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255M
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15,466,200 |
{
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"DOI": "10.1109/MINES.2010.220",
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This paper issues the problem of fault diagnosis in high computing system. In order to solve this problem, i.e., correctly and efficiently detecting the anomaly nodes during the system operation, which is very similar to the principle of pattern recognition research work, thus we try to use some pattern recognition methods to analysis and solve fault diagnosis problem in this paper. And also we do some experiment and compare the results and finally get some useful conclusion to show that Kernel Eigenface and Kernel Fisherface methods achieve lower error rates than the ICA and PCA approaches in anomaly nodes detection.
|
2022-02-13T01:56:54.620Z
|
117,669,248 |
{
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"ArXiv": null,
"DOI": "10.1109/GLOCOM.1994.512811",
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|
We investigate a block detection strategy for hard limited MSK signals. In contrast to the published work of Leib and Pasupathy (see EEE-TC, vol.40, p.1430-1441, September 1992) on optimal incoherent block detection, only first order phase differentials are exploited. This reduces the implementation complexity of a block detector significantly, since no complex valued calculations are necessary. A near-maximum likelihood detection metric is derived by suitably approximating the joint probability density function of a block of phase differentials. It is shown that the proposed detection scheme approaches the performance of coherent detection with increasing block lengths. Compared to coherent antipodal signalling, a degradation in performance still remains which is determined by the predetection filter.
|
2022-09-14T03:42:39.319Z
|
158,986,467 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.3726/B11666",
"MAG": "2773382260",
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}
|
« Independant », « alternatif », « indie », « underground », « avant-garde », « de creation »... Depuis les annees 1970, la revendication d’independance a pris une importance grandissante dans les univers de production culturelle. Qu’elle se rapporte a des contenus, des methodes de travail ou des dispositifs de mediation, cette revendication propose une alternative a la domination des groupes et des productions mainstream. Son succes conduit cependant a s’interroger sur la coherence meme d’une notion progressivement transformee en label de qualite.
A travers douze contributions traitant de l’edition, du cinema, de la musique, des medias et de la vulgarisation scientifique, cet ouvrage montre en quoi l’independance releve d’une construction sociale tributaire de son environnement institutionnel et marchand. Des ondes aux ecrans, de l’Europe aux Etats-Unis, des managers aux artistes, il met en evidence le balancement entre artisanat de creation et recherche d’une structuration economique perenne.
En mettant a distance la denonciation ritualisee de l’hegemonie des majors et autres « grands groupes » et en s’appuyant sur des terrains ancres dans differents contextes nationaux, ce livre fait le pari d’une approche transversale pour mieux saisir la maniere dont l’independance irrigue et structure des filieres trop souvent envisagees de maniere cloisonnee. Il eclaire ainsi une categorie de reference des industries culturelles paradoxalement peu etudiee par les sciences sociales, et permet de saisir l’evolution des rapports de force dans des secteurs confrontes a une rationalisation economique et a des mutations technologiques de grande ampleur.
|
2022-10-28T00:19:54.889Z
|
138,785,043 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1557/PROC-460-201",
"MAG": "2314316133",
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}
|
A microstructure of the massively transformed {gamma}-TiAl ({gamma}{sub m}) phase in a Ti-48at.%Al alloy, which was heat treated in the high-temperature {alpha}-Ti (disordered hcp) single phase field (1,683 K), followed by ice water quenching, has been examined using high-resolution electron microscopy. The characteristic features of the microstructure originated from the {alpha}{yields}{gamma} massive transformation have been clarified in detail, which are as follows. (1) Extremely thin hcp plates (about 0.8--2nm in thickness), which are considered to be a retained {alpha} phase, are found to exist in the {gamma}{sub m} phase. (2) Twin boundaries are found to be not flat interfaces, that is, twin interfaces are not on the exact (111) mirror plane. This situation is attributed to the existence of a number of partial dislocations at the twin boundaries. (3) Antiphase relationship between the regions either side of the thin rotated domain wall is confirmed. The validity of this situation is explained by assuming that the thin rotated domain wall has been grown from a simple antiphase domain boundary. On the basis of these facts, mechanism of the {alpha}{yields}{gamma} massive transformation has been discussed.
|
2022-02-09T09:54:39.922Z
|
108,688,151 |
{
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"ArXiv": null,
"DOI": "10.1117/12.57715",
"MAG": "1964957489",
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}
|
Optical fiber sensors based on the amplitude modulation technique are discussed. According to their basic working principle, these sensors are classified into three classes: spectrometric, transducer, and all-fiber sensors. Examples of fiber-optic sensors developed for biomedical and environmental applications are given. Typical parameters of biomedical interest, which are conveniently monitored by fiber-sensors, are: temperature, pressure, blood flow, pH, pO2, pCO2, glucose, and immunological parameters. Other parameters of interest for environmental monitoring are CH4, other hydrocarbons polluting air and water, and trichloroethylene and chloroform.© (1992) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.
|
2022-02-10T06:54:46.241Z
|
72,013,594 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1001/ARCHOTOL.1993.01880230016003",
"MAG": "2029862172",
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|
Editorial Introduction The following article recounts a lifetime experience with an inheritable disorder not uncommonly seen by otolaryngologists—progressive sensorineural hearing loss. The author, Donna L. Sorkin, relates her insights into the disorder's effect on generations of her family, and its impact on her as a daughter, wife, mother, and professional consultant. She has refused to be limited by the impairment and now provides national leadership as the new Executive Director of Self Help for Hard of Hearing People Inc, an organization dedicated to enhancing autonomy among its hearing-impaired members. The author has faced a challenge she had no choice but to accept and found some workable solutions. It is our hope that biomedical advances will afford more and better solutions for Ms Sorkin, and others who are joined in similar challenges.
|
2022-02-11T10:20:42.107Z
|
5,277,651 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1111/joa.12078",
"MAG": "2104134334",
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"license": null,
"status": "GREEN",
"url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3972047"
}
|
Mineralisation of the tendon tissue has been described in various models of injury, ageing and disease. Often resulting in painful and debilitating conditions, the processes underlying this mechanism are poorly understood. To elucidate the progression from healthy tendon to mineralised tendon, an appropriate model is required. In this study, we describe the spontaneous and non‐pathological ossification and calcification of tendons of the hindlimb of the domestic chicken (Gallus gallus domesticus). The appearance of the ossified avian tendon has been described previously, although there have been no studies investigating the developmental processes and underlying mechanisms leading to the ossified avian tendon. The tissue and cells from three tendons – the ossifying extensor and flexor digitorum longus tendons and the non‐ossifying Achilles tendon – were analysed for markers of ageing and mineralisation using histology, immunohistochemistry, cytochemistry and molecular analysis. Histologically, the adult tissue showed a loss of healthy tendon crimp morphology as well as markers of calcium deposits and mineralisation. The tissue showed a lowered expression of collagens inherent to the tendon extracellular matrix and presented proteins expressed by bone. The cells from the ossified tendons showed a chondrogenic and osteogenic phenotype as well as tenogenic phenotype and expressed the same markers of ossification and calcification as the tissue. A molecular analysis of the gene expression of the cells confirmed these results. Tendon ossification within the ossified avian tendon seems to be the result of an endochondral process driven by its cells, although the roles of the different cell populations have yet to be elucidated. Understanding the role of the tenocyte within this tissue and the process behind tendon ossification may help us prevent or treat ossification that occurs in injured, ageing or diseased tendon.
|
2022-09-06T21:53:54.653Z
|
253,786,715 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.56726/irjmets31489",
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},
"license": null,
"status": "BRONZE",
"url": "https://doi.org/10.56726/irjmets31489"
}
|
Cloud computing is referred to as simply “the cloud,” and is the delivery of virtual resources on-demand, everything from applications to data centers is done over the Internet on a pay-for-use basis. All the resources virtually pooled in the Cloud are offered to the customers as a service on demand basis. Cloud computing is Internet based development and use of Information/computer technology whereby dynamically scalable and often computing resources are provided as a service through the Internet. Users need not have knowledge of expertise in, or control over the technology infrastructure in the cloud that supports them. This paper presents the various services offered by the Cloud Computing. The services of the cloud computing PaaS, SaaS and IaaS are important basic services, along which some other services of the cloud computing are also presented.
|
2022-11-25T01:10:44.268Z
|
28,042,672 |
{
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"ArXiv": null,
"DOI": "10.1227/NEU.0000000000000214",
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|
BACKGROUND: During surgery, various images as well as other relevant visual information are usually shown upon request with the help of operating staff. However, the lack of direct control over the display may represent a source of stress for surgeons, particularly when fast decision making is needed. OBJECTIVE: To present the development and initial clinical testing of an innovative device that enables surgeons to have direct intangible control of the intraoperative image-displaying monitor with standardized free-hand movements. METHODS: The originally developed intangible interface named “OPECT” is based on the commercially available gaming controller KINECT (Microsoft) and dedicated action-recognizing algorithm. The device does not require any sensors or markers fixed on the hands. Testing was done during 30 neurosurgical operations. After each procedure, surgeons completed the 5-item questionnaire for evaluation of the system performance, scaling several parameters from 1 (bad) to 5 (excellent). RESULTS: During surgical procedures, OPECT demonstrated high effectiveness and simplicity of use, excellent quality of visualized graphics, and precise recognition of the individual user profile. In all cases, the surgeons were well satisfied with performance of the device. The mean score value of answers to the questionnaire was 4.7 ± 0.2. CONCLUSION: OPECT enables the surgeon to easily have intangible control of the intraoperative image monitor by using standardized free-hand movements. The system has promising potential to be applied for various kinds of distant manipulations with the displaying visual information during human activities.
|
2022-11-17T18:19:28.841Z
|
5,255,047 |
{
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"ArXiv": null,
"DOI": "10.1039/c3cc44574g",
"MAG": "2076093145",
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},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc4012615?pdf=render"
}
|
A new phenyl-acetylene receptor containing a carbonaceous hydrogen bond donor activates anion binding in conjunction with two stabilizing ureas. The unusual CH···Cl(-) hydrogen bond is apparent in solution by large (1)H NMR chemical shifts and by a short, linear contact in the solid state.
|
2022-12-21T10:21:43.865Z
|
213,150,160 |
{
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"ArXiv": null,
"DOI": "10.19030/jbcs.v15i2.10316",
"MAG": "3005085321",
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},
"license": "CCBY",
"status": "GOLD",
"url": "https://clutejournals.com/index.php/JBCS/article/download/10316/10368"
}
|
This case study concerns how the personal behavior of students involved in fraternal organizations is depicted in social media, and how that behavior impacts the organization and its image. The legal and ethical implications of individuals’ behaviors in social media has become a major issue for many organizations. This case follows an example of a fraternal organization and how the governing body must handle the information members post on social media. The mission of many fraternal organizations is to champion or contribute to specific causes. Members’ social media postings may reflect poorly on the organization and may not always align with the principles of the organization. This case examines how those postings impact the organization, and what it can do to mitigate the effects. The ethical issues that can affect the actions of both the governing body and the members are probed throughout the case.
|
2022-01-27T04:27:45.326Z
|
120,156,690 |
{
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"ArXiv": null,
"DOI": "10.1109/TAP.1964.1138235",
"MAG": "1970118591",
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"url": null
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|
By using the reciprocity theorem, simple expressions are derived for the far-field patterns of normal and parallel dipoles in a plane dielectric slab. The dielectric slab may have a conducting ground plane on one surface. Numerical results are presented in a graphical form to show the effects of the dielectric on the antenna pattern. A dipole array embedded in a radome occupies less space than a conventional parabolic antenna, and the ground plane offers structural support for the radome.
|
2022-07-27T15:12:01.800Z
|
247,445,892 |
{
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"ArXiv": null,
"DOI": "10.33477/kjim.v2i2.2568",
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"license": null,
"status": "CLOSED",
"url": null
}
|
Abstract: The research entitled Concept of Integral Islamic Education According to Mohammad Natsir, aims to find out how the concept of integral education is applied by Mohammad Natsir. This type of research is library research because the data in this study were taken from library materials. This study uses several methods, including: Content, historical and descriptive. The data sources are taken through primary data and secondary data. The results obtained from this study are Mohammad Natsir's thoughts on integral education, which is an educational model that combines Islamic education and general education, this is evidenced by not contrasting the west with the east. Islam only recognizes the antagonism between right and falsehood. Everything that is right is accepted, even if it comes from the west, all that is false will be removed even if it comes from the east. With the creation of integral education, students can prioritize between spiritual and physical. The implementation of Mohammad Natsir's integral education is that the curriculum used is the national curriculum and the religious curriculum. And balance between worldly life and hereafter, balance between physical and spiritual. In public schools, Islamic Religious Education must be included in a balanced manner. Likewise, Islamic boarding schools must also include general education in a balanced way. Keywords: Islamic Education, Integral, Mohammad Natsir Abstrak: Penelitian yang berjudul Konsep Pendidikan Islam Integral Menurut Mohammad Natsir, bertujuan untuk mengetahui bagaimana konsep pendidikan integral yang diterapkan oleh Mohammad Natsir. Jenis penelitian ini merupakan penelitian studi kepustakaan (library research) karena data-data dalam penelitian ini diambil dari bahan-bahan pustaka. Penelitian ini menggunakan beberapa metode antara lain: Content, historis dan deskriptif. Adapun sumber data yang diambil melalui data primer dan data sekunder. Hasil yang diperoleh dari penelitian ini adalah pemikiran Mohammad Natsir tentang pendidikan integral adalah model pendidikan yang memadukan antara pendidikan Islam dan pendidikan umum, ini dibuktikan dengan tidak mempertentangkan antara barat dengan timur. Islam hanya pengenal antagonisme antara hak dan bathil. Semua yang hak diterima, biar pun datangnya dari barat, semua yang bathil akan disingkirkan biarpun dari timur datangnya. Dengan terciptanya pendidikan integral peserta didik dapat mementingkan antara ruhani dan jasmani. Implementasi pendidikan integral Mohammad Natsir itu adalah kurikulum yang dipakai adalah kurikulum nasional dan kurikulum agama. Serta menyeimbangkan antara kehidupan duniawi dan ukhrawi, keseimbangan antara jasmani dan ruhani. Pada sekolah umum, Pendidikan Agama Islam harus dimasukkan secara seimbang. Begitu pula dengan pesantren juga harus memasukkan pendidikan umum secara seimbang pula. Kata kunci: Pendidikan Islam, Integral, Mohammad Natsir
|
2022-07-31T10:00:11.487Z
|
247,425,032 |
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"DOI": "10.18805/ijar.b-4805",
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"license": null,
"status": "BRONZE",
"url": "https://arccarticles.s3.amazonaws.com/OnlinePublish/Final-article-attachemnt-with-doi-B-4805-6089603e9087340b9bdcbbb1.pdf"
}
|
Background: The principal cause of caprine enterotoxaemia is Clostridium perfringens type D which is normally resident in digestive tract and soil in fairly low numbers. Overeating of carbohydrate rich diet or sudden change in diet leads to proliferation of the bacteria and release of lethal toxins in intestine of the host. It causes sudden death in affected ruminants of different ages, though lambs of 3 to 10 weeks of age are highly susceptible. It causes sever enterocolitis with or without haemorrhagic diarrhoea and encephalitis resulting in acute nervous signs with a fatal outcome.
Methods: Thirty goats of different breeds under 1-4 years age and both sex were presented to Veterinary Clinical Complex, Veterinary College and Research Institute, Tirunelveli with the neurological signs and diarrhoea were the subject of study. Faecal samples were collected from all these cases and tested on spot by immunochromatographic test kit to identify the Clostridium perfringens Epsilon toxin (ETX). Blood and serum samples were collected and subjected haemato-biochemical analysis. Peripheral blood smears were also collected to rule out haemoprotozoan infections in all the cases.
Result: Epsilon toxin was detected from faecal samples of 36.6 per cent of the goats. Diarrhoea was the most consistent finding which is due to enterocolitis in acute cases. A significant increase (P less than 0.001) in the neutrophils and leukocytes count and a significant increase (P less than 0.05) in the levels of BUN, creatinine, glucose, ALP and chloride levels were observed. All the cases were treated with sulphadimidine at recommended dose with supportive therapy but no response was reported due to the fatal encephalitis.
|
2022-03-18T00:57:10.505Z
|
38,636,936 |
{
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"ArXiv": null,
"DOI": "10.1109/LMWC.2005.855391",
"MAG": "2131580638",
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|
The measurement results of detection-of-arrival (DoA) of coherent signals using five-port reflectometers and quasi Yagi antennas are presented. The receiver operating at 2.4GHz consists of eight five-port reflectometers and a uniform linear array (ULA) of eight 2.4GHz quasi-Yagi antennas. The DoA is estimated by measuring the phase difference of signals pitched by the antenna array and by using the MUSIC algorithm associated with Spatial Smoothing Pre-processing (SSP). The phase difference is determined using the five-port technique. The measurement results show that the DoA of coherent signals are well estimated with a maximum error of 2/spl deg/. In addition, we also show that it is capable of estimating the time delay and direction of arrival simultaneously using the five-port technique.
|
2022-12-03T03:46:37.883Z
|
144,718,420 |
{
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"ArXiv": null,
"DOI": "10.1177/0887302X8900700207",
"MAG": "2030567935",
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}
|
Young girls' symbolic associations of clothing styles with behaviors and personality traits were studied in relation to developmental factors. The Measure of Attitudes Toward Clothing for Play (MACP) was used to examine how and why four different clothing styles were matched with play activities in Study 1 and traits in Study 2. Ninety-five girls, aged 2 through 10 years in the initial testing, served as subjects for Study 1; 43 of these girls participated in the longitudinal and trait components of the study four years later. Both the cross-sectional and the longitudinal data from Study 1 revealed an increased tendency with age to associate unisexual styles with physically active and aggressive play behaviors. In contrast, girls of all ages, but especially the older ones, tended to associate the frilliest clothing style with doll play. Data from Study 2 revealed a trend for traits related to interpersonal attraction (e.g., concern with appearance and popularity) to be matched with the frilliest dress, while traits related to aggression, strength, and bravery were associated with the most unisexual style (jeans). Additional data suggested that, by middle childhood, females have not only the cognitive flexibility to develop compromise choices but also the ability to interpret clothing imagery using contextual qualifications. The data are discussed in light of a framework exploring gender and clothing imagery, taking into account symbolic, cognitive, and cultural considerations.
|
2022-12-10T19:30:43.318Z
|
41,957,003 |
{
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"ArXiv": null,
"DOI": "10.2139/ssrn.2132004",
"MAG": "2128866018",
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"url": null
}
|
Despite the fact that the distributional impact of innovation has been recognized in the social science literature, hardly any work has been done on the distributional politics of innovation policy. This study offers a first step in this direction as well as asking whether a government’s ideology affects innovation policy from a distributional viewpoint. The paper uses both qualitative case study method and a statistical analysis of government R&D outlays for social purposes in twenty-six countries. In terms of innovation policy, neo-corporatist interest group representation is linked to relatively equitable public R&D investment and left-oriented governments are more likely to invest in social innovation than their rightist counterparts. Nevertheless, governments rarely consider innovation policy in distributive terms. Despite the significant distributional implications of innovation, it remains depoliticized in policy making.
|
2022-12-12T03:52:14.580Z
|
100,266,892 |
{
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"ArXiv": null,
"DOI": "10.1002/AOC.3532",
"MAG": "2462589886",
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"license": null,
"status": null,
"url": null
}
|
Betti base-modified Fe3O4 nanoparticles have been successfully designed and synthesized for the first time through the condensation of Fe3O4 magnetic nanoparticles coated by (3-aminopropyl)triethoxysilane with β-naphthol and benzaldehyde. Their application as a novel magnetic nanocatalyst in the Knoevenagel condensation and also application to immobilization of palladium nanoparticles for Suzuki coupling reactions have been investigated which opens a new field for application of Betti base derivatives in organic transformations. The synthesized inorganic–organic hybrid nanocatalyst has been fully been characterized using Fourier transform infrared, X-ray diffraction, vibrating sample magnetometry, transmission and scanning electron microscopies, energy-dispersive X-ray, wavelength-dispersive X-ray and X-ray photoelectron spectroscopies and inductively coupled plasma techniques. The catalyst was easily separated with the assistance of an external magnet from the reaction mixture and reused for several consecutive runs with no significant loss of its catalytic efficiency. Copyright © 2016 John Wiley & Sons, Ltd.
|
2022-12-15T04:56:47.441Z
|
95,719,929 |
{
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"DOI": "10.2136/SSSAJ1998.03615995006200030011X",
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|
The kinetics of NH 4+ adsorption and desorption were investigated on the natural zeolite clinoptilolite to ascertain its ability to adsorb and release the important plant nutrient N in its NH 4+ form at various pH values and initial NH 4+ concentrations. Kinetics of NH 4+ adsorption were evaluated on the samples using solutions containing 140.1, 280.2, 560.4, and 840.6 mg L -1 of NH 4+-N at pH 4, 5, 6, and 7, equilibrated for 5, 10, 15, 20, 30, 45, 60, 75, 90, and 120 min. Samples for NH 4+ desorption were equilibrated with 70.1, 280.2, 560.4, and 1401 mg L -1 NH 4+-N solution at pH 4, 5, 6, and 7 for 2.5 h, and adsorbed NH 4+ extracted with 2 M KCI for 5, 10, 20, 30, 45, 60, 90, 120, 150, 180, and 300 min. Equilibrium time for NH 4+ adsorption ranged from 60 min for 140.1 mg L -1 initial NH 4+-N concentration at pH 4 to 120 min for 840.6 mg L -1 initial NH 4+-N concentration at pH 7. Desorption was nearly complete in 150 min for low initial NH 4+ concentrations and 200 min for high initial NH 4+ concentrations. Amounts of NH 4+ sorbed increased with increasing pH and initial NH 4+ concentrations. Models evaluated included the first-order kinetics, modified Freundlich, parabolic diffusion, Elovich, and heterogeneous diffusion. All the models adequately described the NH 4+ adsorption process, with r 2 values ranging from 0.955 to 0.999. With the exception of first-order kinetics, they also described the desorption process well, with r 2 values ranging from 0.897 to 0.999, for all pH and initial NH 4+ concentrations. Reaction rate coefficients (k) were calculated from the modified Freundlich model and ranged from 0.134 to 0.193 min -1 for the adsorption process, and 0.129 to 0.226 min -1 for the desorption process. The models indicated that NH 4+ adsorption and desorption by the zeolite was diffusion controlled. Data from this study indicated the potential use of the tested natural zeolite as an NH 4+ adsorbent and a controlled-release NH 4 + fertilizer.
|
2022-12-19T06:22:10.181Z
|
93,166,377 |
{
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"DOI": "10.1080/10426509908037006",
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|
Abstract Symmetric dialkylphosphoryl-S-alkanediyldiisothiouas (RO)2P(O)NHC(=NH)S(CH2)n SC(=NH)NHP(O)(OR)2 (I, R = isopropyl; n = 2–5) have potential coordination sites involving O, P, N and S as donors atoms. For their synthesis, common two-phase reactions between the corresponding diisothiourea derivatives and diisopropyi phosphonate were unsuccessful. Herein we describe a new synthesis for such compounds using diisopropyl chlorophosphonate. Two new bis-phosphorylated alkanediyldiisothioureas with increasing carbon chain (I; n = 3, n = 5) were prepared by this method.
|
2022-12-19T09:19:27.620Z
|
53,024,377 |
{
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"DOI": "10.1109/IVS.2018.8500566",
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|
Vehicular subsystems such as Anti-lock braking (ABS), Traction Control System (TCS) and Electronic Stability Program (ESP) use low-level sensory data to maintain the vehicle’s stability. We show that sharing that information with neighboring vehicles could prevent potential collisions. Towards achieving this goal, we propose extensions to Dedicated Short Range Communication (DSRC)’s Basic Safety Message (BSM) set and propose a controller which can use the transmitted information to avoid collisions with vehicles experiencing in-stabilities. We show the utility of our methodology by using 3 common lane change scenarios under varying road surface conditions. Finally, we demonstrate some limitations of our methodology using similar scenarios.
|
2022-09-11T00:47:25.991Z
|
5,733,709 |
{
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"ArXiv": null,
"DOI": "10.21236/ada131531",
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"license": null,
"status": "GREEN",
"url": "http://www.aaai.org/Papers/AAAI/1983/AAAI83-049.pdf"
}
|
Even after an unambiguous semantic interpretation has been computed for a sentence in context, there are at least three reasons that a system may map the semantic representation R into another form S.
1. The terms of R, while reflecting the user view, may require deeper understanding, e.g. may require a version S where metaphors have been analyzed.
2. Transformations of R may be more appropriate for the underlying application system, e.g. S may be a more nearly optimal form. These transformations may not be linguisticly motivated.
3. Some transformations may depend on nonstructural context.
Design considerations may favor factoring the process into two stages, for reasons of understandability or for easier transportability of the components.
This paper describes the use of Horn clauses for the three classes of transformations listed above. The transformations are part of a system that converts the English description of a software module into a formal specification, i.e. an abstract data type.
|
2022-10-28T01:22:49.799Z
|
235,796,385 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.18565/urology.2021.3.70-74",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
INTRODUCTION
Benign prostatic hyperplasia (BPH), and chronic prostatitis (CP) are considered to be among the most common causes of lower urinary tract symptoms (LUTS) in men. The combination of BPH with CP raises many questions when choosing the right treatment strategy. For a long time, bioregulators isolated from the prostate gland of cattle have been successfully used in the treatment of CP.
OBJECTIVE
to evaluate the effectiveness of bioregulatory peptides, in particular vitaprost, in the treatment of men with benign prostatic hyperplasia and chronic prostatitis.
MATERIALS AND METHODS
The study included 60 patients with BPH and CP, who were divided into two groups of 30 people. In the comparison group (CG), complex therapy with drugs from the group of alpha-blockers and fluoroquinolones was performed. In the main group (MG), a similar complex therapy was performed in combination with vitaprost tablets. The effectiveness of the treatment was evaluated after two weeks (visit 2) and after 4 weeks (visit 3).
RESULTS
In the MG, a more effective reduction in the severity of LUTs and manifestations of the inflammatory process was noted than in the HS. After 2 weeks of therapy in OG, the average score on the IPSS, QOL and NICH-CPSI questionnaires was lower by 2.4 points, 1.2 points and 2.5 points, respectively, the number of white blood cells in the prostate secret was on average 1.5 times less, and Qmax was higher by 1.4 ml/sec. The revealed differences were statistically significant (p<0.05). This trend continued after 4 weeks of therapy.
CONCLUSION
Thus, the use of bioregulatory peptides, in particular the drug vitaprost, in patients with BPH and CP helps to reduce the severity of LUTs and pain in a shorter time, has a positive effect on the dynamics of the inflammatory process, which leads to an improvement in the quality of life of patients in this category.
|
2022-10-31T14:40:51.077Z
|
234,022,690 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.29394/SCIENTIFIC.ISSN.2542-2987.2021.6.19.0.9-20",
"MAG": "3127833542",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
La publicacion del presente numero, esta dirigido al impacto del COVID-19 en la vida humana, desde su irrupcion a partir de diciembre del ano 2019 en la ciudad de Wuhan (China) y su propagacion en America del Sur desde marzo del ano 2020. Para la perspectiva de analisis de todos los ciudadanos suramericanos, nos era imposible esta irradiacion viral, sin embargo, atonitos advertimos desde marzo del ano 2020, cuando un plan sistematico de aislamiento se implemento de manera gradual en cada uno de los paises a nivel global. Las noticias diarias e informes sobre enfermos, recuperados y muertos, generaron dudas sobre dudas y asi se hicieron extensivas con el devenir de los meses hasta la apertura gradual de las actividades.
|
2022-12-02T12:09:02.940Z
|
27,609,584 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1055/S-2007-996082",
"MAG": "1997471093",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Venous thromboembolism is a major cause of mortality and morbidity in patients undergoing orthopedic surgery. In these patients systemic prophylaxis with anticoagulants appears to be the most effective approach to reduce venous thromboembolic events. Low-molecular-weight heparins (LMWHs) are the prophylactic agents of choice in patients undergoing elective hip replacement. However, their use is still associated with a 15% incidence of deep vein thrombosis (DVT); hence, there is a need for potentially more effective agents. Among these, hirudin and other selective thrombin inhibitors have recently been evaluated. The main pharmacologic properties of recombinant hirudin and the clinical trials carried out with this agent in the prevention of DVT in patients undergoing elective hip replacement are reviewed in this article. Overall, the results of these clinical trials are quite promising; they actually indicate that a b.i.d. subcutaneous injection of 15 or 20 mg of recombinant hirudin is an effective and safe prophylactic approach. Hirudin was more effective than unfractionated heparin, given at a low fixed dose, in two clinical trials and of a LMWH in one clinical trial. However, further studies are required to define the role of recombinant hirudin in the prevention of venous thromboembolism in orthopedic surgery patients.
|
2022-12-10T09:17:41.878Z
|
198,319,345 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.15282/IJAME.16.2.2019.22.0509",
"MAG": "2953518095",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Off-road drivers are exposed to a high magnitude of vibration at low frequency (0.5-25Hz), that can cause harm and possibly attribute to musculoskeletal disorder, particularly low-back pain. The suspension seat is commonly used on an off-road condition to isolate the vibration transmitted to the human body. Nevertheless, the suspension seat modelling that incorporates the human body is still scarce. The objective of this study is to develop a mathematical modelling to represent the suspension seat-person for off-road vehicles. This paper presents a three degrees-of-freedom lumped parameter model. A curve-fitting method is used for parameter identification, which includes the constraint variable function (fmincon()) from the optimisation toolbox of MATLAB(R2017a). The model parameters are optimised using experimentally measured of suspension seat transmissibility. It was found that the model provides a reasonable fit to the measured suspension seat transmissibility at the first peak of resonance frequency, around 2-3 Hz. The results of the study suggested that the human body forms a coupled system with the suspension seat and thus affects the overall performance of the suspension system. As a conclusion, the influence of the human body should not be ignored in the modelling, and a three-degrees degree-of-freedom lumped parameter model provides a better prediction of suspension seat transmissibility. This proposed model is recommended to predict vibration transmissibility for off-road suspension seat.
|
2022-12-14T11:05:02.969Z
|
119,905,469 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1121/1.387606",
"MAG": "1990130510",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The forward and backward propagation of harmonic acoustic fields using Fourier transform methods is presented. In particular, the forward propagation of a velocity distribution to obtain a pressure field and the backward propagation of a pressure field to obtain a velocity distribution are addressed. Numerical examples are presented to illustrate the nearfield behavior of the pressure field from complex planar vibrators, e.g,—an ultrasonic transducer or plate, with nonuniform velocity distributions. The numerical results, which were obtained via the use of FFT algorithms, are presented for vibrators which are operating above and below coincidence. These results illustrate the acoustic nearfield as a function of distance from the vibrator. Numerical results are also presented to illustrate the backward projection method. The pressure field of a 3×3 focused array is back projected to obtain the velocity distribution for several cases of interest. These results illustrate the utility of the transform method ...
|
2022-12-20T13:46:04.102Z
|
228,991,449 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.36314/cunori.v4i2.128",
"MAG": "3095346615",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://revistacunori.com/index.php/cunori/article/download/128/201"
}
|
La idea de escribir este artículo, nace del interés de desarrollar una investigación en el Centro Universitario de Sur Oriente, con estudiantes de la Carrera de Administración de Empresas, con el objetivo principal de caracterizar los estilos de aprendizaje de los estudiantes que cursan la carrera; para tal efecto se consideró a una muestra de 204 estudiantes quienes estuvieron dispuestos a participar. Con los resultados alcanzados se pretende, sirva de soporte en la toma de decisiones de las autoridades y profesores que lideran y orientan el proceso de enseñanza en la institución, así como potencializar el desarrollo del aprendizaje y la generación de competencias profesionales en concordancia con la realidad cognitiva particular del estudiantado, para lo cual se utilizó el cuestionario CHAEA, de Alonso Gallego y Honey, de estilos de aprendizaje.
|
2022-01-27T10:18:28.893Z
|
143,743,009 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2753/CSP1097-1467310317",
"MAG": "1993847145",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
As argued above, if we examine each "form of knowledge" within a modern historical context, it seems that we can see a sequentially transformational and coincident historical line that links the material, then the institutional, and then the cultural, while maintaining the sequential development of the linked trends from beginning to end. Even a summary of Lin Yusheng's hypothesis is a continuation of the "mind's" function orientation. This framework, however, must still answer the following question: In the process whereby "forms of knowledge" become intimately connected with transformational events or time sequencing, do they appear in the form of a totalitarian theoretical model, or do they exert their influence in the form of the dispersed role of a discourse? More concretely, in the case of China: When the traditional "forms of knowledge" of modern Chinese intellectuals—for example, the methodology and behavior within the "thought discourses" of the Confucian School—faced the challenge of the West, did they use "a comprehensive theory" to undertake self-adjustment? Michel Foucault raised a query about the role of totalitarian discourse in saying: "At the beginning of any research I expressed a query about these long-established ‘unified’ models. Traditionally, according to these ‘unified’ models we differentiate infinite, repetitive and fecund territories within the discourse. Must we necessarily, on these ‘unities’ which actually are not unities, pile up yet another even more obscure and even more controversial ‘unitary’ model?"
|
2022-02-09T07:20:40.934Z
|
171,001,137 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/004056397303400415",
"MAG": "2333049956",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
have given themselves over to i t . . ." (p. 127). Once again, an interaction is involved, for "to be a member of any community one must become a member" (p. 128). In the case of this community—the Blood Community, as Royce proclaims it —"the individual's acknowledgement of his need for the community is at the same time his confession that he leads a selfcentered rather than a God-centered existence" (p. 133). So his step towards becoming a member of this community is a step out of that "circular predicament" which defines the human condition (chap. 4). This community, furthermore, can be thought of in its relationship to the wider world in diverse ways. S. conceives that relation in a manner structurally parallel to his more programmatic conception of experience itself: "a creative tension involving mutual criticism" (p. 136). Hence, "the Beloved Community expresses.. .judgment on the modern secular world" as part of its very way of being, yet this claim does not end the matter. Conversely, "the secular world is made to function as a prophetic critic of the Beloved Community at least insofar as it is embodied in actual institutions" (p. 137). Without minimizing the necessity for a community to focus men's concerns and to transform our individual human purposes—"the ethical and religious guidance of the Beloved Community is needed if man is not to destroy himself, because he will not admit a limit to his will" (p. 140)—S. nevertheless reminds us that church can retain its own focus only as church-to-world: "my proposal is that the spirit leading into all truth uses the voice of secular society as a means of keeping the institutional forms which embody the Beloved Community from being tyrannized so that they either obscure God or tyrannize men" (p. 138). Such has been, certainly, our shared experience.
|
2022-07-10T05:56:27.721Z
|
252,234,472 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1063/5.0092091",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
A hysteresis phenomenon observed in neon inductive discharge at low gas pressure is investigated in terms of the evolution of the electron energy distribution function (EEDF). Generally, the hysteresis phenomenon has been reported at high-pressure Ramsauer gas discharges. However, in neon plasma, we found that the hysteresis phenomenon occurs even at low gas pressure (5 mTorr). Furthermore, the hysteresis vanishes with an increase in the gas pressure (10 and 25 mTorr). To analyze this hysteresis, the EEDF is measured depending on the radio frequency power. The EEDF at 10 mTorr sustains the bi-Maxwellian distribution during an E–H transition. On the other hand, the EEDF at 5 mTorr changes dramatically between discharge modes. At 5 mTorr, the measured EEDF for the E mode has the Maxwellian distribution due to high collisional heating in the bulk plasma. The EEDF for the H mode has the bi-Maxwellian distribution because collisionless heating in the skin depth is dominant. This apparent evolution of the EEDF causes a nonlinear energy loss due to collisions during the discharge mode transition. Therefore, the plasma can maintain the H mode discharge with high ionization efficiency, even at a lower applied power, which results in the hysteresis.
|
2022-10-21T00:50:44.540Z
|
7,907,031 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1006/JMLA.1998.2610",
"MAG": "2142469360",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract Previous cognitive research on transfer of learning in bilingual participants has used simple tasks such as word learning. In the present study, an analogical transfer paradigm was used to examine transfer of high-level conceptual information between languages. Experiment 1 examined analogical transfer from a single source story to a target problem in the same or in a different language with Spanish–English bilinguals. Experiment 2 exploited the competitive nature of retrieval in analogical transfer using a more sensitive design in which the target problem was preceded by two source analogs suggesting different solutions. Even with a total of 207 participants across the two experiments, transfer was not significantly or substantially affected by the match or mismatch between the languages of the source and target problems. However, in Experiment 2, the competition between alternative source analogs was greater when the languages of the two analogs matched than when they mismatched. These experiments show that the aspects of memory representations important for higher-order processes such as analogical transfer are primarily language-general and that language-specific features play only a minor role when retrieving and applying information relevant to problem-solving.
|
2022-11-26T19:00:25.152Z
|
244,076,998 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/his.14597",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The inception of the National Health Service Bowel Cancer Screening Programme in England in 2006 highlighted the fact that the differential diagnosis between the presence of epithelial misplacement and adenocarcinoma occurring in colorectal adenomas is problematic. The pathology Expert Board (EB) was created to facilitate the review of difficult cases by a panel of three experienced gastrointestinal pathologists. This article describes a review of the work of the EB over a 4‐year period (2017–2020).
|
2022-12-14T03:27:23.587Z
|
52,058,344 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/jssc.201800634",
"MAG": "2888356444",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Phloridzin is one of the major phenolic compounds in apple and has been widely used in medicine for a long time due to its significant biomedical activities. In this article, macroporous resin was used for purification of phloridzin from apple leaves. The HPD-300 resin was selected for the enrichement of phloridzin according to its high adsorption and desorption capacities. The adsorption kinetics and isotherms were constructed on the HPD-300 resin and fitted well to the pseudo-second-order kinetic model and Langmuir model, respectively. Dynamic adsorption and desorption tests were performed on the column packed with HPD-300 resin to optimize the operating parameters. After one round treatment with HPD-300 resin, the purity of phloridzin in the product increased from 11.4 to 50.1% with a recovery yield of 79.3%. Subsequently, preparative high-performance liquid chromatography was employed for the purification of phloridzin. The purity of phloridzin could reach above 98% after further recrystallization with a recovery yield of 75.8%.
|
2022-12-14T17:52:53.170Z
|
10,363,419 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/00004836-199710000-00006",
"MAG": "2091228452",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Fecal incontinence is an under-reported complication of scleroderma. Ten incontinent patients with scleroderma were evaluated through anorectal manometry and compared with 20 incontinent patients without scleroderma who were matched for age and sex as controls. The scleroderma patients had a higher voluntary external anal squeeze pressure, whereas the resting internal anal sphincter pressure was similar to that of the control group. The threshold for rectal sensation in the scleroderma group was significantly less than that in controls. Episodes of fecal incontinence, anal canal length, and maximal tolerable volume were not significantly different between the study groups. The rectoanal inhibitory response was abnormal in 80% of patients with systemic sclerosis but was normal in 70% of the controls. Stool consistency was significantly looser in the scleroderma patients. Treatment of fecal incontinence in scleroderma patients may be successful in many patients using a combination of dietary and pharmacologic manipulation because diarrhea is an important etiologic cofactor superimposed on reduced internal anal sphincter pressure.
|
2022-12-15T00:25:49.992Z
|
213,909,322 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1051/matecconf/202030602003",
"MAG": "3000624809",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.matec-conferences.org/articles/matecconf/pdf/2020/02/matecconf_icmme2020_02003.pdf"
}
|
In order to investigate the vertical dynamic response characteristics of train-track-bridge system on CWR (Continunously Welded Rail) under dynamic load of train on HSR (High-Speed Railway) bridge. Based on the principle of vehicle train-track-bridge coupling dynamics, taking the 32m simply supported bridge of a section of Zhengzhou-Xuzhou Passenger Dedicated Line as an example, the finite element software ANSYS and the dynamic analysis software SIMPACK are used for co-simulation, and bridge model of the steel spring floating slab track and the CRTSIII ballastless track (China Railway Track System) considering the shock absorbing steel spring, the limit barricade and the contact characteristics of track structure layers are established. On this basis, in order to study the dynamic response laws of the design of ballastless track structure parameters to the system when the train crosses the bridge and provide the basis for the design and construction, by studying the influence of the speed of train on the bridge, the damage of fasteners and the parameters of track structure on the train-track-bridge system, the displacement of rail, vertical vibration acceleration and wheel-rail force response performance are analyzed. Studies have shown that: At the train speed of 40 km/h, the displacement and acceleration of the rail and track slab in the CRTSIII ballastless track are smaller than the floating slab track structure, but the floating slab track structure has better vibration reduction performance for bridges. The acceleration of rail, track slab and bridge increases obviously with the increase of train speed, the rail structure has the largest increasement. Reducing the stiffness of fasteners could decrease the vertical acceleration response of the steel spring floating slab track system, the ability to absorb shock can be enhanceed by reducing the stiffness of the fastener appropriately. Increasing the density of the floating slab can increase the vertical acceleration of the floating slab and the bridge, thereby decreasing the vibration amplitude of the system.
|
2022-12-28T18:18:28.948Z
|
120,379,394 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1674-1056/17/6/057",
"MAG": "1975580327",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A combination of the iterative perturbation theory (ITP) of the dynamical mean field theory (DMFT) and coherent-potential approximation (CPA) is generalized to the double exchange model with orbital degeneracy. The Hubbard interaction and the off-diagonal components for the hopping matrix tmnij(m ≠ n) are considered in our calculation of spectrum and optical conductivity. The numerical results show that the effects of the non-diagonal hopping matrix elements are important.
|
2022-02-26T11:40:26.296Z
|
142,660,819 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5860/choice.43-0169",
"MAG": "1554039176",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
Karen Harvey's Reading Sex in the Eighteenth Century: Bodies and Gender in English Erotic Culture is a cogently argued, well researched, and accessible account of the ways erotic discourse shaped eighteenthcentury understandings of gendered bodies. Her book situates erotica within the context of Thomas Laqueur's description of a shift in representation during the eighteenth century from a one-sex to a two-sex model of the human body.(1) But Harvey also challenges Laqueur's thesis, as well as dominant narratives of women's history and masculinity, arguing that multiple discursive shifts resulted from 'synchronic' rather than 'diachronic' changes. Insisting on the multi-vocality of erotic texts and mindful of the space between representation and practice, Harvey sees the representation of bodies as both a 'product of' and a 'screen for and projection of' cultural, social and political discourse.
|
2022-09-12T23:05:11.732Z
|
253,515,021 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.33387/cannarium.v19i2.4458",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://ejournal.unkhair.ac.id/index.php/cannarium/article/download/65-84/pdf"
}
|
Cloves (Syzygium aromaticum, syn. Eugenia aromaticum), in English called cloves, is the aromatic dried flower stalks of Myrtaceae family. Cloves are native to Indonesia. In Indonesia, clove species cultivated is Zanzibar, Siputih, Sikotok, and Ambon. The information value of genetic diversity of the population of clove is one of the important considerations in determining conservation and breeding strategies conducted. Identification of diversity and kinship cloves in Ternate Island has never been so necessary to identify the diversity and kinship population of clove in order to add information. The purpose of this study is to determine the diversity of the types of clover on the island of Ternate and to investigate kinship cloves in Ternate Island. The research was conducted on the island of Ternate and sampling sites in the District of North Ternate, Ternate South, Central Ternate, Ternate Island which took place in March 2016 to May 2016. The method used in this research is descriptive method with direct observation of the object being observed, Direct observation on the plant example in the field based descriptors guide cloves. The parameters observed were 21 morphological characters and 24 agronomic characters. Data analyzed using analysis of variance diversity Bartlett and Dunnet test and kekerabatannya processed using data clustering analysis matrix (cluster analysis) and manufacturing methods dendogram with UPGMA method. The results of this study indicate that discovered 11 types of clover on the island of Ternate in the Village Rua (Ambon Panjang), Tonggole (Bogor, Ambon Gemuk, Pink), Sulamadaha (Zanzibar Pangkal Kuning), Foramadiahi (Rica), Marikurubu (Zanzibar, Afo) , Jan (Posi-posi), Fitu (Bendera), and Loto (Putih) with the diversity of the nature shown in several morphological characters. As well as kinship 11 types of clover which shows a close kinship between clove White (PTH) with Afo clove (AFO) is 99.00% while by far the kinship between clove Rica (RICA) with clove Flag (BNDR) is 54.56% and Posi-posi cloves (PSPS) is p53.82%.
|
2022-11-18T00:38:27.739Z
|
187,157,391 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/INVENTIONS3040072",
"MAG": "2896273336",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
According to UNESCO, cultural heritage does not only include monuments and collections of objects, but also contains traditions or living expressions inherited from our ancestors and passed to our descendants. Folk dances represent part of cultural heritage and their preservation for the next generations appears of major importance. Digitization and visualization of folk dances form an increasingly active research area in computer science. In parallel to the rapidly advancing technologies, new ways for learning folk dances are explored, making the digitization and visualization of assorted folk dances for learning purposes using different equipment possible. Along with challenges and limitations, solutions that can assist the learning process and provide the user with meaningful feedback are proposed. In this paper, an overview of the techniques used for the recording of dance moves is presented. The different ways of visualization and giving the feedback to the user are reviewed as well as ways of performance evaluation. This paper reviews advances in digitization and visualization of folk dances from 2000 to 2018.
|
2022-12-02T11:24:29.154Z
|
120,155,476 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1299/JSME1958.5.745",
"MAG": "1999808161",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A method of predicting the shape of an oil film cavity in the diverging region of a short journal bearing with a circumferential oil groove is presented. The first term of Reynolds' equation was neglected for mathematical simplicity, thus simulating a short bearing. The pressure distribution, load capacity and attitude angle were also discussed. Some numerical calculations were made to predict the shape of the cavity, and some experimental observations were made using transparent bearings to compare with the analysis.
|
2022-12-10T10:54:10.424Z
|
3,335,129 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1600-0501.2009.01836.x",
"MAG": "2105281069",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://lirias.kuleuven.be/bitstream/123456789/266171/3/Van%20Assche%2cQuirynen%202010.docx"
}
|
BACKGROUND
Recently, guided surgery has been introduced and several papers verified its accuracy.
AIM
While those studies reported on the accuracy of the entire procedure, this experiment wanted to make clinicians aware of the amount of the deviation that can already occur during the drilling procedure alone, due to the tolerance of the drill in the drill key.
MATERIAL AND METHODS
Drilling was executed in plexi-glass with a maximal inclination of the drills within the drill keys.
RESULTS
A mean deviation in angulation of 4.7 degrees occurred with a mean horizontal deviation at the implant shoulder of 0.8 mm and 1.8 mm at the apex of 13 mm implant. The deviation was further dependent of the implant length, the distance of the sleeve above the bone and the respective guiding system.
DISCUSSION
Increasing the height of the drill key will minimize the inaccuracy.
CONCLUSIONS
The results from this experiment showed the importance of keeping the drill parallel to the guide in a centric position.
|
2022-12-17T05:04:48.534Z
|
122,704,232 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/PLASMA.1989.166188",
"MAG": "2131601883",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The effects of contaminants on the electrodes of plasma opening switches have been studied. The contaminants introduce backscattered and sputtered neutral atoms into the carbon plasma that is impinging on the cathode. The process has been investigated with the TRIM.SP code. The distribution of density of these neutral atoms from the cathode surface has been obtained and found to be substantial compared to the density of the incident carbon plasma. The dependence of the sputtering yield on the composition of the contaminants has also been studied.<<ETX>>
|
2022-01-27T08:19:24.187Z
|
72,942,731 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5854/JIAPTR.2013.10.25.557",
"MAG": "2098290706",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Postural balance refers to the process of adjustmentfor maintaining the center of gravity of the bodyagainst the base of support while a person is sta -tionary or moves(1). Postural balance is classifiedinto dynamic balance and static balance. Dynamicbalance means balance when a person moves on thebase of support or moves the human due to externalstimuli. Static balance is an ability to stand on thebase of support without swaying(2) and to maintain aposture when the body does not move by placing thecenter of gravity within the base of support. In order to stably maintain an upright standingposition, anterior-posterior stability, medial-lateralstability, and multi-directional stability are required.Exercise strategies to maintain such stability aredivided into ankle joint, hip joint, and foot holdstrategies(3). Ankle joint strategy is a strategy usedwhen sway for balance is small and the base of sup -port is stable. Movement made from ankle jointstrategy transfers to the proximal area, contributingto postural stability maintenance(4). It is in particu -lar a strategy necessary to maintain balance in astatic condition. The hip and ankle joints play animportant role in balance adjustment for physicalstability and loss of balance sense is related to theweakening of muscle strength of the ankle joints(5).When muscle performance of the ankles, which playsa crucial part in balance adjustment for physical sta -bility is lacking, it affects balance(6, 7) and increasesthe risk of a fall. Diverse studies have observed thatmuscle strength of the ankle joints is an importantfactor in balance adjustment and emphasized theimportance of muscle strength of the ankle joints inorder to maintain static balance. Accordingly, this study aims to examine the effectsof ankle joint muscle strength on their posturalsway in a static state after increasing musclestrength of the ankle joints of normal adults, sub -jects of this study, through an exercise to musclestrength of the ankle joints.
|
2022-02-11T09:30:17.345Z
|
24,521,552 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1302/0301-620X.95B4.31080",
"MAG": "2258752767",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We investigated whether an asymmetric extension gap seen on routine post-operative radiographs after primary total knee replacement (TKR) is associated with pain at three, six, 12 and 24 months' follow-up. On radiographs of 277 patients after primary TKR we measured the distance between the tibial tray and the femoral condyle on both the medial and lateral sides. A difference was defined as an asymmetric extension gap. We considered three groups (no asymmetric gap, medial-opening and lateral-opening gap) and calculated the associations with the Western Ontario and McMaster Universities osteoarthritis index pain scores over time. Those with an asymmetric extension gap of ≥ 1.5 mm had a significant association with pain scores at three months' follow-up; patients with a medial-opening extension gap reported more pain and patients with a lateral-opening extension gap reported less pain (p = 0.036). This effect was still significant at six months (p = 0.044), but had lost significance by 12 months (p = 0.924). When adjusting for multiple cofounders the improvement in pain was more pronounced in patients with a lateral-opening extension gap than in those with a medial-opening extension gap at three (p = 0.037) and six months' (p = 0.027) follow-up.
|
2022-09-06T19:17:45.900Z
|
4,948,856 |
{
"externalids": {
"ACL": "N18-1006",
"ArXiv": "1804.06506",
"DOI": "10.18653/v1/N18-1006",
"MAG": "2796932047",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Recently, neural machine translation (NMT) has emerged as a powerful alternative to conventional statistical approaches. However, its performance drops considerably in the presence of morphologically rich languages (MRLs). Neural engines usually fail to tackle the large vocabulary and high out-of-vocabulary (OOV) word rate of MRLs. Therefore, it is not suitable to exploit existing word-based models to translate this set of languages. In this paper, we propose an extension to the state-of-the-art model of Chung et al. (2016), which works at the character level and boosts the decoder with target-side morphological information. In our architecture, an additional morphology table is plugged into the model. Each time the decoder samples from a target vocabulary, the table sends auxiliary signals from the most relevant affixes in order to enrich the decoder’s current state and constrain it to provide better predictions. We evaluated our model to translate English into German, Russian, and Turkish as three MRLs and observed significant improvements.
|
2022-12-16T11:31:44.497Z
|
203,581,137 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/ma12193144",
"MAG": "2975831304",
"PubMedCentral": "6804001"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/1996-1944/12/19/3144/pdf?version=1569491802"
}
|
The main objective of this study was to obtain chitosan functionalized viscose fabric with improved antibacterial properties and washing durability. In this regard carboxyl and aldehyde groups, as binding points for irreversible chitosan attachment into/onto viscose fabric, were introduced by two different pretreatments: 2,2,6,6-tetramethylpiperidine-1-oxy radical (TEMPO) oxidation and coating with TEMPO oxidized cellulose nanofibrils (TOCN). The Fourier transform infrared spectroscopy, elemental analysis, zeta potential measurements, scanning electron microscopy, breaking strength and antibacterial testing were used to evaluate the influence of these pretreatments on chitosan binding, but also on chemical, electrokinetic, morphological, mechanical and antibacterial properties of pretreated and chitosan functionalized viscose fabrics. Washing durability of chitosan functionalized viscose was monitored through changes in the chitosan content, electrokinetic and antibacterial properties after multiple washing. TOCN coating improves mechanical properties of fabric, while TEMPO oxidation deteriorates them. The results show that both pretreatments improve chitosan adsorption and thus antibacterial properties, which are highly durable to washing. After five washings, the chitosan functionalized pretreated viscose fabrics preserve their antibacterial activity against Staphylococcus aureus, while antibacterial activity against Escherichia coli was lost. TOCN coated and chitosan functionalized viscose fabric is a high value-added product with simultaneously improved antibacterial and mechanical properties, which may find application as medical textiles.
|
2022-12-28T18:12:56.977Z
|
96,427,816 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5829/IDOSI.IJEE.2013.04.03.06",
"MAG": "2055164220",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Bracing elements and their connections have played a key role in the steel bracing frame energy dissipation through yielding and buckling. Whereas it is normally expected that gusset plates yield and buckle after that of bracing elements. Moreover, bracing elements buckling go with the plastic hinge formation in gusset plates. However, the geometry requirement to provide plastic hinge formation leads to larger and consequently thicker gusset plate. This article presents a research concerning steel bracing connection detail. In this proposed steel bracing connection, Hinge Plate manages the formation of the plastic hinge in the bracing connections. To verify the proposed idea a monotonic compression test was conducted on a bracing element; that was detailed with Hinge Plate. As a primary observational goal of the test, buckling mode of bracing element was depicted to be well managed by Hinge Plate. In addition, it was observed that the hierarchy of yielding in bracing element and then in Hinge Plate coincided with expected energy dissipation requirement in bracing frame.
|
2022-02-10T14:28:25.437Z
|
56,239,143 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1051/MATECCONF/201818202017",
"MAG": "2885307766",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The experimental results of the tribo-acoustic control in real time the integrity of nominally stationary friction joints under conditions of fretting are presented. The disturbance in the integrity of the tribosuppression as a result of wear has been reliably detected both by the change in the shape of the acoustic histograms of the operating noise and by the change in the noise spectrum due to the appearance of strong midfrequency modes of the contact gap. The appearance of two oppositely directed wave energy cascades in the regime of fretting has been observed: a direct cascade from mod the pump in the direction of high frequencies and the opposite – side to the low infrasonic frequencies. The former has been associated with microplastic deformations in the zones of actual contact, while the latter has been associated with the dynamic generation of slow angular motions in the friction system.
|
2022-02-11T19:30:34.711Z
|
7,282,950 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICCSE.2014.6926450",
"MAG": "2094658216",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Along with the more and more application of big data mining based on cloud computing in economic life worldwidely, it has also brought revolution to securities industry. This paper firstly reviews the relevant studies on big data, cloud computing and their applications in securities industry, then with the SWOT analysis method, illustrates the strength of big data mining along with the chances it has brought to securities industry, as well as its inherent weakness and challenges facing with securities industry. Then it investigates the status quo and puts forward the related countermeasures for domestic securities industry to develop big data mining. Finally it summarizes the research and proposes outlooks.
|
2022-02-13T09:12:44.032Z
|
210,042,490 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.12122/j.issn.1673-4254.2019.12.11",
"MAG": "3004031110",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
OBJECTIVE
To study the role of Nrf2/ARE signaling pathway in cypermethrin-induced oxidative stress and apoptosis of cerebral cortex neurons in C57BL/6 mice.
METHODS
The cortical neurons of C57BL/6 mice were cultured and identified, and a cypermethrin-induced cell injury model was established by treating the cells with 0, 25, 50 and 100 μmol/L of cypermethrin for 48 h. CCK-8 assay was used to analyze the effects of cypermethrin on the cell viability, and the fluorescence probe DCFH-DA was used for detecting intracellular reactive oxygen species (ROS); flow cytometry was performed for determining the apoptosis rate of the cells. The mRNA and protein expression levels of Nrf2 and its downstream genes HO-1 and NQO1 were detected using qPCR and Western blotting.
RESULTS
Exposure to cypermethrin at different doses inhibited the viability of the cultured cortical neurons. With the increase of cypermethrin dose, the viability of the neurons decreased progressively, the intracellular ROS and the cell apoptosis rate increased, and the neuronal injury worsened. At the dose of 50 and 100 μmol/L, cypermethrin significantly down-regulated the expressions of HO-1, NQO1 and Nrf2 at both the mRNA and protein levels in the cells (P < 0.01).
CONCLUSIONS
Cypermethrin exposure shows a dose-dependent neurotoxicity by inhibiting Nrf2/ARE signaling pathway, down-regulating the expression of Nrf2 and its downstream genes HO-1, NQO1 mRNA and protein, and inducing oxidative damage and apoptosis in primary mouse cortical neurons, .
|
2022-08-28T11:02:40.896Z
|
12,075,189 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/CVR/28.7.1030",
"MAG": "1985442363",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
OBJECTIVES
The aim was to determine whether dobutamine stimulation of energy expenditure within the postischaemic myocardium would affect regional differences in glucose uptake as measured by positron emission tomography (PET).
METHODS
The metabolic rate of glucose uptake within the myocardium can be assessed with the glucose analog 18F-fluorodeoxyglucose (FDG). Stunning was induced in 14 anaesthetised pigs by partially occluding the left anterior descending coronary artery (LAD) for 20 min (> 80% flow reduction). The metabolic rate of glucose uptake was determined 2 h after reperfusion in the LAD and non-LAD regions in two groups: without (group 1; n = 7) and during (group 2; n = 7) a constant intravenous infusion of dobutamine (4 micrograms.kg-1.min-1).
RESULTS
In all pigs, stunning reduced systolic shortening from 16(SD 4)% to 5(5)% (p < 0.05) and slightly lowered myocardial oxygen consumption, from 3.18(1.21) to 2.67(0.93) mumol.min-1.g-1 (p = 0.08). In the postischaemic LAD region of group 1, the metabolic rate of glucose uptake was significantly lower than the non-LAD region (0.11(0.08) and 0.43(0.33) mumol.min-1.g-1 respectively). In group 2, dobutamine induced a sustained increase in both fractional shortening (7(4)% to 16(5)%; p < 0.05) and oxygen consumption (2.34(0.94) to 4.53(1.52) mumol.min-1.g-1; p < 0.05) within the postischaemic LAD region. Despite recruitment of function and oxygen consumption in group 2, the metabolic rate of glucose uptake was similar to that of group 1 (0.11(0.09) and 0.40(0.28) mumol.min-1.g-1 in LAD and remote regions respectively).
CONCLUSIONS
In this pig model of stunning, uptake of FDG was lower in stunned compared with remote myocardium and was independent of postischaemic changes in oxygen consumption and wall thinning. This supports the contention that after stunning, non-glucose substrates play an important part in maintaining energy expenditure during catecholamine stimulation.
|
2022-09-01T05:48:52.613Z
|
46,183,436 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.13005/OJC/310176",
"MAG": "2086578056",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Medicinal plants offer a hope for developing alternate medicines for the treatment of Tuberculosis.. The present study was done to evaluate in vitro anti-tubercular activity of five medicinal plants viz., Syzygium aromaticum, Piper nigrum, Glycyrrhiza glabra, Aegele marmelos and Lawsonia inermis. Solvent extracts of Syzygium aromaticum, Piper nigrum, Glycyrrhiza glabra, Aegele marmelos and Lawsonia inermis were tested in vitro for their activity against Mycobacterium tuberculosis H37Rv strain using Microplate Alamar Blue Assay. Activity in MABA was evaluated by lowest concentration of sample that prevents color change to pink. Extracts of all the five plants Syzygium aromaticum, Piper nigrum, Glycyrrhiza glabra, Aegele marmelos and Lawsonia inermis exhibited anti-tuberculosis activity, the proportion of inhibition of these plants extracts for M. tuberculosis H37Rv, inhibition was found to be 0.8μg/ml, 50μg/ml, 12.5μg/ml and 50μg/ml respectively. Our findings showed that all these plants exhibited activity against MDR isolates of H37Rv M. tuberculosis strain. Further studies aimed at isolation and identification of active substances from the extracts needs to be carried out
|
2022-09-06T18:37:48.402Z
|
43,372,673 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1479-828X.1981.tb00904.x",
"MAG": "2002067805",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The value of microsurgery in gynaecology is still debated. While many gynaecologists support the development of microsurgery, some still regard it as an expensive and time-wasting hobby for those that have nothing better to do. Therapeutic advances in medicine are best assessed by the controlled trial method. Exceptions to this type of assessment exist when the therapeutic advance is sufficiently selfevident as to render a controlled trial a waste of time. Difference of opinion would exist on what is self-evident concerning the application of microsurgery in gynaecology. Microsurgery improves the definition of anatomy and the nature of existing pathology; reduces tissue damage during dissection; enables accurate appostion of tubal ends and the use of sutures causing less tissue damage; and facilitates surgical manoeuvres which could not be attempted by macrosurgery. Whether the considerable circumstantial evidence in favour of microsurgery makes a controlled trial unnecessary remains a matter of opinion. A common method of assessing advances in surgical technique is to compare results, such as pregnancy rates, before and after the introduction of the new technique. Most of the publications discussing the results of tubal surgery are in this category, the surgeon claiming that a new or improved technique has been a causal factor in producing a n improved pregnancy rate. This argument has fallacies. Improved pregnancy rates may be obtained by selecting patients who are more suitable for tubal surgery. Even when patients are carefully categorized according to the site and nature of the pathological lesion, the surgeon's subconscious drive for success may lead to bias e.g. by excluding the near hopeless case. Experience teaches the surgeon how to exclude patients with the worst prognosis following surgery. The second fallacy is that improved results after the introduction of microsurgery
|
2022-09-13T15:32:22.204Z
|
1,829,258 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/088532829100500305",
"MAG": "1983575407",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Bacterial adherence on PE catheters inserted into the carotid artery of rabbits was assessed at 5, 30, and 240 min after injection with bacteria of five coagulase-negative staphylococci (CN Staph). These studies revealed that CN Staph adhere onto PE catheters 5 min after injection with bacteria. At 240 min after injection with bacteria almost all catheters were sterile, indicating that initially adherent bacteria on PE catheters disappear with time. EM studies revealed high numbers of platelets and leukocytes and many fibrin
|
2022-12-13T11:48:19.515Z
|
37,491,913 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/CARCIN/11.8.1437",
"MAG": "2136316793",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The most widely accepted metabolic pathway leading to the formation of reactive intermediates from nitrosamines involves enzymatic hydroxylation at the carbon atom alpha to the nitroso moiety. All subsequent steps are non-enzymatic reactions and the final result is the stoichiometric formation of a cationic product and molecular nitrogen. Thus the amount of molecular nitrogen evolved can be used as an indicator of alpha-hydroxylation. The use of doubly 15N-labelled nitrosamines and the detection of 15N2 by MS makes it simpler to measure the extent of alpha-hydroxylation. We have studied the alpha-oxidation of doubly 15N-labelled N-nitrosobutyl(4-hydroxybutyl)amine (BBN) and its metabolite N-nitrosobutyl(3-carboxypropyl)amine (BCPN), two potent urinary bladder carcinogens in animals, within the target organ. Various amounts of 15N-labelled BBN ranging from 0.1 to 5 mumol were incubated at 37 degrees C for 4 h in the isolated rat bladder and the formation of 15N2 was measured by GC-MS. 15N2 production was linear up to 1 mumol and represented approximately 0.1% of the substrate incubated. Time-course experiments showed that 15N2 production was linear over a 6 h incubation period, ranging from 2.16 +/- 0.05 to 4.55 +/- 0.33 nmol/mg urothelial cell protein. 15N-labelled BCPN (1-5 mumol) was also incubated within the rat isolated bladder. 15N2 production from BCPN was approximately 10 times less than that from BBN. The results indicate that, though to a lower extent, the target organ activates 15N-labelled BBN and BCPN through the alpha-hydroxylation pathway.
|
2022-12-16T12:09:01.933Z
|
154,507,862 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/14783363.2012.661134",
"MAG": "2092800541",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Total quality management (TQM) has been successfully applied to industry all over the world, but not rural tourism in China. Therefore, theoretically this study tries to examine why and how TQM theory should be applied in the practice of rural tourism in the context of new rural construction in China. Empirically, the study conducted a survey in An Yi Ancient Village of China checking how rural tourism TQM is applied and what the effects are. The study found out that the application of TQM in rural tourism has positive effects on economical, social and environmental benefits. The study also found that community-led rural tourism cannot fully realize TQM without educated and trained participants and a democratic system, and therefore suggests a comprehensive management system.
|
2022-12-19T08:16:58.139Z
|
44,766,727 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/ES0340533",
"MAG": "1995890294",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Mackinawite, an iron monosulfide, has been shown to be a potential reductant for chlorinated organic compounds under anaerobic conditions. Chlorinated organic compounds are often found with inorganic contaminants. This study investigates the impact of various transition metals on the reductive dechlorination by mackinawite using a readily degradable chlorinated organic compound, hexachloroethane (HCA). Different classes of transition metals show distinct patterns in their impact on the HCA dechlorination: 10(-3) M Cr(III) and Mn(II) (hard metals) decreased the dechlorination rates, while 10(-4), 10(-3), and 10(-2) M Co(II), Ni(II), Cu(II), Zn(II), Cd(II), and Hg(II) (intermediate/soft metals) increased the rates. The tested hard metals, due to their weak affinity for sulfides, are thought to form surface precipitates of hydroxides around FeS under the experimental conditions with these hydroxides hindering the electron transfer between FeS and HCA. Due to their high affinity for sulfides, however, the tested intermediate/soft metals can react with FeS in various ways: precipitation of pure metal sulfides (MS), formation of metal-substituted FeS by lattice exchange, and coprecipitation of the mixed sulfides in a Fe-M-S system. Fe(II), released as a result of the interaction of FeS with intermediate/soft metals, enhances the HCA dechlorination at the doses of 10(-4) and 10(-3) M through sorbed or dissolved Fe(II) species, while Fe(OH)2(s) formed at the higher dose of 10(-2) M also enhances the reductive dechlorination. Rate increases observed in Co(II)-, Ni(II)-, and Hg(II)-amended systems are not simply explained by the formation of pure MS; instead, metal-substituted FeS or coprecipitated sulfides are thought to be responsible for the significantly increased rates observed in these systems.
|
2022-12-21T18:53:54.282Z
|
247,156,845 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/23247096221079192",
"MAG": null,
"PubMedCentral": "8891914"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://journals.sagepub.com/doi/pdf/10.1177/23247096221079192"
}
|
A 35-year-old female with no medical history presented with fever. Laboratory work was normal except for elevated liver function test (LFT): alkaline phosphatase (AP) (296), aspartate transaminase (AST) (343), alanine transaminase (ALT) (378), and international normalized ratio (INR) (1.23). Ultrasound liver was normal. Infectious workup was negative for hepatitis A virus (HAV), hepatitis B virus (HBV), hepatitis C virus (HCV), hepatitis E virus (HEV), cytomegalovirus (CMV), Epstein-Barr virus (EBV), Herpes simplex virus (HSV), and COVID-19. Similarly, autoimmune hepatitis, Wilson, and alpha-1 antitrypsin workup were negative. She reported taking Yogi-Kanthika (ayurvedic-proprietary medicine) on/off for seasonal sore throat, yet RUCAM-score was 2 (unlikely a drug induced injury). Respiratory-viral-panel came positive for adenovirus. With supportive treatment, symptoms and LFT trended down, thus, liver biopsy decision was deferred. We believe this is the first reported case of adenovirus hepatitis in an immunocompetent adult. Hence, we suggest that clinicians should consider a refined differential diagnosis for elevated LFT (that includes adenovirus).
|
2022-12-29T18:08:48.064Z
|
235,457,204 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1742-6596/1940/1/012046",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://doi.org/10.1088/1742-6596/1940/1/012046"
}
|
Dye waste comes from textile, paint, batik and food industries wastes that produces colored liquid waste which is harmful to the environment. For this reason, the research is carried out to find solutions to these problems. This study aims to determine the effect of flow rate on dye absorption using the column method. Adsorption was carried out by langsat shell activated with nitric acid. The flow rate variations used were 1 mL/minute, 2 mL/minute, 3 mL/minute and 4 mL/minute. The results obtained were that the rhodamine B dye absorbed 1.7901 mg/g, the methyl orange dye occurred 6,0827 mg/g, and the methylene blue dye 12,524 mg/g
|
2022-12-30T00:50:49.510Z
|
76,648,581 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2495/BE030031",
"MAG": "2267515855",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A sensitivity analysis scheme for the boundary value problem of the Poisson equation with the help of the Trefftz method is described in this paper. In the present scheme, inhomogeneous terms of Poisson equations are approximated with polynomial functions in Cartesian coordinates to derive the particular solutions. The solution of the problem is approximated with the T-complete functions of Laplace equation and the particular solutions of the Poisson equation. Direct differentiation of the approximate solution leads to the sensitivities. The present scheme is applied to some numerical examples in order to discuss the features.
|
2022-02-11T06:13:49.349Z
|
93,401,485 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/14.2366",
"MAG": "1980876324",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Statistical modeling procedures are presented for representing various conditions in different types of samples and equipment at, or near, the onset of partial discharge (PD). Using multiple-regression techniques it was possible to establish trends in PD behavior in terms of the repetition rate. The latter parameter was chosen as being sensitive to changes near inception, and it is measurable by conventional instrumentation (for example a multichannel pulse-height analyzer). The statistical repetition rate models also can be related to the probability of inception. The probabilistic definition derived complies with the simpler criteria often used in partial-discharge testing. Application of the methods is described by statistical models determined for five examples that include resin-insulated and oil-impregnated systems. Computer analysis showed that a high proportion of the variability of discharge behavior near inception could be estimated from the models: in particular, the effect of voltage in combination with increase in time, insulation thickness, and temperature changes. In addition, the models indicated that characteristic PD patterns are identifiable for resin voids and oil wedges. It is concluded that adoption of statistical techniques could result in the specification of PD inception in terms of probability, thus reducing the difficulties in interpreting the results from commercial tests. >
|
2022-08-31T20:41:10.030Z
|
73,695,700 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2320/MATERTRANS.F-M2012824",
"MAG": "1993965330",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The authors clarified that various cast irons can be hardened by friction stir processing (FSP) in a previous study. However, the high applied tool load was indispensable for obtaining the hardened layer. In this study, the effect of the tool geometry on the applied tool load was investigated for forming the hardened layer by the FSP with a lower applied tool load. As a result, the applied tool load could be reduced by 36% using a concave tool. [doi:10.2320/matertrans.F-M2012824]
|
2022-09-06T23:55:20.039Z
|
157,561,952 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/009102608301200201",
"MAG": "2730389473",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
he idea of voluntarism fits into the field of Public Administration as part of an emerg ing body of theory and research known as coproduction. Coproduction may be defined I M M as performing the work of government directly or indirectly by nongovernment (or not the same government) officials or employees. The work of government is generalized to mean: decision or rule making, resource allocation or financing, planning, service delivery and social control. Direct performance of government functions is actually doing the work by someone for whom the activity is outside of his/her normal occupational pursuits or nor mal employer. Direct performance may be by volunteers or for compensation. Indirect per formance involves helping or assisting by compliance, facilitation, doing one's part, etc. Examples of indirect performance include supplying information to the police, depositing trash in designated containers in public areas, not exposing others to communicable disease, encouraging one's children to adopt appropriate study habits. There are many borderline cases of direct or indirect coproduction. For example, is a Neighborhood Watch program di rect or indirect? It involves direct activities (organized observing, reporting), but is essen tially good citizenship—little more than obeying the law. Another aspect of the subject is concerned with the structures for coproduction. These may be generalized as public and private government. The latter includes informal groups such as voluntary associations, but also legal entities such as neighborhood corporations, homeowners contractual associations or condominiums, and sometimes neighborhood coun cils. The origins of coproduction appear to stem from three sources. First is the historical trad ition in America of voluntary associations used as implementors of the public weal (e.g., watch and ward societies, sectoral road maintenance committees). This flourishing type of activity impressed De Tocqueville at the beginning of the 19th Century. Later, the waves of European immigrants settled in the major cities of America. These groups were unaccus tomed to an active citizen's role and were organized and manipulated by political party lead ers. Subsequently, professional public bureaucracies replaced the political bosses as providers of social and other services. Coproduction never ceased in rural areas, however, through or ganizations such as the Grange and various marketing and producing cooperatives, as well as government-private initiatives through the Agricultural Extension Service. The second and third origins of coproduction are much more tied to the present day. Fiscal stringency resulting from policies such as Proposition 13 have reduced both authority to spend and to tax and have launched governments into endeavors such as "cutback manage ment" and exploration of service and user charges. Finally, there is a condition arising from the combination of having done the service delivery job well in local government coupled with rising expectations of citizens for a personalized approach to needs fulfillment. Required
|
2022-09-15T02:36:58.435Z
|
214,301,322 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/01605682.2020.1718557",
"MAG": "3006667557",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract As project management has become a critical subject in modern-world organisations, Operational Research (OR) needs to incorporate mechanisms to deal with rapid, unplanned changes as well as confusing information and stakeholders with conflicting values. Agile methods are widely used and tested in Software Engineering (SE) to deal with problems of the characteristics above. Because of this, after establishing that both OR interventions, as well as SE developments, have common stages and information evolution, this proposal aims to pose the challenge of applying agility to manage OR projects. Guidelines to adapt Agile Methodologies to OR are proposed, and a case vignette is studied as an initial test. Finally, future lines of work are considered to define how the larger project in which this proposal is embedded will continue.
|
2022-11-10T14:59:27.441Z
|
196,048,806 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.29207/resti.v2i2.268",
"MAG": "2809230651",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://doi.org/10.29207/resti.v2i2.268"
}
|
Stroke merupakan penyakit yang berhubungan dengan aliran darah ke otak. Biasanya, stroke disebabkan oleh adanya pembuluh darah yang pecah atau terhambat oleh gumpalan darah. Menurut data riset kesehatan dasar oleh Badan Litbangkes Kementerian Kesehatan RI (2013), stroke telah menjadi salah satu penyakit mematikan di Indonesia. Salah satu upaya yang dilakukan untuk mencegah stroke ialah dengan membuat sistem yang dapat mendiagnosa penyakit stroke. Berdasarkan penelitian Indraswari (2015), diperoleh hasil bahwa stroke dapat didiagnosis melalui kriteria faktor resiko. Namun, untuk mendapatkan data tersebut, tentunya pasien harus melakukan pengecekan ke rumah sakit atau laboratorium dahulu. Untuk mengatasi permasalahan tersebut, maka penulis membuat sistem pakar yang dapat mendiagnosis penyakit stroke tanpa harus berkonsultasi langsung kepada dokter. Sistem pakar ini mengadopsi kepakaran dari dokter spesialis saraf.. Hasil diagnosis sistem ini berupa jenis penyakit dan persentase nilai probabilitas terhadap penyakit stroke. Setelah dilakukan pengujian black box, didapatkan hasil bahwa seluruh fungsionalitas sistem telah terpenuhi. Lalu, berdasarkan hasil pengujian white box, nilai cyclomatic complexity yang didapatkan setelah dilakukan optimasi kode program adalah 8, hal tersebut menunjukkan kode program metode Dempster Shafer termasuk kode program sederhana tanpa banyak resiko. Tingkat keakurasian sistem pakar adalah 97% sehingga sistem dapat dijadikan alternatif bagi pasien untuk melakukan diagnosis penyakit stroke.
|
2022-01-27T13:11:25.729Z
|
60,591,845 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2166/HYDRO.2009.041",
"MAG": "1974066063",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This work examines various methods for creating empirical equations on the basis of data while taking advantage of knowledge about the problem domain. It is demonstrated that the use of high level concepts aid in evolving equations that are easier to interpret by domain specialists. The application of the approach to real-world problems reveals that the utilization of such concepts results in equations with performance equal or superior to that of human experts. Finally, it is argued that the algorithm is best used as a hypothesis generator assisting scientists in the discovery process.
|
2022-12-14T21:59:26.111Z
|
42,173,722 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/EIC.2013.6554251",
"MAG": "2081582676",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The aim of this paper is to discuss the impact of nanoparticles in epoxy matrix on dielectric parameters in the course of ageing. One of the directions pursued in the development of epoxy resins is the addition of nanofillers which act as efficient barriers for the propagation of electrical trees. In view of the prospects for the potential replacement of currently-used epoxy-based electric insulations with epoxy nanocomposites, it is necessary to know the behavior of such epoxy resins with nanofillers during aging. For this purpose, epoxy nanocomposites were exposed to accelerated aging and changes in dielectric properties were observed. Experimental samples were manufactured from bisphenol-A based epoxy resin for high voltage applications and oxide nanofillers. The volume of nanofiller added into epoxy resin was 1.5 wt %. Sample thickness was of the order of a few hundreds of μm. Complex permittivity (ε), inner resistivity (ρi) and loss factor (tan δ) were measured at temperatures from -153 °C to +167 °C and in the frequency range 10-2 to 106 Hz.
|
2022-12-17T15:10:04.755Z
|
38,862,107 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5644/SJM.10.2.11",
"MAG": "2323150488",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Inspired by the fact that the discontinuous mappings cannot be (Banach type) contractions and cyclic contractions need not be continuous, and taking into account that there are applications to integral and differential equations based on cyclic contractions, a new type of cyclic contraction mappings satisfying an implicit relation that involves a control function for a map in a metric space is originated. As a result, we derive existence and uniqueness results of fixed points for such mappings. We furnish suitable examples to demonstrate the validity of the hypotheses of our results. The results will be applied to the study of the existence and uniqueness of solutions for a class of nonlinear integral equations.
|
2022-01-27T15:42:23.554Z
|
79,452,249 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1136/jnnp-2016-314597.146",
"MAG": "2560500031",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Aims This study investigated verbal learning and memory abilities in manifest Huntington’s disease using the Hopkins Verbal learning Task to determine how and why performance may change over time. Methods Over a five year follow-up period, standard immediate and delayed memory measures as well as learning curves, serial positions curves and clustering scores were examined annually in a group of twenty mild to moderate Huntington’s disease patients. Results Free recall, both immediate and delayed, deteriorated significantly over five years, and compared to normative data impaired semantic clustering, learning curve trajectory and serial position effects were evident from the baseline assessment. While recognition performance appeared relatively intact over time, the significant increase of false positive errors suggested that this was achieved in parallel with an over-inclusive recognition response bias. Conclusion The patterns of longitudinal decline and deviations from normative data reported in the literature implicate continuing impairment of executive function processes in mild to moderate HD. Our data underlines the very gradual nature of verbal memory impairment which suggests that these measures are less suitable for shorter studies, although they remain useful indicators of day to day memory.
|
2022-02-11T04:00:27.447Z
|
224,937,704 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/eco.2255",
"MAG": "3091584324",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Lichens and mosses are among the first organisms to colonize the open bedrock of eastern Georgian Bay, Ontario making them essential for primary soil formation and ecosystem succession, while also providing nesting habitat for turtle species‐at‐risk. However, the slow growing nature of lichen and moss makes them vulnerable to ecohydrological stresses caused by climate and land‐use change. In order to better understand how lichen and moss will respond to stressors, we examined which ecohydrological factors (e.g., near‐surface soil moisture and temperature) control the CO2 exchange of lichen (Cladonia spp.) and moss (Polytrichum spp.) on rock barrens, and the time of year growth primarily occurs. Net ecosystem productivity (NEP) was significantly greater in the wet period of the growing season than the dry, with an estimated difference of 0.7 μmol m−2 s−1 for lichen, 2.9 μmol m−2 s−1 for moss, and 2.5 μmol m−2 s−1 for a moss and lichen mix. These findings indicate that the wet portions of the growing season are critical for growth, while lichen and moss have little to no productivity during the dry period. Our results indicate that near‐surface soil moisture is an indicator of the CO2 exchange of lichen and moss, and this relationship varies among cover types. For the geographical regions where warm, dry conditions are expected to increase in duration and frequency with climate change, lichen and moss NEP will likely decrease, thus limiting the long‐term availability of nesting habitat for turtle species‐at‐risk.
|
2022-03-28T11:08:19.231Z
|
87,893,906 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1096/fasebj.24.1_supplement.421.1",
"MAG": "2292634638",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
HMGCR (EC ) is the rate‐limiting enzyme of the mevalonate pathway, providing substrates for both protein prenylation and biosynthesis of cholesterol. HMGCR is overexpressed in several forms of human neoplasms, but its importance for adrenocortical tumors (ACTs) is unknown. Expression of HMCGR, StAR, TSPO and CYP11B1 in ACT [Adult: 17 adenomas (ACA) and 10 carcinomas (ACC); Pediatric: 13 adenomas (PAD) and 8 carcinomas (PCA)] were assessed by real‐time RT‐PCR. The viability of NCI‐H295 adrenal carcinoma cells upon mevalonate pathway inhibition was tested using a commercial assay and phosphorylation of ERK1/2 was evaluated by immunobloting. In most of ACT, expression of StAR, TSPO, and CYP11B1 was decreased while the expression of HMGCR was increased. Expression of StAR, CYP11B1 and TSPO were significantly lower in ACC than ACA (P<0.05). No differences in the expression of these genes were found between PAD and PCA. The expression of HMGCR and TSPO correlated negatively while a positive correlation between StAR, TSPO and CYP11B1 was observed. Lovastatin decreased the viability of NCI‐H295A cells. Such an effect was not seen upon treatment of zaragozic acid. Treatment with lovastatin produced a progressive decrease in ERK phosphorylation. Conclusions: HMGCR is overexpressed in ACTs and relevant for survival of neoplastic adrenocortical cells. This effect of HMGCR is probably mediated by protein prenylation rather than cholesterol synthesis.
|
2022-07-09T12:05:05.375Z
|
4,756,489 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1053/J.SULT.2008.12.004",
"MAG": "2031481190",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Radiofrequency ablation (RFA) is now increasingly used as a first-line therapeutic modality for small malignant hepatic tumors in many parts of the world. The importance of radiological imaging at follow-up to assess therapeutic effectiveness, presence of complications, and recurrences cannot be overemphasized, as RFA treatment is minimally invasive and locally applied. A broad spectrum of imaging findings obtained by the use of various modalities has been reported by many investigators. In this review, we describe findings, including chronologic changes of the ablation zones, both local and remote recurrences, and complications that occur after RFA of the liver as well as the advantages and disadvantages of the use of each imaging modality for a specific situation.
|
2022-09-08T07:40:38.301Z
|
209,508,511 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4103/sajc.sajc_366_18",
"MAG": "2997788851",
"PubMedCentral": "6956582"
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://doi.org/10.4103/sajc.sajc_366_18"
}
|
Background: Surgical margin is an important prognostic factor for oral cancers (oral squamous cell carcinoma [OSCC]). The correlation of margin with the type of reconstruction has never been studied. Aim: This study aimed to correlate surgical margins with the type of reconstruction. Methods: This was a retrospective study of 410 treatment-naïve OSCC patients. As per the methods of reconstruction, three groups were made when reconstruction was performed using pedicled flap (PF) or local flap, free flap, and primary closure (PC). Statistical Analysis: Chi-square test was used for comparison of margin status as per the method of reconstruction. Mann–Whitney test was used to find the difference between the mean margin width with respect to the type of reconstruction. Results: The overall incidence of close/positive margins was 7.8%. The incidence of close/positive margins was not significantly different in free flap group compared to PF (P = 0.06) or PC (P = 0.835) group. However, there was a significant difference in the incidence of close/positive margins between PC and PF groups (P = 0.021). Whether the reconstruction is performed by the primary surgeon or by a another surgeon, it did not have an impact on adequacy of margins (P = 0.334). Margins were wider when the reconstruction is performed by a different team (P = 0.015) or when reconstruction is performed as compared to PC. Conclusion: Margins are not affected by the type of reconstruction (pedicled vs. free flap) and the team doing reconstruction (same vs. another team). Margins are significantly compromised when a surgeon performs PC himself/herself compared to PF.
|
2022-11-25T00:53:27.226Z
|
199,538,338 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4103/jdds.jdds_23_19",
"MAG": "2966283624",
"PubMedCentral": null
},
"license": "CCBYNCSA",
"status": "GOLD",
"url": "https://doi.org/10.4103/jdds.jdds_23_19"
}
|
Here, we report a rare case of isolated cutaneous epithelioid hemangioendothelioma (EHE) occurring on the nose of a 56-year-old female patient, without any systemic involvement. This article will also briefly highlight the clinical, pathological, as well as the molecular features of EHE.
|
2022-12-03T22:20:46.449Z
|
9,951,400 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1159/000343395",
"MAG": "2127821405",
"PubMedCentral": null
},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://www.karger.com/Article/Pdf/343395"
}
|
Primary cardiac hemangioma is a very rare benign vascular tumor, with valvular hemangiomas being even less frequent as valves are generally avascular structures. We present the first case of mitral valve hemangioma in a renal transplant recipient. Patient presented with progressive dyspnea. Transesophageal echocardiogram (TEE) demonstrated a 0.8x0.9-cm pedunculated tumor mass on the posterior leaflet of the mitral valve. Coronary angiography identified a small artery which filled from the circumflex artery and fed the tumor. The tumor was surgically removed. Histopathological examination revealed a hemangioma. The postoperative course was uneventful with stable graft function.
|
2022-12-09T01:52:14.974Z
|
138,030,319 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4028/www.scientific.net/MSF.824.77",
"MAG": "2240589279",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Floor screed with different amount of pozzolanic admixture was studied. There were designed 3 mixtures with different amount of the pozzolana. The basic physical properties, mechanical properties and frost resistance were determined. The water /cement coefficient was decided to be taken according to the consistence of the mortar. The mixtures were designed with respect to their application as screed. The properties of developed low-cost pozzolanic screed exceeds the reference material.
|
2022-12-15T05:52:01.672Z
|
97,952,447 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5806/AST.2012.25.6.350",
"MAG": "2063354004",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
To determine ionic species in snowpit samples using ion chromatography system, we described the performance of ion chromatography(IC) system, cleaning method of bottle, and interference by filtering procedure. The limit of detection, reproducibilities, and accuracies determined with BCR ® -408 were 0.01-0.26 μg/L, 0.4-17.4%, 4.5-12.0% for cations and 0.02-0.26 μg/L, 0.1-27.6%, 1.3-5.6% for anions, respectively. Lab blank test for sample bottle indicated that CH₃CO₂ ?, HCO₂ ?, and NH4 + can be easily contaminated in the lab environment. The positive interferences of NO₃ ? were partly attributed to the cleaning method of bottle. The filtering of melted snow sample should be carefully applied because it can positively affect the concentration levels of some ionic species. Finally, this method was applied to measure ionic species in snowpit samples from the upward area near NEEM camp and the uncertainties of measurement data of F? were also estimated.
|
2022-12-16T21:26:40.800Z
|
9,995,565 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1083/JCB.133.2.359",
"MAG": "2132887866",
"PubMedCentral": "2120792"
},
"license": null,
"status": null,
"url": null
}
|
Plakoglobin is the only protein that occurs in the cytoplasmic plaques of all known adhering junctions and has been shown to be crucially involved in the formation and maintenance of desmosomes anchoring intermediate-sized filaments (IFs) by its interaction with the desmosomal cadherins, desmoglein (Dsg), and desmocollin (Dsc). This topogenic importance of plakoglobin is now directly shown in living cells as well as in binding assays in vitro. We show that, in transfected human A-431 carcinoma cells, a chimeric protein combining the vesicle-forming transmembrane glycoprotein synaptophysin, with the complete human plakoglobin sequence, is sorted to small vesicles many of which associate with desmosomal plaques and their attached IFs. Immunoprecipitation experiments have further revealed that the chimeric plakoglobin-containing transmembrane molecules of these vesicles are tightly bound to Dsg and Dsc but not to endogenous plakoglobin, thus demonstrating that the binding of plakoglobin to desmosomal cadherins does not require its soluble state and is strong enough to attach large structures such as vesicles to desmosomes. To identify the binding domains and the mechanisms involved in the interaction of plakoglobin with desmosomal cadherins, we have developed direct binding assays in vitro in which plakoglobin or parts thereof, produced by recombinant DNA technology in E. coli, are exposed to molecules containing the "C- domains" of several cadherins. These assays have shown that plakoglobin associates most tightly with the C-domain of Dsg, to a lesser degree with that of Dsc and only weakly with the C-domain of E-cadherin. Three separate segments of plakoglobin containing various numbers of the so- called arm repeats exhibit distinct binding to the desmosomal cadherins comparable in strength to that of the entire molecule. The binding pattern of plakoglobin segments in vitro is compared with that in vivo. Paradoxically, in vitro some internal plakoglobin fragments bind even better to the C-domain of E-cadherin than the entire molecule, indicating that elements exist in native plakoglobin that interfere with the interaction of this protein with its various cadherin partners.
|
2022-12-18T05:25:36.694Z
|
122,405,880 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/0022-3727/7/6/304",
"MAG": "2123602935",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A technique is presented which enables the recovery of the probability distribution for single scattering from plural-scattering electron energy loss data. Neither the scattering parameter t/? nor details of the component processes need be known. The computational method uses Fourier series in order to overcome a number of practical problems in the application of convolution series methods, to include instrumental effects and to permit the processing of data with large values of the scattering parameter. The effects of noise, specimen oxidation and the accuracy of the technique are considered.
|
2022-12-20T09:54:32.377Z
|
10,275,190 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/chem.201402567",
"MAG": "2021371807",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Altertoxins I-III, alterlosins I and II, alteichin (alterperylenol), stemphyltoxins I-IV, stemphyperylenol, stemphytriol, 7-epi-8-hydroxyaltertoxin I, and 6-epi-stemphytriol are mycotoxins derived from perylene quinone, for which the absolute configuration was not known. Electronic circular dichroism (ECD) spectra were calculated for these compounds and compared with measured spectra of altertoxins I-III, alteichin, and stemphyltoxin III and with reported Cotton effects. Specific rotations were calculated and compared with reported specific rotations. The absolute configuration of all the toxins, except for stemphyltoxin IV, could thus be determined. The validity of the assignment was high whenever reported ECD data were available for comparison, and the validity was lower when the assignment was based only on the comparison of calculated and reported specific rotations. ECD spectra are intrinsically different for toxins with a biphenyl substructure and for toxins derived from dihydroanthracene.
|
2023-01-01T18:36:14.196Z
|
62,663,246 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S0952675700001731",
"MAG": "2068201797",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In English, a number of rules affect the realisation of a nasal consonant or a segment adjacent to a nasal consonant. These include rules of Anticipatory Nasalisation, e.g. bean /bin/ [bĩn]; Coronal Stop Deletion, e.g. kindness /kajndnes/ [kãjnnes]; Nasal Deletion and optionally Glottalisation, e.g. sent /sent/ [set] or [set'] (see Malécot 1960; Selkirk 1972; Kahn 1980 [1976]; Zue & Laferriere 1979). These rules, characterised largely on the basis of impressionistic data, are widely assumed to be phonological rules of English. Yet current views of the relationship between phonology and phonetics make the distinction between phono-logical rules and phonetic ones less automatic than once assumed and a reconsideration of the status of these rules is warranted. In the present article, I use phonetic data from English to investigate these rules. Based on these data, I argue that Anticipatory Nasalisation results from phonetic implementation rather than from a phonological rule, as previously assumed. It is shown that the basic patterns of nasalisation in English can be accounted for straightforwardly within a target-interpolation model. I then investigate the phonological status and phonetic realisation of Nasal Deletion, Coronal Stop Deletion and Glottalisation. The interaction of these rules yields some surprising results, in that glottalised /t/ [t'] is amenable to nasalisation.
|
2023-01-01T21:15:26.832Z
|
172,121,056 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.24246/J.SW.2017.V33.I2.P128-145",
"MAG": "2777534031",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Penelitian ini bertujuan untuk mengembangkan model pembelajaran co-op co-op berbantu Teknologi Inforamsi dan Komunikasi (TIK) pada mata pelajaran Ekonomi. Jenis penelitian yang digunakan dalam penelitian ini adalah penelitian pengembangan (Research and Development). Model pengembangan yang digunakan adalah 10 langkah dari Borg and Gall yang dibatasi pada lima langkah, yaitu identifikasi potensi dan masalah; pengumpulan data atau informasi; desain produk; validasi; dan revisi. Hasil penelitian menunjukan bahwa model pembelajaran co-op co-op berbantuan TIK terdiri dari lima langkah utama, yaitu persiapan, pengembangan, implementasi, evaluasi, dan revisi. Khusus pada langkah implementasi, terdapat sembilan langkah dalam sintak pembelajaran co-op co-op yang berbantuan TIK. Model ini telah dinyatakan layak oleh validator materi dan validator media. Oleh karena itu, disarankan kepada penelitian selanjutnya untuk menguji coba model ini secara empirik dengan penelitian tindakan (action research) atau penelitian eksperimen.
|
2022-01-27T09:46:34.268Z
|
18,140,322 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/PEAM.2011.6135049",
"MAG": "2536579967",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In practice, there are many defects that underground load model is built by using the traditional static load model in coal mine. To enhance the accuracy of load model, a new clustering method based on improved PSO algorithm is presented in this paper. This new clustering method is used to classify the load data in order to reduce the number of load model before modeling. Then, RBF neural network based on improved PSO algorithm is proposed to establish aggregate load model. Verified by an example, compared with traditional static load model, the method in this paper can greatly improve the accuracy of the model.
|
2022-02-13T00:02:53.970Z
|
110,422,384 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.19026/RJASET.7.886",
"MAG": "2183437066",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The aim of this study is to explore to prepare software testers for a platform shift. Doing software testing in cloud environments offers economies and scalability possibilities that are intriguing to software development companies and departments. Interest is high because purveyors of "the cloud" promise to reduce software development and testing expenditures while maintaining or increasing the Quality of Service (QoS). Do those claims hold up? That's what we'll explore in this study.
|
2022-09-02T12:37:07.860Z
|
38,727,868 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/00003086-200212000-00037",
"MAG": "1979856153",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Stair climbing may be detrimental to cemented total hip arthroplasties, because it subjects the reconstruction to high torsional loads. The current study investigated how stair climbing contributes to damage accumulation in the cement around a femoral stem compared with walking, taking into account the different frequencies of these activities during patient functioning. In finite element analyses, the damage accumulation process in the cement mantle around a Lubinus SPII stem was simulated for three different loading histories: (1) isolated walking, representative for patients who climb no stairs; (2) isolated stair climbing; (3) alternating walking and stair climbing in a ratio of nine to one cycles, representative for patients who climb many stairs. Relative to isolated walking, isolated stair climbing increased the amount of cement damage by a factor of 6. Inclusion of 10% stair climbing cycles in the loading history increased the amount of damage by 47% relative to isolated walking. Stair climbing produced damage along the entire stem, whereas isolated walking produced damage proximomedially and around the tip only. This study confirmed that stair climbing is more risky for failure of cemented femoral stems than walking. A few stair climbing cycles during daily patient functioning increases the amount of cement damage dramatically.
|
2022-12-21T17:38:28.053Z
|
154,662,134 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/09654319908720551",
"MAG": "2048302054",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract The hypothesis is put forward in this paper that the innovation activity of a firm also reflects its ability to interact with other partners. It is assumed that innovation intensive manufacturing and service firms, defined by a share of innovation expenditures in turnover of above 3.5%, strongly interact with other partners in the innovation process and that by learning effects, accumulated knowledge and a higher absorption capacity the spatial search radius for potential cooperation partners is increased, resulting in a wide spatial range of networking relations. Using data from a German regional innovation survey, probit models reveal that innovation intensive firms do indeed exhibit a stronger emphasis on interregional networking. Access to external knowledge sources seems to be more important for service than for manufacturing firms, for which a clear knowledge contributing effect of service assistance in the innovation process could not be detected. Interregional differences in networking be...
|
2022-12-21T15:06:37.276Z
|
236,237,079 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.51403/0868-2836/2021/318",
"MAG": "3170791856",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Nghiên cứu cắt ngang mô tả, chọn toàn bộ 712 trẻ gái từ 11 - 13 tuổi, tại 6 trường phổ thông dân tộc bán trú trung học cơ sở, hai huyện Văn Yên và Văn Trấn tỉnh Yên Bái, nhằm mô tả tình trạng suy dinh dương thấp còi và một số yếu tố liên quan. Kết quả trung bình chiều cao trẻ gái 141,2 ± 8,38 (cm), cân nặng 33,9 ± 7,14 (kg). Tỉ lệ suy dinh dương thể thấp còi chung 35,6% (mức độ nặng 12,1%, vừa 23,5%). Tỷ lệ thấp còi khác biệt có ý nghĩa thống kê theo phân nhóm về tình trạng dậy thì, dân tộc mẹ, nghề nghiệp bà mẹ và số con trong gia đình (p < 0,05). Cần tích cực triển khai can thiệp dinh dương cho nhóm đối tượng này để bù đắp cho thiếu hụt phát triển ở trẻ khi còn nhỏ và hiện tại, tạo tiền đề cho trẻ phát triển tốt khi trưởng thành.
|
2022-01-27T04:44:30.908Z
|
2,350,067 |
{
"externalids": {
"ACL": null,
"ArXiv": "1010.1044",
"DOI": "10.1109/ISIT.2011.6033717",
"MAG": "2964307264",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper studies the capacity region of a K-user cyclic Gaussian interference channel, where the kth user interferes with only the (k − 1)th user (mod K) in the network. Inspired by the work of Etkin, Tse and Wang, which derived a capacity region outer bound for the two-user Gaussian interference channel and proved that a simple Han-Kobayashi power splitting scheme can achieve to within one bit of the capacity region for all values of channel parameters, this paper shows that a similar strategy also achieves the capacity region for the K-user cyclic interference channel to within a constant gap in the weak interference regime. Specifically, a compact representation of the Han-Kobayashi achievable rate region using Fourier-Motzkin elimination is first derived, a capacity region outer bound is then established. It is shown that the Etkin-Tse-Wang power splitting strategy gives a constant gap of at most two bits (or one bit per dimension) in the weak interference regime. Finally, the capacity result of the K-user cyclic Gaussian interference channel in the strong interference regime is also given.
|
2022-11-04T00:18:22.254Z
|
147,548,365 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1515/HUMAFF-2016-0011",
"MAG": "2314115030",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract This essay re-considers Karl Mannheim’s notion of democratic behaviour in the context of mass society. Although the term ‘mass society’ seems archaic, it is still the precondition of democracy today. Mannheim conceptualized mass society as irrational, disintegrating Great Society and presented the remedy of Planning for Freedom to counter the crisis of mass democracy. In his remedy Mannheim advocated social education that fosters citizens’ democratic interaction, and the keywords of his education were ‘integrative behaviour’ and ‘creative tolerance’. The similar orientation of his remedy can be found in much more contemporary critiques of deliberative democracy. Iris Marion Young’s ‘communicative democracy’ was a version of her democratic interaction in a complex, large-scale mass society. Young’s notion of ‘reasonableness’ has substantial affinity with Mannheim’s integrative behaviour, both of which require the democratic attitude of hearing the other side and the readiness to self-transform. Mass society theory has relevance for contemporary democratic theory.
|
2022-12-11T01:52:05.055Z
|
195,770,105 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/cells8070660",
"MAG": "2954179537",
"PubMedCentral": "6678974"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2073-4409/8/7/660/pdf?version=1561888335"
}
|
Diabetes-associated advanced glycation end-products (AGEs) can increase extracellular matrix (ECM) expression and induce renal fibrosis. Calbindin-D28k, which plays a role in calcium reabsorption in renal distal convoluted tubules, is increased in a diabetic kidney. The role of calbindin-D28k in diabetic nephropathy still remains unclear. Here, calbindin-D28k protein expression was unexpectedly induced in the renal tubules of db/db diabetic mice. AGEs induced the calbindin-D28k expression in human renal proximal tubule cells (HK2), but not in mesangial cells. AGEs induced the expression of fibrotic molecules, ECM proteins, epithelial-mesenchymal transition (EMT) markers, and endoplasmic reticulum (ER) stress-related molecules in HK2 cells, which could be inhibited by a receptor for AGE (RAGE) neutralizing antibody. Calbindin-D28k knockdown by siRNA transfection reduced the cell viability and obviously enhanced the protein expressions of fibrotic factors, EMT markers, and ER stress-related molecules in AGEs-treated HK2 cells. Chemical chaperone 4-Phenylbutyric acid counteracted the AGEs-induced ER stress and ECM and EMT markers expressions. Calbindin-D28k siRNA in vivo delivery could enhance renal fibrosis in db/db diabetic mice. These findings suggest that inducible calbindin-D28k protects against AGEs/RAGE axis-induced ER stress-activated ECM induction and cell injury in renal proximal tubule cells.
|
2022-12-30T01:14:34.995Z
|
36,472,150 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1600-0404.2010.01451.x",
"MAG": "1950910266",
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://doi.org/10.1111/j.1600-0404.2010.01451.x"
}
|
Constantinescu R, Holmberg B, Rosengren L, Corneliusson O, Johnels B, Zetterberg H. Light subunit of neurofilament triplet protein in the cerebrospinal fluid after subthalamic nucleus stimulation for Parkinson’s disease.
Acta Neurol Scand: 2011: 124: 206–210.
© 2010 John Wiley & Sons A/S.
|
2022-12-30T00:26:00.082Z
|
170,508,818 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3280/SF2010-003002",
"MAG": "1962838570",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In 1582, Carlo Sigonio published a text entitled De Republica Hebraeorum. It used the format of the De repubblica Athenensium manual. The question of the political structure in ancient Israel had already been addressed before, but Siconio was the first to adopt a systematic approach. However, he did not know Hebrew and so used the translation of the Septuagint, giving rise to not a few problems.
|
2022-01-27T03:51:57.445Z
|
71,182,837 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1515/labm.1979.3.2.32",
"MAG": "2005999748",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Die optimale zytologische Beurteilung von Körperflüssigkeiten mit niedrigem Zellgehßlt stellt an die Zellpräparation besondere Anforderungen. Drei Geräte erfüllen solche Anforderungen und sind heute gebräuchlich: Membranfilter, Zytozentrifuge und Sedimentierkammer nach Say k. In der vorliege/.Jen Arbeit werden vergleichend zytologische Untersuchungsergebnisse referiert, die bei Anwendung der drei Methoden gewonnen wurden. Untersucht wurden die Zellen des Liquor cerebrospinatis. Es zeigte sichf daß die weniger gebräuchliche Sedimentierkammer allen anderen Geräten überlegen istf da Morphologie und Färbeeigenschaften der Zelle optimal erhalten bleiben.
|
2022-02-11T11:03:22.964Z
|
25,874,404 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/femsle/fnx126",
"MAG": "2629829151",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://academic.oup.com/femsle/article-pdf/364/12/fnx126/23929522/fnx126.pdf"
}
|
Abstract Toxin‐antitoxin (TA) systems are small genetic elements that are widely prevalent in the genomes of bacteria and archaea. These modules have been identified in various bacteria and proposed to play an important role in bacterial physiology and virulence. However, their presence in the genomes of Actinobacillus species has received no attention. In this study, we describe the identification of four type II TA systems in Actinobacillus pleuropneumoniae, the causative agent of porcine pleuropneumonia. Reverse transcription PCR analysis revealed that the genes encoding the toxin and antitoxin are co‐transcribed. Overexpression of each toxin inhibited the growth of Escherichia coli, and the toxic effect could be counteracted by its cognate antitoxin. The pull‐down experiments demonstrated that each toxin interacts with its cognate antitoxin in vivo. The promoter activity assays showed that each antitoxin could autoregulate either positively or negatively the TA operon transcription. In addition, the APJL_0660/0659 TA system is present in half of the detected serovars of A. pleuropneumoniae, while the others are present in all. Collectively, we identified four type II TA systems in A. pleuropneumoniae, and this study has laid the foundation for further functional study of these TA systems.
|
2022-06-15T07:23:09.820Z
|
110,105,365 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1504/IJTTC.2008.021033",
"MAG": "2158130938",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Many regions around the world have R&D organisations that are developing intellectual property in the field of micro- and nanotechnology. There is a strong desire within these regions to leverage the IP being developed for the overall economic benefit of the region. A number of approaches have been tried with varying degrees of success. One of the key outcomes of many programmes is to stimulate the development of a thriving regional cluster following such successful models as the Cambridge Phenomenon in the UK. The anticipated result is the development of a vibrant regional economy with high levels of employment and income arising from the cluster. This paper will discuss a number of the elements that are necessary for the formation of successful regional clusters for the commercialisation of MNT.
|
2022-09-07T19:53:12.015Z
|
253,437,115 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/molecules27217631",
"MAG": null,
"PubMedCentral": "9654077"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/1420-3049/27/21/7631/pdf?version=1667812949"
}
|
Protein is one of the essential macronutrients required by all living things. The breakdown of protein produces monomers known as amino acids. The concept of conjugating natural compounds with amino acids for therapeutic applications emerged from the fact that amino acids are important building blocks of life and are abundantly available; thus, a greater shift can result in structural modification, since amino acids contain a variety of sidechains. This review discusses the data available on amino acid–natural compound conjugates that were reported with respect to their backgrounds, the synthetic approach and their bioactivity. Several amino acid–natural compound conjugates have shown enhanced pharmacokinetic characteristics, including absorption and distribution properties, reduced toxicity and increased physiological effects. This approach could offer a potentially effective system of drug discovery that can enable the development of pharmacologically active and pharmacokinetically acceptable molecules.
|
2022-11-25T00:53:19.593Z
|
222,401,642 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/JMEDENT/5.4.422",
"MAG": "2322235306",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
An experimental cage with a revolving turntable is described which permits host preference studies to be conducted in the laboratory and which yields results agreeing with field studies. The size and composition of the test population can be controlled, and conditions standardized, providing advantages over field studies. Using this experimental cage and sticky type traps, it was shown that Aedes aegypti (L.) preferred mice to chicks regardless of the weight ratio, while Culex tarsalis Coquillett only preferred the chicks when their weight was 2× that of the mice, otherwise showing no preference. C. tarsalis was attracted to frogs, toads, and lizards, but preferred mice or chicks. A. aegypti was not attracted to cold-blooded animals.
A freeze trapping technique for the collection of animal odors which enables nonchemical separation of odor from carbon dioxide is described. Using this technique, it was found that chick and mouse odor is attractive to both species of mosquitoes, but that live mice are preferred to mouse odor. Human odor from the forearm is as attractive to A. aegypti as baby chick odor. No attractive odor from frogs or lizards was found. The mosquitoes were unable to distinguish mouse odor from chick odor when present in equal amounts. With all other factors being equal, the mosquitoes preferred whichever odor was the most abundant.
The addition of CO2 to mouse odor increased its attractiveness to A. aegypti . No preference was shown by A. aegypti for either mouse odor plus mouse amounts of CO2 or chick odor phis chick amounts of CO2. The carbon dioxide with the chick odor was released at a rate 2.5× faster than that with the mouse odor. For A. aegypti CO2 is attractive, but once a low threshold level of CO2 is reached the addition of more does not cause increased attraction.
|
2022-12-16T09:53:03.833Z
|
22,492,047 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1834-7819.1997.TB00133.X",
"MAG": "2134726407",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A forty year old female patient developed paraesthesia of the right side of her lower lip following the placement of an extensive pin-retained amalgam restoration in her lower right second premolar tooth. Radiographs indicated that the mental foramen was close to the apex of this tooth and it was assumed that postoperative pulpitis and periapical inflammation had caused the paraesthesia through the effects of pressure on the mental nerve. The paraesthesia resolved following endodontic treatment of the lower second premolar tooth and the patient has had no further signs or symptoms.
|
2022-12-16T20:30:13.870Z
|
46,213,546 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1432-1033.1974.TB03704.X",
"MAG": "2085799721",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Unequivocal demonstration of the incorporation of [14C]cyanate into brain proteins as a carbamyl derivative rather than via decomposition to CO2 is presented; this is based on the isolation of radioactive hydantoins and on the loss of radioactivity on hydrolysis of the hydantoins. The influence of conditions on the extent of carbamylation of brain proteins in vitro by cyanate are presented. The optimum pH is about 7 and the carbamylation is dependent on temperature, concentration and time. There was no detectable difference in the rate and/or extent of cyanate incorporation in vitro between normal and previously carbamylated animals. Experiments in vivo show a linear increase in the carbamylation of brain proteins with intraperitoneal injection of cyanate up to the highest concentration tested (2 μmol/g). The extent of carbamylation increases progressively with repeated injections for about 3 days. After this time with further injections there is increased incorporation, but at a lower rate. Experiments in vivo show that animals who have been previously carbamylated with non-radioactive cyanate incorporate about 25% less cyanate than control animals when given a pulse of [14C]cyanate. Fractionation of the major cell components revealed cyanate incorporation into all fractions but a higher incorporation in the supernatant fraction. When brain was fractionated by differential extraction there was incorporation in all the fractions, including the water, salt and solvent-insoluble residue. Although some differences were detected, additional studies are needed to determine whether carbamylation affects protein turnover. The higher sensitivity of experiments in vivo for discrimination of protein carbamylation is discussed in relation to the present work and to recent work from others.
|
2022-12-18T16:39:41.557Z
|