18:40:13.375Z
|
108,200,543 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2737/PNW-RN-450",
"MAG": "1837204167",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A pilot study was undertaken to determine drying rates for small-diameter, unsplit paper birch firewood that was dried: (1) in a conventional top-covered pile; (2) in a simple, temporary solar kiln; and (3) in tree length. Drying rates were the same for firewood piles whether they were in the temporary kiln or only covered on top to keep rain or snow from entering the pile. Trees that were severed at the stump and left to dry in tree length form, complete with branches and leaves, however, dried slower than firewood cut to length, stacked and top-covered or placed in the temporary solar kiln.
|
2022-02-10T07:21:31.155Z
|
96,913,707 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1081/AL-120016549",
"MAG": "2060343008",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
ABSTRACT The spectrophotometric N,N′-diethyl-p-phenylenediamine (DPD) method for the determination of free chlorine in saline matrices used as dialysis fluids (DF) in hemodialysis treatment was investigated by multiple wavelength detection (multivariate DPD-method). This method was compared with the current standard DPD-method (univariate DPD-method) that uses single wavelength detection (515 nm). The multivariate DPD-method showed the best performance because the influence of the high ionic strengths of the saline matrices on the equilibrium among the DPD species was well modeled only by the multivariate approach. The univariate DPD-method showed biased results towards low chlorine concentrations (ca. 25%) in DF samples. Through the developed methodology it was possible to quantify free chlorine directly in dialysis fluids. The multivariate method showed to be adequate as a last quality control before a hemodialysis session. The regression by partial least squares (PLS) using two principal components and full cross-validation was applied to the absorbance values in the interval 200–600 nm. The root mean square errors of prediction (RMSEP) was 0.08 mg L−1. Free chlorine concentrations ranging from 0.2 to 0.7 mg L−1 were assayed in DF samples.
|
2022-08-12T07:26:20.752Z
|
49,332,814 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.12809/hkmj176902",
"MAG": "2809102540",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://www.hkmj.org/system/files/hkmj176902.pdf"
}
|
With Hong Kong's ageing population, advancement of medical technologies and hospital congestion, it is not uncommon for emergency physicians to encounter complicated critically ill patients in daily practice. It becomes a fundamental role of emergency physicians to initiate timely diagnostic and therapeutic interventions to save a patient's life and improve their prognosis. It is the reason a critical care service has been developed in emergency departments worldwide over the last decade. This article shares how emergency department intensivists can contribute to this novel model of care with some illustrative cases. Advanced airway and peri-intubation management, difficult mechanical ventilation, treatment of shock, circulatory arrest, and metabolic disturbances can be safely and efficiently handled in the current emergency department setting. Obstacles, barriers, and the road ahead will be discussed.
|
2022-09-02T04:48:24.439Z
|
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