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228,886,943
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1161/CIRC.142.SUPPL_3.13022", "MAG": "3100591964", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Objectives: To identify right heart catheterization (RHC)-assessed hemodynamic parameters of pulmonary circulation that were prognostic predictive of long-term survival in acute coronary syndrome (...
2022-01-27T06:20:14.146Z
143,585,367
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2307/4141093", "MAG": "2019535662", "PubMedCentral": null }, "license": null, "status": null, "url": null }
In a project funded by NEH and Mellon, AATSP and the National Foreign Language Center surveyed 240 randomly-selected higher-education Spanish programs on the availability and the nature of programming for heritage speakers of Spanish. The survey queried perceived need for such programming and challenges to meeting needs of heritage learners. Of the 146 responding programs, 17.8% had SNS programs. Of those reporting a need but no programs, 93% cited insufficient enrollments, followed by insufficient funds and lack of trained faculty. Of those with SNS programs, the largest problems were a lack of program information (65%), of interest (62%), and of effective placement (55%). In classes mixing heritage and foreign language learners, 83% reported heritage students as resources for others; 74%, inconsistencies between home- and classroom-taught Spanish; and 65%, heritage speakers making foreign language learners feel incompetent.
2022-10-22T16:44:27.672Z
23,919,091
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1097/CCM.0b013e31825fd39d", "MAG": "2047974480", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Objectives:Although the majority of sudden cardiac arrests occur in patients with ischemic heart disease, the effect of therapeutic hypothermia on arrhythmia susceptibility during acute global ischemia is not well understood. While both ischemia and severe hypothermia are arrhythmogenic, patients undergoing therapeutic hypothermia do not have an increase in arrhythmias, despite the fact that most sudden cardiac arrest occur in the setting of ischemia. We hypothesized that mild hypothermia induced prior to myocardial ischemia and reperfusion will have a beneficial effect on ischemia-related arrhythmia substrates. Design:We developed a model of global ischemia and reperfusion in the canine wedge preparation to study the transmural electrophysiologic effects of ischemia at different temperatures. Setting:Animal study. Subjects:Male mongrel dogs. Interventions:Canine left ventricle wedge preparations at 1) control (36°C) or 2) mild hypothermia, to simulate temperatures used in therapeutic hypothermia (32°C), were subjected to 15 mins of no-flow ischemia and subsequently reperfused. Measurements and Main Results:Optical action potentials were recorded spanning the transmural wall of left ventricle. Action potential duration for epicardial, mid-myocardial, and epicardial cells was measured. Transmural dispersion of repolarization and conduction velocity were measured at baseline, during ischemia, and during reperfusion. No difference was seen at baseline for conduction velocity or dispersion of repolarization between groups. Conduction velocity decreased from 0.46 ± 0.02 m/sec to 0.23 ± 0.07 m/sec, and dispersion of repolarization increased from 30 ± 5 msecs to 57 ± 4 msecs in the control group at 15 mins of ischemia. Mild hypothermia attenuated both the ischemia-induced conduction velocity slowing (decreasing from 0.44 ± 0.02 m/sec to 0.35 ± 0.03 m/sec; p = .019) and the ischemia-induced increase in dispersion of repolarization (25 ± 3 msecs to 37 ± 7 msecs; p = .037). Epicardial conduction block was observed in six of seven preparations of the control group, but no preparations in the mild hypothermia group developed conduction block (0/6). Conclusions:Mild hypothermia attenuated ischemia-induced increase in dispersion of repolarization, conduction slowing, and block, which are known mechanisms of arrhythmogenesis in ischemia. These data suggest that therapeutic hypothermia may decrease arrhythmogenesis during myocardial ischemia.
2022-12-03T17:48:09.622Z
120,206,016
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/00150197608236709", "MAG": "1970767535", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Some limitations of materials used in the pyroelectric vidicon are briefly discussed. Details of improved lead germanate derivatives are given and the vidicon performance of some oxide materials is assessed.
2022-09-10T12:06:38.125Z
424,411
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2174/157340311795677743", "MAG": "2142412641", "PubMedCentral": "3131713" }, "license": "CCBY", "status": "GREEN", "url": "https://europepmc.org/articles/pmc3131713?pdf=render" }
Introduction: In patients with carotid artery stenosis histological plaque composition is associated with plaque stability and with presenting symptomatology. Preferentially, plaque vulnerability should be taken into account in pre-operative work-up of patients with severe carotid artery stenosis. However, currently no appropriate and conclusive (non-) invasive technique to differentiate between the high and low risk carotid artery plaque in vivo is available. We propose that 7 Tesla human high resolution MRI scanning will visualize carotid plaque characteristics more precisely and will enable correlation of these specific components with cerebral damage. Study objective: The aim of the PlaCD-7T study is 1: to correlate 7T imaging with carotid plaque histology (gold standard); and 2: to correlate plaque characteristics with cerebral damage ((clinically silent) cerebral (micro) infarcts or bleeds) on 7 Tesla high resolution (HR) MRI. Design: We propose a single center prospective study for either symptomatic or asymptomatic patients with haemodynamic significant (70%) stenosis of at least one of the carotid arteries. The Athero-Express (AE) biobank histological analysis will be derived according to standard protocol. Patients included in the AE and our prospective study will undergo a pre-operative 7 Tesla HR-MRI scan of both the head and neck area. Discussion: We hypothesize that the 7 Tesla MRI scanner will allow early identification of high risk carotid plaques being associated with micro infarcted cerebral areas, and will thus be able to identify patients with a high risk of periprocedural stroke, by identification of surrogate measures of increased cardiovascular risk.
2022-09-11T12:01:37.269Z
148,705,111
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.17060/IJODAEP.2017.N1.V2.960", "MAG": "2765395443", "PubMedCentral": null }, "license": null, "status": null, "url": null }
La mayor parte de los ninos y adolescentes diagnosticados como Trastorno por Deficit de Atencion e Hiperactividad (TDAH) o Trastorno del Espectro Autista (TEA) muestran dificultades de aprendizaje. Los resultados obtenidos por diversos estudios muestran el efecto positivo de la Actividad Fisica (AF) en estos escolares. En este trabajo pretendemos conocer el efecto inmediato de la AF sobre el rendimiento academico (RA) y cognitivo (RC). Se consultaron cuatro bases de datos (PubMed, SportDiscus, Web of Science and SCOPUS), limitado las fechas de los estudios a enero 2010 – septiembre 2016. Se emplearon combinaciones de los terminos: “physical fitness”, “attention-deficit hyperactivity disorder”, “Autism spectrum disorder” y “adolescent” “children”. De un total de 260 articulos, se seleccionaron 13, todos de alta calidad. En todos ellos, los participantes eran escolares (6-18 anos) diagnosticados TDAH o TEA. Los trabajos midieron variables de RA y/o RC antes y despues de intervenir con un programa de AF. Las sesiones empleadas en cada estudio son muy diversas, pero todas coinciden en que la actividad realizada fue de caracter aerobico y a una intensidad moderada/moderada-vigorosa. Al finalizar el programa de AF se comprobaron mejoras en las variables dmemoria de trabajo, planificacion, inhibicion y velocidad de procesamiento, frente al grupo control y respecto a las mediciones previas a la intervencion. Por lo tanto, concluimos que los escolares TDAH y TEA con dificultades de aprendizaje que practica AF de forma sistematica mejoran sus niveles de RA y RC.
2022-11-25T01:07:24.288Z
122,949,603
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/03610928008827888", "MAG": "2070134358", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This paper is devoted to the study of che following tsodel:A series-parallel system consists of (k + 1) subsystem C0C1 ,…,Ck, , also called cut sets. Cut sec C1 has ni. com­ponents arranged in parallel, i = 0,1,…,k. Jo two cut sets have a component in comeon. This model was introduced and studied by El-Heweihi, Proschan, and Sethuraiaan (1978) under the assumption that component lifelengths are continuous, indepdent, and identically distributed random variables. They obtained several equivalent expressions for the probability that a specified cut set C0, say, fails first. These expressions aere then used to derive qualitative properties of this probability, such as monotonicity, Schur-concavity, etc. In this paper we obtain extensions of these results, tinder -he same assumptions ve study the probability that a. specified cut set C0say, fails in the rth place, r = l,2,…,k. This probability Is shown to retain most of the interesting qualitative features enjoyed in the special case r = 1. We then assure* th...
2022-12-11T04:52:50.014Z
235,069,506
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1484/J.SEC.5.122986", "MAG": "3138251773", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Tribes and tribal spaces in the ancient and medieval worlds. A thematic dossier prepared by Laïla Nehmé and Jean-Pierre Van Staevel.
2022-12-23T02:10:18.149Z
233,253,603
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.11648/J.IJLS.20200304.18", "MAG": "3121420515", "PubMedCentral": null }, "license": null, "status": null, "url": null }
When the risk of collision exists between a ship underway and an anchored ship, the ship underway should take active measures to avoid the collision as required by the rules, but it doesn’t release the anchored ship’s obligation to take all possible measures to avoid the collision or reduce the consequences of the collision. It is often misunderstood that the anchored ships do not bear the liabilities for collision losses, or only bear a small proportion of the responsibility due to the limitation of their maneuvering ability. However, in practice of maritime trial, lots of anchored ships were decided by the maritime courts to have faults and bear the liabilities for the collision damages because they failed to maintain a proper lookout, detect the presence of the collision risk in time, and issue a warning of the danger to related ships, or failed to notify the master of the own ship to heave up anchor for emergency manoeuvring. This paper, through statistical analysis of a large number of cases related to ship collision cases, analyzes the requirements of laws and regulations on the duty of anchored ships, the common faults and the difficulties and obstacles in taking action by anchored ships to avoid collision, studies a great number of maritime cases, summarizes the lessons learned from those cases, and put forward the reasonable and lawful suggestions and actions by the anchored ships to avoid collision so as to provide advice for shipping companies, ship managers, ship masters and crew members.
2022-01-27T04:05:22.341Z
202,224,057
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.22349/1994-6716-2019-98-2-27-38", "MAG": "2968668754", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The article considers the influence of carbon in the range from 0.008 to 0.18 mass. % at the temperature of complete polymorphic transformation, microstructure and mechanical properties of near-alphatitanium alloy systems Ti–6.2Al–Sn–Zr–(2.19–3.53) Moeq–(0.18–0.28)Si–(0.008–0.18)С. Alloying with carbon is possible due to special titanium sponge or industrial ligatures. Six experimental forgings performed on bimodal microstructured ingots allowed to establish a rational level of carbon. It is shown that carbon alloying at solubility limit (up to 0.08% by weight) increases the heat resistance of the material, while a similar alloying with silicon gives a greater effect. The carbon effect on the strength at room temperature is negligible. Negative effect of carbon on the impact toughness of the alloys is marked. For the selected carbon alloying level at strength of 1165–1180 MPa, the impact viscosity remains at an acceptable level of KCU = 330–381 kJ/m2 . The alloys of the investigated system allow hot deformation in heavy conditions under hammer forging at relatively low temperatures of the two-phase region.
2022-02-08T04:57:31.367Z
238,773,303
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.7546/jgsp-60-2021-1-23", "MAG": "3190355647", "PubMedCentral": null }, "license": null, "status": null, "url": null }
In this paper we study the Gauss map of surfaces in three-dimensional Heisenberg group using the Gans model of the hyperbolic plane. We establish a relationship between the tension fields of the Gauss maps and the mean curvatures of the surfaces in $\mathcal{H}_{3}$.
2022-02-07T20:26:54.407Z
121,389,783
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1143/PTPS.157.160", "MAG": "2060810128", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Transport phenomena of charge density waves and flux line lattices under quenched randomness are investigated based on the three-dimensional driven random-field XY model at zero temperature. We pay special attention to the role of topological defects, vortex loops, and find that loops are bounded in small region and its number density decreases exponentially with the driving force in relatively high velocity regime. That is, the system behaves as in thermal equilibrium state at temperature proportional to the inverse of the driving force.
2022-09-02T05:18:44.754Z
148,199,595
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.15640/ijgws.v3n2a8", "MAG": "2467315527", "PubMedCentral": null }, "license": null, "status": "BRONZE", "url": "http://ijgws.com/journals/ijgws/Vol_3_No_2_December_2015/8.pdf" }
This article presents the issue of housing for Palestinian-Israeli single-mothers, presenting both a gender analysis of their available housing options and the case for their right to adequate housing. A critical analysis from the perspective of gender mainstreaming on these women's rights to adequate housing creates a prism for examining additional spheres of life that relate to them and their children. The paper is based on a study I conducted among Palestinian-Israeli single-mothers, whether divorced, separated or widowed, which examined their situation and status in their families and communities. The data was collected through indepth semi-structured interviews which were analyzed according to the principles of feminist research. The findings indicate that in the absence of government solutions, women are relegated to repressive family arrangements without autonomous spaces for themselves and their children. Their existential and housing difficulties can in extreme cases even put their lives at risk.
2022-12-01T15:24:25.211Z
86,064,345
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1099/00221287-134-10-2659", "MAG": "2153133460", "PubMedCentral": null }, "license": null, "status": "BRONZE", "url": "https://doi.org/10.1099/00221287-134-10-2659" }
Summary: When nickel-depleted cells of Anabaena cylindrica with nitrogenase repressed by growth on ammonia or into late stationary phase) were used to re-initiate nitrogen-fixing growth in fresh nickel-depleted medium a pronounced growth lag was observed. The growth lag was not observed in the presence of NiSO4 (0.68 μM). It was associated with delayed heterocyst differentiation, delayed nitrogenase synthesis and inhibition of pigment synthesis. During the lag a pronounced but transient accumulation of cyanophycin was observed, followed by an accumulation of urea in the growth medium. It is proposed that nickel depletion results in a diversion of ammonia from protein synthesis into cyanophycin, thereby delaying the de novo synthesis of proteins and enzymes required for the synthesis of active nitrogenase.
2022-12-07T16:54:29.617Z
1,845,318
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/TEST.1991.519494", "MAG": "2165789246", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Hardware verifrcation and sequential test generation are aspects of the same problem, namely to prove the equal behavior determined by two circuit descriptions. During test generation, this attempt succeeds for the faulty and fault free circuit if redundancy exists, and during verifrcation it succeeds, if the implementation is correct with regard to its specification. This observation can be used to cross-fertilize both areas, which have been treated separately up to now. In this work, a common formal pamework for hardware verification and sequential test pattern generation is presented, which is based on modeling the circuit behavior with temporal logic. In addition, a new approach to cope with non resetable flipfiops in sequential test generation is proposed, which is not restricted to stuck-at faults. Based on this verification view, it is possible to provide the designer with one tool for checking circuit correctness and generating test patterns. Its first implementation and application is also described.
2022-12-10T09:53:00.359Z
25,517,636
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/146532400539099", "MAG": "2126008414", "PubMedCentral": null }, "license": null, "status": null, "url": null }
BACKGROUND Dendritic cells (DC) are APC that initiate primary T-cell dependent immune responses. They have been shown to be generated from CD34+ cells in BM, placental/umbilical cord blood (CB), and G-CSF mobilized peripheral blood CD34+ cells (PBSC). In recent clinical studies, DC were used as a vaccine for cancer patients and showed induction of their antitumor effects. Cryopreservation of CD34+ cells is important to extend the availability of cellular therapy with DC. However, little is known about the effect of cryopreservation on the functional maturation of DC. METHODS PBSC harvested from lymphoma patients mobilized with G-CSF and undergoing leukapheresis were cryopreserved at -135 degrees C for 3 days. Freshly isolated or cryopreserved PBSC were cultured with GM-CSF/SCF/tumor necrosis factor-alpha (TNF-alpha). After 14 days of culture, DC were harvested, washed, and used for phenotypical and functional analysis. RESULTS Cryopreserved PBSC, as well as freshly-isolated PBSC cultured for 14 days, gave rise to CD1a+ /CD4+ /CD11c+ /CD14low+ /CD25( -)/CD40+ / CD45RO+/CD80+/CD83+/CD86+/HLA-DR+ cells with dendritic morphology. DC derived from cryopreserved PBSC mobilized with G-CSF showed a similar endocytic capacity and chemotactic migratory capacities when compared with DC derived from freshly-isolated G-CSF mobilized PBSC. These DC also exhibited similar capacities in the primary allogeneic T-cell response. DISCUSSION These results indicate that cryopreserved G-CSF mobilized PBSC cultured with GM-CSF/SCF/TNF-alpha gave rise to DC that were morphologically, phenotypically and functionally similar to DC derived from fresh G-CSF mobilized PBSC. The observation indicates the clinical usefulness of cryopreserved CD34+ cells from lymphoma patients.
2022-12-13T00:59:26.956Z
37,165,089
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/15374416.2015.1046177", "MAG": "1898654054", "PubMedCentral": null }, "license": null, "status": "CLOSED", "url": null }
Anxiety disorders are the most common mental health disorder among children and adolescents. We examined 111 treatment outcome studies testing 204 treatment conditions for child and adolescent anxiety published between 1967 and mid-2013. Studies were selected for inclusion in this review using the PracticeWise Evidence-Based Services database. Using guidelines identified by this journal (Southam-Gerow & Prinstein, 2014), studies were included if they were conducted with children and/or adolescents (ages 1–19) with anxiety and/or avoidance problems. In addition to reviewing the strength of the evidence, the review also examined indicators of effectiveness, common practices across treatment families, and mediators and moderators of treatment outcome. Six treatments reached well-established status for child and adolescent anxiety, 8 were identified as probably efficacious, 2 were identified as possibly efficacious, 6 treatments were deemed experimental, and 8 treatments of questionable efficacy emerged. Findings from this review suggest substantial support for cognitive-behavioral therapy (CBT) as an effective and appropriate first-line treatment for youth with anxiety disorders. Several other treatment approaches emerged as probably efficacious that are not primarily CBT based, suggesting that there are alternative evidence-based treatments that practitioners can turn to for children and adolescents who do not respond well to CBT. The review concludes with a discussion of treatments that improve functioning in addition to reducing symptoms, common practices derived from evidence-based treatments, mediators and moderators of treatment outcomes, recommendations for best practice, and suggestions for future research.
2022-12-26T00:16:04.214Z
21,070,712
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3201/eid1611.100100", "MAG": "2127181111", "PubMedCentral": "3294505" }, "license": "CCBY", "status": "GOLD", "url": "https://doi.org/10.3201/eid1611.100100" }
To determine whether rapid emergence of Salmonella enterica serovar Infantis in Israel resulted from an increase in different biotypes or spread of 1 clone, we characterized 87 serovar Infantis isolates on the genotypic and phenotypic levels. The emerging strain comprised 1 genetic clone with a distinct pulsed-field gel electrophoresis profile and a common antimicrobial drug resistance pattern.
2022-12-29T17:14:34.444Z
248,301,605
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3389/fmars.2022.816772", "MAG": null, "PubMedCentral": null }, "license": "CCBY", "status": "GOLD", "url": "https://www.frontiersin.org/articles/10.3389/fmars.2022.816772/pdf" }
The impacts of climate change are expected to have profound effects on the fisheries of the Pacific Ocean, including its tuna fisheries, the largest globally. This study examined the combined effects of climate change on the yellowfin tuna population using the ecosystem model SEAPODYM. Yellowfin tuna fisheries in the Pacific contribute significantly to the economies and food security of Pacific Island Countries and Territories and Oceania. We use an ensemble of earth climate models to project yellowfin populations under a high greenhouse gas emissions (IPCC RCP8.5) scenario, which includes, the combined effects of a warming ocean, increasing acidification and changing ocean chemistry. Our results suggest that the acidification impact will be smaller in comparison to the ocean warming impact, even in the most extreme ensemble member scenario explored, but will have additional influences on yellowfin tuna population dynamics. An eastward shift in the distribution of yellowfin tuna was observed in the projections in the model ensemble in the absence of explicitly accounting for changes in acidification. The extent of this shift did not substantially differ when the three-acidification induced larval mortality scenarios were included in the ensemble; however, acidification was projected to weaken the magnitude of the increase in abundance in the eastern Pacific. Together with intensive fishing, these potential changes are likely to challenge the global fishing industry as well as the economies and food systems of many small Pacific Island Countries and Territories. The modelling framework applied in this study provides a tool for evaluating such effects and informing policy development.
2022-12-30T00:53:44.006Z
144,691,083
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/1755182X.2014.913364", "MAG": "2040672435", "PubMedCentral": null }, "license": null, "status": null, "url": null }
– with its demands for better roads and railroads, highway signs and hotels – was hardly a product of Parisian elites imposing their will on the provinces, but instead reflected the efforts of local chambers of commerce, writers, hoteliers and other literate Bretons themselves. The book also offers a nuanced analysis of the freighted relationship between tourism and the ‘authentic’ or ‘traditional’ in Brittany. The promoters of tourism fretted that genuine mass tourism might threaten Brittany’s perceived distinctiveness (and at the same time undermine their own ability to function as arbiters of tourist value). But Young highlights that these fears were already somewhat beside the point because the objects or practices that constituted Breton ‘heritage’ by the late nineteenth or early twentieth century were hardly pristine relics of enduring religious or regional traditions, but had already been transformed by their placement in entirely novel and modern contexts, from museums that preserved peasant costumes to quasi-religious festivals that included bicycle racing as a means of drawing bigger crowds. Young’s work also raises the idea that the tourist project implicated ordinary Breton men and women in the processes of modernization, but his argument here is weaker than elsewhere in the book. Most of his evidence comes from the accounts of literate outsiders, whether Anglophone tourists or Breton elites; it is understandably more difficult to capture the perspectives of Breton peasants and fishermen themselves on their own ‘traditions’. Enacting Brittany also would have been better-served by its editors, who could have trimmed some of the chapters. The monograph’s thematic organization creates a degree of repetition and chronological murkiness, where it is at points difficult to determine whether the argument concerns the late nineteenth century, the decade before the First World War, or the inter-war period. Finally, the monograph is slightly undermined by repeated typographical inconsistencies. There are at least three different spellings deployed for the island commune and monastery of Mont Saint-Michel (which appears as Mount Saint Michel on page 131, Mount St Michel on page 241 and Mont-St Michel on page 221), and there is some confusion over possessives for the last names of Henri Dorgères (264) and Paul Vidal de la Blache (230). Still, these editing issues by no means take away from Young’s substantial accomplishment in linking a focused regional study to a much broader argument for the centrality of tourism to nation-building in modern France.
2022-07-10T04:27:54.517Z
42,606,266
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1103/PHYSREVA.31.634", "MAG": "2042624049", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The l,m-substate distribution in low-lying Rydberg manifolds (nroughly-equal10) following electron capture H/sup +/+H(1s)..-->..H(n)+H/sup +/ is calculated at high velocities (v>1 a.u.) in the continuum-distorted-wave (CDW) approximation. The standard CDW approximation is modified to account for final-state Stark mixing of the Rydberg manifold in the exit channel using the post-collision-interaction model. The influence of multiple-scattering contributions is analyzed and comparison is made with sigma/sub l/m predicted by the Born approximation. We find that the double-scattering contribution, closely connected with the classical Thomas process, becomes visible in the CDW approximation at surprisingly low nonasymptotic velocities.
2022-09-12T06:08:32.483Z
6,668,091
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1542/peds.91.1.193", "MAG": "1595279996", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Most children with special needs are more like normally developing children than they are different from them. They share the same zest for discovery, love for stories and music, and delight in dressing in adult clothes. They, too, need to learn to run and play, solve problems, have conversations with friends, and attend to their personal needs. Finding an opening in a child care center can be a long, frustrating experience for families, particularly when employment is essential to cover basic needs. The problem of locating a satisfactory place increases tenfold when children have special needs. After learning that a prospective child has special needs, a child care center director will turn his or her attention to the impact the child's needs might have on center operations. The director fails to recall the commonalities these children share with other enrolled children. Multiple, abortive efforts to locate placement exacerbate family stress. In desperation, parents may drop the criteria they had believed to be important in selecting placement, feeling relieved and grateful that, at last, they can go to work. To address this problem, we will first examine the characteristics of young children with special needs and indicate the prevalence of the problem. The traditional delivery models for early intervention and for child care will be reviewed, and barriers that inhibit provision for children with special needs in child care facilities will be noted. Some current models and practices that are effective will be reviewed. Finally, recommendations will be made for policy makers and providers of services.
2022-09-13T19:41:43.288Z
235,525,548
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1002/er.6819", "MAG": "3157348268", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This paper deals with optimal multi‐stage power management and control coordinated with load shedding in interconnected microgrid (MG) with various renewable energy sources (RESs), namely: wind turbine, photovoltaic generator and concentrated solar power generator. Hybrid energy storage systems including electrical vehicles, fuel cells, redox flow batteries and superconducting magnetic energy storage have been introduced to improve the overall MG frequency dynamic performances in case of renewable energy integration and load disturbances. To improve the interconnected MG tie‐lines power control, flexible alternating current transmission systems are added. For an optimal and robust solution, an artificial intelligence strategy is proposed, combining a load frequency control‐based cascade Fuzzy‐proportional‐integral‐derivative controller with filter (PIDN). In doing so, a recently meta‐heuristic algorithm that mimics the social behavior of elephants in nature, named Elephant Herding Optimization, has been employed to optimize the Fuzzy‐PIDN controller gains. To show the effectiveness and superiority of the proposed control strategy, various scenarios are carried out. A comparative study in view of a settling time and peak over/undershoot has been performed. The obtained results demonstrate that the proposed control strategy gives good performances for MG power management and control under RESs integration and load disturbances scenarios.
2022-10-21T16:15:49.436Z
71,719,430
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.9734/BJMMR/2015/15789", "MAG": "2036744050", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Aims: The association between intraoperative respiratory events (IRE) and post-anesthetic care unit respiratory events (PARE) in children as well as the risk factors for PARE have not been described. The objectives of this study were to describe the association between IRE and PARE and to identify the risk factors of PARE in children at a tertiary care hospital in southern Thailand. Methodology: A historical cohort study based on the surveillance anesthetic database and chart review of children who received surgery at Songklanagarind Hospital during January 2005 to December 2011 was conducted. Demographic, surgery and anesthesia-related data were Original Research Article Oofuvong et al.; BJMMR, 6(11): 1101-1112, 2015; Article no.BJMMR.2015.288 1102 collected. The association between IRE and PARE and other potential risk factors were analyzed using cross tabulation. Multivariate logistic regression was employed to identify independent predictors for PARE, indicated by adjusted odds ratios (aOR) and their 95% confidence intervals (CI). Results: Overall, perioperative respiratory event (PRE) occurred in 531 out of 14153 children (315 IRE, 348 PARE). The association between PARE and IRE was strong, with adjusted odds ratios ranging from 3.1 (laryngospasm) to 18.5 (desaturation). Anesthesia-related risk factors for PARE were ASA classification 3 (aOR=3.1, 95%CI=1.9-5.0), jet ventilation (aOR=3.4, 95%CI=1.6-7.1), intubation with succinylcholine vs non-depolarizing muscle relaxant (aOR=1.9, 95%CI=1.4-2.5), use of intraoperative morphine vs fentanyl (aOR=2.4, 95%CI=1.7-3.3) and duration of anesthesia ≥ 3 hours (aOR=3.2, 95%CI=2.1-4.9). Conclusion: The magnitude of association between IRE and PARE was high. Increased vigilance and close monitoring by anesthesia personnel in high risk children and high risk surgery may prevent IRE and therefore also PARE, so that overall PRE can be reduced. Preventable risk factors for PARE such as using succinylcholine and morphine can be managed under discretion of the anesthesiologist.
2022-06-13T02:08:03.959Z
94,993,763
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1021/OM070110F", "MAG": "1991398726", "PubMedCentral": null }, "license": null, "status": null, "url": null }
A mechanism for the regioselective silaboration of terminal allene by a palladium catalyst has been studied theoretically. The overall reaction scheme has been examined in particular to determine t...
2022-09-17T14:20:29.365Z
139,169,916
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1021/ACSANM.8B01677", "MAG": "2909868576", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Semiconductor nanowires are a class of materials that recently have gained increasing interest in solar-cell applications and light-emitting devices. Finding reproducible processing conditions is fundamental for their future mass production. In this work, the stability of individual epitaxial GaAs nanowires (NWs) under molecular beam epitaxy (MBE) processing conditions is studied by means of a time-resolved in situ micro X-ray diffraction (μXRD) method and scanning electron microscopy. Our proposed μXRD method is a nondestructive characterization technique where individual nanoobjects of different dimensions, crystal orientations, and structures are detectable under MBE processing conditions. NWs were grown by self-catalyzed MBE onto prepatterned Si(111) substrate. When exposed to MBE processing conditions at 610 °C without supply of a source material, or with only an arsenic (As) supply, we observe evaporation from the facets with no indication of gallium (Ga) droplet formation. Furthermore, the NWs, whi...
2022-12-15T08:07:18.359Z
154,254,130
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/02692171.2012.752445", "MAG": "2004549862", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The eruption of the Arab Spring in Tunisia and Egypt was ensued by deterioration in FDI inflows. Whether a new Middle East free of corruption accompanying previous dictatorships will offset the negative ramifications of the uprisings and enhance FDI in the long run remains debatable. Since the evidence on the causal relationship between corruption and FDI is inconclusive, this study attempts to take another step. The paper investigates the link between corruption and FDI flows to the Middle East and North Africa (MENA) and assesses whether or not corruption has more importance than other FDI determinants. By employing several panel settings with various econometric specifications on 21 MENA countries over the period 2003 to 2009, it is demonstrated that FDI varies positively with corruption. Additionally, FDI in MENA was found to vary positively with per capita income, openness, freedom and security of investments and negatively with the tax and homicide rates. Since corruption was not found to hinder FDI inflows, treating corruption should be based on sound legal procedures that infringe neither on the rights, freedom and security of FDI nor on the degree of openness and freedom of the economy, which are the real stimulants of FDI in MENA.
2022-12-21T17:02:25.330Z
121,868,713
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1063/1.4902576", "MAG": "2038462228", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Several years ago, Carlo Cercignani and one of the authors in a paper (C. Cercignani, 2991) performed a mathe-matical analysis of the corrections to the Rankine-Hugoniot conditions due to the curvature of a shock front, using singular perturbation methods in order to “connect” the solutions to the the Boltzmann equation inside and outside the shock layer. It turned out that these corrections can be obtained at leading order by integrating appropriately the Boltzmann shock profile for a planar (one-dimensional in space) shock wave. However, they are entirely due to the spatially asymmetry of the shock, and they vanish if the shock is described using a simple bi-modal ansatz like the well-know Mott-Smith model. In the present work we extend and simplify the previous results, and then use a recently-developed deterministic (spectral) Boltzmann solver for a gas of hard-spheres in order to obtain accurate numerical values for the curvature corrections.
2022-02-09T19:45:37.368Z
240,291,755
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2139/ssrn.3977771", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
Uncertainty surrounding if the U.S. will implement a federal climate policy introduces risk into the decision to invest in long-lived capital assets, particularly those designed to use, or to replace fossil fuel. We develop a dynamic, general equilibrium model to quantify the macroeconomic impacts of this climate policy transition risk. The model incorporates beliefs over the likelihood that the government adopts a climate policy causing the economy to dynamically transition to a lower carbon steady state. We find that climate policy transition risk decreases carbon emissions today by causing investment to become relatively cleaner and output to fall. This result counters the Green Paradox, which argues that climate policy risk raises emissions today by increasing incentives to extract fossil fuel, expanding its supply. Even allowing for the supply-side response, we find the demand-side response dominates, and the net effect of climate policy transition risk is still to reduce emissions today. The views expressed in this paper are our own and do not reflect the views of the Federal Reserve System or its staff. This paper was previously circulated under the title “The Macro Effects of Climate Policy Uncertainty.” For helpful comments we thank Sylvain Leduc and Derek Lemoine, as well as seminar and conference participants at SED, the San Francisco Fed Conference on Climate Change, the Federal Reserve Energy System Meeting, Midwest Macro, ASSAs, Berkeley Climate Economics Workshop, UCSB, Harvard, and Universidad del Rosario, and four anonymous referees. All potential errors are our own.
2022-05-22T09:40:30.642Z
250,073,086
{ "externalids": { "ACL": null, "ArXiv": "2206.12681", "DOI": "10.48550/arXiv.2206.12681", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
Convolutional neural network (CNN) approaches available in the current litera-ture are designed to work primarily with low-resolution images. When applied on very large images, challenges related to GPU memory, smaller receptive field than needed for semantic correspondence and the need to incorporate multi-scale features arise. The resolution of input images can be reduced, however, with significant loss of critical information. Based on the outlined issues, we introduce a novel research problem of training CNN models for very large images, and present ‘UltraMNIST dataset’, a simple yet representative benchmark dataset for this task. UltraMNIST has been designed using the popular MNIST digits with additional levels of complexity added to replicate well the challenges of real-world problems. We present two variants of the problem: ‘UltraMNIST classification’ and ‘Budget-aware UltraMNIST classification’. The standard UltraMNIST classification benchmark is intended to facilitate the development of novel CNN training methods that make the effective use of the best available GPU resources. The budget-aware variant is intended to promote development of methods that work under constrained GPU memory. For the development of competitive solutions, we present several baseline models for the standard benchmark and its budget-aware variant. We study the effect of reducing resolution on the performance and present results for baseline models involving pretrained backbones from among the popular state-of-the-art models. Finally, with the presented benchmark dataset and the baselines, we hope to pave the ground for a new generation of CNN methods suitable for handling large images in an efficient and resource-light manner.
2022-07-05T13:43:25.827Z
36,824,294
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1523/JNEUROSCI.4052-14.2014", "MAG": "2090295278", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Spinal cord injury (SCI) in the mammalian CNS results in the formation of a glial scar around the lesion site ([Fig. 1][1] A ). The scar limits axon regeneration but it also serves a protective role by sequestering inflammatory cells to the lesion center, reducing tissue damage ([Herrmann et al.,
2022-07-13T03:17:29.129Z
16,378,326
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/ISPA.2009.5297641", "MAG": "2150788460", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The objective of this paper is to evaluate performance of the level set approach applied to segmentation and tracking of noisy 3D images of computer-simulated blood-vessel phantoms and artificial vascular trees. Of particular interest was the segmentation of thin vessels, with diameter smaller that voxel size. Flood fill technique was also explored, for comparison. Quantitative measures of segmentation accuracy were used for the methods evaluation. It was demonstrated, that the level set method provides good segmentation results even for noisy images. This promising result encourages its future application for vascularity modeling based on MR images.
2022-03-06T04:47:41.074Z
231,754,933
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1094/PHYTO-11-20-0495-R", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
Phytopathogenic Rathayibacter species are unique bacterial plant pathogens as they are obligately vectored by plant parasitic Anguinid nematodes to the developing seedheads of forage grasses and cereals. This understudied group of plant-associated Actinomycetes includes the neurotoxigenic plant pathogen, R. toxicus, which causes annual ryegrass toxicity in grazing livestock. Rathayibacter toxicus is currently endemic to Australia and is listed as a plant pathogen select agent by the U.S. Department of Agriculture - Animal and Plant Health Inspection Service. The complex Rathayibacter disease cycle requires intimate interactions with the nematode vector and plant hosts, which warrants an increased understanding of the secretory and surface-associated proteins that mediate these diverse eukaryotic interactions. Here we present the first comparative secretome analysis for this complex, nematode-vectored Rathayibacter genera that compares the three agronomically-damaging toxigenic and atoxigenic Rathayibacter species, R. toxicus, R. iranicus, and R. tritici. The exoproteomic comparison identified 1,423 unique proteins between the three species using LC-MS/MS, leading to the identification of putative pathogenicity-related proteins and proteins that may mediate nematode attachment. Of the uniquely identified proteins, 94 homologous proteins were conserved between the three Rathayibacter exoproteomes and comprised between 43.4 - 58.6% of total protein abundance. Comparative analyses revealed both conserved and uniquely expressed extracellular proteins, which, interestingly, had more similarities to extracellular proteins commonly associated with bacterial animal pathogens than classical plant pathogens. This comparative exoproteome analysis will facilitate the characterization of proteins essential for vector attachment and host colonization and assist in the development of serological diagnostic assays.
2022-10-07T00:27:14.178Z
247,857,234
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1002/ece3.8998", "MAG": null, "PubMedCentral": "9203590" }, "license": null, "status": "GREEN", "url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203590" }
Estimating the prevalence or the absolute probability of presence of a species from presence-background data has become a controversial topic in species distribution modelling. In this paper we propose a new method by combining both statistics and machine learning algorithms that helps overcome some of the known existing problems. We have also revisited the popular but highly controversial Lele and Keim (LK) method by evaluating its performance and assessing the RSPF condition it relies on. Simulations show that the LK method with unfounded model assumptions would render fragile estimation/prediction of the desired probabilities. Rather we propose the local knowledge condition, which relaxes the pre-determined population prevalence condition that has so often been used in much of the existing literature. Simulations demonstrate the performance of the CLK method utilising the local knowledge assumption to successfully estimate the probability of presence. The local knowledge extends the local certainty or the prototypical presence location assumption, and has significant implications for demonstrating the necessary condition for identifying absolute (rather than relative) probability of presence without absence data in species distribution modelling.
2022-11-04T01:00:30.666Z
244,668,807
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1117/12.2604199", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
An all-fiber system based on the principle of optical waveguide self-imaging for coherent beam combination (CBC) system is designed. A square fiber is used as the beam combination device for all-fiber CBC system. The self-imaging characteristics of the square fiber are studied. The self-imaging effect of the square fiber is verified by theoretical simulation and experiment. The square fiber has good self-imaging characteristics and is suitable for CBC using its self-imaging characteristics.
2022-12-11T01:01:08.431Z
153,535,798
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1111/j.1475-4932.2011.00781.x", "MAG": "1574639382", "PubMedCentral": null }, "license": null, "status": null, "url": null }
In the US academic literature, it is now widely accepted that it is difficult to generate a more accurate forecast of inflation than a simple autoregressive model, following Atkeson and Ohanian's seminal work. In central banks, however, the conventional view that inflation is ultimately determined by excess demand in the economy is still widely accepted, and research into activity‐based models has continued. We add to this research by examining a range of activity‐based models, with the aim being to determine whether any of these can outperform the autoregressive benchmark, and if so, which performs best. Our results show that an expectations‐augmented, unemployment‐based Phillips Curve can produce significantly superior forecasts of Australian trimmed mean inflation to both the autoregressive benchmark and others at a range of forecast horizons, while mark‐up type models also produce superior results at longer horizons. This outperformance is shown to come from the period in which inflation rose to relatively high rates. These results do not, however, translate to headline consumer price index inflation, suggesting that inflation in the items that are ‘trimmed’ largely reflects ‘noise’, as opposed to any signal of trend inflation.
2022-12-21T04:25:41.954Z
245,965,839
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.32460/ishmu-2021-9-0026", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
Статья посвящена проблеме формирования сословий Российского государства в трудах С. В. Юшкова. Продуцируемые концепции русской сословности восходят к европейской традиции, понятия и категории которой не всегда валидны по отношению к отечественному состоянию. Особый контекст несет в себе воссоздание сословности в период развития советской власти. С. В. Юшков на протяжении 1920-1950-х гг. редактировал сословную концепцию, «подстраиваясь» под идеологические особенности советского государства.
2022-01-22T03:23:35.489Z
36,298,194
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1002/ijc.21161", "MAG": "2026873477", "PubMedCentral": null }, "license": null, "status": "BRONZE", "url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/ijc.21161" }
Dear Sir, In the 21 October 2004 issue of the International Journal of Cancer, Rollison and colleagues from 2 laboratories, the Laboratory of Molecular Medicine and Neuroscience, NINDS (LMMN) and the Johns Hopkins Bloomberg School of Public Health (JHU), published a study on the presence of human polyomaviruses BKV, JCV and simian virus 40 (SV40) in a series of brain tumors. In their effort, a total of 9 of 225 samples of brain tumor tissue were found positive for one of the polyomaviruses by one laboratory (LMMN), but the other laboratory (JHU) reported all 9 of these samples as negative. JHU detected polyomavirus in only 1 of 165 samples, a finding that was not reproduced by their collaborators at LMMN. The lack of reproducibility between 2 laboratories evaluating the same set of clinical samples raises several important issues that are both technical as well as conceptual in nature, particularly in terms of sensitivity as well as specificity of the methods that were employed. Several aspects of the methodologies used by the authors should be considered when interpreting their results. In LMMN, the DNA extraction step yielded highly variable results and only 5 ml of template was used regardless of concentration, even if samples were negative. Furthermore, no information was provided on the sensitivity of either the PCR or the Southern blot. Of note, the Southern blot was performed with random primed full-length probes, rather than oligonucleotide probes specific for the target amplicon. The authors indicate that 1.0 ng of JCV and BKV and 0.1 ng of SV40 plasmid were used on the blots as controls, which would be equivalent to 10,000 and 1,000 copies, respectively. Under these conditions, it is likely that the sensitivity of the Southern blot remained off by several orders of magnitude. The JHU laboratory did not seem to have any difficulty in extracting the DNA, and 150 ng of template was used in each reaction. Using real-time quantitative PCR, JCV and BKV were co-amplified using the same primer pair in one reaction, and the 2 were distinguished by melting temperatures of 82 C and 83 C using SYBR Green. It should be noted that quantitative PCR of paraffin-embedded tumor specimens is not well established and assays at present may not be as sensitive as conventional PCR. Nevertheless, positive PCR samples were verified by hybridization using biotinylated oligonucleotide probes, which, as acknowledged by the authors, may not be as sensitive a method as radiolabeling. The authors reported a sensitivity of 10 copies for their assay, although how this number was reached is unclear. The detection of positive controls is also a concern. Whereas LMMN did not report the sensitivity or specificity of their assay, JHU indicated that the positive JCV mouse tumor controls only contained 1.7 and 495.5 copies, which are quite low, especially given that the sensitivity of the assay is reported as 10 copies. In fact, the only human tumor found positive by this laboratory was a medulloblastoma where 0.12 was reported as the copy number for SV40. Copy numbers for PML tissue and the hamster SV40 model were exponentially higher, as one would expect in samples with replicating virus (PML) or injection of large viral inoculum (hamster). No positive controls for BKV were used in this study. The presence of the human polyomaviruses JCV, BKV and simian virus 40 (SV40) in human tumors has been investigated by many groups by PCR analysis with a wide range of conclusions. Care must be taken to ensure that the most sensitive and reproducible methods are utilized and that all appropriate controls are performed to rule out false positives. It is particularly important that negative data are obtained using robust and reproducible methods because such findings can be misleading. Variability in laboratory techniques can lead to differences in sensitivity and/or specificity, which could account for the discord in published results. It should be noted that preservation of paraffin-embedded archived tissue may be one significant source of variability that is difficult to overcome. We wish to extend an open invitation to work with any individuals who may experience difficulty in amplifying human polyomaviruses from their samples and are willing to share reagents, protocols, and expertise to establish the most appropriate methodologies for such studies. We encourage multicenter studies that share blinded and coded samples similar to the format of this study, but such studies should attempt to standardize methods or utilize assays with comparable levels of sensitivity and specificity. It is unfortunate that the present study using large sets of well-characterized tissues did not include laboratories who have routinely published results where polyomaviruses have been successfully and reproducibly detected by complementary techniques. Despite the inconsistencies in the data from LMMN and JHU, which the authors acknowledge may be due to differences in assay sensitivity, they conclude that polyomaviruses may be present at low frequencies and at low copy numbers. Although broad surveys of tumor tissue are important, we suggest that the discussion should move beyond PCR studies, which do not appear to reach consensus but merely add more discordant results to the debate. The authors should acknowledge other methodologies that have detected polyomaviruses in human CNS and non-CNS tumors. For example, to rule out latently infected B cells as the source of polyomavirus, the use of laser capture microdissection (LCM) combined with PCR techniques has demonstrated the presence of polyomavirus sequences specifically within tumor cells. Most notably, a number of groups have reported the unambiguous detection of JCV and SV40 Tantigen in the nuclei of neoplastic cells, as well as the JCV late auxiliary agnoprotein in perinuclear regions, findings that could not result from any type of laboratory contamination. Consistent with these findings, viral capsid proteins have not been detected, suggesting that the virus is nonreplicating. Techniques such as LCM and immunohistochemistry should be used in parallel for validation of PCR amplification. The detection of viral proteins with known transforming capabilities should not be overlooked. T-antigen and agnoprotein are capable of altering a number of cellular signaling pathways
2022-03-07T10:59:50.617Z
154,023,693
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1017/S0009838800031761", "MAG": "2003919919", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The above passage, from Maternus' first speech, poses a number of rather intricate textual problems. J. F. Gronovius rightly divined that the meaningless vaticiniireferred to a person whose evil power Maternus had broken. Who else but Vatinius, Nero's notorious jester? To read Vatiniifor vaticiniiis intrinsically attractive, and in default of a better alternative has found almost universal approval. The contextual implications of this acclaimed conjecture have not, however, always been appreciated. It is with these that the present paper is concerned. Discussing (I) the conjecture imperante Nerone(L. Miiller), and (II) the interpretation of J. Stroux, it will attempt in the final section (III) to relate the Vatinius incident to its original political and ideological context.
2022-09-12T10:24:28.650Z
234,762,860
{ "externalids": { "ACL": null, "ArXiv": "2105.08608", "DOI": "10.1137/21m1442383", "MAG": "3161221583", "PubMedCentral": null }, "license": null, "status": "GREEN", "url": "http://arxiv.org/pdf/2105.08608" }
Let $n$ be a sufficiently large integer with $n\equiv 0\pmod 4$ and let $F_i \subseteq{[n]\choose 4}$ where $i\in [n/4]$. We show that if each vertex of $F_i$ is contained in more than ${n-1\choose 3}-{3n/4\choose 3}$ edges, then $\{F_1, \ldots ,F_{n/4}\}$ admits a rainbow matching, i.e., a set of $n/4$ edges consisting of one edge from each $F_i$. This generalizes a deep result of Khan on perfect matchings in 4-uniform hypergraphs.
2022-11-11T10:38:29.164Z
63,755,503
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1145/1882291", "MAG": "2438388874", "PubMedCentral": null }, "license": null, "status": null, "url": null }
It is my distinct pleasure to also welcome you to the Eighteenth ACM SIGSOFT International Symposium on the Foundations of Software Engineering (FSE-18). We have assembled a highquality technical program that I hope will leave many of you inspired to build upon the results presented to further the state-of-the-art in our field. This year, FSE received 170 submissions, one of which was withdrawn by the authors shortly before the reviewing period commenced. Each of the remaining papers was reviewed by three members of the program committee, with a subset of 74 papers discussed in detail at the program committee meeting that was held in Cape Town, South Africa, after ICSE 2010. Through one-anda- half days of careful deliberations, 34 papers were selected for presentation at the conference and publication in the conference proceedings. Unfortunately, one of these papers was later found to exhibit self-plagiarism, as a result of which the program consists of 33 high-quality papers for an acceptance rate of 20%. I am particularly excited about the breadth of topics covered by the submissions and, indeed, the papers that were ultimately selected for inclusion in the conference. The conference has sessions on distributed systems, concurrency, code similarities, empirical studies of systems, empirical studies of people, verification, replay, web services, testing, dependencies, and analysis, as well as one miscellaneous session that groups papers on combined hardware and software instrumentation to classify program executions, synthesis of life behavior models, and locating need-to-translate constant strings in web applications. This breadth is representative of the diverse interests of our community, and shows how FSE serves as a home for all of this work. I deeply appreciate the many hours that each of the members of the volunteer program committee spent reading the submissions, providing detailed feedback in the reviews, discussing the papers at the program committee meeting, and dealing with various other aspects concerning the program. It was particularly heartening to witness a very positive program committee meeting, with a desire to admit papers rather than to reject them. On a number of papers, this attitude made a difference, and the program only benefitted.
2022-12-10T03:44:06.788Z
204,755,107
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1159/000503343", "MAG": "2980822000", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Background: Studies have highlighted 2 different groups of cocaine users (CUs): “socially integrated” (stable living conditions, regular employment, use cocaine alone or in combination with other psychoactive substances) and “socially marginalized” (socioeconomic and health problems, former or current heroin users, many injecting cocaine). These differences are also found in the elevated mortality risk for CUs, higher among subjects with cocaine and heroin use. This study targeted residents in Northern Italy who turned to a public treatment center for drug addiction following problems caused by primary cocaine use between 1982 and 2016. Objectives: To estimate mortality risk for subjects who have never used heroin (CUs) compared to that of subjects who have used heroin (HCUs). Method: Retrospective cohort study. We selected 1,993 subjects; 18,015 Person Years (PY). Results: Over time, the quota of subjects injecting cocaine and using heroin decreased, while patients not using heroin increased. Both new patients and crude mortality rates (CMR) decreased during the years 2009–2012 and increased in the following period. CMRs were 5.55 per 1,000 PY, higher for HCUs, men and subjects aged over 44 years. Standardized mortality rates were 3.49, higher for women, injecting cocaine and HCUS. Among CUs, most of the deaths were from injury excluding drug related and tumors; among HCUs, from drug-related causes and diseases of the cardiovascular system. Conclusion: The study results show a change in the characteristics of SERD clients being treated for primary cocaine use, which are reflected both in mortality risk and causes of death. After a long period of a decrease, mortality risk increased in the period after the economic recession. Aspects concerning the effects of the economic recession on the problematic consumption of cocaine and on the risk of death are discussed.
2022-12-19T15:29:35.153Z
245,913,437
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1148/ryai.210059", "MAG": null, "PubMedCentral": null }, "license": null, "status": "GREEN", "url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8980882" }
Artificial intelligence (AI)-based image enhancement has the potential to reduce scan times while improving signal-to-noise ratio (SNR) and maintaining spatial resolution. This study prospectively evaluated AI-based image enhancement in 32 consecutive patients undergoing clinical brain MRI. Standard-of-care (SOC) three-dimensional (3D) T1 precontrast, 3D T2 fluid-attenuated inversion recovery, and 3D T1 postcontrast sequences were performed along with 45% faster versions of these sequences using half the number of phase-encoding steps. Images from the faster sequences were processed by a Food and Drug Administration-cleared AI-based image enhancement software for resolution enhancement. Four board-certified neuroradiologists scored the SOC and AI-enhanced image series independently on a five-point Likert scale for image SNR, anatomic conspicuity, overall image quality, imaging artifacts, and diagnostic confidence. While interrater κ was low to fair, the AI-enhanced scans were noninferior for all metrics and actually demonstrated a qualitative SNR improvement. Quantitative analyses showed that the AI software restored the high spatial resolution of small structures, such as the septum pellucidum. In conclusion, AI-based software can achieve noninferior image quality for 3D brain MRI sequences with a 45% scan time reduction, potentially improving the patient experience and scanner efficiency without sacrificing diagnostic quality. Keywords: MR Imaging, CNS, Brain/Brain Stem, Reconstruction Algorithms © RSNA, 2022.
2022-12-18T08:38:38.540Z
97,435,296
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1002/NADC.20000480236", "MAG": "2086631184", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Im Jahre 2000 feiern zahlreiche Kolleginnen und Kollegen das goldene Jubilaum ihrer GDCh–Mitgliedschaft und damit 50 Jahre fruchtbarer und erfolgreicher Zusammenarbeit. Unseren treuen und langjahrigen Mitgliedern danken wir, dass sie den Weg ins neue Millennium gemeinsam mit uns beschritten haben. Bleiben Sie noch recht lange aktiv an unserer Seite! Unsere Gruse und Gluckwunsche gelten
2022-02-10T13:26:07.867Z
72,137,364
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1001/ARCHINTE.1983.00350120144041", "MAG": "2039271478", "PubMedCentral": null }, "license": null, "status": null, "url": null }
To the Editor. —In the AprilArchives(1983;143:753-755), Sacks et al quantitated the performance of randomized control trials (RCTs) and the historical control trials (HCTs) in a format used for the evaluation of tests, and reported that the sensitivity and specificity values were 0.90 and 0.11 for HCTs and 0.12 and 0.88 for RCTs, respectively. The authors considered that the sensitivity and specificity estimates "fell in narrow, nonoverlapping ranges and were quite similar no matter which therapies were assumed effective." Apparently, based on their findings, the authors thought that well-designed RCTs are better for determining the efficacy of new therapies. A nonbiased analysis of the data reported is made possible by using the receiver operating characteristics curves defined by the sensitivity and specificity pairs mentioned. The receiver operating characteristic analysis allows for the transformation of each pair into one value, the discrimination index (d I ). 1,2 The greater d I
2022-02-11T10:08:51.579Z
144,800,424
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1353/tlj.2007.0022", "MAG": "2063273842", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The traditional conception of a contract is that of a legally binding agreement between two private parties who have voluntarily promised something to each other. Often, however, contracts involve third parties in some way. In the British common law tradition, the doctrine of privity of contract addresses third parties’ relationships with contracts to which they are not a party. Succinctly put the doctrine states that contracts can confer rights or impose obligations only on parties to the contract. Problematic situations arise where a contract between two parties purports to confer a benefit on a third party. In these situations, an element of the doctrine of privity that I will term the third-party beneficiary rule expressly denies these third parties any legal rights. In the case law, two factual scenarios have typically arisen. First, third parties might be entitled to money, services, or goods under a contract. A simple example would be that A agrees to purchase a new laptop computer from B and instructs B to deliver it to C, A’s daughter who is attending university in another province. If B does not provide the laptop, then, under the third-party beneficiary rule, C, as a third party, has no right to sue B. Furthermore, A may also lack viable legal recourse against B. A may have lost nothing due to B’s failure to provide the laptop to C; if he sued B, therefore, A might be entitled only to nominal damages. In this scenario, C would wish to assert an affirmative right of action in the contract between A and B. Second, employees or subcontractors, who are deemed to be third parties for the purposes of the rule, might be entitled to a limitation of
2022-03-15T20:37:21.997Z
244,084,200
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.5296/jei.v7i2.19032", "MAG": null, "PubMedCentral": null }, "license": "CCBY", "status": "HYBRID", "url": "https://www.macrothink.org/journal/index.php/jei/article/download/19032/14911" }
In this study, the effects of 8-week swimming training applied to men aged 20-25 on sodium, potassium, magnesium, calcium, unsaturated iron binding capacity (UIBC), iron, CRP, creatinine, bilirubin, albumin parameters were investigated. Ten men with a mean age of 23.07±1.76 years participated in the study. A swimming training program was applied to the participants for 10 weeks/3 days. All tests and measurements were performed before starting the 8-week training program and after completing the 8-week program. The data obtained from the study were analyzed using the SPSS 15.0 package program. The normality distribution of the data was made using the shapiro-wilk test. Participants’ pre-post test measurements were analyzed with the Wilcoxon signed-rank test. According to the results of the data, there was a statistically significant difference between pre-post test data for body weight (BW), sodium, magnesium, creatinine, albumin and bilirubin (p < 0.05). As a result, it can be said that the changes in the minerals and some biochemical parameters necessary for the body with the training programs applied regularly can affect the performance.
2022-08-09T17:12:38.259Z
36,654,459
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2987/11-6164.1", "MAG": "2136583634", "PubMedCentral": null }, "license": null, "status": "GREEN", "url": "https://europepmc.org/articles/pmc3331716?pdf=render" }
Abstract Female Aedes albopictus, F2–F3 descendents from individuals collected as immatures at 6 geographic sites in the USA during 2008, exposed to short daylengths (10 h of light and 14 h of darkness at 21°C) laid eggs in diapause, whose frequency depended upon population origin. Diapause responses in northern Florida and Illinois were strong, as had been reported approximately 10 years earlier for Ae. albopictus from these regions. For southern Florida, the diapause response was polymorphic, and its mean incidence decreased at 2 of 3 collection sites compared to 10 years earlier. Exposure in the field for 2- to 4-wk intervals in Vero Beach (lat 27°35′N) during January 2009 revealed that eggs laid by short-day females had significantly higher survivorship, even though <50% were estimated, from laboratory results, to be in diapause. Enhanced desiccation resistance may select for retention of diapause in southern Florida.
2022-09-05T11:34:20.865Z
129,451,293
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1111/j.1751-3928.1998.tb00005.x", "MAG": "2004254613", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Abstract: The Ashele Cu‐Zn deposit is a recently discovered volcanogenic massive sulfide deposit in Xinjiang, Northwestern China. It is the largest Cu‐Zn deposit in this type of deposits in China, which were formed in the early period of later Palaeozoic Era. This deposit is hosted within a suit of bimodal submarine volcanic rocks of the Ashele Formation of Lower‐Middle Devonian System formed in an environment of paleocontinental margin rift setting. Lensoid orebodies occur between spilitic rocks developed at footwall and quartz‐keratophyric tuff at hanging wall. Zonation of metal elements in the Ashele mine is one of typical volcanic‐related exhalative Cu‐Zn sulfide deposits in the world. Black ores enriched in Pb, Zn and Ag occurs on the top of the No. 1 orebody in the Ashele deposit, yellow ores enriched in Cu in the middle part, and the chalcopyritization stringer below the massive sulfide ores. Zonation of ore‐structure in the No. 1 orebody is also apparent and corresponds to the zoning of elements, i. e. lamellar and/or banded sulfide‐sulfate ores on the top, massive sulfide ores in the middle, and stockwork veinlets associated with altered breccia pipe on the bottom. Four epochs of mineralization in the Ashele deposit has been recognized. The first period of syngenetic‐exhalative deposition of sulfides is the main epoch of mineralization, and the ores deposited subsequently subjected to thermo‐metamorphism at the second epoch, superimposed by hydrothermal mineralization at the third epoch, and weathered or oxidized at the fourth epoch.
2022-09-08T22:39:42.649Z
134,701,449
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.19110/2221-1381-2018-1-19-24", "MAG": "2804067148", "PubMedCentral": null }, "license": null, "status": "BRONZE", "url": "https://doi.org/10.19110/2221-1381-2018-1-19-24" }
Êîìпëåкñîì ìåòîдîв (ñвåòîвàя è эëåкòðîííàя ìèкðîñкîпèя, ðåíòãåíîвñкàя ìèкðîòîìîãðàфèя) èзó÷åíî ðàñпðåдåëåíèå è ìîðфîëîãèя пîð è «кàíàëîв» в àëьбèдíîй òкàíè кîíîдîíòîвых эëåìåíòîв, пðèíàдëåжàщèх к пîздíåдåвîíñкî-ðàííåкàìåííîóãîëьíыì пðåдñòàвèòåëяì îòðядîв Ozarkodinida Dzik 1976 (Mehlina Youngquist, Youngquistognathus Myshkina et Zhuravlev, Polygnathus Hinde, Bispathodus Müller), Prioniodontida Dzik 1976 (Jablonnodus Dzik) è Priniodinida Sweet 1988 (Ligonodina Bassler). Мîðфîëîãèя пîðîвîкàíàëьíîй ñèñòåìы кîíîдîíòîвых эëåìåíòîв дåìîíñòðèðóåò ðàзëè÷èя íà óðîвíå òàкñîíîв ðîдîвîãî ðàíãà, ÷òî пîзвîëяåò пðåдпîëîжèòь вîзìîжíîñòь èñпîëьзîвàíèя эòîãî пðèзíàкà в ñèñòåìàòèкå кîíîдîíòîв. Îòìå÷åííîå дëя ðîдà Youngquistognathus åдèíñòвî в ñòðîåíèè пîðîвî-кàíàëьíîй ñèñòåìы в ðàзëè÷íых эëåìåíòàх àппàðàòà дàåò îñíîвàíèя пðåдпîëàãàòь, ÷òî дàííый пðèзíàк пåðñпåкòèвåí пðè ðåкîíñòðóкöèè àппàðàòîв пî ðàзðîзíåííыì эëåìåíòàì. Ключевые слова: кîíîäîíты, гèстîлîгèя, пîçäíèй äåвîí.
2022-02-09T12:00:57.730Z
83,771,259
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.11606/ISSN.2318-3659.V33I2P67-71", "MAG": "1812230086", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Foram utilizadas 43 pecas de caes sem raca definida, sendo 30 delas dissecadas e as 13 restantes submetidas a processo de corrosao. As arterias da base do encefalo estudadas estao na dependencia de duas grandes fontes principais representadas, uma delas pela arteria basilar (sistema vertebro-basilar) e, a outra, pelas arterias carotidas internas esquerda e direita (sistema carotico); considerou-se, ainda, a  possibilidade de ocorrencia de fonte auxiliar, representada pelas anastomoses existentes entre a arteria maxilar e a arteria carotida interna. A particular disposicao dos ramos das arterias carotidas internas e dos ramos terminais da arteria basilar determina formacao de um circuito arterial do encefalo que, a partir da divisao da arteria carotida interna, de ambos os lados, em seus ramos terminais, rostral e caudal, apresenta-se rostralmente de modo invariavel, em pequeno arco ou ferradura de concavidade caudal; caudalmente de forma variada, constitui figura piriforme (56,6%) ou poligonal (43,3%) constituida, rostralmente, pelas arterias cerebrais rostrais esquerda e direita, lateralmente, pelos ramos rostral e caudal das arterias carotidas internas esquerda e direita e, caudolateralmente, pelos ramos terminais (a esquerda e a direita) da arteria basilar. O padrao vascular das arterias da base do encefalo dos caes estudados situa-se entre os tipos 2a e 23, referidos por De Vriese (1905) e entre os estagios medio e final de seu desenvolvimento  filogenetico, considerado p o rT e stu t13(1911).
2022-12-02T11:47:18.004Z
244,032,955
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3390/nano11113019", "MAG": null, "PubMedCentral": "8625597" }, "license": "CCBY", "status": "GOLD", "url": "https://www.mdpi.com/2079-4991/11/11/3019/pdf?version=1637749819" }
Chitosan is one of the most well-known and characterized materials applied in tissue engineering. Due to its unique chemical, biological and physical properties chitosan is frequently used as the main component in a variety of biomaterials such as membranes, scaffolds, drug carriers, hydrogels and, lastly, as a component of bio-ink dedicated to medical applications. Chitosan’s chemical structure and presence of active chemical groups allow for modification for tailoring material to meet specific requirements according to intended use such as adequate endurance, mechanical properties or biodegradability time. Chitosan can be blended with natural (gelatin, hyaluronic acid, collagen, silk, alginate, agarose, starch, cellulose, carbon nanotubes, natural rubber latex, κ-carrageenan) and synthetic (PVA, PEO, PVP, PNIPPAm PCL, PLA, PLLA, PAA) polymers as well as with other promising materials such as aloe vera, silica, MMt and many more. Chitosan has several derivates: carboxymethylated, acylated, quaternary ammonium, thiolated, and grafted chitosan. Its versatility and comprehensiveness are confirming by further chitosan utilization as a leading constituent of innovative bio-inks applied for tissue engineering. This review examines all the aspects described above, as well as is focusing on a novel application of chitosan and its modifications, including the 3D bioprinting technique which shows great potential among other techniques applied to biomaterials fabrication.
2022-12-12T19:06:04.071Z
119,899,898
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1364/JOSAB.29.002329", "MAG": "1969037776", "PubMedCentral": null }, "license": null, "status": null, "url": null }
We report on our numerical work concerning a planar metamaterial exhibiting classical electromagnetically induced transparency (EIT). Using a structure with two asymmetric short strips, we demonstrate that an EIT-like resonance with a high quality factor can be achieved and this high quality factor leads to a large group index of the order of 700. The operation of metamaterial at low temperatures is anticipated to be a promising path towards low-loss metamaterials since nonradiative losses are strongly suppressed. By decreasing temperature from 300 K to 100 K, a controlled behavior with a 26% increase in the quality factor of the resonance and an 85% increase in the group index was observed.
2022-12-21T18:11:06.476Z
123,420,413
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1017/S0022112007006398", "MAG": "2099513219", "PubMedCentral": null }, "license": null, "status": null, "url": null }
We report the results of an experimental study of the finite-amplitude thresholds for transition to turbulence in a constant mass flux pipe flow. The flow was perturbed using small impulsive jets and push–pull disturbances from holes in the pipe wall. The flux of the disturbance is used to define an amplitude for the perturbation and the critical value required to cause transition scales in proportion to Re−1 for jets. In this case, the transition is catastrophic and the scaling suggests a simple balance between inertia and viscosity. On the other hand, the threshold scales as Re−1.3 or Re−1.5 for push–pull disturbances with the precise value depending on the orientation of the perturbation. Further, the amplitudes required to cause transition are typically an order of magnitude smaller than for jets. When the push–pull perturbation was applied in the oblique direction, streaks and hairpin vortices appeared during the growth phase of the disturbance. The scaling of the threshold and the growth of structures are both consistent with ideas associated with temporary algebraic growth.
2022-12-29T17:59:05.915Z
152,230,608
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1590/2176-457326367", "MAG": "2560313056", "PubMedCentral": null }, "license": "CCBY", "status": "GOLD", "url": "http://www.scielo.br/pdf/bak/v12n1/en_2176-4573-bak-12-01-0131.pdf" }
The purpose of this article is to discuss the possible relationships between two theoretical trends of the early 20th century: Bakhtin’s dialogism and Vossler’s stylistics. Despite not mentioning Vossler’s theory in his grammar teaching notes, Bakhtin does include it in his classroom practice with some variations, which is a result of the dialogue between the two. Thus, this article aims to analyze Vossler’s theory so as to observe how Bakhtin interacts with Vossler’s concepts of grammar and style and to consider the extent to which some of these concepts are used in his classroom notes.
2022-12-23T02:19:04.669Z
109,961,486
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1049/EL:19760112", "MAG": "2096531866", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Calculations of maximum generated r.f. powers are presented for GaAs single-drift Read, double-drift Read and hybrid Read structures at 10 GHz. The single-drift Read diode gives the highest output power in c.w. applications, and the double-drift design is superior in pulsed operation.
2022-02-10T05:32:59.376Z
24,801,716
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/APS.2012.6348705", "MAG": "2080601034", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This paper presents surface distortion detection and identification using bipolar measurements and microwave holography on a compact sub-reflectarray Cassegrain system. A ring-type distortion is added to the Cassegrain system which affects the performance of the overall system. Using microwave holographic diagnostics and measurements, the ring distortion is identified and its effect on the overall system is analyzed.
2022-02-12T18:26:10.701Z
97,568,271
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1081/SCC-120034175", "MAG": "2088360007", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Abstract Ring oxygenated coumarins were obtained in a single‐step by condensation of appropriately substituted phenols with acetylenic esters by catalytic amounts of indium chloride in the absence of solvent.
2022-09-01T03:51:33.441Z
154,026,870
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2747/1538-7216.45.6.429", "MAG": "2031654130", "PubMedCentral": null }, "license": null, "status": null, "url": null }
A prominent American specialist on the Russian economy comments on economic policy under Putin in light of a preceding paper on the subject by Anders Åslund. While suggesting that Åslund's paper represents "a remarkably detailed and convincing description of Vladimir Putin's economic reform," the author proceeds to counter most aspects of Åslund's characterization and analysis. Russia's economic growth since Putin's ascent to power is largely attributed to the jump in world oil prices and windfall profits from oil exports. Journal of Economic Literature, Classification Numbers: E60, E63, F13, H20, H60, P21. 1 figure, 1 table, 9 references.
2022-09-13T08:35:55.801Z
246,552,192
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.22162/2587-6503-2021-3-19-170-181", "MAG": null, "PubMedCentral": null }, "license": null, "status": "BRONZE", "url": "http://kigiran.com/pubs/index.php/bul/article/download/1802/2136" }
Introduction. The memory of the Great Patriotic War is preserved by all post-Soviet nations. In this war, virtually every family had a member lost, and his/her destiny often remained unknown. So, the Russian Ministry of Defense decided to create online combined databases. Goals. The paper considers the actual problems of digitization, systematization, law and technical implementation tackled by developers of the databases. Results. The three online resources on the Great Patriotic War — Memorial (documents on irrecoverable casualties), Podvig Naroda (Russ. ‘feat of nation’, materials on awards), and Pamyat Naroda (Russ. ‘people’s memory’, a generalizing engine containing, in addition to the above mentioned, operational data on hostilities) — made it possible to the public to gain access to the multiple documents housed by different archives. Meanwhile, the difficulties to have been settled were not reduced to huge amounts of materials to be processed only. Many documents from departmental archives have not been declassified yet. The law side of the issue does not allow publishing all information. The creation and maintenance of these systems are an important experience required for the further digitization of archived documents.
2022-10-28T01:02:49.985Z
85,568,674
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2337/diab.43.12.1407", "MAG": "2118465860", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This study investigated the neurobehavioral effects of mild and moderate hypoglycemia in adults with insulin-dependent diabetes mellitus (IDDM). On 2 consecutive days, 26 subjects were tested in a counterbalanced, randomized, single-blind, crossover design. On the experimental day, subjects performed tests at 6.4, 3.6, and 2.6 mmol/l and again after glycemic recovery to 6.3 mmol/l. On the control day, subjects performed tests four times at euglycemia. Three months after testing, 15 subjects repeated the experimental day protocol. Results demonstrated that both mild and moderate hypoglycemia significantly disrupted performance. However, performance deterioration varied substantially across individual subjects. Men exhibited significantly more deterioration than women at mild hypoglycemia, and subjects with a history of unconsciousness due to hypoglycemia exhibited more deterioration than subjects with no such history. Individual deterioration scores during repeat testing significantly correlated with performance during original testing. Recovery from hypoglycemia-related impairment varied across individuals and was correlated with degree of impairment during hypoglycemia. These results suggest that the glycemic threshold for onset and recovery from neurobehavioral deterioration with hypoglycemia, as well as degree of impairment experienced, varies across individuals. Furthermore, these individual differences are stable across time.
2022-12-04T00:02:12.476Z
12,705,944
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1128/aem.10.1.74-78.1962", "MAG": "2120556087", "PubMedCentral": null }, "license": null, "status": "GOLD", "url": "https://doi.org/10.1128/aem.10.1.74-78.1962" }
A method has been presented for evaluating the effectiveness of fabrics treated with antimicrobial agents to resist growth of contaminating organisms. The method consists of direct inoculation of the fabric with suitable test organisms and the subsequent enumeration of growing colonies which develop when the fabric is implanted in a nutrient medium. The method is sensitive, versatile, easy to perform, highly reproducible, and realistically evaluates the practical effectiveness of residual antimicrobial agents on fabrics. Data are given which demonstrate the sensitivity of the method to small differences in antimicrobial concentrations. The versatility of the method is shown by the variety of antimicrobial agents and organisms which have been utilized. Both bacteriostatic and bactericidal activity can be evaluated.
2022-12-21T06:57:13.555Z
120,746,229
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1063/1.1701390", "MAG": "1971130512", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The nuclear spin relaxation times T1 and T2 have been calculated for two identical nuclei of spin I = ½ fixed in an ellipsoid undergoing rotational Brownian motion. The ellipsoid is subject to small random changes in orientation in which the rotation probabilities about its three major axes are different. This anisotropic motion yields five nuclear correlation times; isotropic motion yields only one correlation time. The results are applicable provided that the static dipolar coupling is effectively averaged to small values by the rotational motion. For nonviscous liquids, T1 = T2. When the rotation probabilities about two axes are equal, the relaxation‐time expressions simplify a great deal, but they retain the essential relaxation features of anisotropic rotational motion; the number of nuclear correlation times is reduced to three; the relaxation times for rapid motion have been calculated as a function of the ratio of the two rotation probabilities for this case. The relaxation rates in ellipsoids of ...
2022-12-25T06:49:02.605Z
219,700,681
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2196/16720", "MAG": "3009099078", "PubMedCentral": "7325000" }, "license": "CCBY", "status": "GOLD", "url": "https://jmir.org/api/download?alt_name=mhealth_v8i6e16720_app1.pdf&filename=f400b3f0db8dd7e6e927e096769f73bf.pdf" }
BACKGROUND Web-based and mobile interventions to influence physical activity behavior have had limited effects on sustained behavior change. One reason may be that the interventions aim to change largely habitual behavior. Following an identity-oriented approach could be a successful strategy to behavior change because people are committed to behave in line with their self-perception of identity. OBJECTIVE In this paper, we take a closer look at the role of motivation in long-term adherence to lifestyle interventions. The paper outlines a method for web-based or mobile intervention development that allows exploration of integrating behavior change theory into the design process. We will describe the development of a mobile app that allows people to be self-determined and to value and self-regulate physical activity by adopting an identity-oriented approach. METHODS This paper describes a Research through Design (RtD) process in which design activities are carried out as part of the knowledge-generating process. Two RtD phases were completed, followed by a conceptual design phase. In the first RtD phase, 8 participants used diary cards to study initial attitudes toward starting with small changes in physical activity. In the second RtD phase, 26 participants used a web-based app to study changes in physical activity. We used an adapted version of the Self-Report Habit Index (SRHI) to evaluate individuals' perceptions of a particular behavior with respect to the three facets of a habit. The conceptual design phase consolidated the results from first two RtD phases into a design of a mobile app that combines an identity approach with gamification principles. The conceptual design was evaluated in a user-experience study with 4 participants. RESULTS In the first RtD phase, we found that interacting daily with diary cards and reflecting on physical activity patterns is a promising strategy but works better through a digital medium. In the second RtD phase, SHRI ratings from all participants generally increased each week. In the conceptual design phase, we found that the concept of the mobile app was positively evaluated by participants. However, participants mentioned that terms such as "identity" do not resonate with them and that scenarios could be simpler. CONCLUSIONS This paper provides deeper insights into designing for electronic health (eHealth) interventions and services and suggests a new way that motivation can be shaped by the design of an intervention and adherence to physical activity. To the best of our knowledge, this was the first iterative design study in which the effects of adopting an identity approach to both motivation and physical activity were included and observed. Initial promising results were found for using a web-based intervention where habits and identification with the personal importance of a behavior were repetitively triggered.
2022-12-30T00:27:40.755Z
229,936,762
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.29252/iors.10.1.43", "MAG": "3046979057", "PubMedCentral": null }, "license": null, "status": "GOLD", "url": "http://iors.ir/journal/files/site1/user_files_ba3acb/iorsadmin99-A-10-1422-9-b4b5944.pdf" }
Nowadays, airline industries should overcome different barriers regarding the fierce competition and changing consumer behavior. Thus, they attempt to focus on joint decision making which enables them to set pricing and capacity allocation to maximize their profits. In this research, we develop a model to optimize pricing and capacity allocation in a duopoly of single-flight leg for two competitive airlines. The problem considers actual assumptions about flexible partitions in flight’s cabins and additionally demand uncertainty. There is a flexible partitioning of business and economy cabins and demand is assumed price-dependent with additive uncertainty. The capacity and pricing decisions are simultaneously determined through indirect channels. Moreover, a numerical study is developed to investigate how market components and competition conditions change pricing, capacity, and profit levels. The results show that increasing market volume like decreasing price sensitivity provides higher levels of price and profits. Moreover, intensified competition never leads to higher prices. Thus, a competitive network of airlines provides better impact on market mechanism to achieve competitive prices for both economy and business classes.
2022-02-07T22:52:31.820Z
137,205,689
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1117/12.429416", "MAG": "2043455944", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Using Si VLSI technology, we can fabricate various kinds of infrared focal plane arrays (FPAs) which cover spectral bands from short wavelength infrared to long wavelength infrared. The Si-based technology offers many attractive features, such as monolithic integration, high uniformity, low noise, low cost, and high productivity. We have been developing Si-based infrared FPAs for more than 20 years and have verified their usefulness.
2022-09-01T05:26:51.656Z
128,899,511
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1071/SR9680067", "MAG": "2048883440", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The soil-water diffusivity was determined as a function of water content for Urrbrae fine sandy loam treated with two fatty alcohols, two amines, Krilium, polyvinyl alcohol, and Carbowax. The fatty alcohols and dodecylamine had the strongest influence on soil-water diffusivity throughout the whole range of soil-water contents. Treatment with these amendments markedly reduced capillary flow of water to the soil surface. Dodecylamine reduced the rate of infiltration into the soil. Heats of wetting of the treated soil samples indicated that penetration rate and diffusivity near saturation were reduced in accordance with the hydrophobic character of the adsorbed compound. Cetyl alcohol was partly desorbed when water permeated through cetyl-alcohol-treated soil, forming a film on the advancing wetting front. This resulted in a slower rate of penetration than would have been expected from the hydrophobic character of the complex.
2022-09-09T01:38:13.918Z
33,533,261
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1364/OL.19.002161", "MAG": "2065122366", "PubMedCentral": null }, "license": null, "status": null, "url": null }
We propose, analyze, and demonstrate a hybrid wavelength-and-angle-multiplexed optical data storage system. Our system utilizes multiwavelength information processing in conjunction with angle-multiplexed volume holographic storage, achieving direct compatibility with wavelength-encoded optical logic processors. Such a scheme also allows for rapid recall of high-density data into electronic processing and display systems. Hybridization of wavelength and angle multiplexing relaxes demands on spectral and angle-tuning sources and allows for the use of present-day-available optical sources and components.
2022-09-15T00:53:45.132Z
236,529,286
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1155/2021/9961089", "MAG": null, "PubMedCentral": "8324356" }, "license": "CCBY", "status": "GOLD", "url": "https://doi.org/10.1155/2021/9961089" }
Artemisia absinthium L. (Asteraceae) is traditionally used for gastrointestinal ailments and disorders linked to numerous risk factors including microbial infections. We aimed to provide contemporary evidence for its ethnopharmacological use and determine its antimicrobial capacity and mode of action, cytotoxicity, and phenolic constituents. Ethnopharmacological survey was conducted using semistructured interviews. Antimicrobial and antibiofilm capacities were determined by microdilution/crystal violet assay, respectively. Modes of action tested include estimation of exopolysaccharide production (congo red binding assay) and interference with membrane integrity (crystal violet uptake and nucleotide leakage assay). Cytotoxicity was determined using crystal violet assay. Polyphenolic profiling was done by advanced liquid chromatography/mass spectrometry (UHPLC-LTQ OrbiTrap MS). Artemisia absinthium in Serbia is traditionally used for gastrointestinal disorders, among others. Further study revealed high antifungal capacity of herb ethanolic extract towards range of Candida species (MIC 0.5–1 mg/mL) along with promising antibacterial activities (MIC 0.25–4 mg/mL). Interference with membrane integrity could be observed as a possible antimicrobial mechanism. Antibiofilm potential can be considered as high (towards C. krusei) to limited (towards P. aeruginosa) and moderate based on reduction in exopolysaccharide content. In concentrations up to 400 µg/mL, no cytotoxicity was observed towards HaCaT and HGF-1 cell lines. Polyphenolic analysis revealed twenty-one different constituents. A. absinthium usage as a gastrointestinal ailment remedy has been confirmed in vitro by its antimicrobial capacity towards microorganisms whose presence is linked to the diseases and associated complications and noncytotoxic nature of the natural product. The observed activities could be attributed to the present phenolic compounds.
2022-12-14T22:19:50.137Z
240,813,909
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.21673/anadoluklin.708151", "MAG": null, "PubMedCentral": null }, "license": "CCBYNC", "status": "GOLD", "url": "https://dergipark.org.tr/tr/download/article-file/1027052" }
Morbidity and mortality rates are increasing day by day in relation to the COVID-19 infection seen in China in December and announced as a pandemic. Concerns about the pregnancy process increase with the epidemic. The clinical manifestations of the general population are similar to those of pregnant women who have had COVID-19 pneumonia. Because the pregnant women are more sensitive to respiratory pathogens and severe pneumonia, the process should be maintained in a more controlled manner due to the low number of cases. It was emphasized that the IPC measures proposed by the world health organization should be implemented by pregnant women, as well as those in abortus, fetal loss, postpartum period, and those who take care of the baby. Although there is not enough evidence in the studies conducted, it was stated that the transition of the disease from mother to baby is by vertical transmission. It is recom-mended that pregnant women with infection or suspicion should not be kept in close contact with their baby for at least 14 days after birth and not breastfeeding. It is stated that if there is no medical indication for delivery, it can be done vaginally. Pregnant women should be handled with a multidisciplinary approach consisting of obstetric, perinatal, newborn and intensive care specialists during the infection process. Also, providing psychosocial support to pregnant women is very important in this process.
2022-12-18T04:03:10.742Z
225,994,507
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.9771/CGD.V6I1.36211", "MAG": "3033063188", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Este artigo produto de uma pesquisa de pos-doutorado desenvolvida por Melo, que contou com apoio da graduanda Nobrega Costa, em iniciacao cientifica. Apresentamos aqui a avaliacao de oficinas realizadas em comunidades indigenas, quilombolas e em escolas da rede publica do entorno de Florianopolis, desenvolvidas no âmbito do  PROEXT/MEC/SECADI, de 2012 a 2015.. Destarte,  o presente artigo pretende trazer um panorama dos resultados dessas oficinas, partindo de uma contextualizacao pelas demandas das Acoes Afirmativas na Universidade Federal de Santa Catarina em direcao a reflexoes sobre como esses programas de extensao contribuiram para o contexto atual de inclusao de academicos indigenas, quilombolas e da rede publica nesta Universidade.. Finalmente, apontamos para importância da extensao universitaria como um pilar basico para todas as ciencias, sendo produtora de relacoes e de redes distintas. E nesse caminho da Antropologia em extensao que se pode pensar em uma Antropologia interessada politicamente com os sujeitos que ela estuda, “comprometida”, apoiando-se, ainda, na indissociabilidade entre ensino-pesquisa-extensao.
2022-12-19T07:22:42.403Z
213,429,018
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/23802359.2019.1711220", "MAG": "2999859175", "PubMedCentral": "7748873" }, "license": null, "status": "GOLD", "url": "https://www.tandfonline.com/doi/pdf/10.1080/23802359.2019.1711220?needAccess=true" }
Abstract In this study, the complete mitochondrial DNA sequence of a hagfish Eptatretus sp. Nan-Hai from a depth of 1000 m is presented. The complete sequence was determined using next-generation sequencing and long PCRs. The mitochondrial genome of Eptatretus sp. Nan-Hai is 17,538 bps in size and composed of 13 protein-coding genes, two ribosomal RNA genes, 22 transfer RNA genes, and one control region (D-loop). The base composition of mitochondrial genome is biased toward A + T content, at 67.21%, with GC skew of −0.35 and AT skew of −0.03. A phylogenetic tree revealed that within the genus Eptatretus, Eptatretus sp. Nan-Hai is closely related to Eptatretus atami.
2022-12-30T00:26:42.137Z
245,607,773
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.22337/2587-9618-2021-17-4-22-39", "MAG": null, "PubMedCentral": null }, "license": "CCBYNCSA", "status": "GOLD", "url": "https://ijccse.iasv.ru/index.php/ijccse/article/download/418/266" }
A review of the most significant domestic and, due to numerical superiority, foreign works on physical modelling of snow transport and snow accumulation processes, in particular, for the purpose of determining snow loads on roofs with arbitrary geometry, is presented. The existing practice of development of recommendations on assignment of snow loads in Russian laboratories is considered and critically evaluated. Comparison of do-mesticworks with scientific articles in the advanced world scientific journals and foreign regulatory documents leads to unfavorable conclusions. Recommendations on assigning snow loads, issued by Russian laboratories on the basisof extremely outdated and poorly substantiated methodology, bear a serious risk for evaluating mechan-ical safety of modern structures, for which such recommendations are developed. Recommendations are offered to remedy this current dangerous practice. The article also gives some suggestions on forming a basis for field observations of snow loads on existing roofs.
2023-01-01T19:17:11.106Z
143,725,810
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1086/211821", "MAG": "1997650078", "PubMedCentral": null }, "license": null, "status": "BRONZE", "url": "http://www.journals.uchicago.edu/doi/pdfplus/10.1086/211821" }
The study of Homeric religion cannot well be disassociated from the study of Homeric society in general. Scarcely another factor in societal life is so, all-pervasive in its influence as is the system of beliefs that develop out of man's relations with his "imaginary environment"; no religion can be studied to much purpose apart from the scrutiny of its setting in the general societal order. Further, a good many of the points upon which I shall touch apply just as aptly to the general study of Homer as they do to the specific topic of Homeric religion. These considerations must serve as an apology, if one is thought to be needed, for the fact that this essay seems, largely to ignore the precise theme set before it. What I have found myself writing -after the end is reached and the time has come to think of a beginning-is a series of reflections upon the study of Homer, chiefly with reference to, Homeric religion, and never, I trust, without some evident applicability to it. It should also be said, by way of preliminary, that Homeric evidence, so far as this essay is concerned, means the evidence of the Iliad and the Odyssey. The whole matter of the timerelation as between the data of classical archaeology and those of the epics is dubious enough to give the discreet layman pause. And the "Homeric Age" of the Homeric poems is a sufficiently rich and definite culture-epoch to reward any effort that sociologists may choose to put upon it. There are a number of reasons why the study of Homer is profitable to the real scientist whose interest lies in the life and evolution of human society-and it is, in any case, an enticing study by reason of the character of its materials. Perhaps it is a little outside of the scientific order to reveal a weakness for data presented in attractive form; but if the mood of the investi-
2022-09-08T12:32:50.177Z
32,318,943
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1097/00002826-199502000-00007", "MAG": "2036642540", "PubMedCentral": null }, "license": null, "status": null, "url": null }
We measured homovanillic acid (HVA), 5-hydroxy indole acetic acid (5-HIAA), and tryptophan (TP) in cerebrospinal fluid (CSF) of 20 neuroleptic-free patients with Huntington's disease (HD), and compared mean values with those from four control groups including 15 normal individuals, 38 patients with dystonia, 23 untreated patients with Parkinson's disease, and 61 patients with other neurological diseases (ONDs). The mean levels of HVA in the CSF of patients with HD were reduced compared with those from normal controls (p < 0.001), dystonic patients (p < 0.005), individuals with ONDs (p < 0.0001), and even from untreated parkinsonian patients (p < 0.05). 5-HIAA and TP levels in the CSF of patients with HD were not significantly different from those in the CSF of control patients. Our data suggest a reduced dopamine neurotransmission in HD and may account for the bradykinesia observed in our patients.
2022-10-05T16:28:14.192Z
235,899,334
{ "externalids": { "ACL": null, "ArXiv": "2107.07149", "DOI": "10.1103/PhysRevB.104.125427", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
The electric structure of twisted bilayer GeSe, which shows a rectangular moiré pattern, is analyzed using a k · p type effective continuum model. The effective model is constructed on the basis of the the local approximation method, where the local lattice structure of a twisted bilayer system is approximated by its untwisted bilayer with parallel displacement, and the required parameters are fixed with the help of the first-principles method. By inspecting the twist angle dependence of the physical properties, we reveal a relation between the effective potential under moiré pattern and the alignment of the Ge atoms, and also the resultant one-dimensional flat band, where the band is flattened stronger in a specific direction than the perpendicular direction. Due to the relatively large effective mass of the original monolayers, the flat band with its band width as small as a few meV appear in a relatively large angle. This gives us an opportunity to explore the dimensional crossover in the twisted bilayer platform.
2022-10-07T00:12:06.833Z
36,620,272
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1364/OE.23.003010", "MAG": "2001922107", "PubMedCentral": null }, "license": null, "status": null, "url": null }
A one-dimensional micro-bending vector sensor based on two-mode interference has been introduced. This device was fabricated by lateral offset splicing a piece of six-air-hole grapefruit microstructure fiber (GMF) with single mode fiber (SMF). Variation of effective mode index occurred by micro-bending was investigated in simulation and experiment. This device exhibits micro-bending sensitivities of 0.441 nm/m(-1) and -0.754 nm/m(-1) at 0° and 180° bending orientations, respectively. Moreover, this sensor is immune to surrounding refractive index (SRI) and presents a low crosstalk of temperature.
2022-12-11T10:17:36.974Z
199,607,329
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.26502/acmcr.96550094", "MAG": "2964143773", "PubMedCentral": null }, "license": null, "status": "GOLD", "url": "https://doi.org/10.26502/acmcr.96550094" }
Acquired hemophilia A (AHA) is a rare and severe bleeding disorder characterized by the development of autoantibodies against factor VIII. There is no previous study published in our country for AHA. The aim of this study that to describe the clinical symptoms, diagnostic criteria and treatment strategies in patients with AHA in the south of Tunisia. We retrospectively collected all patients diagnosed with AHA in the Department of Hematology of Hedi Chaker Hospital (Tunisia) from 2000 to 2017. The diagnosis was established in the presence of clinical hemorrhagic features associated with the isolated prolongation of the activated partial thromboplastin time (APTT), not corrected after two hours by incubating patient plasma with equal volumes of normal plasma, and with factor VIII less than 50%. We collected five patients with AHA in the South of Tunisia. There were 4 females and 1 male with the median age of 32 years old. The median FVIII C was 7% and the median value of FVIII inhibitor was 11 UB. The most common clinical symptoms were post-partum hematoma in 3 patients (60%), extensive cutaneous hematoma in one patient and hemorrhagic tooth extraction in one patient. All patients were treated in first-line therapy with bypassing agent FVIIa with successful response in 80% of cases. The first-line treatment of bleeding in AHA requires a bypassing agent and the optimal therapeutic strategy to eradicate the inhibitor include immunosuppression with corticosteroids alone or corticosteroids in combination with cyclophosphamide.
2022-02-08T05:36:31.023Z
20,822,867
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1111/j.1440-1754.2005.00631.x", "MAG": "2047853716", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Objective:  To determine whether unrecognized obstructive sleep apnoea (OSA) is present in some children diagnosed with normal variant short stature.
2022-09-02T03:59:53.108Z
198,962,843
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1055/s-0039-1693710", "MAG": "2965065568", "PubMedCentral": "6660472" }, "license": "CCBY", "status": "GOLD", "url": "http://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0039-1693710.pdf" }
Hereditary hemorrhagic telangiectasia (HHT) is a vascular dysplasia characterized by recurrent and spontaneous epistaxis (nose bleeds), telangiectases on skin and mucosa, internal organ arteriovenous malformations, and dominant autosomal inheritance. Mutations in Endoglin and ACVRL1 / ALK1 , genes mainly expressed in endothelium, are responsible in 90% of the cases for the pathology. These genes are involved in the transforming growth factor-β(TGF-β) signaling pathway. Epistaxis remains as one of the most common symptoms impairing the quality of life of patients, becoming life-threatening in some cases. Different strategies have been used to decrease nose bleeds, among them is antiangiogenesis. The two main angiogenic pathways in endothelial cells depend on vascular endothelial growth factor and fibroblast growth factor (FGF). The present work has used etamsylate, the diethylamine salt of the 2,5-dihydroxybenzene sulfonate anion, also known as dobesilate, as a FGF signaling inhibitor. In endothelial cells, in vitro experiments show that etamsylate acts as an antiangiogenic factor, inhibiting wound healing and matrigel tubulogenesis. Moreover, etamsylate decreases phosphorylation of Akt and ERK1/2. A pilot clinical trial (EudraCT: 2016–003982–24) was performed with 12 HHT patients using a topical spray of etamsylate twice a day for 4 weeks. The epistaxis severity score (HHT-ESS) and other pertinent parameters were registered in the clinical trial. The significant reduction in the ESS scale, together with the lack of significant side effects, allowed the designation of topical etamsylate as a new orphan drug for epistaxis in HHT (EMA/OD/135/18).
2022-09-10T07:38:07.197Z
119,231,666
{ "externalids": { "ACL": null, "ArXiv": "1203.2420", "DOI": "10.22323/1.168.0013", "MAG": "2515145488", "PubMedCentral": null }, "license": "CCBYNCSA", "status": "HYBRID", "url": "https://pos.sissa.it/168/013/pdf" }
The ALICE experiment at the LHC has collected wealthy data in proton-proton and lead-lead collisions. An overview of recent ALICE results is given in this paper. Hadron spectra measured in pp collisions at $\sqrt{s}=0.9$, 2.76 and 7 TeV are discussed. Properties of hot nuclear matter produced in Pb-Pb collisions at $\sqrt{s_{NN}}=2.76$ TeV, revealed via many observables measured with the ALICE experiment, are shown.
2022-09-12T12:04:52.202Z
251,628,834
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/IC-MAM55200.2022.9855378", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
In this paper, microwave characterizations and phase-shifting applications of electrophoretically deposited thick films and sol-gel derived thin films of Barium Strontium Titanate (BST) are presented. Capacitors fabricated using Ba0.7Sr0.3TiO3 films prepared by electrophoretic deposition (EPD) on platinum foils and sol-gel technique on platinized Si and SiO2 demonstrate a maximum tunability of 49%, 29%, and 33%, respectively. The nominal capacitance and the microwave loss tangent are obtained from 500 MHz to 6 GHz. The three different BST films are designed to fabricate phase shifters. The total phase shift divided by the maximum insertion is 10°/dB higher in phase shifters developed with thin films on SiO2 than in thick films. The linearity of the RF phase shifters using an input power from −20 dBm to 4 dBm is also analyzed. The linearity of the RF phase shifters using an input power from −20 dBm to 4 dBm is also analyzed. For the first time, the two methods of film deposition are directly compared in microwave applications.
2022-08-19T22:31:35.151Z
31,592,796
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1159/000120306", "MAG": "2075930386", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The term beagle puppy has been used extensively as an experimental model of intraventricular hemorrhage (IVH) in the preterm infant. Fourteen variables were selected which were considered theoretically important to both the model and the preterm infant, and the data were subjected to discriminant analysis. Use of only three variables in combination correctly predicted whether an animal would sustain germinal matrix hemorrhage: baseline blood pressure, Pco2, and temperature. The model does not involve ischemia, which appears to be the sentinel but not singular insult in the IVH of preterm infants.
2022-12-14T10:52:25.625Z
215,871,216
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1108/lm-06-2019-0035", "MAG": "3011425060", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This study examined the interceding influence of work–life balance (WLB) among library staff at the Kenneth Dike Library and its implication for the provision of information. The research sought to respond to the following questions: the effect of demographic variables on the WLB of librarians and their perceptions of WLB within the intimate environment.,This study adopted a positivist research paradigm because the nature of the research revealed a single social reality which can be measured quantitatively, using a reliable instrument such as a questionnaire. The total sampling technique was used to zero in on the staff of the library, in which the entire library population was included in the study.,The findings suggest that male librarians enjoy a better WLB than their female counterparts. Also, the results indicate that librarians, irrespective of their marital status, focused on job-related activities minding their marital status and therefore, marital status could influence the WLB of librarians. Similarly, priority is not being given to their work, to the detriment of caring for the family.,The study suggests that age causes the WLB to change, the implication being that an ageing workforce has an impact on adaptation, output and innovation.,This paper sheds light on the WLB among librarians at the Kenneth Dike Library (KDL); therefore, information acquired from this study is imaginative and valuable to understand better how information professionals react to official and personal engagement.
2022-12-17T17:18:57.998Z
53,477,837
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1103/PHYSREVSTAB.18.020702", "MAG": "2329431696", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This paper studies various mechanisms to enhance the coherent Smith-Purcell radiation (SPR) at terahertz frequencies using particle-in-cell (PIC) simulations. A simple analytical dispersion relation is derived to predict the frequency of the evanescent surface wave of the open grating, which is excited by a backward-wave oscillation mechanism and emits radiation at harmonics of this frequency, and the cavity mode frequencies of the Orotron-like device, all in excellent agreement with the simulation data. The grating parameters are optimized to minimize the starting current of a continuous electron beam for exciting coherent SPR. It is demonstrated that a prebunched beam can be used to selectively excite coherent SPR at desired SPR angle and frequencies that are higher harmonics of the beam bunching frequency, where the starting current requirement is eliminated. Our PIC simulations show the dynamics of modes development and competition for the Orotron-like open cavity structure, which owns a lower starting current than the surface mode process. This oscillation mode dominates at steady state and enhances the radiated power by more than 2 orders of magnitude. DOI: 10.1103/PhysRevSTAB.18.020702 PACS numbers: 41.60.Cr, 41.75.Ht
2022-12-21T18:03:58.765Z
16,288,887
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/HAPTICS.2014.6775454", "MAG": "2004685661", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Passivity based approaches to bilateral teleoperation control ensure robust stability against disruptive effects of communication delays. These approaches, while achieving velocity tracking, cannot guarantee position tracking in general. Recently, the Time Domain Passivity Approach (TDPA) has been gaining interest in field of bilateral teleoperation due to its simplicity, ease of implementation, robustness to communication delays, and adaptive control design which promises less conservative performance than frequency domain passivity approaches. Several techniques have been proposed to counter the position drift with conventional passivity based approaches, but not much work has been done to address the problem of position drift with TDPA based control of teleoperation. We propose a novel position drift compensation architecture employing a virtual dependent energy source which leverages the passivity margins allowed by the communication channel to inject energy and recover position tracking without compromising system passivity. A drift compensation scheme is developed within this architecture that ensures synchronization of master and slave robot trajectories. The proposed method is generalizable to all bilateral teleoperation control architectures, and is robust against different communication delay and remote environment conditions. Experiments are conducted to validate the efficacy of the approach, and demonstrate position tracking with up to 1000 ms round-trip delays in free space motion and hard wall contact scenarios.
2022-12-29T16:31:55.794Z
25,495,860
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1002/ijgo.12318", "MAG": "2752773247", "PubMedCentral": null }, "license": null, "status": null, "url": null }
To construct reference charts for the fetal middle cerebral artery (MCA) peak systolic velocity (PSV,) and the corresponding cord blood hemoglobin values at 24–40 weeks of pregnancy for the identification of fetal anemia.
2022-07-29T10:46:44.093Z
32,095,196
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1253/JCJ.49.997", "MAG": "2041302167", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The role of the renal nerve in influencing the hypothalamo-sympathetic nerve system to regulate the cardiovascular system was studied in normotensive Wistar and spontaneously hypertensive rats (SHR). Renal denervation attenuated pressor and sympathetic nerve responses to electrical stimulation of the hypothalamus without lowering the basal blood pressure at 48 hours after denervated operation. These findings suggest that renal denervation could inhibit the hypothalamo-sympathetic nerve system in normotensive rats. The development of hypertension in SHR was completely inhibited by renal denervation during 2 weeks of observation (from 7 to 9 weeks of age) without increasing water intake and urine volume. Pressor responses to intravenous injection of norepinephrine were not affected by renal denervation. The results show that the antihypertensive effect of renal denervation was not due to the changing of vascular reactivity. Pressor and sympathetic nerve responses to hypothalamic stimulation were strongly diminished in renal denervated rats. These results suggest that renal denervation strongly inhibited they hypothalamo-sympathetic nerve system. It is also suggested that the renal afferent nerve may facilitate the hypothalamo-sympathetic nerve system in regulating blood pressure and that this facilitation may contribute to the development of hypertension in SHR.
2022-09-13T04:44:11.805Z
53,956,085
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2528/PIER13020611", "MAG": "2142323806", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Time domain re∞ectometry (TDR) ofiers the advantage of distributed sensing using a single transmission line sensor. In the present study, a parallel plate type non-invasive TDR sensor for structural health monitoring (SHM) of composites has been designed, modeled and experimentally tested. Five layer unidirectional glass flber/epoxy composite specimens are fabricated. Specimens included a damage initiator in form of a cut in the central ply. The TDR sensor detects sub-surface damage in the composite non-invasively as the efiective dielectric constant of the composite decreases due to the presence of delamination cracks. Previous work done on dielectrostriction is used to model the TDR response to strain changes. Qualitative agreement between theory and experimental results for strain sensing are found.
2022-12-10T09:47:31.037Z
183,589
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.6028/NIST.IR.6746", "MAG": "2790127681", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This paper describes the OpenADE (Open Assembly Design Environment) project, a framework that is addressing issues relating to the development of information-exchange standards for the next generation of assembly-oriented design tools. The OpenADE architecture itself is based on a design workspace that is shared between a variety of agents. These agents interact with the design workspace using existing or proposed standards-based translators. The two main contributions described in this paper are an information flow model that describes the flow of information in the product development process, and a core representation for product development information. The information flow model classifies design information into various types, organizes these types into information states and levels of abstraction, and identifies the various transformations that operate between the information states. The information flow model has been augmented through the development of a product representation core. Together the information flow model and the representation core provide an infrastructure for semanticallymeaningful information exchanges between software tools used to support various product development activities. Although the information flow model was initially developed as part of a requirements analysis for the OpenADE framework, the end result more generally provides a foundation for interoperability in next-generation product development systems. * This work was performed while Professors Shooter and Keirouz were guest researchers at the National Institute of Standards and Technology. + Senior Research Associate, University Professor Emeritus of Civil and Environmental Engineering, Carnegie Mellon University.
2022-12-14T23:50:19.790Z
53,506,589
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1088/0143-0807/33/2/345", "MAG": "2058474276", "PubMedCentral": null }, "license": null, "status": "GREEN", "url": "https://ueaeprints.uea.ac.uk/id/eprint/40728/1/EJP_multipole.pdf" }
The spatial variation in phase and the propagating wave-front of plane wave electromagnetic radiation are widely familiar text-book territory. In contrast, the developing amplitude and phase of radiation emitted by a dipole or multipole source generally receive less attention, despite the prevalence of these systems. There is additional complexity in such cases where, in consequence of retardation, the character and features significantly and progressively change as radiation propagates onwards, from the near-field and out towards the wave-zone. Readily developed analytical representations of the electric field, cast as a function of distance from the source, provide illuminating insights into the most prominent and distinctive properties of radiant electromagnetic emission. Graphical implementations and animations of the results prove particularly instructive in revealing the spatial form and temporal evolution of the emergent electromagnetic fields.
2022-12-16T12:44:41.857Z
75,506,449
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.5035/NISHISEISAI.28.497", "MAG": "2329463651", "PubMedCentral": null }, "license": null, "status": null, "url": null }
One case of restricted mobility of fingers, which was caused by leakage of infusion, was presented.Case 33 years, femaleDiagnosis: ovarian cancer (squamous cell carcinoma)This patient was first seen with a complaint of flexion disturbance of her right fingers.She had a history of leakage of infusion (containing 5-FU, Endoxan, Esquinone and Toyomycin) at the dorsal aspect of her right hand, 3 months ago.Extensive tenolysis of extensor tendon was performed. But, the results was unsatis-factory.We would like to stress, that the leakage of infusion must be strictly avoided.
2022-01-27T14:17:15.976Z
55,881,573
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.15405/EPSBS.2017.05.02.144", "MAG": "2617351872", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Being studied initially in the field of psychopathology, the perfectionism was considered as a personality style characterized by negative aspects like striving to be perfect, self-criticism and also low self-esteem and depression. But the last decade’s research drew up perfectionism as a multidimensional construct which imply personal and social elements, with both positive and negative effects onto performance and development. So, the multidimensional model belonging to Hewitt and Flett (1991) distinguish between self-oriented perfectionism; other-oriented perfectionism, and socially prescribed perfectionism. In the educational field, the perfectionism was studied in relation to academic performance and motivation, to achievement goals and to some negative emotions like anxiety, shame, and guilt. But there are just a small number of studies that analyzed the perfectionism in relation to positive emotions in educational settings. Pekrun, Goetz, Titz, and Perry (2002) indicated that students are experiencing a rich diversity of emotions in different academic contexts. In this study, we explored the self-oriented and the sociallyprescribed perfectionism, in relation to positive and negative test-related emotions, within a group of 187 high school students. Results indicated that, when controlling for academic achievement, hope and pride, but also anxiety, anger and guilt are significantly associated with self-oriented perfectionism and uncorrelated with socially-prescribed perfectionism. Instead, the socially-prescribed perfectionism was correlated but the self-oriented perfectionism was not correlated with hopelessness. © 2017 Published by Future Academy www.FutureAcademy.org.uk
2022-02-11T19:41:32.477Z
35,560,493
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1093/infdis/jiv643", "MAG": null, "PubMedCentral": null }, "license": null, "status": "BRONZE", "url": "https://academic.oup.com/jid/article-pdf/214/3/NP/7939980/jiv643.pdf" }
Maiga Chang, Athabasca University, Canada Larbi Esmahi, Athabasca University, Canada Bob Heller, Athabasca University, Canada Jason Hung, Overseas Chinese University, Taiwan Wu-Yuin Hwang, National Central University, Taiwan Lian Li, Hefei University of Technology, China Hong Lin, University of Houston-Downtown, USA Alexander Vazhenia, The University of Aizu, Japan Jie Chi Yang, National Central University, Taiwan Jialin Yi, Northwestern Memorial Hospital, USA
2022-06-14T09:55:16.182Z
53,544,035
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/DDCLS.2018.8516101", "MAG": "2899270510", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The automatic generation control (AGC) in isolated microgrid with multiple distributed energy resources is concerned in this study. First, the load frequency control (LFC) model of an isolated microgrid, which contains diesel engine generators, super-magnetic magnetic energy storage, wind turbines and photovoltaic power system, is established through the analysis of the power generation characteristics of each distributed generation (DG). The LFC model of an isolated microgrid is built by MATLAB/Simulink with diesel generators as frequency control units. Based on the AGC principle of power grid, the AGC controller of the microgrid system is designed by the Q learning algorithm based on the discount compensation model to complete the frequency control. The simulation results verify the feasibility of the isolated microgrid model, showing the efficient dynamic performance of Q controller by compared with PI controller.
2022-12-16T06:38:11.540Z
250,731,863
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1089/tmj.2021.0529", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
Background: In 2016, the Government of Bangladesh (GoB) established a teleconsultation service called Shastho Batayon to increase access to physicians. During COVID-19 pandemic, health care access became limited due to movement restrictions. In response, GoB made Shastho Batayon toll free, publicized the number through media, increased the number of call center doctors, introduced automated messages on COVID-19 preventive measures, and developed a scoring system to classify risk groups for COVID-19. Objectives and Methods: In this case report, we describe how an existing national teleconsultation service can be utilized in a low- and middle-income country to address primary health care needs during a public health emergency. We conducted secondary analysis of Shastho Batayon service data from January to April 2020. Results: The total calls for doctor's consultation increased during the pandemic. Prepandemic, Shastho Batayon received less than 20,000 calls per month. In March 2020, when the first cases of COVID-19 were confirmed, Shastho Batayon services received 60,811 calls for doctor's consultation, which increased to 125,660 calls in April, 2020. The doctor's consultation for primary care has increased for all conditions. Shastho Batayon services screened 28,944 patients with the influenza-like illness or COVID-19-like symptoms in March and April, 2020, provided preventive measures, advice, and referral to designated hospitals based on a national guideline. Conclusions: In public health emergencies such as COVID-19 pandemic, teleconsultation services can help provide prevention guidelines, debunk misinformation, identify risk categories, and refer people to appropriate service and facilities in a timely manner.
2022-12-17T00:18:19.396Z
220,670,497
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/16506073.2020.1790644", "MAG": "3044242627", "PubMedCentral": null }, "license": null, "status": "GREEN", "url": "https://europepmc.org/articles/pmc7581554?pdf=render" }
ABSTRACT The present study examined the underlying role of anxiety sensitivity in the association between effortful control and anxiety and depressive symptoms in a sample of clinically anxious children. It was hypothesized that effortful control would exert an indirect effect through anxiety sensitivity in relation to child anxiety and depressive symptoms. Clinically anxious children (N= 105; M age = 10.09 years, SD = 1.22; 56.7% female; 61% ethnic minority) and their mothers completed a diagnostic interview and a battery of questionnaires that included self- and mother-ratings of child effortful control, anxiety sensitivity, and anxiety and depressive symptoms. The indirect effect of effortful control via anxiety sensitivity on child anxiety and depressive symptoms was significant across child- and mother-completed measures. Among clinically anxious youth, greater effortful control was related to lower anxiety sensitivity, which was related to lower anxiety and depressive symptoms. Future work should evaluate whether targeting effortful control leads to clinically meaningful reductions in anxiety sensitivity and child anxiety and depressive symptoms.
2022-09-02T13:29:22.404Z
38,261,600
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1583/04-1337R.1", "MAG": "2128767215", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Purpose: To evaluate the effect of oral anticoagulation on durability of endovascular aortic aneurysm repair (EVAR). Methods: Retrospective review was conducted of 182 consecutive EVAR patients (169 men; mean age 75.3 years, range 53–89) between 1999 and 2003. Patients on warfarin anticoagulation (WA, n=21; International Normalized Ratio of 2 to 3) were compared against a control group (CG) with no postoperative anticoagulation (n=161). Death, aneurysm rupture, and reintervention were considered primary endpoints; endoleaks, endograft migration, and aneurysm remodeling were secondary endpoints. Results: Mean follow-up was 16.3±12.6 months. One-year mortality was 6.6% (9.5% WA versus 6.2% CG); overall mortality was 14.3% (p=0.414). No aneurysm rupture occurred. At 1, 2, and 3 years, respectively, cumulative reinterventions (20%/20%/20% WA versus 12%/15%/20% CG; p=0.633) and endoleak rates (25%/25%/25% WA versus 17%/22%/34% CG; p=0.649) were comparable. In both groups, most completion endoleaks resolved (42.9% WA versus 74.4% CG; p=0.474), but few de novo endoleaks did (0% WA versus 12.8% CG; p=0.538). Anticoagulation did not affect mean time to aneurysm sac shrinkage (1.3±0.3 WA versus 1.4±0.1 years CG; p=0.769). Conclusions: After EVAR, anticoagulation appears safe and does not significantly alter mortality, risk for rupture, or the incidence of reintervention. Early endoleaks appear more common in anticoagulated patients, but anticoagulation does not preclude spontaneous endoleak resolution nor does it increase late endoleak rates. Irrespective of the anticoagulation status, early but not late endoleaks usually sealed spontaneously. Observing type II endoleaks appears safe in the absence of aneurysm enlargement.
2022-12-20T06:05:39.802Z
222,232,883
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1101/2020.10.07.330068", "MAG": "3092443568", "PubMedCentral": null }, "license": null, "status": "GREEN", "url": "https://doi.org/10.1016/j.micpath.2021.105041" }
The intrinsically disordered proteins/regions (IDPs/IDPRs) are known to be responsible for multiple cellular processes and are associated with many chronic diseases. In viruses, the existence of disordered proteome is also proven and are related with its conformational dynamics inside the host. The SARS-CoV-2 virus has a large proteome, in which, structure and functions of many proteins are not known as of yet. Previously, we have investigated the dark proteome of SARS-CoV-2. However, the disorder status of non-structural protein 11 (nsp11) was not possible because of very small in size, just 13 amino acid long, and for most of the IDP predictors, the protein size should be at least 30 amino acid long. Also, the structural dynamics and function status of nsp11 was not known. Hence, we have performed extensive experimentation on nsp11. Our results, based on the Circular dichroism spectroscopy gives characteristic disordered spectrum for IDPs. Further, we investigated the conformational behaviour of nsp11 in the presence of membrane mimetic environment, alpha helix inducer, and natural osmolyte. In the presence of negatively charged and neutral liposomes, nsp11 remains disordered. However, with SDS micelle, it adopted an α-helical conformation, suggesting the helical propensity of nsp11. At the end, we again confirmed the IDP behaviour of nsp11 using molecular dynamics simulations.
2023-01-01T06:19:32.041Z
54,204,885
{ "externalids": { "ACL": null, "ArXiv": "1502.02021", "DOI": "10.1103/PhysRevD.92.084064", "MAG": "2127047071", "PubMedCentral": null }, "license": null, "status": null, "url": null }
We have studied the dynamics of an equal-mass magnetized neutron-star binary within a resistive magnetohydrodynamic (RMHD) approach in which the highly conducting stellar interior is matched to an electrovacuum exterior. Because our analysis is aimed at assessing the modifications introduced by resistive effects on the dynamics of the binary after the merger and through to collapse, we have carried out a close comparison with an equivalent simulation performed within the traditional ideal magnetohydrodynamic approximation. We have found that there are many similarities between the two evolutions but also one important difference: the survival time of the hyper massive neutron star increases in a RMHD simulation. This difference is due to a less efficient magnetic-braking mechanism in the resistive regime, in which matter can move across magnetic-field lines, thus reducing the outward transport of angular momentum. Both the RMHD and the ideal magnetohydrodynamic simulations carried here have been performed at higher resolutions and with a different grid structure than those in previous work of ours [L. Rezzolla, B. Giacomazzo, L. Baiotti, J. Granot, C. Kouveliotou, and M. A. Aloy, Astrophys. J. Letters 732, L6 (2011)], but confirm the formation of a low-density funnel with an ordered magnetic field produced by the black hole--torus system. In both regimes the magnetic field is predominantly toroidal in the highly conducting torus and predominantly poloidal in the nearly evacuated funnel. Reconnection processes or neutrino annihilation occurring in the funnel, none of which we model, could potentially increase the internal energy in the funnel and launch a relativistic outflow, which, however, is not produced in these simulations.
2022-12-29T15:40:20.750Z