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255M
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236,934,872 |
{
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"DOI": "10.1021/jacs.1c05890",
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|
The asymmetric functionalization of C-H is one of the most attractive strategies in asymmetric synthesis. In the past decades, catalytic enantioselective C(sp3)-H functionalization has been intensively studied and successfully applied in various asymmetric bond formations, whereas asymmetric C(sp3)-H alkylation was not well developed. Photoredox catalysis has recently emerged as an efficient way to synthesize organic compounds under mild conditions. Despite many photoinduced stereoselective reactions that have been achieved, the related enantioselective C(sp3)-C(sp3) coupling is challenging, especially of the photocatalytic asymmetric C(sp3)-H radical alkylation. Here, we report a visible light induced Cu catalyzed asymmetric sp3 C-H alkylation, which is effective for coupling with unbiased primary, secondary, and tertiary alkyl fragments in high enantioselectivities. This reaction would provide a new approach for the synthesis of important molecules such as unnatural α-amino acids and late-stage functionalization of bioactive compounds, and will be useful for modern peptide synthesis and drug discovery.
|
2022-12-15T18:12:36.776Z
|
207,179,284 |
{
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"ArXiv": null,
"DOI": "10.1021/jacs.7b04422",
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"status": null,
"url": null
}
|
In future nanocircuits based on two-dimensional (2D) materials, the ideal nonvolatile memories (NVMs) would be based on 2D multiferroic materials that can combine both efficient ferroelectric writing and ferromagnetic reading, which remain hitherto unreported. Here we show first-principles evidence that a halogen-intercalated phosphorene bilayer can be multiferroic with most long-sought advantages: its "mobile" magnetism can be controlled by ferroelectric switching upon application of an external electric field, exhibiting either an "on" state with spin-selective and highly p-doped channels, or an "off" state, insulating against both spin and electron transport, which renders efficient electrical writing and magnetic reading. Vertical polarization can be maintained against a depolarizing field, rendering high-density data storage possible. Moreover, all those functions in the halogenated regions can be directly integrated into a 2D phosphorene wafer, similar to n/p channels formed by doping in a silicon wafer. Such formation of multiferroics with vertical polarization robust against a depolarizing field can be attributed to the unique properties of covalently bonded ferroelectrics, distinct from ionic-bonded ferroelectrics, which may be extended to other van der Waals bilayers for the design of NVM in future 2D wafers. Every intercalated adatom can be used to store one bit of data: "0" when binding to the upper layer and "1" when binding to the down layer, giving rise to a possible approach of realizing single atom memory for high-density data storage.
|
2022-12-18T12:05:22.967Z
|
43,061,365 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1006/inco.1993.1024",
"MAG": "1981808971",
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},
"license": "elsevier-specific: oa user license",
"status": "BRONZE",
"url": "https://doi.org/10.1006/inco.1993.1024"
}
|
Model-checking is a method of verifying concurrent systems in which a state-transition graph model of the system behavior is compared with a temporal logic formula. This paper extends model-checking for the branching-time logic CTL to the analysis of real-time systems, whose correctness depends on the magnitudes of the timing delays. For specifications, we extend the syntax of CTL to allow quantitative temporal operators such as ?? <5, meaning "possibly within 5 time units." The formulas of the resulting logic, Timed CTL (TCTL), are interpreted over continuous computation trees, trees in which paths are maps from the set of nonnegative reals to system states. To model finite-state systems we introduce timed graphs-state-transition graphs annotated with timing constraints. As our main result, we develop an algorithm for model-checking, for determining the truth of a TCTL-formula with respect to a timed graph. We argue that choosing a dense domain instead of a discrete domain to model time does not significantly blow up the complexity of the model-checking problem. On the negative side, we show that the denseness of the underlying time domain makes the validity problem for TCTL ?11-hard. The question of deciding whether there exists a timed graph satisfying a TCTL-formula is also undecidable.
|
2022-12-22T15:08:52.112Z
|
201,874,113 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3917/RE1.087.0083",
"MAG": "2969309326",
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|
A l’issue de pres de dix ans de travaux de recherche preparatoires finances par les programmes de la Commission europeenne, les services europeens Copernicus de surveillance de l’atmosphere sont entres dans une phase operationnelle a la fin de l’annee 2015 (https://atmosphere.copernicus.eu/). Ils proposent a tout utilisateur des previsions, cartographies et autres donnees valorisees relatives a la composition chimique de l’atmosphere a l’echelle globale, a l’ozone stratospherique, au rayonnement ultraviolet (UV) et a la qualite de l’air en Europe. La Commission europeenne a delegue, en novembre 2014, au Centre europeen de Prevision ECMWF1 le pilotage et la gestion de ces services operationnels regroupes sous la banniere des CAMS (Copernicus Atmosphere Monitoring Services). Ceux-ci resultent d’importants travaux de recherche menes par pres d’une cinquantaine d’equipes europeennes exploitant tous types d’outils (modeles numeriques) ou de donnees (in situ et satellite) pour elaborer des diagnostics et des previsions a differentes echelles d’espace et de temps. Une nouvelle ere est ainsi ouverte avec la mise a disposition libre et gratuite de produits inedits par leur qualite et leur exhaustivite, focalises sur les besoins des utilisateurs et ciblant des sujets aussi sensibles que l’environnement atmospherique.
|
2022-02-08T05:02:15.691Z
|
52,918,348 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICASSDA.2018.8477603",
"MAG": "2895891283",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Automatic frog sound identification system is one of the useful approaches to assist experts in identifying frog species and to replace manual techniques claimed to be costly and time consuming. However, to execute an automatic system in noisy environment due to background noises is a challenging task. Instead of depending on physical observation procedure to identify the particular species, this study proposes an automated frog identification system based on bioacoustics signal analysis. Experimental studies of 15 species of frogs are used in this study. These calls are then corrupted by 20dB 10dB and 5dB in different stationary and nonstationary noises. The calls are segmented with three different techniques which are Sinusoidal Modeling (SM), combination of Short Time Energy (STE) and Short Time Average Zero Crossing Rate (STAZCR) (STE+STAZCR) and combination of Energy (E) and Zero Crossing Rate (ZCR) (E+ZCR). A syllable feature extraction method i.e. mel-frequency cepstrum coefficients (MFCC) employed to extract the segmented signal. Subsequently, k nearest neighbor (kNN) are employed in order to evaluate the performance of the identification system. Two experiments have been experimented to compare the performace of SM, E+ZCR and STE+ZTAZCR. The classification performance for three techniques are found to be 90.330/0, 93.340/0 and 93.21% for the SM, E+ZCR and STE+ZTAZCR, respectively.
|
2022-02-11T22:05:58.088Z
|
248,995,097 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/CBO9781316151907.044",
"MAG": null,
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"license": null,
"status": null,
"url": null
}
|
228Sovereign immunity — Agencies and instrumentalities of foreign States — Whether contracts between United States impressario and USSR State concert society were commercial or artistic and governmental in character — Foreign Sovereign Immunities Act 1976 — Whether Section 1605 (a) (5) (B) of the Act restricted scope of “commercial activity” exception to sovereign immunity — The law of the United States
|
2022-05-24T19:24:23.542Z
|
95,173,467 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/00908318608946045",
"MAG": "2009809286",
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"license": null,
"status": null,
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}
|
Fundamental principles of the X-ray diffraction of mesomorphic materials are discussed at length, especially for petroleum asphaltenes. Stepwise procedures for handling X-ray diffraction laboratory data are presented.
|
2022-06-27T18:42:05.990Z
|
60,446,253 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/9780470686652.EAE055",
"MAG": "1481406490",
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"license": null,
"status": null,
"url": null
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|
This article presents the current trends in modeling and simulation of transitional and turbulent flows using the state-of-the-art of large eddy simulation (LES) computational strategies. The fundamentals of both the explicit and implicit LES strategies are presented followed by indicative examples showing the applicability of these approaches. Issues relating to numerical uncertainties and validation are also discussed.
Keywords:
turbulence;
turbulence simulation;
large-eddy simulation;
implicit large-eddy simulation;
aerodynamics;
uncertainty quantification;
computational fluid dynamics;
numerical methods
|
2022-09-12T12:44:35.991Z
|
144,117,256 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/089692059201900304",
"MAG": "2021294540",
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},
"license": null,
"status": null,
"url": null
}
|
In recent years a perspective known as Analytical Marxism has come to the forefront of Marxist thought. This perspective considers Marxism to be a useful tradition, but one that is haunted by a number of theoretical and methodological flaws. This new perspective claims to have corrected these "flaws" through its methodology, particularly the usage of methodological individualism, rational choice models, and game theory, as well as a new analysis of exploitation and class formation. The purpose of this paper is to survey and evaluate the works of Analytical Marxists and their critics in these areas.
|
2022-09-13T20:10:17.019Z
|
117,880,672 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21236/ada042751",
"MAG": "1670995219",
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},
"license": null,
"status": "CLOSED",
"url": null
}
|
Abstract : In this report, certain applications of the Cramer-Rao bound to problems in radar echo time-of-arrival estimation are presented. These applications encompass point target echos, two-point target echos, and distributed target echos. With respect to point targets and two-point targets, a modified Cramer-Rao bound is derived and the results are substantially tighter than those of the conventional Cramer-Rao bound. In applying the Cramer-Rao bound to distributed targets, a sampled-data formulation is presented and a numerical example corresponding to a wake parameter estimation problem is given to illustrate the results. (Author)
|
2022-06-02T00:15:02.613Z
|
247,563,470 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/03611981221082572",
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"license": null,
"status": null,
"url": null
}
|
Vehicle electrification delivers fast decarbonization benefits by significantly improving vehicle efficiency and relying on less carbon-intense feedstocks. As power grids transition away from carbon-intensive generation and battery energy density improves, the transportation sector’s greenhouse gas savings may deliver upwards of a 75% reduction in current carbon footprint for many nations. Actual savings depend on many variables, like power grid feedstocks, charging rates and schedules, driver behavior, and weather. A special synergy between power and transportation sectors comes via managed charging and second-life battery uses for energy storage systems. This paper reviews the added carbon and energy savings that can come from these two strategies. If charging stations are widely available at one’s destination, utility-controlled managed charging could reduce emissions from electric vehicle charging by one-third. Downcycling electric vehicle batteries for energy storage can also lower peaker power plant use, avoid curtailment of renewable feedstocks, and lessen households’ power-based carbon footprints by half—or contribute up to 5% of grid power capacity.
|
2022-10-27T20:16:54.101Z
|
24,780,480 |
{
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"DOI": "10.1177/0148607107031003212",
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|
BACKGROUND
Traditionally, percutaneous endoscopic gastrostomy (PEG) placement in the obese patient has been considered a relative contraindication due to the impedance of gastric transillumination and inability to approximate the abdominal and gastric wall. The aim of this study was to determine the overall success rate, morbidity, and PEG-related mortality in overweight and obese patients.
METHODS
Three hundred fifty-five consecutive patients were retrospectively evaluated over a 1-year period at the Virginia Commonwealth University Medical Center for postprocedure-related PEG and PEG/jejunostomy (J) complications. One hundred thirty-four patients were considered overweight (body mass index [BMI] > or = 27 kg/m(2)). Of those, 80 patients were found to be obese (BMI > or = 30 kg/m(2)) with a BMI ranging 30-63 kg/m(2).
RESULTS
Gastrostomy placement was successful in 130 of 134 (97%) overweight patients (p < .05). The overall procedure-related mortality was 0%. The rate of significant complications in overweight and obese patients remained 0% when compared with those patients with a normal BMI. Out of 355 patients, 14 failed to receive a PEG; 3 of these were obese and 1 was overweight. These 4 procedures were aborted due to a paucity of anatomical landmarks and failure to transilluminate the abdominal wall.
CONCLUSIONS
We believe that PEG placement in the overweight and obese patient can be a technically safe procedure according to our success rate of 100%, with a procedure-related mortality rate of 0%. In those overweight and obese patients who require specialized long-term enteral nutrition support, PEG placement should be considered earlier and more frequently.
|
2022-11-19T06:01:58Z
|
81,966,516 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1200/JCO.2018.36.15_SUPPL.5027",
"MAG": "2891002453",
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"license": null,
"status": null,
"url": null
}
|
5027Background: Sip-T, an autologous cellular immunotherapy approved in the US for pts with asymptomatic/minimally symptomatic mCRPC, is produced by culturing peripheral blood mononuclear cells wit...
|
2022-12-18T21:17:16.681Z
|
191,389,240 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2307/504300",
"MAG": "2318773285",
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"status": null,
"url": null
}
|
fig. 8. Details of the soldering and related scientific studies will be reported elsewhere. Carroll is inclined to attribute the full development of granulation by sintering to Greek, Phoenician and Etruscan jewelers of the 7th century B.C., when the smallest grains are known (from about 19 per cm. to about 57 per cm.), whereas she assigns the copper-salt technique'7 to coarser granulation (about 12 per cm.). We have, however, been able to demonstrate that copper-salt granulation occurs in Etruria in the 7th century. This information should thus be a contribution to the debated issue of the origins of Etruscan
|
2022-12-21T15:50:02.527Z
|
208,014,546 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3389/fimmu.2019.02663",
"MAG": "2987628214",
"PubMedCentral": "6889906"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.frontiersin.org/articles/10.3389/fimmu.2019.02663/pdf"
}
|
The immunosuppressive potential of mesenchymal stem cells has been extensively investigated in many studies in vivo and in vitro. In recent years, a variety preclinical and clinical studies have demonstrated that mesenchymal stem cells ameliorate immune-mediated disorders, including autoimmune diseases. However, to date mesenchymal stem cells have not become a widely used therapeutic agent due to safety challenges, high cost and difficulties in providing long term production. A key mechanism underpinning the immunomodulatory effect of MSCs is the production of paracrine factors including growth factors, cytokines, chemokines, and extracellular vesicles (EVs). MSCs derived EVs have become an attractive therapeutic agent for immunomodulation and treatment of immune-mediated disorders. In addition to many preclinical studies of MSCs derived EVs, their beneficial effects have been observed in patients with both acute graft-vs.-host disease and chronic kidney disease. In this review, we discuss the current findings in the field of MSCs derived EVs-based therapies in immune-mediated disorders and approaches to scale EV production for clinical use.
|
2022-12-21T19:42:43.712Z
|
232,371,729 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/SAMI50585.2021.9378613",
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},
"license": null,
"status": null,
"url": null
}
|
This paper presents the application of edit distance functions for the measuring of morphological ambiguity and similarity between the natural languages. We propose sequence and tree edit distance functions for the Universal dependencies framework, which compare both morphological and syntactical annotations of the words in the sentences. The experiments were performed with the Slovak as a reference language and set of Slavic languages for comparison.
|
2022-01-27T17:55:34.104Z
|
196,565,984 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.32412/PJOHNS.V34I1.971",
"MAG": "2951530607",
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"license": null,
"status": null,
"url": null
}
|
Objective: To present a function-preserving surgical technique of post-laryngotracheal resection reconstruction of the subglottic airway using autologous tracheal cartilage composite graft.
Methods:
Design: Case Report
Setting: Tertiary Government Training Hospital
Participants: One
Results: A 77-year-old woman diagnosed with papillary thyroid carcinoma with laryngotracheal invasion underwent total thyroidectomy with laryngotracheal resection. The tracheal defect was reconstructed using end-to-end anastomosis of the trachea to the remaining cricoid. The cricoid (subglottic) defect was repaired using the harvested tracheal cartilage with mucosa. Post-operatively, the patient was maintained on nasogastric tube feeding and tracheostomy tube for 2 weeks. Subsequently, the nasogastric tube and tracheostomy tube were removed and the patient tolerated oral feeding without any airway problem. The last follow-up of the patient was 6 months post-operatively without complications.
Conclusion: Autologous tracheal cartilage may be a potentially promising composite graft for reconstruction of the cricoid (subglottic) defect in a patient following laryngotracheal resection for invasive papillary thyroid carcinoma of the larynx and trachea.
Keywords: tracheal composite graft; laryngotracheal resection; crico-tracheal anastomosis; papillary thyroid carcinoma; subglottic defect
|
2022-02-08T07:02:06.048Z
|
86,398,946 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1182/BLOOD-2018-99-112689",
"MAG": "2911837214",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Introduction : Follicular lymphoma (FL) is a clinically and genetically heterogeneous disease with highly variable patient outcomes. Recently, Huet et al. proposed a 23-gene expression-based risk score for predicting progression-free survival (PFS) in FL patients treated with rituximab and chemotherapy (Huet et al. Lancet Oncology 2018). The m7-FLIPI risk score has also been described as a clinico-genetic model predicting patient outcomes (Pastore et al. Lancet Oncology 2015). Moreover, EZH2 wild-type status and high expression of the FOXP1 transcription factor are associated with increased risk of lymphoma progression (Mottok et al. Blood 2018). This multitude of prognostic tools in FL raises the question whether they identify common biology. The aims of this study were to assess whether the 23-gene predictor score identifies a poor risk group of patients in our own gene expression dataset, and whether commonality exists between the 23-gene score, the m7-FLIPI, EZH2 mutation status and FOXP1 expression.
Methods: In our previous work, we generated Illumina DASL microarray expression profiles for 137 FL patients who were treated with rituximab and CVP chemotherapy (cyclophosphamide, vincristine and prednisone). Using genes from the 23-gene linear risk predictor, we determined each patient's risk score by setting coefficients at -1 and +1 for genes associated with favorable and unfavorable PFS, respectively. We dichotomized the distribution of scores using the maximally selected log-rank statistic. We also performed unsupervised, hierarchical clustering to identify underlying subgroups in an unbiased fashion. Survival analyses were performed using the log-rank test and Cox regression analyses. We used gene set enrichment analysis to identify concordant differences of relevant gene signatures between specimens with either low or high expression of FOXP1.
Results : Twenty genes from the 23-gene predictor (87%) were identified in the DASL gene expression dataset. The coefficients from univariate Cox regression analysis from our data were correlated with coefficients from Huet et al. (Pearson r = .7, P < .001; Spearman r = .44, P = .051). All poor-risk genes from the 23-gene predictor were associated with poor PFS in our data, and vice versa. Concordantly, calculated risk scores were significantly associated with PFS in the univariate Cox regression analysis (P = .007). Dichotomizing the distribution of risk scores identified 68% of cases with high risk score who had inferior PFS and OS compared to 32% of cases with low risk score (5-year PFS 54% vs. 77%, P = .004; 5-year OS 73% vs. 86%, P = .04). Hence, the risk score stratified patients into groups with diverging outcomes. This association was found to be independent of the Follicular Lymphoma Prognostic Index (FLIPI). In addition, the mean risk score was significantly higher in cases with high expression of FOXP1 (P < .001) and in cases with high m7-FLIPI risk score (P = .023). Unsupervised hierarchical clustering identified two main clusters ("cluster 1" and "cluster 2") that were characterized by low and high expression of genes associated with poor outcome, respectively. Patients from "cluster 2" experienced worse PFS compared to patients in "cluster 1" (P = .046; 5-year PFS 54% vs. 68%). The 5-year OS was 72% for patients in "cluster 2", vs. 81% in "cluster 1" (P = .13).
We have previously reported that a germinal centre dark zone signature is enriched in cases with high FOXP1 expression, and the ICA13 signature reported by Huet et al. has been described as being highly expressed in centroblasts. Using gene set enrichment analysis, we found that genes with positive weight and coefficients in the ICA13 and the 23-gene predictor score, respectively, were enriched in the FOXP1-high phenotype (adjusted P = .009 and .005, respectively). GeneMANIA illustrated co-expression interconnectivity among ORAI2, TCF4, AFF3, FOXO1, CXCR4 and FOXP1, suggesting that genes with prognostic significance operate in tightly regulated networks.
Conclusions: Our results exemplify the robustness of the predictor model by Huet et al. Further, we demonstrate biomarker convergence on a common phenotype: FOXP1 expression, EZH2 wild-type status and expression of dark zone-related genes, which characterize a subset of FL cases with adverse outcome following rituximab and chemotherapy.
Sarkozy: Roche/Genentech: Consultancy. Sehn:Roche/Genentech: Consultancy, Honoraria; Amgen: Consultancy, Honoraria; Karyopharm: Consultancy, Honoraria; Lundbeck: Consultancy, Honoraria; Seattle Genetics: Consultancy, Honoraria; Janssen: Consultancy, Honoraria; Abbvie: Consultancy, Honoraria; Celgene: Consultancy, Honoraria; TG Therapeutics: Consultancy, Honoraria; Merck: Consultancy, Honoraria; Morphosys: Consultancy, Honoraria. Weigert:Novartis: Research Funding; Roche: Research Funding. Steidl:Juno Therapeutics: Consultancy; Tioma: Research Funding; Bristol-Myers Squibb: Research Funding; Roche: Consultancy; Seattle Genetics: Consultancy; Nanostring: Patents & Royalties: patent holding.
|
2022-02-10T22:29:05.497Z
|
13,982,056 |
{
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"DOI": "10.1109/WISM.2009.65",
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}
|
The study on XML keyword search gradually becomes the focus of information retrieval. Most previous XML keyword search algorithms are based on SLCA (Smallest Lowest Common Ancestor), but in the process of keyword search, we discover that some weakness or flaw exists in SLCA, it is summarized as follows: (1) the query result is absolutely accurate but it is meaningless. (2) The return information can’t satisfy user’s search needs. (3) A huge number of trivial results are returned, make user difficult to distinguish them. In order to solve the problems given above, we propose a simplified algorithm for meaningful SLCA, experiment result shows that the algorithm is efficient, and it achieves a good balance in the precision and the recall.
|
2022-08-27T04:34:57.361Z
|
100,655,666 |
{
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"DOI": "10.2166/WS.2004.0120",
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|
Direct injection of nanoscale iron particles represents a promising technology for in-situ groundwater remediation. Nanoscale Pd/Fe particles have been shown an excellent performance for degradation of a wide array of contaminants in groundwater. The objective of this study is to investigate the nature of palladium on the reductive dechlorination of chlorinated ethylenes using nanoscale Pd/Fe particles. Kinetics analysis indicated that nanoscale Pd/Fe particles increased dechlorination rates by 1–2 orders of magnitude compared to nanoscale Fe particles alone. XRD analysis and activation energy measurement suggested that the increase of reaction rates can be attributed to the catalytic property of palladium.
|
2022-09-03T17:52:17.261Z
|
155,054,518 |
{
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"DOI": "10.2148/BENV.36.3.328",
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"url": null
}
|
Between 2006 and 2010 BRT systems in Australasia have increased by 216 route km (200%), mostly on established systems. There has been a significant rise in BRT ridership which increased from 37 million passengers per annum to 86 million passengers per annum. Most ridership growth occurred in systems which were already in operation in 2006. Analysis shows ridership growth on established BRT systems tracked consistently higher than transit ridership in general. Lessons in BRT implementation and development, together with the challenges presented by new technologies and patronage and operations growth are described. It is forecast that the future rate of BRT system growth is likely to slow compared with the last 4 or 5 years.
|
2022-09-06T13:18:12.990Z
|
3,279,303 |
{
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"DOI": "10.1159/000153274",
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}
|
Isoelectric focusing of the vitamin D binding globulin has demonstrated over 30 genetic variants. A study of 3,482 Caucasians demonstrated 4 individuals with a new variant cathodal to Gc1S. The new va
|
2022-09-12T03:49:23.703Z
|
236,532,023 |
{
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"DOI": "10.1002/smll.202101326",
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"url": null
}
|
Argyrodite Li6 PS5 Cl with high Li+ conductivity is a promising material for solid-state electrolytes (SSEs) in all-solid-state lithium batteries (ASSLBs). However, the narrow electrochemical window of Li6 PS5 Cl limits its applications in ASSLBs with high energy densities, and those that consist of high-voltage cathode materials and metallic lithium anodes. Unstable lithium deposition and stripping at interfaces is also a factor that restricts its industrialization. Herein, the authors investigated the electrochemical stability of Li6 PS5 Cl using it as both the cathode and electrolyte. The Li6 PS5 Cl-C/Li6 PS5 Cl/Li cell and symmetric Li/Li6 PS5 Cl/Li cells failed after a certain number of cycles, and subsequently healed electrochemically. This failure/healing phenomenon recurred during the cycling process. The self-healing behavior is closely related to the electrochemical window, which suggests that it can be controlled by the charge-discharge voltage range. In-depth X-ray photoelectron spectroscopy, in situ Raman spectroscopy, and in situ electrochemical impedance spectroscopy revealed the reversible Li6 PS5 Cl decomposition and metallic lithium growth inside the electrolyte during the cycling process. This self-healing behavior is mainly attributed to the reciprocating lithium growth and reversible redox reaction of the Li6 PS5 Cl decomposition. The proposed self-healing mechanism is a key aspect for sulfide-based SSEs, guiding the interface modification, and material design of ASSLBs.
|
2023-01-01T06:11:15.893Z
|
208,109,793 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICSCAN.2019.8878793",
"MAG": "2981990504",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Women now a days at their teen age they do endure the pain of taking treatment for the cancer in which they are equal to the pain of the death in order to avoid the fear of being treated for the cancer disease with the help of the existing data mining algorithm we can predict the occurrence and non-occurrence duration of the patient by envisaging the uterus cancer in the women we can avoid the number of death rate and the patients who have been treated for the cancer. However many people they even do not have the money to afford for their treatment so in order to help the poor and the wealthy people this paper aims to predict the occurrence and non-occurrence duration of the patient with the help of the following algorithm we can predict them they are of hidden markov model, neural network, linear filtering with the support of the big data. The prediction of the uterus cancer recurrence period is done by analyzing the image format health records of the patient.
|
2022-02-08T03:57:10.966Z
|
83,678,080 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.0022-3646.2003.03906001_73.X",
"MAG": "1984383030",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The Berkeley Pit in Butte, Montana is currently filled with 35 billion gallons of water, with 6 million gallons being added daily. The water in the pit contains a number of dissolved metals and other elements. These elements include: aluminum, iron, manganese, zinc, copper, cadmium, magnesium, nickel, calcium, sulfur, and silicon. Also, over 40 different types of small organisms live in the contaminated water. The purpose of this experiment is to examine the uptake potential of elements from Berkeley pit water by highly concentrated algal samples. The algae used are called Chlamydomonas acidophila. Chlamydomonas acidophila's optimum pH is between 3.5 and 4.5 and it may be capable of metal uptake by two mechanisms: absorption and adsorption. Adsorption and absorption are good alternatives to traditional wastewater treatments because algal cells are a naturally abundant renewable resource that can be cheaply produced. Algal cells are also highly selective in terms of removal and recovery of specific heavy metals, they do not require reagents, which typically cause disposal and space problems, and they require a relatively low initial capital investment with low operating costs. The experimental procedure involved using modified acid medium to grow algae from a stock solution to a concentration of 1.6×108 algae cells/mL. The growth medium was then washed from the algae cells. Three initial samples of sterile filtered pit water (SFPW) were set aside as a control. Then, concentrated algae cells were added to three centrifuge tubes. Next, SFPW was added to 3 tubes with algae and three tubes without algae. After 1 hour, a 5 mL sample was taken from each of the centrifuge tubes. After 24 hours, another 5 mL sample was taken from each of the centrifuge tubes. Inductively Coupled Plasma (ICP) analysis was performed on all the samples. The results from the initial SFPW were compared with those samples containing algae for 1 hour and 24 hours. Total metal uptake in 24 hours was roughly 7.81%.
|
2022-02-11T01:15:26.316Z
|
21,108,622 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3109/00313027209068952",
"MAG": "2112237632",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Summary The manifestations of septicaemic shock, just as in other forms of shock, revolve around microthrombosis of vessels on the venous side of the circulation, tissue necroses and haemorrhages. With gram‐negative septicaemic states, however, there is a much greater incidence of pulmonary haemorrhages than in other forms of shock and these haemorrhages may cause fatal respiratory insufficiency. If the patient lives long enough pneumonia usually supervenes.
|
2022-09-12T13:55:34.961Z
|
33,417,048 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/ntr/ntn028",
"MAG": "1985761007",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc2658900?pdf=render"
}
|
INTRODUCTION
Withdrawal is one of the most important symptoms of nicotine addiction. We examined the extent to which adolescent light smokers experienced withdrawal symptoms when deprived of nicotine for a 24-hr period.
METHODS
A total of 20 adolescents aged 13-17 years who smoked 1-5 cigarettes/day (CPD) refrained from smoking for a 24-hr period. Withdrawal scales were administered, and heart rate was measured at baseline, 12, and 24 hr. Neuropsychological testing was performed at baseline and 24 hr. Participants were divided into two groups: very light smokers (1-3 CPD) and light smokers (4-5 CPD).
RESULTS
At 12 hr, very light smokers experienced a decrease in withdrawal symptoms versus light smokers, who reported an increase in symptoms (-2.9 vs. 2.8, p = .02). Similarly, at 24 hr, very light smokers experienced a mean decrease in withdrawal score compared with a mean increase for the light smoker group (-2.2 vs. 5.8, p = .04). We did not find a significant change in heart rate or any differences in participants' scores on the memory or concentration tasks.
DISCUSSION
Based on our findings in this controlled laboratory experiment, adolescent very light smokers did not appear to have significant withdrawal symptoms following abstinence from nicotine. Adolescent light smokers who smoke 4-5 CPD experienced subjective withdrawal symptoms but did not have objective signs of nicotine withdrawal. The stage of smoking in which adolescents are smoking 5 CPD or fewer appears to be a crucial time for studying development of nicotine addiction in teens as they may be transitioning from social smoking to early addiction.
|
2022-12-16T12:38:11.979Z
|
80,955,505 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4266/acc.2018.00276",
"MAG": "2902813878",
"PubMedCentral": "6849032"
},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://www.accjournal.org/upload/pdf/acc-2018-00276.pdf"
}
|
Background: The purpose of this study was to evaluate the clinical application of modified Burns Wean Assessment Program (m-BWAP) scoring at first spontaneous breathing trial (SBT) as a predictor of successful liberation from mechanical ventilation (MV) in patients with endotracheal intubation. Methods: Patients requiring MV for more than 72 hours and undergoing more than one SBT in a medical intensive care unit (ICU) were prospectively enrolled over a 3-year period. The m-BWAP score at first SBT was obtained by a critical care nursing practitioner. Results: A total of 103 subjects were included in this study. Their median age was 69 years (range, 22 to 87 years) and 72 subjects (69.9%) were male. The median duration from admission to first SBT was 5 days (range, 3 to 26 days), and the rate of final successful liberation from MV was 84.5% (n=87). In the total group of patients, the successful liberation from MV group at first SBT (n=65) had significantly higher m-BWAP scores than did the unsuccessful group (median, 60; range, 43 to 80 vs. median, 53; range, 33 to 70; P<0.001). Also, the area under the m-BWAP curve for predicting successful liberation of MV was 0.748 (95% confidence interval, 0.650 to 0.847), while the cutoff value based on Youden’s index was 53 (sensitivity, 76%; specificity, 64%). Conclusions: The present data show that the m-BWAP score represents a good predictor of weaning success in patients with an endotracheal tube in place at first SBT.
|
2022-12-18T14:49:25.146Z
|
151,093,341 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1742-6596/1157/4/042130",
"MAG": "2922071939",
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://doi.org/10.1088/1742-6596/1157/4/042130"
}
|
Twenty-first-century skills usually are going neglected by several primary teachers (in-service teachers) in term of the learning process rather than students’ achievement. Though the implementation of information-acquisition theory this research aims to explore primary teachers’ perceptions toward 21st-century skills. The research method which was utilized as a case study with respondents was about tenth in-service primary teachers from five schools in Purwakarta city. The data were been collected through semi-structural interview and analyzed using grounded theory. The research results show that primary teachers need to comprehend 21st-century skills regarding develop primary students’ learning. Furthermore, they also explain the complexity of teachers which were facing and developing their 21st-century skills. As a consequence, this research promotes the educational training for primary teachers to develop twenty-first-century skills in primary context.
|
2022-08-20T13:51:30.891Z
|
245,628,992 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3746/pnf.2021.26.4.459",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBYNC",
"status": "HYBRID",
"url": "https://www.pnfs.or.kr/journal/download_pdf.php?doi=10.3746/pnf.2021.26.4.459"
}
|
Copyright © 2021 by The Korean Society of Food Science and Nutrition. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. ABSTRACT: Aronia, blueberry, Korean raspberry, blackberry, mulberry, and red raspberry fruits cultivated in Korea were evaluated for total phenol content (TPC), total flavonoid content (TFC), total anthocyanin, and ascorbic acid content. All berries were assayed for antioxidant activities determined as 2,2-diphenyl-1-picrylhydrazyl free radical scavenging activity, 2,2’-azino-bis(3-ethylbenzothiazoline)-6 sulphonic acid free radical scavenging activity, and ferric reducing antioxidant power. Individual phenolic compounds in aronia were also identified using high-performance liquid chromatography/ quadrupole-time of flight mass spectrometry. TPC, TFC, total anthocyanin, and ascorbic acid contents of the fruit samples ranged from 17.05 to 135.55 mg of gallic acid equivalent/g dry weight (dw), 1.0 to 8.59 mg of rutin equivalent/g dw, 2.55 to 24.43 mg of cyanidin-3-O-glucoside equivalent/g dw, and 3.14 to 19.45 mg of ascorbic acid equivalent/g dw, respectively. Aronia and Korean raspberry showed the highest TPC, TFC, and total anthocyanin while red raspberry had the highest ascorbic acid content. Antioxidant activities showed positive correlations to phenolic and anthocyanin contents suggesting antioxidant activity of berry samples is due to these compounds. Aronia had the highest antioxidant value among fruits.
|
2022-09-05T15:52:12.999Z
|
251,779,456 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3832/ifor4035-015",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://iforest.sisef.org/pdf/?id=ifor4035-015"
}
|
The nearest neighbor trees (NNTs) are essential for reflecting forest structure and spatial heterogeneity in a forest stand. It is not clear whether different tree species have varied patterns of NNTs in a small area due to biological interactions, whether big trees affect the nearest neighbors for diversity and re-cruitments, or whether a universal linear relationship between the distance of NNTs and their average DBH exists. In this study, the information of NNTs at two plots (each 30 × 100 m) in a temperate mixed broadleaved forest in Southern USA was collected by field survey. Our results indicated that approximately 80% of NNTs were within a distance of 1.5-4.0 m. Tulip poplar, oaks, and hickory trees did not have the same species as NNTs or were very limited. Carolina buckthorn had itself as an NNT but with fewer other species. Sugar maple could serve as the NNT for oaks, hickory and others. The relationships between the distance of an NNT and its cumulative percentage were different among varied species or groups. Overall, for trees and their NNTs, there existed complicated relationships between their sizes ( e.g. , height and DBH). Big trees might affect NNTs in diversity and recruitment. The suggested linear relationship between tree size and distance was not observed. The results could be helpful to manage forest structure (tree species and NNT) and provide evi-dence to improve the scaling theory on NNTs.
|
2022-09-09T04:58:21.208Z
|
212,463,040 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.12980/apjtd.7.2017d6-326",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://doi.org/10.12980/apjtd.7.2017d6-326"
}
|
Qazi Azad-uz-zaman, Quazi Zahangir Hossain, Md. Abdullah Al Hadi, Jiptha Boiragee, Masuma Parvin Japan Association of Drainage and Environment, House-6, Road-2, Nirala R/A, Khulna-9100, Bangladesh Environmental Science Discipline, Life Science School, Khulna University, Khulna, Post Code-9208, Bangladesh The Leprosy Mission International Bangladesh, Mohakhali DOHS, Dhaka-1206, Bangladesh Asian Pac J Trop Dis 2017; 7(1): 25-29
|
2022-10-14T17:12:55.087Z
|
53,443,774 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/ijsa.12118",
"MAG": "1822168192",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://openaccess.city.ac.uk/id/eprint/15945/1/IJSA_12118.pdf"
}
|
This article presents results from two samples of applicants (total N = 368) for general practitioner posts in the United Kingdom. The roles of job relatedness and self‐efficacy in fairness perceptions were explored, with data gathered at two time points: immediately after testing and one month later following outcome (pass/fail) feedback. Overall, results indicated that in two samples, job relatedness perceptions measured at the time of testing predicted fairness perceptions measured following outcome feedback. In addition, the stage in the selection process (shortlisting vs. assessment center) was important in determining the extent to which job relatedness perceptions predicted fairness. Findings also suggest that self‐efficacy may be a predictor, rather than an outcome variable, in applicant fairness perceptions in this high‐stakes setting. Results are discussed in relation to their practical and theoretical implications.
|
2022-12-17T22:08:08.023Z
|
72,582,057 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1590/S0004-282X1948000200005",
"MAG": "2065734428",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The authors, going through the literature on ophtalmoplegie migraine, point out the difference of opinions concerning its existence or not and its physiopathology. They present two cases. Both had a rich symptomatology characterizing the attacks of migraine (more or less rapid onset of the headache localized to one hemicranium and folowed by neurovegetative signs, vomiting and fotofobia). Both cases showed, in the electroencephalogram, bilateral symetrical paroxysmal dysrhythmia indicating a true migraine in patients without epileptic seizures and without an epileptic familial background. The ophtalmoplegia usually followed the most severe attacks of headache with total involvement of the third pair, lasting one to thirty or more days. Based in these two cases where attacks of migraine (localized cerebral oedema) were followed by repetitive troncular palsy of the ipsilateral third pair, the authors think to be able to adopt Foster-Kennedy's theory (compression of the nervous trunk by the oedematous brain) and to accept the existence of a true ophtalmoplegic form of migraine in the sensus of Charcot.
|
2022-12-30T00:59:36.349Z
|
234,923,357 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2139/SSRN.3784973",
"MAG": "3154260761",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Problem definition: We study implications of government financing to promote clean technology development, which provides loans for financially constrained firms that manufacture and sell clean-technology products. Methodology/results: We build an analytical model to explore the impact of such government financing in the presence of market uncertainty. Our analysis shows that government financing results in the firm's more aggressive technology investment and exposes the firm to a higher bankruptcy risk. We also provide empirical evidence based upon the clean-technology projects financed by loan programs under the U.S. Department of Energy to support this analytical result. To deal with the high bankruptcy risk under government financing, we propose a risk-mitigating mechanism where the government utilizes a more sophisticated loan contract that ties the firm's environment commitment and quantity commitment in such a way that discourages the firm's over-investment in technology. Managerial implications: Our work sheds light on the overlooked risk associated with government financing for clean technology development, and provides rationales for some of the high-profile bankruptcies of the financed firms.
|
2022-02-07T21:28:48.041Z
|
88,000,346 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/AESA/80.1.100",
"MAG": "2321941052",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A new species of scale insect, Cerococcus mirandae Lambdin, from Australia, is described and illustrated. C. mirandae represents the seventh species in the genus from the Australian Region and is distinguished from other species in the genus by the presence of 6-locular pores in transverse abdominal rows on the venter. A key is provided to separate species of Cerococcus of the Australian Region.
|
2022-02-10T20:55:27.063Z
|
28,387,958 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4992/JJPSY.75.246",
"MAG": "2314031152",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The purpose of this study was to examine the influence friends had on academic competence of children. Junior high school students, 322 in total, participated in the study. Results essentially replicated previous studies on the relationship between academic achievement and perceived academic competence, and it was positive. The present study also found that when the friendship was close and reciprocal, the achievement-competence relationship was strong if the friend's achievement was low, and weak if it was high. In contrast, children's perception of academic competence was not influenced if the comparison of academic achievement was made with a friend who was not very close.
|
2022-02-12T14:24:17.970Z
|
250,908,427 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/0256-307X/24/12/028",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Anisotropic flows (v1, v2, v3 and v4) of light fragments up to the mass number 4 as a function of rapidity are studied for 25 MeV/nucleon 40Ca + 40Ca at large impact parameters by a quantum molecular dynamics model. A phenomenological scaling behaviour of rapidity dependent flow parameters vn (n = 1, 2, 3 and 4) is found as a function of mass number plus a constant term, which may arise from the interplay of collective and random motions. In addition, v4/v22 keeps to be almost independent of rapidity and remains a rough constant of 1/2 for all light fragments.
|
2022-07-31T12:04:26.400Z
|
46,956,225 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/IWCE.2000.869900",
"MAG": "2132645065",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We performed a single-electron Monte Carlo simulation to study the magnetic field dependence of the drift-velocity, v/sub drift/, for the miniband transport regime in a GaAs/AlAs superlattice. Using a realistic model of scattering, the calculated v/sub drift/-electric field characteristics are compared with the experimental results.
|
2022-11-05T13:20:28.063Z
|
31,914,922 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/MUE.2007.20",
"MAG": "2164244956",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Trust is a fundamental issue in multi-agent systems, especially when they are applied in E-Commerce. The computational models of trust play an important role in determining who and how to interact in open and dynamic environments. To this end, a computational trust model is proposed in which agents can autonomously deal with the biased information and identify trust belief with aging factor in multi-agent systems.
|
2022-12-12T09:25:00.601Z
|
55,575,656 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/app8081255",
"MAG": "2885228713",
"PubMedCentral": "7323930"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2076-3417/8/8/1255/pdf"
}
|
We demonstrated the capability of quantitative optical coherence elastography (qOCE) for robust assessment of material stiffness under different boundary conditions using the reaction force and displacement field established in the sample.
|
2022-12-20T03:52:13.815Z
|
7,227,989 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/00002800-199509000-00009",
"MAG": "2075929957",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
THE STUDY EXAMINES 125 labels central to nursology used by practicing nurses to describe patients. Each nurse described the response pattern identified by each label, organizing and prioritizing its characteristics to produce a diagnostic algorithm. After work-peer affirmation of the chart's accuracy, the response pattern was renamed as a “syndrome.” Predominant characteristics of each syndrome were analyzed. Nurses developed treatment protocols that they believed would reduce, control or “cure” denning characteristics. Field testing of these protocols demonstrated that conditions identified by labels (which normally lead to nurse avoidance) could be effectively treated when approached proactively. Some syndromes involved response patterns related to medical diagnosis or treatment, specific units in the hospital or the health care system itself. Nursology also includes less-than-ideal responses to circumstances that threaten personal well-being.
|
2022-02-13T09:15:27.080Z
|
57,958,792 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.14705/RPNET.2015.000342",
"MAG": "2283902816",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper introduces a case course with videoconferencing as a way of Synchronous Computer Mediated Communication (SCMC) for foreign language education in Japan. Research questions were to see the effects of videoconferencing on the learners’ speaking ability and general English language proficiency, and also to see how the learners’ international posture changed over time. Eight pairs of Japanese university English as a Foreign Language (EFL) learners experienced two semesters of 9-10 videoconferencing sessions per semester with an English teacher living in the Philippines. The task for the pairs was to discuss a social issue together with the teacher once a week. Their goal was to exchange mutual ideas on the designated topic. To lower the anxiety of speaking English as well as to practice discussion with fellow Japanese students, there was a 90-minute preparation period prior to each videoconferencing session. Pre-tests and post-tests results showed significant improvement in fluency, particularly in the amount of speech, and complexity of their speaking abilities. The learners also demonstrated progress in English proficiency. Their international posture stayed at a high level, but did not change much. However, their increased interest in working or participating in volunteer activities overseas was observed. The results indicated that the instruction based on videoconferencing helped improve learners’ language and their global mind as a part of international posture.
|
2022-08-29T13:07:33.253Z
|
27,359,685 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1136/bmj.1.5070.573",
"MAG": "2016557030",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc2027918?pdf=render"
}
|
Most children are medically examined at least three times during their school life. This is a matter of routine, whether they are ill or not. The examinations, known as the i periodic medical inspections," are made by the School Health Service. Further, under the system of compulsory national service which has been in force since 1939, a large proportion of boys aged 18 are medically examined to determine their fitness for service with the armed Forces. The rejection rate because of physical and mental defects is about one in five. In view of this, it seemed interesting to try to relate the findings of these pre-service examinations to those of the school doctors, who usually make their last examination between three and four years earlier. There was available from another study (Lee, 1957) copies of the records of a series of these medical examinations made before national service, and a group of these were matched with the records of the School Health Service dealing with the same individuals. It was at once clear that there were few important defects recorded by the school doctors that were not also noted at the pre-service examination. But there were many defects leading to rejection that were not mentioned on the records of the School Health Service. This disagreement was not limited to defects that might have been expected to arise for the first time between the medical examinations of school leavers-mostly during the fifteenth year-and the medical examinations before national service-mostly during the early months of the nineteenth year. The findings of this pilot inquiry raised questions about the effectiveness of the periodic medical inspections as a means for the detection of important disease in schoolchildren. After consultation with the Ministry of Education, which is the central department responsible for the School Health Service in England and Wales, a further inquiry on similar lines and on a larger scale was undertaken. The number of men who are accepted for national service and then found to have serious defects is very low (Brit. med. J., 1956), and as there was thus no reason to believe that many defects were missed at the pre-service examinations, the further studies were limited to those who were rejected for service on medical grounds.
|
2022-09-06T06:46:15.047Z
|
28,917,006 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1055/S-0037-1613213",
"MAG": "2413176650",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Inhibition of Human Osteoblast Growth by Unfractionated Heparin and by Low Molecular Weight Heparins in vitro -
|
2022-09-09T03:48:34.140Z
|
24,352,156 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1006/ENRS.1994.1041",
"MAG": "1998941609",
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},
"license": null,
"status": null,
"url": null
}
|
The association between early lead exposure and later problem behaviors was evaluated prospectively in a cohort of 8-year-old children born during a 12-month period at one hospital. Lead levels in umbilical cord blood (means = 6.8 micrograms/dl, SD = 3.1) and the dentin of a shed deciduous tooth (means = 3.4 micrograms/g, SD = 2.4) provided measures of prenatal and postnatal exposure, respectively. Ratings on the Teacher Report Form of the Child Behavior Profile provided information about children's problem behaviors. Cord blood lead level was not associated with the overall prevalence or nature of problem behaviors. In both crude and adjusted analyses, tooth lead level was significantly associated with total problem behavior scores (approximately 2 points in T score per log unit increase in tooth lead). Significant tooth lead-associated increases in both internalizing and externalizing scores were also observed (approximately 1.5 points in T score per log unit increase). Weaker associations were noted between tooth lead level and the prevalence of "extreme" problem behavior scores. The extent to which these associations reflect residual confounding is uncertain. These data suggest, however, that social and emotional dysfunctions are correlates and may be expressions of increased lead exposure.
|
2022-12-18T23:55:25.431Z
|
234,601,215 |
{
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"DOI": "10.18778/2299-8403.09.06",
"MAG": "3128345655",
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"license": "CCBYNCND",
"status": "GOLD",
"url": "https://czasopisma.uni.lodz.pl/biuletynuniejowski/article/download/8533/8401"
}
|
Celem artykułu jest ocena zmian dostępności pieszej i rowerem, kluczowych przestrzeni publicznych w Uniejowie, na przykładzie kładki pieszej na Warcie. Przestrzenie publiczne, to miejsca pełniące szereg funkcji zarówno w sferze ekonomicznej, jak i społecznej. Ich szczególną cechą jest dostępność, która będzie stanowiła przedmiot rozważań niniejszego opracowania. W pracy posłużono się metodą izochron, aby ukazać zmiany powierzchni zabudowy jedno- i wielorodzinnej, w przyjętych przedziałach czasowych. Wykazuje ona jak ważnym elementem w kształtowaniu dostępności, dla użytkowników przestrzeni publicznych, może być kładka piesza.
|
2022-12-23T02:19:05.804Z
|
237,640,445 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.3892/etm.2021.10701",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://www.spandidos-publications.com/10.3892/etm.2021.10701/download"
}
|
Human papillomavirus (HPV) is one of the most widespread human pathogens. For a long time, it was treated as an opportunistic infection, but it is in actuality one of the most dangerous carcinogens. It is responsible for numerous malignancies: Cervical, penile, oropharyngeal, vaginal, vulvar and some anal neoplasia. The need for a long-term solution was evident and thus HPV vaccines were proven to be a viable solution. Women and men who have sex with men, and young men are included in the vaccination template. A thorough review using PubMed and other databases that included articles on vaccine templates and targeted male patients was carried out. After review of all of the studies conducted on this subject, there is a clear benefit for HPV vaccination for men. Yet, even with the introduction of a national vaccine program for HPV for women and girls in most developed countries, regarding the male vaccine program, few countries have established a national program. Still, a gender-neutral vaccine remains a controversial issue. It is important to monitor the impact of HPV vaccine in men and the benefits that occur, to inform and spread the results in order to implement this vaccine program worldwide. Any monitoring plan regarding the HPV vaccination must include HPV prevalence, anogenital warts, and anal cancer. The largest impact regarding the range of this type of vaccine is the surveillance of the specific targeted population. HPV vaccine is a very efficient immunization method. Women are obviously the first target, but there are still many contradictions regarding men. Most of the reasons reside in the cost-efficiency aspect, but there is still great debate regarding the most efficient vaccine in the male population.
|
2022-12-26T06:11:31.637Z
|
55,983,878 |
{
"externalids": {
"ACL": null,
"ArXiv": "1304.3643",
"DOI": "10.1103/PhysRevB.88.121101",
"MAG": "2103832487",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We show that an interlayer exciton condensate doped into a strongly correlated Mott insulator exhibits a remarkable enhancement of the bandwidth of the magnetic excitations (triplons). This triplon is visible in the dynamical magnetic susceptibility and can be measured using resonant inelastic x-ray scattering. The bandwidth of the triplon scales with the exciton superfluid density, but only in the limit of strong correlations. As such the triplon bandwidth acts as a probe of exciton-spin interactions in the condensate.
|
2022-12-30T01:01:54.909Z
|
78,351,662 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1056/PA201104270000005",
"MAG": "2599165977",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In a randomized clinical trial, researchers compared the effectiveness of a 6-month child-centered physical-activity program, a parent-centered dietary-modification program, or both interventions in 165 prepubertal overweight children (age range 5.5–9.9 years) in Australia. Both interventions included weekly 2-hour face-to-face sessions for …
|
2022-02-11T04:51:07.892Z
|
244,801,715 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1145/3481127.3481156",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
∗The development of a world-class manufacturing innovation ecosystem is key to the development of a high-quality Chinese manufacturing industry. This study contributes to existing knowledge by clarifying the concept and proposing the integrated conceptual framework for a world-class manufacturing innovation ecosystem. Notable theoretical and practical implications are provided for the ecosystem stakeholders to win world-class competitions.
|
2022-09-01T11:33:42.220Z
|
44,372,619 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/003591573002300869",
"MAG": "1748564597",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://journals.sagepub.com/doi/pdf/10.1177/003591573002300869"
}
|
tubercle bacilli had never been present in such a person's tissues. If further data which we are collecting (and we hope others will collect data along these lines) show that these results are not merely accidental, we will have to searcb for an explanation. It may be that a tuberculous invasion, present or past, in some way tends to prevent or delay the development of a malignant growth in old age. It may be that the type of tissue which can successfully overcome a tuberculous lesion is also the type which can control, more successfully than the tissues in the tuberculosis negative cases, cells that are tending to become cancerous and invasive. If the tuberculous invasion, successfully overcome, has added to the individual's make-up some anti-cancerous factor, this may open the way to the detection of other measures by which added resistance to the development of malignant growths may be established.
|
2022-09-11T13:08:01.456Z
|
22,296,345 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1108/13673270710752108",
"MAG": "1985260934",
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},
"license": null,
"status": null,
"url": null
}
|
– The purpose of this paper is to investigate the influence of a relationship marketing orientation within a strategic alliance (referred to as the Alliance) to determine whether those firms have achieved synergy in knowledge sharing or whether they operate as knowledge silos., – To achieve this aim the paper takes a strategic perspective and proposes a model based on the resource‐based view of the firm (RBV) in order to discover whether member firms can move Alliance relationships towards knowledge sharing experienced within long‐term and continuing relationships., – The results of this study reveal that intangible assets, such as relationships and knowledge, should be managed by the Alliance with the same care as would be undertaken with tangible assets. Further, the development of a relationship market orientation (RMO) by the Alliance appears to be crucial., – A key limitation of this paper could be considered the sample size (although the response rate was high) and geographical location., – Implications from the study were that, although information and knowledge were being shared, one area of improvement would be in relation to the depth of knowledge sharing that tended to occur on a superficial basis., – The findings are original in terms of knowledge sharing across organizational boundaries. There is currently very little research available that focuses on the influence of an RMO on knowledge sharing within network groups.
|
2022-11-18T18:40:59.469Z
|
218,980,020 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.36227/techrxiv.12367508.v1",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBYNCSA",
"status": "GREEN",
"url": "https://www.techrxiv.org/articles/preprint/Fast_Recovery_Mechanisms_in_the_Data_Plane/12367508/files/22798424.pdf"
}
|
In order to meet their stringent dependability requirements, most modern communication networks support fastrecovery mechanisms in the data plane. While reactions to failures in the data plane can be significantly faster compared to control plane mechanisms, implementing fast recovery in the data plane is challenging, and has recently received much attention in the literature. This tutorial presents a systematic overview of packet-based fast-recovery mechanisms in the data plane, focusing on concepts but structured around different networking technologies, from traditional link-layer and IPbased mechanisms, over BGP and MPLS to emerging softwaredefined networks and programmable dataplanes. We examine the evolution of fast-recovery standards and mechanisms over time, and identify and discuss the fundamental principles and algorithms underlying different mechanisms. We then present a taxonomy of the state-of-the-art and compile open research questions.
|
2022-12-17T15:13:45.789Z
|
3,657,943 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/ICO.0000000000001558",
"MAG": "2792086418",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Purpose: To explore the effectiveness of “off-the-shelf” dipotassium-ethylenediaminetetraacetic acid (K2-EDTA) as an alternative to sodium EDTA as chelation therapy in removal of calcific band keratopathy (CBK). Methods: This study was a retrospective case series involving 4 patients with CBK who underwent superficial keratectomy and subsequent chelation therapy with K2-EDTA in a single center (Coastal Eye Clinic) by the same surgeon. Visual acuity and symptomatic relief were the main outcomes measured in our study. Results: All 4 participants in this study were female with an average age of 80.3 years. Three of the patients with reasonable baseline visual acuity experienced improved visual acuity at 1 month. The other patient with multiple ocular comorbidities and severely reduced visual potential reported symptomatic pain relief at 1-month follow-up after the intervention. Conclusions: K2-EDTA seems to be an effective alternative to disodium EDTA in its ability to clear calcific plaques and restore visual function. Because of the logistical difficulties associated with acquiring disodium EDTA, and the relative abundance of K2-EDTA in health-care facilities, we believe that our findings warrant further investigation into its use as a more accessible and cost-effective chelating agent in CBK.
|
2022-12-24T18:06:38.633Z
|
228,265,351 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3760/CMA.J.ISSN.1674-2907.2013.19.011",
"MAG": "3030350966",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Objective To study the influence of empathy nursing on depressive emotion and life function of glioma patients with depression.Methods Totals of 94 glioma patients with depression between April 2006 and December 2012 were divided into two groups.Fifty-one cases in the experimental group accepted empathy nursing,while 43 cases in the control group accepted regular nursing.Compared and analyzed the Hamilton depression scale (HAMD) score,nurses' observation scale for inpatient evaluation (NOSIE) score and satisfaction for the nursing job of the two groups.Results Before the intervention,difference of HAMD score between two groups was not statistically significant [(27.1 ± 5.2) vs (26.9 ± 5.0) ; t =0.190,P ＞ 0.05].After the intervention,HAMD score of the experimental group was obviously better than that of the control group [(16.3 ± 2.9) vs (21.1 ± 2.5) ; t =8.618,P ＜ 0.05].Before the intervention,the difference of social competence,social interest,personal hygiene and depression scores between the two groups was not statistically significant [(16.29±3.18),(17.52 ±3.48),(13.98±2.84),(10.24 ±2.12) vs (16.43 ±3.07),(17.56 ±3.63),(14.13 ±2.91),(10.29 ±2.23);t=0.217,0.054,0.252,0.111;P＞0.05)].After the intervention,the above ratings of experimental group was significantly better than that of the control group [(9.81±2.08),(8.69±1.87),(6.61 ±1.97),(4.82 ±1.37) vs (13.29 ±1.94),(12.63 ±2.58),(8.84 ± 2.35),(6.98 ± 1.99) ; t =8.382,8.337,4.931,6.016 ; P ＜ 0.05)].The total score of nursing job satisfaction in the experimental group was significantly better than that of the control group [(120.59 ± 9.48) vs (112.78 ± 10.05) ; t =3.852,P ＜ 0.05)].Conclusions Empathy nursing can improve the depressive emotion and life function of glioma patients with depression,which can also improve the satisfaction of patients with the nursing job.
Key words:
Glioma; Depression; Empathy nursing
|
2022-01-27T10:54:11Z
|
15,790,983 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/SITIS.2009.84",
"MAG": "2140454105",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Assessing the risk associated to structured financial products such as collateralized debt obligations, involves processing information about diverse risk factors: some information comes from the different sources directly in aggregated form, therefore it is not possible to estimate the correlation among different risk components. In this paper we address the problem of assessing the credit risk associated to a borrower or to a security by privacy preserving methods. Specifically we suggest use Secure Multiparty Computation to merge the information from the different sources so as to compute more accurately the overall risk profile of securitized assets, without disclosing the information from each individual source.
|
2022-08-25T02:35:38.678Z
|
45,540,049 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2519/JOSPT.1999.29.6.316",
"MAG": "2108811367",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
STUDY DESIGN
Observational study of static and dynamic foot postures in professional baseball players.
BACKGROUND
Throughout the course of a professional baseball season, running, cutting, and sprinting activities can produce a breakdown in players' foot function, causing overuse injuries.
OBJECTIVES
To investigate the relationship between static and dynamic foot postures; to determine the occurrence of abnormal foot postures in professional baseball players and the incidence of overuse injuries in the lower extremity; and to compare the foot postures of pitchers to those of positional players.
METHODS AND MEASURES
The foot postures of 74 professional baseball players were evaluated at rest and during gait. Measures of static foot posture were obtained with a goniometer and included the subtalar neutral position, forefoot/rearfoot position, ankle joint dorsiflexion, tibial angle in standing, and calcaneal angle in standing. The FootTrak motion analysis system provided measures of dynamic foot posture (rearfoot supination and pronation) during the stance phase of gait. A questionnaire was completed by players who reported previous lower extremity injuries. The chi-square statistic was used to determine the associations between forefoot position (varus or valgus) and the amount of foot pronation during gait.
RESULTS
The forefoot varus and calcaneal valgus in standing was significantly associated with the maximum pronation during the stance phase of gait. Of the 65 players who demonstrated excessive pronation (> 8 degrees), 28 (43%) also reported a previous lower extremity injury. No statistically significant difference occurred, however, between injured and uninjured players with respect to the mean values of static or dynamic foot posture. In addition, foot postures were not associated with a player's position.
CONCLUSIONS
Selected measures of static rearfoot and forefoot postures may have value in predicting dynamic rearfoot movement during the stance phase of gait. Excessive pronation in the baseball players we studied was not found to be a significant contributing factor in the development of overuse injuries.
|
2022-09-13T17:44:30.289Z
|
32,807,175 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3760/CMA.J.ISSN.1009-2587.2015.02.003",
"MAG": "2401386711",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
OBJECTIVE
To evaluate the therapeutic effects of VSD combined with irrigation of oxygen loaded fluid on the growth of granulation tissue and macrophage polarization in chronic venous leg ulcers.
METHODS
Thiry-four patients with chronic venous leg ulcers hospitalized in our department from December 2010 to July 2014 were divided into VSD group ( A, n = 11) , VSD + irrigation group ( B, n = 11) , and VSD + oxygen loaded fluid irrigation group ( C, n = 12) according to the random number table. After admissian, debridement was performed, and granulation tissue in the center of the wound was harvested during the operation. After dehridement, the patients in group A were treated with VSD only (negative pressure from -30 to -25 kPa, the same below) ; the patients in group B were treated with VSD combining irrigation of normal saline; the patients in group C were treated with VSD combining normal saline loaded with oxygen irrigation (flow of 1 L/min) . On post treatment day (PTD) 7, the VSD devices were removed. Cross observation was conducted before debridement and on PTD 7. On PTD 7, the granulation tissue in the center of the wound was harvested for histopathological observation with HE staining and Masson staining, following calculation of granulation tissue coverage rate. After debridement but before the negative pressure therapy (hereinafter referred to as before treatment) and on PTD 7, partial pressure of oxygen of the skin around the wound was measured by transcutaneous tissue oxygen tension survey meter. On PTD 7, expression of vascular endothelial growth factor (VECF) was determined with immunohistochemistry. Before treatment and on PTD 7, cells with double positive expressions of induced nitric oxide synthase plus CD68 ( type I macro- phage) and arginase 1 plus CD68 ( type II macrophage) were observed with immunofluorescence staining and quantified. Data were processed with Fisher's exact test, one-way analysis of variance, covariance analysis, paired test, and LSD test.
RESULTS
(1) The gross observation showed that before debridement there was a certain amount of necrotic tissue and little granulation tissue in the wounds of patients in all the 3 groups. On PTD 7, new granulation tissue was found in the wounds of patients in all the 3 groups, and in group C its amount was the largest. (2) On PTD 7, the granulation tissue coverage rate of wounds in pa- tients of group C was higher than that of group A or B ( P <0.05 or P <0.01). (3) On PTD 7, HE staining showed that there appeared more abundant new born microvessels and fibroblasts in the wounds of patients in group C than those in groups A and B; Masson staining showed that there was more abundant fresh collagen distributed orderly in the wounds of patients in group C compared with group A or B. (4) On PTD 7, it was found that partial pressure of oxygen of the skin around the wounds in patients of group C [(40.7 +/- 4.1) mmHg, 1 mmHg = 0.133 kPa] was higher than that of group A [ (35.0 +/- 3.1) mmHg] or B [(35.4 +/- 2.7) mmHg, with P values below 0.01]; the partial pressure of oxygen of the skin around the wounds of patients in all the 3 groups was increased significantly compared with that before treatment (with values from 10.38 to 22.52, P values below 0.01). (5) On PTD 7, the expression of VECF in the wounds of patients in group C was higher than that in group A or B ( P <0.05 or P < 0.01). (6) On PTD 7, the number of type I macrophages in granulation tissue of patients was respectively 14.3 +/- 2.3, 11.5 +/- 3.0, and 10.7 +/- 2.3 per 400 times vision field in groups A , B, and C ( F = 25.14, P < 0.01), while the number in group C was less than that in group A or B ( P < 0.05 or P < 0.01). Compared with that before treatment, the number of type I macrophages was significantly decreased on PTD 7 in all the 3 groups (with values from 14.76 to 23. 73, P values below 0. 01). On PTD 7, the number of type II macrophages in granulation tissue of patients was respectively 32.7 +/- 3.2, 35.1 +/- 3.3 , and 41.3 +/- 3.2 per 400 times vision field in groups A, B, and C ( F = 81.10, P < 0.01), and the number in group C was lager than that in group A or B ( with P values below 0. 01). Compared with that before treatment, the number of type II macrophages in all the 3 groups was significantly increased (with t values from -69.34 to -47.95, P values below 0.01).
CONCLUSIONS
VSD combined with irrigation of oxygen loaded fluid can raise the partial pressure of oxygen of the skin around the wounds effectively, promoting the transition of macrophages from type I to type II, thus it may promote the growth of granulation tissue, resulting in a better recipient for skin grafting or epithelization.
|
2022-09-22T14:05:22.838Z
|
34,392,604 |
{
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"DOI": "10.5326/0430132",
"MAG": "2189478130",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Epidural spinal myelolipoma was diagnosed in a 13-year-old, male Siberian husky that was referred for evaluation of progressive pelvic limb paresis and urinary incontinence. An epidural mass was detected by magnetic resonance imaging and computed tomography. The mass was removed and identified histopathologically as an epidural myelolipoma. Pelvic limb paresis improved after surgery, but urinary retention associated with neurological bladder dysfunction persisted.
|
2022-12-03T15:48:15.485Z
|
2,473,015 |
{
"externalids": {
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"DOI": "10.1111/j.1751-1097.1993.tb02322.x",
"MAG": "2006436439",
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},
"license": null,
"status": null,
"url": null
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|
A system for time‐gated fluorescence imaging was used to perform measurements on tumor‐bearing mice treated with hematoporphyrin derivative (HpD). The aim of the study was to define the potential of this technique in the diagnosis of tumors by taking advantage of the long fluorescence lifetime of the exogenous dye with respect to the decay times of the natural fluorescence. After the administration of three different drug doses (5, 10 and 25 mg/kg body weight), fluorescence images were acquired at various uptake times (from 2 h to 10 d), to determine the best instrumental conditions and experimental procedure for the detection of tumors in the murine model considered. The optimal fluorescence contrast between the tumor area and the surrounding healthy tissue was found at 12 h after the administration of either 5 or 10 mg/kg HpD and was anticipated at 8 h for the highest drug dose. In this optimum condition, the tumor region could be identified even after the injection of 5 mg/kg HpD. A better fluorescence contrast was always obtained in 15 ns‐delayed images with respect to synchronous ones.
|
2022-12-17T05:23:26.431Z
|
53,651,036 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.20955/R.52.12-24.KDR",
"MAG": "1552853330",
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},
"license": null,
"status": null,
"url": null
}
|
Fiscal policy — I’ede,’al Governumen!. spending and taxing programs was given time dominant. role in economic stabilization efforts during the decade of tire 1960’s. The income tax cut of 1964 was designed to accelerate time movement toward full employment after about three yea’s of what was considered by some a rather slow rate of economic expansion following the recession of 1960—61. The income tax surcharge and a rednction in the rate of increase in Government spending we’re adopted in 1968 to curb the inflation of the last half of the 1960’s.
|
2022-12-21T17:50:44.102Z
|
18,946,268 |
{
"externalids": {
"ACL": null,
"ArXiv": "dg-ga/9511005",
"DOI": "10.1090/trans2/179/07",
"MAG": "1694770817",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "http://www.ams.org/trans2/179/trans2179.pdf"
}
|
Global deformations of surfaces, immersed into the Euclidean 3-space, by using the modified Novikov--Veselov equation are investigated. relation to the theory of the Willmore functional is discussed
|
2022-12-25T18:23:29.338Z
|
18,338,052 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1242/jcs.116392",
"MAG": "1972825083",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
Cancers are not just masses of malignant cells but complex ‘rogue’ organs, to which many other cells are recruited and can be corrupted by the transformed cells. Interactions between malignant and non-transformed cells create the tumor microenvironment (TME). The non-malignant cells of the TME
|
2023-01-01T20:04:03.804Z
|
202,581,617 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5177/ntvt.2019.09.19069",
"MAG": "2973183368",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Although composite and indirect restorations have been used for many years in oral care, clinical studies of the survival rates of restorations placed by general practitioners are lacking. The most important objective of this doctoral research was to investigate the influence of possible risk factors related to practice/operator, patient and tooth/restoration on the longevity of direct restorations. A large database of electronic patient files of general practitioners within the Practice-Based Research Network Nijmegen (PBRN) enabled us to answer these research questions. Practitioners within the PBRN placed restorations with a mean longevity of 12 years, but considerable differences existed among practitioners. Individual patient risk factors such as general health, periodontal status,risk of bruxism and especially caries risk play a major role in restoration failure. Restorations in molars, restorations with multiple treated surfaces and restorations placed in endodontically treated teeth show greater risk for restorative intervention.
|
2022-01-27T02:03:02.221Z
|
125,885,700 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.31884/jtt.v4i2.122",
"MAG": "2895790712",
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},
"license": "CCBYSA",
"status": "GOLD",
"url": "https://jurnal.polindra.ac.id/index.php/jtt/article/download/122/pdf"
}
|
Valve (katup) sebagai salah satu produk industri, sangat dibutuhkan oleh perusahaan yang bergerak mengontrol aliran cairan untuk efisiensi. Kebutuhan tentang ini banyak digunakan oleh perusahaan makanan, obat-obatan, minuman, pembangkit listrik dan industri minyak dan gas. Tujuan penggunaan valve adalah untuk membatasi dan mengontrol cairan pada kondisi tekanan tinggi. Salah satu katup yang sering digunakan adalah ball valve, yaitu katup dengan tipe gerak memutar. Adanya permintaan ball valve ini, dibutuhkan produk dengan spesifikasi tertentu memiliki rancangan dengan tingkat kekuatan yang baik. Dengan kata lain, produk valve (katup) yang baik, harus memiliki kekuatan yang baik, aman dan sesuai dengan kebutuhan dilakukan pengujian. Penelitian ini bertujuan untuk melakukan analisis terhadap ball valve 4 inch ANSI 300 untuk memastikan katup yang diproduksi sesuai spesifikasi, kuat dan tahan terhadap tekanan fluida. Metode yang digunakan adalah Finite Element Analysis (FEA) dengan software Solidworks. Analisis dilakukan pada ball valve 4 inch ANSI 300 dengan keadaan full open, hall open dan full closed serta dengan pembebanan 725 psi dan 1087.5 psi hasil dari Computational Fluid Dynamics (CFD). Analisis dilakukan pada temperatur -29.50C, 250C dan 4250C. Berdasarkan hasil analisis dengan FEA, dinyatakan bahwa ball valve 4 inch ANSI 300 kuat dan aman untuk digunakan. Nilai faktor keamanan (safety factor), signifikan lebih tinggi dari nilai safety factor minimum yang diizinkan.
|
2022-04-13T03:25:04.515Z
|
86,848,060 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/MACP.1972.021580101",
"MAG": "2115305673",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Circular dichroism (CD) of solutions of soybean trypsin inhibitor (STI), papain, and an acid mold protease (from Rhizopus chinensis) was determined in the presence and absence of sodium dodecyl sulfate (SDS). The CD bands in the 240–320 nm spectral zone were almost completely eliminated by SDS. This indicated that the tertiary folding was disturbed and the restrictions imposed on the aromatic chromophores were largely removed. The CD bands in the far UV were modified by SDS in a manner that indicated increase of the α-helix content in these proteins. This specific type of denaturation has been observed also on many other proteins. The term reconstructive denaturation is suggested for this type of denaturation in which the helix content of the polypeptide chain is enhanced by the denaturing agent.
Der Circulardichroismus (CD) der Losungen des Trypsin-Inhibitors (STI) (aus Sojabohnen), von Papain und einer Protease aus Rhizopus chinensis wurde in Gegenwart und in Abwesenheit von Natrium-dodecylsulfat (SDS) untersucht. Die CD-Banden im 240-bis 320-nm-Bereich des Spektrums wurden durch das Detergens fast vollstandig eliminiert, was auf Zerstorung der Tertiarstruktur der Proteine hinweist, wobei die sterischen Einschrankungen der aromatischen Chromophore entfallen. Im fernen UV dagegen wurden durch SDS Veranderungen hervorgerufen, die auf eine Erhohung des Helixgehaltes hinweisen, wie bereits an vielen anderen Proteinen beobachtet wurde. Es wird vorgeschlagen, diese Art der Denaturierung, in der der Helixgehalt durch das Detergens erhoht wird, als rekonstruktive Denaturierung zu bezeichnen.
|
2022-09-12T14:43:19.019Z
|
213,282,956 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4000/nuevomundo.77800",
"MAG": "2979456235",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://doi.org/10.4000/nuevomundo.77800"
}
|
A presenca de um cachorro bebendo agua aos pes da famosa Mulher Tapuya, tela do pintor holandes Albert Eckhout, tem sido ha tempos associada ao simbolismo do primitivo, do selvagem e do inculto que o artista provavelmente desejou transmitir com a pintura, ao seguir as convencoes pictoricas do seculo XVII. Contudo, a companhia canina desta mulher indigena, se lida em paralelo com algumas outras poucas fontes disponiveis para o mesmo periodo, revela-nos algumas pistas interessantes sobre a veloz difusao do cao (Canis familiaris) entre os povos indigenas na porcao oriental da America do Sul, onde o animal nao existia em tempos pre-colombianos. Alem disso, as imagens e os textos nos permitem especular sobre os momentos iniciais da relacao entre humanos e cachorros nas terras baixas sul-americanas, indo-se, entao, alem da carga alegorica comumente atribuida ao animal.
|
2022-10-14T01:15:01.457Z
|
122,088,429 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1098/rspa.1991.0022",
"MAG": "2147764834",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Everitt’s criterion for the validity of the generalized Hardy-Littlewood inequality presupposes that the associated differential equation is singular at one end-point of the interval of definition and is in the strong-limit-point case at the end-point. In this paper we investigate the cases when the differential equation is in the limit-circle case and non-oscillatory at the singular end-point and when both end-points of the interval are regular.
|
2022-12-19T08:04:16.213Z
|
37,095,117 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1939-1676.1993.TB01010.X",
"MAG": "2024913659",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This article evaluates the responses of 14 dogs with brain masses using orthovoltage irradiation for definitive treatment. Dogs were anesthetized for computed tomography (CT) examination, formation of head immobilization and positioning devices, radiation treatment simulation, and treatments. Total doses of 39 Gy (9 dogs) or 45 Gy (5 dogs) to the tumor were administered over 25 to 41 days. Two or three portals (parallel opposed lateral with or without a dorsal field) were used. Treatment volumes included the tumor and peritumoral edema, as determined by CT scan, and a 1-cm margin. Histopathologic diagnoses were available in 9 of 14 dogs. There were 4 meningiomas, 1 lymphosarcoma, 1 pituitary adenoma, 1 metastatic anaplastic carcinoma, 1 anaplastic oligodendroglioma and 1 dog with granulomatous meningoencephalitis. At the end of radiation therapy, 10 dogs could be evaluated for progression of clinical signs: 3 dogs deteriorated or failed to improve, and 7 dogs improved. At the time of analysis, all dogs were dead. Mean and median survival times, measured from the beginning of radiation, were 345 and 489 days, respectively. This was compared with mean survival times of 30 to 81 days reported in the literature for dogs with brain tumors that did not receive treatment. The median survival time of 9 dogs treated with 39 Gy was 153 days, versus 519 days for 5 dogs that received 45 Gy. It appears that radiation therapy prolongs survival times for dogs with brain masses. Although megavoltage therapy would be optimal, orthovoltage radiation can be applied in total doses of 45 Gy in 3.75 Gy fractions over 28 days without adverse effects.(ABSTRACT TRUNCATED AT 250 WORDS)
|
2022-12-23T02:12:30.017Z
|
234,369,485 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.36108/UJEES/1202.30.0110",
"MAG": "3153793858",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In the early stage of software development, design complexity metrics are considered as useful indicators of a software testing effort and quality attributes. However, existing works made great efforts in establishing standardized metrics to evaluate the complexity of software, but there have not been significant efforts in finding the correlations among the cognitive complexity metrics. To address this challenge, this paper reviewed cognitive complexity metrics which includes: Improved Cognitive Complexity Measure (ICCM), New Cognitive Complexity of Program (NCCoP) and Modified Cognitive Complexity Measure (MCCM). The metrics were employed to analyse some selected sorting algorithms implemented in a procedural C programming language. The relationships among the aforementioned metrics were calculated using the Pearson Correlation Coefficient Method. The results of the comparative examination of ICCM, NCCoP and MCCM revealed that ICCM had more responsive measurements and that there exists a strong relationship among the specified metrics. ICCM had the strongest significance among the considered metrics based on the efforts in comprehending the information contained in the sorting algorithm codes. The study contributed significantly to understanding and addressing the complexity emanating from software development.
|
2022-04-30T12:33:54.975Z
|
19,940,169 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ACC.2007.4282292",
"MAG": "2119693600",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The aim of this work is to study the reliable control design problem for parameter-dependent interconnected systems. A more practical model of actuators or control channels failures than outage is adopted. The continuous Hinfincontrol problem is solved via elementary manipulations on linear matrix inequalities (LMI). Based on LMI design approach, a class of reliable decentralized local state feedback controllers is presented. The resulting control systems are robustly stable against plant uncertainty and failures, and Hinfin performance is ensured.
|
2022-06-21T14:19:03.849Z
|
245,906,974 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/cpp.2711",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Metacognitive beliefs have emerged as important to health anxiety, particularly beliefs that health-related thoughts are uncontrollable. Preliminary research examining generalized worry indicates uncontrollability beliefs relate more strongly to anxiety among U.S.-based self-identifying White relative to Black college students. The present study sought to extend that line of research by examining if metacognitive beliefs about the uncontrollability of health-related thoughts differentially relate to health anxiety among self-identifying non-Latinx Black (n = 123), Latinx (n = 104), and non-Latinx White (n = 80) U.S.-based primary care patients. As predicted, although positive associations were seen across all three groups, beliefs that health-related thoughts are uncontrollable more strongly related to health anxiety among White patients compared to both Black and Latinx patients. Those differential relations held in multivariate analyses while statistically controlling for positive depression screening status, generalized anxiety symptom severity, and medical morbidity. Although the effect size surrounding the differential relations was small in magnitude, the present results further support the notion that metacognitive beliefs about uncontrollability relate less strongly to anxiety among U.S.-based ethnoracial minorities compared to White individuals. Potential reasons for the differential relations are discussed, along with additional areas for future research.
|
2022-06-28T02:09:42.877Z
|
245,315,113 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.35774/sf2021.03.008",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "http://sf.wunu.edu.ua/index.php/wof/article/download/1465/1471"
}
|
Introduction. The established quarantine and social distancing have resulted in falling financial capacity of territorial communities, growing unemployment among the population, mass bankruptcy of enterprises, and changes in economic entities’ behavior. It makes the issue of determining behavioral aspects of making financial decisions and their adjustment to the impact of the coronavirus crisis of utmost importance because the overcoming of the coronavirus crisis by economic entities depends on the adaptation of their vital activity to new conditions.
The purpose of the article is to outline the behavioral aspects of making financial decisions on a local level in conditions of the pandemic.
Methods. The research is based on the use of dialectical analysis, synthesis, analogy, and logical generalization, as well as comparison and formalization.
Results. The research has resulted in substantiation of the expediency of considering the coronavirus crisis in the context of the philosophical idea of black swan and an approach to the analysis of economic entities’ behavior as a reaction to uncertainty. The factors impacting the collective behavior in territorial communities are identified (social norms, social identity, collective memory, system of values, social inequality, economic conditions). The additional factors that determine the collective behavior in conditions of the pandemic are outlined (use of various information sources, discrepancies between forecasts, lack of evidence, high scientific uncertainty, times frame). The mistakes in cognitive processes of economic entities in territorial communities caused by the coronavirus crisis consequences are revealed. The features of making financial decisions in the process of managing the development of territorial communities in conditions of the pandemic are determined.
|
2022-02-07T20:00:29.318Z
|
154,043,951 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3386/W6446",
"MAG": "1894681870",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In The Bell Curve, Herrnstein and Murray argue that the U.S. economy is a meritocracy in which differences in wages (including differences across race and gender) are explained by differences in cognitive ability. In this paper we test their claim for wages conditional on occupation using a simultaneous model of occupation choice and wage determination. Our results contradict Herrnstein and Murray's claim that the U.S. labor market operates only on meritocratic principles.
|
2022-12-13T02:21:49.745Z
|
189,818,432 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/molecules24112131",
"MAG": "2948378460",
"PubMedCentral": "6600596"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/1420-3049/24/11/2131/pdf?version=1559910262"
}
|
Hispidulin (4′,5,7-trihydroxy-6-methoxyflavone) is a natural compound derived from traditional Chinese medicinal herbs, and it is known to have an anti-inflammatory effect. Here, we investigated the effect of hispidulin on the immunoglobulin E (IgE)-mediated allergic responses in rat basophilic leukemia (RBL)-2H3 mast cells. When RBL-2H3 cells were sensitized with anti-dinitrophenyl (anti-DNP) IgE and subsequently stimulated with DNP-human serum albumin (HSA), histamine and β-hexosaminidase were released from the cells by degranulation of activated mast cells. However, pretreatment with hispidulin before the stimulation of DNP-HSA markedly attenuated release of both in anti-DNP IgE-sensitized cells. Furthermore, we investigated whether hispidulin inhibits anti-DNP IgE and DNP-HSA-induced passive cutaneous anaphylaxis (PCA), as an animal model for Type I allergies. Hispidulin markedly decreased the PCA reaction and allergic edema of ears in mice. In addition, activated RBL-2H3 cells induced the expression of inflammatory cytokines (tumor necrosis factor-α and interleukin-4), which are critical for the pathogenesis of allergic disease, through the activation of c-Jun N-terminal kinase (JNK). Inhibition of JNK activation by hispidulin treatment reduced the induction of cytokine expression in the activated mast cells. Our results indicate that hispidulin might be a possible therapeutic candidate for allergic inflammatory diseases through the suppression of degranulation and inflammatory cytokines expression.
|
2022-12-14T23:07:43.202Z
|
42,698,268 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1364/OPEX.12.001864",
"MAG": "2038257976",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We propose a simple geometric criterion based on the size of the core relative to the photonic crystal to quickly determine whether an air-core photonic-bandgap fiber with a given geometry supports surface modes. Comparison to computer simulations show that when applied to fibers with a triangular-pattern cladding and a circular air core, this criterion accurately predicts the existence of a finite number of discrete ranges of core radii that support no surface modes. This valuable tool obviates the need for time-consuming and costly simulations, and it can be easily applied to fibers with an arbitrary photonic-crystal structure and core profile.
|
2022-12-16T12:18:29.672Z
|
31,456,427 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.15376/BIORES.8.4.5202-5218",
"MAG": "1996942105",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Birch sawdust was extracted with a pressurized hot water (PHW) flow-through system. The pH of the extract was controlled during extraction by the addition of acetic acid/sodium acetate buffer. Three different pH levels, 4.0, 4.2, and 4.6, were used. Extraction temperatures were 160, 170, and 180 °C, with a constant 4 mL/min flow rate through the 50 mL extraction vessel. During PHW extraction with plain water, the end pH of the extract dropped from 5 to below 3. Buffers kept the pH of the extracts constant during the first 30 min of extraction. Compared to plain water, the use of buffers resulted in a lower yield of xylans during the 170 °C extraction. However, with the buffered system it was possible to obtain xylans from sawdust with a higher molar mass than plain water extraction. Acetic acid/sodium acetate buffer enabled control of the hydrolysis rate of xylans during extraction.
|
2022-12-30T01:05:12.027Z
|
94,614,267 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1063/1.1416902",
"MAG": "2623506435",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
This review contains selected values of thermodynamic quantities for the aqueous ionization reactions of 64 buffers, many of which are used in biological research. Since the aim is to be able to predict values of the ionization constant at temperatures not too far from ambient, the thermodynamic quantities which are tabulated are the pK, standard molar Gibbs energy ΔrG∘, standard molar enthalpy ΔrH°, and standard molar heat capacity change ΔrCp∘ for each of the ionization reactions at the temperature T=298.15 K and the pressure p=0.1 MPa. The standard state is the hypothetical ideal solution of unit molality. The chemical name(s) and CAS registry number, structure, empirical formula, and molecular weight are given for each buffer considered herein. The selection of the values of the thermodynamic quantities for each buffer is discussed.
|
2022-12-30T16:03:09.007Z
|
231,156,697 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3760/CMA.J.ISSN.1008-6706.2013.14.022",
"MAG": "3031784026",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Objective To investigate the clinical effect and safety of microwave thermosetting joint pingyangmycin injected within the occlusion in treatment of maxillofacial hemangioma.Methods The clinical data of 102 patients with maxillofacial hemangioma were retrospectively analyzed.According to the different period of the different choice of treatment,the patients were divided into microwave thermosetting group and surgery group.The clinical effect,treatment time and hairdressing effect of the two groups were analyzed.Results Total effective rate of microwave thermosetting group was 96.30％,surgery group was 95.83％,the difference between the two groups had no statistical significance (x2 =0.153,P ＞ 0.05).The average surgical time of surgery group was obviously shorter than microwave thermosetting group(t =7.625,P ＜ 0.01),but satisfaction of hairdressing effect in microwave thermosetting group was obviously higher than that of the surgery group(90.74％ vs 75.00％,x2 =4.533,P ＜0.05),the incidence rate of adverse reaction was significantly lower than the surgery group(5.56％ vs 18.75％,x2 =4.262,P ＜ 0.05).The facial nerve injury occurred in 3 patients (6.2 5 ％) after operation in the surgery group,microwave thermosetting group had no facial nerve injury after treatment.There was no recurrence after follow-up for 6 months.Conclusion The clinical effect and hairdressing effect of microwave thermosetting joint pingyangmycin injected within the occlusion in treatment of maxillofacial hemangioma are satisfied,the incidence rate of adverse reaction and complication is relatively low.It is safe and effective,which is worth expanding in clinical practice.
Key words:
Hemangioma; Face; Microwave; Pingyangmycin
|
2022-01-27T02:05:49.954Z
|
211,684,629 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICHVEPS47643.2019.9011140",
"MAG": "3009094733",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Power transformer is the heart of power system and critical equipment in transmission line grid. Reliability of power transformer is the most important thing in transmission system. UIT JBT (Unit Induk Transmisi Jawa Bagian Tengah) as a unit of PLN that operates and maintains the middle section of java transmission system is responsible for ensuring power system reliability. Dissolved Gas Analysis (DGA) is widely used for interpreting condition and faults diagnostic of power transformer that depend on concentrations and composition of gases in transformer’s oils. It can be used to identify the type of pending or occurring faults and estimate it’s severity that will be used to determine the appropriate action and avoid unexpected failure. Transformer 150/20 kV 60 MVA at Tambun Substation has special case, which has only been operating since 2012 but in 5 years of operation detected anomaly (infant failure). Diagnosis of defects is obtained by DGA test and the interpretation indicated thermal fault 700°C. DGA trend showed a significant increase in gas concentration was detected which was suspected due to an internal fault of the transformer. The transformer followed up with shutdown investigation, and insulation test measurement between core and frame of the transformer indicated a short circuit which is further detected as a result of the displacement of the magnetic shunt that slide and shorting the core and the frame. Further corrective action taken by on site repair.
|
2022-02-08T03:08:52.792Z
|
109,657,591 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4028/www.scientific.net/AMR.716.693",
"MAG": "1976660554",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
About under-group coal seams mining with the threat of high-pressure ordovician water, conventional mining technology by draining depressurization usually causes environmental issues such as soil erosion and ground subsidence etc.,By using grouting reinforcement technology, this paper changes floor direct charge layer into relatively separatedwater layer in the coal seam and achieves the goals of sealing the water inrush channel, moreover, on the basis of coal floor failure depth analysis and monitoring, the paper evaluates risk of water-inrush from seam floor when face length increases, On this basis, puts forward a reasonable working face length and mining technology, and has abtained good economic and social benefits in practice.
|
2022-02-10T05:47:08.692Z
|
140,703,969 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/02571862.1996.10634385",
"MAG": "1990576505",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://www.tandfonline.com/doi/pdf/10.1080/02571862.1996.10634385?needAccess=true"
}
|
A commercially available salinity sensor (model EM-38 of Geonics Ltd., Canada) has been developed for diagnosing and quantifying soil salinity in the field. There is a need, however, to calibrate the instrument reading against a more commonly used measure of soil salinity. Linear regression equations are reported that allow the interpretation of field instrument readings in terms of electrical conductivity of the saturation extract (ECe) measured in the laboratory. Instrument measurements and soil samples were taken at some 110 sites on various irrigation schemes distributed across South Africa. Samples were analysed in the laboratory and soils categorized according to texture, water status and salinity distribution with depth. Calibration equations were developed firstly by relating field instrument readings, taken either in the vertical or horizontal position, to a depth-integrated ECe value which was weighted for depth according to instrument response. Secondly, the mean of the readings taken in the ve...
|
2022-09-10T11:42:55.100Z
|
231,855,302 |
{
"externalids": {
"ACL": null,
"ArXiv": "2102.04621",
"DOI": "10.1109/ISCAS51556.2021.9401218",
"MAG": "3158409426",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Gait, i.e., the movement pattern of human limbs during locomotion, is a promising biometrie for identification of persons. Despite significant improvement in gait recognition with deep learning, existing studies still neglect a more practical but challenging scenario — unsupervised cross-domain gait recognition which aims to learn a model on a labeled dataset then adapt it to an unlabeled dataset. Due to the domain shift and class gap, directly applying a model trained on one source dataset to other target datasets usually obtains very poor results. Therefore, this paper proposes a Transferable Neighborhood Discovery (TraND) framework to bridge the domain gap for unsupervised cross-domain gait recognition. To learn effective prior knowledge for gait representation, we first adopt a backbone network pre- trained on the labeled source data in a supervised manner. Then we design an end-to-end trainable approach to automatically discover the confident neighborhoods of unlabeled samples in the latent space. During training, the class consistency indicator is adopted to select confident neighborhoods of samples based on their entropy measurements. Moreover, we explore a high- entropy-first neighbor selection strategy, which can effectively transfer prior knowledge to the target domain. Our method achieves the state-of-the-art results on two public datasets, i.e., CASIA-B and OU-LP.
|
2022-11-22T13:27:13.953Z
|
254,908,098 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.37399/issn2072-909x.2022.si.32-45",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The article deals with the provisions of changing the norms of the Civil Code of the Russian Federation in part of new objects of civil rights: investment tokens for shares, digital rights for information technology, derivative financial instruments or their equivalents, obligations. Stochastic smart-obligations as the special part of fiduciary obligation, the issues of liability regarding digital financial assets, digital rights, as new objects of civil rights on the basis of the contract are touched upon, the effectiveness of the application of the model of legal regulation of legal obligations. The author analyzes the new norms of the Federal Law No. 34, as well as legislation in general and practice in terms of determining the legal status of participants in contractual relations. This article introduces especially corporate area and will discuss the implementation of rights on derivatives involving a contract with a forex dealer. It will also consider the possibility of applying the institutions of the refusal to execute the contract, the waiver on such contracts and some other legal relations involving the exercise of rights using technical and electronic means. Additionally, the provisions of the Federal Law No. 259 ‘On digital financial assets’ was analyzed.
|
2022-12-21T17:52:53.170Z
|
2,796,816 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3217/jucs-011-09-1568",
"MAG": "2113623622",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Authoring learning material is a multi-disciplinary undertaking where different people can play their role. Any support that can be provided for the collaboration of instructional designers, pedagogues, media designers, and students, among others, is welcome. In particular, metadata annotation of learning objects is an important task within the whole authoring process. This work presents the first resulting products and approaches from the MD2 project, consisting of a service-oriented framework and a tool to support the integrated, ontology-based collaborative annotation of learning objects.
|
2022-12-21T10:29:33.442Z
|
149,743,267 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3928/24748307-20181113-01",
"MAG": "2908690127",
"PubMedCentral": "6608912"
},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://doi.org/10.3928/24748307-20181113-01"
}
|
Background: Health literacy and socioeconomic status (SES) are associated with both race/ethnicity and asthma outcomes. The extent to which health literacy and SES mediate racial/ethnic asthma disparities is less clear. Objective: To determine if health literacy and SES mediate racial/ethnic asthma disparities using advanced mediation analyses. Methods: A secondary analysis was performed using a Chicago-based longitudinal cohort study conducted from 2004 to 2007 involving 342 adults age 18 to 41 years with persistent asthma. Phone interviews were conducted every 3 months assessing asthma quality of life (AQOL; scored 1–7, with 7 being the highest) and asthma-related health care use measures. Structural equation models assessed mediation of race/ethnicity effects on AQOL and health care use through health literacy and SES. Covariates in the best-fit model included sex, year and season of interview, and cigarette smoking. Key Results: The study sample was 77.8% female, 57.3% African American/non-Hispanic, and 28.7% Hispanic. Race/ethnicity was significantly associated with AQOL and asthma-related emergency department (ED) visits, but only indirectly, through the effects of health literacy and income. Compared with White/non-Hispanics, African American/non-Hispanics and Hispanics had significantly higher odds of low health literacy and lower income. Low health literacy was associated with significantly lower AQOL scores (β = −0.24, 95% confidence interval (CI) [−0.38, −0.10]) and higher odds of an ED visit (adjusted odds ratio = 1.24, 95% CI [1.07, 1.43]). Increasing income was associated with significantly higher AQOL scores (β = 0.18, 95% CI [0.08, 0.28]) and lower odds of an ED visit (adjusted odds ratio = 0.88, 95% CI [0.80, 0.97]). Conclusions: The relationships between race/ethnicity and several asthma outcomes were mediated by health literacy and income. Interventions to improve racial/ethnic asthma disparities should target health literacy and income barriers. [HLRP: Health Literacy Research and Practice. 2019;3(1):e9–e18.] Plain Language Summary: Using advanced statistical methods, this study suggests racial/ethnic differences in several asthma outcomes are largely due to effects of health literacy and income. Interventions to improve racial/ethnic asthma disparities should target health literacy and income barriers.
|
2022-08-24T02:51:53.036Z
|
8,375,677 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1136/BMJ.288.6429.1473",
"MAG": "2046655140",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
"Why let the burdens of old age get on top of you . .. live in complete luxury . . . [we] enable you to enjoy your well earned retirement . . . offer life's much sought after pleasures and allow you to relax in comfort while expert staff attend to your every wish . . . if your capital is £3000 or less the DHSS will fund the average fee." Not Saga Holidays offering winter breaks in Spain, or even soft words from the Minister of Health to octogenarian general practitioners, but excerpts from a feature in a local paper' by the Hampshire Registered Rest Homes Association, entrepreneurs helping the govern-
|
2022-09-06T10:12:45.142Z
|
220,679,396 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/0146107913493565",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Every society has an organizational structure that reflects what is valued by that society. Those members of the society that are deemed more valuable or that contribute more to society are rewarded with a larger share of the goods and services. The ancient Mediterranean world functioned within a rigid hierarchical structure, in which the most valued members were openly designated—in the family, the city, the empire, and the cosmos. The virtues of the social stratification system were made apparent through the patronage/clientage system as the means of distribution of goods, the cultural battle for honor and the aversion to shame, and the patriarchal structure of the family, to name a few instances. Recognition of the prevailing hierarchical structure in the ancient Mediterranean world sheds light upon biblical writings, some of which affirm, and others of which challenge the cultural customs arising from the hyper-stratification of the societies from which they emerged.
|
2022-09-13T11:09:42.475Z
|
24,033,641 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1460-9568.1995.tb01021.x",
"MAG": "2149848104",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In the CNS of the snail Lymnaea stagnalis, Phe‐Met‐Arg‐Phe‐amide (FMRFamide)‐like and additional novel neuropeptides are encoded by a common, multi‐exon gene. This complex locus, comprising at least five exons, is subject to post‐transcriptional regulation at the level of alternative RNA splicing. Our aim was first to analyse the pattern by which exons of this neuropeptide locus combine during splicing of the primary RNA transcript, and second to investigate the functional significance of splicing by mapping the expression and neuronal localization in the CNS of the alternative mRNA transcripts, in the context of defined neuronal networks and single identified neurons. The approach was a combination of comparative in situ hybridization and immunocytochemistry, using a battery of exon‐specific oligonucleotides and anti‐peptide antisera. The analysis illustrated that exons III, IV and V were always coexpressed and colocalized whereas the expression of exon II was always differential and mutually exclusive. Both sets of exons were, however, coexpressed with exon I: the total number of exon I‐expressing neurons was equal to the combined number of neurons expressing exon III/IVA/ and neurons expressing exon II. In addition, it was revealed that the extreme 5’of exon II, encoding a potential hydrophobic leader signal, was not expressed in the CNS of Lymnaea but was apparently spliced out during RNA processing. Both mRNA transcripts of the FMRFamide locus, type I (exons I/II) and type 2 (exons I/III/IV/V), were translated in the CNS and the resulting protein precursors were also expressed in a mutually exclusive fashion, as were their respective transcripts. The expression of alternative transcripts within identified networks or neuronal clusters was heterogeneous, as exemplified by the cardiorespiratory network. On the basis of this work and a previous cDNA analysis, we put forward a revised model of differential splicing and expression of the FMRFamide gene in the CNS of Lymnaea.
|
2022-12-13T01:59:39.617Z
|
169,888,070 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/16522354.2018.1481711",
"MAG": "2805600235",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
ABSTRACTThe streaming platform Netflix began to offer on-demand content in Spain in 2015. This study offers an analysis of the Twitter strategy the company implemented during its initial year in this market. We conclude that the Twitter strategy employed by Netflix during this period differed substantially from those pursued by traditional television. Netflix makes extensive use of original messages and social media conventions such as hashtags, emoticons and gifs. Analysis indicates that the brand’s Twitter followers in Spain are more likely to like and retweet messages than post replies.
|
2022-12-29T17:38:50.814Z
|
84,170,165 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1365-2745.2007.01254.x",
"MAG": "1995033847",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://besjournals.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-2745.2007.01254.x"
}
|
1 Seed banks are important to many plant populations, yet we lack clear understanding of how environmental factors promote seed bank formation. We experimentally varied seed density, and soil disturbance size and timing, to examine the formation of seed banks and the resulting population dynamics in wild annual sunflowers (Helianthus annuus). Seed density treatments reflected the expected increase in seed production of individual wild sunflowers due to hybridization with Bt‐transgenic crop sunflowers. Soil disturbances of two sizes (large and small) were applied either before or after seed dispersal. We followed the experimental plots for 21/2 years measuring seedling emergence, seeds in the soil, and reproduction, while preventing additional seed input. We assessed seed bank formation by the numbers of emergent seedlings and seeds in the soil. 2 Soil disturbances, regardless of timing, were required for successful germination and reproduction of wild sunflowers. Large disturbances resulted in greater seedling emergence and reproduction than small disturbances. Reproduction on small disturbance plots was low, due to low seedling survival. Higher seed density resulted in more seedlings only in large‐disturbance plots. 3 Post‐dispersal disturbances led to significant seed bank formation. This effect was greater for large, post‐dispersal disturbances. Higher seed density increased seed bank size only in the presence of large, post‐dispersal disturbances. 4 Negative density‐dependence in seedling mortality and reproduction meant that there was no effect of the high seed density treatment on reproduction. Thus the positive effects of increased seed bank size on population growth were tempered by density‐dependence. To assess fully the impact of seed banks on population growth, studies should continue beyond the seedling stage. 5 Our results suggest increased seed production of individual sunflowers resulting from crop transgenes would be unlikely to increase population growth on the scale of small patches. Increased seed production could result in dispersal of seeds across larger areas, and thus could lead to larger seed banks in disturbed environments and an increased prevalence of sunflowers across the landscape. These results are relevant to other annual species, especially those with transgenic crop relatives.
|
2023-01-01T18:14:41.979Z
|
203,321,602 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.24014/sb.v16i1.6960",
"MAG": "2970487870",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "http://ejournal.uin-suska.ac.id/index.php/SosialBudaya/article/download/6960/4209"
}
|
Culture and society are one unity that cannot be separated from each other, therefore with the existence of various ethnic groups, various traditions are born. In addition, culture can be seen as values that are believed to be shared in a society and can be internalized in individuals so that they live in every behavior, one of which is in the marriage customs of each tribe that has unique and very interesting differences and we must know and preserve, because Indonesia is very rich in culture that we must guard together, by knowing the difference does not mean we insult and blame instead guard and respect each other. The purpose of this study was to determine the differences and similarities of the marriage customs of the Banjar and Bugis tribes. The method that I use is a qualitative method. Type of library research (library reseach), the approach used is an ethnographic approach by examining cultural phenomena that exist in society. The results of this study are the marriage customs of the Banjar and Bugis tribes that have differences and similarities. The first difference is about the term money given to women from the male side by the term uag jujuran (Banjar tribe) and panai money (Bugis tribe), while the equation is something that must be fulfilled in the custom of marriage and the same form money. The next difference is about the factors that influence the high and low amount of money given, then in practice it also has similar differences and similarities, only procedurally different.
|
2022-02-08T04:38:01.531Z
|
197,813,131 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.25273/CITIZENSHIP.V7I1.4294",
"MAG": "2950407503",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This study aims to see the relevance of Pancasila values as a defense paradigm in Indonesia in dealing with modern threats. This research uses doctrinal methods with statue approach. The pancasila values able to unite, collaborate with all the elements in order to achieve and realize the goals of the State of Indonesia. Pancasila values still need to be held firmly and realized in the all aspects of the Indonesian people’s life. Pancasila is a defense paradigm that has been tested in the Indonesian people struggle history in facing threats from within and outside the country. Pancasila as a defense paradigm is still very relevant to be used to deal with various forms of threats both conventional threats and modern threats as we are currently facing.
|
2022-02-08T06:26:21.109Z
|
210,931,773 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CISP-BMEI48845.2019.8965676",
"MAG": "3002836794",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Current neurosurgery registration methods can be divided into two categories: marker-based and markerless. Maker-based methods need fiducials on patients' heads, which may cause additional harm to them. Traditional markerless registration methods always require interaction, expensive equipment and specific posture of patients. In this paper, we explore how deep neutral network can be used in neurosurgery registration problem. And the method of this paper mainly includes three parts: 3D reconstruction and face mesh model feature point extraction, binocular face feature point cloud generation, point cloud registration. To this end, we make the following contributions: (a) we propose an automatic registration pipeline based on heat maps generated from Convolutional Neural Network (CNN), which is totally dependent on the anatomic facial feature points of patients and free of extra fiducials. (b) we use comparatively cheap binocular cameras instead of surface scanner to collect patients' facial information. (c) we don't use 3D CNNs to extract facial feature points of the medical images like CT, instead we use 2D CNNs on the projection images and get 3D facial feature points from their corresponding 2D facial feature points. As a result, it can relieve the lack of 3D training data and save the run-time memory. We show that the registration precision is dominant to the accuracy of facial key point extraction, and the network we use exhibits powerful performance.
|
2022-06-14T22:41:57.915Z
|
23,291,725 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1103/PHYSREVB.44.2306",
"MAG": "2021808098",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
X-ray and ultraviolet photoelectron-spectroscopic (XPS and UPS) studies to investigate the core levels and valence-band spectra of ${\mathrm{BaV}}_{1\mathrm{\ensuremath{-}}\mathit{x}}$${\mathrm{Ti}}_{\mathit{x}}$${\mathrm{S}}_{3}$, with x=0 and 0.2, is reported. The XPS results indicate that the valence of V as well as Ti is not 4 as would be expected nominally, but between 3 and 4. Essentially no difference of the core-level binding energies was observed between the two samples. The valence-band spectra exhibit three peak features at about 1, 2.5, and 4 eV. From the enhancement of the peak at 1 eV by the He ii photon, it is concluded that the V 3d orbitals are strongly incorporated in this peak that is close to the Fermi level. It is shown that the bond-valence-sum method can be useful as a quantitative tool for discussion of XPS results. The possibility of using the bond-valence-sum calculation for discussions on the transport properties of the system is also shown.
|
2022-09-07T18:26:25.301Z
|
234,388,932 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.15406/UNOAJ.2020.08.00298",
"MAG": "3146396403",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Objective: To evaluate the effect of warm ischemic time (WIT) on future renal function (RF) after robotic partial nephrectomy (RPN) and secondarily, also to find out predictors of future RF after RPN. Method and materials: All patients who underwent RPN with normal pre-operative RF and normal contralateral kidney were included in the study except for those in whom one-year follow up was not completed. Patients were divided in four groups based on WIT (zero, <20minutes, 20 minutes to 30 minutes and >30 minutes). Comparison of demographic and perioperative parameters including follow-up up to one year were done. Univariable and multivariable analysis were done to detect significant correlation of RF with those parameters. Results: Total 198 RPN patients were included in the study. The four groups had comparable demographic data (age, gender, comorbidity, smoking, body mass index, pre-operative RF). Progressively increased WIT was significantly associated with increased tumour size (p=0.022), RENAL nephrometry score (p=0.003), operative time (p=0.004) and blood loss (p=0.046). Post-operatively, RF on first post-operative day (p=0.627), at one month (p=0.581) and at one year (p=0.378) had no significant difference between the four groups. Nine (4.5%) patients progressed to chronic renal disease. Pre-operative RF and perioperative complications only had significant correlation with one-year RF. Conclusion: Tumour size and RENAL nephrometry score significantly influenced WIT. Pre-operative RF and peri-operative complications were the only significant predictors of future RF and not the WIT.
|
2022-06-25T22:55:00.516Z
|
23,886,433 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/jssc.201000040",
"MAG": "2021263138",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In the present study the migration order of the propranolol enantiomers with various native CDs and neutral and charged CD derivatives was examined in capillary electrophoresis (CE). The reversal of the enantiomer migration order was observed due to sulfation of beta-CD on its primary hydroxy groups. The structures of intermolecular selector-select and temporary diastereomeric associates in solution were elucidated based on 1D rotating frame nuclear Overhauser effect spectroscopy (1D ROESY) experiments. Major structural differences were observed between the propranolol complexes with native beta-CD and heptakis(6-O-sulfo)-beta-CD.
|
2022-12-12T23:28:43.370Z
|
1,261,448 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/03635465030310051201",
"MAG": "2118586445",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
Background Graft-tunnel mismatch is a potential problem during single-incision technique for anterior cruciate ligament reconstruction with the central third of the patellar tendon. Mismatch is present when the graft is too long to fit appropriately in the tunnels that have been created. Graft rotation is one method for addressing this problem. Purpose To determine the results of graft rotation up to 540° on initial graft biomechanical properties and graft length. Study Design Controlled laboratory study. Methods Forty porcine bone-patellar tendon-bone constructs were divided into four groups and constructs were rotated to 0°, 90°, 180°, and 540°, respectively, for each group. Biomechanical testing to failure was performed with the constructs under tension at an elongation rate of 5 cm/sec. Lengths were measured after a 1-kg load was applied to the grafts. Results No statistical difference in ultimate failure strength was encountered between any of the groups (P = 0.915). The grafts that were twisted to 540° shortened an average of 5.41 mm, which represented an average shortening of 10% of the initial tendon length. Clinical Relevance Graft rotation up to 540° does not result in loss of initial graft strength, and may be a solution for graft-tunnel mismatch.
|
2022-12-17T15:14:32.295Z
|
56,395,754 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5713/AJAS.2004.366",
"MAG": "2105566517",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
One hundred and sixty day-old Hainan chicks were randomly allotted into eight pens to investigate the effect of different dietary concentrations of chromium (Cr) in the form of chromium chloride, and different dosages of florfenicol on humoral immune responses by determining antibody titers to Newcastle disease (ND) vaccines using the hemagglutination inhibition test. The results indicated that ND antibody titers were significantly higher in chicks receiving Cr at low (5 mg/kg feed) and middle (10 mg/kg feed) dose compared with the control (p 0.05), but the ND antibody titers were significantly decreased in chicks receiving 200 and 400 mg/kg feed of the drug (p<0.01). The ND antibody titers of group receiving 200 mg/kg feed of florfenicol plus 10 mg/kg Cr were slightly higher than that of the group receiving single florfenicol of 200 mg/kg although, no significant differences were observed between these two treatments. It is suggested that the humoral immune response impaired by florfenicol (200 mg/kg feed) could not be significantly reversed by Cr (10 mg/kg feed). (Asian-Aust. J. Anim. Sci. 2004. Vol 17, No. 3 : 366-370)
|
2022-12-26T20:33:38.218Z
|