corpusid
int64 5
255M
| openaccessinfo
dict | abstract
stringlengths 1
10k
| updated
stringlengths 20
24
|
|---|---|---|---|
10,928,574 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1001/JAMA.1992.03490120020005",
"MAG": "2013265536",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
WHILE FINANCING health care adequately is essential, says the recently retired president of Johns Hopkins University's Hospital and Health System, Baltimore, Md, "just putting more money into the system isn't going to change such things as low birth weight, neonatal mortality, uncontrolled hypertension, and other treatable if not curable conditions." What the former executive, Robert Heyssel, MD, says he finds so startling is that Hopkins practices some of the most advanced medicine in the world, "yet up the street we have people dying of hypertension, going blind from cataracts or glaucoma, and on all sides there is evidence of failure to get adequate prenatal and postnatal care. These are things we can do something about, but we haven't done a very good job." A survey among young women in east Baltimore, he says, indicates that financial constraints are not what prevent them from seeking care—most of them are covered by
|
2022-02-13T05:50:03.983Z
|
111,528,447 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2514/6.2012-1294113",
"MAG": "2326339522",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In 2009 an innovative voice intercom system (VIS) was installed at Galileo Control Centre. The constellation currently operated consists of two IOV satellites with two further IOV satellites planned for 2012, and will be expanded to 30 in FOC – operational for some decades. This leads to significant constraints. The VIS needs to be simple to use – since over time a wide variety of operations personnel will have access. The VIS has brought state-of-the-art and proven technology based on voice-over-IP into the space ground-segment. A fully redundant and decentralized architecture solves the single point of failure issue, circumventing entirely the need for any down-time due to maintenance. In addition the hardware is robust and easy to install. It is possible to use the system after a very short training.
|
2022-06-05T02:34:34.021Z
|
231,317,289 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.23960/JTUR.VOL1NO1.2019.15",
"MAG": "2998299028",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Universitas Lampung dengan luas 63,5 hektar masih memiliki permasalahan dalam penanganan sampah. Peningkatan jumlah sampah terjadi seiring dengan bertambahnya jumlah warga kampus Universitas Lampung. Angka laju timbulan dan komposisi sampah belum diketahui secara pasti. Tujuan dari penelitian ini adalah mengkaji timbulan, komposisi dan merencanakan konsep pengelolaan sampah Kampus Universitas Lampung yang terdiri dari lima aspek yang saling mempengaruhi satu sama lainnya yaitu aspek teknik operasional, peraturan, kelembagaan, biaya dan peran serta warga kampus. Pengukuran timbulan sampah menggunakan metode load count analysis dengan sampel yang berasal dari lingkungan kampus Universitas Lampung. Komposisi sampah ditentukan dan dianalisis berdasarkan SNI 19-3964-1994. Hasil penelitian berupa laju timbulan sampah di lingkungan Universitas Lampung sebesar ±770 kg/hari. Komposisi sampah paling besar didominasi oleh sampah yang dapat dikomposkan, plastik, dan kertas.
|
2022-07-10T03:05:53.823Z
|
249,322,069 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1155/2022/5343801",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://downloads.hindawi.com/journals/jmath/2022/5343801.pdf"
}
|
The focus of this research is to use a new extended beta function and develop the extensions of Gauss hypergeometric functions and confluent hypergeometric function formulas that are presumed to be new. Four theorems have also been defined under the generalized fractional integral operators that provide an image formula for the extension of new Gauss hypergeometric functions and the extension of new confluent hypergeometric functions. Moreover, discussed are analogous statements in terms of the Weyl, Riemann–Liouville, Erdélyi–Kober, and Saigo fractional integral and derivative operator types. Here, we are also able to generate more image formulas by keeping some integral transforms on the obtained formulas.
|
2022-09-15T03:21:03.710Z
|
219,753,900 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/en13112696",
"MAG": "3032619433",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/1996-1073/13/11/2696/pdf?version=1591349051"
}
|
This paper presents a prototype of high speed brushless synchronous generators (BSG) design for the application in autonomous electric power generation systems (e.g., airplane power grid). Commonly used salient pole field of the main generator part of BSG was replaced with a prototype non-salient pole field. The main objective of the research is an investigation into the advantages and disadvantages of a cylindrical field of the main generator part of BSG over the original salient pole field. The design process of the prototype generator is presented with a focus on the electromagnetic and mechanical finite element method (FEM) analysis. The measurements of prototype and commercial BSG were conducted for the nominal speed of 8 krpm. The advantages and disadvantages of the proposed solution were established based on measurements in load and no-load conditions.
|
2022-12-02T12:16:17.119Z
|
11,926,548 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1128/IAI.00763-07",
"MAG": "2100597825",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
ABSTRACT Bordetella pertussis and Bordetella parapertussis are closely related endemic human pathogens which cause whooping cough, a disease that is reemerging in human populations. Despite how closely related these pathogens are, their coexistence and the limited efficacy of B. pertussis vaccines against B. parapertussis suggest a lack of cross-protective immunity between the two. We sought to address the ability of infection-induced immunity against one of these pathogens to protect against subsequent infection by the other using a mouse model of infection. Immunity induced by B. parapertussis infection protected against subsequent infections by either species. However, immunity induced by B. pertussis infection prevented subsequent B. pertussis infections but did not protect against B. parapertussis infections. The O antigen of B. parapertussis inhibited binding of antibodies to the bacterial surface and was required for B. parapertussis to colonize mice convalescent from B. pertussis infection. Thus, the O antigen of B. parapertussis confers asymmetrical cross-immunity between the causative agents of whooping cough. We propose that these findings warrant investigation of the relative role of B. parapertussis in the resurgence of whooping cough.
|
2022-12-30T01:11:15.893Z
|
239,616,823 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/vaccines9101088",
"MAG": null,
"PubMedCentral": "8539638"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2076-393X/9/10/1088/pdf?version=1632792834"
}
|
China has initiated the COVID-19 vaccination for children aged 15–17 years since late July 2020. This study aimed to determine the association between adult vaccine hesitancy and parental acceptance of childhood COVID-19 vaccines in a multi-ethnicity area of northwestern China. A web-based investigation was performed with a convenience sampling strategy to recruit the parents aged 20–49 years. In a total of 13,451 valid respondents, 66.1% had received the COVID-19 vaccination, 26.6% were intent to receive, while 7.3% were not intent, with an increasing vaccine hesitancy (p < 0.001). Moreover, vaccination uptake of four common vaccines in their children remained low (29.0% for influenza vaccine, 17.9% for pneumonia vaccine, 10.9% for rotavirus vaccine, 8.0% for Enterovirus-71 vaccine), while overall parental acceptance of childhood COVID-19 vaccines was 50.0% (32.7% for those aged 0–5, 46.6% for 6–10, 73.3% for 11–18; p < 0.001). Vaccination uptake of these four vaccines and parental acceptance of childhood COVID-19 vaccine were negatively associated with adult vaccine hesitancy. In addition, respondents mostly preferred childhood COVID-19 vaccines with weak mild common adverse events (β = 1.993) and no severe adverse events (β = 1.731), demonstrating a positive association with adult vaccine hesitancy. Thus, it warrants specific countermeasures to reduce adult vaccine hesitancy and improve strategies for childhood vaccination.
|
2022-12-31T06:17:37.882Z
|
129,914,353 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1175/1520-0485(1985)015<1378:CAPOTN>2.0.CO;2",
"MAG": "2086661669",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract Four different parameterizations of the nonlinear energy transfer Snl in a surface wave spectrum are in investigated. Two parameterizations are based on a relatively small number of parameters and are useful primarily for application in parametrical or hybrid wave models. In the first parameterization, shape-distortion parameters are introduced to relate the distribution Snl for different values of the peak-enhancement parameter γ. The second parameterization is based on an EOF expansion of a set of Snl computed for a number of different spectral distributions. The remaining two parameterizations represent operator forms that contain the same number of free parameters as used to describe he wave spectrum. Such parameterizations with a matched number of input and output parameters are required for numerical stability in high-resolution discrete spectral models. A cubic, fourth-order diffusion-operator expression derived by a local-interaction expansion is found to be useful for understanding many ...
|
2022-12-31T19:26:37.375Z
|
188,422,675 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4103/jotr.jotr_10_18",
"MAG": "2885959205",
"PubMedCentral": null
},
"license": "CCBYNCSA",
"status": "GOLD",
"url": "https://doi.org/10.4103/jotr.jotr_10_18"
}
|
Background: To compare functional outcome of cemented and uncemented total hip replacement (THR). Materials and Methods: In this hospital based, randomized, comparative type of observational study, 25 patients were included in each group. Each patient examined thoroughly and underwent radiological assessment. Follow-up done at 6 weeks, 3 months, 6 months, and 2 years and pain score, Harris Hip Score (HHS), subjective complaints, and joint stability were recorded. Results: Mean age of the patient in cemented group was 60.64 years and in uncemented group was 59.72 years. Pain score was compared at each follow-up which came out significant at 6 weeks (P ≤ 0.05) and 3 months (P = 0.002) explaining better early bone integration with cemented THR. However, at 6 months difference in pain score between two groups was nonsignificant (P = 0.176). Difference in function score between cemented and uncemented group was significant at 6 weeks (P = 0.003) and 3 months (P ≤ 0.05) which later become nonsignificant at 6 months (P = 0.38). The difference of HHS between cemented and uncemented group was significant at 6 weeks (P ≤ 0.05) and 3 months (P = 0.011). This difference became nonsignificant at 6 months. HHS is further divided into four grading – poor (<70), fair (70–79), good (80–89), and excellent (90–100). Overall in our study, 88% of patients in cemented group showed excellent and good results and 84% in uncemented group showed excellent and good results. There was one case of excessive blood loss during surgery in uncemented group and one case of foot drop in cemented group. Conclusion: Cemented implants are cheaper than the uncemented implants. Better short-term clinical outcomes mainly improved pain and early pain-free full weight bearing was obtained from cemented fixation.
|
2022-03-04T08:21:20.569Z
|
19,952,328 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1053/j.semtcvs.2011.07.008",
"MAG": "1972358950",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Left ventricular assist devices (LVADs) are the treatment of choice for advanced heart failure that is refractory to medical therapy for both Bridge to Transplantation and Destination Therapy in appropriately selected patients. The newer continuous flow LVADs are more reliable and durable and have resulted in significant size reduction compared to pulsatile flow LVADs. This "miniaturization" of the LVAD has potential advantages including less surgical trauma for implantation. The HeartWare HVAD is a new continuous flow LVAD, currently in trials, that is designed to be implanted and contained completely within the pericardial space.
|
2022-09-09T20:33:15.532Z
|
207,973,046 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/TLA.2019.8891941",
"MAG": "2987142484",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The exponential growth in the number of mobile subscribers, as well as the data traffic generated by them is showing a major challenge in wireless Internet. Existing mobile networks are starting to be insufficient in meeting this demand, in part due to their inflexible and expensive equipment as well as complex and non-agile control plane. In this context, in which the heterogeneity on the access is even more extended, the mobility support becomes more crucial. Thus, the mobility management mechanisms need to evolve to fit with the cutting-edge technologies that are going to rule next generation mobile networks. A key enabler to 5G will be SDN (Software-Defined Networking), which brings a natural solution to decouple the network control plane from the data plane, allowing higher flexibility and programmability to the network. Based on SDN and following the recommendations of the DMM (Distributed Mobility Management) approach, this article presents the SR-DMM solution (SDN Redirection DMM), a mobility management mechanism that takes full advantages of the softwarization capabilities of the network. This proposal avoids the use of IP-IP tunnels and it adds the dynamic flow management capability provided by SDN. In order to analyse the performance of SR-DMM, an analytical model is developed to compare it with NB-DMM (Network-based DMM), one of the main DMM solutions. Additionally, SR-DMM performance is also evaluated with an experimental testbed. The results allow to measure the handover latency in real scenarios and numerical investigations, also shows that SR-DMM achieves better efficiency in terms of signalling and routing cost than NB-DMM solution.
|
2022-09-13T10:38:07.673Z
|
250,312,363 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1039/d2ob00767c",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Spirocyclic frameworks have attracted synthetic practitioners due to their unique three-dimensional assembly, improved metabolic stability, solubility, and increased molecular complexity with regard to planar architectures. A recent surge in the number of spirocyclic oxindoles inhibiting enzymes, moderating unique protein-protein interactions, modulating receptors and transporters is testament to their prevalence. Against this background, the construction of spirocyclic frameworks containing an oxindole moiety as a torsional switch via stereoselective methods is in great demand. Herein we present a summary of the past three years in the progress of metal, organic molecule, nanostructured particle mediated, and even uncatalyzed versions of the highly diastereo- and enantioselective pathways leading to oxindole spirocycles.
|
2022-10-13T07:52:08.315Z
|
117,866,573 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1046/J.1365-8711.2000.03876.X",
"MAG": "2098408882",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
By using a non-local time-dependent theory of convection, the non-adiabatic oscillations of the radial p-modes of the Sun were calculated. The coupling between convection and oscillation and the influence of departure from radiative equilibrium on oscillations of p-modes were investigated in detail. The results of numerical calculations show that when the coupling between convection and oscillations is ignored, all the low-order radial p-modes with n less than or similar to 10 are pulsationally unstable and all the intermediate- and high-order (n greater than or similar to 11) radial p-modes are pulsationally stable. When the coupling between convection and oscillations is taken into consideration, only the intermediate-order p-modes with 11 n less than or similar to 23 are pulsationally unstable and all the low-order (n less than or similar to 10) and high-order (n greater than or similar to 24) p-modes are pulsationally stable. The behaviour of stability of the solar p-mode oscillations described above is the result of the joint action of radiation and convection on oscillations. In the interior of the convection zone, the thermodynamic coupling between convection and oscillations gives rise to damping of solar oscillations, but at the top of the convection zone, it causes excitation. The thermodynamic coupling between convection and oscillations plays a key role in the stabilization of low-frequency solar p-modes and also in the excitation of the intermediate-order solar p-mode oscillations with periods of about 5 min. The turbulent pressure generally causes excitation. The radiative damping in the outer atmosphere and the turbulent viscosity are the main damping mechanisms of the high-order (nu greater than or similar to 4000 mu Hz) solar p-modes. For the low-order p-mode oscillations with nu less than or similar to 1000 mu Hz, the departure from radiative equilibrium (DRE) does not have a significant effect. With the increase of frequency, the influence of the outer atmosphere and the DRE grows rapidly. The generalized Eddington approximations (GEA) developed by Unno & Spiegel and Mihalas are much better than the usual radiative diffusion approximation. Our conclusion is as follows: the coupling between convection and oscillations is an important excitation and damping mechanism for solar 5-min oscillations. However, it cannot be used to interpret all the observational characteristics of solar p-modes. There must be excitation and damping mechanisms other than the radiation and the 'regular' coupling between convection and oscillations.
|
2022-10-25T10:21:44.364Z
|
156,119,353 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2307/2612435",
"MAG": "2331505531",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
T nwo concepts, variously expressed and justified, limit the effectiveness of the technical assistance and financial aid-which are closely linked-provided by the Western countries for the peoples of the Third World. The first, often described as ' intellectual neo-colonialism', is that of excessive numbers of experts and technicians, unreservedly convinced both of the superiority of Western civilisation (and in particular of our way of life) over any other, and of the absolute value of the scientific and technical knowledge which they want to transfer to developing countries, often without any concern for the geographic and sociopolitical realities of these countries. The second concept, more generous in spirit, has, in theory, a considerable basis of truth, but it receives little practical application today. This is the concept of well-meaning people who prefer the formula of 'co-operation ' to that of ' technical assistance', and who would base this co-operation on the idea of reciprocity. It is certainly true that the West would have much to gain from a real understanding of the importance attached by India to the efforts of men to change and improve themselves from within, from a better knowledge of the Chinese philosophy of everyday behaviour, from an effort to learn, from the example of Africa, to revive in ourselves a sense of spontaneity and the role of instinct. ... But the technicians and the organisers, or even the teachers who are sent to Asia and Africa to fight against poverty, hunger, ignorance, and low productivity in general, are not those best placed to be aware of the usefulness of an exchange of ideas in the realms of civilisation and philosophy and we have nowadays practically no occasiotn to observe examples of much co-operation. What is important for these Western experts is to understand that their task of ' communicating knowledge and transferring experience ' cannot be usefully pursued unless this knowledge and experience is previously adapted to the concrete realities of the countries receiving the aid, and, therefore, unless they are aware of, or become aware of, those realities. From this necessity two consequences arise which, however paradoxical they may seem, must be taken into account in the field of technical assistance. ** *
|
2022-12-03T21:28:01.248Z
|
109,290,646 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1063/1.3292318",
"MAG": "1994305340",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
To optimize the signal efficiency in detectors utilizing Transition Edge Sensor (TES) technology we have fabricated and characterized test devices which approximate the electrical and thermal properties of the tungsten TES parallel arrays used for the Cryogenic Dark Matter Search (CDMS) phonon sensors. We measure the equilibrium power as a function of bias voltage by sweeping the bias current through the TES array and measuring the resulting current through the sensor. Our results are in agreement with previous estimates of the critical length for a TES to separate into superconducting and normal phases. However, we found that the presence of the tungsten sections, which connect the TES to the aluminum fins, significantly shortens the critical length for the onset of phase separation, and indicate that many CDMS phonon sensors have operated with phase separated TESs. We have also improved the determination of the electron‐phonon coupling in our tungsten films to be (0.32±0.02)×109W/m3K5. Finally, we also found that the thermal conductance between the tungsten electron and phonon systems does not scale linearly with added fin connector volume, instead ∼75% of added volume contributes.To optimize the signal efficiency in detectors utilizing Transition Edge Sensor (TES) technology we have fabricated and characterized test devices which approximate the electrical and thermal properties of the tungsten TES parallel arrays used for the Cryogenic Dark Matter Search (CDMS) phonon sensors. We measure the equilibrium power as a function of bias voltage by sweeping the bias current through the TES array and measuring the resulting current through the sensor. Our results are in agreement with previous estimates of the critical length for a TES to separate into superconducting and normal phases. However, we found that the presence of the tungsten sections, which connect the TES to the aluminum fins, significantly shortens the critical length for the onset of phase separation, and indicate that many CDMS phonon sensors have operated with phase separated TESs. We have also improved the determination of the electron‐phonon coupling in our tungsten films to be (0.32±0.02)×109W/m3K5. Finally, we also ...
|
2022-11-18T11:02:00.116Z
|
159,137,775 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/amp.2019.40",
"MAG": "2925192069",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
My comments today seek to highlight how social and economic rights advocates, particularly those concerned with the right to health, engage with ongoing debates about the role of criminal law in human rights. In particular, I emphasize how many “right to health” campaigns fight for the decriminalization of laws that result in the arrest of marginalized communities or health workers. This trend within right to health advocacy complicates what has been called the anti-impunity turn in human rights. In other words, although many scholars have correctly highlighted the rise of a carceral agenda in human rights, there is also ongoing, and perhaps growing, emphasis on decriminalization in the context of social and economic rights. This presentation gives a brief overview of the fight for decriminalization in the context of the right to health, highlights the challenges faced by advocates of in those campaigns, and reflects on some cautionary tales emerging from these fights for decriminalization.
|
2022-12-12T00:06:15.164Z
|
97,461,477 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1081/CSS-120000957",
"MAG": "2077610228",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The purpose of this study was to measure corn response to nitrogen (N), to evaluate the feasibility of using the pre-sidedress soil nitrate test (PSNT) for making fertilizer N recommendations for silage corn, and to evaluate the environmental and economic implications of adopting fertilizer N recommendations based on the PSNT in south coastal British Columbia, Canada, a region of high soil N fertility. Eighty-seven trials were conducted from 1994–1996 with corn or forage grass as a preceding crop on fields having a history of manure application. Non-manured trials received no spring manure application whereas manured trials received a spring application typical of that farm field. In 1994, treatments included sidedress N rates of 0, 30, 60, 90, 120, and 150 kg N ha−1 replicated twice. In 1995 and 1996, trials with less than 30 mg NO3-N kg−1 soil to 30 cm depth prior to sidedress received the same treatments as in 1994, whereas trials with concentrations above this value received two treatments, 0 and 150 kg N ha−1, replicated four times. Trials received less than 50 kg N ha−1 at planting. Yield response to sidedress N was limited, with 71, 87, and 55% of trials with 90% or higher relative yield (yield at 0 kg N ha−1 divided by yield at 150 kg N ha−1) in 1994, 1995 and 1996, respectively. The limited yield response was attributed to high soil N mineralization, which averaged 166 and 146 kg N ha−1 for non-manured trials in 1995 and 1996, respectively. The critical PSNT value (above which no yield response to sidedress N is expected) was predicted to be 19 and 23 mg NO3-N kg−1 soil using the Cate-Nelson procedure and a linear-plateau regression procedure, respectively. A critical PSNT test value of 32 mg NO3-N kg−1 soil was predicted using a linear-plateau regression of the estimated N rate which would maximize economic return (NMER) against PSNT test value. In addition, a model designed to minimize the risk of yield loss was developed with a critical PSNT test value of 30 mg NO3-N kg−1 soil. Average soil NO3 content at harvest was slightly higher for sidedress N rates based on the minimum risk model (70 kg N ha−1) than at NMER (64 kg N ha−1). Based on a survey of farm fields, the potential to reduce fertilizer N application in south coastal BC was estimated to be about 90 kg N ha−1 yr−1.
|
2022-12-12T20:56:43.301Z
|
232,188,438 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/mabi.202000396",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Protein-based hydrogels are important functional materials with many potential applications. However, the relatively small pore size and poor mechanical properties substantially limit their application. Here a superporous bovine serum albumin (BSA) hydrogel is prepared with high porosity and interconnectivity by using BSA and 1,2,7,8-diepoxyoctane (DEO). The equilibrium water contents of hydrogels can reach 76.5%. Moreover, the BSA hydrogels show excellent mechanical properties and excellent deformation recoverability, with a maximum compression modulus of 50 MPa at 75% strain and no residual strain generated after 500 cyclic compression tests. The resulting BSA hydrogel has excellent biocompatibility for cell adherence and is nonbiodegradable for 40 weeks. More importantly, the BSA hydrogel exhibits excellent hemostatic ability, with hemostatic times in a rabbit ear artery and rabbit liver of 33 and 28 s, respectively. Therefore, BSA hydrogels have potential applications as painless nonadherent wound dressings and implant materials for plastic surgery.
|
2022-12-20T00:50:22.154Z
|
5,503,865 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1467-8535.2012.01360.X",
"MAG": "1856829404",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Key to introducing information and communication technologies in museums is to support meaning-making activity in encounters with artefacts. The study presented in this paper is exploratory in nature and investigates the use of social and mobile technologies in school field trips as a means of enhancing the visitor experience. It is anchored in sociocultural perspectives of learning as meaning making, with a focus on mediating artefacts in the development of understanding. The Museum of London was selected as the site of the study and the participants were a Year 9 History class (13-14 years old) in a secondary school in Milton Keynes. The paper considers evidence of meaning making from students' online posts on Twitter (http://twitter.com) and activity on-site. Observational data, the visit's Twitter stream and post-visit interview data with the participants are presented and analysed. A mixed-method approach is employed to interpret the museum visit and examine young people's experience in the museum. Such an approach allows useful insights and shapes the understanding of how social and mobile technologies have an impact on the social dynamics of a school trip to a museum. Specifically, it explains the role of such tools in fostering the social interactions around museum artefacts and ultimately the process of shared construction of meaning making. Practitioner Notes What is already known about this topic School field trips are an important means of introducing young people to museum collections and have long-term learning impact and influence perceptions., Learning in museums is conceptualised as the construction of meaning. Making meaning is a social practice-people engage with their environment and each other through 'socially made and culturally specific resources, in ways that arise out of their interests' (Kress, )., Facilitating the visitors' meaning-making process is key to introducing new technologies in museums (Kaptelinin, )., Use of mobile tools in museum facilitates inquiry activities such as exploration, information search, communication and experience documenting (Hsi, )., Many information technologies implemented in museum and field trips fail to meet the real needs of their users (Gammon & Burch, ) and may appear to isolate visitors and inhibit social interaction (vom Lehn & Heath, )., What this paper adds Explores the use of social and mobile technologies at the interface of formal and informal contexts in K-12 education., Provides an example of 'enforced' mobile usage (Rushby, ) with empirical evidence on how social and mobile technologies could be integrated in school field trips to museums., Focuses on a learning design that allows learners to switch between different contexts (offline/online; individual/social; formal/informal) and extend the social spaces in which learners interact with each other., Employs a mixed-method approach in analysing content generated online in a school visit to a museum., Contributes to a research agenda for mobile learning and particularly in designing and studying 'seamless learning spaces'., Implications for practice and/or policy The findings will contribute to museum education initiatives for effective use of social and mobile tools within school programmes., Indicates the potential of the 'interconnected opinion space' and 'archival space' in designing museum programmes for meaning making across contexts., Highlights the need to develop more effective pedagogic strategies that will anticipate and encourage the ways that young people use social and mobile technologies and at the same time minimise the tension between the contexts, the content and the mediation tools. [ABSTRACT FROM AUTHOR]
|
2023-01-01T18:20:02.554Z
|
128,752,016 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1144/1467-787302-045",
"MAG": "2044610696",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Geochemical sampling of groundwater may be an effective tool in exploring for Au deposits in areas of transported overburden. However, to use hydrogeochemistry effectively, we need to understand which elements are useful pathfinders and how their distribution patterns are affected by groundwater flow and geochemistry, especially in areas that have hypersaline groundwater. A hydrogeochemical survey was completed over the strongly Au-endowed St. Ives area of the Eastern Goldfields of Western Australia. Extensive geochemical and hydrogeological data were measured from 80 holes drilled on a kilometre-spaced grid. A numerical model was developed to quantify the groundwater flow regime in the study area. Also, hydrogeological data in combination with the geochemistry of the waters were used to identify a complex flow regime adjacent to Lake Lefroy, a playa lake in the area. Regional brine flows towards the salt lake, evaporation occurs and hypersaline (playa) brines are formed that sink and flow away from Lake Lefroy and beneath the regional brines. Density-driven, convective mixing of these two brines is responsible for forming a zone of brines with transitional compositions located near the edge of Lake Lefroy. Knowledge of the groundwater flow regime was used to interpret the distribution of elements around bedrock Au mineralization. An Au-only groundwater anomaly (>10 ppt, maximum 52 ppt) is located downstream of the Junction Au ore body. No anomaly was identified in deep brines associated with the nearby Argo/Apollo Au ore body; however, shallow regional brines sampled in a previous survey showed elevated Au values overlying and downstream of the mineralization. The lack of elevated Au concentrations in deeper groundwater associated with Argo/Apollo is because the samples collected were hypersaline playa brines sourced from Lake Lefroy that had not flowed over the mineralization. Possible pathfinder elements, such as Sb, Bi and Te, were either present in concentrations too low to detect or showed no spatial pattern related to known mineralization; however, a strong correlation was noted between some of their concentrations and salinity. Evaluation of the groundwater anomalies observed in this study suggests that hydrogeochemical exploration is most effective at a resolution of 0.5–4 km spacing, and does not require fully cased and packed wells, at least in cases where no confined aquifers are intersected in drilling. The results of this study illustrate the importance of understanding groundwater flow regimes in planning and interpreting hydrogeochemical surveys.
|
2022-09-12T12:36:51.966Z
|
44,764,900 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1136/ard.40.5.531",
"MAG": "2062796987",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://ard.bmj.com/content/annrheumdis/40/5/531.full.pdf"
}
|
SIR, We were interested to read the report of Scott et al.1 but consider that they have confused 2 clinical entities and that their conclusions are misleading. We agree that gold causes an acute pulmonary syndrome as they have described. Our own review article2 has summarised the usual features-the onset of dyspnoea and cough, sometimes with fever, the finding of fine basal rales clinically, a restrictive ventilatory defect, and the radiological evidence of pulmonary infiltrates, which all occur after a total gold dose of between 175 and 840 mg in the reported cases. We have termed this syndrome 'gold lung.' However, of the 7 patients treated with D-penicillamine reviewed by Scott et al. only 3 had an undoubted acute syndrome akin to gold lung, which might be called 'penicillamine lung.' The other 4 patients developed a form of Goodpasture's syndrome. Radiological 'infiltrates' seen in this condition are due to haemorrhage, and any fibrosis that may be seen is secondary to haemosiderin deposition. We cannot accept that Goodpasture's syndrome is a form of pulmonary interstitial fibrosis or of 'diffuse interstitial lung disease,' a rather loose term used by Scott et al. following the criteria of Walker and Wright. 3 We would further point out that in the quoted paper by Sternleib4 all 3 patients had Wilson's disease and were given much larger doses of D-penicillamine than are used in rheumatoid arthritis, and that the lung histology reported (and this only in one patient) does not support a diagnosis of 'diffuse interstitial lung disease.' Our own review article shows that in cases of 'gold lung' recovery is the rule.2 Goodpasture's syndrome was untreatable, and nearly always fatal, at the time of Sternleib's paper, but the prognosis is now much better following the introduction of plasmapheresis. Thus it is most important from the point of view of management to make a clear distinction between the syndrome of 'penicillamine lung' and penicillamine-induced Goodpasture's syndrome. The contention that 'diffuse interstitial lung disease is a serious adverse reaction to gold and penicillamine' is unsupportable. Of the 4 deaths described in Scott et al.'s report 3 were of patients with Goodpasture's syndrome, which is unsurprising. The fourth death was ofa patient in Gould's series5 with gold lung, but this was not the cause)of death-the patient died of a myocardial infarction 24 hours after admission. The figures now look rather different. Twenty-three cases of gold or penicillamine lung
|
2022-11-18T01:01:21.583Z
|
15,519,448 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1051/ro:2007009",
"MAG": "2155104777",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "http://www.numdam.org/item/10.1051/ro:2007009.pdf"
}
|
We describe the solution of a bound constrained convex quadratic problem with limited memory resources. The problem arises from physical simulations occurring within video games. The motivating problem is outlined, along with a simple interior point approach for its solution. Various linear algebra issues arising in the implementation are explored, including preconditioning, ordering and a number of ways of solving an equivalent augmented system. Alternative approaches are briefly surveyed, and some recommendations for solving these types of problems are given.
|
2022-12-09T16:08:17.230Z
|
154,839,134 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/00036840122752",
"MAG": "2051848828",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper calculates cigarette demand for race groups in South Africa. Elasticities are the most important information a tax policy analyst can have. Elasticities determine how the tax base will change with a change in the tax rate and thus how government revenues will respond to the tax. Elasticities also determine the excess burden that consumers will bear as a result of the tax. As such, own price, crossprice, and expenditure elasticities are calculated along with government revenue maximizing tax rates, and total and excess burdens. Parametric and semiparametric estimation techniques are used and compared. Results show that a tax on cigarettes will discourage nonsmokers from starting to smoke and mainly raise revenue from current smokers. Furthermore, it is found that consumption behaviours between groups are different implying different government revenue maximizing tax rates for each group affecting the distribution of income.
|
2022-12-11T23:21:29.088Z
|
168,367,009 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2139/SSRN.2800623",
"MAG": "2493645308",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Private property income can only be reported by letter and not on a Canada Revenue Agency (“CRA”) T1 form. Only income deemed by law to be Canada’s “public money” is filed on a T1. CRA uses the SIN two ways: as a Social Insurance Number and also as a “social insurance number” to identify individual taxpayers as two legal persons with two separate legal capacities.
|
2022-12-17T23:54:49.540Z
|
118,478 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/MPRV.2003.1203757",
"MAG": "2126681705",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The availability of massive amounts of high-quality data as well as advances in computing and communications suggest the possibility of powerful new applications in science, commerce, environment, and government-but many research challenges remain. Research in geospatial information systems is inherently multidisciplinary, and research efforts are likely to be most successful if conducted by teams that combine expertise in applications as well as information technology. Advances in location-aware computing, in particular, could have important implications not just for how geospatial data are acquired but also for how and with what quality they can be delivered and how mobile and geographically distributed systems are designed.
|
2022-12-20T03:33:30.183Z
|
248,209,555 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.18231/j.ijpns.2022.001",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBYNCSA",
"status": "HYBRID",
"url": "https://doi.org/10.18231/j.ijpns.2022.001"
}
|
Palliative care improves the life quality of client and also for their families who are suffering with challenges associated with life-threatening illness, whether physical, psychological, social or spiritual. The quality of caregiver’s life also improves. According to WHO each year, an estimated 40 million people are in need of palliative care; 78% of them people live in low- and middle-income countries. Worldwide, only about 14% of people who need palliative care currently receive it. Unnecessarily restrictive regulations for morphine and other essential controlled palliative medicines deny access to adequate palliative care.
|
2022-04-22T04:48:37.853Z
|
241,973,956 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/med/9780198809821.003.0011",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In low-resource settings regional anaesthesia forms an essential part of anaesthetic practice, especially in the context of poor access to postoperative analgesia and recovery facilities, or where general anaesthesia is not available or may be high risk. Safe practice for performance of regional anaesthesia is outlined as well as the emergency management of local anaesthetic toxicity. The chapter covers a range of upper limb, lower limb, and trunk blocks. It describes, where possible, ultrasound, nerve stimulator, and landmark techniques for each block since available equipment may vary. Neuraxial techniques for neonates, infants, and children are described along with local anaesthetic dosages.
|
2022-07-01T03:33:00.051Z
|
151,591,103 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1515/PPB-2016-0047",
"MAG": "2559841257",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
: A study was carried out involving persons representing high-anxious, low-anxious and repressor types according to the classification of Weinberger, Davidson & Schwartz (1979), selected using the Marlowe–Crowne Social Desirability Scale and the trait anxiety scale of the Spielberger State–Trait Anxiety Inventory. In seeking indicators of anxiety in repressors and high-anxious groups, the authors decided to analyse the level of dogmatism observed in utterance texts. The research was intended to determine whether styles of coping with threatening stimuli condition the level of dogmatism, which was regarded as a cognitive defence mechanism against anxiety. The method of formal analysis of texts (speeches given by the participants in a situation of social exposure) was used to identify their level of dogmatism, measured using the Dogmatism Quotient developed by Ertel. The highest value of the Dogmatism Quotient was recorded for repressors, and the lowest for the low-anxious subjects; a similar pattern was also observed for certain particular dimensions of dogmatism. Statistically significant differences in the level of dogmatism were found between the repressor and low-anxious groups and between the high-anxious and low-anxious groups. The study confirmed the previously discovered pattern whereby repressors exhibit more similarities to high-anxious than to low-anxious persons.
|
2022-07-06T06:47:11.470Z
|
95,701,711 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/ZAAC.19522680104",
"MAG": "2040872185",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Das Natriumsalz der Hexafluorophosphorsaure kristallisiert als Monohydrat; dieses last sich leicht entwassern. Das wasserfreie Salz kristallisiert kubisch, die Gitterkonstante betragt 7,61 A, die Elementarzelle enthalt 4 Molekeln. Fur die Struktur dieses wasserfreien Salzes wird in Anlehnung an die Struktur des KPF6 ein Vorschlag gemacht.
|
2022-09-12T08:47:49.310Z
|
166,407,058 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2139/ssrn.606822",
"MAG": "1573087598",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We examine the effect of the Private Securities Litigation Reform Act of 1995 and the Securities Litigation Uniform Standards Act of 1998 on analyst recommendations. We refer to these acts as the Reform, which addresses the safe harbor provision for forward-looking information. After controlling for other variables, we find higher short-term market reaction following recommendation revisions after the Reform, suggesting that analysts play an increasingly important role. We also find that following upgrades (downgrades), the long-term drifts increase (decrease) in magnitude, and price reversions are less (more) likely.
|
2022-09-12T04:12:52.557Z
|
30,532,507 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/026988119901300108",
"MAG": "2082482584",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Many mentally ill women want to breast-feed their babies but, if theyare taking psychotropic drugs, there is very little systematic data upon which to base decisions about whether or not it is safe to do so.We therefore attempt to provide a comprehensive and critical summary of existing case reports and of studies of breast-feeding in relation to commonly used psychotropic drugs. The literature review focuses on the following drugs: antidepressants: tricyclics and serotonin selective reuptake inhibitors (SSRIs); antipsychotic drugs: chlorpromazine, perphenazine, haloperidol and clozapine; mood stabilizers: lithium and carbamazepine; and benzodiazepines. The research literature consists mainly of single case reports and there have been very few attempts at controlled, longitudinal investigations. Findings are often difficult to compare because of differences in methods or because of lack of key information. Most data are available about the tricyclic antidepressants but even here we have found that the reports cover only a grand total of 66 mother-infant pairs. Dilemmas about whether or not to contraindicate breast-feeding arise most commonly in relation to postnatal depression. The findings to date suggest that provided that infants are healthy at the outset it is likely that the benefits of breast-feeding will outweigh potential hazards if their mothers are taking established tricyclic drugs at recommended dose levels. Much less is known about risks associated with SSRI antidepressants or about antipsychotic drugs such as phenothiazines and butyrophenones or mood stabilizers such as carbamazepine, all of which enter breast-milk. Safeguards are suggested for future single case studies, which, as they accumulate, will provide a platform for mounting controlled prospective studies properly to test for any acute toxic effects and for possible long-term adverse effects of such drugs on infants' development. Appendix 1 is a review of assay methods. Appendix 2 examines pharmacokinetic factors in newborn preterm and sick infants with special reference to contraindications to breast-feeding. Appendix 3 is a review of methods for assessing infant health and development.
|
2022-09-14T11:19:59.482Z
|
225,774,465 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/su12135283",
"MAG": "3038832896",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2071-1050/12/13/5283/pdf?version=1593516183"
}
|
The paper proposes a new hybrid method based on cuckoo search (CSA) and sunflower optimization (SFO) approach (called HCSA-SFO) for improving the performance of solutions in the optimization power system operation problem. In the power system, the optimal power flow (OPF) problem is one of the important factors which usually minimizes total cost and total active power losses while satisfying all constraints of the output power of generators, the voltage at buses, power flow on branches, the capacity of capacitor banks and steps of transformer taps. HCSA-SFO utilizes the mutation and selection mechanism in the SFO algorithm to replace the Lévy flights function in CSA. Hence, this makes HCSA-SFO avoid the fixed step size in the CSA from that can reduce run time and improve the quality of solution for the HCSA-SFO algorithm in the OPF problem. The proposed hybrid technique is simulated on the 30-buses and 118-buses systems. The obtained simulation results from the suggested technique are compared to many other approaches. The result comparisons in different cases showed that the suggested HCSA-SFO can achieve a better result than many other optimization approaches. Therefore, the suggested HCSA-SFO is also an effective approach for dealing with the OPF problem.
|
2022-12-02T10:17:55.821Z
|
136,072,790 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2320/JINSTMET1952.65.7_607",
"MAG": "2607037484",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Control of noise and vibration remains to be solved for the lowering of environmental load in all the industrial fields. It is necessary to take account of the noise and vibration problem when designing machines or structures. Therefore the development of damping materials suitable for structural parts that are easy to process and recycle, is urgently required. MnCu damping alloys show the most satisfactory mechanical properties and damping capacity among the developed damping alloys. The M2052 damping alloy, which has a nominal composition of Mn20Cu5Ni2Fe (at), shows both a high damping capacity and a high strength. The damping capacity of M2052 alloy increases to a high level below a certain temperature, and the damping level also varies sensitively to the changes in vibration frequency and strain amplitude. By the peakshift method the thermal activation energy for the {101} twin boundaries responsible for the lowtemperature damping peak is calculated to be 4.88×104 J/mol. The tensile strength of the alloy is 500 MPa, accompanied with a superior workability for practical applications. It is confirmed experimentally that M2052 damping alloy is quite effective in damping the intolerable vibrations when used as structural parts.
|
2022-07-23T09:31:17.936Z
|
55,143,352 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1748-9326/6/1/014002",
"MAG": "2075373322",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://doi.org/10.1088/1748-9326/6/1/014002"
}
|
Different options have been suggested by Parties to the UNFCCC (United Framework Convention on Climate Change) for inclusion in national approaches to REDD and REDD + (reduced deforestation, reduced degradation, enhancement of forest carbon stocks, sustainable management of forest, and conservation of forest carbon stocks). This paper proposes that from the practical and technical points of view of designing action for REDD and REDD + at local and sub-national level, as well as from the point of view of the necessary MRV (monitoring, reporting and verification), these should be grouped into three categories: conservation, which is rewarded on the basis of no changes in forest stock, reduced deforestation, in which lowered rates of forest area loss are rewarded, and positive impacts on carbon stock changes in forests remaining forest, which includes reduced degradation, sustainable management of forest of various kinds, and forest enhancement. Thus we have moved degradation, which conventionally is grouped with deforestation, into the forest management group reported as areas remaining forest land, with which it has, in reality, and particularly as regards MRV, much more in common. Secondly, in the context of the fact that REDD/REDD + is to take the form of a national or near-national approach, we argue that while systematic national monitoring is important, it may not be necessary for REDD/REDD + activities, or for national MRV, to be started at equal levels of intensity all over the country. Rather, areas where interventions seem easiest to start may be targeted, and here data measurements may be more rigorous (Tier 3), for example based on stakeholder self-monitoring with independent verification, while in other, untreated areas, a lower level of monitoring may be pursued, at least in the first instance. Treated areas may be targeted for any of the three groups of activities (conservation, reduced deforestation, and positive impact on carbon stock increases in forest remaining forest).
|
2022-12-25T07:06:54.137Z
|
144,724,106 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/TL.7807",
"MAG": "2034041831",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A supportive teaching culture provides various forms of informative feedback about individual teaching effectiveness without threatening individual teachers. This supportive approach stimulates motivation to achieve excellence in teaching.
|
2022-12-25T18:15:30.505Z
|
101,060,403 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/JZ402090D",
"MAG": "2335674073",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
First-principles investigations of the electrocatalytic activity toward the four-electron oxygen reduction-reaction in N-doped graphene quantum dots reveal that pyridinic and graphitic nitrogen are the most active sites with overpotentials of 0.55 and 0.79–0.90 V, respectively. This agrees with experimental findings. Our calculations account for van der Waals interactions, solvent effects, and describe the electrochemistry using standard hydrogen electrode model. The results show correlations between OH*, OOH*, and O* binding energies that impose a lower limit on the oxygen reduction overpotential.
|
2022-12-31T19:03:24.962Z
|
138,257,120 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5794/JJOMS.42.72",
"MAG": "2315041099",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Imaging technique advancements have contributed to improved understanding of the pathogenesis of internal derangement of the temporomandibular joint. Although repositioning of the dislocated disc is the most commonly employed to treat this condition, discectomy is indicated for degenerated discs. Arthritic changes have been observed in joints after disc removal, suggesting the need for interpositional material. Since silicone implants placed after discectomy have caused osseous destruction, there is controversy about the use of interpositional materials after discectomy. Recent studies recommend the use of autogenous materials for replacement. Among them, auricular cartilage seems one of the best suited materials for disc replacement. The purpose of this study was to investigate morphological and functional changes after auricular grafts were placed in temporomandibular joints after disc removal. Rabbits for this experimental study were divided into two groups: rabbits in one group underwent discectomy alone, and the other group underwent auricular grafting after discectomy. H & E stain and toluidine blue stain revealed complete resorption of the articular cartilage with surface flattening in the discectomy alone group. Finally, regeneration of the fibro-cartilage cells resulted in retention of the articular cartilage layer on the condyle with a flattened articular surface. In contrast, a virtually normal shape was maintained in the auricular graft group, but the implant underwent resorption and fragmentation after 6 weeks. Finally, a depression was formed only on the surface of eminence. The results indicated that grafted auricular cartilage protected the rabbit condyle from early degenerative changes and suppressed morphological changes after discectomy.
|
2022-02-09T10:11:41.604Z
|
125,713,499 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1121/1.4987353",
"MAG": "2622403353",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Cochlear implant (CI) users have access to fewer acoustic cues than normal hearing listeners, resulting in less than perfect identification of phonemes (vowels and consonants), even in quiet. This makes it possible to develop models of phoneme identification based on CI users’ ability to discriminate along a small set of linguistically-relevant continua. Vowel and consonant confusions made by CI users provide a very rich platform to test such models. The preliminary implementation of these models used a single perceptual dimension and was closely related to the model of intensity resolution developed jointly by Nat Durlach and Lou Braida. Extensions of this model to multiple dimensions, incorporating aspects of Lou’s novel work on “crossmodal integration,” have successfully explained patterns of vowel and consonant confusions; perception of “conflicting-cue” vowels; changes in vowel identification as a function of different intensity mapping curves and frequency-to-electrode maps; adaptation (or lack ther...
|
2022-02-09T16:37:19.921Z
|
59,353,375 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.15330/jpnu.4.1.126-132",
"MAG": "2626394275",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://doi.org/10.15330/jpnu.4.1.126-132"
}
|
The article presents reasonably organizational and pedagogical conditions of professional self-development of primary school teachers, namely: support of positive motivation of achievement as meeting internal needs of the individual in professional self-development; the use of cognitive and informative opportunities of the content psychological and pedagogical and methodical disciplines for the formation of didactic complex and technological knowledge and skills, abilities to integrate spatial and substantive, informative and motivational, psychological, social and communication components of the educational environment of teachers’ training college; creating rich social and communicative space in the course of interactive cooperation of learning subjects to create students’ “success situations” and demonstrating positive experience of the professional success. The result of these organizational and pedagogical conditions of the professional self-development of primary school teachers have reflexive-value treatment to the personality as a future teacher and professional considering his or her strengths and weaknesses, formed a high level of readiness for professional self-development in his or her chosen profession.
|
2022-05-27T01:04:02.960Z
|
158,238,657 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2139/ssrn.3167543",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper maps and evaluates the development of digitalisation in the Netherlands, with a focus on civil justice. It describes and analyses legislative novelties and the actual progress that has been made in implementing technology in the judiciary, and examines key private, out-of-court initiatives in this area. While a full analysis in the context of this paper is not possible, it will attempt to draw some conclusions on the potential and challenges of these developments in enhancing access to justice.
|
2022-02-08T23:50:57.021Z
|
68,187,210 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2335/SCS.40.164",
"MAG": "40133314",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
To evaluate the efficacy and safety of CT angiography (CTA) performed at immediate early postoperative periods in patients with ruptured intracranial aneurysm, we retrospectively analyzed the modality and timing of postoperative evaluation following clip placement for ruptured intracranial aneurysms in our institution during the last decade. Between 2001 and 2007 (Phase A: 281 cases), postoperative evaluation with digital subtraction angiography was performed on or after 14 postoperative days (POD) in the majority of the subjects, except for some postoperative imaging that was done earlier. Re-ruptures were observed in five cases (1.8% of total cases in Phase A), of which three aneurysms bled within two weeks after surgery. Since 2008, we have used the CTA for evaluation in the early postoperative period (Phase B: 102 cases). In particular, after 2009, all patients underwent immediate (POD 1) CTA to exclude aneurysm remnants as early as possible. No adverse incidence was observed during this protocol. In the Phase B period, two small remnants of anterior communicating artery aneurysms (AcomAN, 2.0% of all cases in Phase B) were detected in the CTA on POD 1. The patients in whom aneurysm remnants were found immediately underwent a second surgery to prevent re-rupture. Our findings suggest that immediate postoperative examination (POD 1) by CTA is beneficial to detect an incomplete closure of aneurysms before the postoperative vasospasmic phase. CTA was
|
2022-08-28T13:36:14.899Z
|
1,493,353 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1749-6632.1991.tb17015.x",
"MAG": "2006349342",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Human neutrophil elastase (HNE) degrades a variety of macromolecular substrates other than elastin. One of these substrates, fibrinogen, is cleaved by HNE into progressively smaller unclottable We hypothesized that if we could identify a specific site of HNE proteolysis on the fibrinogen molecule, isolate and characterize the released fragment, and develop an assay for this peptide, we would have a useful marker of unopposed HNE action on fibrinogen. We reasoned that this test would provide important information given that neutrophils and fibrinogen are integral components of the inflammatory response. Accordingly, we set out to explore the interaction between HNE and fibrinogen.
|
2022-09-09T23:19:56.439Z
|
28,302,728 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/00220345860650080101",
"MAG": "2056941988",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Streptococcus mutans, the principal microbial etiologic agent of dental caries (Newbrun, 1978), is a fascinating pathogen. It is by far the most ubiquitous human pathogen, infecting many during the first year of life soon after tooth eruption and ultimately associating with some 95% of the population (Stiles et al., 1976). The microbe known as S. mutans is in reality a group of four separate species differing in serotype and in
|
2022-09-10T12:27:47.520Z
|
27,992,021 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1137/S003614109834394X",
"MAG": "1977830922",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We analyze the question of the limit process when the shear viscosity goes to zero for global solutions to the Navier--Stokes equations for compressible heat conductive fluids for the flows which are invariant over cylindrical sheets.
|
2022-12-18T10:39:01.354Z
|
167,369,705 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S0263967X00001464",
"MAG": "2328401474",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The arguments presented in this paper strongly support the stated intention of the European Commission that farm product prices must be set more competitively with the world market. Indeed, they go further. The only long-term sustainable agricultural policy for the European Community is to let farm products compete unsupported on a free-trade world market (the ultimate objective of the GATT negotiations). This does not deny either justification or need for some form of compensation to the present industry for the loss of support. However, the argument does clearly require that such compensation should be ‘neutral’ — that it should not distort or alter production and allocation decisions from those which would be taken in the absence of such compensation. The only genuinely neutral compensation would be single lump sum capital transfer through a government bond issue. However, failing this, definitely limited annual support payments independent of current production decisions and relating to past production quantities less than those which would be produced under uncompensated free-trade would be ‘quasi neutral’, and might as a result be acceptable as non-distorting under GATT. In this sense, the price reduction proposals currently being discussed are a definite step in the right direction, especially for cereals. Nevertheless, agriculture faces a continued period of difficult adjustment, especially difficult in the hill and upland areas. As far as conventional agriculture is concerned, there is little prospect of these areas being able to compete directly in the final consumer markets at world price competitive levels. Their comparative advantage will lie with the production of breeding and store animals, to be finished on grass or grain in more productive locations. Fewer people will be able to earn a full-time living from agriculture in these areas and other things being equal, hill and upland farms seem likely to become even more extensive ranching operations than is the case at present. However, other things are not equal. It seems likely that society will continue to value the non-productive elements of hill and upland agriculture, which in many cases are seen as adding to the amenity and landscape qualities of these regions. Since the demand for these features will grow, ways will be found to supplement farming incomes in these areas (especially) in order to conserve the landscape, wildlife and amenity characteristics.
|
2022-02-08T19:01:37.838Z
|
108,963,889 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4028/www.scientific.net/AMM.744-746.2267",
"MAG": "2025691248",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The low carbon sustainable residential evaluation system devotes to saving energy, reducing emission, and optimizing the living environment, which plays a key role in coping with global warming and the sustainable development of human. It was introduced and analyzed comprehensively the most representative international residential appraisal systems—British Code for Sustainable House, American LEED, Japanese CASBEE, Chinese Evaluation Standard for Green Building and Chinese Ecological Residential Assessment Manual from the aspects of development process, evaluation content, evaluation software, evaluation system marketization, public education and so forth. It was also analyze the advantages and limitations of those residential evaluation systems, and put forward the problems of the present Chinese low carbon sustainable residential assessment system and the measures to improve the future low carbon sustainable residential evaluation systems.
|
2022-02-10T06:44:11.340Z
|
5,777,538 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/UCC.2014.70",
"MAG": "1995153988",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The focus of this paper will present Charge Flow which is a workflow based approach to manage the issue of chargeback within a Cloud environment. This work has been driven by the need for both private and public cloud operators to manage their virtualized infrastructures to ensure proper accountability so that resource usage is metered, charged and billed to the respective user of the virtualized resource. Charge Flow essentially automates and orchestrates the process of chargeback and charge view reducing the administrative overhead and increasing utilization of underlying resources.
|
2022-02-13T10:36:25.939Z
|
119,741,174 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CLEO.2000.907126",
"MAG": "2006370391",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Summary form only given.We report ultrafast time-resolved photoluminescence (PL) upconversion measurements of the carrier energy relaxation and carrier recombination in 1.3 /spl mu/m-wavelength, selfassembled, InGaAs-GaAs QDs. Results are described for temperatures ranging from 10-300 K and for excitation photon energies both above and within the wetting layer.
|
2022-01-27T02:16:37.430Z
|
253,437,895 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.6007/ijarbss/v12-i11/15224",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://hrmars.com/papers_submitted/15224/the-role-of-awareness-and-knowledge-toward-motor-takaful-purchase-intention-among-young-generation.pdf"
}
|
In Malaysia, the requirement to purchase a motor insurance is stated in the Road Transport Act 1987. It is a compulsory insurance policy for the owner of the motor vehicle in order to use the public road. There is no specific restriction to purchase as the decision to buy either conventional motor insurance or takaful products will depends on the insured’s c hoice. Recently, the demand for motor takaful is increasing tremendously due to several factors. Nevertheless, the market penetration of takaful products still lower than the conventional insurance. Lack of awareness and knowledge about the concept of takaful were some of the contributary factors based on previous studies. This research aims to discover the role of awareness and knowledge towards motor takaful among young generation. Primary data collection was used through online survey involving young generation. Data analysis was performed by using SPSS version 27.0 and descriptive statistics were used to define the respondents. The findings showed lack of awareness and knowledge among the young generation pertaining to the elements of motor takaful. This finding would be useful for the takaful operators to look into their marketing strategies to stay competitive in the insurance and takaful industry.
|
2022-11-11T08:07:48.552Z
|
207,082,459 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1137/S1064827502405112",
"MAG": "1980308665",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper is concerned with the solution of a linear system with multiple right-hand sides. Such problems arise from nonlinear, time-dependent, inverse, or optimization problems. In order to solve these problems efficiently we use block variants of the conjugate gradient method and combine them with cache aware algorithms. Further, we describe the acceleration of algebraic multigrid (AMG) methods by using such cache aware algorithms. Finally, numerical studies are presented that show the high efficiency of the proposed methods.
|
2022-12-19T08:09:02.755Z
|
15,505,543 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/ijms151017270",
"MAG": "2073734203",
"PubMedCentral": "4227161"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/1422-0067/15/10/17270/pdf?version=1411730631"
}
|
The debilitating effects of lower back pain are a major health issue worldwide. A variety of factors contribute to this, and oftentimes intervertebral disk degeneration (IDD) is an underlying cause of this disorder. Inflammation contributes to IDD, and inflammatory cytokines such as tumor necrosis factor (TNF)-α and interleukin (IL)-1β, play key roles in the pathology of IDD. Therefore, the development of treatments that inhibit the expression and/or effects of TNF-α and IL-1β in IDD patients should be a promising therapeutic approach to consider. This study characterized the potential to suppress inflammatory cytokine production in degenerative intervertebral disc (NP) cells by treatment with IL-10 and TGF-β in a canine model of IDD. IDD was induced surgically in six male beagles, and degenerative NP cells were isolated and cultured for in vitro studies on cytokine production. Cultured degenerative NP cells were divided into four experimental treatment groups: untreated control, IL-10-treated, TGF-β-treated, and IL-10- plus TGF-β-treated cells. Cultured normal NP cells served as a control group. TNF-α expression was evaluated by fluorescence activated cell sorting (FACS) analysis and enzyme-linked immunosorbent assay (ELISA); moreover, ELISA and real-time PCR were also performed to evaluate the effect of IL-10 and TGF-β on NP cell cytokine expression in vitro. Our results demonstrated that IL-10 and TGF-β treatment suppressed the expression of IL-1β and TNF-α and inhibited the development of inflammatory responses. These data suggest that IL-10 and TGF-β should be evaluated as therapeutic approaches for the treatment of lower back pain mediated by IDD.
|
2022-12-30T06:38:58.237Z
|
124,250,803 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1117/12.2202561",
"MAG": "2203475303",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
It is well known that effective medium description of metamaterials requires much caution, even for strongly subwavelength systems. Boundary effects play a dramatic role in finite samples with discrete structure, making their observable properties quite different from the predictions of effective medium theory. We report some new findings regarding the distinction between a homogenised response and actual properties of discrete structures, looking into canonical shape of metamaterial objects. Even for large size (up to 20000 “meta-atoms”), we observe a difference between large discretised spheres and a continuous one, which is important for practical design and future development of metamaterials. Finally, we also provide the results for non-resonant discrete finite systems
|
2022-01-27T02:11:35.080Z
|
142,933,358 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1741-3729.2008.00510.X",
"MAG": "1523013211",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We are pleased to introduce the Special Collection on Transnational Families. Editor Joyce Arditti first suggested this collection at the 2006 Groves Conference on Marriage and Family on "Families: Borders and Boundaries" in Tucson, Arizona, where we were energized by our many experiences talking with families living in Nogales on both sides of the U.S. border with Mexico. At that time, immigration policies were being vigorously debated in the press, in the halls of government, and in the streets of America. Yet, most political arguments did not seem reflective of the serious economic, emotional, and ethical issues facing immigrant families themselves. In addition, the traditional distinction between "immigrants" and "those left behind" is no longer clear in today's postmodern world when economic globalization, air travel, and Internet communication are increasingly common (Stone, Gomez, Hotzoglou, & Lipnitsky, 2005). In the United States, approximately 37.5 million people or about 12.5% of the U.S. population are foreign born, with more than one out of five children (23% of all children in the United States) currently living in an immigrant family (Migration Policy Institute, 2008). Living in one or more cultures and maintaining connections to both have been defined by immigration scholars as "transnationalism" (Waldinger & Fitzgerald, 2003). Transnational families are defined as families where some members of a family are anchored in one place but where family relationships transcend national boundaries. The myriad ways that transnational families sustain complex social relations between their societies of origin and settlement (Basch, Schiller, & Blanc, 1994; Bryceson & Vuorela, 2002) are of special interest to family scientists and practitioners. Thus, our broad aim in organizing this special collection is to highlight how applied child and family scholars contribute to intervention, program improvement, and policy development for transnational families. This collection of five articles includes original research focusing on immigrants, migrants, or refugees who maintain family relations across borders. These mostly qualitative articles address an array of today's most challenging issues confronting transnational families - negotiating immigration policies (Dominguez & Lubitow), sending international remittances (Johnson & Stoll), reuniting war-separated children (Luster, Qin, Bates, Johnson, & Rana), and maintaining intergenerational relationships (§enyiirekli & Detzner; Treas). These authors have been guided by varied theoretical perspectives, including social network, ambiguous loss, role strain, intergenerational solidarity and ambivalence, and life course theories. Common to all five articles is the underlying assumption that although transnational families are affected by both financial and emotional strains, they benefit from strong systems of social and family support through which they can maintain a sense of cultural and family identity. The article by Silvia Dominguez and Amy Lubitow titled "Transnational Ties, Poverty, and Identity: Latin American Immigrant Women in Public Housing" helps us to better understand the significance of transnational ties in the context of poverty. In this study, impoverished women utilized family connections across the border in order to escape domestic violence or when in need of a safe haven for their children during the summer months. By sending them across the border to live with relatives, transnational ties served as a protection strategy for the children who live in dangerous U.S. neighborhoods. The experience of poor urban mothers can be contrasted with the struggles of Sudanese men and boys in two separate articles represented here. We hope both these articles will help raise awareness about the plight of Sudanese families who are survivors of the North-South civil war. In the first article, we learn of Sudanese refugee men who serve in a "global breadwinner role," a useful term coined by authors Phyllis Johnson and Kathrin Stoll in their study, "Remittance Patterns of Southern Sudanese Refugee Men: Enacting the Global Breadwinner Role. …
|
2022-01-27T03:48:02.087Z
|
223,434,950 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3760/CMA.J.ISSN.1674-6090.2009.03.024",
"MAG": "3029105869",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
原发性甲状旁腺功能亢进(PHPT)是一种少见的内分泌功能紊乱性疾病,发病率约3～5/万,女性多见.该病可累及人体多个系统,临床表现多样,极易误诊漏诊.我科1995年至2008年共收治PHPT 11例,现报告如下。
|
2022-02-08T00:36:23.306Z
|
74,069,141 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.15373/2249555X/MAR2014/3",
"MAG": "2182770276",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Background: Metabolic syndrome (MetS) refers to a cluster of features conferring the risk for cardiovascular disease and type 2 diabetes mellitus. Considering the fact that the thyroid dysfunction is also associated with the risk for CVD, this study was undertaken to estimate the levels of thyrotropin stimulating hormone (TSH) in subjects with and without metabolic syndrome. Materials and Methods: The study population included 50 subjects with metabolic syndrome and 50 subjects without metabolic syndrome. Blood pressure and anthropometric measurements were measured in all the study subjects, following which a fasting blood sample was obtained for the estimation of fasting blood sugar (FBS), lipid profile and TSH. The data obtained was analyzed using SPSS software. AHA/NHLBI definition was used to define MetS. The values obtained were compared using student t test and correlated using Pearson correlation. Results: TSH levels were high among the subjects with MetS and it was statistically highly significant (<0.01). Pearson's product-moment correlation of TSH with age and the components of the MetS yielded a positive and highly significant (<0.01) correlation with age, FBS and waist circumference (WC). It also significantly correlated with triglyceride (TGL) (<0.05). The prevalence of hypothyroidism in MetS was 46% and the hyperthyroidism was 6%. Conclusion: High TSH was found to be associated with metabolic syndrome, suggesting that hypothyroid subjects are prone for cardiometaboilc risk.
|
2022-02-11T08:29:53.826Z
|
232,082,817 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4103/jeed.jeed_14_18",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Background: Self-medication (SM) is defined as the use of medicines by individuals to treat self-diagnosed conditions or symptoms without professional consultation. SM is rampant in countries with limited access to health care and lack of stringent regulations and patient education. Without adequate knowledge and awareness, SM may prove fatal. However, if practiced correctly, it can save time and money. The present study was conducted with an objective to compare the patterns of SM in first-year and final-year dental students, at a tertiary care dental teaching institute in Delhi. Materials and Methods: It was a quantitative, prospective, and descriptive cross-sectional study based on designed self-administered questionnaire, framed after consulting previous studies. Results: The data were summarized as the number and percentage in the form of tables, graphs, and pie chart. Google percentage calculator was employed to calculate percentage and generate charts for pictographic representation of our results. Statistical analysis was done using SPSS software version 19, and Chi-square test was applied to identify the level of significance among variables. Conclusions: SM is a regular practice by dental students and needs to be curbed at earliest. Such practice tends to influence their behavioral pattern of drug prescribing in future. There is a need to conduct regular continuing medical education and workshops to create awareness about risks and adverse consequences of SM to ensure rational and safe use of medicines including antibiotics. Committees should be constituted at hospital level to continuously monitor the dispensaries/pharmacy stores, to make sure that drugs are dispensed on authorized prescription. Dispensing personnel should be held accountable for every purchase made by the consumer.
|
2022-07-16T22:48:53.094Z
|
122,044,472 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1029/JB075I029P05767",
"MAG": "2053071543",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The inhomogeneous wave equation for a plane compressional wave propagating in a Voigt medium is solved to yield exact mathematical expressions for the medium's response to a unit impulse excitation pressure. The solutions obtained, which are Green's function of the medium, show the pulse-lengthening, attenuation, and oscillation properties of Voigt waves. It is shown that, unlike previously published solutions, particle velocities oscillate because of elastic recovery of the stressed medium.
|
2022-09-10T20:38:50.225Z
|
119,826,281 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1115/1.2910017",
"MAG": "1988990415",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The time integral of the local instantaneous conservation laws has been used as the starting point to write a subchannel model. The assumption of an ergodic stationary process has made possible further spatial integration of the resulting equations. The SIMPLER algorithm is adapted for the numerical solution. An adequate blockage model assures an overall momentum balance over the discretized cell elements. Comparison of the predictions of the proposed model with the experimental data confirms that it is capable of handling blockages of up to 90 percent of the flow area
|
2022-09-13T09:58:40.119Z
|
206,641,950 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/TCOMM.2010.05.080299",
"MAG": "1966874787",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Existing design methods for irregular Low-Density Parity-Check (LDPC) codes over the additive white Gaussian noise channel are based on using asymptotic analysis tools such as density evolution in an optimization process. Such a process is computationally expensive particularly when a large number of constituent variable node degrees are involved in the design. In this paper, we propose a systematic approach for the design of irregular LDPC codes. The proposed method, which is based on a pre-computed upper bound on the fraction of edges connected to variable nodes of degree 3, is considerably less complex than the conventional optimization approach. Through a number of examples, we demonstrate that using our method, ensembles with performance very close to those devised based on optimization, can be designed. In addition to having very good performance, the number of constituent variable node degrees in the designed ensembles is only three or four. This, in some cases, is much smaller than the corresponding number for optimization-based designs with similar performance.
|
2022-09-15T01:56:23.098Z
|
30,244,011 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1515/zna-2010-0312",
"MAG": "2026708374",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "HYBRID",
"url": "https://www.degruyter.com/document/doi/10.1515/zna-2010-0312/pdf"
}
|
This investigation deals with the influence of radiation on magnetohydrodynamic (MHD) and mass transfer flow over a porous stretching sheet. Attention has been particularly focused to the unsteadiness. The arising problems of velocity, temperature, and concentration fields are solved by a powerful analytic approach, namely, the homotopy analysis method (HAM). Velocity, temperature, and concentration fields are sketched for various embedded parameters and interpreted. Computations of skin friction coefficients, local Nusselt number, and mass transfer are developed and examined.
|
2022-12-15T12:15:19.621Z
|
6,109,716 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1074/JBC.M311616200",
"MAG": "2025949960",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Activation-induced deaminase (AID) is required for both immunoglobulin class switch recombination and somatic hypermutation. AID is known to deaminate cytidines in single-stranded DNA, but the relationship of this step to the class switch or somatic hypermutation processes is not entirely clear. We have studied the activity of a recombinant form of the mouse AID protein that was purified from a baculovirus expression system. We find that the length of the single-stranded DNA target is critical to the action of AID at the Cs positioned anywhere along the length of the DNA. The DNA sequence surrounding a given C influences AID deamination efficiency. AID preferentially deaminates Cs in the WRC motif, and additionally has a small but consistent preference for purine at the position after the WRC, thereby favoring WRCr (the lowercase r corresponds to the smaller impact on activity).
|
2022-12-20T17:22:20.984Z
|
168,724,958 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4236/CUS.2017.54025",
"MAG": "2774217776",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Regeneration movement is an irreplaceable necessity for Istanbul not only to
prevent the destructions of earthquake and improve physical quality, but also
to enhance the quality of life, reduce social vulnerability and maintain both
social and physical sustainability. In Turkey, the term of urban regeneration
has had different descriptions according to various agencies and stakeholders
since 1980s. While academicians evaluate the regeneration projects as planning
tools for having sustainable and high quality urban environments from
social, ecological and economic approaches, investors for instance justify that
they need more development rights and need to make more money to build
good condition buildings for having that kind of neighborhoods. Residents,
however, are the most important stakeholders to decide the future of the
neighborhood. This research aims to evaluate what the residents’ satisfaction
level, perceptions and expectations are about the conditions and the possible
urban regeneration movements in the neighborhood. 5 main headings are
specified as main indicators for the research and conducted by surveys and
interviews with current residents in the case of Atasehir, Barbaros Neighborhood
which is a new developing and attractive area for real estate investments
and urban regeneration projects in Istanbul. At the end of this research, it is
stated that residents are very aware of the content of urban regeneration at
practice level, and they believe in their neighborhood needs to regenerate for
several reasons. They, however, discredit the term about having environment
which is healthy and has high quality of life. They are just interested in the
economic returns of the projects, and they expect to be built high level income
housing to sell the prices out of the market.
|
2022-02-08T18:12:24.974Z
|
79,502,355 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.15844/PEDNEURBRIEFS-23-8-6",
"MAG": "2609170247",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The risk for adverse cardiac events in subjects between 3 and 20 years of age treated with methylphenidate or amphetamine salts for ADHD was determined in a retrospective study at University of Florida, Gainesville, FL.
|
2022-07-11T02:54:24.103Z
|
95,864,193 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1142/S0219633612500770",
"MAG": "2012979824",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The M05-class (M05 and M05-2X) and M06-class (M06, M06-2X, M06-HF, and M06-L) functionals, developed by Zhao and Truhlar, have shown better performance than popular older DFT functionals in obtaining accurate binding energies of noncovalent complexes. However, the reliability of these functionals for the structure and geometry of noncovalent systems was seldom assessed. Here, using the MP2/aug-cc-pVTZ values as a benchmark, we assessed the performance of the M05-class and M06-class functionals for the structure and geometry of the hydrogen-bonded and halogen-bonded complexes. The results clearly show that the M05, M06 and M06L functionals totally fail to predict the structure of the hydrogen-bonded complex formed between glycine and carbonic acid whereas the M05-2X, M06-2X, M06-HF, and even B3LYP succeed. For the geometries of a series of halogen-bonded complexes, it is found that the M05-2X functional performs slightly better than the M06-2X and M06-HF functionals and much better than the M05, M06 and M06-L functionals on average. Based on these tests, we concluded that the M05, M06 and M06-L functionals are not good for the study of the structure and geometry of the hydrogen-bonded and halogen-bonded complexes and the density functional M05-2X is the best choice. In addition, we have also assessed the integration grid errors arising from the numerical integration of these functionals for the structure and geometry of the hydrogen-bonded and halogen-bonded complexes.
|
2022-08-29T01:07:11Z
|
253,287,070 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1210/jendso/bvac150.471",
"MAG": null,
"PubMedCentral": "9629108"
},
"license": null,
"status": "GREEN",
"url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9629108"
}
|
Abstract Background Autosomal dominant hereditary multiple osteochondromas is a rare genetic disorder with variable clinical manifestations. We present the case of a patient misdiagnosed with Paget's disease of bone found to have hereditary multiple osteochondromas. Clinical Case We present a 55-year-old male with history of chronic back and hip pain who presented to endocrinology clinic for evaluation of Paget's disease of bone. He was diagnosed with Paget's disease at age 16 after a bike accident resulting in knee pain where a "knot" was removed from his knee. He reported multiple "knots" in bones throughout adulthood but never sought treatment. He had history of elevated alkaline phosphatase on prior chemistries. He developed debilitating back, hip, and thigh pain resulting in immobility and suffered vertebral osteomyelitis from MRSA requiring laminectomy at age 52. On physical exam, massive maxillary and mandibular tori were noted along with bilateral cataracts and decreased muscle strength in upper and lower extremities. He underwent evaluation by oral surgery for extensive tooth decay and was recommended for extraction of teeth #12, 14, 15, and 17 with restorative needs for teeth #2, 4, 5, 13, 28, 30, 32. Labs notable for serum calcium 10.1 (ref: 8.4-10.5 mg/dl), phosphorus 4.2 (ref: 2.3-4.7 mg/dl), magnesium 1.8 (ref: 1.6-2.6mg/dl), PTH 34 (ref: 16-77 pg/ml), 25-OH Vit D 28 (ref: 25-80 ng/ml), 1,25 dihydroxyvitamin D 45.9 (ref: 19.9-79.3pg/ml), alkaline phosphatase 199 (ref: 40-150 unit/L), bone-specific alkaline phosphatase 52.5 (ref: 6.5 - 20.1 mcg/L). 24-hr urine calcium 0.06 g/24hr (ref: 0.04-0.35) from an 850ml urine volume. Procollagen type 1 n-terminal propeptide 179 (ref 22-105 UG/L). Prior MRI right hip showed "abnormal appearance of pelvic bony ring and proximal femurs with heterogenous marrow signal and cortical thickening suspicious for Paget's disease", as well as a 1.2cm circumscribed cystic focus within proximal right femoral diaphysis. Prior bone scan demonstrated diffusely uptake in pelvis, uptake in proximal right femur, focally intense uptake in L5 vertebrae. Plain film imaging demonstrated severe diffuse degenerative changes in cervical, thoracic and lumbar vertebrae and sessile osteochondromas arising from both scapulae, mild thoracic levoscoliosis. Genetic testing demonstrated loss-of-function mutation in the EXT-1 gene, diagnostic of hereditary multiple osteochondromas. Currently, there are no FDA-approved treatments for osteochondromas though studies involving biologic therapy are ongoing. This patient was referred to orthopedic oncology and OMFS for dental extraction and decision for conservative treatment with observation. Conclusion This case demonstrates how the rare entity of hereditary multiple osteochondromas can have variable clinical presentations leading to its misdiagnosis and highlights the need for ongoing research into non-surgical treatment options. Presentation: Saturday, June 11, 2022 1:00 p.m. - 3:00 p.m., Monday, June 13, 2022 12:36 p.m. - 12:41 p.m.
|
2022-12-10T09:40:31.468Z
|
5,034,135 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/APEC.2018.8341059",
"MAG": "2798920204",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
When connected to distribution networks with distorted grid voltages, inverters can easily produce high levels of current harmonics. When these networks have high interface impedances, the control schemes designed to mitigate these harmonics can easily become destabilized. This paper demonstrates a multirate controller that can adapatively generate harmonic currents as needed at frequencies up to nearly half the sample rate. The controller is shown to be stable even with purely inductive grid impedances as high as 10% per unit. Both simulation and experimental results are presented.
|
2022-12-16T06:54:51.002Z
|
40,595,119 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3892/or.2013.2603",
"MAG": "1998731742",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://www.spandidos-publications.com/or/30/3/1380/download"
}
|
Chemokine receptors CCR6 and CCR7 have been reported to play important roles in T cell migration and organ-specific metastasis of various tumors. In the present study, we evaluated the expression and clinical significance of CCR6, CCR7, their ligands and CD4+CD25+Foxp3+ regulatory T cells in laryngeal squamous cell carcinoma (LSCC) and metastatic lymph nodes (LNs). The expression of CCR6, CCR7 and their ligands mRNA (CCL20, CCL19/CCL21) as well as the CCR6 and CCR7 proteins were detected by real-time RT-PCR and immunohistochemistry (IHC), respectively. Flow cytometry was used to investigate the percentage of CD4+CD25+Foxp3+ regulatory T cells (Tregs) in peripheral blood mononuclear cells (PBMCs). Furthermore, a number of cytokines, including interleukin (IL)-2, IL-4, IL-10, IL-12p70, interferon (IFN)-γ and transforming growth factor (TGF)-β1 were detected by ELISA. The results showed that CCR6 and CCR7 were expressed in tumors in situ, metastatic LNs and CD4+CD25+Foxp3+ Tregs. It was hypothesized that the expression profile of CCR6, CCR7 and the proliferation of CD4+CD25+Foxp3+ Tregs affected the process of LN metastasis in LSCC patients. Therefore, the increased percentage of the Foxp3+ Tregs and the upregulation of Foxp3 expression on CCR6+ Tregs in LSCC patients may have accounted for the downregulation of antitumor immunity in these patients, which could be valuable for assessment of prognosis in LSCC treatment.
|
2022-12-14T20:21:11.061Z
|
15,521,032 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/GSIS.2009.5408255",
"MAG": "2152780532",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The grain yield time series is a non-steady time series that has the definite dynamic tendency and stronger random fluctuation. Therefore, we first use the grey GM(1, 1) model to obtain the tendency term, and then the generalized trigonometric model is used to catch the periodic phenomenon from the data for improving forecasting accuracy. The grey model with the trigonometric residual modification technique, which is named trigonometric grey prediction model, has combined the advantages of grey model and the trigonometric model, it has overcome the influence by data fluctuation to precision of forecasting. At last, the validity and applicability of the model are demonstrated by a simulation of annual grain yield.
|
2022-02-13T01:50:54.463Z
|
94,620,972 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/10588330208951213",
"MAG": "1963757540",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract Solid fragments of explosives in soil are common in explosives testing and training areas. In this study we initially sieved the upper 6 in of contaminated soil through a 3-mm mesh, and found 2,4,6-trinitrotoluene (TNT) fragments. These contributed to an estimated concentration of 1.7 kg per cubic yard soil, or for 2000 ppm TNT in the soil. Most of the fragments ranged 4 mm to 10 mm diameter in size, but explosives particles weighing up to 56 g (about 4 cm diameter) were frequently observed. An acetone pretreatment/composting system was then demonstrated at field scale. The amount of acetone required for a TNT-dissolving slurry process was controlled by the viscosity of the soil/acetone mix rather than the TNT dissolution rate. The amount needed was estimated at about 55 gallons acetone per cubic yard soil. Smaller, 5- to 10-mm-diameter fragments went into solution in less than 15 min at a mixer speed of 36 rpm, with a minimum of 2 g TNT going into solution per 30 min for the larger chunks. The slurries were then mixed with compost starting materials and composted in a vented 1 yd3 container. After 34 days incubation time TNT was below the site-specific regulatory threshold of 44 ppm. TNT metabolites and acetone were also below their regulatory thresholds established for the site.
|
2022-08-31T07:59:41.178Z
|
14,740,368 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/COMPSAC.2016.93",
"MAG": "2515280630",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The Internet Security Threat Report by Symantec announced that the number of data breaches increased 23 percent in 2014 and the causes by theft or loss of devices reached to 21 percent. Carrying mobile devices with business data and private information is indispensable for human's social activities nowadays and unexpected data breach is one of the severe ongoing issues in cyber security. In this paper, we propose a concealed file system adapted for mobile devices based on GPS (Global Positioning System) information which is only mountable in the designated area. Differs from conventional encryption technologies, the proposed file system can be completely isolated from the viruses and attacks outside the designated area. Moreover, instead of the GPS information of the designated area, the encrypted hash value will be stored in mobile devices for the privacy concerns. We statistically analyzed the GPS information logged in our lab and defined an algorithm for deciding the designated area without leaking the GPS information. Based on the algorithm, we evaluated the proposed file system using Veracrypt by adding the hash of GPS information indicating the designated area as one of the attributes for mounting authentication. As a result, we confirmed that the proposed file system was mounted with about 91% success rate within average in the designated area even with noise interference.
|
2022-09-06T08:18:59.102Z
|
129,260,532 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5209/REV_CGIB.1984.V9.2739",
"MAG": "1880215886",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The present work represents a preliminary synthesis of ali the trilobites quoted in the Spanisl-i areas of the Hesperian Massif so far, The main findings are analyzed from a chronostratigraphical and geographical point of view, and the differences between the successive trilobite associations are shown, as well as their significance from a palaeobiogeographical point of view. The utility of these organisms for the biostratigraphical characterization of deposits belonging to several Departamento de Paleontologia e Instituto de Geologia Economica (CSIC * UCM), Facultad de Ciencias Geologicas, Universidad Complutense, Ciudad Universitaria. 28040 - Madrid. 267 epochs and the problems derived of their correlation with other areas are also studied.
|
2022-09-16T09:19:31.413Z
|
204,908,287 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/acsami.9b13944",
"MAG": "2982113148",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://www.osti.gov/biblio/1576978"
}
|
The efficiency of a thermophotovoltaic (TPV) system depends critically upon the spectral selectivity and stability of an emitter, which may operate most effectively at temperatures in excess of 1000 °C. We computationally design and experimentally demonstrate a novel selective emitter design based on multilayer nanostructures, robust to off-normal emission angles. A computational search of the material and temperature compatibility space of simple emitter designs motivates new material classes and identifies several promising multilayer nanostructure designs for both TPV absorber and emitter applications. One such structure, comprising a thin (<100 nm) tunable TixAl1-xN (TiAlN) absorber and refractory oxide Bragg reflector is grown on W metal foil. In agreement with simulations, the emitter achieves record spectral efficiency (43.4%) and power density (3.6 W/cm2) for an emitter with at least 1 h of high temperature (>800 °C) operation.
|
2022-12-08T23:42:25.738Z
|
5,237,670 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/026839629801300302",
"MAG": "1965132910",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Electronic commerce is causing fundamental changes in the insurance sector. Inherent opportunities of this innovative sales channel are driving the development of a new customer relationship paradigm, development of new products, pursuit of low cost ‘self service’ strategies, and emergence of ‘virtual brokers’. The Australian insurance sector is well positioned to take advantage of electronic commerce due to the high level of PC penetration, high Internet usage, and extensive broadband infrastructure. The perception is that the Australian insurance sector is meeting these challenges. Surprisingly, despite the emergence of electronic commerce as a ‘hot topic’ in the information technology and insurance sector literature, little empirical research has been reported. Much of the extant literature can be criticized as being too generic and superficial. It is argued that until research is focused on specific aspects of electronic commerce, we will fail to capture meaningful insights. The aim of this research project is to develop a research framework appropriate for electronic commerce, research and to apply it to a specific sector (insurance), in a specific geographical region (Australia), using a specific electronic commerce, medium (Internet), for a specific purpose (business to consumer sale of risk products). The research objective is to discover which Australian insurance companies are using electronic commerce for what. The survey found that of the 21 largest Australian insurance companies only 18 have web sites. These sites are mainly used for promotional purposes and not for directly generating sales. Only six companies offer customer-specific pricing of their products. And of these, only four companies sell any of their products over the Internet. Paradoxically, despite pressing business drivers in the insurance sector and a favourable electronic commerce environment in Australia, these findings demonstrate a significant gap between appreciation of the importance of electronic commerce and realization of commercial potential. Whilst most Australian insurance companies are well aware of the special importance of electronic commerce, many fail to take full advantage. Although further qualitative research is recommended to understand why this is so, it is clear that a significant gap remains between the technical capabilities of electronic commerce and actual practice in the Australian insurance sector.
|
2022-12-10T14:48:00.171Z
|
158,548,913 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.25038/AM.V0I10.138",
"MAG": "2801481888",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper deals with Internet memes as a form of viral content that spreads via the network varying a basic concept while constructing and deconstructing different identities. If memes are understood as a discursive field in the completely new world of social media, in which different groups, their attitudes, ideologies and interests are represented more clearly and more directly than ever before through the appropriation of popular contents and images, then this form of viral content can be also viewed as a space of resistance and criticism in which identities are decentralized and ready for change.
|
2022-12-15T13:09:41.813Z
|
121,855,946 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1119/1.2350661",
"MAG": "2057441411",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this account of Cerenkov radiation, the optical analogue of the 'supersonic bang,' great emphasis is laid on the underlying physical principles of the effect. The historical introduction is followed by a qualitative account of the basic mechanism of the generation of light by the passage of fast charged particles through homogeneous transparent media. After a discussion of the relationship of Cerenkov radiation to other processes connected with the interaction of fast particles with matter, the article turns to the practical applications of Cerenkov detectors and counters in the fields of cosmic-ray and high-energy physics. In conclusion, the author describes some interesting experiments carried out by his colleagues and himself on light flashes from the night sky.
|
2022-12-25T19:48:57.636Z
|
15,450,021 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/NAR/25.4.764",
"MAG": "2057542364",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Two types of enzyme utilizing light from the blue and near-UV spectral range (320-520 nm) are known to have related primary structures: DNA photolyase, which repairs UV-induced DNA damage in a light-dependent manner, and the blue light photoreceptor of plants, which mediates light-dependent regulation of seedling development. Cyclobutane pyrimidine dimers (CPDs) and pyrimidine (6-4) pyrimidone photoproducts [(6-4)photoproducts] are the two major photoproducts produced in DNA by UV irradiation. Two types of photolyases have been identified, one specific for CPDs (CPD photolyase) and another specific for (6-4)photoproducts [(6-4)photolyase]. (6-4)Photolyase activity was first found in Drosophila melanogaster and to date this gene has been cloned only from this organism. The deduced amino acid sequence of the cloned gene shows that (6-4)photolyase is a member of the CPD photolyase/blue light photoreceptor family. Both CPD photolyase and blue light photoreceptor are flavoproteins and bound flavin adenine dinucleotides (FADs) are essential for their catalytic activity. Here we report isolation of a Xenopus laevis(6-4)photolyase gene and show that the (6-4)photolyase binds non- covalently to stoichiometric amounts of FAD. This is the first indication of FAD as the chromophore of (6-4)photolyase.
|
2022-12-23T02:03:33.364Z
|
635,293 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1749-6632.1992.tb51645.x",
"MAG": "1995123717",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Tissue-type plasminogen activator (tPA) is a serine protease, which is involved in the process of fibrinolysis. This enzyme activates plasminogen into plasmin, which causes fibrin degradation in hemostatic clots. The activation of the proenzyme plasminogen is normally slow, but is strongly enhanced by the binding of tPA and plasminogen to fibrin.'Y2 The fibrin specificity of tPA has made it a useful tool in the treatment of thrombotic events during the last few years. Since the widespread availability of recombinant tPA (rtPA) a number of clinical trials have demonstrated that the enzyme is a potent drug in the treatment of myocardial inhtions.j.4 Reperfusion rates of about 60-80% of occluded arteries occurred after administering 40-100 mg of rtPA over a period of 1-3 hours. Although rtPA has advantages over other thrombolytic agents (streptokinase and APSAC), such as the larger fibrin specificity and little or no immunogenic response, a disadvantage of the use of tPA might be its fast clearance from the blood stream, predominantly by the liver. This overview presents a summary and a discussion of our studies on the mechanism of tPA ~ lea rance~-~ and the relevant literature. It is anticipated that knowledge on the liver uptake will either result in new tPA mutants with a prolonged circulation time or in the development of inhibitors of tPA clearance.
|
2022-12-23T20:51:34.935Z
|
251,377,294 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/nano12152684",
"MAG": null,
"PubMedCentral": "9370464"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2079-4991/12/15/2684/pdf?version=1660150757"
}
|
Ultra-sensitive and responsive humidity sensors were fabricated by deposition of graphene oxide (GO) on laser-induced graphene (LIG) electrodes fabricated by a low-cost visible laser scribing tool. The effects of GO layer thickness and electrode geometry were investigated. Sensors comprising 0.33 mg/mL GO drop-deposited on spiral LIG electrodes exhibited high sensitivity up to 1800 pF/% RH at 22 °C, which is higher than previously reported LIG/GO sensors. The high performance was ascribed to the high density of the hydroxyl groups of GO, promoted by post-synthesis sonication treatment, resulting in high water physisorption rates. As a result, the sensors also displayed good stability and short response/recovery times across a wide tested range of 0–97% RH. The fabricated sensors were benchmarked against commercial humidity sensors and displayed comparable performance and stability. Finally, the sensors were integrated with a near-field communication tag to function as a wireless, battery-less humidity sensor platform for easy read-out of environmental humidity values using smartphones.
|
2022-12-30T00:59:37.991Z
|
226,544,804 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1332/147867320x15986395241531",
"MAG": "3089268096",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://rucforsk.ruc.dk/ws/files/75688561/JPSS_D_20_00071_R1_1.pdf"
}
|
In the Nordic welfare states, social innovation is currently seen as key to improving and renewing services and sustainable products, to changing and empowering people’s lives, to enhancing public services and to encouraging private‐public‐civil collaborations. In
this article, I provide insights into the psychosocial fabric of this current development, pointing out how identification, idealisation and shame become descriptive of the psychosocial landscape in social enterprises. Social enterprises invest in creating both social and economic value as
well as reinvesting their profits for the good of their enterprise, staff, volunteers and the local community. Through an examination of case studies, I illustrate how managers and staff identify with and idealise their social innovative missions, but find it difficult to fulfil their aspirations
in the face of (neoliberal) societal and organisational contexts and conditions.
|
2022-01-27T01:55:20.868Z
|
220,088,044 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1126/science.1222944",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The Royal Observatory marks the upcoming transit of Venus with a small exhibition on our efforts to grasp the vast distances of the universe. The Royal Observatory marks the upcoming transit of Venus with a small exhibition on our efforts to grasp the vast distances of the universe.
|
2022-01-27T04:54:18.282Z
|
234,303,676 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.31258/JES.5.1.P.104-118",
"MAG": "3124922682",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This research was motivated by the lack of teachers in developing learning tools causing students' mathematical understanding is still in the low category. The learning devices used in schools have not trained students' mathematical understanding skills. The aim of this study is to produce guided discovery-based mathematics learning tools to facilitate mathematical comprehension skills that meet the validity and practicality requirements. This type of research was a development research using the ADDIE model. The instruments used in this study were the syllabus validation instrument, lesson plans, student worksheet and practicality using student response questionnaires. Based on the results of data analysis, it shows that the guided discovery-based mathematics learning device is a valid category. The results of the validation of the syllabus, RPP and LKPD showed that the category was very valid with the value sequentially obtaining a score of 92.5%; 95%; and 94.87%. The results of the practicality data analysis in small group trials showed a very practical category with a score of 93.64%. It can be concluded that the learning tools developed are feasible and practical to use in the learning process.
|
2022-02-28T14:09:28.967Z
|
40,288,966 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1365-4632.2004.01558.x",
"MAG": "1974632353",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
has created considerable interest, as it affected 14 individuals from three generations of one family. This genetic disease often runs in families and the mode of inheritance is usually, with a few exceptions, autosomal recessive. 2 Contrary to that, the inheritance was mostly dominant in the described family. One explanation might be consanguinity in some former generations. However, the family tree is nonconclusive. Typical features of EV are widespread plane warts and pityriasis versicolor-like lesions with a highly characteristic cytopathic effect: clarification of epidermal cells starting from the suprabasal layer; more pronounced in the upper layers. In the described case such lesions appeared at the age of 5 years and carcinoma developed at the age of 27 years. Malignancies and premalignancies (actinic keratoses, Bowen’s type carcinoma in situ ) originating from benign lesions usually start to appear in the third to fourth decades, i.e. 20– 30 years after the onset of the disease. 3 Thus the malignant transformation is a very long-lasting process, similar to the progression of cervical intraepithelial neoplasia into invasive tumors. One characteristic is preferential localization of malignancies at the sun-exposed areas as a result of the immunosuppressive and DNA-damaging effects of ultraviolet irradiation. In spite of the almost generalized skin involvement, genital and buccal mucosa are not involved. The general condition of the patients remains satisfactory. The profound defect of cell-mediated immunity (CMI) is specific towards the causative viruses. The immunotolerance, i.e. inability to recognize one’s HPVs and reject the viralinduced lesions, leads to a life-long disease. Causative HPVs differ from all other (almost 100) characterized cutaneous and genital HPVs, and are referred to as EV-specific viruses. Among more than 20 known EV-specific HPVs, i.e. HPVs found in lesions of EV, 4–6 only some have oncogenic potential, mainly HPV5 and 8, and much more rarely HPV14, 17, 20 and 47. However, in EV cancers diverse EV HPVs may be detected in addition to HPV5 and 8. Moreover, a remarkable heterogeneity of oncogenic EV HPVs within the same HPV type is a frequent phenomenon. 5,7
|
2022-09-07T10:12:58.530Z
|
6,085,402 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ARITH.2009.34",
"MAG": "2166628680",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We introduce a novel left-to-right leading digit first dual recoding of an operand for the purpose of designing the squaring operation on that operand. Our dual recoding yields an array of non-negative partial squares of size essentially one half that of a comparable multiplier partial product array for both radix-4 and radix-8 designs. For radix-8 design the 128-bit square of a 64-bit operand can be obtained from a consolidated partial square array of just 11 rows. We describe advantages of our left-to-right recoding compared to a previous right-to-left Booth-folding encoding applicable to radix-4. We also show simplifications available to the designs of a rounded floating point square operation and to a low precision approximate square.
|
2022-09-15T07:02:18.146Z
|
39,041,333 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1161/STR.35.6.1268",
"MAG": "2132159169",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Stroke and dementia were implicitly associated by the advent of the concept of multi-infarct dementia, but it was Tatemichi et al1 who put this in temporal context and brought it to popular attention by observing a 26.3% dementia incidence 3 months after hospitalization for stroke. Several subsequent studies largely confirmed Tatemichi’s work but gave incidence estimates for poststroke dementia from 6% to 32%,2,3 with most studies producing estimates toward the upper end of this range. As Ivan et al4 point out, these works are potentially inaccurate for several reasons, including cross-sectional study design, the use of hospital-based cohorts with the risk of selection bias, lack of controls, and no (or imperfect) exclusion of previous dementia, to which should be added the effect of the diagnostic criteria used.
What is remarkable about the data from Ivan et al is that it took ≈10 years for 19.3% of the cases of dementia to develop, a level that in most other studies …
|
2022-07-07T12:49:27.507Z
|
24,454,340 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/01.mca.0000071769.74379.49",
"MAG": "2331212636",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Background It is known that blood and plasma viscosities are associated with clinical manifestations of atherosclerosis, though evidence is not conclusive particularly in women. Objective To verify whether hematocrit and blood and plasma viscosities are independently associated with carotid atherosclerosis and whether their measurement can improve the definition of the global coronary heart disease (CHD) risk. Method Eight hundred and ninety‐two participants in a cardiovascular disease prevention campaign were examined with regard to conventional CHD risk factors (age, blood pressure, lipids, glucose, body mass index, waist/hip ratio, cigarette smoking and diabetes), hematocrit and blood and plasma viscosities. According to the degree of carotid atherosclerosis, investigated by echo‐Doppler, participants were divided in three groups: those without atherosclerosis, those with a low degree of atherosclerosis and those with a high degree of atherosclerosis. Results In men, age, blood pressure, intima‐media thickness (IMT), hematocrit (47.4± 3.7%, 47.8± 3.7%, 48.4 ± 3.7%, P < 0.05) and blood viscosity (4.69± 0.51 cP, 4.77± 0.55 cP, 4.82 ±0.51 cP, P = 0.05) increased with increasing degree of carotid atherosclerosis. In women, age, blood pressure, total cholesterol and low‐density lipoprotein‐ cholesterol, IMT and plasma viscosity (1.42 ± 0.12 cP, 1.44± 0.11 cP, 1.46± 0.13 cP, P < 0.05) increased with increasing carotid score. Analysis of covariance (ANCOVA) showed that after adjusting for hematocrit, blood viscosity was no longer different in the three groups. In discriminant analysis, hematocrit, among the hemorheological variables investigated, was independently associated with carotid score in men (F = 3.66, P < 0.05). Neither hematocrit nor blood and plasma viscosities were significantly associated with carotid score in women. Conclusion These findings suggest that in men, both hematocrit and blood viscosity are related to carotid atherosclerosis but hematocrit would appear to have an independent effect over and above that mediated by viscosity. Coron Artery Dis 14:279‐284 © 2003 Lippincott Williams & Wilkins.
|
2022-09-10T22:32:51.286Z
|
52,291,054 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/TMSCS.2017.2748122",
"MAG": "2752212539",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
SpiNNaker (Spiking Neural Network Architecture) is a specialized computing engine, intended for real-time simulation of neural systems. It consists of a mesh of 240x240 nodes, each containing 18 ARM9 processors: over a million cores, communicating via a bespoke network. Ultimately, the machine will support the simulation of up to a billion neurons in real time, allowing simulation experiments to be taken to hitherto unattainable scales. The architecture achieves this by ignoring three of the axioms of computer design: the communication fabric is non-deterministic; there is no global core synchronisation, and the system state—held in distributed memory—is not coherent. Time models itself: there is no notion of computed simulation time—wallclock time is simulation time. Whilst these design decisions are orthogonal to conventional wisdom, they bring the engine behavior closer to its intended simulation target—neural systems. We describe how SpiNNaker simulates large neural ensembles; we provide performance figures and outline some failure mechanisms. SpiNNaker simulation time scales 1:1 with wallclock time at least up to nine million synaptic connections on a 768 core subsystem (∼1400th of the full system) to accurately produce logically predicted results.
|
2022-09-15T23:41:37.027Z
|
237,699,130 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/EN14154409",
"MAG": "3185664488",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Electrolyte stability can be improved by incorporating complexing agents that bind key decomposition intermediates and slow down decomposition. We show that hexamethyl-phosphoramide (HMPA) extends both the thermal stability threshold of sodium hexafluorophosphate (NaPF6) in dimethoxyethane (DME) electrolyte and the cycle life of double-layer capacitors. HMPA forms a stable complex with PF5, an intermediate in PF6 anion thermal degradation. Unbound, this intermediate leads to autocatalytic degradation of the electrolyte solution. The results of electrochemical impedance spectroscopy (EIS) and galvanostatic cycling measurements show large changes in the cell without the presence of HMPA at higher temperatures (≥60 °C). Fourier transform infrared spectroscopy (FTIR) on the liquid and gas phase of the electrolyte shows without HMPA the formation of measurable amounts of PF5 and HF. The complimentary results of these measurements proved the usefulness of using Lewis bases such as HMPA to inhibit the degradation of the electrolyte solution at elevated temperatures and potentially lead to improve cycle life of a nonaqueous capacitor. The results showed a large increase in capacitance retention during cycling (72% retention after 750,000 cycles). The results also provide evidence of major decomposition processes (0% capacitance retention after 100,000 cycles) that take place at higher temperatures without the additive of a thermal stability additive such as HMPA.
|
2022-12-02T11:32:25.759Z
|
37,409,731 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1136/bmj.2.4532.788",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc2056107?pdf=render"
}
|
At a meeting of the Manchester Medical Society on Oct. 1 Mr. W. F. NICHOLSON, reading a paper on this subject, said that bronchial obstruction with secondary infection was the common cause of lung abscess. In normal health the cilia lining the bronchial tree kept the air passages free from organisms and debris. When ciliary action was impaired by trauma, infection, or growth, coughing was effective in preventing bronchial obstruction. When coughing was embarrassed by pain or anaesthesia or tenacious secretion, bronchial obstruction might occur. An abscess due to bronchial embolism was peripheral in the lung, though it might not present on the costal surface. Because the subapical segment of the upper lobe and the apical segment of the lower lobe contained the most dependent bronchi in the lateral and supine positions respectively, these segments were most frequently,affected, and consequently most inhalation abscesses presented on the costal surface of the lung corresponding to these segments. The upper-lobe abscess was common after operations on the upper respiratory tract, in which a lateral position was usually emplbyed in the immediate postoperative period. Lower-lobe abscess was often due to abdominal operations, which were associated with a supine or Fowler's position. A putrid lung abscess was frequently undiagnosed because it was still not widely known that such an abscess could exist without foul sputum. When the abscess ruptured into the bronchial tree sputum would be present; but even before this happened there might be fetid breath. Treatment was by drainage, either bronchial (postural) or external (by operation). In either case location of the lesion must be exact if treatment was to be rational. The responsibility of the physician in these cases was heavy. If he delayed external drainage, in many cases the disease spread to a diffuse suppurative pneumonia of a lobe, which would eventually require a lobectomy. Moreover, the immediate mortality of conservative treatment was considerable. Only by sharing the responsibility with a surgeon from the beginning could drainage be instituted promptly in cases which did not respond to medical measures. Chemotherapy and antibiotics were of value, but did not replace drainage. Bronchoscopy was of value in locating the broncho-pulmonary segment of the abscess, in improving bronchial drainage, and in excluding a foreign body or growth; as a curative measure it was of little more value than postural drainage. Surgical drainage would decrease mortality and morbidity.
|
2022-12-10T09:46:49.256Z
|
62,773,232 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/i-smac.2017.8058370",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Many of the people around us forget to take medication on time. The proposed model of smart medical box is a single board computer based assistive device for people who suffer with short term memory loss. It is an alarm based device that helps in reminding patients about their medication. The use of Internet of Things (IoT) concepts and health sensing technologies make diagnosis easier and convenient for the doctors as well as the patients [1]. This paper presents an overview of an assistive device for monitoring non-compliance of medication by providing a single platform and a closed loop connection between patients, doctors, and pharmacies. This work gives insight into mechanical design, system architecture and design of android application, information security and integrating the physical system to cloud. The architecture used is a secure one as it uses end-to-end encryption for sending sensor data [2]. This device helps in maintaining one-time medication to the patients, and helps increasing the life expectancy.
|
2022-12-11T08:49:28.481Z
|
95,816,354 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2298/CICEQ0502074C",
"MAG": "2015648237",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The result of the synthesis and investigation of FTIR spectra of some dextran sulphates and their sodium (Na) salts are presented. A synthesis was conducted (under different reaction parameters) of esters with various degrees of esterification (from 1.0 to 2.3). FTIR investigations were performed on sulphates of low and high molecular hydrogenated dextrans of various molecular masses (Mw of 5000, 7000, 8000, 40000 and 500000). Particular care was taken to determine the degree of linearity of the synthesized dextran sulphates, the conformation of glucopyranosyl units and the way the sulpho groups and the water were bonded in their structures.
|
2022-12-18T09:41:05.059Z
|
30,111,730 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICMREE.2011.5930731",
"MAG": "1970209175",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Based on the traditional strategic model of metropolitan development and the theory of circular economy, we proposed a strategic model for metropolitan circular economic development. This model includes three components: the spatial structural strategic model (circular economic growth pole model, circular economic pole-axis development model, circular economic network development model and circular economic circle spacial structure model), the advantage-oriented strategic model, and the technology innovation strategic model. We applied our model to the Jinan metropolitan area to create circular economic development plans.
|
2022-02-12T12:56:20.710Z
|
59,576,704 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.14419/IJET.V4I1.3936",
"MAG": "2048298854",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In a highly competitive environment, cost reduction and optimization of the supply chain are more than ever a strategic issue for companies. In this sense, lean manufacturing is a lever that allows the company to continuously reduce the time required for the transformation of raw materials into finished products, eliminating waste and with the aim to meet the growing and diverse needs of these customers. In this paper, it based on the latest studies in this field in order to highlight the relationship between supply chain and lean manufacturing at reducing costs, eliminating waste and non-value added. Then it highlights the impact of lean manufacturing on the reactivity of the supply chain through inventory reduction, cycle time and flow acceleration. Finally, it presents the role and expectations of the supplier in the context of the merger Lean Manufacturing and Supply Chain. This research has enabled to understand the impact of lean manufacturing concepts on supply chain strategies.
|
2022-09-08T10:16:28.250Z
|
24,233,230 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1001/ARCHPSYC.1997.01830140031005",
"MAG": "2158322458",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Bonnie reminds us of the heritage and limitations of human subjects research. He points out that over the years, the protection of human subjects in research has enjoyed progress, experienced false starts, and endured inflated expectations. Both he and Elliott call attention to the fact that IRB review rarely probes how researchers propose to deal with impairments to subjects' decision-making capacities. We agree to IRBs should be encouraged to rethink their roles. But, as Bonnie argues, this requires a systematic review of the roles and functions of IRB rather than ad hoc adjustments by individual institutional IRBs. His proposal that IRBs should be encouraged to be more vigilant and through in their monitoring of research is sound, especially if the subjects are vulnerable or the research is risky. A strength of Bonnie's review is that it suggests both specific ways to test competency and a range of options for IRBs to ensure that vulnerable subjects are protected from overzealous or overreaching researchers. His historical review and normative proposals are objective, balanced, and thoughtful. Elliott's critique seems to single out psychiatric research with depressed patients as a special problem area. Although his title emphasizes severely depressed patients, he sometimes appears to neglect the fact that depression ranges across a spectrum from mild to severe. Elliott's point is well taken that severely depressed patients who are clearly incompetent should not, unless proper safeguards are provided, be enrolled in research. But his analysis falters because his position does not in the end respect personal autonomy.
|
2022-12-09T15:16:22.986Z
|
199,020,046 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2312/CGVC.20181206",
"MAG": "2896274604",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We introduce Shadow Retargeting which maps real shadow appearance to virtual shadows given a corresponding deformation of scene geometry, such that appearance is seamlessly maintained. By performing virtual shadow reconstruction from un-occluded real shadow samples observed in the camera frame, we recover the deformed shadow appearance efficiently. Our method uses geometry priors for the shadow casting object and a planar receiver surface. Inspired by image retargeting approaches [VTP* 10] we describe a novel local search strategy, steered by importance based deformed shadow estimation. Results are presented on a range of objects, deformations and illumination conditions in real-time Augmented Reality (AR) on a mobile device. We demonstrate the practical application of the method in generating otherwise laborious in-betweening frames for 3D printed stop motion animation.
|
2022-12-12T15:01:53.080Z
|
131,067,009 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/00167617708728976",
"MAG": "2154234622",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract In the Lake Frome area of South Australia there is a sedimentary sequence of non‐marine (or possibly distant marginal marine) pale‐green to grey, fine elastics and carbonates (Namba Formation). The base of these deposits is Medial Miocene in age and they are overlain unconformably by Pleistocene (and ? Pliocene) sediments. The Miocene sequence is equivalent to the Etadunna Formation of the Lake Eyre Basin, and the clay mineralogy is similar. Combining evidence from mineralogy, palynology, and vertebrate palaeontology, a warm high‐rainfall climate operating on a subdued topography is indicated for the lower part of the Miocene Lake Frome sequence. This caused the illite‐chlorite‐kaolinite suite of the largely Precambrian provenance to be transformed to smectite and randomly‐interstratified clay. A palygorskite‐dolomite assemblage accumulated in alkaline lakes of extreme marginal marine situation during periods of seasonal dry intervals superposed on the previous climate. A change to illite‐dominat...
|
2022-12-12T16:45:24.017Z
|
21,438,344 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/BSD.0b013e31811513a4",
"MAG": "2054265226",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Study Design A study of spine biomechanics in a cadaver model. Objective To quantify motion in multiple axes created by transfer methods from stretcher to operating table in the prone position in a cervical global instability model. Summary of the Background Data Patients with an unstable cervical spine remain at high risk for further secondary injury until their spine is adequately surgically stabilized. Previous studies have revealed that collars have significant, but limited benefit in preventing cervical motion when manually transferring patients. The literature proposes multiple methods of patient transfer, although no one method has been universally adopted. To date, no study has effectively evaluated the relationship between spine motion and various patient transfer methods to an operating room table for prone positioning. Methods A global instability was surgically created at C5-6 in 4 fresh cadavers with no history of spine pathology. All cadavers were tested both with and without a rigid cervical collar in the intact and unstable state. Three headrest permutations were evaluated Mayfield (SM USA Inc), Prone View (Dupaco, Oceanside, CA), and Foam Pillow (OSI, Union City, CA). A trained group of medical staff performed each of 2 transfer methods: the “manual” and the “Jackson table” transfer. The manual technique entailed performing a standard rotation of the supine patient on a stretcher to the prone position on the operating room table with in-line manual cervical stabilization. The “Jackson” technique involved sliding the supine patient to the Jackson table (OSI, Union City, CA) with manual in-line cervical stabilization, securing them to the table, then initiating the table's lock and turn mechanism and rotating them into a prone position. An electromagnetic tracking device captured angular motion between the C5 and C6 vertebral segments. Repeated measures statistical analysis was performed to evaluate the following conditions: collar use (2 levels), headrest (3 levels), and turning technique (2 levels). Results For all measures, there was significantly more cervical spine motion during manual prone positioning compared with using the Jackson table. The use of a collar provided a slight reduction in motion in all the planes of movement; however, this was only significantly different from the no collar condition in axial rotation. Differences in gross motion between the headrest type were observed in lateral bending (Foam Pillow<Prone View, P=0.045), medial lateral translation (Foam Pillow<Mayfield, P=0.032), and anterior posterior translation (Prone View<Mayfield, P=0.030). Conclusions The data suggest that the manual transfer technique produces 2 to 3 times more cervical spine angular motion than the Jackson table method of transfer. The use of a collar provides significant benefit in limiting spine motion that is only observed in axial rotation. Choice of headrest does have a significant effect on the amount of motion allowed during turning, with the Foam Pillow and Prone View generally providing more effective stabilization compared with the Mayfield.
|
2022-12-17T00:35:16.998Z
|
72,970,362 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/art.38550",
"MAG": "2145342970",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Condylar bony hypertrophy is functionally detrimental for children with JIA. Through gene expression profiling, we have identified dysregulated TGFb‐signaling when fibroblast‐like synoviocytes (FLS) from persistent oligoarticular JIA was compared to controls (heatmap). JIA FLS have a chondrocyte phenotype and may contribute to bony hypertrophy. In the current work, we have expanded the study to determine if FLS from extended oligoarticular (ext) and polyarticular (poly) subtypes also display a chondrocyte phenotype.
|
2022-12-17T01:29:06.312Z
|
76,660,057 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/1078390319832965",
"MAG": "2921025665",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
BACKGROUND: Alzheimer’s disease and related dementias are irreversible, progressive brain disorders that slowly destroy memory, language, problem solving, and cognition. In the United States, dementia is the fifth leading cause of death for people age 65 years and older. Early diagnosis could have important benefits stigma related to dementia remains a significant impediment to diagnosis, treatment, and accessing services. While a growing body of research documents the existence and negative outcomes of stigma, less is known about how dementia-related stigma produces ill effects. AIMS: The purpose of this study was to use qualitative methods to explore how stigma manifests within families from the perspective of family caregivers of people with dementia. METHOD: Using a grounded theory approach, we interviewed 13 family caregivers of people with dementia. RESULTS: Shame emerged as the central theme experienced by family caregivers of people with dementia. Attempting to manage shame, produced three categories of responses: (1) silencing and not calling attention to the symptoms, (2) concealing the diagnosis, and (3) shunning and avoiding contact. CONCLUSIONS: Shame may be an underlying mechanism by which stigma is enacted and perpetuated, resulting in caregivers’ isolation and delay in access to diagnostic and supportive services. Efforts to dispel the misconception that dementia is a shameful disease may be one way to diminish stigma.
|
2022-12-23T21:54:04.684Z
|
237,241,892 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/00034894211039627",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Objectives: The purpose of this study is to compare the number of citations received by open access articles versus subscription access articles in subscription journals in the Otolaryngology literature. Methods: Using the Dimensions research database, we examined articles indexed to PubMed with at least 5 citations published in 2018. Articles were included from Otolaryngology—Head and Neck Surgery, The Laryngoscope, JAMA Otolaryngology—Head and Neck Surgery, Annals of Otology, Rhinology, and Laryngology, and American Journal of Otolaryngology. Multivariate Poisson regression modeling was used to adjust for journal, article type, and topic. Practice guidelines, position statements, or retractions were excluded as potential outliers. Results: 137 open access articles and 337 subscription access articles meeting inclusion criteria were identified, with a median citation number of 8 (IQR 6-11). The most common article type was original investigation (82.5%), and the most common study topic was head and neck (28.9%). Open access articles had a higher median number of citations at 9 (IQR 6-13) when compared to subscription access articles at 7 (IQR 6-10) (P = .032). Open access status was significantly associated with a higher number of citations than subscription access articles when adjusting for journal, article type, and topic (β = .272, CI 0.194-0.500, P < .001). Conclusions: Although comprising a minority of articles examined in this study of subscription journals, open access articles were associated with a higher number of citations than subscription access articles. Open access publishing may facilitate the spread of novel findings in Otolaryngology.
|
2022-12-28T20:24:28.984Z
|
170,095,620 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21847/1728-9343.2012.4(118).16577",
"MAG": "970838420",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
У статті розкрито філософські засади релігієзнавчої проблематики у творчій спадщині мислителів Київської духовної академії, що постає поступовим переходом від фундаментального богослов'я до релігійної філософії, а від релігійної філософії через посилення раціональних методик дослідження до філософії релігії. Проаналізовано питання, які імпліцитно розкривають проблематику і стосуються філософії релігії, а також феноменології та онтології релігії.
|
2022-02-08T17:30:17.248Z
|