corpusid
int64 5
255M
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dict | abstract
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16,413,269 |
{
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"DOI": "10.1145/1012807.1012833",
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|
Trails are a well-established concept to assist users in navigating through information spaces. However, most existing trail-based systems focus only on the World Wide Web and not on the users' overall information space, including corporate intranet shares or private file storage. We have adapted the trail approach specifically to fit shared directory scenarios. We describe an already developed prototype and report on results of a first user study, which indicate the usefulness of our approach.
|
2022-09-10T23:12:16.819Z
|
11,431,701 |
{
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"ArXiv": null,
"DOI": "10.3109/10826089409047907",
"MAG": "2128079554",
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|
Some studies have found that sex-related HIV risk behavior is less common among drug users in treatment than among users not in treatment; other studies have found no such relationship. However, past studies have not controlled for drug-user background characteristics that might confound the relationship between treatment and risk behavior. Among this sample of injection drug users in Los Angeles, those enrolled in methadone maintenance treatment report fewer past-year sex partners than those not in treatment; among treatment clients, number of past-year partners is negatively related to time in treatment. These findings persist after age and other background characteristics are controlled. Path analyses suggest that treatment may reduce sex-risk behavior by facilitating clients' disengagement from paid sex and raising their perceived self-efficacy for risk reduction.
|
2022-12-15T03:47:57.501Z
|
2,733,019 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1145/1822018.1822072",
"MAG": "2070527059",
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|
This PhD research aims to understand the influence of consumers' experiences in 3D virtual worlds on their perceptions and expectations of 2D e-commerce websites. Interviews are being conducted with consumers who have shopping experiences in 3D and 2D environments. The contribution of this research will be an understanding of user needs in e-commerce environments. This understanding will be applied to develop e-commerce design guidelines in both 2D and 3D e-commerce environments.
|
2022-12-20T01:28:19.082Z
|
152,534,773 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/14631379408427805",
"MAG": "1501141388",
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},
"license": null,
"status": "GREEN",
"url": "http://www-wds.worldbank.org/external/default/WDSContentServer/WDSP/IB/1994/03/01/000009265_3961006031252/Rendered/PDF/multi_page.pdf"
}
|
Meeting government revenue needs without inhibiting private sector development is a key challenge of tax policy during the transition from the socialist system. The paper explores issues in the design of tax bases and tax structures in the transition and argues that transition economies would need to adopt a lower and simpler tax structure than the ones prevailing in developed Western market economies.
|
2022-09-10T15:15:06.030Z
|
141,206,199 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1176/AJP.144.9.1220",
"MAG": "166339959",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
: Cases of profound hypoglycemia after the initiation of tricyclic antidepressant therapy in two patients taking sulfonylureas are described. To the authors' knowledge, this is the first report of a potential drug interaction between tricyclic antidepressants and sulfonylureas.
|
2022-09-15T08:22:52.126Z
|
28,056,949 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CARPATHIANCC.2015.7145148",
"MAG": "1565759273",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
With the implementation of the principle of the Internet of Things raises demands for new services as well as technical requirements that enable their implementation. One of the fields is the localization of wounded in mass disasters. Currently, the identification is performed by paper / plastic triage tags, which are used to label wounded victim at first contact with rescue unit based on the state of the causality. Automatic identification using active RFID technology is in such a case a solution which permits remote technically sophisticated surveillance of the situation. It is advantageous to use active RFID tags as a low-power transmitter, which is an immense advantage comparison with GPS technology. Lifetime of such tag can be several months. Managed active RFID tags can localize wounded objects within the range of a few hundred meters in free space and indicate the degree of severity of the injury of individual causalities. RFID readers, i.e. locators placed in that area, evaluate the direction of arrival of each tag and transmit obtained information to the computer system, which calculates the position of each RFID tag using sophisticated signal processing methods. This information can be displayed in a specific map including classification of tags, their movement or history. This paper focuses on the testing and experimental verification of such a system. The results of the experiment verify the concept of an RFID locator with achieved accuracy of 2.1 m in the area of 100 × 100 m.
|
2022-10-27T19:29:53.788Z
|
21,573,341 |
{
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"ArXiv": null,
"DOI": "10.1111/j.1365-2826.2011.02111.x",
"MAG": "1835666637",
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|
Peptide YY (PYY) and pancreatic polypeptide (PP) are two appetite suppressing hormones, released post‐prandially from the ileum and pancreas, respectively. PYY3‐36, the major circulating form of the peptide, is considered to reduce food intake in humans and rodents via high affinity binding to the auto‐inhibitory neuropeptide Y receptor Y2R, whereas PP is considered to act through the Y4R. Current evidence indicates the anorexigenic effects of both peptides occur via signalling in the brainstem and arcuate nucleus (ARC) of the hypothalamus. Manganese‐enhanced magnetic resonance imaging (MEMRI) has previously been used to track hypothalamic neuronal activity in vivo in response to both nutritional interventions and gut hormone treatment. In the present study, we used MEMRI to demonstrate that s.c. administration of PP results in a significant reduction in signal intensity (SI) in the ARC, ventromedial hypothalamus and paraventricular nucleus of fasted mice. Subcutaneous delivery of PYY3‐36 resulted in a nonsignificant trend towards decreased SI in the hypothalamus of fasted mice. We found no SI change in the area postrema of the brainstem after s.c. injection of either peptide. These differences in hypothalamic SI profile between PP and PYY3‐36 occurred despite both peptides producing a comparable reduction in food intake. These results suggest that separate central pathways control the anorexigenic response for PP and PYY3‐36, possibly via a differential effect of Y4 receptor versus Y2 receptor signalling. In addition, we performed a series of MEMRI scans at 0–2, 2–4 and 4–6 h post‐injection of PYY3‐36 and a potent analogue of the peptide; PYY3‐36 (LT). We recorded a significant reduction in the ARC SI 2–4 h after PYY3‐36 (LT) injection compared to both saline and PYY3‐36 in fasted mice. The physiological differences between PYY3‐36 and its analogue were also observed in the long‐term effects on food intake, with PYY3‐36 (LT) producing a more sustained anorexigenic effect. These data suggest that MEMRI can be used to investigate the long‐term effects of gut peptide delivery on activity within the hypothalamus and brainstem.
|
2022-10-03T16:31:41.537Z
|
144,781,208 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5642/STEAM.201301.06",
"MAG": "2070291961",
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},
"license": null,
"status": null,
"url": null
}
|
STEM and STEAM are in the news. Researchers and educators in my field (cognition, art, and creativity) argue reasons for adding the A to STEM. While I visit this below, my focus is elsewhere. In this brief essay, I want to explore the meaning and importance of the E appearing in both STEM and STEAM. What’s engineering doing in this mix? And what are some reasons for affirming the arts when the role of engineering is clarified? Author/Artist Bio Dr. James S. Catterall is Professor Emeritus and past Chair of the Faculty at the UCLA Graduate School of Education and Information Studies. Dr. Catterall is an Affiliate Faculty member at the UCLA Center for Culture, Brain, and Development. Dr. Catterall is also the Principal Investigator at the Centers for Research on Creativity, (CRoC), based in Los Angeles and London, UK. (www.croc-lab.org). Dr. Catterall is coauthor of “Critical Links: Learning in the Arts and Student Academic and Social Development,” Arts Education Partnership’s (AEP) 2002 landmark compilation, which provides summaries of numerous significant research studies in dance, drama, the multi-arts, music and visual arts as well as comprehensive summaries written by some of the most recognized names in arts research.
|
2022-12-02T11:32:31.055Z
|
15,504,279 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1109/HIS.2009.268",
"MAG": "2146562961",
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"license": null,
"status": null,
"url": null
}
|
For discovering communities in social network, an improved spectral clustering method is presented in this paper. To make full use of the network feature, the core members are used in this method for mining communities. This goal has been achieved through the Page Rank method, which is common in directed graphs, for the reason that an undirected graph can be treated as the special case of the corresponding directed one. Following that, they can be used for initialization in the spectral clustering to avoid the sensitivity to the initial centroids. Applied to four datasets, the improved method turns out to be better than the traditional spectral clustering methods, whether in time or in accuracy aspect.
|
2022-12-17T09:35:45.004Z
|
89,948,086 |
{
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"ArXiv": null,
"DOI": "10.1080/0005772X.2016.1215226",
"MAG": "2562999435",
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"status": null,
"url": null
}
|
Concerns have been raised that invertebrate pollinators of crops and wild plants are in decline as a result of modern agricultural practices, habitat degradation, and introduced pests and diseases. This impending global pollinator crisis demands a response from land managers, conservationists, and political decision-makers. Until very recently, most farmers considered pollination one of nature’s many “free services.” Pollination is so taken for granted that it has rarely figured as an “agricultural input” or included as a subject in agricultural science courses.
|
2022-02-10T19:20:04.910Z
|
108,727,977 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CLEOE.1994.636553",
"MAG": "1588478440",
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"license": null,
"status": null,
"url": null
}
|
This PNLS is identical with the same equation, in the case of homogeneously broadened line5 under the condition Y' = 0. Consequently, we can conclude that in the case of nonsymmetrical broadening, g(A) f g(-A), or for ultrashort pulses, duration 7" 5 TD the effect of the inhomogeneously broadened line could have a strong influence on the amplification dynamics of the soliton-like pulses. The magnitude of this influence is in the first order by parameter y. These analytical results are based on the restricting assumption of the smallness of the parameters (yzz, p), and therefore for pulses shorter than 1 ps, we verified them by comparison with numerical experiments, obtaining a good correspondence between the theoretical prediction and the results are given by the simulations. *Permanent Address: Facultad de Ciencias Fisico-Matematicas, Benemkrita Universidad Aut6noma de Puebla, Mexico
|
2022-02-10T06:48:30.478Z
|
18,115,888 |
{
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"ArXiv": null,
"DOI": "10.7282/T3XK8DC8",
"MAG": "2282025017",
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"status": null,
"url": null
}
|
Planar cell polarity (PCP) is known as the polarization of cells within the plane of the tissue layer. This form of polarization controls several epithelial and non-epithelial morphological processes, such as the orientation of primary cilia in the inner ear, convergent extension (CE) and directed migration. A three tiered model of PCP regulation has been proposed which consists of the global, core, and effector modules. However there is one addition level of modulation through non-canonical Wnt signaling pathway. Of the many Wnt proteins a few have been identified to signal primarily through this pathway. One such protein is Wnt5a, which has been shown to modulate PCP during directed cell migration. In this study we gather preliminary data for the presence of PCP signaling components in Schwann cells and investigate the effect of Wnt5a and its antagonist Wnt3a on Schwann cell proliferation, migration and myelination.
|
2022-07-27T06:42:05.728Z
|
2,795,273 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1111/j.1464-5491.1986.tb00726.x",
"MAG": "1992374727",
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}
|
The frequency and distribution of daytime biochemical hypoglycaemia (capillary blood glucose concentration below 3 mmol/l) was assessed in type 1 diabetic patients on conventional twice daily insulin therapy (n = 79) and on continuous subcutaneous insulin infusion (n = 20). Patients collected and mailed to the hospital blood for seven‐point blood glucose profiles. For both treatment regimens the frequency of biochemical hypoglycaemia on individual days was inversely related to the median blood glucose concentration in a curvilinear manner (p < 0.001). Hypoglycaemia was more frequent pre‐prandially than post‐prandially (p < 0.01), and was evenly distributed during the day in patients on continuous subcutaneous insulin infusion. In patients on conventional therapy, however, pre‐lunch hypoglycaemia was four times more frequent than pre‐breakfast or pre‐dinner hypoglycaemia (p < 0.0001).
|
2022-08-31T18:40:41.971Z
|
143,531,962 |
{
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"ArXiv": null,
"DOI": "10.1080/00049539908255343",
"MAG": "1982090629",
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}
|
Arising from the growing need for a comprehensive career-guidance service for adults, and in particular for unemployed people in Australia, this study reports results that can be interpreted as generally supporting the use of the VISA with the unemployed. Additionally, the factor analyses, particularly the higher order factor analysis, raised questions about the utility of the eight VISA subscales and suggested that a two-factor solution of the VISA data might be more practical for practitioners providing vocational counselling to the unemployed. Descriptive statistics for the unemployed Australian population suggest that if a two-factor solution is used to Interpret the data, then the unemployed are significantly more likely to nominate their interests toward the things pole of a people–things dimension than Australian secondary school students. The study begins to address the dearth of research in the area of career guidance for the unemployed.
|
2022-09-01T22:23:27.745Z
|
168,652,674 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1177/0019466220110309",
"MAG": "2735544696",
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"license": null,
"status": null,
"url": null
}
|
By inclusive growth we mean that growth process which benefits all sections, all sectors and all regions of the economy, though not uniformly. It is broad-based growth. How inclusive growth can be achieved in India is a very complex issue, depending upon a variety of factorsthe most important being financial inclusion. If the financial sector is to contribute more to inclusive growth, it must reach out to more people. In this context policy approaches like micro finance has emerged as the most effective tool for promoting faster and more inclusive growth and helps in reducing poverty by providing a regular source of livelihood in a significant manner. The micro finance sector in India is at the threshold of massive expansion. There is a need to strength all the existing mechanisms of micro credit delivery such as the self-help group (SHG)-bank linkage programme, the primary agriculture cooperative societies (PACs), the micro finance institutions (MFIs) and also bringing in new agencies such as the post-offices to the micro finance sector. However, the SHG-bank linkage programme is a potent initiative for delivering financial services to the poor in a sustainable manner. The main objective of the present study is to analyse and review the SHG-bank linkage programme in the state of Madhya Pradesh (MP) which is one of the 13 identified priority states which account for about 70 per cent of the rural poor population.
|
2022-12-10T02:01:17.615Z
|
202,365,582 |
{
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"ArXiv": null,
"DOI": "10.1080/02650487.2019.1652526",
"MAG": "2967926789",
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"license": null,
"status": null,
"url": null
}
|
Abstract This paper provides an overview of the complexity of humour. It also provides an introduction to the Special Issue on the use of humour in advertising.
|
2022-12-19T11:16:29.773Z
|
119,300,963 |
{
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"ACL": null,
"ArXiv": "1802.05527",
"DOI": "10.1137/18M1174787",
"MAG": "2963815847",
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"license": null,
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}
|
By a memory mean-field stochastic differential equation (MMSDE) we mean a stochastic differential equation (SDE) where the coefficients depend on not just the current state $X(t)$ at time $t$, but also on previous values (history/memory) $X_{t}:=\{X(t-s)\}_{s\in\lbrack0,\delta]}$, as well as the law $M(t):=\mathcal{L}(X(t))$ and its history/memory $M_{t}=\{M(t-s)\}_{s\in \lbrack0,\delta]}$.
Similarly, we call the equation (time-)advanced and abbreviate it to AMSDE if we in the above replace $X_{t}$ by the forward segment $X^{t}:=\{X(t+s)\}_{s\in\lbrack0,\delta]}$ and replace $M_{t}$ by $M^{t}:=\{M(t+s)\}_{s\in\lbrack0,\delta]}.$
In the same way we define the reflected advanced mean-field backward} SDE (AMBSDE).
We study the following topics:
- We prove the existence and uniqueness of the solutions of some reflected AMBSDEs,
- we give sufficient and necessary conditions for an optimal singular control of an MMSDE with partial information, and
- we deduce a relation between the optimal singular control of a MMSDE, and the optimal stopping of such processes.
|
2022-12-23T02:01:02.522Z
|
146,836,797 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.26668/indexlawjournals/2358-1352/2013.v5i3.2728",
"MAG": "2301441206",
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},
"license": null,
"status": "GOLD",
"url": "http://www.indexlaw.org/index.php/rdb/article/download/2728/2618"
}
|
O pos-guerra gerou profundas alteracoes no contexto internacional, sendo relevante destacar a alta mobilidade do capital e a transnacionalizacao das empresas, o que determinou a necessidade de atuacao conjunta entre os paises, tanto para evitar a dupla tributacao do capital quanto a evasao tributaria. Nesse contexto, ganhou importância o trabalho desenvolvido pela OCDE, que editou Modelo
de Convencao Contra Dupla Tributacao da Renda e do Capital. Por sua vez, no intuito de evitar a utilizacao de paises de tributacao favorecida ou de paraisos fiscais como forma de nao pagamento de tributos, surgiram, no contexto internacional, as legislacoes sobre transparencia fiscal. Diante desse cenario, o presente artigo buscara analisar a legislacao brasileira sobre transparencia fiscal, em contraposicao ao Modelo de Convencao Contra Dupla Tributacao da OCDE.
DOI: 10.5585/rdb.v5i3.104
|
2022-08-20T11:16:49.873Z
|
123,325,119 |
{
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"ArXiv": null,
"DOI": "10.1515/jnetdy.2010.020",
"MAG": "2170825948",
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},
"license": null,
"status": null,
"url": null
}
|
Abstract The behavior of entropy of a model isolated system in which there is non-classical heat conduction is considered. Within the thermodynamic formalism developed, expressions are obtained for the entropy flux and source and also for the total entropy of the isolated system. The approach proposed leads to a strictly monotonic dependence of the total entropy on time for the model system considered.
|
2022-09-08T03:49:59.919Z
|
28,710,756 |
{
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"ArXiv": null,
"DOI": "10.1177/1932296816677296",
"MAG": "2550560345",
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},
"license": null,
"status": "BRONZE",
"url": "https://journals.sagepub.com/doi/pdf/10.1177/1932296816677296"
}
|
Safety and efficacy of a nurse-directed electronic glycemic management system (eGMS) in comparison to basal-bolus subcutaneous insulin therapy managed by providers has been evaluated recently by Aloi et al. They included 993 non–critically ill patients across 9 different hospitals in a retrospective observational crossover study and compared mean blood glucose, number of hypoglycemic events <40 mg/dl and <70 mg/dl and the percentage of blood glucose in target (140-180 mg/dl) before, during and after the use of eGMS. Conclusion was that eGMS can lead to better glycemic control with less hypoglycemic events compared to provider managed basal-bolus insulin therapy (before and after eGMS). Although some limitations exist, the authors made a strong case that eGMS has positive impact on glycemic control in hospitalized patients with diabetes.
|
2022-12-11T00:18:31.141Z
|
88,630,543 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1590/1809-43921992224539",
"MAG": "2418608847",
"PubMedCentral": null
},
"license": "CCBYNC",
"status": "GOLD",
"url": "http://www.scielo.br/pdf/aa/v22n4/1809-4392-aa-22-4-0535.pdf"
}
|
Sixtheen species of bryophytes are reported for Maraca Island, State of Roraima, Brazil. Of these total, nine species are new recorde for Roraima State.
|
2022-12-18T08:27:29.018Z
|
229,040,166 |
{
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"ArXiv": null,
"DOI": "10.5194/epsc2020-1034",
"MAG": "3099971329",
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"license": null,
"status": null,
"url": null
}
|
<p>(596) Scheila was observed to have an active appearance as a result of impact event in late 2010. In additional the coma feature, the shape of light curve had been found the difference probably fresh material or surface properties changed around the impact site. In this study, we present the results of our monitoring observations obtained in 2014 and 2019-2020. The mean values of the color indices (B−V = (0.75 ± 0.08)<sup>m</sup>, V−R = (0.45 ± 0.04)<sup>m</sup>, and R−I = (0.44 ± 0.09)<sup>m</sup>) agree well with the values for asteroids of the D-types. The rotation period of the asteroid estimated from photometric observations in 2014 is 15.8 ± 0.1 h. The shape of the light curve is similar as that found after impact event. Furthermore, we did not find any rotational color variability in B-V, V-R and R-I diagrams, meaning the observed surface in this observing period of 2019-2020 is homogeneous.</p>
|
2022-01-27T01:48:21.194Z
|
154,522,270 |
{
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"ArXiv": null,
"DOI": "10.1080/09700160108455333",
"MAG": "2056445640",
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"license": null,
"status": null,
"url": null
}
|
Abstract The article deals with the long‐standing requirement for restructuring the Ministry of Defence (MoD). Supremacy of civil over military authority in its application to the Indian context has come to mean bureaucratic prevalence at the uppermost level in virtually all defence related decision‐making. This antiquated mechanism is in need of replacement by another where uniformed personnel have a greater say as participants in an integrated MoD. The Arun Singh Committee recommendations on the issue have remained unimplemented for over a decade. India remains one of the very few democratic countries where generalists hold sway over generals and all attempts to change the system are repeatedly thwarted. The time is perhaps ripe when a Joint Chiefs of Staff, or some other alternative system such as exist in other major democracies was instituted. The operational, financial and manpower benefits are too many to ignore this demand any further.
|
2022-02-09T01:47:43.292Z
|
223,836,470 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.35693/2500-1388-2018-0-4-68-72",
"MAG": "3029868895",
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},
"license": "CCBY",
"status": "HYBRID",
"url": "https://journals.eco-vector.com/2500-1388/article/download/21418/17659"
}
|
Objectives - to make an assessment of the actual situation in the population ageing process and to define its tendency. Material and methods. The classification characteristics are defined based on the calculation on the elderly people ratio to the total number of people. The structure of the international ranking is presented. The modern approach such as a prospective age was the basis of the ageing evaluation. The point of analysis was the ageing tendency in the Samara region population in the 20th century, observing its range and structure marks, the degree according to the ageing index. Results. The prognostic ageing values of the 2010 year for the period till 2031were corrected. The escalation of the eldest population group in the nearest future was decisively proved. The further interdisciplinary problem management was stated to be focused on, as the elderly people are crucially dependent on the just-in-time and full-range healthcare services supported by the social adaptation.
|
2022-05-13T17:47:27.403Z
|
244,409,724 |
{
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"ArXiv": null,
"DOI": "10.15446/revfacmed.v70n4.93048",
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"PubMedCentral": null
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"license": "CCBY",
"status": "GOLD",
"url": "https://revistas.unal.edu.co/index.php/revfacmed/article/download/93048/81307"
}
|
Introducción. La acidosis metabólica es una condición fisiopatológica frecuente en pacientes críticos. Esta alteración es evaluada mediante diferentes variables fisiológicas; sin embargo, su valor pronóstico aún no está bien definido.
Objetivo. Evaluar la asociación entre variables del componente metabólico del estado ácido base (EAB) y mortalidad a 28 días en pacientes de una unidad de cuidados intensivos (UCI) en Bogotá D.C., Colombia.
Materiales y métodos. Estudio de cohorte prospectivo realizado en 122 pacientes hospitalizados en una UCI entre enero y junio de 2013 y con una estancia mayor a 24 horas. Se tomaron muestras sanguíneas y gases arteriales de ingreso para el cálculo de las siguientes variables: Anion Gap (AG), Anion Gap corregido (AGc), Base exceso estándar (BEst), H+ metabólicos, Base exceso-aniones no medibles (BEua), pH, lactato, HCO3-st, Brecha de iones fuertes (BIF), puntaje Apache II, y puntaje SOFA. Se realizó un análisis bivariado, calculándose OR con un nivel de significancia de p<0.05, y luego uno multivariado, mediante un modelo de regresión logística, para identificar las variables asociadas con la mortalidad a 28 días.
Resultados. De los 122 pacientes, 33 (27.7%) fallecieron a 28 días y 51 (48.7%) eran mujeres. La edad promedio fue 46.5 años (±15.7). En el análisis bivariado, las siguientes variables se asociaron significativamente con la mortalidad a 28 días: BIF: OR=1.150 (p=0.008), BEua: OR=0,897 (p=0.023), AG: OR=1.231 (p=0.002), AGc: OR=1.232, (p=0.003), pH arterial: OR=0.001, (p=0.023), APACHE II: OR=1.180 (p=0.001), HCO3- st: OR=0.841 (p=0.015). En el análisis multivariado, solo el puntaje APACHE II se asoció significativamente con la mortalidad a 28 días: OR=1.188 (p=0.008).
Conclusión. Las variables fisiológicas que evalúan el componente metabólico del estado ácido-base, tanto las del modelo de Henderson, como las del modelo de Stewart, no se asociaron significativamente con la mortalidad a 28 días en la población de estudio.
|
2022-01-27T02:03:45.896Z
|
121,281,583 |
{
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"ArXiv": null,
"DOI": "10.1088/1674-1056/21/8/086101",
"MAG": "2061964596",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Mechanical properties of silicon nanobeams are of prime importance in nanoelectromechanical system applications. A numerical experimental method of determining resonant frequencies and Young's modulus of nanobeams by combining finite element analysis and frequency response tests based on an electrostatic excitation and visual detection by using a laser Doppler vibrometer is presented in this paper. Silicon nanobeam test structures are fabricated from silicon-on-insulator wafers by using a standard lithography and anisotropic wet etching release process, which inevitably generates the undercut of the nanobeam clamping. In conjunction with three-dimensional finite element numerical simulations incorporating the geometric undercut, dynamic resonance tests reveal that the undercut significantly reduces resonant frequencies of nanobeams due to the fact that it effectively increases the nanobeam length by a correct value ΔL, which is a key parameter that is correlated with deviations in the resonant frequencies predicted from the ideal Euler—Bernoulli beam theory and experimentally measured data. By using a least-square fit expression including ΔL, we finally extract Young's modulus from the measured resonance frequency versus effective length dependency and find that Young's modulus of a silicon nanobeam with 200-nm thickness is close to that of bulk silicon. This result supports that the finite size effect due to the surface effect does not play a role in the mechanical elastic behaviour of silicon nanobeams with thickness larger than 200 nm.
|
2022-09-01T06:12:12.795Z
|
13,073,482 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1749-6632.1975.tb19144.x",
"MAG": "2023116129",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The level of serum albumin has often been relied upon t o reflect the status of the liver in health and disease. It is well known that, while the concentration of serum albumin is decreased in alcohol-induced cirrhosis, data are available indicating that in many cases the exchangeable albumin pool is not depressed;’ further, when alcohol is removed and adequate nutrition supplied, the albuminsynthesizing potential is restored.* The question whether the removal of alcohol or the institution of adequate nutrition was responsible for the liver’s recovery has been the subject of much debate. In vivo the level of albumin is the net result of synthesis, degradation, and distribution, and in the whole animal albumin synthesis is influenced by the interplay of the nutritional status of the animal, e n ~ i r o n m e n t , ~ hormones, oncotic equilibrium,“ and toxins, as well as the state of health. Thus, in vivo, it is difficult t o study the effect of one isolated factor in albumin synthesis, and for this reason the isolated perfused liver was employed. The advantages are obvious: (a) the perfusion medium can be altered in a particular manner with any substance with the knowledge that the substance perfusing the liver has not been altered by prior passage through any tissue: (b) the effects of pretreatment of the inact animal on the liver’s ability to synthesize albumin can be studied by removal of the liver after pretreatment; and (c) subcellular systems can be isolated following perfusion and correlative evidence of altered microstructure with altered liver function may be obtained. In the present study the isolated perfused liver was used t o study the effects of altered nutrition, in the absence and presence of ethyl alcohol, on the liver’s ability t o synthesize albumin as well as the correlative effect on the endoplasmic reticulum-bound polysome, the organelle responsible for the synthesis of albumin. The results indicated that a short term fast of 24 hours was sufficient t o decrease albumin synthesis to one-half that found in livers from fed donors. The decrease in albumin synthesis was coincident with a disaggregation of the bound polysome. However, this effect could be readily reversed by the presence
|
2022-09-06T08:40:26.565Z
|
252,025,999 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/su141710859",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2071-1050/14/17/10859/pdf?version=1662478606"
}
|
Recent research indicates that the coronavirus disease 2019 (COVID-19) pandemic has impacted road traffic operation quality. From the perspective of service level, safety level, and operation orderliness, this study attempts to analyze the limited responses of the operation quality of the provincial expressway network (PEN) to the impact of COVID-19. The traffic operation data of the PEN in Shaanxi Province were collected for three consecutive years (from 2019 to 2021) before and after the COVID-19 outbreak, including weekly average daily traffic, weekly traffic interruption times, weekly traffic control time, weekly traffic accidents, weekly traffic injuries, and weekly traffic deaths. Through descriptive statistics and dynamic analysis, we studied the limited responses of the safety and service levels of the PEN to the impact of COVID-19. An evaluation model of operation orderliness of the PEN was established by using dissipative structure theory and entropy theory. Results show that in 2020, the service level, safety level, and operation orderliness of the PEN dropped to their lowest. With the gradual control of pandemic, its negative impacts on the service level and operation orderliness of the PEN gradually decreased but did not recover to the pre-pandemic level. In terms of the safety level, the number of traffic accidents, traffic injuries, and traffic deaths decreased, whereas the traffic accident rate and accident casualty rate remained high. In summary, the operation quality of the PEN in Shaanxi Province has had a limited response to the impact of COVID-19.
|
2022-12-02T11:51:24.546Z
|
1,020,603 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4103/0972-5229.178182",
"MAG": "2299199518",
"PubMedCentral": "4810896"
},
"license": "CCBYNCSA",
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc4810896"
}
|
Hypocalcemia is a frequent finding in acute pancreatitis. Severe hypocalcemia can present with neurological as well as cardiovascular manifestations. Correction of hypocalcemia by parenteral calcium infusion remains a controversial topic as intracellular calcium overload is the central mechanism of acinar cell injury in pancreatitis. The current article deals with the art and science of calcium correction in pancreatitis patients.
|
2022-12-04T00:16:49.598Z
|
149,621,909 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S0963926818000536",
"MAG": "2897484965",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
ABSTRACT This article examines the thriving lodging house sector in early modern Venice, arguing that such spaces of temporary accommodation offer a valuable key to understanding how mobility and migration shaped the daily lived experience of the city. Lodging houses were important both to the many Venetian residents who profited from renting out rooms, and to the people who stayed in them, and found there companionship, conversation and access to social and professional networks. Considering the kinds of encounters, conflicts and exchanges that unfolded in these shared spaces, the article offers new insight into the functioning of a pre-modern multicultural metropolis.
|
2022-11-27T22:48:39.803Z
|
96,068,293 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1080/01496399608001064",
"MAG": "2000780103",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract The effect of plate spacing on the degree of separation and production rate for the enrichment of heavy water in flat-plate thermal diffusion columns of the Frazier scheme with fixed operating expense has been investigated. The equations for estimating optimum plate-spacing for maximum separation and for maximum production rate have been developed. Considerable improvement in performance is obtainable when thermal diffusion columns with optimum plate-spacing are employed for operation.
|
2022-02-10T14:45:57.368Z
|
97,445,794 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1139/CJC-77-1-28",
"MAG": "2068084179",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In previous work we introduced an abstract space of bond critical point properties, called BCP space, to measure the similarity between molecules. In this contribution we critically examine the dependence of properties in BCP space on equilibrium bond length, a topic which has been extensively investigated in the literature. For that purpose we have designed a data set of 57 molecules yielding 731 bond critical points. We confirm the existence of local linear relationships provided the bonds vary little in their chemical surroundings. Such relationships break down completely for larger subsets of bond critical points encompassing a wider variety of bonds. The patterns observed in the global picture show so little correlation that one may safely conclude that BCP properties cannot be trivially recovered or even predicted by knowledge of bond length alone.
|
2022-12-14T23:50:57.580Z
|
239,635,022 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3895/ACTIO.V6N2.14525",
"MAG": "3197194854",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A divulgação científica é um termo destinado para definir a interação comunicacional entre ciência e público. Ela pode-se dar de várias maneiras, entre elas através da arte. O teatro científico é uma expressão artística capaz de promover a divulgação científica por meio das artes cênicas, neste tipo de teatro o conhecimento científico é o foco central das peças teatrais. Diante disso, este trabalho traz os resultados de uma pesquisa exploratória que buscou mapear as temáticas presentes nas peças teatrais apresentadas nas treze edições do evento Ciência em Cena para identificar as tendências de divulgação científica promovidas pelo evento em sua trajetória por diferentes regiões do país. Os dados foram coletados a partir de buscadores na internet e constituíram-se de apresentações vídeo-gravadas e sinopses das 137 peças que compõem o conjunto de todas as edições do evento. Fizemos a catalogação do evento por estado e região, peças apresentadas, grupos teatrais participantes, suas origens regionais e institucionais. Em seguida, identificamos a área científica de vinculação prioritária (Biologia, Física, Matemática, Química, Ciências ou outras), depois analisamos a temática central que sustenta o enredo de cada peça. A partir da lista de temáticas procedemos à sua categorização em categorias emergentes. Foram identificadas 10 categorias nas peças: Ciência no cotidiano, Conhecimentos da Biologia, Conhecimentos da Física, Conhecimentos da Química, Conhecimentos da Matemática, História da ciência, Fazer da ciência e do cientista, Questões ambientais, Utilização de experimentos e Outros. Os resultados apontaram que a maior parte das peças é proveniente da área da Química, assim como muitos grupos têm origem em cursos dessa área. O evento circulou majoritariamente pelas regiões sudeste e nordeste, com apenas uma edição na região sul e nenhuma edição nas regiões centro-oeste e norte do país e já recebeu 44 grupos teatrais distintos, provenientes das regiões em que o evento ocorreu e de países como Portugal e Espanha. Em relação às temáticas divulgadas aos espectadores, identificamos a recorrência do fazer da ciência e do cientista ao longo de todo o evento, a história da ciência foi muito presente até 2015 quando decaem bastante as peças que abordam essa temática, na região nordeste nota-se a circulação forte de peças envolvendo o uso de experimentos, na região sudeste foram bastante divulgadas peças envolvendo conhecimentos da área da física. O número de peças que abordam temáticas fora das ciências exatas e naturais é muito pequeno.
|
2022-12-20T03:42:07.442Z
|
235,248,221 |
{
"externalids": {
"ACL": null,
"ArXiv": "2105.13649",
"DOI": "10.34727/2021/isbn.978-3-85448-046-4_27",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Deep neural networks (DNNs) play an increasingly important role in various computer systems. In order to create these networks, engineers typically specify a desired topology, and then use an automated training algorithm to select the network’s weights. While training algorithms have been studied extensively and are well understood, the selection of topology remains a form of art, and can often result in networks that are unnecessarily large — and consequently are incompatible with end devices that have limited memory, battery or computational power. Here, we propose to address this challenge by harnessing recent advances in DNN verification. We present a framework and a methodology for discovering redundancies in DNNs — i.e., for finding neurons that are not needed, and can be removed in order to reduce the size of the DNN. By using sound verification techniques, we can formally guarantee that our simplified network is equivalent to the original, either completely, or up to a prescribed tolerance. Further, we show how to combine our technique with slicing, which results in a family of very small DNNs, which are together equivalent to the original. Our approach can produce DNNs that are significantly smaller than the original, rendering them suitable for deployment on additional kinds of systems, and even more amenable to subsequent formal verification. We provide a proof-of-concept implementation of our approach, and use it to evaluate our techniques on several real-world DNNs.
|
2022-12-19T03:12:59.372Z
|
210,069,337 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.6517/MCUT2015.DEC-08",
"MAG": "2471340990",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
It seems that ＂Fan Chi Qing Xue Jia,＂ a chapter from Confucian Analects, is easy to understand. However, this chapter is often misinterpreted. Literally, it reads like Confucius denied the importance of agriculture but, as a matter of fact, Confucius never downgraded the role of agriculture. Ancient China was an agricultural society where officials must encourage agricultural production and it is thus reasonable that Fan Chi wanted to gain agricultural knowledge. Confucius did not deny Fan Chi's request but he blamed Fan Chi for his small scope of vision. Confucius believed that officials should not only pay attention to agriculture but also care for the people. Confucius rebuked Fan Chi for not noticing that. Generally speaking, this chapter shows the difference between Confucianism and traditional political theories.
|
2022-01-27T08:24:24.653Z
|
196,852,426 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/HLCA.200900107",
"MAG": "2949411473",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A novel construction of 2-benzazepine derivatives based on TiCl4-mediated tandem Mannich reaction of electron-rich benzyl iminium ions with alkenyl ethers and Friedel–Crafts-type alkylation is described. The protocol is amenable to provide the tricyclic furo[3,2-d][2]benzazepine and pyrano[3,2-d][2]benzazepine derivatives, respectively, with 2,3-dihydrofuran or 3,4-dihydro-2H-pyran as the substrates.
|
2022-02-08T06:52:50.452Z
|
44,533,232 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/ietfec/e88-a.10.2896",
"MAG": "2029704578",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We introduce a differential space-time block code (DSTBC) integrated with trellis coded modulation with two transmit antennas. Our scheme enables transmission of DSTBC encoded symbols as trellis metric rather than concatenating an outer code. Unlike conventional DSTBC, different transmit symbol phase rotations are used for each transmit antenna in order to obtain more options for trellis branch. The set partitioning for proposed codes is derived as well. The decoder computes decision statistic using Viterbi Algorithm with different number of states undergoing Rayleigh fading channels. This approach can provide full diversity gain as well as coding gain simultaneously remaining full transmit rate, which cannot be obtained by conventional DSTBC.
|
2022-02-12T01:17:21.973Z
|
129,346,737 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2172/889817",
"MAG": "1586357844",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://digital.library.unt.edu/ark:/67531/metadc884886/m2/1/high_res_d/889817.pdf"
}
|
The goal of the project was to determine midlatitude climate predictability associated with tropical-extratropical interactions on interannual-to-interdecadal time scales. Our strategy was to develop and test a hierarchy of climate models, bringing together large GCM-based climate models with simple fluid-dynamical coupled ocean-ice-atmosphere models, through the use of advanced probabilistic network (PN) models. PN models were used to develop a new diagnostic methodology for analyzing coupled ocean-atmosphere interactions in large climate simulations made with the NCAR Parallel Climate Model (PCM), and to make these tools user-friendly and available to other researchers. We focused on interactions between the tropics and extratropics through atmospheric teleconnections (the Hadley cell, Rossby waves and nonlinear circulation regimes) over both the North Atlantic and North Pacific, and the ocean’s thermohaline circulation (THC) in the Atlantic. We tested the hypothesis that variations in the strength of the THC alter sea surface temperatures in the tropical Atlantic, and that the latter influence the atmosphere in high latitudes through an atmospheric teleconnection, feeding back onto the THC. The PN model framework was used to mediate between the understanding gained with simplified primitive equations models and multi-century simulations made with the PCM. The project team is interdisciplinary and built on anmore » existing synergy between atmospheric and ocean scientists at UCLA, computer scientists at UCI, and climate researchers at the IRI.« less
|
2022-07-31T04:41:48.805Z
|
15,533,473 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/MA00122A033",
"MAG": "2036814165",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The effect of polystyrene (PS) matrix relaxation on interdiffusion at a PS and poly(vinyl methyl ether) (PVME) interface was investigated with attenuated total internal reflectance infrared spectroscopy (ATR-FTIR) at 105 and 85 °C, corresponding to 5 °C above and 15 °C below the T g of PS, respectively. Monodisperse PS samples with M w of 3.0 x 10 6 and 1.05 x 10 5 were used to simulate relaxation in the PS matrix corresponding to chain reptation and constrained-release mechanisms, respectively. A binary blend of monodisperse PS samples consisting of short chains with M w of 3.0 x 10 4 and long chains with M w of 3.0 x 10 6 was used to simulate relaxation in the PS matrix by tube dilation. In the binary PS blend, the short chains were deuterated in order to monitor the concentration of each component independently. Non-Fickian diffusion was observed above and below the T g of the PS matrix. Above the T g of PS, interdiffusion was enhanced as the matrix relaxation mechanism changed from chain reptation to tube dilation to constrained release, consistent with the predicted relaxation time of these matrices. Below the T g of PS, interdiffusion was controlled by the rate of swelling of PS by PVME and interdiffusion was faster in the binary PS blend due to the reduced entanglement density between the long chains.
|
2022-08-27T05:26:46.629Z
|
67,761,151 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1669/0883-1351(2000)015<0225:HEOIAT>2.0.CO;2",
"MAG": "2054520356",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract The coral reef in Tutum Bay, Ambitle Island, Papua New Guinea, is exposed to the vigorous discharge of hydrothermal fluids (up to 98°C). This study investigates eight Porites lobata samples that were collected throughout the area of active venting at varying distances from vent sites. A sample from a “non-hydrothermal” coral (C-29), collected 10 km north of Tutum Bay, was analyzed for comparative purposes. Density banding is moderately well developed in these corals and subannual bands are common. For corals from Tutum Bay, δ13C ranges from −4.5 to −1.0‰ and δ18O from −6.0 to −3.8‰, which are relatively depleted values for shallow water Porites. The comparison sample, C-29, has δ13C values ranging from −1.8 to −0.5‰, and δ18O values of −5.4 to −4.6‰. Concentrations of As, Co, Cr, Ga, Ge, Mo, Nb, Ni, Pb, Rb, Se, W, Y and Zr were always below their respective proton probe detection limits. Ba, Br, Cu, Fe, Mn, and Zn were detected in some samples. Sr was detected in all samples and concentrations ranged from 6970 to 8240 ppm. Strontium isotope ratios of selected samples (C-5, C-8 and C-29) are very close to seawater, but Tutum Bay corals (C-5 and C-8) have lower 87Sr/86Sr values than the “non-hydrothermal” sample (C-29). The observed isotope patterns indicate that the hydrothermal input into Tutum Bay influences the physico-chemical conditions in the surrounding coral reef. Tutum Bay Porites lobata show distinctly different δ13C and 87Sr/86Sr records when compared to the “non-hydrothermal” sample and other corals from Papua New Guinea and elsewhere. Direct and indirect synergistic effects, including temperature, isotopic and chemical composition of vent fluids and the influence of pCO2 on the expression of photosynthetic and kinetic stable isotope fractionation factors, are the most likely explanation for the “hydrothermal” signal seen in these corals. The δ18O values are significantly correlated with the estimated amounts of hydrothermal exposure.
|
2022-09-09T03:40:26.415Z
|
85,667,625 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1570-7458.1995.tb01874.x",
"MAG": "2153987262",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Mamestra configurata (Walker) (Lep., Noctuidae) larvae were fed excised Brassica juncea (commercial brown mustard) or B. rapa cv. Tobin (Canola) foliage of three plant growth stages ‐ rosette (stage 2), stem elongation (stage 3) and flowering (stage 4). Relative consumption rates (RCRi) were not significantly different between the plant species. Within the B. juncea treatments, there were no significant growth stage differences in RCRi. However, within B. rapa, RCRi increased with advancing plant growth stage. Larvae fed B. juncea foliage had significantly reduced relative growth rates (RGRi) compared to larvae fed B. rapa foliage. Within the B. juncea treatments, RGRi decreased with advancing plant growth stage. There were no significant growth stage differences in RGRi in the B. rapa treatments. RGRi was inversely proportional to the levels of isothiocyanate‐releasing glucosinolates in the B. juncea treatments. RCRi was inversely proportional to the levels of indolyl glucosinolates in the B. rapa treatments. Levels of total phenols and catechols in B. juncea did not show any trend which could be related to growth stage effects in the insect nutritional indices. In B. rapa, levels of phenols and catechols in stage 3 and 4 foliage were lower than that of stage 2 foliage. Analyses of total nitrogen in field‐grown plants showed reductions in percent nitrogen from rosette to flowering stage foliage. The response of M. configurata to different growth stages of its host plants are discussed in relation to changing levels of allelochemicals and nitrogen.
|
2022-09-12T05:51:38.506Z
|
253,626,963 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/nar/gkac988",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
With more and more data being collected, modern network representations exploit the complementary nature of different data sources as well as similarities across patients. We here introduce the Variation of information fused Layers of Networks algorithm (ViLoN), a novel network-based approach for the integration of multiple molecular profiles. As a key innovation, it directly incorporates prior functional knowledge (KEGG, GO). In the constructed network of patients, patients are represented by networks of pathways, comprising genes that are linked by common functions and joint regulation in the disease. Patient stratification remains a key challenge both in the clinic and for research on disease mechanisms and treatments. We thus validated ViLoN for patient stratification on multiple data type combinations (gene expression, methylation, copy number), showing substantial improvements and consistently competitive performance for all. Notably, the incorporation of prior functional knowledge was critical for good results in the smaller cohorts (rectum adenocarcinoma: 90, esophageal carcinoma: 180), where alternative methods failed.
|
2022-12-02T10:10:49.661Z
|
13,307,075 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/ije/dyq007",
"MAG": "2151921968",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://academic.oup.com/ije/article-pdf/39/4/1006/2367472/dyq007.pdf"
}
|
BACKGROUND
The role of trigger factors in acute cardiovascular events has been much studied in the past few years. A recent study analysed changes in the rates of cardiac emergencies in Bavaria (Germany) during the last Football World Cup. The authors reported a 2.7-fold increase in the incidence of cardiac emergencies in the 12 h before and after football matches involving the German team, which sparked the debate on the necessity of the introduction of ad hoc cardiovascular preventive measures.
METHODS
We studied 25,159 hospital admissions for acute myocardial infarction (AMI) among the Italian population during three international football competitions: the World Cup 2002, the European Championship 2004 and the World Cup 2006. Poisson regression was used to estimate the relative risk of hospital admission for AMI on the days when football matches involving the Italian team were disputed, compared with the other days of the three competitions. Furthermore, we reviewed the available published studies regarding the association between football matches and the risk of cardiovascular events.
RESULTS
We did not find an increase in the rates of admission for AMI on the days of football matches involving Italy in either the single competitions or the three competitions combined (relative risk 1.01; 95% confidence interval 0.98-1.05). We identified 10 studies published on this topic. With the exception of the recently published German study and two small Swiss studies, all relative risk estimates were between 0.7 and 1.3.
CONCLUSIONS
The cardiovascular effects of watching football matches are likely to be, if anything, very small.
|
2022-12-17T07:28:52.919Z
|
6,735,294 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/BIOINFORMATICS/4.1.19",
"MAG": "2149202424",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Given two sequences, a pattern of length m, a text of length n and a positive integer k, we give two algorithms. The first finds all occurrences of the pattern in the text as long as these do not differ from each other by more than k differences. It runs in O(nk) time. The second algorithm finds all subsequence alignments between the pattern and the test with at most k differences. This algorithm runs in O(nmk) time, is very simple and easy to program.
|
2022-12-18T11:43:55.480Z
|
35,718,907 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/jog.13143",
"MAG": "2531730014",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The aim of this study was to compare the outcome of two single‐incision mini‐slings (the Contasure‐Needleless [C‐NDL] and the endopelvic free anchorage) with the standard midurethral transobturator tension‐free vaginal tape (TVT‐O) procedure.
|
2022-12-17T18:18:59.982Z
|
54,964,956 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.18260/1-2--29016",
"MAG": "2742211137",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://peer.asee.org/29016.pdf"
}
|
Jeffrey T La Belle is currently an Assistant Professor in the School of Biological Health and Systems Engineering and the Biodesign Institute at Arizona State University. He holds adjunct status in the School of Energy and Matter Transport (Mechanical Engineering) as well as the College of Medicine at Mayo Clinic. He has a Ph.D. and Masters in Biomedical Engineering from ASU and a MS and BS in Electrical Engineering from Western New England University in Springfield Massachusetts. In the La Belle Group, we are currently developing electrochemical sensors for noninvasive glucose sensing, the novelty of our design is to obtain tear fluid for tear to blood glucose correlation in a noninvasive means to increase patient compliance. The next leap in technology for diabetes care is a multiplexed sensor that will add more depth of information for a self-monitoring blood glucose devices, here five accepted markers for DM care and management, including glucose, HbA1c, among others are simultaneously monitored on a single strip sensor. This technology we are developing could also allow for continuous and single use stress/trauma sensing technologies. Other applications of the sensing technologies include small molecule, DNA, protein, and whole cell detection to address changing climate in point-of-care technologies and medicine. On the activation side of our research, we are fabricating nitinol staggered muscle arrays that mimic skeletal muscle and we have recently demonstrated over 30% compression in our SMA’s similar to muscle bundles. Our approach to design is simple, following FDA guidelines and suggestions from the start, look at what the user needs and/or wants and apply a unique solution. We have a well-diversified group to tackle the challenges in health care today, staff and students come from biomedical engineering, electrical engineering, mechanical engineering, chemical engineering, computer science engineering, as well as biology and chemistry programs at ASU. BME at ASU teaches a 8 semester wide medical device design tract that initiates the students in design, regulations, standards, IP and other aspects from day 1. Dr. La Belle has develop and courses and taught at the freshman, junior, senior and graduate level on these topics.
|
2022-12-30T00:16:19.902Z
|
2,921,030 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1108/09526860910964843",
"MAG": "2092179698",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
PURPOSE
The purpose of this article is to present a comprehensive structural equation based service quality and patient satisfaction model taking into account the patient's condition before and after discharge. The authors aim to test for causality in a sample of patients from United Arab Emirates public hospitals.
DESIGN/METHODOLOGY/APPROACH
Data were collected using questionnaires completed by adults discharged (n = 244) from UAE public hospitals. The proposed model consists of five main constructs. Three represent service quality: quality of care (four variables); process and administration (four variables) and information (four variables). There is also one construct that represents patient's status (two variables--health status before admission and after discharge). Finally, there is one construct that represents patient's satisfaction with care (two variables--general and relative satisfaction). Structural equation modeling and LISREL using maximum likelihood estimation was used to test hypothesized model(s)/parameters(s) derived deductively from the literature.
FINDINGS
The structural equation modeling representation provides a comprehensive picture that allows healthcare constructs and patient satisfaction causality to be tested. The goodness-of-fit statistics supported the healthcare quality-patient status-satisfaction model.
ORIGINALITY/VALUE
The model has been found to capture attributes that characterize healthcare quality in a developing country and could represent other modern healthcare systems. Also, it can be used to evaluate other healthcare practices from patients' viewpoints. The study highlights the importance of healthcare quality as patient satisfaction predictors by capturing other effects such as patient status.
|
2023-01-02T04:30:32.840Z
|
134,136,430 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/09720502.2017.1382147",
"MAG": "2769020038",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract An analysis was conducted for the land use and land cover dynamic characteristics in all county regions of Zhalong Wetland in 1979-2006 using the remote sensing and GIS technologies based on the Landsat TM images data of four periods of 1979-2006, and the results showed that: with the continuous development of land, the land use degree in all county regions of Zhalong Wetland increased gradually in the late 1970s to the early period of this century, except Tailai County, all the highest land use degrees appeared in the early period of this century. Overall, the area of arable land in all counties of Zhalong Wetland increased while the area of bare land decreased, the two opposite variation trends showed that the occupation of bare land by arable land had become a fact to be reckoned with.
|
2022-01-27T06:30:51.362Z
|
233,781,786 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1757-899X/1126/1/012053",
"MAG": "3145889337",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
It is evident that the future energy demand can be compensated by using solar energy. The technological improvements are needed to trap the sunlight and have to be utilized in an efficient way. It mainly depends on the type of material which is to be used for this purpose. Solar energy can be effectively captured and utilized to heat the heat transfer fluids. Therefore the usage of solar energy is a right choice as it has the ample availability in countries like India.Solar cavity collector [SCC] is a kind of improvised, modified and redesigned construction of a solar Flat Plate Collector (FPC). In short, SCC is an upgraded and advanced version of FPC. A Copper pipe has been positioned concentrically fitted to a radius (outer) of 16 mm and placed into a metal box like structure having a size of 50 mm. In a similar way, five numbers of such cavities are formed. It has a provision for inlet and outlet water pipes. It has been designed, fabricated and experimented for its optimized level of performance. This paper explains about the usage of materials and solar selective surface coatings that are applicable to Solar Cavity Collector (SCC). The following experimental modifications are carried out in the SCC which are 1.Reciever materials of the SCC have been changed as aluminum and copper. 2. Cavity materials as Galvanized Iron (G.I) material and Mild Steel (M.S) material, both are experimented. 3. Solar selective coatings (SSC) of Black nickel have been used in SCC for the heat transfer improvement.
|
2022-02-07T21:46:38.962Z
|
155,798,354 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.13109/GEGE.2013.39.3.338",
"MAG": "2318856567",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract The inter-war years in Britain and Germany were a dynamic period in the development of goods transport; however, they were also years marked by debate around the so-called “rail-road problem”, the perceived unhealthy competition between railways and trucks, and its remedies. The paper interprets the attempts to manage this arena via regulation as social engineering and locates these practices in a transnational discourse within which a “right” order of society was to be realized by a heterogeneous group of transport experts. The analysis also reveals the diversity of these practices of social engineering: the aim of establishing a coordinated transport system was served by combining regulatory interventions with attempts to make room for the self-organization of the transport sector.
|
2022-02-09T01:08:25.564Z
|
239,845,720 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1353/pla.2021.0034",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
[...]we met more frequently, with fuller attendance, allowing us to advance the work described in this editorial, thanks especially to the volunteerism of board members who offered to take on additional assignments.3 “We Can Do Better” One year ago, we published the first editorial ever coauthored by portal’s full Editorial Board. According to the Society for Learning Analytics Research (SoLAR), learning analytics is defined as “the measurement, collection, analysis and reporting of data about learners and their contexts, for purposes of understanding and optimizing learning and the environments in which it occurs.” A working group of board members, chaired by Kyle M. L. Jones and including Consuella Askew, Donna Ferullo, and Mark Stover, drafted a set of recommendations. Because of their work, portal has taken the position that while library learning analytics research holds potential, it also is replete with ethical concerns, not least of which is the possibility of reidentifying previously de-identified data. [...]authors are expected to address relevant ethical issues if their research is a learning analytics study or involves any other work gathering or reporting data on human subjects.
|
2022-07-10T04:36:43.040Z
|
95,386,283 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5585/EXACTA.V4I1.661",
"MAG": "1997305983",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We observed UV luminescence from 4f 2 5d and 4f 3 configuration in Nd doped YLF and LLF crystals induced by multiphotonic excitation of the three photons (532nm).The LLF lattice is more compact than the YLF crystal and favours an absorption and emission shift of the main peaks due to crystal field strength . The red (and blue ) shfitings of the emission bands towards to lower (and higher) energy are different for the transitions from 4f 3 and 4f 2 5d levels. The 4f 3 transitions have smaller shift (~5 times smaller than the shift of the 4f 2 5d) due to 5s 2 5p 6 closed-shell shielding effect. On the other hand the 4f 2 5d transitions are more susceptible to lattice change. The effect of the crystalline field was compared for both lattice. The resut shows that these emission bands from 4f 2 5d configuration always shift to lower energy when substituting the Y 3+ by Lu 3+ (i.e, the last one has the ionic radius 5% smaller than Y 3+ ).
|
2022-08-20T18:47:30.629Z
|
333,758 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4018/IRMJ.1989010104",
"MAG": "2085287516",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Human resource information systems HRIS have vastly improved structured human resource management decision making while failing to improve semi-or unstructured decision making. This paper describes a human resource decision support system HRDSS which integrates DSS capabilities with those of HRIS to overcome the limitations inherent in the design of HRIS.
|
2022-09-03T05:49:59.403Z
|
161,187,463 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5209/CHMO.25101",
"MAG": "1866116041",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
1992 es un extraordinario anojubilar en el que se conmemoran acontecimientos politicos, sociales y culturales que conmovieron a occidente. Entre esos hechos esta la aparicion de la primera gramatica de una lengua romance —precisamente el 18 de agosto, en Salamanca ‘—, la Gramatica de la lengua castellana de Elio Antonio de Nebrija 2 y del Diccionario latinoespanoL tambien del humanista sevillano, muchas veces considerado como el primer diccionario espanol. Digamos que es el primer repertorio lexico extenso y moderno que recoge nuestra lengua, y haremos justicia a la verdad, lo cual no quita ni un apice de importancia ni al autor ni a la obra, pues entre sus predecesores hay que tener en cuenta, al menos, al otro humanista y cronista real, Alfonso Fernandez de Palencia, a quien se debe, entre otras obras, el Universal vocabulario en latin y romance ~. Elio Antonio fue un autor enormemente prolijo, por lo que en las paginas siguientes me ocupare tan solo de su labor como lexicografo. Es en la dedicatoria del diccionario donde Nebrija escribio aquello de que «io fue el primero que abri tienda dela lengua latina: y ose poner pendon para nuevos preceptos: como dize aquel oraciano catio. Y que ia casi del todo punto desarraigue de toda espana los doctrinales, los pedros ellas. y otros nombres aun mas duros los gaiteros. los ebrardos. pastranas: y otros no se que apostizos y contrahechos grammaticos no merecedores de ser nombrados», donde expone las intenciones que perseguia con la gramatica y el diccionario, como debelador de la barbarie. Pero hay algo mas en
|
2022-09-15T12:13:32.973Z
|
24,228,648 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1371/annotation/9fbcbbe8-8155-4611-9de1-8708de029017",
"MAG": null,
"PubMedCentral": "3734335"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://journals.plos.org/plosone/article/file?type=printable&id=10.1371/journal.pone.0046474"
}
|
We spliced the promoters of the human telomerase and human survivin genes (PhTERT and PhSurv, respectively) widely used for gene therapy and known to have the broadest cancer type spectrum of activity. Two head-to-tail constructs were obtained: the PhTERT-PhSurv and PhSurv-PhTERT tandems. The splicing caused quantitative and qualitative changes in the promoter features. In both constructs, only the promoter proximal to the transcribed gene retained its ability to initiate transcription, whereas the distal promoter was silent, the phenomenon never reported before. However, the distal promoter modulated the activity of the proximal one by increasing its strength and causing an appearance of additional transcription start sites. We suggested that this suppression might be due to the presence of Sp1 transcription factor binding sites in both promoters and Sp1-bridges between these sites. Such Sp1-bridges might convert the tandem promoter linear DNA into a stem-loop structure. If localized inside the formed loop, the distal promoter could lose its ability to initiate transcription. To test this hypothesis, we constructed two modified double promoters, where the proximal PhSurv promoter was replaced either by a shortened variant of the survivin promoter (PhSurv269) or by the mouse survivin promoter. Both PhSurv substitutes were considerably shorter than PhSurv and had different numbers and/or positions of Sp1 sites. In modified tandems, transcription was initiated from both promoters. We also prepared two mutant forms of the PhSurv-PhTERT tandem with two or four Sp1 sites removed from the distal ''long'' PhSurv promoter. In the first case, the distal PhSurv promoter remained silent, whereas the removal of four Sp1 binding sites restored its activity. In the majority of studied cancer cell lines the efficiency of transcription from the hTERT-(shortened hSurv269) promoter tandem was markedly higher than from each constituent promoter. In normal lung fibroblast cells, the tandem promoter activity was considerably lower. Copyright: ß 2012 Alekseenko et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
|
2022-09-30T01:26:29.724Z
|
2,162,402 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/002215549704500105",
"MAG": "2166513786",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
Carbonic anhydrase (CA) isoenzymes have been widely studied in the gastrointestinal tract, where they mediate membrane transport events and pH regulation. However, the esophagus has generally received scant attention. In an immunohistochemical study confirmed by Western blotting, we have detected four CA isoenzymes (CAI, II, III, and IV) in the epithelium of human esophagus. Isoenzymes I, III, and sometimes IV (<10%) were present in the cytoplasm of basal cells and II and IV in the cytoplasm and cell surface membranes, respectively, of suprabasal cells (prickle cells). The localization of CAIV to the plasma membranes was confirmed by electron microscopic immunocytochemistry. CA was effectively divided at the basal-suprabasal interface between low-activity CAI and III (basal) and high-activity CAII and IV (suprabasal). Carbonic anhydrase in esophageal epithelial cells may have several functions: elimination of CO2 and metabolites, participation in membrane transport events during active cell growth, and pH regulation as a protective mechanism against acidic gastric reflux.
|
2022-12-03T20:28:39.943Z
|
53,547,637 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2514/6.2016-4612",
"MAG": "2498094359",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://hal.archives-ouvertes.fr/hal-01392448/file/thauvin_16020.pdf"
}
|
This article assesses the benefits of hybridization within the regional aircraft scale using a conventional twin-turbo propeller aircraft as reference. For a fair comparison, this reference aircraft was designed assuming a 2035 technology level. The propulsion system of the reference aircraft is analyzed along the mission and the phases of flight with low efficiencies are highlighted. Then the potential benefits of new power management through the use of secondary power generation systems but also through the variation of the size of prime movers are presented and discussed. In particular, the effect of the gas turbine size on its efficiency is studied. Finally, the article focuses on aerodynamic improvements enabled by new propeller or fan integrations and the associated concepts such as differential thrust, blown wing and boundary layer ingestion. For each topic, simplified analyses provide estimated potential of energy saving. These results can be used as indicators for selecting the most promising hybrid architecture concepts for a regional aircraft.
|
2022-12-02T11:20:53.156Z
|
199,549,887 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/molecules24162908",
"MAG": null,
"PubMedCentral": "6720718"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/1420-3049/24/16/2908/pdf?version=1565424753"
}
|
Aptamers are functional nucleic acids that bind to a range of targets (small molecules, proteins or cells) with a high affinity and specificity. Chemically-modified aptamers are of interest because the incorporation of novel nucleobase components can enhance aptamer binding to target proteins, while fluorescent base analogues permit the design of functional aptasensors that signal target binding. However, since optimally modified nucleoside designs have yet to be identified, information about how to fine tune aptamer stability and target binding affinity is required. The present work uses molecular dynamics (MD) simulations to investigate modifications to the prototypical thrombin-binding aptamer (TBA), which is a 15-mer DNA sequence that folds into a G-quadruplex structure connected by two TT loops and one TGT loop. Specifically, we modeled a previously synthesized thymine (T) analog, namely 5-furyl-2′-deoxyuridine (5FurU), into each of the six aptamer locations occupied by a thymine base in the TT or TGT loops of unbound and thrombin bound TBA. This modification and aptamer combination were chosen as a proof-of-principle because previous experimental studies have shown that TBA displays emissive sensitivity to target binding based on the local environment polarity at different 5FurU modification sites. Our simulations reveal that the chemically-modified base imparts noticeable structural changes to the aptamer without affecting the global conformation. Depending on the modification site, 5FurU performance is altered due to changes in the local environment, including the modification site structural dynamics, degree of solvent exposure, stacking with neighboring bases, and interactions with thrombin. Most importantly, these changes directly correlate with the experimentally-observed differences in the stability, binding affinity and emissive response of the modified aptamers. Therefore, the computational protocols implemented in the present work can be used in subsequent studies in a predictive way to aid the fine tuning of aptamer target recognition for use as biosensors (aptasensors) and/or therapeutics.
|
2022-12-02T10:50:50.909Z
|
46,586,669 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1046/j.1524-4741.2003.09304.x",
"MAG": "2099928658",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract: Axillary nodal status is the most significant prognosticator for predicting survival and guiding adjuvant therapy in breast cancer patients. Sentinel lymph node biopsy (SLNB) represents a minimally invasive procedure with low morbidity for staging axillary nodal status. In this article we review and report our experiences in patients with early breast cancer who underwent SLNB at the Revlon/UCLA Breast Center. Between September 1998 and May 2000, a total 83 SLNBs were performed in 81 patients with proven breast cancer and negative axillary examination who elected to have SLNB as the first step of nodal staging. Two patients had bilateral breast cancer. SLNB was localized by using both 99Tc sulfur colloid (83 cases) and isosulfan blue dye (75 cases). Data of these patients were prospectively collected and analyzed. The clinical and pathologic characteristics of women with positive and negative sentinel lymph nodes (SLNs) were compared to identify features predictive of SLN metastasis. Of the 83 cases, the SLN was successfully localized in 82 (98.8%). Sixty‐three percent of patients had SLNs found in level I only, 18.3% in both level I and II, and 4.9% in level II alone. The vast majority (84.3%) of these cases had T1 breast cancer with an average size of 1.55 cm for the entire series. Twenty‐three patients (28%) had positive SLNs, with an average of 1.5 positive SLNs per patient. Fifteen had metastases detected by hematoxylin and eosin staining and 8 had micrometastases detected by immunohistochemistry (IHC) using anticytokeratin antibodies. Ten of the former group agreed to and 2 of the latter group opted for full axillary lymph node dissection (ALND). An average of 17.5 lymph nodes were removed from each ALND procedure. Additional metastases or micrometastases were found in seven patients (in a total of 28 lymph nodes). Three patients with completely negative SLNs experienced additional axillary lymph node removal due to their election of free flap reconstruction. None had metastases detected in these lymph nodes. The absence of estrogen and progesterone receptors (ER/PR) by IHC (p = 0.036) and the presence of lymphatic/vascular invasion (LVI) (p = 0.002) predicted positive SLNs in patients with early breast cancer in a univariate analysis; in a multivariate analysis only LVI was predictive (p = 0.0125). Histologic type, nuclear grade, tumor differentiation, HER‐2/neu and p53 status, S‐phase fraction, and DNA ploidy did not predict SLN status. Immediate postoperative complications were uncommon and delayed complications completely absent. Because of the high detection rate, accurate staging, and minimal morbidity, SLNB should be offered as a choice to women with small breast cancers and clinically negative nodes. Because positive LVI and negative ER/PR status are highly predictive of pathologically positive SLNs in small breast cancers, women whose cancers meet these criteria should be advised preoperatively about their risk of having a positive SLN and may benefit from intraoperative assessment (frozen section and/or touch preparation) of their SLNs.
|
2022-12-16T04:06:48.132Z
|
26,795,205 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/FGCT.2013.6767192",
"MAG": "1974227108",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In the last decade, many analytical models have been proposed to compute the performance of IEEE 802.11 DCF under non-saturated conditions. In this paper, we propose a new analytical model which can be employed for computing the performance throughput for both saturated and non-saturated networks. We have considered the presence of first order memory buffer and traffic arrival which obeys Poisson distribution. In comparison to other models, our model can predict the behavior more accurately. The same has been verified by elaborate modeling and simulation results.
|
2022-12-17T07:23:12.254Z
|
41,740,552 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/00004770-200212000-00002",
"MAG": "1969829802",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The purpose of this study was to investigate possible changes in cutting efficiency of nickel-titanium K-files that had undergone physical vapor deposition coating. Titanium nitride coatings were deposited using different process parameters. A total of 84 nickel-titanium K-files (size 35) were randomly divided into 7 groups of 12 instruments each. Groups A to F (experimental): instruments were coated with titanium nitride using different process parameters regarding substrate temperature, applied voltage, coating thickness, and ion bombardment. Group K (control): samples were not coated with titanium nitride. The cutting efficiency of all instruments was determined in a rotary working motion by means of a computer-driven testing device. Special plastic samples with a cylindrical canal were used, and the maximum penetration depth of the instruments into the lumen was the criterion for cutting efficiency. Instruments of groups A, F, and C achieved significantly greater penetration depths than the uncoated instruments of the control group (p < 0.05). Cutting efficiency of physical vapor deposition-coated nickel-titanium files was increased by up to 26.2% in comparison with uncoated instruments.
|
2022-12-20T05:30:54.324Z
|
45,894,287 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/IMCCC.2014.21",
"MAG": "1975925468",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
With external disturbances, an robust synchronization control approach is present. Then the robust synchronization control system comprises a disturbances observer and an controller. The disturbances observer is used to estimating the disturbances. And the errors of vessels are introduced to the controller. Meanwhile, the stability of the disturbances observer and the controller are proved by the Lyapunov theory. Finally, simulations are carried out to show effectiveness of the proposed control strategy.
|
2022-01-27T10:26:02.196Z
|
153,596,741 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4324/9780203880180",
"MAG": "1567516403",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
1. Overview Part I: Inflation and Welfare 2. The Welfare Costs of Inflation in a Cash in Advance Model with Costly Credit 3. A Comparison of Partial and General Equilibrium Estimates of the Welfare Cost of Inflation 4. The Optimality of a Zero Inflation Rate: Australia 5. On the Optimality of Restricting Credit: Inflation-Avoidance and Productivity 6. Ramsey-Friedman Optimality within a Banking Time Economy Part II: Money Demand and Velocity 7. The Demand for Bank Reserves and Other Monetary Aggregates 8. Money Velocity with Costly Credit 9. Money Demand in General Equilibrium Endogenous Growth: Estimating the Role of a Variable Interest Elasticity 10. Money Demand in an EU Accession Country: A VECM Study of Croatia Part III: Inflation and Growth 11. Inflation and Balanced-Path Growth with Alternative Payment Mechanisms 12. Contrasting Models of the Effect of Inflation on Growth 13. A Revised Tobin Effect from Inflation: Relative Input Price and Capital Ratio Realignments, US and UK, 1959-1999 14. Inflation and Growth: Explaining the Negative Effect 15. Granger Causality of the Inflation-Growth Mirror in Accession Countries Part IV: Monetary Business Cycles 16. On Keynes's Theory of the Aggregate Price Level in the Treatise: Any Help for Modern Aggregate Analysis? 17. Credit Shocks in the Financial Deregulatory Era: Not the Usual Suspects 18. A Comparison of Exchange Economies within a Monetary Business Cycle 19. Money Velocity in an Endogenous Growth Business Cycle with Credit Shocks 20. Epilogue: The Perspective Going Forward
|
2022-02-09T02:18:10.747Z
|
248,033,872 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/JU.0000000000002591.16",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
study period with cohort II reporting a baseline mean (median) score of 19.8 (19) and an end of study value of 16.8 (17.5). Serum lidocaine concentrations were measured at 1 hour, 1 day and 7 days. Serum concentrations were similar across all cohorts at day 1 indicating only local release of the medication. There were no serious adverse events (SAE's) reported in the study. All subjects reported at least one treatment-emergent adverse event (TEAE). Most TEAE's were mild or moderate and related to bruising or swelling at the injection site. CONCLUSIONS: ST-01 was safely injected in 12 subjects suffering from CSCP with a promising efficacy signal.
|
2022-05-13T00:46:15.758Z
|
28,616,073 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/HYP.7413",
"MAG": "2060087643",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Hydrological modelling depends highly on the accuracy and uncertainty of model input parameters such as soil properties. Since most of these data are field surveyed, geostatistical techniques such as kriging, classification and regression trees or more sophisticated soil‐landscape models need to be applied to interpolate point information to the area. Most of the existing interpolation techniques require a random or regular distribution of points within the study area but are not adequate to satisfactorily interpolate soil catena or transect data. The soil landscape model presented in this study is predicting soil information from transect or catena point data using a statistical mean (arithmetic, geometric and harmonic mean) to calculate the soil information based on class means of merged spatial explanatory variables. A data set of 226 soil depth measurements covering a range of 0–6·5 m was used to test the model. The point data were sampled along four transects in the Stubbetorp catchment, SE‐Sweden. We overlaid a geomorphology map (8 classes) with digital elevation model‐derived topographic index maps (2–9 classes) to estimate the range of error the model produces with changing sample size and input maps. The accuracy of the soil depth predictions was estimated with the root mean square error (RMSE) based on a testing and training data set. RMSE ranged generally between 0·73 and 0·83 m ± 0·013 m depending on the amount of classes the merged layers had, but were smallest for a map combination with a low number of classes predicted with the harmonic mean (RMSE = 0·46 m). The results show that the prediction accuracy of this method depends on the number of point values in the sample, the value range of the measured attribute and the initial correlations between point values and explanatory variables, but suggests that the model approach is in general scale invariant. Copyright © 2009 John Wiley & Sons, Ltd.
|
2022-10-06T16:21:03.962Z
|
211,833,482 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/cells9030553",
"MAG": "3009715793",
"PubMedCentral": "7140419"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2073-4409/9/3/553/pdf?version=1583148017"
}
|
Protein kinase C (PKC) isozymes are members of the Serine/Threonine kinase family regulating cellular events following activation of membrane bound phospholipids. The breakdown of the downstream signaling pathways of PKC relates to several disease pathogeneses particularly neurodegeneration. PKC isozymes play a critical role in cell death and survival mechanisms, as well as autophagy. Numerous studies have reported that neurodegenerative disease formation is caused by failure of the autophagy mechanism. This review outlines PKC signaling in autophagy and neurodegenerative disease development and introduces some polyphenols as effectors of PKC isozymes for disease therapy.
|
2022-12-02T11:09:10.485Z
|
20,534,418 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1469-8749.1985.tb04558.x",
"MAG": "2169002788",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Kalen and Bleck also use the Perkins’ line to indicate the percentage of subluxation, but for most CP children this percentage is not stationary with time. For this reason I have designated it ‘migration percentage’. For the same reason, it is not sufficient to compare the preoperative and postoperative percentages: in the light of our present knowledge we must compare the inward or outward migration before the intervention with the migration afterwards. I have designated this value the ‘migration index’. I presume that Kalen and Bleck also individualize the I suggest that it is the same false extension of the adductor tenomyotomy according to the outward migration of the hip, the degree of muscle imbalance, age, etc. The reason f o r their better results after combined iliopsoas and adductor tenotomy than after adductor operations alone might be that more adductors were cut in the former cases than in the latter.
|
2022-12-03T19:55:04.148Z
|
20,164,673 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1524-4725.2006.32076.X",
"MAG": "2038293039",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
BACKGROUND Microdermabrasion has become a popular method for superficial resurfacing of the epidermis. Despite the popularity of this technique, few studies have examined changes in the levels of lipids (especially ceramide) in the stratum corneum following microdermabrasion. OBJECTIVE To assess and analyze changes in the ceramide level in the stratum corneum during the course of serial aluminum oxide microdermabrasion. METHODS Eleven healthy volunteers were enrolled in this study. Each participant underwent microdermabrasion once a week for 5 weeks. Following each procedure, the ceramide level in the resulting epidermal scales was measured. RESULTS A statistically significant increase in the ceramide level in the stratum corneum was observed following the first and second microdermabrasion sessions. After the third and fourth sessions, the ceramide level returned to baseline. CONCLUSION The results suggest that microdermabrasion alters the epidermal ceramide level. These findings provide the first evidence of alterations in the lipid barrier following microdermabrasion.
|
2022-12-17T11:49:39.263Z
|
155,703,892 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4324/9780203797839",
"MAG": "2618070762",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
Human rights based budget analysis projects have emerged at a time when the United Nations has asserted the indivisibility of all human rights and attention is increasingly focused on the role of non-judicial bodies in promoting and protecting human rights. This book seeks to develop the human rights framework for such budget analyses, by exploring the international law obligations of the International Covenant on Economic, Social and Cultural Rights (ICESCR) in relation to budgetary processes. The book outlines international experiences and comparative practice in relation to economic and social rights budget analysis and budgeting.The book sets out an ICESCR-based methodology for analysing budget and resource allocations and focuses on the legal obligation imposed on state parties by article 2(1) of ICESCR to progressively realise economic and social rights to 'the maximum of available resources'. Taking Northern Ireland as a key case study, the book demonstrates and promotes the use of a ‘rights-based’ approach in budgetary decision-making.The book will be relevant to a global audience currently considering how to engage in the budget process from a human rights perspective. It will be of interest to students and researchers of international human rights law and public law, as well as economic and social rights advocacy and lobbying groups.
|
2022-12-19T21:40:59.452Z
|
110,925,022 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1117/12.534753",
"MAG": "2094004955",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper presents a novel wafer baking system that uses hot air streams as heating media and achieves good temperature uniformity across the entire wafer surfaces during the baking process. Wind tunnel experiments have been carried out to verify the concept of using hot air streams for wafer baking. A simple prototyping wafer baking system has been designed and fabricated, and experiments of the baking process have been conducted. Good temperature uniformity across the wafer surface has been achieved. The experimental results match well with the computer fluid dynamics (CFD) simulation results. It is observed that the velocity of the airflow has significant influence on the temperature transient responses. Further optimization of the parameters of the baking system and analytical modelling studies are currently under way.
|
2022-02-10T04:38:34.310Z
|
14,593,206 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICTTA.2006.1684739",
"MAG": "1581995215",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Ray path parameters of line of sight radio links have been extracted from data such as variation of received field with height, frequency or time. Holographic techniques with the Fourier transform were also used. In this contribution, the effect of noise in the recorded data is investigated. The wavelet technique is employed for denoising the recorded data before processing. Such processing of data will reduce the limit on the signal to noise ratio S/N needed for the recorded data. Computer simulations showed that noisy data with S/N as low as 0 dB can be preprocessed by the wavelet technique to give satisfactory estimation of ray path parameters
|
2022-02-13T02:36:27.968Z
|
51,664,804 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/jaiee.1927.6535023",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
On the evening of Wednesday, January 19, 1927, the New York Section of the A. I. E. E. held a joint meeting with the Metropolitian Section of the A. S. M. E. in the Public Service Auditorium, Newark, N. J. The subject “Modern Central Station Design” proved very attractive as evidenced by an attendance of over 800. Four speakers covered both the mechanical and electrical sides of plant design as follows: E. B. Ricketts and R. H. Tapscott of the New York Edison Company on “The New East River Station” and R. J. S. Pigott and W. R. Smith of the Public Service Company on “The Kearney Station of the Public Service Company.” The talks, which in general covered the bulk generation of power, dealt particularly with the engineering features underlying the general design and arrangement of the plants. All talks were generously illustrated with lantern slides. Chairman E. B. Meyer of the N. Y. Section A. I. E. E. presided over the presentation of the papers and Chairman Frost of the A. S. M. E. over the discussion. The meeting was preceded by a very successful “Get-to-gether Dinner” at the Robert Treat Hotel, attended by 420 members and guests.
|
2022-02-11T22:51:54.507Z
|
82,607,923 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1271/BBB1961.42.941",
"MAG": "832265552",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The following ten new analogs of neohesperidin dihydrochalcone (DHC) (I) were synthesized: Hesperetin DHC-4′-β-l-glucopyranoside (II), hesperetin DHC-4′-[2-O-methyl-β-d glucopyranoside] (III), hesperetin DHC-4′-[3-O-methyl-β-d-glucopyranoside] (IV), hesperetin DHC-4′-[6-0-methyl-β-d-glucopyranoside] (V), hesperetin DHC-4′-β-d-glucopyranosiduronic acid (VI), hesperetin DHC-4′-β-maltotrioside (VII), hesperetin DHC-4′-[β-l-glucopyranosyl- (1→2)-β-d-glucopyranoside] (VIII), 3,2′,4′-trihydroxy-4-methoxydihydrochalcone-4′-[α-l- rhamnopyranosyl-(l→2)-β-d-galactopyranoside] (IX), 3,4′-dihydroxy-4-methoxydihydrochal- cone-4′-[α-l-rhamnopyranosyl-(l→2)-β-d-galactopyranoside] (X) and 4,2′,4′-trihydroxydihy- drochalcone-4′-[α-l-rhamn opyranosyl - (1→2)-β-d-galactopyranoside] (XI).Compounds II, III, IV, V, VII, VIII, IX, and X are 0.8, 2.0, 0.8, 4.0, 1.4, 0.02, 4.5 and 0.004 times as sweet as saccharin, respectively, while VI and XI are tasteless.
|
2022-08-24T19:27:01.355Z
|
122,058,665 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1002/PSSA.2210700203",
"MAG": "2140721656",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
An investigation is made of microstructural changes occurring during the superplastic flow, contribution of grain boundary sliding (GBS) and intragrain deformation (IGD) to overall deformation are estimated, a study is made of deformation mechanisms, and intimate relationship between deformation processes and pore formation is determined on the coarse-grained alloy Al-4 wt% Ge. It is demonstrated that superplastic flow of a coarse-grained material can take place in the case of grain boundary porosity which makes full accomodation unnecessary when GBS, which is the main deformation mechanism of superplastic flow, takes place. Intragrain dislocation slip (IDS) therewith plays mainly an accommodation part. The deformation model of superplastic flow is considered taking into account the role of grain boundary porosity in the superplastic flow.
[Russian Text Ignored].
|
2022-09-13T11:46:55.748Z
|
9,356,965 |
{
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"ArXiv": null,
"DOI": "10.1177/1049909110373507",
"MAG": "2091971956",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Opioids have become the gold standard for treatment of severe pain in advanced disease, but adverse effects can affect the quality of life. Opioid-induced bowel dysfunction can lead to refractory constipation. Methylnaltrexone bromide is a peripherally acting mu antagonist and is indicated for the treatment of opioid-induced constipation in patients with advanced illness, when response to standard laxative therapy has been inefficacious. This pharmacology update will review the etiology, pathophysiology, and treatment of opioid-induced constipation, focused on methylnaltrexone as a novel treatment for refractory cases.
|
2022-09-16T00:55:22.069Z
|
38,638,444 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1152/AJPLUNG.1996.270.5.L745",
"MAG": "2471967175",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This study investigated the effects of methacholine and terbutaline on the ciliary beat frequency (CBF) of upper airway epithelium. The CBF of cultured human adenoid explants was measured using microphotometry. Methacholine (10(-6) M) and terbutaline (10(-6)M) increased CBF a maximum of 23.0 +/- 1.8% (P < 0.001) and 16.5 +/- 2.3% (P < 0.001). Inhibition of endogenous nitric oxide (NO) production by nitro-L-arginine methyl ester (L-NAME) (10(-6) M) abolished the effects of methacholine in L-arginine-free medium (P < 0.008). This inhibition was reversed by addition of L-arginine. There was no inhibition of terbutaline-induced ciliostimulation by L-NAME (P < 0.5). KT-5823 (10(-6)M), a guanosine 3',5'-cyclic monophosphate (cGMP) kinase inhibitor, significantly inhibited the effects of methacholine (P < 0.0001), but not terbutaline (P > 0.15). H-89 (10(-6) M), a cAMP kinase inhibitor, significantly inhibited terbutaline-induced ciliostimulation (P < 0.0001), but not methacholine-induced ciliostimulation (P > 0.05). Diclofenac (10(-6) M), a cyclooxygenase inhibitor, significantly inhibited the effects of methacholine (P < 0.0007) but had no effect on terbutaline-induced ciliostimulation (P > 0.05). These findings suggest that the CBF of upper airway epithelium is modulated through at least two distinct pathways. The beta 2-adrenoceptor produces ciliary stimulation by a pathway involving increased intracellular cAMP levels, while the muscarinic receptor increases CBF by a mechanism involving production of prostaglandins, NO, and cGMP.
|
2022-09-30T15:41:17.646Z
|
238,478,460 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ACCESS.2021.3117363",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Aiming at the speed regulation problem of permanent magnet synchronous motor (PMSM) drives, a novel backstepping nonsingular terminal sliding mode control (BNTSMC) method with finite-time disturbance observer (FTDO) is proposed. In order to ensure excellent tracking and anti-disturbance performance, the backstepping nonsingular terminal sliding mode speed controller based on equivalent motor model and the recursive principle is designed for PMSM. The benefits of this approach are that the controller has asymptotic stability based on backstepping design and strong robustness for the matched disturbance based on sliding mode control. Then, to further improve the anti-disturbance performance, a finite-time disturbance observer is designed, and it is used to estimate the mismatched external disturbance in motor drive system. The stability of the system is also proved with Lyapunov criterion. Finally, the experimental results show that the proposed method has the advantages of fast convergence and strong robustness against parameter variations and external disturbance.
|
2022-12-04T19:59:37.131Z
|
32,612,501 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/NNE.0000000000000149",
"MAG": "2332186019",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Telehealth care is a fast-growing avenue of providing health care services at a distance. A descriptive study was conducted to identify trends of telehealth education in 43 schools of nursing. Findings reflected inadequate integration of telehealth in classroom content, simulation, and clinical experiences. Interviews with 4 nursing leaders of telehealth provided some recommendations on how to integrate telehealth education in nursing curricula.
|
2022-12-16T17:20:33.877Z
|
12,897,923 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S0022215100129809",
"MAG": "1996711000",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract A case of carcinoma ex pleomorphic adenoma arising in the soft palate is reported. The tumour presented had enlarged gradually over 10 years and finally occupied the oral cavity. The patient was admitted to our hospital due to disturbance of her speech and swallowing, and a sudden haemorrhage from the tumour. The initial pathological diagnosis by open biopsy was benign pleomorphic adenoma. After total resection, histological examination revealed that the tumour was composed partly of benign pleomorphic adenoma and partly of an adenocarcinomatous component. The carcinoma cells with prominent nucleoli were spheroid or polygonal in shape, and frequently formed ductal structures with areas of necrosis. Mitoses were also found. These findings showed that this tumour was a secondary carcinoma which had developed in a preexisting pleomorphic adenoma.
|
2022-12-16T12:40:29.637Z
|
16,411,392 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/1759-7714.12363",
"MAG": "2472047930",
"PubMedCentral": "5130210"
},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/1759-7714.12363"
}
|
Certain radiographic signs of a treatment response, such as cavitation, changes in density, or tumor change along a short axis, are not considered by Response Evaluation Criteria in Solid Tumors (RECIST). This study evaluates what additional prognostic information can be obtained by including these criteria in tumor assessment.
|
2022-12-20T13:11:21.967Z
|
205,135,714 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/febs.13161",
"MAG": "2088006571",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc4310827?pdf=render"
}
|
Uncoordinated 119 protein (UNC119) is a partner of transducin‐α subunit (Gαt) that is essential for transducin trafficking in rod photoreceptors. The interaction is known to involve binding of the acylated N terminus of Gαt to the hydrophobic pocket of UNC119. To gain insights into the mechanism of transducin trafficking, we isolated a highly pure protein complex between myristoylated chimeric Gαt (Gαt*) and UNC11950–240, and examined the solution structure by small angle X‐ray scattering and chemical crosslinking. The solution structure of the Gαt–UNC11950–240 complex was derived with rigid body/ab initio modeling against the small angle X‐ray scattering data by use of known atomic structures of Gαt and UNC119, and a distance constraint based on the protein crosslinking with p‐phenyldimaleimide. The model of the Gαt–UNC11950–240 complex indicates rotation and bending of the N‐terminal α‐helix of Gαt from its position in the structure of the heterotrimeric G‐protein transducin (Gt). This allows a considerably more compact complex conformation, which also suggests a novel interface involving the switch II/α3–β5 surface of Gαt. Supporting a novel interface, UNC119 was found to bind full‐length Gαt* more strongly than the Gαt N‐terminal peptide. Furthermore, UNC119 competed with the effector molecule phosphodiesterase‐6 γ‐subunit, which is known to bind to the same surface of Gαt. The solution structure of the Gαt–UNC119 complex suggests that the ability of UNC119 to dissociate Gt subunits and release Gαt from the membrane is attributable to disruption and sterical occlusion of the Gβ1γ1‐binding sites on Gαt.
|
2022-12-30T01:11:09.781Z
|
216,152,601 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/07907184.2011.593734",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Northern Ireland: A Comparative Analysis (F. Wright, 1987, Dublin: Gill and Macmillan) remains the most significant work of comparative historical analysis written on Ireland, yet its reputed difficulty has blunted its impact. This article reconstructs Frank Wright's research design and comparative method and situates the book in the research tradition of configurative macroanalysis pioneered by Barrington Moore. Wright's detailed, processual, analytic narratives comparing the breakdown of communal deterrence systems in Northern Ireland, the US South and Algeria have been relatively neglected in later literature. Those grounded comparisons focused on getting the concrete details of cases right while striving to build middle-range generalizations about ethnic stratification and political authority. His comparisons were morally serious searches for paths out of conflict, which analyzed the unfolding of temporal processes in ways that anticipated recent interest in path dependence; but Wright downplayed political institutions and overstated his categorical distinction between settlement colony and ethnic frontiers. Future comparative research on Northern Ireland should focus even more on variation across conflicts, including institutional change, but would benefit from re-engaging with A Comparative Analysis as a gateway to comparative historical analysis.
|
2022-01-27T02:33:34.403Z
|
60,666,491 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1117/12.498868",
"MAG": "1971339898",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper focuses on the mapping of low-cost and real-time super-resolution (SR) algorithms onto SOC (System-On-Chip) platforms in order to achieve high-quality image improvements. Low-cost constraints are accomplished by avoiding the need for specific SR hardware, by re-using a video encoder architecture. Only small modifications are needed for: the motion estimator, the motion compensator, image loop memory, etc. This encoder can be used either in compression mode or in SR mode. This video encoder together with the new SR features constitutes an IP block inside Philips Research, upon which several SOC platforms are being developed. Although this SR algorithm has been implemented on an encoder architecture developed by Philips Research it can be easily mapped upon other hybrid video encoder platforms. The results show important improvements in the image quality. Based on these results, some generalizations can be made about the impact of the sampling process on the quality of the super-resolution image.
|
2022-02-11T15:47:58.418Z
|
27,504,525 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1288/00005537-198511000-00007",
"MAG": "2050443310",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
Counseling of laryngectomy patients was studied by a questionnaire survey among 294 fellows of the American Society for Head and Neck Surgery and otolaryngology house officers (77% attendings and 23% residents). Seventy‐nine percent of respondents spent less than one hour counseling patients. Subjects emphasized during preoperative counseling included: extent of surgery, loss of speech, alternatives to surgery, immediate postoperative disfigurement, possible effects of surgery on life expectancy, and possibility of recurrence. At least 24% of physicians were unwilling to discuss the psychosocial effects laryngectomy.
|
2022-08-20T10:59:45.436Z
|
248,014,606 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/cells11071242",
"MAG": null,
"PubMedCentral": "8997467"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2073-4409/11/7/1242/pdf?version=1649241669"
}
|
Neuronal growth regulator 1 (NEGR1) is a brain-enriched membrane protein that is involved in neural cell communication and synapse formation. Accumulating evidence indicates that NEGR1 is a generic risk factor for various psychiatric diseases including autism and depression. Endoglycosidase digestion of single NEGR1 mutants revealed that the wild type NEGR1 has six putative N-glycosylation sites partly organized in a Golgi-dependent manner. To understand the role of each putative N-glycan residue, we generated a series of multi-site mutants (2MT–6MT) with additive mutations. Cell surface staining and biotinylation revealed that NEGR1 mutants 1MT to 4MT were localized on the cell surface at different levels, whereas 5MT and 6MT were retained in the endoplasmic reticulum to form highly stable multimer complexes. This indicated 5MT and 6MT are less likely to fold correctly. Furthermore, the removal of two N-terminal sites N75 and N155 was sufficient to completely abrogate membrane targeting. An in vivo binding assay using the soluble NEGR1 protein demonstrated that glycans N286, N294 and N307 on the C-terminal immunoglobulin-like domain play important roles in homophilic interactions. Taken together, these results suggest that the N-glycan moieties of NEGR1 are closely involved in the folding, trafficking, and homodimer formation of NEGR1 protein in a site-specific manner.
|
2022-10-07T00:19:25.516Z
|
253,170,312 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2139/ssrn.4248070",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper the evaluate the performance of the Mutual funds in Egypt by assessing their ability to attract investors savings and generate profitable returns to increase the volume of investment and achieve economic benefit, using annual dataset and employing a sharp and Treynor Indexes , our results show that the return rates on the listed funds were relatively low in Egypt, but some of the funds had higher returns than government treasury bills, which averaged 9.9213. The highest rate was 21.21% and 5.5% the lower rate of return. However, a number of funds achieved negative values as their rate return was lower than the rate of return on treasury bills, and the risk indicator in the Fund was higher as Faisal Bank mutual fund, which had 3.47% rate of return.
|
2022-10-28T16:15:54.686Z
|
237,678,122 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.5465/ambpp.2021.10673abstract",
"MAG": "3186819517",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Existing literature on institutional change focuses on change as a result of conflicts between challengers and proponents of the dominant institutional logic. Although it helps us understand how ch...
|
2022-01-27T02:52:40.205Z
|
12,231,117 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1212/WNL.27.5.471",
"MAG": "2115758348",
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},
"license": null,
"status": null,
"url": null
}
|
In 14 stroke patients showing angiographic recanalization of the occluded internal carotid artery or middle cerebral arterial axis, the postrecanalized angiograms demonstrated several findings that have been considered to be generally rare in cerebral infarction. These findings principally consisted of narrowing of arterial caliber in six cases (43 percent), mass effect in eight cases (57 percent), and capillary blush in five cases (36 percent).
|
2022-11-29T16:12:16.430Z
|
133,589,912 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1051/BIOCONF/20191303007",
"MAG": "2929150955",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Grapevines store non-structural carbohydrates (NSC) during late summer to sustain plant development at the onset of the following spring’s growth. Starch is the main stored carbohydrate, found in the wood-ray parenchyma of roots and canes. Although the relationship between hydraulic and plant photosynthetic performance is well-recognized, little research has been done on the long-term effects of drought in grapevines adopting different strategies to cope with water stress (i.e. isohydric and anisohydric). We performed our study by exposing two different grape cultivars (Syrah and Cabernet Sauvignon) to a short but severe drought stress, at two stages of the growing season (July and September). No marked differences in the physiological and hydraulic responses of the two varieties were found, probably due to our experimental conditions. However, anatomical and biochemical characterization of overwintering canes pointed out several interesting outcomes. We found a significant and parallel increase of starch and medullar ray number in both cultivars exposed to early water stress. We hypothesize that stressed vines limited their carbon allocation to growth, while shifting it to starch accumulation, with a most evident effect in the period of intense photosynthetic activity. We also speculate that a different aptitude to osmotic adjustment may underlay variation in starch increase and the specific involvement of bark NSC in the two cultivars.
|
2022-11-11T06:54:08.947Z
|
57,960,306 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/HAST.957",
"MAG": "2906565961",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The bioethical, professional, and policy discourse over brain death criteria has been portrayed by some scholars as illustrative of the minimal influence of religious perspectives in bioethics. Three questions then lie at the core of my inquiry: What interests of secular pluralistic societies and the medical profession are advanced in examining religious understandings of criteria for determining death? Can bioethical and professional engagement with religious interpretations of death present substantive insights for policy discussions on neurological criteria for death? And finally, how extensive should the scope of policy accommodations be for deeply held religiously based dissent from neurological criteria for death? I begin with a short synopsis of a recent case litigated in Ontario, Canada, Ouanounou v. Humber River Hospital, to illuminate this contested moral terrain.
|
2022-12-14T09:08:43.741Z
|
39,737,945 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.23919/EUCAP.2017.7928221",
"MAG": "2621194499",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this paper a ring resonator (RR) based band pass filter (BPF) is integrated in the power divider for simultaneous filtering and equal division functions. The proposed co-axial feeding mechanism for the RR ensures the BPF response. Exploiting band-pass characteristics and matching the filter to 70.7 Ω, the RR BPF is integrated in place of the conventional quarter wave transformer in the power divider. In order to ensure good output isolation and return loss (RL), a 50Ω extended transmission line and a resistor is used. Experimental validation was carried out by fabricating the proposed filtering divider. The simulated and measured S-parameter responses were found in good agreement at the fundamental design frequency of 3 GHz and fractional bandwidth of 15%.
|
2022-12-14T12:22:56.981Z
|
35,783,283 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4269/AJTMH.1999.60.193",
"MAG": "1823185412",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We assessed an Echinococcus granulosus hydatid fluid antigen-ELISA (EgHF-ELISA) as a serologic prescreening test for E. granulosus infections, supplemented by more specific confirmatory tests, including arc-5 immunoprecipitation and antigen B subunit 8-kD immunoblotting. The diagnostic sensitivity of the EgHF-ELISA was 91%. With regard to the test specificity of the EgHF-ELISA (overall = 82%), we observed relatively frequent cross-reactions in tumor patients (6%) and in patients with other parasitic diseases. Cestode-related cross-reactivity can be resolved by the complementary use of E. multilocularis-specific antigens or Taenia solium cysticercosis-specific immunoblotting. Immunoblotting based upon the detection of antibody reactivity to the 8-kD antigen of EgHF, or if appropriately detectable, to the 29-kD and 34-kD bands exhibited a 91% diagnostic sensitivity and an overall specificity of 97% or 94%, respectively. Thus, immunoblotting provided a 99% discrimination between seropositive pre-operative cystic hydatid disease cases and cross-reactive non-cestode parasitic infections or malignancies.
|
2022-12-21T03:29:26.620Z
|
201,731,109 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/molecules24173143",
"MAG": "2970352953",
"PubMedCentral": "6749358"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/1420-3049/24/17/3143/pdf"
}
|
Thione-containing nucleobases have attracted the attention of the scientific community for their application in oncology, virology, and transplantology. The detailed understanding of the reactivity of the purine derivative 8-thioguanosine (8-TG) with reactive oxygen species (ROS) and free radicals is crucial for its biological relevance. An extensive investigation on the fate of 8-TG under both reductive and oxidative conditions is here reported, and it was tested by employing steady-state photooxidation, laser flash photolysis, as well as γ-radiolysis in aqueous solutions. The characterization of the 8-TG T1 excited state by laser flash photolysis and the photooxidation experiments confirmed that singlet oxygen is a crucial intermediate in the formation of the unexpected reduced product guanosine, without the formation of the usual oxygenated sulfinic or sulfonic acids. Furthermore, a thorough screening of different radiolytic conditions upon γ-radiation afforded the reduced product. These results were rationalized by performing control experiments in the predominant presence of each reactive species formed by radiolysis of water, and the mechanistic pathway scenario was postulated on these bases.
|
2022-12-23T02:09:48.183Z
|
136,956,340 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S1431927612010392",
"MAG": "2039894096",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Extended abstract of a paper presented at Microscopy and Microanalysis 2012 in Phoenix, Arizona, USA, July 29 – August 2, 2012.
|
2022-12-30T00:46:59.316Z
|
158,082,604 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4995/LOGGIA.2018.7210",
"MAG": "2904892206",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Todos los oasis saharianos sufren un grave abandono debido a cuestiones económicas, sociales y políticas. Este abandono es también la causa principal de su degradación, lo que, a su vez, afecta tanto a los recursos económicos primarios como al palmeral y al entorno construido. Este último también lucha contra un sentimiento común de rechazo, como resultado de la creencia de que la vivienda tradicional es incómoda, sucia, no duradera e insalubre. Existe un proyecto de restauración dirigido por la Universidad de Cagliari en Figuig (Marruecos) encaminado a reflexionar sobre una nueva actitud en las intervenciones de conservación, que muestra que las acciones dirigidas a la reutilización de edificios, tradiciones constructivas y materiales tradicionales pueden llevar a una victoria para todas las partes, donde la memoria unida al hábitat, la identidad local y la microeconomía local adquieran un significado renovado y sustancial.
|
2022-12-16T15:27:05.237Z
|
37,644,782 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/acs.jafc.5b05437",
"MAG": "2333214477",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A vortex-assisted dispersive micro-solid phase extraction (VA-D-μ-SPE) based on cetyltrimethylammonium bromide (CTAB)-modified zeolite NaY was developed for preconcentration of carbamate pesticides in fruits, vegetables, and natural surface water prior to analysis by high performance liquid chromatography with photodiode array detection. The small amounts of solid sorbent were dispersed in a sample solution, and extraction occurred by adsorption in a short time, which was accelerated by vortex agitation. Finally, the sorbents were filtered from the solution, and the analytes were subsequently desorbed using an appropriate solvent. Parameters affecting the VA-D-μ-SPE performance including sorbent amount, sample volume, desorption solvent ,and vortex time were optimized. Under the optimum condition, linear dynamic ranges were achieved between 0.004-24.000 mg kg(-1) (R(2) > 0.9946). The limits of detection (LODs) ranged from 0.004-4.000 mg kg(-1). The applicability of the developed procedure was successfully evaluated by the determination of the carbamate residues in fruits (dragon fruit, rambutan, and watermelon), vegetables (cabbage, cauliflower, and cucumber), and natural surface water.
|
2022-12-30T18:01:52.491Z
|
124,634,528 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1556/060.2015.60.1.6",
"MAG": "2177215493",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "http://real.mtak.hu/37742/1/060.2015.60.1.6.pdf"
}
|
Countable words conveying a numeric code and are subject to accountability not quantified explicitly are amenable graduation and become potentially gradable. There are two types of graduation of words: implicitly and explicitly graded words emerging as a result of quantification. The meaning of each lexical unit is implemented in three main areas: graduation, modality, and modal-estimated.
|
2022-02-09T18:26:59.693Z
|
34,147,767 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/0091651X.1966.10120312",
"MAG": "2032207568",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract In a passage in Hamlet, the hero describes the changing imagery he sees in a cloud. The projection of definite shapes onto an amorphous stimulus strongly suggests a parallel to the Rorschach test. These responses are interpreted as though they occurred on a regular Rorschach protocol. Thus analyzed, they show the breakthrough of Oedipal impulses at a crucial turning point of the play.
|
2022-08-25T00:03:39.899Z
|
236,219,341 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/09658416.2021.1931261",
"MAG": "3170816485",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract For decades, there has been a debate over the effectiveness of written corrective feedback in second language writing pedagogy. Recently, research on the issue has gradually turned from whether to give corrective feedback in L2 writing to how it can be effective; however, pursuit for effective pedagogical practices are still underway. To address this issue, the study reports on how contextualized feedback through teacher scaffolding can be effectively provided in L2 argumentative writing instruction and thus promote integrated development of language and cognition. Multiple data were collected to track students’ learning processes, including classroom recordings, teacher feedback on students’ writing samples, and teacher-student individual writing conferences. Results revealed a significant improvement in students’ L2 written language accuracy and rhetorical genre skills and an evident progress in their language use appropriateness, though the rates of development can be subjected to individual language proficiencies. Results of the study can inform the development of an effective L2 writing pedagogy while shedding light on EFL learners’ argumentative writing developmental trajectories.
|
2022-10-21T15:28:29.096Z
|
86,020,503 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1365-2907.2005.00068.X",
"MAG": "2129887964",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We compiled a sample of 370 pine marten dens to test the hypothesis that a scarcity of sites leads to the use of suboptimal structures. 2. The sample was influenced by detection methods. Radio-tracking revealed cryptic dens but few natal dens; chance encounters revealed dens in buildings and other man-made structures. A total of 82.8% of natal dens were detected by chance encounters. 3. Most dens were associated with trees (44.3%), rocks (27.6%) and buildings (13.8%). The natal den subsample comprised buildings (44.3%), trees (22.8%), other man-made structures (17.1%) and rocks (14.3%). A total of 69.6% of dens were elevated and typically in structures offering limited shelter. Only 9.8% of all dens were in elevated tree cavities. 4. This diversity of dens reflects a scarcity of arboreal cavities. The alternative structures are suboptimal in terms of energetic costs and risks of predation, and this may limit breeding success in some populations.
|
2022-12-12T16:20:25.853Z
|