corpusid
int64 5
255M
| openaccessinfo
dict | abstract
stringlengths 1
10k
| updated
stringlengths 20
24
|
|---|---|---|---|
252,832,997 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.55529/ijitc.22.22.33",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "http://journal.hmjournals.com/index.php/IJITC/article/download/1038/1192/1477"
}
|
Teaching and Learning activities in gotong royong junior high schools are currently conventional only limited to meetings in schools. The time available for teachers and students to meet face to face in the classroom is very limited, in addition, the process of delivering the material is almost completely carried out in the classroom which causes the delivery of the material to be late, when a student does not enter school, the student will later find it difficult to follow the learning process. therefore, a Mobile Web-Based Learning Application was created at Gotong Royong Junior High School, using the Prototype model system development method, the results of this research are a mobile webbased learning application, it can be concluded that the learning application has been designed and implemented with facilities including downloading materials, assignments or online quiz and student scores.
|
2022-10-14T00:41:47.229Z
|
93,450,972 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1039/P29910001773",
"MAG": "1965207195",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The kinetics of the nitrous acid catalysed nitration of naphthalene in aqueous trifluoroacetic acid and in mixtures of methanesulphonic acid and acetic acid involve a term that is second-order with respect to the aromatic substrate. The second-order term becomes predominant when the concentration of naphthalene exceeds 0.01 mol dm–3. This term is absent in the corresponding reaction of 1,5-dimethylnaphthalene. The difference between the kinetic forms of the two reactions is attributed to the known difference in the ease of formation of the dimer radical cations {(ArH)2˙+} from the two aromatic compounds. The difference in the kinetic forms also implies that the relative reactivity of these substrates in nitrous acid catalysed nitration must depend on the initial concentrations.
|
2022-03-04T07:55:06.570Z
|
239,051,757 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.12047/j.cjap.0083.2021.113",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Objective: To observe the effect of healthy volunteers different work rate increasing rate cardiopulmonary exercise test (CPET) on the peak exercise core indicators and the changes of respiratory exchange rate (RER) during exercise, to explore the effect of different work rate increasing rate on CPET peak exercise related indicators. Methods: Twelve healthy volunteers were randomly assigned to a moderate (30 W/min), a relatively low (10 W/min) and relatively high (60 W/min) three different work rate increasing rate CPET on different working days in a week. The main peak exercise core indicators of CPET data: VO2, VCO2, work rate (WR), breathe frequency(Bf), tidal volume (VT), ventilation (VE), heart rate (HR), blood pressure (BP), Oxygen pulse(O2P), exercise time and RER for each period of CPET were analyzed using standard methods. The ANOVA test and paired two-two comparison was performed on the difference of each index in the three groups of different work rate increasing rate. Results: Compared with the moderate work rate group, the peak work rate of the lower and higher work rate groups were relatively lower and higher, respectively ((162.04±41.59) W/min vs (132.92±34.55) W/min vs (197.42±46.14) W/min, P<0.01); exercise time was significantly prolonged and shortened ((5.69 ± 1.33) min vs (13.49 ± 3.43) min vs (3.56 ± 0.76) min, P<0.01); peak RER (1.27 ± 0.07 vs 1.18 ± 0.06 vs 1.33 ± 0.08, P<0.01~P<0.05) and the recovery RER maximum (1.72±0.16 vs 1.61±0.11 vs 1.81±0.14, P<0.01~P<0.05) were significantly decreased and increased. Conclusion: Different work rate increasing rate of CPET significantly change the Peak Work Rate, exercise time, Peak RER, and maximum RER during recovery. The CPET operator should choose an individualized work rate increasing rate that is appropriate for the subject, and also does not use a fixed RER value as a basis for ensuring safety, the subject's extreme exercise, and early termination of exercise.
|
2022-01-27T15:55:16.183Z
|
119,617,476 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1063/1.3596565",
"MAG": "1974807419",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "GREEN",
"url": "https://tsukuba.repo.nii.ac.jp/record/24818/files/JAP_109-12.pdf"
}
|
We have epitaxially grown undoped β-FeSi2 films on Si(111) substrates via atomic-hydrogen-assisted molecular-beam epitaxy. β-FeSi2 films grown without atomic hydrogen exhibited p-type conduction with a hole density of over 1019 cm−3 at room temperature (RT). In contrast, those prepared with atomic hydrogen showed n-type conduction and had a residual electron density that was more than two orders of magnitude lower than the hole density of films grown without atomic hydrogen (of the order of 1016 cm−3 at RT). The minority-carrier diffusion length was estimated to be approximately 16 μm using an electron-beam-induced current technique; this value is twice as large as that for β-FeSi2 prepared without atomic hydrogen. This result could be well explained in terms of the minority-carrier lifetimes measured by a microwave photoconductance decay technique. The 1/e decay time using a 904 nm laser pulse was approximately 17 μs, which is much longer than that for β-FeSi2 prepared without atomic hydrogen (3 μs). The...
|
2022-09-22T22:53:33.438Z
|
211,828,929 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3389/fimmu.2020.00364",
"MAG": "3009837239",
"PubMedCentral": "7064638"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.frontiersin.org/articles/10.3389/fimmu.2020.00364/pdf"
}
|
The tumor immune contexture plays a major role for the clinical outcome of patients. High densities of CD45RO+ T helper 1 cells and CD8+ T cells are associated with improved survival of patients with various cancer entities. In contrast, a higher frequency of tumor-infiltrating M2 macrophages is correlated with poor prognosis. Recent studies provide evidence that the tumor immune architecture also essentially contributes to the clinical efficacy of immune checkpoint inhibitor (CPI) therapy in patients. Pretreatment melanoma samples from patients who experienced a clinical response to anti-programmed cell death protein 1 (PD-1) treatment show higher densities of infiltrating CD8+ T cells compared to samples from patients that progressed during therapy. Anti-PD-1 therapy results in an increased density of tumor-infiltrating T lymphocytes in treatment responders. In addition, elevated frequencies of melanoma-infiltrating TCF7+CD8+ T cells are correlated with beneficial clinical outcome of anti-PD-1-treated patients. In contrast, a high density of tumor-infiltrating, dysfunctional PD-1+CD38hi CD8+ cells in melanoma patients is associated with anti-PD-1 resistance. Such findings indicate that comprehensive tumor immune contexture profiling prior to and during CPI therapy may lead to the identification of underlying mechanisms for treatment response or resistance, and the design of improved immunotherapeutic strategies. Here, we focus on studies exploring the impact of intratumoral T and B cells at baseline on the clinical outcome of CPI-treated cancer patients. In addition, recent findings demonstrating the influence of CPIs on tumor-infiltrating lymphocytes are summarized.
|
2022-12-17T21:21:35.849Z
|
235,565,093 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/19386362.2021.1921435",
"MAG": "3158822846",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
ABSTRACT Shallow foundations are seldom rested on the ground surface and are often embedded below the surface. The undrained bearing capacity of embedded footings and the depth factors associated with it for circular and strip foundations were extensively studied in the past. However, the effect of embedment on the undrained bearing capacity of ring foundations has not received much attention. In this paper, the results of numerical analysis to study the effect of embedment of ring foundations resting on cohesive soil are presented. The influence of variation in the geometry of the ring foundation, the footing side roughness coefficients, and the increasing shear strength of cohesive soil has also been studied. The results show a variation in the depth factors by varying the inner and outer diameter of the ring foundation, footing side roughness coefficient, embedment depth, and increasing shear strength of the soil. Based on the results of the analysis, the authors have proposed an equation to evaluate the depth factors for embedded ring foundations in cohesive soil. The failure pattern of subsoil has also been presented and discussed. The depth factors obtained from this study can be used by practicing engineers to evaluate the bearing capacity of onshore and offshore ring foundations in cohesive soils.
|
2022-12-30T18:13:37.970Z
|
41,283,698 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/jor.22042",
"MAG": "2031155048",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc3307871?pdf=render"
}
|
Fracture healing is highly sensitive to mechanical conditions; however, the effects of mechanical loading on large bone defect regeneration have not been evaluated. In this study, we investigated the effects of functional loading on repair of critically sized segmental bone defects. About 6‐mm defects were created in rat femora, and each defect received 5 µg recombinant human bone morphogenetic protein‐2 (rhBMP‐2), delivered in alginate hydrogel. Limbs were stabilized by either stiff fixation plates for the duration of the study or compliant plates that allowed transfer of compressive ambulatory loads beginning at week 4. Healing was assessed by digital radiography, microcomputed tomography, mechanical testing, histology, and finite element modeling. Loading significantly increased regenerate bone volume and average polar moment of inertia. The response to loading was location‐dependent with the polar moment of inertia increased at the proximal end of the defect but not the distal end. As a result, torsional stiffness was 58% higher in the compliant plate group, but failure torque was not altered. In single samples assessed for histology from each group, a qualitatively greater amount of cartilage and a lesser degree of remodeling to lamellar bone occurred in the loaded group compared to the stiff plate group. Finally, principal strain histograms, calculated by FE modeling, revealed that the compliant plate samples had adapted to more efficiently distribute loads in the defects. Together, these data demonstrate that functional transfer of axial loads alters BMP‐induced large bone defect repair by increasing the amount and distribution of bone formed within the defect. © 2011 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 30:1067–1075, 2012
|
2023-01-01T16:28:28.823Z
|
213,691,425 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4314/ft.v8i3.3",
"MAG": "3006495001",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In his [Africans are not Black: The Case for Conceptual Liberation], Kwesi Tsri relies extensively on myths and non-fictional narratives to dictate the origin of the racial disparagement of Afro-Americans and Africans from south of the Sahara. Owing to the synonymy between ‘black’ and ‘Africa(n)’ as well as the derogatory symbolism in the former that fuels the latter, Tsri submits the need to disassociate Africans from the concept, ‘black.’ Upon a critical conversation with Tsri’s text however, Chimakonam discerns three flaws. Granted, the objections are salient, I augment herein, one of Chimakonam’s critiques – the exclusion by Tsri, of nonfictional or scientific texts on the race discourse. Whereas I agree with Chimakonam that both the fictional and non-fictional accounts on race are pertinent for intellectual balance in Tsri’s disquisition, I further suggest that in most cases, non-fictional or scientific theories on race are undergirded by the prejudice initiated by mythical and/or fictional narratives. I substantiate my thesis, relying on Karl Popper’s evolutionary epistemology, with 21st century science admission that human genetic diversity cannot be captured by scientific theories of race.Keywords: Africa, Blackness, Jonathan Chimakonam, Karl Popper, Kwesi Tsri
|
2022-01-27T12:56:34.790Z
|
191,272,059 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.7146/SE.V2I1.5184",
"MAG": "1622978639",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Commercials offer the opportunity for intergenerational memory and impinge on cultural memory. TV commercials for foodstuffs often make reference to past times as a way of authenticating products. This is frequently achieved using visual cues, but in this paper I would like to demonstrate how such references to the past and ‘the good old days’ can be achieved through sounds. In particular, I will look at commercials for Danish non-dairy spreads, especially for OMA margarine. These commercials are notable in that they contain a melody and a slogan – ‘Say the name: OMA margarine’ – that have basically remained the same for 70 years. Together these identifiers make OMA an interesting Danish case to study. With reference to Ann Rigney’s memorial practices or mechanisms, the study aims to demonstrate how the auditory aspects of Danish margarine commercials for frying tend to be limited in variety: in general, the soundtracks of margarine commercials seem to merge into one, they are somewhat alike. The OMA commercials are no exception, but the OMA melody makes a distinction. In general the soundtracks of OMA margarine commercials (and the use of melody) seem to have shifted from using a predominantly semantic causal soundtrack to tracks using aesthetic and musicalised elements which are supposed to arouse more sensuous feelings in the consumers.
|
2022-02-08T09:07:33.388Z
|
98,409,811 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2478/s11532-012-0132-0",
"MAG": "2044373275",
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://doi.org/10.2478/s11532-012-0132-0"
}
|
Environmental tobacco smoke (ETS) contains many toxic compounds which include substances classified as aldehydes (e.g. formaldehyde) and inorganic substances such as cyanide ions. The information on the determination of these compounds in water is available, but the monitoring data on the level of these substances in human body fluids are still lacking. In this work the procedure for determining cyanide ions and formaldehyde in samples of human nasal discharge by simple spectrophotometric technique is presented.
|
2022-07-31T12:03:37.466Z
|
251,745,738 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1145/3511808.3557123",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Interleaving is an online evaluation technique that has shown to be orders of magnitude more sensitive than traditional A/B tests. It presents users with a single merged result of the compared rankings and then attributes user actions back to the evaluated rankers. Different interleaving methods in the literature have their advantages and limitations with respect to unbiasedness, sensitivity, preservation of user experience, and implementation and computation complexity. We propose a new interleaving method that utilizes a counterfactual evaluation framework for credit attribution while sticking to the simple ranking merge policy of balanced interleaving, and formally derive an unbiased estimator for comparing rankers with theoretical guarantees. We then confirm the effectiveness of our method with both synthetic and real experiments. We also discuss practical considerations of bringing different interleaving methods from the literature into a large-scale experiment, and show that our method achieves a favorable tradeoff in implementation and computation complexity while preserving statistical power and reliability. We have successfully implemented our method and produced consistent conclusions at the scale of billions of search queries. We report 10 online experiments that apply our method to e-commerce search, and observe a 60x sensitivity gain over A/B tests. We also find high correlations between our proposed estimator and corresponding A/B metrics, which helps interpret interleaving results in the magnitude of A/B measurements.
|
2022-10-20T13:18:51.134Z
|
237,471,356 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/molecules26175152",
"MAG": null,
"PubMedCentral": "8433905"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/1420-3049/26/17/5152/pdf?version=1630029681"
}
|
Radiation-induced fibrosis (RIF) is a serious, yet incurable, complication of external beam radiation therapy for the treatment of cancer. Macrophages are key cellular actors in RIF because of their ability to produce reactive oxidants, such as reactive oxygen species (ROS) and inflammatory cytokines that, in turn, are the drivers of pro-fibrotic pathways. In a previous work, we showed that phagocytosis could be exploited to deliver the potent natural antioxidant astaxanthin specifically to macrophages. For this purpose, astaxanthin encapsulated into µm-sized protein particles could specifically target macrophages that can uptake the particles by phagocytosis. In these cells, astaxanthin microparticles significantly reduced intracellular ROS levels and the secretion of bioactive TGFβ and increased cell survival after radiation treatments. Here we show that pentoxifylline, a drug currently used for the treatment of muscle pain resulting from peripheral artery disease, amplifies the effects of astaxanthin microparticles on J774A.1 macrophages. Combination treatments with pentoxifylline and encapsulated astaxanthin might reduce the risk of RIF in cancer patients.
|
2022-12-06T18:10:05.590Z
|
85,999,504 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1614/WS-D-13-00138.1",
"MAG": "2156288414",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract Organic agricultural systems increase the complexity of weed management, leading organic farmers to cite weeds as one of the greatest barriers to organic production. Integrated Weed Management (IWM) systems have been developed to address the ecological implications of weeds and weed management in cropping systems, but adoption is minimal. Organic agriculture offers a favorable context for application of IWM, as both approaches are motivated by concern for environmental quality and agricultural sustainability. However, adoption of IWM on organic farms is poorly understood due to limited data on weed management practices used, absence of an IWM adoption metric, and insufficient consideration given to the unique farming contexts within which weed management decisions are made. Therefore, this study aimed to (1) characterize organic weed management systems; (2) identify motivations for, and barriers to, selection of weed management practices; and (3) generate guiding principles for effective targeting of weed management outreach. We surveyed Midwestern organic growers to determine how specified psychosocial, demographic, and farm structure factors influence selection of weed management practices. Cluster analysis of the data detected three disparate, yet scaled, approaches to organic weed management. Clusters were distinguished by perspective regarding weeds and the number of weed management practices used. Categorization of individual farms within the identified approaches was influenced by primary farm products as well as farmer education, years farming, and information-seeking behavior. The proposed conceptual model allows weed management educators to target outreach for enhanced compatibility of farming contexts and weed management technologies.
|
2022-12-14T06:54:05.613Z
|
211,041,186 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1145/3372244",
"MAG": "3014430208",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A method of learning and modeling unit embeddings using deep neutral networks (DNNs) is presented in this article for unit-selection-based Mandarin speech synthesis. Here, a unit embedding is defined as a fixed-length embedding vector for a phone-sized unit candidate in a corpus. Modeling phone-sized embedding vectors instead of frame-sized acoustic features can better measure the long-term dependencies among consecutive units in an utterance. First, a DNN with an embedding layer is built to learn the embedding vectors of all unit candidates in the corpus from scratch. In order to enable the extracted embedding vectors to carry both acoustic and linguistic information of unit candidates, a multitarget learning strategy is designed for the DNN. Its optional prediction targets include frame-level acoustic features, unit durations, monophone and tone identifiers, and context classes. Then, another two DNNs are constructed to map linguistic features toward the extracted embedding vectors. One of them employs the unit vectors of preceding phones besides the linguistic features of current phone as its input. At synthesis time, the distances between the unit vectors predicted by these two DNNs and the ones derived from unit candidates are used as a part of the target cost and a part of the concatenation cost, respectively. Our experiments on a Mandarin speech synthesis corpus demonstrate that learning and modeling unit embeddings improve the naturalness of hidden Markov model (HMM)-based unit selection speech synthesis. Furthermore, integrating multiple targets for learning unit embeddings achieves better performance than using only acoustic targets according to our subjective evaluation results.
|
2022-12-18T10:48:53.241Z
|
241,359,430 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.18554/cimeac.v9i1.3842",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "http://seer.uftm.edu.br/revistaeletronica/index.php/cimeac/article/download/3842/3861"
}
|
Editorial - v. 9, n. 1, 2019.
|
2022-01-23T02:51:59.709Z
|
218,608,927 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1210/jendso/bvaa046.1093",
"MAG": "3022316929",
"PubMedCentral": "7207628"
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://doi.org/10.1210/jendso/bvaa046.1093"
}
|
Abstract Introduction: More than one in four men develop symptomatic inguinal hernia, and hernia repair is the most commonly performed general surgical procedure in the US. Despite its prevalence, the molecular mechanisms causing inguinal hernia remain unclear. Aromatase, the key enzyme for the conversion of testosterone (T) to estradiol (E2), is present in human but not mouse skeletal muscle tissue. We recently demonstrated that robustly increased local E2 levels in lower abdominal muscle (LAM) tissue and decreased circulating T levels were associated with fibrosis and myocyte atrophy in LAM tissue, leading to severe scrotal (inguinal) hernia formation in a humanized aromatase transgenic mouse model (Aromhum) with a high LAM human aromatase expression. To further determine the relative role of estrogen and androgen in the development of inguinal hernia, we generated a novel mild Aromhum mouse model with lower LAM aromatase expression compared with the severe model. Methods: Mild Aromhum mice were followed for 6 months to determine hernia incidence and measure hernia size (n=30). We treated mild Aromhum mice with the aromatase inhibitor, letrozole (n=12) for 12 weeks. Circulating and LAM E2 levels in mice were measured using mass spectrometry. LAM tissue fibrosis and myocyte size were determined by Masson’s trichrome staining and H&E staining, respectively. Results: The mild Aromhum mice contain a single copy of the human aromatase genomic fragment with a truncated regulatory region, giving rise to significant but mildly elevated LAM E2 levels (2.5-fold) at 15 weeks of age. Interestingly, these mice maintain normal circulating T levels. Furthermore, we show that mildly increased LAM E2 without decreased circulating T levels cause hernia formation in about 88% of mild Aromhum mice in contrast to 100% hernia formation in mice containing the full-length human aromatase regulatory region (severe Aromhum model), suggesting that higher LAM estrogen and low serum T levels contribute to this severe phenotype. Treatment with an aromatase inhibitor restores LAM E2 levels to normal levels and completely prevents inguinal hernia formation in the mild Aromhum mice. In LAM fibroblasts of mild Aromhum mice, we find very high levels of estrogen receptor-α expression, which possibly mediates estrogen-induced hernia formation. Conclusion: Taken together, our findings from the mild Aromhum mouse model suggest that lower levels of estrogen excess in LAM are the primary driver of muscle atrophy and hernia formation because this mouse model do not exhibit circulating T deficiency. Our findings will constitute a starting point for dissecting the relative roles of estrogen and androgen action in inguinal hernia development. This has the potential to facilitate drug development to prevent and treat hernias, especially recurrent hernias after primary hernia repairs in vulnerable populations such as elderly men.
|
2022-01-27T03:17:54.746Z
|
225,297,509 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.23925/10.23925/1983-3156.2020v22i2p009-016",
"MAG": "3080851257",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://revistas.pucsp.br/index.php/emp/article/download/50250/32717"
}
|
Editorial do volume 22-2, 2020 em inglês
|
2022-07-09T09:01:14.415Z
|
249,645,296 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1542/hpeds.2021-006426",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
OBJECTIVES
Multisystem inflammatory syndrome in children (MIS-C) and e-cigarette or vaping product use-associated lung injury (EVALI) have significant overlap in clinical features, which can contribute to delay in identification and treatment. The objectives of this report were to identify and describe features that are common in both diagnoses and those that may help distinguish EVALI from MIS-C, and to highlight the diagnostic challenges observed at our tertiary medical center.
METHODS
We identified adolescents diagnosed with MIS-C who had respiratory or gastrointestinal symptoms and patients diagnosed with EVALI during the same time period. We compared demographics, history, clinical manifestations, laboratory findings, and features of the hospital course to determine areas of overlap between MIS-C and EVALI, as well as distinct features of each diagnosis. Mann-Whitney U test was used to compare continuous variables and Fisher's exact test was used to compare categorical variables.
RESULTS
We found that cardiovascular and mucocutaneous findings and thrombocytopenia were more common in MIS-C. EVALI patients had a higher degree of inflammation and history of antecedent weight loss. Providers at our institution were more likely to consider MIS-C than EVALI on the differential diagnosis, including in patients with vaping history and no evidence of previous severe acute respiratory syndrome coronavirus 2 infection.
CONCLUSIONS
This study emphasizes the need for a thorough collection of substance use history for all patients and consideration of EVALI in adolescents who present with respiratory compromise or gastrointestinal symptoms and systemic inflammation, particularly in the absence of severe acute respiratory syndrome coronavirus 2 exposure or cardiac findings characteristic of MIS-C.
|
2022-07-10T23:47:18.783Z
|
82,617,747 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1096/FASEBJ.29.1_SUPPLEMENT.960.15",
"MAG": "1118344287",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Previous data showed that mesenchymal stem cells (MSC) improved the renal morphology and attenuated inflammation, microvascular rarefaction, fibrosis and proteinuria in the stenotic kidney induced by 2 Kidney‐1 clip (2K‐1C) model. Here we evaluated the effect of MSC on the contralateral kidney. Three weeks after left renal artery occlusion, fluorescently tagged MSC (2x105 cells/animal) were injected weekly into the tail vein of the 2K‐1C rats. Flow cytometry showed labeled MSC in the cortex and medulla of both kidneys. MSC significantly reduced blood pressure (BP) and proteinuria in 2K‐1C rats. Glomerular filtration rate (GFR) was reduced in the stenotic kidney and renal plasma flow (RPF) was diminishedin both kidneys. MSC treatment improved these parameters in both kidneys. Contralateral kidney presented altered medullary morphology, fibrosis and vascular loss and MSC improved the morphology and decreased the fibrotic areas. In contrast, the efficiency of MSC improving vascular rarefaction was not observed in the contralateral kidney. Thus, MSC therapy in the 2K‐1C model prevented the progressive increase of BP, improved renal function, morphology and reduced fibrosis in both stenotic and contralateral kidneys but it was more efficient improving vascular rarefaction in stenotic than in contralateral kidney. This therapy may be a promising strategy to treat renovascular hypertension and its renal consequences in the near future. Supported by CAPES.
|
2022-08-24T09:13:18.027Z
|
18,367,080 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1137/S1064827502407822",
"MAG": "2071431995",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this paper we revisit and prove optimal-order and mesh-independent convergence of an inexact Newton method where the linear Jacobian systems are solved with multigrid techniques. This convergence is shown using Banach spaces and the norm $\max\{\|\cdot\|_1,\; \|\cdot\|_{0,\infty}\}$, a stronger norm than is used in previous work. These results are valid for a class of second-order, semilinear, finite element, elliptic problems posed on quasi-uniform grids. Numerical results are given which validate the theory.
|
2022-12-09T19:32:29.471Z
|
206,898,741 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/1467-8659.t01-1-00702",
"MAG": "2166442092",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
When rendering only directly visible objects, ray tracing a few levels of specular reflection from large, low‐curvaturesurfaces, and ray tracing shadows from point‐like light sources, the accessed geometry is coherentand a geometry cache performs well. But in many other cases, the accessed geometry is incoherent and a standardgeometry cache performs poorly: ray tracing of specular reflection from highly curved surfaces, tracing rays thatare many reflection levels deep, and distribution ray tracing for wide glossy reflection, global illumination, widesoft shadows, and ambient occlusion. Fortunately, less geometric accuracy is necessary in the incoherent cases.This observation can be formalized by looking at the ray differentials for different types of scattering: coherentrays have small differentials, while incoherent rays have large differentials. We utilize this observation to obtainefficient multiresolution caching of geometry and textures (including displacement maps) for classic and distributionray tracing in complex scenes. We use an existing multiresolution caching scheme (originally developed forscanline rendering) for textures and displacement maps, and introduce a multiresolution geometry caching schemefor tessellated surfaces. The multiresolution geometry caching scheme makes it possible to efficiently render scenesthat, if fully tessellated, would use 100 times more memory than the geometry cache size.
|
2022-12-19T07:40:49.333Z
|
85,942,066 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/ZOO.20054",
"MAG": "2144130414",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Demographic models are important tools for assessing population status, diagnosing potential causes of population decline, and comparing management strategies that might change population trajectory. The population of Asian elephants (Elephas maximus) maintained in North American zoos has been declining for the past decade, and Wiese ([2000] Zoo. Biol. 19:299–309) predicted a continued decline in the population using an age-based matrix model. We developed an individual-based model to further explore the demographic issues of the population. Our model allowed us to quantitatively evaluate the prospects for slowing or reversing the decline given the potential management strategies of improving reproduction, reducing infant mortality, altering birth sex ratio, and recruiting additional individuals from outside the population. Our simulations showed that if current demographic trends continued, the population would continue to decline at 2%/year. It was possible to create sustainable simulations, but these required a large increase in the annual number of births produced. Increasing reproduction was the most effective strategy to slow the decline, whereas other management strategies had the most impact when combined with increases in reproduction. Almost all simulations resulted in large changes in population structure, with increases in the male population and decreases in the female population. Given the population's demographic issues, it will be difficult to either increase the population substantially or sustain it at its current size. Zoo Biol 25:201–218, 2006. © 2005 Wiley-Liss, Inc.
|
2022-12-18T10:07:43.369Z
|
238,995,936 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.28991/esj-2021-01308",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.ijournalse.org/index.php/ESJ/article/download/650/pdf"
}
|
One source of learning in universities is a digital library. In the era of industry 4.0, most universities have implemented digital libraries in supporting the learning process. However, the reality shows that digital library management is still ineffective. Therefore, the implementation of digital libraries needs to be evaluated for determining the digital library effectiveness used as learning resources in supporting the learning process in universities. Many evaluation tools are used to evaluate the effectiveness of digital libraries but have not provided accurate recommendation results to support decision-making. This research presents an innovation in the form of an evaluation tool that can be used to evaluate the digital library effectiveness in universities. That evaluation tool is called the Alkin-WP-based digital library evaluation software. This software is a desktop platform that contains aspects of measuring the digital library effectiveness by referring to the components of the Alkin evaluation model and the WP (Weighted Product) method. This research aimed to show the effectiveness level of the utilization of Alkin-WP-based digital library evaluation software. This research method was R & D (Research & Development) which refers to the ten development stages of the Borg and Gall model. In this research, development was focused only on a few stages, included: usage trials, final product revision, dissemination, and implementation. The subjects involved in assessing the implementation/utilization of the Alkin-WP-based digital library evaluation software were 35 people, in the usage trials were six people, in product revision were three people, and at the stage of dissemination were 15 people. The tools used to collect data were questionnaires and interview guidelines. The data analysis technique used was descriptive quantitative. The effectiveness level of utilizing the Alkin-WP-based digital library evaluation software was 88.34%. It showed that the evaluation software had effective. The impact of this research results on the scientific field of educational evaluation is being able to show the existence of a new evaluation tool based on educational evaluation and artificial intelligence. That evaluation tool can easier for library heads to make policies for revamping digital library services based on accurate recommendations. Doi: 10.28991/esj-2021-01308 Full Text: PDF
|
2022-12-20T16:01:41.890Z
|
34,751,581 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1101/GAD.12.14.2153",
"MAG": "2119727612",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Smads regulate transcription of defined genes in response to TGF-beta receptor activation, although the mechanisms of Smad-mediated transcription are not well understood. We demonstrate that the TGF-beta-inducible Smad3 uses the tumor suppressor Smad4/DPC4 and CBP/p300 as transcriptional coactivators, which associate with Smad3 in response to TGF-beta. The association of CBP with Smad3 was localized to the carboxyl terminus of Smad3, which is required for transcriptional activation, and a defined segment in CBP. Furthermore, CBP/p300 stimulated both TGF-beta- and Smad-induced transcription in a Smad4/DPC4-dependent fashion. Smad3 transactivation and TGF-beta-induced transcription were inhibited by expressing E1A, which interferes with CBP functions. The coactivator functions and physical interactions of Smad4 and CBP/p300 with Smad3 allow a model for the induction of gene expression in response to TGF-beta.
|
2022-12-20T20:27:25.194Z
|
234,407,048 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.46600/ALMILAL.V2I2.153",
"MAG": "3128846274",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
حقوق الإنسان المدنية من خلال وثيقة المدينة: دراسة مقارنة بالمواثيق الدولية
This research aims to give the reader a comprehensive view of civil human rights through a comparative study of the Charter of Medina and international conventions. The Charter of Medina designed the foundation of a multi-religious Islamic state in Medina, as it was signed to end the rancorous intertribal aggression among the opposing tribes of Banu ’Aws and Banu Khazraj in Medina and to uphold harmony and co-operation among all Medinan groups. Its major accomplishment was fetching confrontational clans together to form a community and inaugurating long term peace among them. It put an end to the predominant disorder and sheltered the life, self-determination, property and religious freedom for all people. The paper highlights the relevance and importance of civil human rights through the Charter of Medina as well as international conventions in the up-to-date worldwide civilization. The present research examines the historical document of Charter of Medina and elucidates it through examples from Quran and Sunnah as well as compares its core values with international conventions. In this regard the views of the past and contemporary scholarship are also discussed to analyze the challenges and issues of current time. In recent times the efforts and implications of civil human rights have unfolded in many different ways so it is very important for Muslims to know and to relate the Sharī’ah ruling regarding it. The research concludes that as compare to the international convections the system of justice in the Islamic Sharī’ah ensures all rights and with liabilities.
|
2022-01-27T10:32:11.619Z
|
161,832,859 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.24114/STUDIA.V3I2.1247",
"MAG": "1442012600",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Das Ziel der Untersuchung ist, festzustellen, wie die Benutzung de r Methode Picture and Picture zur Steigerung der Schreib kompetenz der Schuler in der Klasse XI IPA 1 SMA HKBP Sidorame Medan Jahrgang 201 3-201 4 ist. Diese Untersuchung ist eine Klassenhandlungsuntersuchung, die in zwei Zyklen durchgefuhrt wird. Jeder Zyklus besteht aus Planung, Handlung, Beobachtung, und Reflexion. Jeder Zyklus besteht aus drei Treffen, jedes Treffen dauert etwa 45 Minuten. Die Daten dieser Untersuchung werden auch durch einen Vorwissenstest, und Posttest im ersten Zyklus und zweiten Zyklus, Interview und die Umfrage, wahrend des Lernprozesses gesammelt. Als Instrument fur den Handlung s test dient das Bewertungskriterium der A1 . Als Instrument fur den Nontest werden Observationsmittel, Dokumentationen und eine Umfrage angewendet. Die Probanden in dieser Untersuchung sind alle S chuler in der Klasse XI IP A S MA HKBP Sidorame Medan Jahrgang 2013-2014 . Die Schuler sind 39 Personen. Von dieser Untersuchung kann zusammengefasst werden, dass im Vorwissenstes t, zwanzig Schulerin (51,2%) den Erfolgsindikator erreicht h aben , und 19 Schuler (48,8%) waren nicht bestanden . Im Zyklus I haben 25 Schuler (64,05%) den Erfolgsindikator erreicht und 14 Schuler (35,8%) sind nicht bestanden. Im Zyklus II haben 32 Schuler (82,05%) den Erfolgsindikator erreicht, und 7 Schuler (17,94%) sind nicht bestanden. Schlusselworter : Der Picture and Picture Methode , die Schreibkompetenz der Schuler
|
2022-02-08T22:02:34.753Z
|
93,108,022 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/AIC.690430203",
"MAG": "1983417432",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The convective diffusion equations were used to obtain mean concentrations and concentration fluctuation covariances during turbulent reactive mixing of fast reversible reactions. The mean concentrations are directly applicable to reactions that are much faster than the mixing, while the covariances can serve as a first approximation closure for slower reactions. The covariances should also be useful for testing more general closure models. Numerical examples are presented for the simple mass-action rate law with stoichiometric coefficients of unity.
|
2022-02-10T18:02:25.277Z
|
251,190,212 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.33650/pjp.v8i2.2938",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBYSA",
"status": "GOLD",
"url": "https://ejournal.unuja.ac.id/index.php/pedagogik/article/download/2938/1084"
}
|
This study aims to determine the perceptions of English Education students at Nurul Jadid University, Probolinggo towards online learning for intermediate listening courses via E-learning during the Covid-19 pandemic. After one semester's learning process, the qualitative descriptive method was carried out by distributing questionnaires using Google Form to 48 2nd semester students of English Education at Nurul Jadid University, Probolinggo. The results of this study stated that the performance aspects of using UNUJA's E-learning for Intermediate Listening courses are as expected, the effort aspect of using E-Learning UNUJA for Intermediate Listening courses are as expected, social factors of using E-Learning UNUJA for Intermediate Listening courses are still less than expected, aspects of conditions that facilitate the use of E-Learning UNUJA for Intermediate Listening courses are considered very good, student interest in using E-Learning UNUJA for Intermediate Listening courses is very high, and behavioural aspects of using E-Learning UNUJA for Intermediate Listening is good.
|
2022-08-20T17:06:05.826Z
|
25,850,448 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/(SICI)1096-9861(19980914)399:1<110::AID-CNE9>3.0.CO;2-4",
"MAG": "2022929721",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The medial geniculate body (MGB) is a thalamic structure that provides vital information flow to the forebrain for complex acoustic processing. The development of cytoarchitectural features of the MGB was examined in rat to identify age‐related patterns of growth in major geniculate compartments that have been described previously (Clerici and Coleman [1990] J. Comp. Neurol. 297:14–31; Clerici et al. [1990] J. Comp. Neurol. 297:32–54): the ventral (MGv), dorsal (MGd), and medial (MGm) divisions. Results show that, on the day of parturition, all major nuclei of each division are characterized, including the ovoid (OV) and ventral (LV) nuclei of MGv; the dorsal, deep dorsal (DD), caudodorsal, limitans, and suprageniculate nuclei of MGd; and the MGm. The MGv and MGd, which display comparable areas at birth, show rapid growth to postnatal day 7 (PND7), which then slows until PND11, around the time of ear canal opening; subsequently, MGv accelerates growth to reach larger adult size. From PND11 to PND16, thionin facilitates parcellation by extensive staining of dendritic processes of MGd, MGm, and lateral posterior nucleus neurons but not neurons of the MGv or the dorsal lateral geniculate nucleus. Golgi stains after birth reveal restricted dendritic arborizations in MGv cells and dichotomous branching patterns of MGd neurons. Somal size in MGB increases dramatically subsequent to afferent innervation and again following onset of auditory function. Somal growth occurs between all postnatal age groups tested for OV, LV, and DD nuclei, although LV segments related to high and low frequencies do not differ. Cell packing density predicts the expanse of major MGB divisions better than somal size. These results demonstrate the integrity and growth patterns of MGB nuclei and divisions from nascence and provide a substrate for subsequent study of anatomical and physiological development of the MGB. J. Comp. Neurol. 399:110–124, 1998.© 1998 Wiley‐Liss, Inc.
|
2022-09-14T01:51:06.299Z
|
244,416,981 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/neuonc/noab196.424",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://academic.oup.com/neuro-oncology/article-pdf/23/Supplement_6/vi107/41140440/noab196.424.pdf"
}
|
Tumor Treating Fields (TTF) Therapy is an FDA-approved therapy in the first line and recurrent setting for glioblastoma. Despite Phase 3 evidence showing improved survival, it is not uniformly utilized despite its availability. This qualitative prospective study interviewed glioblastoma patients to better understand key driving factors for decision making.
Adult glioblastoma patients who were offered TTF and who signed IRB approved consent were included. Patients participated in a one-time recorded interview with the researchers from the Northwestern University Department of Medical Social Sciences and were asked about factors shaping their decision to use or not use TTF.
40 patients were enrolled with a mean age of 53 years, 92.5% were white and 60% were male. Of the 33 (82.5%) participants who accepted TTF, 23 (69.7%) reported their physician recommending TTF, 8 (24.2%) reported physician neutrality toward TTF, and 2 (6.1%) said their physician advised against TTF. Among the 7 (17.5%) participants who did not choose TTF, 4 (57.1%) reported physician neutrality, 2 (28.6%) reported that their physician advised against TTF, and 1 (14.3%) reported that their physician recommended TTF. Participants who decided against TTF stated that head shaving, appearing sick, and inconvenience of wearing/carrying the device most influenced their decision. For those choosing to use TTF, the most influential factors were extending life and following their doctor's opinion; other factors included level of familial support and the clinical evidence supporting TTF.
This clinical study was a collaboration with the Medical Social Sciences team to better understand the key factors that drive patient decision making with TTF. Findings suggest that physician support and positive Phase 3 results are among the key decision-making factors. Properly understanding the path to patients’ decision making is crucial in optimizing use of TTF and other therapeutic decisions for glioblastoma patients.
|
2022-11-25T00:38:25.825Z
|
171,895,332 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.15581/021.10.5060",
"MAG": "2593721365",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "HYBRID",
"url": "https://revistas.unav.edu/index.php/revista-de-medicina/article/download/5060/4379"
}
|
Se exponen los resultados personales sobre la duodenografía hipotónica, realizada en 75 pacientes en los que se sospechaba una afección pancreática.
Se aconseja la administración por vía venosa, con lo que se el tiempo de exploración.
Es una exploración de técnica sencilla, que en ninguna ocasión ha producido molestias que requieran cuidados especiales; y que es de gran valor para el diagnóstico diferencial entre pancreatitis crónica y neoplasias de cabeza de en sus fases iniciales.
Se insiste en la frecuente coincidencia de divertículos en el borde interno de D2 con pancreatitis.
|
2022-10-28T00:19:18.365Z
|
120,086,229 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1748-0221/7/08/P08016",
"MAG": "2003949877",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
With the combined view on the physical space and the medical imaging data, augmented reality (AR) visualization can provide perceptive advantages during image-guided surgery (IGS). However, the imaging data are usually captured before surgery and might be different from the up-to-date one due to natural shift of soft tissues. This study presents an AR-enhanced IGS system which is capable to correct the movement of soft tissues from the pre-operative CT images by using intra-operative ultrasound images. First, with reconstructing 2-D free-hand ultrasound images to 3-D volume data, the system applies a Mutual-Information based registration algorithm to estimate the deformation between pre-operative and intra-operative ultrasound images. The estimated deformation transform describes the movement of soft tissues and is then applied to the pre-operative CT images which provide high-resolution anatomical information. As a result, the system thus displays the fusion of the corrected CT images or the real-time 2-D ultrasound images with the patient in the physical space through a head mounted display device, providing an immersive augmented-reality environment. For the performance validation of the proposed system, a brain phantom was utilized to simulate brain-shift scenario. Experimental results reveal that when the shift of an artificial tumor is from 5mm ~ 12mm, the correction rates can be improved from 32% ~ 45% to 87% ~ 95% by using the proposed system.
|
2022-11-17T18:24:00.233Z
|
30,083,491 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1364/JOSAA.24.000265",
"MAG": "2499856433",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We detail the development and implementation of a global ablation model that incorporates a dynamically changing tissue absorption coefficient. Detailed spectroscopic measurements rule out plasma-shielding effects during the laser-tissue interaction and thereby support a photochemical mechanism. The model predicts ablation rate behavior that agrees well with a variety of experimental ablation rate data and that substantially deviates from a static Beer-Lambert model. The dynamic model predicts an enhancement in the tissue absorption coefficient of about 25%-50% as compared with the initial, static value. In addition, the model predicts an increase in the tissue ablation rate as corneal hydration increases, which may provide additional insight into variations in refractive surgery outcome.
|
2022-12-10T18:21:59.210Z
|
12,337,476 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3892/etm.2014.2020",
"MAG": "2013264638",
"PubMedCentral": "4217784"
},
"license": null,
"status": "GOLD",
"url": "https://www.spandidos-publications.com/etm/8/6/1783/download"
}
|
The present study explored the effects of epigallocatechin gallate (EGCG) on the cell cycle, proliferation and apoptosis of the nasopharyngeal carcinoma cell line CNE2 in vitro. The proliferation of CNE2 cells was detected using the cell counting kit-8 method. Cell cycle distribution and apoptosis were detected using flow cytometry. The human telomerase reverse transcriptase (hTERT) mRNA expression was determined using reverse transcription polymerase chain reactions. The protein expression of hTERT and Myc proto-oncogene protein (c-Myc) was observed using western blot analysis. EGCG inhibited the proliferation of CNE2 cells in a concentration-dependent manner (P<0.05) and blocked the cell cycle progression of the cells. In the low concentration (100 μg/ml) group, the cell cycle arrest showed a time-dependent manner. However, as the concentration increased and action time was prolonged, this time dependency became less marked. EGCG promoted the apoptosis of CNE2 cells in a time-dependent manner. In addition, EGCG downregulated the mRNA and protein expression of hTERT and downregulated the expression of c-Myc protein. Downregulation of the expression of hTERT and c-Myc was more evident in the high-dose group (200 μg/mL). In conclusion, EGCG has proliferation-inhibiting, cell cycle-blocking and apoptosis-promoting effects on CNE2 cells. EGCG may be developed into an auxiliary therapeutic agent for the treatment of nasopharyngeal carcinoma.
|
2022-12-17T21:22:03.873Z
|
42,336,120 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1136/adc.51.11.875",
"MAG": "2024778979",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://adc.bmj.com/content/51/11/875.full.pdf"
}
|
The relation between the true plasma creatinine concentration (Pc) and the glomerular filtration rate corrected for body surface area (GFR/SA) was investigated in 108 individuals, and the following formula was derived: GFR/SA (ml/min per 1-73m2SA) = 0-43 Ht (cm)/Pc (mg/100 ml). This formula was tested in a second group of 83 children, and its accuracy and precision was compared to the 24-hour creatinine clearance. It was found to be superior to the creatinine clearance overall, and was as good, even if all results involving suspect 24-hour-urine collections were eliminated from analysis. The formula in SI usage is: GFR/SA (ml/min per 1-73 m2SA) = 38 Ht (cm)1Pc (mumol/l).
|
2022-12-20T02:18:29.362Z
|
149,387,729 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1515/ijtr-2017-0001",
"MAG": "2790370106",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://content.sciendo.com/downloadpdf/journals/ijtr/4/1/article-p18.pdf"
}
|
Abstract Transformative researchers have the potential to contribute to both personal and societal transformation. In this article, I argue that the two are intertwined and that personal transformation is a necessary component of research that is designed to support change at the societal level in the form of furthering human rights and social justice. I describe a transformative framework that examines assumptions related to ethics, the nature of reality, epistemology, and methodology that can guide researchers who choose to address both the personal and societal levels of transformation. Ethically, researchers need to examine who they are and who they are in relation to the community in which they are working. This process goes beyond self-examination to a critical analysis of the cultural blinders that might obscure our ability to contribute to positive impacts. I put forth the hypothesis that if we design our research so that it explicitly addresses issues of discrimination and oppression that the probability of personal and social transformation increases.
|
2022-12-25T21:59:00.342Z
|
237,806,292 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.31154/cogito.v7i1.286.52-60",
"MAG": "3179373472",
"PubMedCentral": null
},
"license": "CCBYSA",
"status": "GOLD",
"url": "http://cogito.unklab.ac.id/index.php/cogito/article/download/286/170"
}
|
Saat ini perkembangan teknologi yang pesat telah merubah prilaku para pelanggan khususnya dalam cara berbelanja dimana pembelian barang ataupun jasa dapat dilakukan dengan mudah melalui internet. Walaupun terdapat kemudahan yang ditawarkan oleh teknologi tersebut, masih terdapat sebagian segmen pelanggan yang masih enggan ataupun takut untuk menggunakannya. Penelitian ini dibuat untuk mengetahui persepsi pelanggan dua kelompok generasi yakni generasi X dan generasi Y terkait kenyamanan dalam berbelanja secara online. Metode yang digunakan dalam penelitian ini adalah analisis deskriptif dan uji beda yakni independent sample t test yang bertujuan untuk mengetahui apakah terdapat perbedaan yang signifikan antara kelompok generasi X dan generasi Y jika ditinjau dari sisi kenyamanan berbelanja secara online. Terdapat 366 responden dalam penelitian ini. Hasil penelitian ini mendapati bahwa tidak terdapat perbedaan yang signifikan antara generasi X dan generasi Y ditinjau dari persepsi kenyamanan berbelanja secara online, kecuali untuk kategori terkait perhatian dari toko online dimana didapati generasi Y memiliki persepsi yang lebih baik dibandingkan dengan generasi X. Kata kunci— Berbelanja secara online, Generasi X, Generasi Y
|
2022-01-24T19:09:09.412Z
|
237,802,008 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21467/proceedings.115.11",
"MAG": "3177196588",
"PubMedCentral": null
},
"license": "CCBYNC",
"status": "HYBRID",
"url": "https://doi.org/10.21467/proceedings.115.11"
}
|
Drunken Driving is one of the most fatal causes of premature deaths around the world. According to WHO, about 20% of the fatally injured drivers have excess alcohol in their blood in high income countries whereas the figures may be as high as 69% in low and middle income countries. In India alone, there have been 38,000 road mishaps due to drunk driving in the past three years according to the latest report of Ministry of Road Transport and Highways. The objective of this paper is to make human driving safer and overcome such incidences. The present paper describes the process of detection of alcohol in sample breath testing, developed using Arduino and Arduino Integrated Design Environment (IDE). The system will sense the alcohol concentration in breath and control the switching of ignition engine according the data it receives. Also, it allows the driver a delay time in case the breath is detected after the vehicle has started to avoid traffic mismanagement. Finally, it will send an SMS alert to his/her relatives/close friends to alert them of possible drunken driving incident and prevent it.
|
2022-02-07T20:41:31.913Z
|
43,912,476 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1103/PHYSREVB.47.1489",
"MAG": "2085833470",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We have performed theoretical studies on Raman scattering of GaAs-AlAs superlattices. Both effects of superlattice phonons and electronic structures are included in our calculation. For phonons in superlattices, we used a rigid-ion model that takes into account the long-range Coulomb interaction properly. Combining it with a bond-orbital model for the electronic states in superlattices, we have studied nonresonant Raman scattering of GaAs/AlAs superlattices for both optical phonons and acoustic phonons. For optical phonons, we have considered both z(xy)z and z(xx)z geometries
|
2022-02-12T01:44:01.201Z
|
149,059,645 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.6092/2282-1619/2017.5.1526",
"MAG": "2626523250",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The volume, edited by Daniele La Barbera, Luigi Baldari and Lucia Sideli, deals with the extended contributions of the Italian Society of Medical Psychotherapy Congress, wich took place in April 2015 in Messina. The papers exposed have been focused on various topic related to psychosis, analysed from several scientific point of view with a common thread.
|
2022-12-20T02:55:43.854Z
|
110,683,482 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.9708/JKSCI/2012.17.12.001",
"MAG": "2054067424",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this paper, we propose an patient monitoring system which is suitable for mobile healthcare system. The mobile healthcare system is using portable device such as smartphone and it consists of small computing device. The mobile healthcare system is carry out same performance with desktop computer. We designed medical message structure based on TinyOS to transmit patient`s biometric data on the smartphone of medical team, patient and family over the mobile carrier environment, and ported successfully in HBE-Ubi-ZigbeX using NesC. And We confirmed reliable transmission of biometric data on the smartphone by implementing the Android OS based patient information monitoring application to check the status of patient for medical team, patient and family.
|
2022-12-29T17:50:24.533Z
|
78,091,550 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/acs.analchem.8b05670",
"MAG": "2921226250",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Reduced graphene oxide/tin dioxide (RGO/SnO2) binary nanocomposite for acetone sensing performance was successfully studied and applied in exhaled breath detection. The influence of structural characteristics was explored by synthesizing the composite (RGO/SnO2) using the solvothermal method (GS-I) and the hydrothermal method (GS-II) by the chemical route and mechanical mixing, respectively. The nanocomposites characterized by X-ray diffraction (XRD), high-resolution transmission electron microscopy (HRTEM), Fourier transform-infrared spectroscopy (FT-IR), and Brunauer-Emmett-Teller (BET) revealed that GS-I exhibited better surface area, surface energy and showed enhanced gas response than GS-II at an operating temperature of 200 °C. These sensors exhibited comparable response in humid environment as well, suitable for acetone sensing in exhaled breath that clearly distinguishes between healthy and diabetes subjects. The enhanced response at lower concentrations was attributed to the synergistic effect at the RGO/SnO2 interface. These results indicate that modification in the structural characteristics of RGO/SnO2 nanocomposite enhances the sensing property. Furthermore, it proved to be a promising material for potential application for point-of care, noninvasive diabetes detection.
|
2022-12-29T17:43:23.844Z
|
13,827,351 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/jacs.6b12250",
"MAG": "2576983657",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Ni-Fe oxyhydroxides are the most active known electrocatalysts for the oxygen evolution reaction (OER) in alkaline electrolytes and are therefore of great scientific and technological importance in the context of electrochemical energy conversion. Here we uncover, investigate, and discuss previously unaddressed effects of conductive supports and the electrolyte pH on the Ni-Fe(OOH) catalyst redox behavior and catalytic OER activity, combining in situ UV-vis spectro-electrochemistry, operando electrochemical mass spectrometry (DEMS), and in situ cryo X-ray absorption spectroscopy (XAS). Supports and pH > 13 strongly enhanced the precatalytic voltammetric charge of the Ni-Fe oxyhydroxide redox peak couple, shifted them more cathodically, and caused a 2-3-fold increase in the catalytic OER activity. Analysis of DEMS-based faradaic oxygen efficiency and electrochemical UV-vis traces consistently confirmed our voltammetric observations, evidencing both a more cathodic O2 release and a more cathodic onset of Ni oxidation at higher pH. Using UV-vis, which can monitor the amount of oxidized Ni+3/+4 in situ, confirmed an earlier onset of the redox process at high electrolyte pH and further provided evidence of a smaller fraction of Ni+3/+4 in mixed Ni-Fe centers, confirming the unresolved paradox of a reduced metal redox activity with increasing Fe content. A nonmonotonic super-Nernstian pH dependence of the redox peaks with increasing Fe content-displaying Pourbaix slopes as steep as -120 mV/pH-suggested a two proton-one electron transfer. We explain and discuss the experimental pH effects using refined coupled (PCET) and decoupled proton transfer-electron transfer (PT/ET) schemes involving negatively charged oxygenate ligands generated at Fe centers. Together, we offer new insight into the catalytic reaction dynamics and associated catalyst redox chemistry of the most important class of alkaline OER catalysts.
|
2023-01-01T17:20:03.104Z
|
230,619,733 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.24264/icams-2020.i.10",
"MAG": "3113044398",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://doi.org/10.24264/icams-2020.i.10"
}
|
Determination of values and dependencies of deformation and physical and mechanical properties of materials of shoe models and finished products. According to the results of theoretical, analytical and marketing research, a number of experimental tests of materials have been carried out to prove the practical significance of the work, namely tests for: deformation of the vamp part of the product, uniaxial and biaxial stretching, bending, dry and wet friction, adhesion, elongation and tearing. There has been established the nature of the distribution of the total elongations of the samples of the vamps cut from different areas of the leather, as well as the ability of the leather material to be formed when improving the shape of the product or changing the shape of the shoetree. The processes of deformation of the vamp part of shoe blanks, physical and mechanical properties of different groups of modern materials and values analysis of similarity of their deformation properties have been studied. There has been created a working model-transformer for carrying out preliminary measurement of clients’ feet at the individual order. The expediency of these works has been proved experimentally. A working version of a model-transformer for foot measurements has been made and as a result of the works approbation, a sample of shoes has been made. The ergonomic properties of the manufactured footwear have been improved due to the use of materials with enhanced physical and mechanical properties. The article investigates the deformation of the most vulnerable vamp part of the men's model of a typical model, as well as the physical and mechanical characteristics of leather materials for manufacturing models and shoes of this type. Providing high quality and comfort of footwear, accuracy of parameters selection of foot measurement, zones of beams and achievement of form stability of footwear with a top from genuine leathers has been predicted.
|
2022-02-07T22:38:49.477Z
|
196,500,251 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.25298/2221-8785-2017-15-4-447-453",
"MAG": "2767996124",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "http://journal-grsmu.by/index.php/ojs/article/download/2176/2002"
}
|
Background. Vitamin D can be associated with quality of life (QOL) and muscle strength in patients with chronic heart failure (CHF). Objective: to evaluate the relationship of level 25(OH)D with the indicators of muscle strength and QOL level in patients with CHF. Material and methods. 82 patients with CHF and D-hypovitaminosis were divided into 4 groups: I (n=26) – received cholecalciferol at a dose of 2000 IU/day, II (n=16) – at a dose of 1000 IU/day, III (n=23) – vitamin D-containing oral nutritional supplement, group IV (n=17) – basic therapy. QOL was assessed by Minnesota questionnaire (MQ), muscle strength of the upper limbs by carpal dynamometry, that of lower limbs– by chair lift test. 25(OH)D level was determined by ELISA. Follow-up was performed in 3 months. Results. 25(OH)D level was increased in all groups (p<0.05) and became higher in group I (p=0.0002) and group III (p=0.02) compared with group IV. In group I total score of MQ was reduced (p=0.02), right hand dynamometry value was increased (p=0.04), and in group III - left hand dynamometry was increased (p=0.04). The score of the MQ was negatively correlated with 25(OH)D level (R=-0.35, p=0.001) and right hand dynamometry (R=-0.22, p=0.04) initially and in follow-up (R=-0.24, p=0.03 and R=-0.25, p=0.03, respectively), and positively with chair lift test initially (R=0.24, p=0.03). Direct stepwise regression analysis showed that the dynamics of 25(OH)D level increase (b=-0.37, p=0.003) and a higher level of 25(OH)D in follow-up (b=-0.54, p=0, 04) affect the decrease in the score of the MQ. Conclusions. In patients with CHF 25(OH)D level is associated with QOL, its increase has a positive effect on QOL. QOL is associated with the muscular strength of the lower and upper extremities, the improvement of which is noted when taking vitamin D preparations.
|
2022-07-17T01:12:51.306Z
|
97,898 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1103/PHYSREVC.42.1731",
"MAG": "275868381",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A new experimental method has been implemented for precise measurements of neutron capture cross sections in the energy range from 3 to 200 keV. Neutrons are produced via the {sup 7}Li({ital p},{ital n}){sup 7}Be reaction using a pulsed 3-MV Van de Graaff accelerator. The neutron energy is determined by the time-of-flight (TOF) technique using flight paths of less than 1 m. Capture events are detected with a 4{pi} barium fluoride detector. This detector is characterized by a resolution in gamma-ray energy of 14% at 662 keV and 7% at 2.5 MeV, a time resolution of 500 ps, and a peak efficiency of 90% at 1 MeV. Capture events are registered with {similar to}95% probability above a gamma-ray threshold of 2.5 MeV. The combined effect of the relatively short primary flight path, the 10-cm inner radius of the detector sphere, and of the low capture cross section of BaF{sub 2} shifts the background due to capture of sample scattered neutrons in the scintillator to later TOF and therefore leaves the high-energy portion of the TOF spectrum undisturbed. The high efficiency and good energy resolution for capture gamma-rays yields a further reduction of this background by using only the relevant energy channelsmore » for data evaluation. In the first measurements with the new detector, the neutron capture cross sections of {sup 93}Nb, {sup 103}Rh, and {sup 181}Ta were determined in the energy range from 3 to 200 keV relative to gold as a standard. The cross-section ratios could be determined with overall systematic uncertainties of 0.7 to 0.8%; statistical uncertainties were less than 1% in the energy range from 20 to 100 keV, if the data are combined in 20-keV wide bins. This represents an improvement of factors 5--10 compared to existing experimental methods. The necessary sample masses were of the order of one gram.« less
|
2022-09-12T14:02:02.965Z
|
25,341,368 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1463-1326.2006.00591.x",
"MAG": "2159169885",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Growth hormone (GH) is generally considered to exert anti‐insulin actions, whereas insulin‐like growth factor I (IGF‐I) has insulin‐like properties. Paradoxically, GH deficient adults and those with acromegaly are both predisposed to insulin resistance, but one cannot extrapolate from these pathological conditions to determine the normal metabolic roles of GH and IGF‐I on glucose homeostasis. High doses of GH treatment have major effects on lipolysis, which plays a crucial role in promoting its anti‐insulin effects, whereas IGF‐I acts as an insulin sensitizer that does not exert any direct effect on lipolysis or lipogenesis. Under physiological conditions, the insulin‐sensitizing effect of IGF‐I is only evident after feeding when the bioavailability of circulating IGF‐I is increased. In contrast, many studies in GH deficient adults have consistently shown that GH replacement improves the body composition profile although these studies differ considerably in terms of age, the presence or absence of multiple pituitary hormone deficiency, and whether GH deficiency was childhood or adult‐onset. However, the improvement in body composition does not necessarily translate into improvements in insulin sensitivity presumably due to the anti‐insulin effects of high doses of GH therapy. More recently, we have found that a very low dose GH therapy (0.1 mg/day) improved insulin sensitivity without affecting body composition in GH‐deficient adults and in subjects with metabolic syndrome, and we postulate that these effects are mediated by its ability to increase free ‘bioavailable’ IGF‐I without the induction of lipolysis. These results raise the possibility that this low GH dose may play a role in preventing the decline of β‐cell function and the development of type 2 diabetes in these “high risk” subjects.
|
2022-12-11T01:51:13.192Z
|
118,233,324 |
{
"externalids": {
"ACL": null,
"ArXiv": "1402.6066",
"DOI": "10.4310/CAG.2018.V26.N6.A3",
"MAG": "2964114800",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
One of the most powerful theorems in metric geometry is the Arzela-Ascoli Theorem which provides a continuous limit for sequences of equicontinuous functions between two compact spaces. This theorem has been extended by Gromov and Grove-Petersen to sequences of functions with varying domains and ranges where the domains and the ranges respectively converge in the Gromov-Hausdorff sense to compact limit spaces. However such a powerful theorem does not hold when the domains and ranges only converge in the intrinsic flat sense due to the possible disappearance of points in the limit.
In this paper two Arzela-Ascoli Theorems are proven for intrinsic flat converging sequences of manifolds: one for uniformly Lipschitz functions with fixed range whose domains are converging in the intrinsic flat sense, and one for sequences of uniformly local isometries between spaces which are converging in the intrinsic flat sense. A basic Bolzano-Weierstrass Theorem is proven for sequences of points in such sequences of spaces. In addition it is proven that when a sequence of manifolds has a precompact intrinsic flat limit then the metric completion of the limit is the Gromov-Hausdorff limit of regions within those manifolds. Applications and suggested applications of these results are described in the final section of this paper.
|
2022-12-15T00:47:30.957Z
|
149,906,681 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1037/trm0000167",
"MAG": "2884373290",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
There is a dearth of knowledge on the role of cumulative trauma, stress, and minority oppression on recidivism among incarcerated elder population. The current study fills a gap in the literature by exploring the association between race, trauma, offense history, and recidivism among incarcerated elders. This study used a cross-sectional correlational design with 607 adult males aged 50 and older in a Northeastern state correctional system. Results of a series of moderation analyses revealed that drug offense history had a significant moderating effect on the relationship between trauma and recidivism. However, minority status or violent offense history was not found to be a significant moderator of the trauma and recidivism relationship. These findings suggest prevention and intervention efforts would benefit from incorporating trauma-informed approaches and principles of restorative justice that facilitate individual, family, and community healing.
|
2022-12-19T17:23:37.644Z
|
24,154,200 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1039/c5fo00150a",
"MAG": "1949802737",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Barley malt, a product of controlled germination, has been shown to produce high levels of butyric acid in the cecum and portal serum of rats and may therefore have anti-inflammatory effects. The aim of the study was to investigate how four barley malts, caramelized and colored malts, 50-malt and 350-malt, differing in functional characteristics concerning beta-glucan content and color, affect short-chain fatty acids (SCFA), barrier function and inflammation in the hindgut of rats fed high-fat diets. Male Wistar rats were given malt-supplemented high-fat diets for four weeks. Low and high-fat diets containing microcrystalline cellulose were incorporated as controls. All diets contained 70 g kg(-1) dietary fiber. The malt-fed groups were found to have had induced higher amounts of butyric and propionic acids in the hindgut and portal serum compared with controls, while cecal succinic acid only increased to a small extent. Fat increased the mRNA expression of tight junction proteins and Toll-like receptors (TLR) in the small intestine and distal colon of the rats, as well as the concentration of some amino acids in the portal plasma, but malt seemed to counteract these adverse effects to some extent. However, the high content of advanced glycation end-products (AGE) in caramelized malt tended to prohibit the positive effects on occludin in the small intestine and plasma amino acids seen with the other malt products. In conclusion, malting seems to be an interesting process for producing foods with positive health effects, but part of these effects may be destroyed if the malt contains a high content of AGE.
|
2022-12-24T17:17:14.910Z
|
36,191,977 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/bjps/axy024",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
According to Ian Hacking, some human kinds are subject to a peculiar type of classificatory instability: individuals change in reaction to being classified, which in turn leads to a revision of our understanding of the kind. Hacking’s claim that these ‘human interactive kinds’ cannot be natural kinds has been vehemently criticized on the grounds that similar patterns of instability occur in paradigmatic examples of natural kinds. I argue that the dialectic of the extant debate misses the core conceptual problem of human interactive kinds. The problem is not that these kinds are particularly unstable but ‘capricious’—their members behave in wayward, unexpected manners that defeats existing theoretical understanding. The reason for that, I argue, is that human interactive kinds are often ‘hybrid kinds’ consisting of a base kind and an associated status, which makes mechanisms that support patterns of change and stability systematically difficult to understand and predict. 1. Introduction2. The Extant Discussion 2.1. Hacking’s account of interactive kinds2.2. Classificatory feedback in non-human kinds3. Natural kinds and Ontological Instability 3.1. Understanding instability3.2. The problem of stabilizing feedback3.3. Summary4. Capricious Kinds 4.1. Biased conceptualization4.2. Studying social status5. Conclusion Introduction The Extant Discussion 2.1. Hacking’s account of interactive kinds2.2. Classificatory feedback in non-human kinds Hacking’s account of interactive kinds Classificatory feedback in non-human kinds Natural kinds and Ontological Instability 3.1. Understanding instability3.2. The problem of stabilizing feedback3.3. Summary Understanding instability The problem of stabilizing feedback Summary Capricious Kinds 4.1. Biased conceptualization4.2. Studying social status Biased conceptualization Studying social status Conclusion
|
2022-12-24T17:13:58.853Z
|
137,095,879 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1742-6596/234/2/022027",
"MAG": "2275570648",
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://doi.org/10.1088/1742-6596/234/2/022027"
}
|
The effects of magnetic nanoparticle doping on superconductivity of MgB2/Fe wires have been investigated. Fe2B and SiO2-coated Fe2B particles with average diameters 80 and 150 nm, respectively, were used as dopands. MgB2 wires with different nanoparticle contents (0, 3, 7.5, 12 wt.%) were sintered at temperature 750°C. The magnetoresistivity and critical current density Jc of wires were measured in the temperature range 2–40 K in magnetic field B ≤ 16 T. Both transport and magnetic Jc were determined. Superconducting transition temperature Tc of doped wires decreases quite rapidly with doping level (~ 0.5 K per wt.%). This results in the reduction of the irreversibility fields Birr(T) and critical current densities Jc(B,T) in doped samples (both at low (5 K) and high temperatures (20 K)). Common scaling of Jc(B,T) curves for doped and undoped wires indicates that the main mechanism of flux pinning is the same in both types of samples. Rather curved Kramer's plots for Jc of doped wires imply considerable inhomogeneity.
|
2022-12-30T00:54:38.330Z
|
233,970,924 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.18203/2320-1770.IJRCOG20210746",
"MAG": "3134849017",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Background: Intrapartum FHR monitoring is widely used during labour as changes in FHR precede brain injury, so timely response to abnormal FHR patterns might be effective in preventing it. There is a strong association between stillbirth and FGR which warrants intensive intrapartum fetal surveillance for optimal perinatal outcome. In this study we aimed to classify intrapartum FHR tracings into different categories in FGR pregnancies and correlate with perinatal outcome.Methods: A total 100 singleton pregnant women >34 weeks gestation with FGR were included in study. FHR tracings were followed throughout first and second stage of labour. FHR tracing were categorized into NICHD 3-tier classification as category I, II and III. Maternal and neonatal outome in each category were analysed.Results: Mean duration of category I tracings was 9.05 hours, category II was 7.66 hours and that of category III was 0.49 hours. During late active phase 25/95 patients with category I FHR tracings had vaginal delivery, 62/95 had category II FHR tracings, of which 95.1% had vaginal delivery and 4.9% had instrumental. 8/95 with category III FHR tracings required caesarean section. All patients with category I tracings had normal neonatal outcome, among patients with category II FHR tracings, 74.6% had normal whereas 25.4% had adverse outcome, all with category III FHR tracings had adverse outcome.Conclusions: Categorizing FHR tracings is helpful to distinguish neonates who are likely to have normal outcome from those who are at risk for fetal hypoxia. When the category II tracings are present, it requires more vigilant monitoring and decision taking.
|
2022-01-27T02:01:13.162Z
|
118,235,702 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S0074180900205895",
"MAG": "1651528866",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Studies of the atomic and molecular components of the interstellar medium in the vicinity of hot, massive stars have the potential of revealing a wealth of information on the way the star affects the distribution and physical state of the surrounding ISM during its various evolutionary phases, as well as potentially providing some information on the star itself and its past evolution. In this paper we present two examples of studies of the atomic and molecular gas around a massive star. We report on the presence of a large H I shell around the Wolf-Rayet star WR 134 (HD 191765). This bubble was not blown by the star in its present evolutionary phase but rather while it was an a-type star, on the main sequence. We also report on the discovery of filaments of H2 around a massive star in a much later evolutionary phase, i. e., after it has exploded as a supernova. The H2 filaments we have discovered in the supernova remnant W 44 are probably a direct manifestation of the interaction of the remnant with its surrounding medium.
|
2022-06-08T13:37:12.683Z
|
202,551,177 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1515/zatw.1897.17.1.183",
"MAG": null,
"PubMedCentral": null
},
"license": "CC0",
"status": "GREEN",
"url": "https://zenodo.org/record/2130384/files/article.pdf"
}
|
Udea carniolica n.sp. is described from the southern and southeastern Alps and compared with the closely related Udea murinalis (FISCHER VON RÖSLERSTAMM, [1842]). The moth and genitalia of both sexes are figured. Pyraliden stellen heute daß daß es bereits wurde. Eine amerikanischen ebenfalls ausgeschlossen werden
|
2022-09-14T16:17:15.494Z
|
25,474,095 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1099/ijsem.0.001479",
"MAG": "2520215164",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://doi.org/10.1099/ijsem.0.001479"
}
|
Two gamma- and UV-radiation-resistant, pink-coloured bacterial strains, designated YIM F302T and YIM F235, were isolated from the desert of Yanbu' al Bahr located in west of Saudi Arabia. Taxonomic positions of the two isolates were investigated by polyphasic taxonomic approaches. Cells of the two strains were Gram-stain-negative, aerobic and rod-shaped. They were able to grow at 15-45 °C and pH 6.0-8.0 and had a NaCl tolerance limit of 1 % (w/v). Phylogenetic analyses based on 16S rRNA gene sequences revealed that strains YIM F302T and YIM F235 represent members of the genus Deinococcus, sharing highest sequence similarities of 98.3 and 98.4 %, respectively, with Deinococcus grandis DSM 3963T. The strains were found to contain MK-8 as the respiratory menaquinone. Major fatty acids (>10 %) of the two strains were C15 : 1ω6c, C16 : 0 and C16 : 1ω7c. DNA-DNA hybridization values of the two isolates against the closely related type strains were significantly below the 70 % limit for species delineation. Genomic DNA G+C contents of strains YIM F302T and YIM F235 were 69.3 and 69.0 mol%, respectively. Based on the phenotypic and genotypic characteristics recorded, it is determined that the two isolates represent a novel species of the genus Deinococcus, for which the name Deinococcus saudiensis sp. nov. is proposed. The type strain is YIM F302T (=CGMCC 1.15089T=DSM 29933T).
|
2022-12-20T01:10:08.031Z
|
154,073,441 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5282/UBM/EPUB.21832",
"MAG": "1907529560",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We take a first pass at quantifying the magnitudes of debt relief achieved through default and restructuring in two distinct samples: 1979-2010, focusing on credit events in emerging markets, and 1920-1939, documenting the official debt hangover in advanced economies that was created by World War I and its aftermath. We examine the economic performance of debtor countries during and after these overhang episodes, by tracing the evolution of real per capita GDP (levels and growth rates); sovereign credit ratings; debt servicing burdens relative to GDP, fiscal revenues, and exports; as well as the level of government debt (external and total). Across 45 crisis episodes for which data is available we find that debt relief averaged 21 percent of GDP for advanced economies (1932-1939) and 16 percent of GDP for emerging markets (1979-2010), respectively. The economic landscape after a final debt reduction is characterized by higher income levels and growth, lower debt servicing burdens and lower government debt. Also ratings recover markedly, albeit only in the modern period.
|
2022-12-27T14:51:02.304Z
|
142,943,334 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/JCOM.12101",
"MAG": "1520245741",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This article presents a dual-process model of media entertainment representing 2 psychological appraisal processes, and examines how these processes evoke appreciation or enjoyment as a function of the presence/absence of cognitive conflict. The first process (which characterizes experiences of appreciation) is deliberative and slow, and results from cognitive conflict. The second process (which characterizes experiences of enjoyment) is automatic and fast, and occurs when cognitive conflict is inconsequential. Both appraisal processes result from the same underlying framework of intuitive preferences. 2 studies vary narrative conflict among sets of intuitive moral domains to test dual-process predictions regarding slow/fast response times and the association of the presence/absence of conflict with self-reported experiences of appreciation/enjoyment. Discussion examines theoretical implications for entertainment research.
|
2022-12-30T18:08:47.404Z
|
143,149,773 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/0031322X.2013.779802",
"MAG": "1971266093",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Kevin B. Anderson has published an excellent and timely book under a title, though, that almost seems designed to belittle the importance of the material discussed: far from being marginal to either Marx’s thinking or to the concerns of contemporary social theory, Marx at the Margins is centrally about the dynamics of capitalist modernity, the problems of progress and modernization, the role of colonialism for all of these, as well as the resistance to the latter. The title is somewhat misleading also in a second regard: while Marx’s views of ‘non-Western societies’ and ethnicity (mostly of race, actually) are indeed important in this context, nationalism is discussed in the book mostly under the perspective of resistance to colonialism, not, however, comprehensively in its own right. From 1851 62 Marx worked continuously as the chief European correspondent for the New York Tribune, the most important American newspaper of the period. Since covering European politics, included commenting on colonial and world affairs, Marx was forced to study the existing literature on India, Java, Turkey and Russia, the results of which study are documented in numerous notebooks of excerpts. Anderson’s first chapter looks at Marx’s journalistic work from this period as well as the related notebooks. The second chapter is mostly concerned with the question of whether there was any potential for revolution in Tsarist Russia, and how* in this context*the workers’ movement should relate to the question of Polish statehood and nationalism (there are also a few pages on Chechens and Jews). Different from what the chapter’s title, ‘Russia and Poland: The Relationship of National Emancipation to Revolution’, seems to promise, Marx’s position as presented by Anderson was not at all informed by any notion of ‘national emancipation’ but, in strikingly realist terms, reflected a power-political concern with the central role of the Russian regime in the reactionary alliance that defeated the 1848 9 revolutions and determined their aftermath. One of the most interesting aspects here is how Marx reflected on the question of whether the emancipation of the serfs in 1861, which also implied the dissolution of the traditional village community, changed the prospects of revolution in Russia. Patterns of Prejudice, 2013 Vol. 47, No. 2, 184 196
|
2022-02-09T07:39:36.891Z
|
2,385,539 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/00000433-199609000-00006",
"MAG": "1979163940",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Coroner is an ancient office, dating back centuries in England; originally financial officers, coroners over time become medicolegal investigators. Coroners in early Massachusetts functioned under English common law and, later, under statute. However, studies of early coroners and inquests are not common, and many details of how coroners actually functioned are unknown. A previously unpublished set of 19th-century Massachusetts inquest records discloses details of coroner function, including administrative and financial details, social conditions surrounding inquests, and increasing use of medical and toxicologic testimony.
|
2022-02-13T13:35:51.433Z
|
110,277,798 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/APMC.1997.659291",
"MAG": "2114927073",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This work solves the problem of wave propagation in helical line externally loaded by azimuthally magnetized hollow ferrite cylinder. Computed dispersion curves are given. Attention is drawn to non-symmetric modes-as yet absent in the literature-since among them are the lowest order ones. The helical line, located on the inner surface of the ferrite cylinder is simulated by a non-reciprocal conductive cylinder ("sheath helix"). The electromagnetic field components inside the ferrite medium are expressed by special functions of the first and second kinds given by power developments and asymptotic expansions. For sufficiently thick ferrite cylinders the fields are essentially confined within the structure. The method allows analysis and design of non reciprocal phase shifters.
|
2022-06-22T04:04:34.417Z
|
16,654,632 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/EUROSIME.2014.6813801",
"MAG": "2540011543",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In recent years, there has been a dramatic proliferation of research concerned with electronic products because of more various functions are integrate into the device and product's size has become smaller. As a result of these functional requirements, through silicon via (TSV) was investigated, this are getting considerable attentions not only from reducing the packaging size but also from shortening the interconnection's distance that can achieve the effect of enhancing signal transmission. TSVs are the vertical hole through the stacked IC, and they are also responsible for transferring signals between the ICs. Thus, they can improve the time delay of the signal transduction and allow better electrical performance than stacked ICs with wire bonding technology. However, a review of the literature indicates that electronic components will be affected easily by environmental factors such as humidity, pressure, and temperature. In general, the stacked ICs with TSV structure is easily affected by temperature changes than others factors since each material have different thermal expansion. In very recently, the stacked IC packaging has been primarily concerned with thermo-mechanical loadings than traditional single IC packaging, which leads some problems such as via cracking, die cracking and interfacial delamination and so on. The above problems not only affect the performance of the device but also lead the device fail. Hence, most of the studies [1-9] are focus on discussing thermal mechanical loading with simulation method. Some of them discuss the relationship between the TSV shape and the stresses [4, 5]. In addition, most of people just build local TSV structure to do their research [4-9]. Although it can save more time but it also increase the error percentage with real situation. And this paper build the three dimensional four layers stacked IC packaging model from Hsieh [1]'s paper which can more close to real situation. And setting the structure to be simulated from the temperature 150°C to -50°C which is as retreat temperature. This paper use ANSYS software which is based on finite element theory in order to reduce time used and save cost, as finite element simulation can provide results more quickly and cheaply than experiments. Moreover, the research mainly analyzes the maximum von-Mises stress in TSVs and micro-bumps. Besides, this paper will sort out geometries and material properties of underfill which will serious affect von-Mises stress value by Design of Experiments (DoE) analysis. Through the DoE analysis, the critical factors are selected as main design factors to reduce the von-Mises stresses. This study can provide the significant information to effectively design the products and increase the reliability. This information can also eliminate the testing time.
|
2022-09-10T03:06:33.724Z
|
110,949,021 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/MVT.2010.936656",
"MAG": "2067931093",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
TeliaSonera has launched the first fourth-generation (4G) services commercially to customers in Stockholm, Sweden, and Oslo, Norway. TeliaSonera's current 4G networks cover the central city areas of Stockholm and Oslo. The Stockholm 4G city network is supplied by Ericsson, and the Oslo 4G city network is supplied by Huawei. The modems at launch come from Samsung. The 4G network roll-out will continue to Sweden's 25 largest municipalities and recreation areas and to Norway's four largest municipalities.
|
2022-09-11T15:43:18.641Z
|
45,114,034 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1212/01.wnl.0000203118.89092.0f",
"MAG": "2017776368",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Two articles in this issue of Neurology address the problem of predicting vasospasm after aneurysmal subarachnoid hemorrhage (SAH).1,2 Ischemic brain damage from cerebral vasospasm is a major cause of cognitive and motor deficits after SAH. There is angiographic evidence of vasospasm in two-thirds of cases of SAH, half of which become symptomatic typically 4 to 14 days after the bleeding. When symptoms are focal, recognition of vasospasm as the cause is straightforward. However, vasospasm is often diffuse and only manifested by depressed alertness. In these instances, differentiation of vasospasm from other common complications of SAH (such as hydrocephalus, infection, cerebral edema, aneurysmal rebleeding, and hyponatremia) may be difficult.
The pathophysiology of vasospasm is complex and incompletely elucidated. The presence of oxyhemoglobin in the subarachnoid cisterns seems to be the key promoter of the phenomena that ultimately cause narrowing of the arterial lumen and impaired autoregulation.3 The vascular changes are typically reversible, but when severe, they may cause cerebral infarction. The amount of blood in the subarachnoid space on the initial brain CT scan, young age, and history of smoking are risk factors for vasospasm, but their predictive value is limited. Research on vasospasm has been hampered by lack of …
|
2022-09-14T13:35:45.807Z
|
226,201,951 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1136/medethics-2020-106710",
"MAG": "3096506747",
"PubMedCentral": "7607518"
},
"license": null,
"status": "BRONZE",
"url": "https://jme.bmj.com/content/medethics/47/1/16.full.pdf"
}
|
As a result of the COVID-19 global pandemic, paramedics in the UK face unprecedented challenges in the care of acutely unwell patients and their family members. This article will describe and discuss a new ethical dilemma faced by clinicians in the out-of-hospital environment during this time, namely the delivery of bad news to family members who are required to remain at home and self-isolate while the critically unwell patient is transported to hospital. I will discuss some failings of current practice and reflect on some of the ethical and practical challenges confronting paramedics in these circumstances. I conclude by making three recommendations: first, that dedicated pastoral outreach teams ought to be set up during pandemics to assist family members of patients transported to hospital; second, I offer a framework for how bad news can be delivered during a lockdown in a less damaging way; and finally, that a new model of bad news delivery more suited for unplanned, time-pressured care should be developed.
|
2022-10-02T16:18:21.982Z
|
9,090,277 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/AIPR.2014.7041916",
"MAG": "2533921042",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We propose a human re-identification algorithm for multi-camera surveillance environment where a unique signature of an individual is learned and tracked in a scene. The video feed from each camera is processed using a motion detector to get locations of all individuals. To compute the human signature, we propose a combination of different descriptors on the detected body such as the Local Binary Pattern Histogram (LBPH) for the local texture and a HSV color-space based descriptor for the color representation. For each camera, a signature computed by these descriptors is assigned to the corresponding individual along with their direction in the scene. Knowledge of the persons direction allows us to make separate identifiers for the front, back, and sides. These signatures are then used to identify individuals as they walk across different areas monitored by different cameras. The challenges involved are the variation of illumination conditions and scale across the cameras. We test our algorithm on a dataset captured with 3 Axis cameras arranged in the UD Vision Lab as well as a subset of the SAIVT dataset and provide results which illustrate the consistency of the labels as well as precision/accuracy scores.
|
2022-12-17T11:30:47.086Z
|
253,045,683 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1145/3517745.3561455",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
Cellular service operators frequently tune the network configuration to optimize coverage, support seamless handovers, minimize channel interference, and improve the service performance experience to the end-users. Tuning such a complicated network is highly challenging because of the many configuration parameters, evolving complexity of cellular networks, and diverse requirements across voice, video, and data applications. Any misconfigurations or even poor settings can significantly negatively impact service quality. In this paper, we propose a new approach Aurora that derives best practices knowledge from exploration of the massive existing configuration in the network and uses conformity-based recommendation with performance-based filtering to improve cellular service. We implemented and evaluated Aurora using data from a very large LTE and 5G cellular service provider. Our operational experience over the last one year highlights the benefits of Aurora and exposes exciting research opportunities and challenges in configuration tuning and performance management.
|
2022-12-14T09:18:12.429Z
|
145,698,563 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.53761/1.1.1.4",
"MAG": "2150981257",
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://ro.uow.edu.au/cgi/viewcontent.cgi?article=1003&context=jutlp"
}
|
In 2003, the Faculty of Health & Behavioural Sciences at our university offered a series of postgraduate research seminars. The series of seminars, selected by a three-person faculty team, received a mixed reaction - some seminars attracted a large proportion of the students whereas others were poorly attended. Thus, it was decided to continue the seminar series in 2004, but to undertake some formative evaluation to determine the students' preferences for the seminar topics. It was important to gain input from as many students as possible, and to allow maximum latitude for responses. It was decided to conduct a two-stage evaluation process: nominal groups with a subset of postgraduate research students; followed by a survey of all students based on the groups. It was apparent from the results of this study that the students' preferences for seminar content were quite dissimilar to those anticipated by academic staff. This study demonstrates the advantages and disadvantages of the nominal group technique in investigating information and skill needs among postgraduate research students.
|
2022-12-30T00:16:57.408Z
|
6,586,247 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1203/00006450-199704001-01556",
"MAG": "1970237393",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://www.nature.com/articles/pr19971715.pdf"
}
|
The presence of hypothalamic-pituitary-adrenal insufficiency in preterm infants may lead to cardiovascular collapse, respiratory distress syndrome and chronic lung disease. This study was to examine 1). whether prenatal steroid therapy (PS) affect the cortisol response to ACTH stimulation at day 1 (D1) and 7 (D7), 2). whether the response at first day (D1-C) is different from that at 7th day (D7-C), 3). the relationship between the responses and CLD. Definition of CLD was made when infants required oxygen supplementation by 28d of life. Preterm infants with birth weight less than 2 kg and had clinical and radiological evidence of RDS were enrolled. Baseline cortisol concentrations(B) were determined within 12 hrs of life, then 36 μg/kg of ACTH was administered intravenously and serum cortisol concentrations (C-60) were determined 60 min. later. The difference (C-Dif) between C-60 and B was calculated. The procedure was repeated at age 7th day. There were 21 infants enrolled. Age of entry was 8.1 + 2.9 h, mean birth weight was 1364 + 359 g and mean gestational age was 30.7 + 2.6 wks. We conclude that prental administration of steroid did not affect the adrenal response to ACTH stimulation in preterm infants within 7 days of life. There was poor relationship between the cortisol response to ACTH at D1 or D7 and the development CLD in preterm infants. (m + SD) Table
|
2022-01-27T05:23:18.927Z
|
197,606,596 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.17122/NTJ-OIL-2019-1-57-72",
"MAG": "2921793589",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Background According to statistical studies of the causes of failures and destruction of main gas pipelines, metal corrosion and the formation of its products are the main complications that significantly reduce the service life of this important type of oil and gas equipment. At present, it is impossible to conduct in-line diagnostics on more than 2,000 km of gas pipelines of Gazprom Transgaz Ufa LLC due to the lack of equal pass areas, inspection shells of small diameter and stationary cameras for receiving and launching diagnostic devices. The diagnostic methods used in these conditions (electrometric, magnetometric, shuggy examination) do not allow the development of underfilm corrosion to be detected, which often leads to erroneous conclusions about the corrosion situation in the gas pipeline section and its technical condition. Aims and Objectives The aim of the work was to assess the influence of various factors (size of corrosion damage, magnitude of cathode polarization current, depth of location of a corrosion defect, etc.) on hydrogen emission under a protective coating of a gas pipeline. In this case, the main task of the study was to determine the influence of the density of cathode current supplied to the protected gas pipeline and the corrosion rate of steel under insulation flowing with cathodic depolarization on the intensity of hydrogen emission above the ground in the area of the film corrosion. Methods Standard research methods were used: measuring the pH of model corrosive media imitating a ground electrolyte, as well as differences in electrode potentials in different parts of the metal surface under insulation. To determine the corrosion rate of specimens from St3, the bulk test method was used. An original method was also used, which made it possible to assess the presence of a corrosive process under the film by means of registering the hydrogen emission released during hydrogen depolarization. Results It is shown that the proposed method provides a fundamental possibility of registering the hydrogen emission over a corrosion defect. The influence of factors contributing to hydrogen depolarization under a protective coating on the emission intensity has been revealed. The test results allowed to calculate the maximum hydrogen concentration above the corrosion center.
|
2022-02-08T06:32:06.703Z
|
238,256,393 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.29271/jcpsp.2021.10.1257",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://www.jcpsp.pk/oas/mpdf/generate_pdf.php?string=Uk9HTmFrNTZKbzdqS1FCUlZlWmhVZz09"
}
|
Null.
|
2022-02-07T20:34:45.789Z
|
227,541,984 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3760/CMA.J.ISSN.1007-1245.2012.13.056",
"MAG": "3031394441",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Objective To understand the plasma of patients with N terminal pro brain natfiuretic peptide ( NTproBNP ) level in patients with chronic heart failure (CHF) and explore the effect on nursing intervention on these patients.Methods The serum NT-proBNP level 150 patients with CHF and 140 cases of control group were determined.The 150CHF patients were randomly divided into intervention group and control group.Control group wns given routine treatment and nursing care during hospitalization.Basing on control group's treatment,intervention group were given nursing intervention.The Minnesota quality of life scale ( MHL score) was used to evaluate the life quality of all patients in both groups before and after treatment.Results The blood NT-proBNP was significantly higher in intervention group than in control group ( P ＜ 0.01) after treatment.Before treatment,there was no difference in life quality between the two groups.However,after treatment,life quality was significantly better in intervention group than in control group.Conclusions Plasma NTproBNP has reference significance for the early determination of the severity of heart failure.Nursing intervention can improve CHF patients' life quality.
Key words:
Heart failure; Amino-terminal pro-brain natriuretic peptide; Nursing intervention; MHL score
|
2022-01-27T19:41:19.727Z
|
209,953,369 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1742-6596/1326/1/012008",
"MAG": "2981830631",
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://doi.org/10.1088/1742-6596/1326/1/012008"
}
|
Electronic states of an electron localized in a cylindrical quantum dot with Kratzer confining potential in the presence of axial electrostatic field are considered. The dependences of the dipole matrix elements on the geometrical parameters and values of the electric field are calculated. Nonlinear optical effects such as second harmonic generation and optical rectification in this structure are studied. The electric field values, at which double resonance condition are satisfied, have been found. Optical rectification and the second harmonic generation coefficients of energy dependence curves are obtained. Specificity of the Kratzer confinement potential profile leads to vanishing of the mean displacement of the electron in intraband transitions. This fact is reflected in the behavior of optical rectification coefficient, which has a deep dip around certain values of the electric field.
|
2022-07-31T12:19:57.877Z
|
98,152,022 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1115/ICNMM2012-73026",
"MAG": "2094501179",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In the present study, the thermal performance of a micro heat spreader based on flow boiling mechanism was evaluated. The heat spreader under study has a foot print area of 15 × 15 mm2 and is composed by 50 channels with width of 100 μm and depth of 500 μm. Experiments were performed for R134a, heat fluxes up to 310 kW/m2 (based on the foot print area), mass velocities from 400 to 1500 kg/m2s, saturation temperatures of approximately 25°C and liquid subcoolings of 5 and 15°C. Heat-sink averaged heat transfer coefficients based on the effective heat transfer area up to 9 kW/m2K were obtained. From the analyses of the experimental results, for a fixed heat-spreader averaged wall superheating, it was found that the dissipated heat flux increases with decreasing the mass velocity and liquid subcooling. Moreover, the trend with varying mass velocity of the difference between the heat spreader averaged superheating for the onset of nucleate boiling (ONB) and the respective value under boiling conditions is not clear, however it seems that its value increases with increasing the liquid subcooling. The wall superheating excess necessary for the onset of nucleate boiling becomes negligible for mass velocities higher than 1000 kg/m2s.Copyright © 2012 by ASME
|
2022-08-29T00:25:33.434Z
|
196,954,623 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/CHIN.199428019",
"MAG": "2953072573",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Characterization by high-resolution transmission electron microscopy of differently pretreated Cu/TiO[sub 2] samples and IR and mass spectroscopic studies of NO-CO interaction on them from room temperature to 473 K are presented. All samples are characterized by Cu particles well dispersed on TiO[sub 2] surface. The adsorption of CO produces an absorption in the 2112-2130 cm[sup [minus]1] frequency range; the intensity and position of the band strongly depends on the sample pretreatment, and it is strongly affected by NO interaction. NO dosing on a sample reduced at low temperature (LTR) precovered with CO leads to the formation of some CO[sub 2] but the reaction is not complete after heating at 473 K; on a sample reduced at high temperature (HTR) large amounts of N[sub 2]O and Co[sub 2] are detected already after short contact times at room temperature. By heating at 473 K an almost complete conversion to CO[sub 2] and N[sub 2] is observed. On both LTR and HTR samples neither NO nor isocyanate-adsorbed species are detected. Reaction products are observed if the sample HTR is contacted, after outgassing of a previous interaction mixture without desorption of the oxygen atoms produced in the NO dissociation, with a 1:1 NO-CO mixturemore » or with CO and then with NO. If NO is preadsorbed prior to CO dosing in a second run of the reaction, almost no N[sub 2]O and CO[sub 2] are observed. The experimental data indicate that HTR Cu/TiO[sub 2] is significantly more active than LTR Cu/TiO[sub 2], the activity being related to an easy dissociation of the NO molecules, determined by an electron transfer from reduced titania to antibonding orbitals of the NO. Free reduced copper sites are needed for CO activation, the reaction being to some extent inhibited by NO oxidation of the copper. 20 refs., 9 figs., 1 tab.« less
|
2022-09-08T08:16:28.928Z
|
46,144,420 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICSMC.1989.71421",
"MAG": "2153210952",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Implementation of fully adaptive aiding systems is difficult and expensive, requiring the programming of many variables. Two techniques are proposed for simplifying adaptive aid development by severely limiting the levels and kinds of assistance provided. These simplifying strategies are termed operator tailoring and mission-phase tailoring. Each of these techniques has been used at the US Naval Weapons Center to design a different military system, each of which might be termed a semi-adaptive aiding computer program. The two strategies rely on partitioning the levels and kinds of aiding into a few discrete states, rather than providing a continuum of assistance for all possible conditions. The development approach and advantages, disadvantages, and status of the two techniques and the resulting systems are discussed.<<ETX>>
|
2022-09-12T08:56:57.230Z
|
143,073,774 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/13691830802230455",
"MAG": "1972629466",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
As Burundi has moved from ethnic conflict and political exclusion towards peace, reconciliation and democracy, the role of the diaspora has changed as well. Previously, Hutu exiles saw it as their duty to provide uncensored information on the conflict and to fight for the right to express a multitude of opinions. By exploring changes in Burundian websites, the article shows how some Burundian exiles have recently embraced a position of nation-building. Meanwhile, the democratic reforms do not eliminate the anxieties and doubts of many exiled Burundians. These anxieties find their expression on websites where Burundians from all over the world create communities where they can express the unspeakable and float opinions that would never be acceptable in the political field. The article argues that the ideology of democracy and human rights depends on an exclusion of certain opinions—and that diasporic cyberspace may function as a repository for such surplus opinion where the unspeakable may be aired.
|
2022-09-14T23:20:48.086Z
|
29,405,184 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1089/lap.2015.0106",
"MAG": "2178617307",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
BACKGROUND
Elective cholecystectomy is a high-volume, simple procedure, well suited for the development of a pediatric robotic surgery program. Surgical robot software, by "reversing" the surgeon's hands, simplifies single-site cholecystectomy through a single incision at the umbilicus.
MATERIALS AND METHODS
Data were reviewed on the first nine children who had robotic cholecystectomy, with the Da Vinci® Surgical System (Intuitive Surgical Inc., Sunnyvale, CA) device, at our institution. All cases were performed by a single surgeon, proctored by an experienced robotic general surgeon.
RESULTS
There were 9 patients: the first 4 patients had robotic multiport cholecystectomy, and the last 5 had robotic single-site cholecystectomy. Eight were girls. They were 10-18 years of age (median, 14 years). Diagnoses were biliary dyskinesia (n = 5) and symptomatic cholelithiasis (n = 4). Median body mass index was 24.9 (range, 20.2-43.8) kg/m(2). Median anesthesia time for multiport cholecystectomy was 139 (range, 120-162) minutes; median anesthesia time for single-site cholecystectomy was 169 (range 122-180) minutes. Median console time for multiport cholecystectomy was 47 (range, 44-58) minutes; median console time for single-site cholecystectomy was 69 (range, 66-86) minutes. Eight of the 9 patients went home on the day of surgery, and 1 stayed overnight. Patients were seen at 13-20 days after surgery (median, 14 days). There were no complications. There were no conversions to open surgery and none from single-site to multiport surgery.
CONCLUSIONS
Robotic cholecystectomy is safe and efficacious and is a suitable introductory procedure for pediatric surgeons considering a robotic surgery program. Single-site robotic cholecystectomy is a cosmetically attractive option but takes longer than multiport robotic cholecystectomy.
|
2022-12-17T22:03:27.269Z
|
41,240,775 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/AJH.10387",
"MAG": "2069570335",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The purpose of the study was to examine endothelium‐dependent and ‐independent vasodilation of conduit and resistance vessels in sickle cell anemia (HbSS). We measured the effects of intra‐arterial infusion of methacholine, sodium nitroprusside, and NG‐monomethyl‐L‐arginine (L‐NMMA) on forearm blood flow using venous occlusion plethysmography in eight patients with HbSS and 11 HbAA controls. We assessed vasodilation of the conduit brachial artery using ultrasound in 17 patients with HbSS and 41 nonanemic controls. Forearm blood flow response to methacholine was similar in HbSS and HbAA, while the response to sodium nitroprusside was greater in those with HbSS. Nitric oxide synthase inhibition with L‐NMMA attenuated methacholine‐induced forearm blood flow to a lesser extent in HbSS compared to HbAA, suggesting diminished nitric oxide (NO) contribution to endothelium‐dependent vasodilation. Flow‐mediated and nitroglycerin‐induced dilation were impaired in HbSS compared to controls and were not affected by the antioxidant vitamin C or the precursor substrate for NO synthesis L‐arginine. NO bioactivity is reduced but differs in peripheral conduit and resistance vessels in HbSS. Resistance vessels have preserved response to exogenous NO donors but have diminished contribution of NO to endothelium‐dependent vasodilation. Conduit vessels demonstrate impaired vasodilation to endogenous and exogenous NO. Am. J. Hematol. 74:104–111, 2003. © 2003 Wiley‐Liss, Inc.
|
2022-12-19T05:19:53.065Z
|
2,665,192 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1086/524110",
"MAG": "1989296635",
"PubMedCentral": null
},
"license": "elsevier-specific: oa user license",
"status": "BRONZE",
"url": "http://www.cell.com/article/S0002929707637793/pdf"
}
|
DNA methylation is a heritable modification of genomic DNA central to development, imprinting, transcriptional regulation, chromatin structure, and overall genomic stability. Aberrant DNA methylation of individual genes is a hallmark of cancer and has been shown to play an important role in neurological disorders such as Rett syndrome. Here, we asked whether normal DNA methylation might distinguish individual brain regions. We determined the quantitative DNA methylation levels of 1,505 CpG sites representing 807 genes with diverse functions, including proliferation and differentiation, previously shown to be implicated in human cancer. We initially analyzed 76 brain samples representing cerebral cortex (n=35), cerebellum (n=34), and pons (n=7), along with liver samples (n=3) from 43 individuals. Unsupervised hierarchical analysis showed clustering of 33 of 35 cerebra distinct from the clustering of 33 of 34 cerebella, 7 of 7 pons, and all 3 livers. By use of comparative marker selection and permutation testing, 156 loci representing 118 genes showed statistically significant differences--a >or=17% absolute change in DNA methylation (P<.004)--among brain regions. These results were validated for all six genes tested in a replicate set of 57 samples. Our data suggest that DNA methylation signatures distinguish brain regions and may help account for region-specific functional specialization.
|
2022-12-19T20:12:33.900Z
|
30,318,929 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1103/PHYSREVE.85.016603",
"MAG": "2333276405",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We derive analytical rogue wave solutions of variable-coefficient higher-order nonlinear Schrödinger equations describing the femtosecond pulse propagation via a transformation connected with the constant-coefficient Hirota equation. Then we discuss the propagation behaviors of controllable rogue waves, including recurrence, annihilation, and sustainment in a periodic distributed fiber system and an exponential dispersion decreasing fiber. Finally, we investigate nonlinear tunneling effects for rogue waves.
|
2022-12-22T02:15:33.105Z
|
241,200,170 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.36012/pmr.v2i2.1827",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "http://encyclopub.com/pmr/article/download/1827/1709"
}
|
去甲斑蝥素来源于天然中药——斑蝥，由中国学者发现并应用于临床，但是存在 泌尿系统、肝毒性等问题。因此，笔者综述了斑蝥素的现代药理作用，以期为进一步研究斑 蝥素及其衍生物抗肿瘤机制提供参考。
|
2022-01-24T18:30:18.562Z
|
248,488,006 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.47191/ijcsrr/v5-i4-59",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.valmet.com/globalassets/media/downloads/white-papers/process-improvements-and-parts/wpp_nondestructivetesting.pdf"
}
|
The field of NDT is a very broad, interdisciplinary field that plays a critical role in evaluating the structural component and systems perform their function in a reliable manner. A review is presented of Non-Destructive testing methods for evaluating material characteristics, deformation in the materials without destroying the material. These testing methods are very important in determining and identifying the discontinuity and defects found on a material and parts of an object. There have been various NDT methods built upon different principles for Quality Assurance during the whole lifecycle of the product. Methods like Visual Inspection, Radiographic method, Optical techniques, Wave-based methods, etc. are used to analyze the defects on material and part of it. The Non-Destructive testing method has been widely used in different fields like in manufacturing, medical devices, packaging, marine industries, waste management, etc., but especially used in oil and gas industries, aircraft, and nuclear power plants. This paper reviews these NDT techniques and compares them in terms of intrinsic characteristics and their applications.
|
2022-05-10T00:48:12.097Z
|
181,834,020 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.11628/KSPPE.2019.22.1.075",
"MAG": "2946466945",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This study aimed to examine the current status of mobile applications for garden design and extract valuable contents for the development of garden design programs for future reference. Mobile applications released in Korean or English on Google Play App Market as of July, 2018 were analyzed in this study (1 application in Korea and 14 applications overseas). The purposes of this study are to analyze the components of the programs for those who actually intend to create a garden and to use it as a resource for developing mobile applications for garden design. Thus, program components and contents were analyzed for garden design applications based on real space (1 application in Korea and 3 applications overseas) that could actually help users. The analysis of mobile applications for garden design shows that while overseas garden programs are rapidly developing in various fields, the number of garden design mobile applications developed in Korea and the amount of information platforms are significantly insufficient. This study suggested flowchart for garden design mobile applications based on the analysis results of existing garden design application. This flowchart includes a series of processes from planning/designing gardens to purchasing plants and facilities to constructing/maintaining gardens for users who intend to design and create a real garden. Furthermore, this study proposed a freemium business model based on 4R(Reflex, Reality, Real place, Real communication) marketing strategies for mobile applications. Realistic experiences can be increased through graphics and information about gardens and plants provided in this study, and location-based information services as well as the creation of systems connected with vendors and suppliers of products related to gardens can induce consumers’ purchasing behaviors. Additionally PR activities through various garden-related cultural events are expected to attract more users.
|
2022-07-01T02:12:33.871Z
|
10,813,539 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/13554790802680305",
"MAG": "2070188053",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
There are several group and case studies that investigate developmental dyslexia in children, and acquired and developmental reading disabilities in adults. To date however, there are few detailed investigations on cases of early acquired dyslexia. The purpose of this study was to examine such a case (participant referred to as SP). The goals of this investigation were to compare SP's reading impairments to the major subtypes of dyslexia, establish SP's specific reading deficits, and consider the neuropsychological variables that may impact on SP's reading disability.
|
2022-07-01T03:53:00.235Z
|
34,380,412 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1213/ANE.0000000000000324",
"MAG": "2324086275",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Informed consent discussions, performance measurement, and studies of patient outcomes all require accurate information regarding the likelihood of a good or bad outcome after surgery for an individual patient. Statistical risk models, typically based on multivariate analyses of retrospective data, aim to help clinicians quantify the probability of adverse outcomes for individual patients. Beginning with Lee Goldman et al.’s 1977 landmark publication of a multivariate risk index for postoperative cardiac events,1 statistical risk models have been used for more than three decades in various surgical contexts prospectively to predict the likelihood of adverse outcomes for patients considering surgical interventions.2 Predictions derived from such models can then be used to help decide whether to have surgery (e.g., medical versus surgical management of hip fracture), what kind of surgery to have (e.g., conventional versus transcatheter aortic valve replacement), or where to have surgery (e.g., outpatient surgicenter versus hospital).
In predicting risk before surgery, one size does not necessarily fit all, different risk factors might be more or less important for different groups of patients. Perhaps for this reason, different approaches to predicting risk have emerged that are specific to certain surgical specialties and specific procedures. For example, the Society of Thoracic Surgeons (STS) risk score is used to predict operative mortality for patients undergoing cardiothoracic surgery.3 In addition to being a helpful research tool for comparing patient populations, the STS score has emerged as a decision point in determining the management approach for symptomatic aortic stenosis. For instance, in the PARTNER trial, an STS score of ≥10% was used to define a high-risk surgical group.4 Only those patients at or above this cutoff were considered for transcatheter aortic valve replacement. Other surgical specialties employing procedure-specific risk models include orthopedics,5 and transplant surgery.6
In this issue of Anesthesia & Analgesia, Reponen and colleagues review evidence on preoperative risk stratification for patients undergoing cranial neurosurgery.7 The authors compared commonly used risk scores by conducting a qualitative systematic review. From a starting sample of more than 2000 papers, Reponen et al. analyzed 25 published reports describing outcomes after craniotomy as a function of five different scales: American Society of Anesthesiologists Physical Status classification (ASA; 10 studies), the Karnofsky Performance Score (KPS; 16 studies), the Charlson Comorbidity Score (CCS; 3 studies), the modified Rankin Scale (mRS; 2 studies), and the Sex, KPS, ASA classification, meningioma Location, and peritumoral Edema score (SKALE; 2 studies). The authors found evidence of some association among three of these scores and postoperative outcomes: ASA physical status was associated with mortality and with infectious complications including surgical site infection and postoperative meningitis. The KPS was associated with mortality, functional impairment and systemic complications, including pneumonia, heart failure, and deep venous thrombosis. The CCS was associated with mortality in patients who had elective treatment of intracranial aneurysms and in elderly patients with intracranial tumors.7 As Reponen and colleagues note, important differences in study design, patient populations, and outcome definitions across studies limit the conclusions that can be drawn from this review. The 25 studies they reviewed included retrospective and prospective designs, sample sizes ranging from 30 to almost 5000 patients, and varying definitions of operative and non-operative complications. Indeed, the authors note that they were unable to perform a quantitative meta-analysis (as opposed to a narrative review) because of marked differences in the methods and outcomes used across studies.
The work of Reponen and colleagues offers a useful starting place for further research and discussion regarding prediction of outcomes after surgery. Importantly, it highlights the importance of critically examining the individual variables contained within any risk model; ideally, a plausible physiologic mechanism should link the individual elements of a risk score to the outcome of interest. In terms of postoperative mortality, for example, increasing age and comorbidity burden might predict increased mortality. In other cases, the relationship may be less apparent. For example, the data suggest that patients with a higher ASA physical status classification may be more likely to experience postoperative infections. While this association may be supported by observations in the data, further research is likely to be required to tease out the specific mechanisms that link poor physical status to infectious outcomes and to develop effective interventions to decrease risk among future patients.
Reponen et al.’s review also highlights challenges in incorporating variables into risk scores that rely on individual clinician judgment. Indeed, the Goldman Index, and statistical risk modeling as a whole, grew out of a concern that existing tools for patient assessment, such as the ASA physical status classification, were prone to subjectivity due to their reliance on individual clinician’s judgments. Yet when it has been included in statistical risk models, the ASA physical status classification turns out to be a tremendously useful predictor of postoperative outcomes specifically because it takes advantage of physicians’ abilities to judge how sick an individual patient is, above and beyond the comorbidities that appear in a patient’s chart. For example, a recent review of heterogeneous patient populations found that, despite poor interrater reliability, ASA physical status was an accurate predictor of postsurgical mortality.8 Nonetheless, reliance on human judgment in scoring patient risk raises important concerns regarding the potential for risk assessments, such as the ASA physical status classification, to vary across raters and to be overly influenced by individual biases.
Of the five scores that Reponen and colleagues reviewed, four had components that require some degree of judgment on the part of the assessing clinician. As such, the paper highlights opportunities for further research on opportunities to increase the reliability of such assessments across clinicians and settings, and how such clinical assessments can potentially be incorporated into large-scale prospective data collection efforts. Such efforts are ongoing outside of anesthesia through the Veterans Affairs and American College of Surgeons’ National Surgical Quality Improvement Programs (NSQIP9 and ACS-NSQIP10 and within anesthesiology through the Anesthesia Quality Institute’s National Anesthesia Clinical Outcomes Registry,11 and the University of Michigan’s Multicenter Perioperative Outcomes Group.12 Ultimately, data from these and other registries may carry potential not only for the development of additional risk prediction models for neurosurgery and other specialties, but also shed light on how the collection and data on specific risk predictors can be more effectively standardized going forward.
The work of Reponen et al. make it clear that further work is needed to develop reliable and robust approaches to predicting risk for neurosurgical patients. In the meantime, however, there are patients and clinicians who need guidance as they consider therapeutic options. For patients and clinicians, the work of Reponen et al confirms that that worst functional status and greater degrees of comorbidity are likely to be associated with perioperative morbidity and mortality in craniotomy patients,7 and that further work is still needed to identify the specific combinations of factors that most accurately predict poor outcomes. In the meantime, then, perhaps we should consider the risk scores reviewed by Reponen and colleagues to be places to start in our conversations about operative risk among neurosurgical patients, but not the ultimate arbiters of therapeutic choices.
|
2022-08-31T21:36:55.555Z
|
212,913,505 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.7546/nifs.2019.25.3.53-70",
"MAG": "2998299344",
"PubMedCentral": null
},
"license": "CCBYSA",
"status": "GOLD",
"url": "http://ifigenia.org/images/9/90/NIFS-25-3-53-70.pdf"
}
|
: The concept of intuitionistic fuzzy sets of second type (IFSST) generalizes intuitionistic fuzzy sets (IFS) and thus, has many applications in decision making problems. The main feature of IFSST is that it is characterized by three parameters, namely: membership degree, non-membership degree and degree of indeterminacy in such a way that the sum of the square of each of the parameters is one. The purpose of this paper is to present the axiomatic definition of distance between IFSST, taking into account the three parameters that describe the sets and to investigate numerically, the validity of some distances between intuitionistic fuzzy sets introduced by E. Szmidt and J. Kacprzyk in IFSST environment. Finally, we explore the application of IFSST in diagnostic medicine by employing normalized Hamming distance of IFSST to calculate the distance between patients and diseases, because it provides a reliable distance with respect to other distances. Actually, by using the distance between patients and diseases (both in IFSST values), with recourse to the corresponding symptoms observe in the patients and of the diseases, we determine the illness of the paients. These distances are suggestible to be deployed in solving multicriteria decision making problems.
|
2022-09-07T11:33:27.683Z
|
182,618,848 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/0966369X.2019.1609430",
"MAG": "2946741691",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract Our key aim with this collection, a combination of original empirical contributions and interventions by experts from across social geography and sociology, is to consolidate and advance feminist, interdisciplinary approaches to the everyday geographies of family via contemporary, empirically grounded research and direct interdisciplinary exchanges. This themed section showcases cutting edge geographical work in relation to the everyday geographies of family life; highlights the diversity of work being done within feminist geography and; develops a feminist geography that is enriched through engagement with interdisciplinary intellectual exchanges. We describe the intervention section that follows this introductory piece, bringing together writing from across sociology and geography, where there has been a cross-pollination of ideas around everyday family life, but very little concerted effort to bring these into dialogue to date. In introducing each contributor and their substantive interests, we will draw out relevant theoretical links across papers that illustrate how both family and the everyday, as key concepts, are being unsettled and problematised. Contributors to the intervention section are notable scholars that have set and shaped key agendas and debates. In their shorter papers, they will reflect on their influence on developing debates about family and everyday life. Drawing links across this suite of themed and intervention papers, it will be argued that interdisciplinary work around the family is important for carving out and consolidating feminist, interdisciplinary discussions and for determining what might also be distinctive about feminist approaches to family geographies as debates progress.
|
2022-09-11T15:10:59.354Z
|
99,212,557 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/ACS.JPCC.7B02394",
"MAG": "2607571693",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper presents solid-state ligand exchange of spin-coated colloidal lead sulfide quantum dot (PbS QD) films by methylammonium iodide (MAI) and integration of them in depleted heterojunction solar (DHS) devices having an antireflecting (AR) nanocone plastic structure. Time-resolved photoluminescence measurements determine a shorter lifetime of the charge carries on a semiconductor (TiO2) electron transfer layer for the MAI-passivated QD films as compared with those with long-chain aliphatic or short thiol ligands. Consequently, the DHS device yields improved power conversion efficiency (>125%) relative to oleic-acid-passivated PbS QD films. Using anodized aluminum oxide templates, an inverted nanocone polydimethylsiloxane structure was also prepared and utilized as an AR layer in the DHS device. The solar cells exhibit an energy conversion efficiency of 7.5% with enhanced water-repellant ability.
|
2022-10-11T14:40:10.967Z
|
247,957,300 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3389/fvets.2022.838481",
"MAG": null,
"PubMedCentral": "9020877"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.frontiersin.org/articles/10.3389/fvets.2022.838481/pdf"
}
|
Objective The purpose of this study was 2-fold: to evaluate whether the timing of collection influences the platelet counts and leukocyte counts of PRP samples, and to evaluate growth factor concentrations in canine PRP after freezing and storage without a preservation agent for 6 months of time. Materials and Methods Whole blood collection was performed three times over the course of 4 weeks. All PRP samples were evaluated with a CBC analysis. The PRP samples were frozen and stored without a preservation agent for the duration of the 4-week study. Results The platelet and leukocyte counts were not statistically significant between the timing of blood draws over the course of 4 weeks. All three growth factors were present in measurable quantities after freezing and storage for 6 months without a preservation agent. Clinical Relevance PDGF, TGF-β1, and VEGF were all present in measurable quantities. Furthermore, PDGF and TGF-β1 were correlated with platelet count of the final PRP. VEGF concentrations were able to be quantified. We correctly hypothesized growth factor concentrations would be present and measurable in canine PRP frozen and stored without a preservation agent for 6 months.
|
2022-04-30T12:20:45.013Z
|
229,162,575 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3389/fmicb.2020.598010",
"MAG": "3187277737",
"PubMedCentral": "7769777"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.frontiersin.org/articles/10.3389/fmicb.2020.598010/pdf"
}
|
Sepsis is a life-threatening organ dysfunction condition caused by a dysregulated host response to infection and lack of effective treatment method. Supplementation of probiotics has emerged as a potential biotherapy for inflammatory diseases in recent years, but its role in protecting viscera against the damage caused by sepsis and the underlying mechanism is poorly understood. Streptococcus thermophilus 19 is one of the most well-studied probiotics, which is selected in this study among seven strains isolated from homemade yogurt due to its optimal ability of suppressing the inflammation response in vitro. It showed significant decrease in the expression of TNF-α, IL-1β, and IL-6 in the co-culture of S. thermophilus 19 and LPS-treated mouse macrophage. The effect of S. thermophilus 19 in mice and the response of mice gut microbiota were subsequently investigated. In LPS-induced septic mouse model, S. thermophilus 19 was highly resistant to LPS and exhibited significantly decreased expressions of inflammatory factors compared to LPS-treated mice. A MiSeq-based 16S rDNA sequence analysis revealed that the decrease of gut microbial diversity in mice intraperitoneally injected with 1 mg/ml LPS were mitigated by the administration of S. thermophilus 19. Fusobacterium significantly decreased during the development of sepsis and rose again after supplement strain 19, while Flavonifractor showed the opposite trend, which demonstrated these two genera were the key bacteria that may function in the mice gut microbiota for alleviation of LPS-induced inflammation reaction. To conclude, S. thermophilus 19 may be a potential candidate for novel biotherapeutic interventions against inflammation caused by sepsis.
|
2022-12-07T22:32:11.971Z
|
252,561,918 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2118/210336-ms",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
One of the significant unconventional oil reserves in the USA is the Bakken Petroleum System located in the Williston Basin. It is known for its complex lithology, composed of three prominent members, Upper and Lower Bakken, with similar properties of organic-rich shale relatively uniform compared to the middle member with five distinct lithofacies, formed mainly from calcite, dolomite, or silica. The higher properties variability makes the reservoir characterization more challenging with low permeability and porosity. Understanding lithology by quantifying mineralogy is crucial for accurate geological modeling and reservoir simulation. Besides that, the reservoir’s capacity and the oil production are affected by the type and the mineral volume fractions, which impact the reservoir properties. Conventionally, to identify the mineralogy of the reservoir, the laboratory analysis (X-Ray Diffraction, XRD) using core samples combined with the well logs interpretation is widely used. The unavailability of the core data due to the high cost, as well as the discontinuities of the core section of the reservoir due to the coring failures and the destructive operations, are one of the challenges for an accurate mineralogy quantification. The XRD cores analysis is usually used to calibrate the petrophysical evaluation using well logs data because they are economically efficient. To remedy to these limitations, artificial intelligence and data-driven based models have been widely deployed in the oil and gas industry, particularly for petrophysical evaluation. This study aims to develop machine learning models to identify mineralogy by applying six different machine learning methods and using real field data from the upper, middle, and lower members of the Bakken Formation. Efficient pre-processing tools are applied before training the models to eliminate the XRD data outliers due to the formation complexity. The algorithms are based on well logs as inputs such as Gamma Ray, bulk density, neutron porosity, resistivity, and photoelectric factor for seven (07) wells. XRD mineral components for 117 samples are considered outputs (Clays, Dolomite, Calcite, Quartz, and other minerals). The results' validation is based on comparing the XRD Data prediction from the developed models and the petrophysical interpretation. The applied approach and the developed models have proved their effectiveness in predicting the XRD from the Bakken Petroleum system. The Random Forest Regressor delivered the best performance with a correlation coefficient of 78 percent. The rest of the algorithms had R-scores between 36 and 72 percent, with the linear regression having the lowest coefficient. The reason is the non-linearity between the inputs and outputs.
|
2022-12-14T00:54:02.710Z
|
85,568,350 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/13880200801968904",
"MAG": "2118415164",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://www.tandfonline.com/doi/pdf/10.1080/13880200801968904?needAccess=true"
}
|
Abstract The antiprotozoal activity of 26 ethanol extracts derived from 13 species of the genus Bomarea (Alstroemeriaceae) were evaluated against the promastigote forms of three Leishmania species (L. amazonensis L., L. braziliensis Vianna, and L. donovani Laveran & Mesnil) and the epimastigote form of Trypanosoma cruzi Chagas. IC50 values for leishmanicidal activities were between 4.9 and 98.6 μ g/mL, B. setacea extracts being the most active against the three species of Leishmania. Amphotericin B (IC50 = 0.2 μ g/mL) and pentamidine (IC50 = 10 μ g/mL) were used as control in this assay. IC50 values for antitrypanosomal activities were between 65.2 and 92.7 μ g/mL, whereas the control benznidazole had an IC50 value of 2 μ g/mL.
|
2022-12-16T15:51:31.349Z
|
28,781,388 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1447-0756.1999.tb01177.x",
"MAG": "2122643637",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Objective(s): To elucidate the relationship between intracellular H2O2 production and embryo development in different oxygen culture conditions.
|
2022-12-16T14:26:15.522Z
|
100,857,642 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1039/C5RA22993F",
"MAG": "2266518427",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Polymeric BODIPY derivatives with reactive functional groups undergo reversible formation of covalent bonds leading to self-healing properties. Cross-reactivity of acyl-hydrazine and aldehyde moieties forms the basis of dynamic covalent chemistry leading to sol–gel transition in this series of compounds. In addition, thin layers of absorbers show efficient energy transfer indicating a potential in solar concentration.
|
2022-12-18T01:18:57.677Z
|
160,827,753 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.30861/9781407306339",
"MAG": "3015480862",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This volume provides a compilation of Sarmatian and Sauromation finds from the area north and northeast of the Caspian sea, making available a wealth of often fragmentary research previously only available in Soviet/Russian journals and monographs. It also surveys the topography of the region, describes the history of research on the subject, and provides an up-to-date discussion of dating and chronology. German text.
|
2022-01-27T11:40:54.386Z
|
153,625,517 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1976-5118.2005.TB00310.X",
"MAG": "2021214776",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This article describes the U.S.-China relations and its impact on the Korean Peninsula. It outlines the key motivations behind the making of Chinese foreign policy and then reports on the current stability and uncertainties between Beijing and Washington. As a result of its overall objectives in diplomacy, Beijing is seeking a shared strategic interest with the United States on the Korean issue.
The PRC prefers the continued survival of the DPRK regime and develops ever-closer relations with the ROK; its basic policy towards the Korean Peninsula remains pro-status quo and anti-nuclearization. However, the uncertainties and complications of the Sino-American relations profoundly affect China's strategic calculation about Korean Peninsula and indicate changes and problems in the Chinese Korea policy.
|
2022-02-09T02:14:32.395Z
|
41,188,181 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/00003086-200302000-00008",
"MAG": "2068170154",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The current author offers an anecdotal history of the total joint replacement industry in North America that emerged in the 1960s and of the individuals and organizations that shaped it. The author's career as an arthroplasty pioneer, influences that helped him become interested in uncemented fixation techniques, and his impression of the requirements the industry places on emerging orthopaedic leaders also are chronicled.
|
2022-02-12T03:56:07.461Z
|
60,477,573 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/TENCON.2003.1273390",
"MAG": "1518990501",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Segmentation and transcription of a speech corpus is a prerequisite in the development of an automatic speech recognition (ASR) system. In this paper, we develop a method for automatically segmenting and transcribing the Filipino speech corpus that is being developed at the DSP laboratory. A multi-layer perceptron (MLP) will take speech feature inputs, multiply them by weights computed from a training set of labeled speech. The system is based on a multi-layer perceptron and start synchronous decoder. The corpus was divided into three subcorpora, the paragraphs and sentences sub-corpus (par+sen), the words sub-corpus and the syllables sub-corpus. For the par+sen sub-corpus, we obtained a 62.64% phoneme recognition rate with 75.68% of labels within 20 ms of hand-labeled transcriptions; for the words-subcorpus, 63.93% phoneme recognition rate with 72/38% within 20 ms of hand-labeled transcriptions; and for the syllables sub-corpus, 72.60% phoneme recognition rate with 75.69% within 20 ms of hand-labeled transcriptions.
|
2022-04-10T17:46:08.999Z
|
220,285,835 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1503/cmaj.050097",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://www.cmaj.ca/content/cmaj/172/4/598.full.pdf"
}
|
Dr. Marc Baltzan, a pioneer in kidney transplantation in Canada and a leader for the profession, died Jan. 1, 2005. He was 75. He was the first president of the Saskatchewan Medical Association (1967) and later became president of the CMA (1982–3). During his tenure as CMA president, he locked horns with federal health minister Monique Bégin over the creation of the Canada Health Act. He wrote that hospitals are being underfunded and the proposed act "completely ignores this situation and even attempts to sweep it under an ideological rug: equality will be achieved by equality of denial" (CMAJ 1983;128:736). A graduate of McGill University (1953), Dr. Baltzan specialized in nephrology at Royal University and St. Paul's hospitals in Saskatoon. He was also the chair of the University of Saskatchewan's Department of Medicine. Dr. Baltzan received the Order of Canada in 1995 and the Saskatchewan Order of Merit in 1999. Roy Romanow told the Globe & Mail that Dr. Baltzan was "one of Canada's outstanding Canadians" and "a caregiver in the most beautiful and most expansive meaning of that word." He is survived by his wife, Nahid Ahmad, 4 children and 5 grandchildren.
|
2022-09-30T00:30:00.597Z
|