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92,616,447 |
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"DOI": "10.3929/ETHZ-A-005807807",
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|
........................................................................................... 1 ZUSAMMENFASSUNG............................................................................ 2 CHAPTER 1: Introduction
|
2022-02-10T18:06:27.208Z
|
64,788,219 |
{
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"DOI": "10.12792/JIIAE.6.47",
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|
Touch screens are useful human interfaces on smartphones. Most touch screens only detect contact position. We propose a proximity and pressure touch-screen method to increase usability. The proposed touch screen consists of plane separated-type and parallel-type electrodes using mutual capacitance measurement. The proposed sensor detects an object and its position using the plane separated-type electrodes within the proximity range. It also detects the pressure and precise center position using the parallel-type electrodes (capacitance pressure sensor) on contact. We believe that the proposed proximity and pressure touch screen will become a functional and useful interface.
|
2022-02-11T13:10:58.547Z
|
182,587,993 |
{
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"ArXiv": null,
"DOI": "10.1109/JEDS.2019.2918146",
"MAG": "2946031827",
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|
A trench-gate field stop insulated gate bipolar transistor (TFS-IGBT) with a novel hybrid <inline-formula> <tex-math notation="LaTeX">${p} ^{+}/{n}$ </tex-math></inline-formula> collector structure is proposed to enhance the trade-off relationship between the on-state voltage drop (<inline-formula> <tex-math notation="LaTeX">${V} _{\mathrm{ on}}$ </tex-math></inline-formula>) and the turn-off energy loss (<inline-formula> <tex-math notation="LaTeX">${E} _{\mathrm{ off}}$ </tex-math></inline-formula>). The proposed hybrid collector structure consists of a <inline-formula> <tex-math notation="LaTeX">${p} ^{+}/{n}$ </tex-math></inline-formula> layer between the <inline-formula> <tex-math notation="LaTeX">${p} ^{+}$ </tex-math></inline-formula> collector and the field stop layer. During turn-on, the <inline-formula> <tex-math notation="LaTeX">${p} ^{+}$ </tex-math></inline-formula> regions in the hybrid <inline-formula> <tex-math notation="LaTeX">${p} ^{+}/{n}$ </tex-math></inline-formula> layer provide high carrier injection efficiency. During turn-off transient, the <inline-formula> <tex-math notation="LaTeX">${n}$ </tex-math></inline-formula>-regions in the hybrid <inline-formula> <tex-math notation="LaTeX">${p} ^{+}/{n}$ </tex-math></inline-formula> collector provide fast carrier extraction paths for holes. 2-D numerical simulations comparing a conventional TFS-IGBT, an injection efficiency controlled IGBT with the proposed hybrid <inline-formula> <tex-math notation="LaTeX">${p} ^{+}/{n}$ </tex-math></inline-formula> collector TFS-IGBT (HC-IGBT) having similar device structures show that for a 1.2 kV rating and with <inline-formula> <tex-math notation="LaTeX">${V} _{\mathrm{ on}}$ </tex-math></inline-formula> at 1.5 V, the HC-IGBT has an advantage in <inline-formula> <tex-math notation="LaTeX">${E} _{\mathrm{ off}}$ </tex-math></inline-formula> reduction by 69% and 22%, respectively. Finally, backside mask alignment is not needed for fabricating the proposed hybrid <inline-formula> <tex-math notation="LaTeX">${p} ^{+}/{n}$ </tex-math></inline-formula> collector structure.
|
2022-06-06T14:50:50.033Z
|
68,498,113 |
{
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"ArXiv": null,
"DOI": "10.2105/ajph.61.7.1277-a",
"MAG": "167471913",
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"license": null,
"status": "GREEN",
"url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1529767"
}
|
The controversy regarding the once widely used mercury-containing preservative thimerosal in childhood vaccines has raised many historical questions that have not been adequately explored. Why was this preservative incorporated in the first place? Was there any real evidence that it caused harm? And how did thimerosal become linked in the public mind to the “autism epidemic”? I examine the origins of the thimerosal controversy and their legacy for the debate that has followed. More specifically, I explore the parallel histories of three factors that converged to create the crisis: vaccine preservatives, mercury poisoning, and autism. An understanding of this history provides important lessons for physicians and policymakers seeking to preserve the public’s trust in the nation’s vaccine system. (Am J Public Health. 2008;98:244‐253. doi:10.2105/AJPH.2007.113159)
|
2022-10-14T00:42:21.907Z
|
9,319,819 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/jssc.201300012",
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|
A rapid analytical method based on rapid resolution LC coupled with MS/MS was first established to quantify seven alkaloids in processed Fuzi decoction. The chromatographic method was optimized to allow simultaneous analysis of all analytes in 5 min and demonstrated good linearity (r > 0.9995), repeatability (RSD < 4.36%), intra- and interday precisions (RSD < 5.07%) with good accuracies (97.76-105.08%) and good recovery (95.0-107.5%) of seven alkaloids, namely higenamine, benzoylhypaconine, benzoylmesaconine, benzoylaconine, aconitine, hypaconitine, and mesaconitine. The LODs for these markers were in the range of 2.30-17.00 pg/mL. Quantitative analysis of the seven alkaloids in Baifupian decoction and Heishunpian decoction showed that the content of the seven marker chemicals varied significantly and concluded that the quality of Fuzi was greatly affected by different processed methods. The developed method could be used as a rapid, sensitive, and reliable approach for assessment of the quality of processed Fuzi and related decoction.
|
2022-12-02T18:39:01.525Z
|
12,104,524 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1109/97.905944",
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"license": null,
"status": "GREEN",
"url": "http://eceserv0.ece.wisc.edu/~sethares/paperspdf/jacobson01.pdf"
}
|
This paper provides a stability analysis of a class of acoustic noise control algorithms by showing that the adapted models have more in common with nonlinear, finite impulse response (FIR) equation error models than with the infinite impulse response (IIR) output error models they superficially resemble. Stability results from the adaptive control literature are applied to show global stability in the noise free case, and to show exponential stability when the input is persistently excited. The latter demonstrates a robustness to mismodeling errors, disturbances such as noises, and allows results to be applied to the tracking of time-varying systems.
|
2022-12-13T12:06:52.305Z
|
42,700,149 |
{
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"DOI": "10.1093/EURHEARTJ/10.SUPPL_C.44",
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"license": null,
"status": null,
"url": null
}
|
Clinical evaluation of oral milrinone in moderate to severe heart failure has demonstrated pronounced beneficial effects. These effects are achieved through increased cardiac index and exercise tolerance, and reduced ventricular filling pressure and systemic vascular resistance. In a double-blind, multicentre study of 230 patients with moderate to severe failure receiving diuretic therapy, treatment with milrinone or digoxin significantly improved exercise capacity. No additional benefit was obtained using combined treatment with the two drugs. A sub-study of 60 patients showed that milrinone produced a significantly higher peak oxygen consumption during treadmill exercise compared with placebo, and approached a significant improvement over digoxin. Milrinone and digoxin favourably influenced symptoms and quality of life measures, but NYHA class was unaltered. Both treatments were well tolerated, alone or combined. A similar study of 155 patients showed comparable results, with no evidence of tolerance development during chronic (3-month) treatment. Survival during the 3-month studies showed a strong correlation with baseline resting left ventricular ejection fraction and was independent of treatment. Neither treatment adversely affected survival. These studies show that milrinone is a well-tolerated and effective oral agent that provides clinical benefits beyond those obtained with diuretics alone in moderate to severe heart failure.
|
2022-12-15T01:01:48.943Z
|
53,978,702 |
{
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"ACL": null,
"ArXiv": "1403.5978",
"DOI": "10.1090/TRAN/6548",
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"url": null
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|
We study the behavior of the bilinear Hilbert transform BHT at the boundary of the known boundedness regionH . A sample of our results is the estimate |〈BHT( f1, f2), f3〉| ≤ C |F1| 3 4 |F2| 3 4 |F3| 1 2 log log ee + |F3| min{|F1|,|F2|} , valid for all tuples of sets F j ⊂ R of finite measure and functions f j such that | f j | ≤ 1F j , j = 1, 2,3, with the additional restriction that f3 be supported on a major subset F ′ 3 of F3 that depends on {F j : j = 1,2, 3}. The use of subindicator functions in this fashion is standard in the given context, see [25]. The double logarithmic term improves over the single logarithmic term obtained in [1]. Whether the double logarithmic term can be removed entirely, as is the case for the quartile operator discussed in [7], remains open. We employ our endpoint results to describe the blow-up rate of weak-type and strong-type estimates for BHT as the tuple ~ α approaches the boundary ofH . We also discuss bounds on Lorentz-Orlicz spaces near L 2 3 , improving on results of [5]. The main technical novelty in our article is an enhanced version of the multi-frequency Calderon-Zygmund decomposition of [26].
|
2022-12-19T04:41:53.879Z
|
151,449,735 |
{
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"DOI": "10.17509/wapfi.v1i1.4894",
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|
Kemampuan berpikir kreatif perlu dikembangkan sejak dini karena diharapkan dapat menjadi bekal dalam menghadapi berbagai permasalahan dalam kehidupan salah satunya melalui Fisika sebagai wahana untuk menumbuhkan kemampuan berpikir. Berdasarkan observasi di SMP 10 Bandung bahwa proses pembelajaran fisika masih didominasi oleh guru. Metode penelitian yang digunakan dalam penelitian ini yaitu quasi experiment sedangkan desain penelitian yang digunakan yaitu One Group Pretest-Posttest Design yang dilakukan sebanyak tiga kali. Pengambilan data dilakukan dengan menggunakan instrumen tes standar kemampuan berpikir kreatif dan prestasi belajar berupa tes dalam bentuk pilihan ganda. Hasil penelitian yang dilakukan menunjukkan adanya peningkatan kemampuan berpikir kreatif pada tiap aspeknya. Untuk Aspek fluency diperoleh peningkatan paling tinggi pada kategori sedang, aspek flexibility diperoleh peningkatan paling tinggi pada kategori sangat kreatif, aspek originality diperoleh peningkatan paling tinggi pada kategori istimewa dan sangat kreatif, dan aspek elaboration diperoleh peningkatan pada kategori sangat kreatif dan sangat baik diatas rata-rata, untuk kategori istimewa pada aspek ini tidak ada peningkatan baik dalam pretest dan posttest. Berkaitan dengan prestasi belajar siswa, pertemuan kedua diperoleh nilai sebesar 0,56 dengan kategori sedang dan pertemuan ketiga diperoleh nilai sebesar 0,69 dengan kategori sedang. Creative thinking skills need to be developed early on because it is expected to be equipped to face the problems of life as through physics as a vehicle to foster thinking skills. Based on the observation in SMP 10 Bandung that learning physics is still dominated by the teacher. The method used in this study is a quasi experiment while the research design used was one group pretest-posttest design is performed three times. Data collection was carried out using standard test instruments the ability to think creatively and achievement in the form of a multiple choice test. The results have shown an increase in the ability to think creatively in every aspect. Aspects of Fluency obtained for the highest increase in the average category, aspects of the flexibility gained the highest increase in the category of very creative, originality aspect gained the highest increase in the category of special and very creative, and gained increasing elaboration aspects of the category of very creative and very good above averages, for a special category in this aspect there is no increase in both the pretest and posttest. Related to student achievement, the second meeting value of 0.56 obtained with the medium category and the third meeting value of 0.69 obtained with the medium category.
|
2022-05-13T14:06:26.057Z
|
3,481,545 |
{
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"ArXiv": null,
"DOI": "10.1080/15412555.2018.1424815",
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"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc6046517?pdf=render"
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|
ABSTRACT Clinical trials of pharmacotherapy in chronic obstructive pulmonary disease (COPD) often include older persons with moderate-to-severe airflow-obstruction, as defined by the Global Initiative for chronic Obstructive Lung Disease (GOLD). In this context, spirometric airflow-obstruction establishes COPD. Because GOLD misidentifies COPD and its severity in older persons, we set out to apply more age-appropriate spirometric criteria from the Global Lung function Initiative (GLI) in a prior clinical trial of COPD pharmacotherapy, specifically the Towards a Revolution in COPD Health (TORCH) trial — N = 6,112, mean age 65 years. In the TORCH trial, which enrolled GOLD-defined moderate COPD (26.2%, n = 1,200) and GOLD-defined severe COPD (73.8%, n = 4,511), the GLI reclassification yielded a higher frequency of severe COPD (89.6%, n = 5,474), the inclusion of restrictive-pattern (6.9%, n = 420) and, in turn, a very low frequency of moderate COPD (3.5%, n = 212). These GLI reclassification results suggest that GOLD-based enrollment criteria for the TORCH trial may have assembled a cohort that was: 1) less likely to respond to COPD pharmacotherapy, given the greater representation of severe COPD, very minor representation of moderate COPD, and inclusion of a non-obstructive spirometric impairment (restrictive-pattern); and 2) more likely to have medication-related adverse events, given the inappropriate use of COPD pharmacotherapy in misidentified COPD (restrictive-pattern). We therefore propose that future clinical trials of COPD pharmacotherapy should consider GLI criteria for defining COPD, including a greater representation of GLI-defined moderate COPD.
|
2022-09-07T15:21:00.355Z
|
136,929,537 |
{
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"DOI": "10.1179/SUR.1991.7.1.29",
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"url": null
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|
AbstractNitrocarburising is outstanding for the profusion of proprietary names and claims it has attracted during its 40 year existence. It can be characterised as a low distortion treatment for ferrous materials where surface enrichment, predominantly by nitrogen, forms a hard surface layer of e iron nitride, beneath which there is a nitrogen diffusion zone. The surface layer imparts wear and corrosion resistance and the diffusion zone increases the yield and fatigue strength, particularly in thin sections. Process developments have significantly enhanced the corrosion resistance and aesthetic appearance of treated components to make nitrocarburising competitive with electroplated finishes. Major commercialisation took place duringthe 1980s, and examples are given of a wide range of successful applications from wheel bearings to bumper armatures, which use combinations of the properties obtainable from the process to provide cost and weight savings. Advances in equipment and process materials offer a tre...
|
2022-09-09T01:36:17.762Z
|
108,245,791 |
{
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"ArXiv": null,
"DOI": "10.21236/ada370694",
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}
|
Abstract : The author traces the evolution of Network Centric Warfare, showing its American roots. He shows that NCW is not a remote concept on the horizon, it is nascent in today's maritime operations and inevitably will be the way in which the U.S. Navy will fight future wars. Then he reveals a gaping mismatch between the emerging operational doctrine and the strategy it will be tasked to support. Since it is largely an American conception for warfare, the United States thus bears the burden to pursue interoperability with regional coalition partners if it is to fight "together when we can, alone if we must." Finally, the author presents options for addressing this strategic/operational mismatch and proposes a way ahead."
|
2022-09-12T10:44:28.102Z
|
220,406,853 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1177/002070206602100112",
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|
revolutionary rhetoric. But it is impossible for present day America, worshipping at the shrines of the religion of self-enrichment, to really conduct a policy of social revolution abroad (p. 238). Yet in other passages of his essay, Sinai complains peevishly because Asians do not seem capable of enriching themselves. Hence if a conservative America could propagate its peculiar ethos-nud-Victorian or notsurely a real revolution would ensue. Perhaps the oddest thing about this book is its unexpected conclusion, for the closing chapter urges the separate nations of the Atlantic community to unite post haste in order to defend themselves against an unfriendly and menacing outside world, which, presumably, is simply to be left to stew in its own unsavoury juice. Mr. Sinai, in short, appears to be a Little Englander imperfectly brought up to date.
|
2022-09-13T22:34:29.460Z
|
159,314,488 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1017/CBO9780511809286.007",
"MAG": "1430284574",
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"url": null
}
|
The central question in political philosophy is whether political states have the right to coerce their constituents and whether citizens have a moral duty to obey the commands of their state. Christopher Heath Wellman and A. John Simmons defend opposing answers to this question. Wellman bases his argument on samaritan obligations to perform easy rescues, arguing that each of us has a moral duty to obey the law as his or her fair share of the communal samaritan chore of rescuing our compatriots from the perils of the state of nature. Simmons counters that this and all other attempts to explain our duty to obey the law fail. Concentrating especially on refuting Natural Duty accounts of the duty to obey, he ultimately defends the view that there is no strong moral presumption in favor of obedience to or compliance with any existing state.
|
2022-09-14T12:36:12.721Z
|
206,438,105 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/acsami.6b14754",
"MAG": "2570212858",
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"license": null,
"status": null,
"url": null
}
|
We synthesized a novel nonprecious metal electrocatalyst by pyrolysis of a colloid mixture consisting of a tungsten source and phenolic resin, with the simultaneous addition of ferric salt. The rationally designed electrocatalyst has a unique structure, with nanosized WC and Fe3W3C uniformly dispersed in a three-dimensional porous carbon framework. WC, which was thought difficult to produce, is successfully prepared at a relatively low temperature of about 750 °C at an inert atmosphere. XRD studies demonstrate the self-assisted effect of Fe, which accelerates the formation of WC, getting around the pathway of direct carbonaceous reduction of tungsten by carbon. The porous iron-tungsten carbide (Fe-W-C) nanocomposite as electrocatalyst shows excellent ORR activity with the onset and half-wave potentials of 0.864 and 0.727 V (vs RHE), respectively, which are close to those of Pt/C (0.976 and 0.820 V vs RHE). Electrochemical measurements show that Fe-W-C follows almost the effective four-electron-transfer pathway and would not be disturbed by methanol. The presence of a protective graphite shell outside the active carbide cores substantially improves the durability of the electrocatalyst. Both the removal of Fe species and the absence of W species would severely degrade the activity, while halide ions Cl- and sulfur-containing species SCN- can significantly suppress the ORR activity by the blocking of Fe species. These facts indicate that the ORR active species of Fe-W-C should be relevant to both W and Fe species.
|
2022-12-07T22:34:35.228Z
|
103,284,614 |
{
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"DOI": "10.1088/1361-6595/aa76f7",
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"status": null,
"url": null
}
|
Two-photon absorption laser-induced fluorescence (TALIF) was utilized for measuring the concentration of atomic hydrogen in a volume dielectric barrier discharge (DBD) ignited in mixtures of Ar, H2 and O2 at atmospheric pressure. The method was calibrated by TALIF of krypton diluted in argon at atmospheric pressure, proving that three-body collisions had a negligible effect on quenching of excited krypton atoms. The diagnostic study was complemented with a 3D numerical model of the gas flow and a zero-dimensional model of the chemistry in order to better understand the reaction kinetics and identify the key pathways leading to the production and destruction of atomic hydrogen. It was determined that the density of atomic hydrogen in Ar–H2 mixtures was in the order of 1021 m−3 and decreased when oxygen was added into the gas mixture. Spatially resolved measurements and simulations revealed a sharply bordered region with low atomic hydrogen concentration when oxygen was added to the gas mixture. At substoichiometric oxygen/hydrogen ratios, this H-poor region is confined to an area close to the gas inlet and it is shown that the size of this region is not only influenced by the chemistry but also by the gas flow patterns. Experimentally, it was observed that a decrease in H2 concentration in the feeding Ar–H2 mixture led to an increase in H production in the DBD.
|
2022-12-12T05:11:14.040Z
|
231,803,559 |
{
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"DOI": "10.1097/HPC.0000000000000254",
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|
Background: Data evaluating the impact of the history, ECG, age, risk factors, and troponin (HEART) Pathway on observation unit (OU) use is limited. The objective of this study is to determine how HEART Pathway implementation affects OU use. Methods: An analysis of OU registry data from October 2012 to October 2016, 2 years before and after HEART Pathway implementation at an academic medical center, was conducted. Adult patients placed in the OU for chest pain were included. The proportion of patients placed in the OU chest pain protocol per total OU volume and hospitalization and myocardial infarction (MI) rates were determined. Proportions before versus after implementation were compared using χ2 tests and age was compared using a Mann-Whitney U test. Results: During the study period, 1688 patients with chest pain before HEART Pathway implementation and 1692 after were included. The proportion of chest pain patients in the OU per total OU volume decreased following implementation from (57% [1688/2968] to 43.6% [1692/3882]; P < 0.001). Before HEART Pathway implementation, the hospitalization rate was 10.4% (175/1688) versus 12.4% (210/1692) after (P = 0.07). More patients were diagnosed with MI following implementation (0.8% [14/1665] vs. 2.0% [33/1686]; P = 0. 008). Median age was older postimplementation (52 years [IQR: 45–59 years] vs. 54 years [IQR: 48–64 years]; P < 0. 001). Conclusions: HEART Pathway implementation resulted in management of higher risk patients in the OU. Following implementation, OU chest pain patients were older and were more likely to be hospitalized or diagnosed with MI.
|
2022-12-13T08:33:45.041Z
|
167,414,460 |
{
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"DOI": "10.2139/SSRN.2207259",
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"license": null,
"status": null,
"url": null
}
|
Sovereign wealth funds (SWFs) have been likened to “regulatory chameleons." Their existence flies in the face of the truism that there is no room for state participation in private markets. This paper examines the validity of Member State concerns that have arisen in relation to SWF investment in equities; and has forwarded the argument that the existing EU Treaty framework offers sovereign investors the most legal certainty. In particular, it is posited that SWF investments are particularly amenable to the application of Article 63 TFEU.There are a number of strong policy reasons to require greater disclosure from SWFs, but transparency should not be regarded as a magic panacea for the problems that arise in situations where States behave like private investors. It is submitted that the biggest impediment to an effective regulatory framework is the insurmountable task of devising a conceptual framework which accurately reflects the investment patterns and behavioural trends of sovereign wealth funds.
|
2022-02-08T18:59:43.784Z
|
243,837,348 |
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"DOI": "10.32520/jupel.v3i3.1738",
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"license": "CCBYNCSA",
"status": "GOLD",
"url": "https://ejournal.unisi.ac.id/index.php/jupel/article/download/1738/1040"
}
|
Posyandu Srikandi II merupakan suatu unit layanan kesehatan yang bertugas untuk melakukan pelayanan kesehatan ibu dan anak (KIA) di wilayah RT 05 d RW 09 Kelurahan Kempas Jaya, Kecamatan Kempas. Saat ini, proses manajemen data di Posyandu Srikandi II masih dilakukan secara manual dengan cara mencatatkan data kedalam buku format register. Cara tersebut dinilai tidak efisien karena menyebabkan kesulitan dalam proses manajemen data Posyandu Srikandi II. Untuk mengatasi permasalahan tersebut, maka penulis bermaksud mengembangkan suatu sistem informasi posyandu berbasis web. Pengumpulan data dilakukan dengan cara observasi dan wawancara. Metode pengembangan sistem yang digunakan adalah Unified Modelling Language (UML). Alat yang digunakan dalam analisis dan perancangan sistem adalah Use Case Diagram, Activity Diagram, Squance Diagram, dan Class Diagram. Dari hasil pengujian dan wawancara evaluasi yang dilakukan dengan Ketua Posyandu Srikandi II, disimpulkan bahwa aplikasi eposyandu ini dapat memudahkan proses pengolahan, pencarian, dan pelaporan data kegiatan Posyandu Srikandi II. Pada pengembangan selanjutnya, diharapkan sistem informasi posyandu ini dilengkapi dengan fitur grafik pita KMS untuk memantau perkembangan berat badan anak.
|
2022-02-18T00:46:43.026Z
|
149,632,281 |
{
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"DOI": "10.2307/494011",
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"status": "CLOSED",
"url": null
}
|
A solution to get the problem off, have you found it? Really? What kind of solution do you resolve the problem? From what sources? Well, there are so many questions that we utter every day. No matter how you will get the solution, it will mean better. You can take the reference from some books. And the the young nixon an oral inquiry is one book that we really recommend you to read, to get more solutions in solving this problem.
|
2022-08-29T10:32:56.302Z
|
144,290,449 |
{
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"DOI": "10.3917/RFP.773.0738",
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}
|
Apres avoir mis en evidence et donne son plein developpement aux manifestations du transfert dans la cure, Freud en a elabore la theorie tout au long de sa vie. Celle-ci n’a pu etre recusee au point que, dans leur ensemble, les adversaires de la psychanalyse evitent d’aborder cette question. Dans cet article, l’auteur a voulu rappeler le role meconnu de la « methode des transferts », utilisee par Charcot et Babinski dans le traitement des hysteriques, dans la genese de la decouverte de la nevrose de transfert.
|
2022-09-09T07:29:12.998Z
|
147,627,761 |
{
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"DOI": "10.2307/3322114",
"MAG": "2275324634",
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},
"license": null,
"status": null,
"url": null
}
|
Vincent Caradec : Das Problem des « richtigen Eheabstandes » beim Eintritt in den Ruhestand. Dieses Aufsatz untersucht die chelichen Beziehungen nach Eintritt in den Ruhestand und behandelt sie anhand des Problems des « richtigen Abstandes ». Die Ehepartner miissen zu diesem Zeitpunkt eine beide Seiten zufriedenstellende Losung finden. Eine Dimension dieses Eingliederungsabstandes erscheint als diskriminierend - die Ehebeziehung zur Aussenwelt - und erlaubt die Untersuchung zwischen fusionellen und unabhangigen Haltungen. Mit Hilfe der Kreuzung der Ehebeziehungen zur Aussenwelt mit einer zweiten Variabel - die individuelle Beziehung zur Aussenwelt (auf der zentripetale und zentrifugale Haltungen gegenuberstehen) - kann man eine gewisse Anzahl von ehelichen Schwierigkeiten aufzeichnen, die beim Eintritt in den Ruhestand auftreten. Somit kann man gleichzeitig prtifen, wie der eheliche Abstand erarbeitet wird und sich entwickelt.
|
2022-09-14T16:42:31.178Z
|
230,581,842 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4236/ojmsi.2021.91002",
"MAG": "3112534483",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "http://www.scirp.org/journal/PaperDownload.aspx?paperID=105854"
}
|
Ohmic
Heating (OH) is one of the emerging thermal technologies used in food
processing which can produce rapid and uniform heating with close to 100%
energy transfer efficiency. Although mathematical modelling for OH processes has been studied by many researchers in
recent years, systematic simulations of OH have not been developed for
model-based control of the processes. In this paper, mathematical model for a Colinear Ohmic Heater is presented,
analyzed, and studied based on the selected configuration. A numerical solution
for the mathematical equations has been defined and proposed. MATLAB/Simulink
model is hence developed and validated against the available data. Simulation
results have shown that MATLAB/Simulink
model can produce robust outputs at low computational costs with an accuracy of
up to 99.6% in comparison to the analytical solution. This model can be used in
further studies for analysis of the OH processes and development of advanced
controllers.
|
2022-10-13T15:20:27.368Z
|
22,908,086 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1039/b904021h",
"MAG": "2952023488",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
An efficient, economic and environmentally friendly enantioselective oxidation of racemic benzoins (alpha-hydroxy ketones) catalyzed by a chiral iron complex has been developed using molecular oxygen as a terminal oxidant with good selectivity and excellent enantiomeric excess.
|
2022-12-14T04:04:03.616Z
|
40,306,609 |
{
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"ArXiv": null,
"DOI": "10.1080/10473289.2005.10464600",
"MAG": "2089474186",
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},
"license": null,
"status": "BRONZE",
"url": "https://www.tandfonline.com/doi/pdf/10.1080/10473289.2005.10464600?needAccess=true"
}
|
Abstract The San Joaquin Valley (SJV) in California has one of the most severe particulate air quality problems in the United States during the winter season. In the current study, measurements of particulate matter (PM) smaller than 10 [H9262]m in aerodynamic diameter (PM10), fine particles (PM1.8), and ultrafine particles (PM0.1) made during the period December 16, 2000–February 3, 2001, at six locations near or within the SJV are discussed: Bodega Bay, Davis, Sacramento, Modesto, Bakersfield, and Sequoia National Park. Airborne PM1.8 concentrations at the most heavily polluted site (Bakersfield) increased from 20 to 172 [H9262]g/m3 during the period December 16, 2000–January 7, 2001. The majority of the fine particle mass was ammonium nitrate driven by an excess of gas-phase ammonia. Peak PM0.1 concentrations (8–12 hr average) were [H11011]2.4 [H9262]g/m3 measured at night in Sacramento and Bakers-field. Ultrafine particle concentrations were distinctly diurnal, with daytime concentrations [H11011]50% lower than nighttime concentrations. PM0.1 concentrations did not accumulate during the multiweek stagnation period; rather, PM0.1 mass decreased at Bakersfield as PM1.8 mass was increasing. The majority of the ultrafine particle mass was associated with carbonaceous material. The high concentrations of ultrafine particles in the SJV pose a potential serious public health threat that should be addressed.
|
2022-12-20T01:59:58.912Z
|
254,663,639 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1155/2022/8245306",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://downloads.hindawi.com/journals/wcmc/2022/8245306.pdf"
}
|
Recent studies have demonstrated the advantage of applying mobile sink to prevent the energy-hole problem and prolong network lifetime in wireless sensor network. However, most researches treat the touring length constraint simply as the termination indicator of rendezvous point selection, which leads to a suboptimal solution. In this paper, we notice that the optimal set of rendezvous points is unknown but deterministic and propose to elect the set of rendezvous points directly with the multiwinner voting-based method instead of step-by-step selection. A weighted heuristic voter generation method is introduced to choose the representative voters, and a scoring rule is also well designed to obtain a satisfying solution. We also employ an iterative schema for the voting score update to refine the solution. We have conducted extensive experiments, and the results show that the proposed method can effectively prolong the network lifetime and achieve the competitive performance with other SOTA methods. Compared to the methods based on step-by-step selection, the proposed method increases the network lifetime by 23.2% and 10.5% on average under the balanced-distribution and unbalanced-distribution scenarios, respectively.
|
2022-12-17T10:06:10.285Z
|
151,929,551 |
{
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"ArXiv": null,
"DOI": "10.1353/NHR.2016.0056",
"MAG": "2584762449",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Back then, I used words as coded transcripts of my days: private riddles, silence bound in bantam boxes, sounds paged in poems. And now my words are weighed by water, a discourse on the seas—phrased lines at the bitter end of cables to the quays, quotes verbatim et literatim. A numbered few sealed in suits and yellow boots crew lifeboats to the scene, to snare that rabid creature fear, cast it down, well aware it’ll snare them too given half a chance. I’ve been told hope floats, and now I’m certain dread does too, holding fast to fear. But it’s people that concern us, and when we leave them safely on the shore we must return a transcript of their story, engage the sea’s fickle nature to describe it and disarm it, persuade others of the folly at its core, then not in ways preachers use, but as illustrator, as teacher. Yet, some scenes are seen for which we have no words, dislimn or unknown, silence bound in bantam boxes, sounds paged in poems.
|
2022-06-30T23:54:17.511Z
|
58,668,219 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.3390/s19020325",
"MAG": "2908840554",
"PubMedCentral": "6359746"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/1424-8220/19/2/325/pdf?version=1547606208"
}
|
Affinity biosensors of interdigitated electrodes have been widely used in cell detection. This research presents a mass-producible and disposable three-dimensional (3D) structure capacitive sensor based on the integrated circuit package lead frames for cell concentration detection. The fully symmetric 3D interdigital electrode structure makes the sensor more homogeneous and sensitive. (3-Aminopropyl) triethoxysilane (APTES) and glutaraldehyde are immobilized onto gold-plated electrodes. By overlaying the microfluidic channels on top, the volume of the solution is kept constant to obtain repeatable measured capacitance values. Moreover, using the upgraded reading and writing functions and circular measurement of the E4980A Data Transfer Program, an automatic multigroup test system is developed. It is shown that the cell concentration and capacitance are inversely correlated, and the cell concentration range of 103–106 CFU∙mL−1 is achieved. In addition, the rate of capacitance change matches that of state-of-the-art biosensors reported. A program is developed to find the optimal voltage and frequency for linear fitting between the capacitance change and cell concentration. Future work will employ machine learning-based data analysis to drug resistance sensitivity test of cell lines and cell survival status.
|
2022-12-02T11:29:10.606Z
|
149,632,854 |
{
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"ArXiv": null,
"DOI": "10.5117/SOC2017.1.DAAL",
"MAG": "2807964821",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In 2017, the WRR (The Netherlands Scientific Council for Government Policy) published the report De val van de middenklasse? Het stabiele en kwetsbare midden (The fall of the middle class? The stable and vulnerable middle), edited by Godfried Engbersen, Erik Snel en Monique Kremer. The report investigates changes in the social position of ‘the middle classes’ in the Netherlands between 1980 and 2010. The report gives a broad and dynamic portrait of ‘the middle classes’, using different perspectives.
In this essay, the author reflects on some of its key findings. A remaining issue is: who belongs to the middle classes? Seen from the perspective of income, occupation and education, the composition of the middle classes appears to change, while people participating in focus groups all define themselves as belonging to the middle classes. One would expect that the authors give much attention to the difficulties of defining the ‘middle classes’, but that is not the case. What does that say about the social stratification in the Netherlands in the 21st century?
Furthermore, the report demonstrates that Dutch society has become a middle-class society, which in the 21st century has to deal with growing insecurity on the labor market and an increasingly restrictive welfare state. In her essay, the author asks why a report on the position of the middle class does not consider the international context, given that social changes and the position of the middle class are the result of increasing interdependencies on a global scale.
|
2022-12-11T02:08:00.914Z
|
4,649,358 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2144/000112049",
"MAG": "2117051710",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://doi.org/10.2144/000112049"
}
|
Counter-selectable markers can be used in two-hybrid systems to search libraries for a protein or compound that interferes with a macromolecular interaction or to identify macromolecules from a population that cannot mediate a particular interaction. In this report, we describe the adaptation of the yeast URA3/5-FOA counter-selection system for use in bacterial interaction trap experiments. Two different URA3 reporter systems were developed that allow robust counter-selection: (i) a single copy F' episome reporter and (ii) a co-cistronic HIS3-URA3 reporter vector. The HIS3-URA3 reporter can be used for either positive or negative selections in appropriate bacterial strains. These reagents extend the utility of the bacterial two-hybrid system as an alternative to its yeast-based counterpart.
|
2022-12-13T04:05:57.952Z
|
35,203,549 |
{
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"ArXiv": null,
"DOI": "10.1093/heapro/dax092",
"MAG": "2772650457",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://lirias.kuleuven.be/bitstream/123456789/599416/4/AcceptedRevisedMain%20manuscript_Boen.docx"
}
|
Based on the principles of the Social Identity Approach (SIA), the present experiment aimed to examine the impact of communicating descriptive age norms on older adults' autonomous motivation to exercise. Under the cover of a marketing study, older adults (n = 120; age = 65-70 years) participated in a newly created exercise activity, 'Pattern Stepping'. This activity was framed as an activity that was descriptively normative either for older adults, for younger adults, for both groups, or for none. Repeated measures ANOVAs revealed that participants felt greater satisfaction of their basic psychological needs and were more autonomously motivated to exercise if Pattern Stepping was framed as an activity popular among the young, rather than among older adults. These findings suggest that framing an exercise as descriptively normative for the elderly can thwart older adults' autonomous motivation if they do not identify as an older adult.
|
2022-12-13T13:45:15.183Z
|
155,722,471 |
{
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"ArXiv": null,
"DOI": "10.1002/adfm.201901009",
"MAG": "2942956266",
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},
"license": null,
"status": null,
"url": null
}
|
Marine sponges are used as biomonitors of heavy metals contamination in coastal environment as they process large amounts of water and have a high capacity for accumulating heavy metals. Here, inspired by the unique physical and physiological features of marine sponges, a surface engineered synthetic sponge for the highly efficient harvesting of uranium from natural seawater is developed. An ultrathin poly(imide dioxime) (PIDO)/alginate (Alg) interpenetrating polymer network hydrogel layer is uniformly wrapped around the skeleton of a melamine sponge (MS) substrate through a simple dipping–drying–crosslinking process, providing the hybrid MS@PIDO/Alg sponge with excellent uranium adsorption performance and sufficient mechanical strength to withstand the harsh conditions of practical applications. The maximum adsorption capacity reaches 910.98 mg‐U g‐gel‐1 for the PIDO/Alg hydrogel layer and 291.51 mg‐U g‐sponge‐1 for the whole hybrid MS@PIDO/Alg sponge in uranium‐spiked natural seawater. The adsorption capacity measured after 56 d of exposure in 5 tons of natural seawater is evaluated to be 5.84 mg‐U g‐gel‐1 (1.87 mg‐U g‐sponge‐1). This novel approach shows great promise for the mass production of high‐performance sponge adsorbent for uranium recovery from natural seawater and nuclear waste.
|
2022-12-20T10:16:13.988Z
|
3,127,424 |
{
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"ArXiv": null,
"DOI": "10.1094/MPMI-20-10-1222",
"MAG": "2053439012",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The phytopathogenic bacterium Xanthomonas axonopodis pv. citri is responsible for the canker disease affecting citrus plants throughout the world. Here, we have evaluated the role of bacterial attachment and biofilm formation in leaf colonization during canker development on lemon leaves. Crystal violet staining and confocal laser scanning microscopy analysis of X. axonopodis pv. citri strains expressing the green fluorescent protein were used to evaluate attachment and biofilm formation on abiotic and biotic (leaf) surfaces. Wild-type X. axonopodis pv. citri attached to and formed a complex, structured biofilm on glass in minimal medium containing glucose. Similar attachment and structured biofilm formation also were seen on lemon leaves. An X. axonopodis pv. citri gumB mutant strain, defective in production of the extracellular polysaccharide xanthan, did not form a structured biofilm on either abiotic or biotic surfaces. In addition, the X. axonopodis pv. citri gumB showed reduced growth and survival on leaf surfaces and reduced disease symptoms. These findings suggest an important role for formation of biofilms in the epiphytic survival of X. axonopodis pv. citri prior to development of canker disease.
|
2022-12-29T17:08:37.170Z
|
205,525,629 |
{
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"ArXiv": null,
"DOI": "10.1002/bmc.3799",
"MAG": "2479193804",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The X-ray diagnostic agent sodium diatrizoate (DTA) was studied for chemical degradation. The 3,5-diamino derivative was found to be the alkaline and acidic degradation product. The 3,5-diamino degradate is also the synthetic precursor of DTA and it is proved to have cytotoxic and mutagenic effects. A sensitive, selective and precise high-performance liquid chromatographic stability-indicating method for the determination of DTA in the presence of its acidic degradation product and in pharmaceutical formulation was developed and validated. Owing to the high toxicity of the degradation product, the kinetics of the acidic degradation process was monitored by the developed RP-HPLC method. The reaction was found to follow pseudo-first order kinetics. The kinetic parameters such as rate constant (K) and half-life (t½ ) were calculated under different temperatures and acid concentrations; activation energy was estimated from the Arrhenius plot. The developed RP-HPLC method depends on isocratic elution of a mobile phase composed of methanol-water (25:75 v/v; pH adjusted with phosphoric acid), and UV detection at 238 nm. The method showed good linearity over a concentration range of 2-100 μg/mL with mean percentage recovery of 100.04 ± 1.07. The selectivity of the proposed method was tested using laboratory-prepared mixtures. The proposed method has been successfully applied to the analysis of DTA in pharmaceutical dosage forms without interference from other dosage form additives and the results were statistically compared with the official USP method. Validation of the proposed method was performed according to International Conference on Harmonization guidelines.
|
2022-01-27T14:47:22.708Z
|
146,761,760 |
{
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"ArXiv": null,
"DOI": "10.1080/02691729808578867",
"MAG": "2207829318",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Se referant a la reflexion de G. Delanty sur l'idee de l'universite, l'A. repond a plusieurs questions concernant la necessite d'un changement dans le professorat: 1) si la connaissance devient bâtarde, la theorie sociale est-elle le dernier bastion de la purete?; 2) qui sont-ceux qui parlent de fragmentation?; 3) la specialisation n'est pas la meme chose que la fragmentation; 4)la fin de la connaissance est seulement le debut du travail. Soulignant l'aspect premature de l'annonce de la mort du professeur en Grande-Bretagne, l'A. contribue a la reflexion sur l'avenir de l'universite en soulevant le probleme des conditions de travail et des contrats des professeurs dans le milieu academique anglais
|
2022-02-09T05:45:58.890Z
|
145,695,769 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1080/01634372.2013.855605",
"MAG": "2126425575",
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},
"license": null,
"status": null,
"url": null
}
|
Baby-boomers began to turn into 65 in 2011; thus, the book entitled Social Insurance and Social Justice: Social Security, Medicare and the Campaign Against Entitlements was a timely publication. This book is especially meaningful in that it is dedicated to the memory of Robert M. Ball, who served as commissioner of the Social Security Administration under Presidents Kennedy, Johnson, and Nixon, and passed away in 2008. Featuring the voices of some of the most esteemed scholars in the field, the book is a stirring call for social solidarity. The book is an outgrowth of efforts by an intergenerational group of students and scholars—from critical gerontology and public social science—who pursue development and promotion of an organized alternative to the neoliberal debate on privatization. The authors founded two groups: Concerned Scientists in Aging and Students for Social Security. They aim to advance the role of universities as partners in the conversation about social insurance as a human right and to promote evidenced-based knowledge concerning the role of social insurance as a means of economic security. The book is impressive in both scope and depth, covering content from the founding concepts and history of social insurance to current policy debates over social insurance programs. Specifically, this book consists of five parts: (1) social insurance: history, politics, and prospects; (2) discussion of what is at stake for various groups such as women, people of color, and the working and nonworking poor; (3) the ongoing debates over the future of social insurance; (4) critical perspectives on social insurance reform; and (5) empowering and educating students and the public about the importance of social insurance. The first two parts of the book present the history of social insurance in the United States and its fundamental values and principles. Social Security and Medicare are grounded in the values of shared responsibility for all human beings, mutual support, and the belief in a protective government
|
2022-02-09T06:21:58.006Z
|
188,717,929 |
{
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"ArXiv": null,
"DOI": "10.30906/0023-1134-2018-52-12-45-49",
"MAG": "2911384608",
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},
"license": null,
"status": null,
"url": null
}
|
Предложен селективный энтеросорбент на основе фиброина натурального шелка, превышающий по своим детоксикационным свойствам традиционные углеродные сорбенты (СКН-2К, СКН-4М). Для усиления саногенного действия полученного энтеросорбента показана возможность использования его в качестве матрицы для лекарственных средств и создания новой полимерной лекарственной формы. Получены и исследованы «комплексы включения» энтеросорбента с хлоргидратом бензимидазолил-2-метилкарбамата (I). Показано, что в процессе взаимодействия энтеросорбента с I образуются водородные связи.
|
2022-02-08T10:09:10.141Z
|
98,493,121 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1116/1.577176",
"MAG": "2088558977",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The electron trapping phenomenon in a‐SiN:H films deposited by radio frequency (rf) glow discharge has been studied as a function of rf power and gas feed ratio. The chemical composition of the films was determined with Fourier transform infrared spectroscopy. The nitrogen content of the films increased with rf power level if the feed ratio of silane to ammonia was sufficient, 1:10. A gas ratio of 1:5 lacked sufficient ammonia fraction to yield nitrogen rich films despite an increase in rf power level. The electrical resistivity increased and in general electron trapping decreased with increasing nitrogen content in the a‐SiN:H films. There is weak experimental evidence that an electron trapping minimum is obtained at a film composition similar to stoichiometric silicon nitride. The measured coordination number of 2.4 for films at this stoichiometric ratio corresponded to the optimum coordination number for a random covalent network. This conceivably should yield the lowest trap density material. At this ...
|
2022-02-10T12:32:03.082Z
|
56,597,363 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1109/EI2.2018.8582358",
"MAG": "2906001593",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
With the increasing mutual interaction between smart grid and users, intelligent acquisition terminals and mobile operation terminals are widely used and accessed. The types of data transmitted in the network are more complex, and the requirements for information security protection are higher. Currently, the general security protocols for power systems do not meet the new requirements. This paper studies ISO/IEC 9798 series of standards, combines key agreement, entity authentication and hybrid algorithm technology, designs a secure channel protocol for high-security data transmission, and analyzes its complexity and time performance. Finally, it is completed based on security chip. Data transmission test shows that it has the characteristics of high security and flexible protocol, and can effectively meet the security and real-time requirements of data communication.
|
2022-02-11T19:11:29.933Z
|
109,137,250 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1108/02656710810873916",
"MAG": "1973895934",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Purpose – The purpose of this paper is to model an inspection maintenance strategy that is superior to existing strategies and which incorporates the inspection factor.Design/methodology/approach – An appropriate inspection maintenance strategy can help prevent breakdown failure and reduce breakdown and repair costs. However, every inspection also incurs costs. The optimal model for an inspection maintenance strategy would be such that the inspection frequency closely follows the hazard rate of the equipment over its lifetime.Findings – A model with a three‐layered structure needs to be developed. Over time, equipment can be expected to demonstrate a hazard rate that is decreasing, constant or increasing with time. In the first stage a model for inspection frequency is developed that is time‐dependent and can address this requirement. Second, the hazard rate has a dynamic relationship with the inspection frequency, i.e. as the inspection frequency increases, the hazard rate is known to decrease. In the se...
|
2022-12-05T18:03:30.986Z
|
252,757,741 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/17460263.2022.2126516",
"MAG": null,
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},
"license": null,
"status": null,
"url": null
}
|
As the Chair of the British Society of Sports History during its 40th anniversary year, I was delighted to be asked to write the Introduction to this special issue, celebrating four decades of our existence as the BSSH. I want to emphasise at the outset, though, that the hard work which has gone into conceiving, commissioning, collating and editing the articles which appear in the following pages is that of the special issue editors, Conor Heffernan and Katie Taylor. It was in the first year of my term as Chair, November 2019 back in the era before ‘social distancing’ became a regular part of all our vocabularies that I had the good fortune of being sat next to Professor Richard Holt at a dinner in Leicester. Towards the end of the evening, Dick leaned back in his chair, looked over at me, and remarked that he felt sure the 40th anniversary of the Society would soon be approaching, and what would we be doing to celebrate? Truth be told, I had given it very little thought; had it not been for that fortuitous conversation, this special issue (and the surrounding 40th anniversary activities) might well never have come to bear. Not for the first time, the field of British sports history finds itself in enormous debt to Professor Holt. When I went away to read up on the history of the BSSH, I found that in common with many sports there is some dispute as to the exact founding ‘date’ of the Society. J.A. Mangan has it as March 1983; but Carol Osborne and Dil Porter’s recent hunt in the BSSH archives has uncovered an ‘inaugural meeting’ of BSSH dated 21March 1982, as part of a conference at the University of Liverpool organised by Richard Cox. After discussion, we as a Board of Trustees were nonetheless content to settle on 2022 (40 years since the first BSSH conference took place) as the year in which to focus our anniversary celebrations.
|
2022-12-15T03:50:40.256Z
|
221,842,062 |
{
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"DOI": "10.1111/jcpp.13324",
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"status": "GREEN",
"url": "https://ora.ox.ac.uk/objects/uuid:2700d748-bc88-4f41-9a80-6537f2813df2/download_file?safe_filename=Snowling_and_Hulme_2020_reading_disorders_revisited_the_critical_importance_of.pdf&file_format=pdf&type_of_work=Journal+article"
}
|
This paper discusses research on reading disorders during the period since their classification within the overarching category of neurodevelopmental disorders (Journal of Child Psychology and Psychiatry, 53, 2012, 593). Following a review of the predictors of learning to read across languages, and the role of language skills as critical foundations for literacy, profiles of reading disorders are discussed and putative causal risk factors at the cognitive, biological, and environmental levels of explanation considered. Reading disorders are highly heritable and highly comorbid with disorders of language, attention, and other learning disorders, notably mathematics disorders. The home literacy environment, reflecting gene-environment correlation, is one of several factors that promote reading development and highlight an important target for intervention. The multiple deficit view of dyslexia (Cognition, 101, 2006, 385) suggests that risks accumulate to a diagnostic threshold although categorical diagnoses tend to be unstable. Implications for assessment and intervention are discussed.
|
2022-12-25T17:58:00.145Z
|
204,821,457 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/EXPAT.2019.8876547",
"MAG": "2981388827",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
An adaptive serious game on Statistics is being under development in the framework of higher education. The main objective of this serious game is to promote and explain the applicability of statistics concepts in day-to-day life and in the decision-making process. The present work stresses the project development and mechanisms including the storyboard and game scenarios. The storyboard is based on a mystery where the clues and answers are defined in terms of statistics knowledge (probabilities, confidence intervals, hypotheses tests). The game scenarios were developed using open source tools and using as reference scenario the university campus. By doing this, the student/player are integrated in a "familiar" environment. It is expected to increase the students’ proficiency on Statistics.
|
2022-01-27T05:30:42.071Z
|
153,716,784 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1468-0289.2011.00617.x",
"MAG": "1912542946",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This Virtual Issue of the Review is offered as a modest contribution towards reigniting interest in macroeconomic policy in Britain between the wars. In reprinting 19 articles which were published in the Review between 1974 and 1991, the introduction to this Virtual Issue supplements those articles and provides a further opportunity to re‐examine key macroeconomic policy episodes and specific policy impact. The articles are divided into three sections: monetary and exchange rate policy; fiscal policy and the Keynesian solution; and tariff policy. The purpose of this introductory essay is to contextualize these articles briefly, comment on subsequent literature, and, where appropriate, point to future, potentially fertile areas for research which will take forward the research findings here reproduced.
|
2022-09-14T06:07:08.272Z
|
120,069,096 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/0256-307X/18/3/319",
"MAG": "1969418974",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We consider a two-dimensional (2D) trapped ion model in which two laser beams drive the corresponding vibrational motions and are carrier resonant with the two-level of the ion. Due to the coherent superposition of two sub-Rabi oscillations involved in the bimodal vibrations, the Rabi frequency degeneration and offset may occur in this model. This provides the possibility of generating the pair coherent state in the 2D trapped ion.
|
2022-09-21T19:36:11.778Z
|
170,983,643 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.18256/2318-1109/ARQIMED.V1N1P31-40",
"MAG": "1581459517",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A area da construcao civil atualmente, no que diz respeito a sustentabilidade, e uma das areas que mais causa impacto ambiental, devido ao fato de ser responsavel por uma das atividades que traz efeitos nocivos e graves para o meio ambiente, uma vez que contribui para a producao de residuos, escassez de recursos naturais, modificacao da paisagem natural, poluicao de ar, agua, entre outros. E de grande porte o desafio o qual o setor enfrenta; apropriar uma atividade de tamanha magnitude com condicoes que a guiem para um desenvolvimento sustentavel. Para se atingir o desenvolvimento sustentavel, e necessario que seja ecologicamente correto, economicamente viavel e unificado ao desenvolvimento social. Neste cenario, o Sistema Light Steel Framing (LSF), surge propondo uma solucao inovadora, aliando o uso da modulacao, a qual permite o controle de utilizacao e a minimizacao no desperdicio dos materiais, conforto termico e acustico, cargas menores das fundacoes, construcao rapida, geracao de ganhos de produtividade, e consequente reducao de custos. O LSF tem boas respostas as exigencias de sustentabilidade e a reducao do desperdicio e de entulhos nos canteiros de obras. O artigo se propoe apresentar um comparativo de viabilidade economica entre o sistema LSF e o sistema convencional para a construcao de 210 habitacoes de interesse social que serao construidas no Loteamento Canaa, pertencente ao bairro Sao Jose, em Passo Fundo – RS.
|
2022-10-11T20:33:25.376Z
|
27,644,955 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1073/PNAS.74.8.3167",
"MAG": "2055499062",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Membrane vesicles prepared from Escherichia coli B/r grown on glutamate as a sole source of carbon and energy require sodium for glutamate accumulation when energized by D-lactate oxidation. Glutamate uptake can also be driven by a prearranged sodium gradient (out to in) in the absence of an energy source or a protonmotive force. Sodium ions are exchanged rapidly in respiring vesicles and the sodium gradient may be large enough under certain conditions to drive glutamate uptake after the protonmotive force is abolished with m-chlorocarbonylcyanide phenylhydrazone. Glutamate uptake due to a prearranged sodium gradient or lactate oxidation is inhibited by monensin but not by nigericin. Transport does not occur in response to valinomycin-induced membrane potential. We interpret these results to indicate that glutamate transport is obligately coupled to sodium transport and can only occur when there is a net flux of sodium ions. This flux is driven by a chemical gradient of sodium that is created by the protonmotive force generated by respiration.
|
2022-10-14T00:51:11.816Z
|
247,855,492 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/alz.12650",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
There is no consensus on which test is more suited to outline the cognitive deficits of cerebral small vessel disease (cSVD) patients. We explored the ability of eight cognitive tests, selected in a previous systematic review as the most commonly used in this population, to differentiate among cSVD patients, controls, and other dementing conditions performing a meta-analysis of 86 studies. We found that cSVD patients performed worse than healthy controls in all tests while data on the comparison to neurodegenerative diseases were limited. We outlined a lack of data on these tests' accuracy on the diagnosis. Cognitive tests measuring processing speed were those mostly associated with neuroimaging cSVD markers. There is currently incomplete evidence that a single test could differentiate cSVD patients with cognitive decline from other dementing diseases. We make preliminary proposals on possible strategies to gain information about the clinical definition of cSVD that currently remains a neuroimaging-based one.
|
2022-11-25T17:40:35.364Z
|
226,295,979 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/acs.biomac.0c01225",
"MAG": "3100733732",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We present a modular platform from which biohybrid protein-polymer nanostructures can be generated in a straightforward and facile manner. Specifically, an aqueous polymerization-induced self-assembly (PISA) AB block copolymerization system was derived from a mutant superfolder green fluorescent protein (sfGFP) as the solvophilic, stabilizing A block. By genetically encoding sfGFP with an isobutyryl bromide functionality, we grafted a quintessential atom-transfer radical polymerization initiation site with hydroxypropyl methacrylate (HPMA) to form the solvophobic B block. Monitoring nanostructure formation using dynamic light scattering, gel permeation chromatography, and transmission electron microscopy revealed uniform micellar morphologies. The radii of the micelles increased with increasing HPMA block length, resulting in nanoparticle sizes ranging from 15 to 48 nm. Solvophilic stabilization afforded by the encoded sfGFP makes this an ideal PISA initiator, and we posit this platform has potential for generating complex biohybrid nanostructures for other protein-polymer systems.
|
2022-11-27T17:41:41.626Z
|
39,616,115 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1103/PHYSREVLETT.70.694",
"MAG": "1989413048",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Sum rules are derived for the circular dichroic response of a core line (CMXD). They relate the intensity of the CMXD signal to the ground-state expectation value of the magnetic field operators (orbital, spin, and magnetic dipole) of the valence electrons. The results obtained are discussed and tested for transition metals and rare earths.
|
2022-12-21T11:42:24.676Z
|
233,795,336 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.47080/PROGRESS.V4I1.1161",
"MAG": "3135692066",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The aim of this research was to developed the learning planning using cooperative integrated reading and composition (CIRC) for teaching basic banking subject in vocational school level. The method in this research used R&D method and using ADDIE model (Analysis, Design, Develop, Implement, Evaluate). But in this research, researcher did not use the Evaluate phase because this research did not measure the effectiveness. The study indicated that based on the results of experts assessments (teacher and lecturer) the learning planning obtain value up to 4,35 and 3,95. Meanwhile, based on the students responses obtain value up to 3,9. So it could be concluded that in general the assessment of learning planning using CIRC Model obtain the good result. Teacher or school could also use this learning planning with CIRC model to teach the students in subject of basic banking for vocational school level.
|
2022-01-27T20:44:11.272Z
|
96,814,454 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1039/C39900000902",
"MAG": "2153224238",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Deuterium labelling experiments show that the title reaction is intramolecular, and does not proceed by rotation of the CHR terminus; a mechanism involving a C-H ‘σ bond complex’ is proposed.
|
2022-02-10T14:04:01.091Z
|
25,830,398 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/13811118.2015.1004471",
"MAG": "1991149527",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This study assesses the complex impact of risk and protective factors on suicide mortality in the Ukrainian general population. Data on suicide rates and socioeconomic and medical factors were obtained from the Ukrainian State Statistical Office, WHO, and the European Social Survey. Structural equation modeling was used for data analysis. Religion and education were negatively associated with suicide. The relationship between drug addiction/alcoholism and suicide was positive. The association between urbanization and suicide mortality was negative. The relationship between gross regional product (GRP) and female suicide was slightly negative. Religiosity was the protective factor most strongly linked with suicide mortality followed by urbanization. The harmful role of drug addiction and alcoholism was confirmed. The role of education and GRP is controversial. No striking gender differences were found.
|
2022-03-16T07:25:05.545Z
|
213,970,305 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1757-899X/671/1/012017",
"MAG": "2999409798",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
To increase the capacity factor of a concentrated solar thermal power plant (CSTPP) beyond the hours of sunlight, the use of thermal energy storage systems (TES) can be a promising solution. Phase change materials (PCMs) can store latent thermal energy in the course of the melting process and release it when solar energy is not available. Generally, PCMs have low thermal conductivity. One of the most commercially promising solutions is the application of an extended heat transfer surface inside the PCM container. Moreover, the distance of the heat transfer fluid (HTF) to the core of the PCM in a TES system can affect the storage performance. Accordingly, a triplex tube heat exchanger with eight fins is considered in this paper, to investigate the impact of the different velocity of HTF and different entrance pattern in a vertical PCM container. Notably, the middle enclosure of the triplex tube is filled with PCM. Numerical analysis using an enthalpy porosity technique revealed that increasing HTF velocity reduces the charging time. Also, when the HTF enters from the bottom of the container, the storage time will diminish owing to a natural convection side-effect, but if the HTF flows downward, the amount of sensible thermal energy storage is higher than in the other cases.
|
2022-07-31T09:25:43.854Z
|
20,677,114 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1371/journal.pone.0180565",
"MAG": "2731640129",
"PubMedCentral": "5500331"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0180565&type=printable"
}
|
Background Glomerular filtration rate (GFR) is essential for renal function evaluation and classification of chronic kidney disease (CKD), while the reference method in children are cumbersome. In the Chinese children, there was no data about GFR measured through plasma or renal clearance of the exogenous markers, and therefore no validated GFR-estimating tools in this population. Methods We measured GFR with double-sample plasma clearance of 99mTc-DTPA (mGFR) in 87 hospitalized children with renal injury. Using mGFR as the golden standard, we evaluate the efficiency of four different GFR estimation equations (the original and update Schwartz equation, the Filler equation, the CKiD equation) by statistical parameters of correlation, precision and accuracy. Results In our population, mGFR was 97.0± 31.9 mL/min/1.73m2. The updated Schwartz equation, the Filler equation and the CKiD equation, produced eGFR with strong correlation with mGFR, strong explanation capacity of variance in mGFR, small bias, satisfactory performance in Bland-Altman analysis, high intra-class correlation coefficients, high ratio of eGFR within mGFR±10% and eGFR within mGFR±30%, good agreement in CKD staging between eGFR and mGFR. The original Schwartz equation produced eGFR with large bias, poor precision and accuracy. Conclusion The validated equations to estimate GFR in our patients are the updated Schwartz equation, which is simple for bedside use, the Filler equation and the CKiD equation, which provide more accurate eGFR. The original Schwartz equation should not be applied to estimate GFR in Chinese children with kidney injuries.
|
2022-09-25T16:44:08.824Z
|
124,477,110 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1063/1.4942787",
"MAG": "2289844350",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
Awe et al. found on the 20 MA Z machine [Acta Phys. Pol. A 115, 956 (2009)] that applying an externally generated axial magnetic field to an imploding liner leads to a helical pattern in the liner when viewed with soft x-ray radiography ([Phys. Rev. Lett. 111, 235005 (2013)] and [Phys. Plasmas 21, 056303 (2014)]). Here, we show that this phenomenon is also observed in extreme ultraviolet self-emission images of 10 mm long cylindrical metal liners having varying diameters and varying wall thicknesses on a 1 MA, 100–200 ns pulsed power generator. The magnetic field in these experiments is created using either twisted return current wires positioned close to the liner, generating a time-varying Bz, or a Helmholtz coil, generating a steady-state Bz.
|
2022-09-30T00:43:28.287Z
|
23,233,418 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/00042560-199608150-00013",
"MAG": "2332252223",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://journals.lww.com/jaids/Fulltext/1996/08150/Human_T_Cell_Lymphotropic_Virus_Type_I_Infection.13.aspx"
}
|
Forty-one human T-cell lymphotropic virus type I (HTLV-1)-seropositive individuals were identified among 1,012 subjects with stored serum samples from a health and seroepidemiological survey conducted in Barbados in 1972. These 41 subjects plus 79 HTLV-1 seronegative household members were targeted in a follow-up study 20 years later. Sixteen seropositive subjects and 22 seronegative subjects were interviewed, examined, and phlebotomized. There were no changes in HTLV-1 serostatus between the 1972 and follow-up serum samples. Three (19%) of the seropositive subjects had HTLV-1-associated disorders: two with dermatitis and one with "smoldering" adult T-cell leukemia. Neurologic and immunologic function was similar in HTLV-1-seropositive and HTLV-1-seronegative subjects. HTLV-1 antibodies persist over many years, and the risk for seroconversion of household contacts is low.
|
2022-10-28T00:44:36.710Z
|
129,905,452 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1029/JD090ID03P05857",
"MAG": "1968968388",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
During the last two decades, ice has been recognized as a hindered ferroelectric, i.e., a substance that is supposed to be ferroelectric at 0°K, but turns out to have the protonic disorder frozen in, and to persist in a me tas table finite-entropy state down to arbitrarily low temperatures. Small, heterogeneously nucleated aggregates of water and ice may therefore be saturation - polarized and may keep most of their polarization while they grow, perhaps up to sizes of the order of 1 μ for water and more than 10 μ for ice crystallites. This upper size limit is likely to increase with the growth rate. More important, if the criterion Nν2 > 2.5 1021cm−3 is satisfied, a polarization catastrophe occurs, rendering the cloud ferroelectric. Here N is the concentration of aggregates, ν the number of H2O molecules in each. The direction of the spontaneous polarization is usually determined by the fair-weather field vector, leading to negative polarization charges on top of the cloud and positive on the lower end of the polarization catastrophe region. Masking charges of opposite sign accumulate in these regions during the formation of the cloud, compensating most of the polarization charges. When the aggregates grow too large, they lose their dipole moment, i.e., when the cloud dissipates, the polarization catastrophe disappears, and the masking charges generate lightning if the process of dissipation is fast.
|
2022-12-13T20:47:13.587Z
|
53,344,143 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2307/1142579",
"MAG": "51835768",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://scholarlycommons.law.northwestern.edu/cgi/viewcontent.cgi?article=6131&context=jclc"
}
|
bargaining-the process by which the state grants sentencing and other concessions in exchange for guilty pleas in criminal cases-is frequently paramount in this concern for crime control and justice. Yet despite the general recognition of the importance of plea bargaining to American jurisprudence, disagreement persists about what plea bargaining should accomplish given prevailing norms of justice, what plea bargaining actually does accomplish given the reality of the judicial process, and how the existing practice could be modified (or preserved) through public policy. Research reported in this study addresses these concerns by posing and answering a broad question: Who gains and who loses from plea bargaining? Based on data contained in the Prosecutor's Management Information System (PROMIS) maintained by the United States Attorney's Office in Washington, D.C., the analysis is essentially empirical, and the attempt to quantify observations and support conclusions statistically contrasts with an equally important existing body of research, which is more qualitative.
|
2022-12-16T20:08:26.162Z
|
25,399,048 |
{
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"ArXiv": null,
"DOI": "10.1097/00132586-199010000-00029",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Serial electrocardiograms were obtained on 93 healthy ASA physical status I and II term parturients during nonemergent cesarean delivery under regional anesthesia. Electrocardiographic changes occurred in 44 of the 93 patients (47.3%); in 35 of these 44 patients, the changes were characteristic, or suggestive, of myocardial ischemia. Symptoms of chest pain, pressure, and dyspnea occurred in 15 of the 44 patients with electrocardiographic changes; no patient without electrocardiographic change developed symptoms of chest pain, pressure, or dyspnea. Small but statistically significant differences were noted in heart rate, diastolic and systolic arterial pressures, and rate-pressure product between the patients with electrocardiographic changes and those without. The authors speculate that myocardial ischemia is a likely cause of both the electrocardiographic changes seen in these patients and of the symptoms of chest pain and dyspnea that they sometimes experience.
|
2022-12-18T13:57:33.778Z
|
54,926,707 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1142/S1402925112400104",
"MAG": "1985530175",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We prove the existence of solitary traveling wave solutions for an equation describing the evolution of the free surface for waves of moderate amplitude in the shallow water regime. This nonlinear third-order partial differential equation arises as an approximation of the Euler equations, modeling the unidirectional propagation of surface water waves. We give a description of the solitary wave profiles by performing a phase plane analysis and study some qualitative features of the solutions.
|
2022-12-21T19:59:05.373Z
|
149,041,984 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.26699/jnk.v4i2.art.p093-097",
"MAG": "2928210291",
"PubMedCentral": null
},
"license": "CCBYSA",
"status": "GOLD",
"url": "http://jnk.phb.ac.id/index.php/jnk/article/download/0171/pdf"
}
|
Midwifery student were lack of motivation and confidence. Though both of these were the most important thing to be possessed by the student of midwifery as the preparation for the exams because this midwifery student will become the health care employee especially women. This study aimed to analyze the correlation between motivation and self-efficacy with physical examination test result. This study was observational analitic study using cross-sectional approach. The sampel was 34 3rd grade students in D III Midwivery Department on STIKes Patria Husada Blitar, using total sampling. The dependent variable was the physical examination test result, while the independent variables were motivation and self efficacy. The data was analyzed using multiple linear regression model. 1) There were positive correlation and statistically significant between motivation and test result of a physical examination (b=0.35; CI 95% 0.043 s.d. 0.65; p = 0.027). 2) There were positive relationship and statistically significant between self-efficacy and test result of a physical examination(b = 0.44, CI 95% 0.17 s.d. 0.71; p = 0.003). There were positive relationship and statistically significant correlation between motivation and self-efficacy with physical examination test result. Motivation and self-efficacy can increase exam result.
|
2022-10-14T00:31:49.147Z
|
30,604,299 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1620/TJEM.104.25",
"MAG": "2103199467",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The latest techniques in scanning electron microscopy have been applied to this study. In cholesterol gallstones, the fracture surface generally shows a crystalline plane radiating pattern, often showing dendritic growth, around the nucleus. On the surface or fracture plane of a cholesterol stone, parallelogram crystals or corrugated crystals are sometimes seen. In higher magnification, the surface of a crystalline plane is seen to be composed of lamellae of about 200 A in thickness, which is frequently associated with spiral growth. In view of the fact that a number of linear boundaries are just visible near the center of each spherulite, it appears that, in the multinuclear stones, cyrstallization starts at various points or nuclei and spreads out from these points. These results support the view that cholesterol crystals proceed from the center toward the periphery.
|
2022-10-08T15:03:51.324Z
|
5,013,988 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1515/rrlm-2017-0008",
"MAG": "2621345550",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://content.sciendo.com/downloadpdf/journals/rrlm/25/2/article-p202.pdf"
}
|
Cervical cancer, statistically, occupies the fourth place worldwide among cancers in women in term of incidence and mortality; most of the cases are discovered in developing countries (1). Its etiology is related to Human papillomavirus (HPV) infection, a necessary, but insufficient cause of most of the cervical cancers, but also for a high proportion of vulva, vagina or anal cancers, and some of the oropharyngeal cancers (2). Currently, more than 200 HPV subtypes have been isolated, and more than 40 different HPV types are found in the genital tract or perianal region (3). The condition of HPV infection to cause a cervical cancer is to become persistent and to escape from the immune defence of the host. Data about the frequency of HPV infection in Romanian population are scanty. Only few studies have been done (4-7), and they focused mainly on cytological abnormalities and pre-invasive cervical lesions, but not in invasive cervical cancer. Thus, the goal of our research was to obtain preliminary information about the frequency of HPV infection and the HPV genotypes in a Romanian population with invasive cervical cancer. The samples included 80 histologically confirmed invasive cervical cancer fresh specimens of previously non-irradiated Romanian women, collected between September 2015 and October 2016 in a tertiary university hospital. The Ethics Committee of the hospital approved the study protocol. The patients were staged according to the International Federation of Gynecology and Obstetrics (FIGO) staging. All specimens were collected with PreservCytT and stored at +4°C until analysed. Detection consisted in genomic DNA extraction from cervical epithelial cells, PCR amplification of target DNA (37 HPV genotypes including 13 high risk genotypes: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68), hybridization of PCR products with oligonucleotide probes on solid strips and colorimetric identification of hybridization productsaccording to manufacturer recommendations (LINEAR ARRAY HPV Genotyping Test, Roche). A chi square test and a logistic regression were performed to try to find a correlation between HPV type, stage of disease, or histological type. Statistical analyses for P values were performed using 2 × 2 contingency tables, with two-tailed P values calculated using the Fisher exact test. All p <0.05 were considered statistically significant. The patients’ mean age at the time of diagnosis was 49 years (between 28 and 68 years old). The majority of histological diagnoses were squamous cell carcinoma (75 out of 80 patients, 93.75%), with 4 adenocarcinomas (5%) and one neuroendocrine carcinoma. Forty-one patients (51.25%) were stage I (Ia1-Ib2), 24 (30%) stage II, 14 (17.5%) stage III, and one (1.25%) was staged IVa. Of the 80 samples analyzed, 10 cases (12.5%) were negative for HPV-DNA. Most of HPV-DNA positive cervical cancer patients harboured single infections (87.14%); 7 patients had two HPV types (10%); and in 2 patients (2.86%), three different HPV types were identified. HPV16 was the most frequent type, with 72.5% relative contribution as single (58 patients) or multiple infection (2 cases of double infection and 2 patients harbouring three different HPV types). Other two HPV double infections harboured HPV31 associated with HPV39 and HPV73. Interestingly, HPV18 Letter to the Editor
|
2022-03-02T14:25:28.516Z
|
22,310,366 |
{
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"ArXiv": null,
"DOI": "10.1177/1460458213518545",
"MAG": "2087410954",
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},
"license": null,
"status": null,
"url": null
}
|
Our interest here is with the ‘marriage’ of e-patient information systems with care pathways in order to deliver integrated care. We report on the development and implementation of four such pathways within two National Health Service primary care trusts in England: (a) frail elderly care, (b) stroke care, (c) diabetic retinopathy screening and (d) intermediate care. The pathways were selected because each represents a different type of information and data ‘couplings’, in terms of task interdependency with some pathways/systems reflecting more complex coordinating patterns than others. Our aim here is identify and explain how health professionals and information specialists in two organisational National Health Service primary care trusts organisationally construct and use such systems and, in particular, the implications this has for issues of professional and managerial control and autonomy. The article is informed by an institutionalist analysis.
|
2022-11-20T18:20:22.016Z
|
191,990,279 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.14198/ITACA2014.5.12",
"MAG": "2017777947",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
El present estudi ofereix una analisi de la recepcio critica de l'obra Crim de Germania, de l'escriptor valencia Josep Lozano, publicada per primera vegada a l'abril de 1980 per l'editorial Tres i Quatre, que permet fixar els elements a l'entorn dels quals s'ha anat elaborant la lectura de la novel·la i la seua evolucio temporal. Durant mes de trenta anys, Crim de Germania ha sigut objecte de nombroses valoracions critiques a la premsa i en publicacions periodiques de diversa indole a tot arreu dels territoris de parla catalana. L'estudi s'ha dividit en tres etapes: la primera s'inicia amb la publicacio del llibre i conclou l'any 1981; la segona compren el periodo des de 1982 fins al 2004, i, la tercera, des de 2005 - any en que la novel·la s'amplia i es reedita per Bromera - fins l'actualitat.
|
2022-02-11T00:44:47.755Z
|
56,115,401 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21474/IJAR01/841",
"MAG": "2486845282",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Syarifuddin Hasyim The result of study shows that there is an overlapping arrangement on regional spatial. It is caused by no confirm authority between provinces and districts in regional, or more regulations on the same object such as location license and right on the land, license of nuisance act, and license of building on regional investment project. The act will be definitely confronted with regional town planning. As the result, deviation of land function cannot be avoided so that farm land will be changed to industrial land. It is caused by weakness of law enforcement and ineffective control of government as well as lack of people participation in arranging the regional town planning.
|
2022-02-11T19:34:58.192Z
|
121,398,483 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1121/1.1981359",
"MAG": "2023421630",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://asa.scitation.org/doi/pdf/10.1121/1.1981359"
}
|
A small but significant negative threshold shift (decrease in hearing threshold) has been reported following particular sound exposures and has been called sensitization. Similar negative threshold shifts of 2 to 3 dB have been observed in experiments of similar design but with a period of quiet substituted for the sound exposure. This negative shift following what amounts to an interruption in threshold tracking was the dependent variable in this series of three experiments concerned with temporal independent variables. The test tone was a continuous tone of 500 Hz. Threshold was tracked using a recording attenuator. As the interrupting quiet period was lengthened from 1 to 4 min the magnitude of the negative shift increased from 2 to 4 dB. In a 14‐min tracking session during which seven tracking periods were interrupted by 1‐min quiet intervals, the negative shift was maximum at the outset but still was increasing at the end of the session. Finally, 1 h of isolation in a sound‐treated room prior to expe...
|
2022-07-04T21:06:00.823Z
|
23,950,412 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/GEPI.1370120604",
"MAG": "1582917859",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Problem 1 consisted of artificial data simulated from an oligogenic (four‐locus) disease model. The data set contained 200 nuclear families with at least one affected child and 100 control families with no affected members. Two of the disease loci were intended to be detectable via association analysis but not necessarily via linkage analysis, and the other two were virtually undetectable in this data set. Participants used association analysis, linkage analysis, and segregation analysis to analyze these data. Their findings are summarized, and analysis strategies are discussed. ©1995 Wiley‐Liss, Inc.
|
2022-09-07T06:44:18.374Z
|
111,060,020 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1680/CIEN.2010.163.6.33",
"MAG": "2110462328",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The Almas Tower is a 360 m high office tower in Dubai, UAE. The design comprises two intersecting elliptical towers located on a sculpted three-storey podium. The architectural form and client's requirement for floor efficiencies of 80% resulted in significant challenges for the structural design team. This paper discusses the structural framing adopted, wind-tunnel studies undertaken – including building acceleration, lateral movements and column-shortening effects – and mitigation measures introduced. It also describes the design of the tower's spire, which features tuned mass dampers.
|
2022-09-12T12:58:35.265Z
|
139,165,513 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.12783/DTETR/OECT2017/16110",
"MAG": "2887182837",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Considering the real-time requirement of the target recognition task, a kind of micromotion feature extraction method in low pulse repetition frequency(PRF) with multi-beam is proposed. Firstly, the transmitting waveform is designed and the multi-target observation is achieved. And then, considering the performance of target tracking, the time series of transmitting pulses is designed in low PRF. At last, the OMP algorithm is used and the micromotion feature of targets in different directions is extracted successfully by directly using the narrowband tracking pulses, which has improved the working efficiency of the radar and the real-time ability of the target recognition task. The simulation has proved the performance of the algorithm in low SNR circumstance. Introduction Recently, micromotion feature extraction has become a hot research area [1-3] . However, to accomplish the micromotion feature extraction by using existing algorithms, radar needs to transmit signal pulses specially and can only deal with the targets in one direction at one time, which will cause large resource consumption and poor real-time performance. Through optimizing the transmitting waveform, MIMO radar can transmit the signals that possess the required beam pattern to achieve the simultaneous observation and tracking of the targets in different directions [4-6] . In general, MIMO radar transmits narrow-band signals for target tracking, and the pulse repetition period of the tracking pulses is long. If we directly use time-frequency analysis technique to extract the micromotion feature of the targets based on the tracking pulses, the frequency aliasing will happen. Therefore, it is essential to study on the micromotion feature extraction method in low PRF. In the paper, a kind of micromotion feature extraction method in low PRF is proposed. The transmitting waveform is designed and the multi-target observation is achieved. And considering the performance of target tracking, the time series of transmitting pulses is designed. At last, by directly using the narrowband tracking pulses the micromotion feature of targets in different directions is extracted successfully. MIMO Radar Waveform Design Suppose the MIMO radar emitter array is consisted of M linearly spaced isotropic array elements and the inter-element spacing is d . The transmitting signal synthesized at the angle θ can be denoted as
|
2022-09-13T22:04:40Z
|
115,132,396 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.7508/JNS.2014.01.002",
"MAG": "2298159896",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Some issues; leakage, tunneling currents, boron diffusion are threatening SiO2 to be used as a good gate dielectric for the future of the CMOS (complementary metal- oxide- semiconductor) transistors. For finding an alternative and novel gate dielectric, the NiO (Nickel oxide) and PVA (polyvinyl alcohol) nano powders were synthesized with the sol-gel method and their nano structural properties were studied using the X-ray diffraction (XRD), Atomic force microscopy (AFM), Scanning electron microscopy (SEM), UV-Vis spectrophotometer and GPS 132 techniques. The obtained results indicated that the sample (5 g NiO and 0.02g PVA prepared at 30˚C, annealed in an oven at a temperature of 80˚C) can fill this gap due to its higher dielectric constant, better morphology, less rough surface and less leakage current.
|
2022-09-23T17:41:44.597Z
|
144,345,763 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3917/MED.159.0059",
"MAG": "2061286627",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Si les ONG tendent a ressembler de plus en plus a des entreprises par leur taille, leur fonctionnement et les outils qu'elles leur empruntent, est-il possible pour autant d'envisager le management strategique de ces organisations comme celui des entreprises commerciales ? Les caracteristiques des ONG impliquent-elles un processus different dans l'elaboration et la mise en oeuvre de leur strategie ? Quels sont alors les elements a retenir dans l'analyse de leur management strategique qui permettent d'apprehender leur situation de gestion ? Cet article apporte des reponses a ces questions, qui impliquent de s'interesser au management strategique des ONG humanitaires afin de determiner dans quelle mesure les approches gestionnaires sont pertinentes pour proceder a une analyse manageriale des ONG, quelles sont les principales composantes du management strategique des ONG ainsi que les principales sources et caracteristiques de leur legitimite et le role qu'elle tient dans leur management strategique. Enfin, la conclusion propose un schema de synthese du management strategique des ONG etablissant le lien entre ces differentes composantes, le processus d'accountability et la legitimite qui en resulte.
|
2022-10-07T00:18:46.566Z
|
32,422,998 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1308/003588412X13373405385214f",
"MAG": "2075714945",
"PubMedCentral": "3954386"
},
"license": null,
"status": null,
"url": null
}
|
BACKGROUND T-tube placement following bile duct exploration remains commonplace.1 Via an unobstructed T-tube tract, choledochoscopic removal of retained biliary stones has become a well established mode of treatment, having been used as early as 1982.2 However, T-tubes or reinserted straight drainage tubes after choledochoscopy are displaced frequently by accident, which results in sinus tract occlusion.3 Generally, an emergency reoperation or endoscopic retrograde cholangiopancreatography (ERCP) may be necessary if the T-tube tract cannot be recanalised promptly. We describe a new technique to reinsert the drainage tube and recanalise the T-tube sinus tract before its complete closure.
|
2022-12-12T04:07:03.545Z
|
15,288,828 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1534/genetics.108.090894",
"MAG": "2062164239",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc2535705?pdf=render"
}
|
The genetic basis of prion disease incubation time is principally determined by polymorphisms in the prion protein gene, Prnp. However, it is now known that other genetic factors are important. Several quantitative trait loci (QTL) have been identified across the genome including a broad region of linkage on Mmu11. Monocyte chemoattractant protein 1 (MCP-1) maps to this region and has been associated with microglial activation and reduced survival in the ME7 mouse scrapie model of prion disease. We have identified 10 polymorphisms, 3 of which are nonsynonomous, in Mcp1 between “long” (CAST) and “short” (SJL or NZW) incubation-time mouse strains. Crosses between these strains and Mcp1−/− mice inoculated with the Chandler/RML mouse scrapie prion strain formed the basis of a quantitative complementation test. In these models loss of Mcp1 did not show an increase in incubation time suggesting that the effects of Mcp1 may be specific to the ME7 prion strain and that Mcp1 does not contribute to the QTL described on Mmu11.
|
2022-12-16T01:47:00.130Z
|
207,599,570 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3852/11-219",
"MAG": "2138673539",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Two new species of Ramicandelaber isolated from soil in Taiwan are described. Ramicandelaber fabisporus sp. nov. is characterized by having bean-shaped spores that are the smallest in the genus and also by the absence of lateral branches on the sporangiophores. Ramicandelaber taiwanensis sp. nov. is characterized by small, fusiform spores and it produces lateral branches that arise from the sporangiophores. Morphological characters and molecular phylogenetic analysis (D1/D2 domains of the LSU rRNA genes and ITS region) justify these new species of Ramicandelaber. A key is provided to the recognized species of Ramicandelaber.
|
2022-12-20T04:17:08.158Z
|
95,811,344 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/APP.11570",
"MAG": "2013016467",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Liquid propylene was polymerized in a 5-L autoclave batch reactor using a commercially available TiCl4/MgCl2/Al(ethyl)3/DCPDMS Ziegler-Natta catalyst, with a phthalate ester as internal electron donor. The powders from these polymerizations were characterized using laser diffraction particle size distribution (PSD) analysis, scanning electron microscopy (SEM), and bulk density measurements. These characteristics were analyzed as a function of the process conditions, including hydrogen and monomer concentration, polymerization temperature, and the prepolymerization method. It was shown that polymerization temperature influences the powder morphology to a large extent. At low temperatures, high-density particles were obtained, showing regular shaped particle surfaces and low porosities. With increasing temperature, the morphology gradually was transferred into a more open structure, with irregular surfaces and poor replication of the shape of the catalyst particle. When using a prepolymerization step at a relatively low temperature, the morphology obtained was determined by this prepolymerization step and was independent from conditions in main polymerization. The morphology obtained was the same as that observed after a full polymerization at temperature. Even when using a short polymerization at an increasing temperature, the morphology was strongly influenced by the initial conditions. The effect of variation in hydrogen concentration supported the conclusion that the initial polymerization rate determines the powder morphology. In the absence of hydrogen, high bulk densities, and regularly shaped particles were obtained, even at high temperatures. With increasing hydrogen concentration, the reaction rates increased rapidly, and with that changed the morphology.
|
2022-12-21T00:29:57.709Z
|
211,945,562 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/oxfordhb/9780190675233.013.36",
"MAG": "2980523040",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://philpapers.org/archive/FRECAE-5.pdf"
}
|
There is an existing debate regarding the view that technological instruments, devices, or machines can assert or testify. A standard view in epistemology is that only humans can testify. However, the notion of quasi-testimony acknowledges that technological devices can assert or testify under some conditions, without denying that humans and machines are not the same. Indeed, there are four relevant differences between humans and instruments. First, unlike humans, machine assertion is not imaginative or playful. Second, machine assertion is prescripted and context restricted. As such, computers currently cannot easily switch contexts or make meaningful relevant assertions in contexts for which they were not programmed. Third, while both humans and computers make errors, they do so in different ways. Computers are very sensitive to small errors in input, which may cause them to make big errors in output. Moreover, automatic error control is based on finding irregularities in data without trying to establish whether they make sense. Fourth, testimony is produced by a human with moral worth, while quasi-testimony is not. Ultimately, the notion of quasi-testimony can serve as a bridge between different philosophical fields that deal with instruments and testimony as sources of knowledge, allowing them to converse and agree on a shared description of reality, while maintaining their distinct conceptions and ontological commitments about knowledge, humans, and nonhumans.
|
2022-12-22T06:28:45.296Z
|
137,073,599 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4028/www.scientific.net/AMR.97-101.1677",
"MAG": "1974998981",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
TiO2-g-Polystyrene(PS) nano-microspheres were prepared by grafted styrene monomer on the surface of nano-TiO2 particles via emulsion polymerization, and its surface and morphology were studied by Transmission electron microscopes(TEM), Fourier transform infrared spectroscopy(FTIR) and thermal gravimetric analysis(TGA). The results showed that the TiO2-g-PS nano-microsphere had a structure of sphericity composed of TiO2 and PS as core and shell respectively. The core-shell nanoparticles were subsequently used as filler in a PS matrix, and the impact strength of the TiO2-g-PS/PS composites were studied. The results showed that the impact strength of the composite material could be improved obviously, the maximum value of impacted strength of the TiO2-g-PS/PS was 1.75kJ/m2, which was 180% higher than that of pure PS. Drawing from the results, it could be confirmed that these core-shell TiO2-g-PS nanosphere fillers could toughen the PS matrix.
|
2022-01-27T12:11:35.391Z
|
97,133,382 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/IC00281A001",
"MAG": "2092508818",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
[Mn 4 (μ 3 -O) 2 (O 2 CCPh 3 ) 6 (OEt 2 ) 2 ] cristallise dans le systeme monoclinique, groupe d'espace P2 1 /n et sa structure est affinee jusqu'a R=0,068
|
2022-09-14T19:29:40.426Z
|
118,646,610 |
{
"externalids": {
"ACL": null,
"ArXiv": "0908.3754",
"DOI": "10.1103/PhysRevA.80.040501",
"MAG": "2018815955",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The two-loop self-energy correction to the ground-state Lamb shift is calculated for hydrogenlike ions with the nuclear charge Z=10-30 without any expansion in the binding field of the nucleus. A calculational technique is reported for treatment of Feynman diagrams in the mixed coordinate-momentum representation, which yields significant improvement in numerical accuracy as compared to previous results. An extrapolation of the all-order numerical data yields a result for the higher-order remainder function for hydrogen. The previously reported disagreement between the all-order and the perturbative approaches is reduced to the marginal agreement.
|
2022-10-25T10:49:39.713Z
|
237,197,497 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1073/pnas.2100579118",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://www.pnas.org/content/pnas/118/34/e2100579118.full.pdf"
}
|
Significance Many autism risk genes, such as Syngap1, regulate synapse plasticity, and disruptions to this subcellular process are thought to underlie behavioral deficits. However, behavior emerges through experience-driven dynamics within neural ensembles or groups of coactivated neurons. It is currently unclear how genetic regulation of synapse plasticity contributes to experience-dependent changes to cortical ensemble activity. Our data demonstrate that disruptions to synapse-level strengthening mechanisms in Syngap1 mice underlies impairments to balanced plasticity within cortical ensembles driven by novel sensory experience. Because not all neurons in ensembles were sensitive to Syngap1 regulation, we propose that additional genetic mechanisms are also initiated in response to experience to effectively redistribute activity within cortical networks. A significant proportion of autism risk genes regulate synapse function, including plasticity, which is believed to contribute to behavioral abnormalities. However, it remains unclear how impaired synapse plasticity contributes to network-level processes linked to adaptive behaviors, such as experience-dependent ensemble plasticity. We found that Syngap1, a major autism risk gene, promoted measures of experience-dependent excitatory synapse strengthening in the mouse cortex, including spike-timing–dependent glutamatergic synaptic potentiation and presynaptic bouton formation. Synaptic depression and bouton elimination were normal in Syngap1 mice. Within cortical networks, Syngap1 promoted experience-dependent increases in somatic neural activity in weakly active neurons. In contrast, plastic changes to highly active neurons from the same ensemble that paradoxically weaken with experience were unaffected. Thus, experience-dependent excitatory synapse strengthening mediated by Syngap1 shapes neuron-specific plasticity within cortical ensembles. We propose that other genes regulate neuron-specific weakening within ensembles, and together, these processes function to redistribute activity within cortical networks during experience.
|
2022-12-16T07:18:20.872Z
|
20,625,501 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3109/02713689008999568",
"MAG": "2087375818",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Regular injections of the gliotoxins D-alpha-aminoadipic acid and L-alpha-aminoadipic acid were made into the vitreous chamber of the eyes of newly-hatched chicks reared either in a normal visual environment or under conditions of monocular occlusion. Striking differences in the growth rates of the eyes from the different groups were observed. Injection of D-alpha-aminoadipic acid, which causes the Müller glial cells to swell and diminishes the retinal OFF-response, resulted in a marked increase in the rate of axial growth of the eye compared with normal eyes. However, injection of D-alpha-aminoadipic acid into occluded eyes caused a lesser growth rate than was observed in occluded control eyes. By contrast, injection of L-alpha-aminoadipic acid, which also causes severe glial swelling and abolishes the retinal ON-response, caused reduced eye growth in non-occluded eyes. However, injection of L-alpha-aminoadipic acid into occluded eyes caused eye growth in excess of that recorded in the occluded controls. We concluded that the different growth rates observed is more likely a result of the disruption of the neural ON and OFF mechanisms than of the indisposition of the Müller cells.
|
2022-12-16T23:14:35.327Z
|
120,089,075 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1364/LS.2009.LSTUA4",
"MAG": "1974217096",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We show that arbitrary functions of continuous variables can be used to generate tests of local hidden variable theories. The effect of nonideal detectors and noise is included, revealing that optimized functional inequalities are robust.
|
2022-12-19T21:35:55.693Z
|
223,871,083 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3760/CMA.J.ISSN.1005-8559.2006.03.038",
"MAG": "3031239898",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
2004年中国青少年犯罪的统计资料表明:近年来,青少年犯罪总数占全国刑事总数的70%以上,其中十五、六岁青少年犯罪案件又占到青少年犯罪案件总数的70%以上[1].目前,人们把青少年犯罪归结为主体因素、家庭因素、学校因素、社会因素等因素的诱发物.发生犯罪的内在机理归纳为:社会基本矛盾是青少年犯罪的根本因素;外在环境和条件是青少年犯罪的诱发因素;权益侵害是青少年犯罪的激活因素;个体因素是青少年犯罪的调节因素。
|
2022-01-24T18:57:36.595Z
|
228,859,277 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.22229/stc1122020",
"MAG": "3098295210",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Counseling skills courses serve as a foundation upon which counselors-in-training (CITs) build their professional skills and identity. However, basic skills courses also often ignite pervasive anxiety in CITs, which can hinder skill development. The present manuscript presents experiential tools to use in counseling skills courses to effectively combat CIT anxiety: setting the groundwork with clear expectations of CIT performance, anxiety-reducing activities, and facilitating experiential role play activities. An accompanying figure and sample class schedule demonstrate a conceptual framework for intentionally infusing each of these three components into counseling skills courses to reduce pervasive anxiety in CITs.
|
2022-01-27T06:28:58.905Z
|
121,051,415 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1121/1.2935810",
"MAG": "2028016533",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Consonant gradation is a feature of Sami and is realised in Northern Sami in changes from nominative singular to genitive plural form, e.g., “heavdni” (spider) and “heavnni‐t” (spiders). The data examined in this paper was collected in 2007 and represents the first acoustic analysis of consonant gradation in Northern Sami. The data was collected in Ovre Soppero in Northern Sweden using an elicitation technique that was designed to collect phonetically controlled material for analysis. The nouns were elicited in singular or plural form using picture prompts and the participants were asked to give the word in the carrier sentences “Lea okta __ govas” (“There is a ___ in the picture”) and “Leat guokte __ govas” (“There are two ___ in the picture”). The recordings were labeled in Wavesurfer at a phonetic level and the segments relating to consonant gradation extracted for acoustic analysis. In the paper we present our initial findings.
|
2022-02-09T20:26:16.180Z
|
80,023,573 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2217/EBO.11.3",
"MAG": "2718108481",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Saby George is Assistant Professor of Oncology at Roswell Park Cancer Institute, Buffalo, NY, USA. He received his medical degree from Kottayam Medical College, India, internal medicine training from Wright State University, OH, USA, experimental therapeutics training from Cleveland Clinic, OH, USA and medical oncology training from the University of Texas Health Science Center at San Antonio, TX, USA. His area of research and expertise includes clinical trials and translational studies in kidney and prostate cancers.
|
2022-02-11T03:31:48.865Z
|
196,928,131 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/CHIN.200713189",
"MAG": "2949598564",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The one-pot transformation of α-amino acid into β-amino acid derivatives is described. The application of this method to the synthesis of modified dipeptides was also illustrated.
|
2022-02-08T06:51:39.398Z
|
243,486,133 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.31510/infa.v18i1.1162",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://revista.fatectq.edu.br/interfacetecnologica/article/download/1162/657"
}
|
Os estudos sobre Gestão de Pessoas e Gestão do Conhecimento nas organizações apontam os mesmos como fatores decisivos na competitividade no atual mercado globalizado. As condições capacitadoras propiciadas por uma boa gestão de pessoas e gestão do conhecimento, permitem que as organizações tenham ideia de como aumentar a criação e a disseminação do conhecimento a fim de manter a vantagem competitiva. Este trabalho terá como o objetivo conhecer a nova lógica de gestão das pessoas nas organizações em busca do conhecimento e os novos papéis que os trabalhadores assumem nesse contexto como diferencial competitivo. Através de pesquisa bibliográfica foram apresentados os conceitos de gestão de pessoas, gestão do conhecimento, capital intelectual e também exemplos bem sucedidos de uma boa gestão nesse tema. Ao final foi possível constatar que as organizações entendem que a gestão de pessoas quando bem executada torna-se um diferencial competitivo em diversos setores.
|
2022-08-20T10:39:18.530Z
|
39,014,606 |
{
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"ArXiv": null,
"DOI": "10.1080/104732200301728",
"MAG": "2318401514",
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},
"license": null,
"status": null,
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}
|
An environmental-justice (equity) grant program was used to make accessible an existing lead-training program to minority persons and residents of low-income communities. The purpose of the program was to enhance the knowledge base within the communities concerning lead hazards and intervention strategies and expand possibilities for employment in the lead abatement industry. Barriers to attendance were anticipated and addressed, and included transportation, meals, license application fees, reminders of course date and location, and day care. The program was evaluated through measures of recruitment rates, pre- and post-testing scores, and change in perception of confidence at pre-test, post-test, and at four-month follow-up. Fee-paying registrants over the same time period were used as a comparison group. First day attendance rates for individuals recruited into the equity-grant was 59 percent, of these 94 percent completed all days. Equity and fee-paying groups had similar scores on the pre-test (p = .209), while mean scores on the final exam differed significantly (p < .001) between the groups and were 77 percent and 85 percent, respectively. After adjusting for demographic and course type attended, perceptions of self-efficacy (benefit) and outcome-effectiveness (confidence) increased significantly from pre- to post-tests for both groups and remained at post-course levels at four months follow-up. Lessons learned include: (1) Lead abatement and other related activities can be successfully taught through traditional training methods; (2) A necessary element for delivery of educational services to minority groups is forming workable ties with local community groups, but eligibility requirements must be maintained; (3) Once barriers to first-day attendance are overcome, the information necessary to perform specific work skills can be taught; (4) Positive changes in belief are not dependent on minority status, income, or education levels; (5) Training and education increased confidence in ability to perform learned skills, and belief that there will be a beneficial outcome when performed for themselves, their families, and communities; and, (6) A consensus regarding applicability of regulations must be achieved among federal, state, and local communities.
|
2022-08-25T00:36:59.755Z
|
136,788,013 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/PI.4980220402",
"MAG": "2117724364",
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},
"license": null,
"status": null,
"url": null
}
|
The study of polymer interfaces is of prime importance in the field of tyre technology due to the critical role these contribute to tyre operation. The paper reviews the main polymer interfaces present in a tyre—(1) tyre/road (tyre wear or abrasion; tyre traction/skid resistance); (2) polymer/filler (carbon black; silica); (3) polymer/cord (brass coated steel wire; textile—rayon, nylon, polyester, aramid); (4) compound/compound (tack); (5) tyre/air (oxygen/ozone protection)—with respect to the criteria required, physical and chemical, to achieve optimum performance.
|
2022-09-05T08:15:17.834Z
|
118,498,988 |
{
"externalids": {
"ACL": null,
"ArXiv": "1203.0205",
"DOI": "10.1143/JPSJ.81.044002",
"MAG": "2014093170",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper investigates the polytropic matter shell collapse in the non-commutative Reissner–Nordstrom geometry. Using the Israel criteria, equation of motion for the polytropic matter shell is derived. In order to explore the physical aspects of this equation, the most general equation of state, p = k ρ (1+1/ n ) , has been used for finite and infinite values of n . The effective potentials corresponding to the equation of motion have been used to explain different states of the matter shell collapse. The numerical solution of the equation of motion predicts collapse as well as expansion depending on the choice of initial data. Further, in order to include the non-commutative correction, we modify the matter components and re-formulate the equation of motion as well as the corresponding effective potentials by including non-commutative factor and charge parameter. It is concluded that charge reduces the velocity of the expanding or collapsing matter shell but does not bring the shell to static position. ...
|
2022-09-09T03:55:48.633Z
|
23,969,993 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CEC.2008.4631183",
"MAG": "2017697220",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper describes an approach for the optimization of parallel hybrid electric vehicle (HEV) component sizing using particle swarm optimization (PSO) algorithm. In this study, the fitness function is defined to minimize the vehicle engine fuel consumption (FC) and emissions. The driving performance requirements are then considered as constraints. Finally, the optimization process is performed over the test procure TEST CYCLE HYWT, in which a vehicle model named ADVISOR is used as the analysis tool. The results from the computer simulation show the effectiveness of the approach and reduction in FC, emissions while ensuring that the vehicle performance is not sacrificed.
|
2022-10-19T14:22:19.552Z
|
38,320,043 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1089/nat.2014.0516",
"MAG": "1832431046",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Nucleoside analogues are the most promising drugs for the treatment of pancreatic cancer to date. However, their use is often limited due to toxic side effects. Aptamer-mediated targeted delivery of these drugs to cancer cells could maximize their effectiveness and concomitantly minimize the toxic side effects by reducing uptake into normal cells. Previously, we identified a pancreatic cancer-specific, nuclease-resistant RNA aptamer, SQ2, which binds to alkaline phosphatase placental-like 2 (ALPPL2), a putative biomarker for pancreatic cancer. In this study, we demonstrate that the aptamer can be internalized into pancreatic cancer cells and can thus be used for the targeted delivery of therapeutics. Using the aptamer as a ligand, we established that glycophosphatidylinositol-anchored ALPPL2 is internalized by the cells through clathrin-independent and caveolae-dependent or dynamin-mediated cell-type-dependent pathways. Finally, we show that SQ2 can deliver nucleoside drug 5-fluoro-2'-deoxyuridine specifically to ALPPL2-expressing pancreatic cancer cells, inhibiting cell proliferation.
|
2022-12-24T14:12:19.126Z
|
14,358,110 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ECCTD.2009.5275026",
"MAG": "2161342381",
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},
"license": null,
"status": null,
"url": null
}
|
This paper presents a high-speed low-complexity three-parallel Reed-Solomon (RS) decoder for 6-Gbps mmWave WPAN systems. Three-parallel processing is used to achieve 6-Gbps data throughput and low hardware complexity. Three-way parallelizing for syndrome computation and error correction allow the inputs to be received at very high data rates and the outputs to be delivered at correspondingly high rates with a minimum delay. The proposed three-parallel RS decoder has been implemented 90nm CMOS technology optimized for a 1.2V supply voltage. The implementation result shows that the proposed RS decoder can operates at a clock frequency of 400MHz and has a data throughput 9.6-Gbps. The proposed three-parallel RS decoder architecture has a much higher data processing rate and low hardware complexity, and also can be adapted in the FEC devices for mmWave WPAN systems with a data rate of 6Gbps and beyond.
|
2022-09-12T10:34:03.616Z
|
147,210,159 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/1547688X.2015.1113348",
"MAG": "2323625595",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
ABSTRACT We draw on Engeström’s (2011a) formative intervention approach to bring together mentor teachers and university supervisors to construct a tool for structuring observations and mentoring student teachers. Data include videos and transcripts from seven meetings where participants discussed mentoring and viewed video records of teaching practice to articulate problems and solutions. We examine how video afforded opportunities for participants to precisely describe problems of practice, to develop a shared vision and language of ambitious instruction, and to collectively construct frameworks to guide their work. Findings have implications for design of professional development for teacher educators and programs of teacher preparation.
|
2022-12-30T18:27:44.788Z
|
133,274,853 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.6185/TJIA.V.16.N2.P147P185",
"MAG": "2561325165",
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},
"license": null,
"status": null,
"url": null
}
|
China and India have emerged as powerful growth engines of the world in the twenty-first century, whose durability has been testified by the successful weathering of the Global Financial Crisis since 2008. The main marker has been the presence of a growing middle-class which has generated domestic demand and, thereby, spurred economic growth. Bilateral trade has grown phenomenally in the past one decade, as has cooperation in other areas. Despite problems, they have been trying hard to promote a congenial atmosphere to carry on with their objectives of nation-building through sustainable development. One of their most pressing concerns has been the integration of their far-off peripheral regions politically, economically, culturally and socially with their mainstreams. They have realised that these backward regions, namely Southwest China and Northeast India, share historical ties with not only each other, but also the entire landmass stretching out to Southeast Asia. One of the multilateral initiatives that they have joined to further their stated aims for this sub-region is the Bangladesh, China, India, Myanmar (BCIM) Regional Cooperation Forum. This paper aims to discuss the prospects for sub-regional cooperation between China and India to develop their frontier areas under the auspices of the BCIM Forum.
|
2022-02-09T12:43:35.790Z
|
85,123,423 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1354/vp.44-4-560-a",
"MAG": "2054525043",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This compilation of techniques for non–histology-based methods of phenotyping mutant mice comes from members of the EUMORPHIA consortium. It is an excellent companion to the text What’s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice, by J. Crawley (Wiley-Liss, New York, 2000). Its particular value stems from both its detail and its range of information. Each chapter in the book is dedicated to a particular system: acoustic, ocular, cartilage and bone, metabolic and endocrine, neurologic (including behavior and nociception), cardiovascular, and immune (including host–pathogen interactions, general immunology, and allergy). In addition, this book addresses some issues relevant to clinical chemistries and gene expression profiling. Each chapter is well organized, containing various histories on relevant models for human disease as well as genetic disorders common to that system in specific mouse strains and disease models. Each chapter has detailed descriptions and protocols from the European Mouse Phenotyping Resource for Standardized Screens (EMPReSS), which has more than 150 standard operating procedures for a system-based evaluation of mouse phenotypes (all available online). In general, the book is well written, and figures and illustrations are usually understandable and helpful. Researchers using mutant mice will gain the greatest benefit from this text, as it lays out primary, secondary, and tertiary tests to evaluate sensory and functional modalities, and it gives practical information on a host of techniques, specific protocols, and potential pitfalls. In addition to developing a hierarchical approach to evaluating mutant mice, many chapters also identify emerging techniques, sources of equipment, and valuable references. While favoring the EUMORPHIA consortium Web site and resources, this book also gives additional published and Internet-based sources for those trying to evaluate mutant mice (although some Web addresses seem to have changed or become inactive, while others are not in English). This book will be of most value to researchers working with genetically engineered mice and, to some extent, veterinarians and pathologists working with these researchers.
|
2022-02-10T23:39:36.377Z
|
120,050,875 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1063/1.4745589",
"MAG": "2008972008",
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},
"license": null,
"status": null,
"url": null
}
|
Though the transport properties of chaotic systems are computable from periodic orbits, in practice, such computations are easiest to realize in sufficiently hyperbolic systems dominated by short orbits. Phase spaces exhibiting a mixture of chaos and regularity, however, present a greater challenge, owing to the richer topological dynamics in the vicinity of stable islands and the importance of longer orbits. We demonstrate how, using a sufficiently accurate symbolic dynamics, periodic orbit techniques can compute classical decay rates even in a strongly mixed phase space.
|
2022-09-04T22:26:45.254Z
|