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{
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"ArXiv": "2112.12150",
"DOI": "10.22323/1.395.0334",
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"license": "CCBYNCND",
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"url": "https://pos.sissa.it/395/334/pdf"
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|
Mini-EUSO is a mission of the JEM-EUSO program flying onboard the International Space Station since August 2019. Since the first data acquisition in October 2019, more than 35 sessions have been performed for a total of 52 hours of observations. The detector has been observing Earth at night-time in the UV range and detected a wide variety of transient sources all of which have been modeled through Monte Carlo simulations. Mini-EUSO is also capable of detecting meteors and potentially space debris and we performed simulations for such events to estimate their impact on future missions for cosmic ray science from space. We show here examples of the simulation work done in this framework to analyze the Mini-EUSO data. The expected response of Mini-EUSO with respect to ultra high energy cosmic ray showers has been studied. The efficiency curve of Mini-EUSO as a function of primary energy has been estimated and the energy threshold for Cosmic Rays has been placed to be above 10 21 eV. We compared the morphology of several transient events detected during the mission with cosmic ray simulations and excluded that they can be due to cosmic ray showers. To validate the energy threshold of the detector, a system of ground based flashers is being used for end-to-end calibration purposes. We therefore implemented a parameterization of such flashers into the JEM-EUSO simulation framework and studied the response of the detector with respect to such sources.
|
2022-12-28T14:52:54.868Z
|
254,099,406 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/jof8121249",
"MAG": null,
"PubMedCentral": "9780836"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2309-608X/8/12/1249/pdf?version=1669974121"
}
|
During investigations of saprobic fungi associated with mango (Mangifera indica) in Baoshan and Honghe of Yunnan Province (China), fungal taxa belonging to the orders Botryosphaeriales, Calosphaeriales, Chaetothyriales, Diaporthales, and Xylariales were recorded. Morphological examinations coupled with phylogenetic analyses of multigene sequences (ITS, LSU, SSU, tef1-α, rpb1, rpb2, β-tubulin and CAL) were used to identify the fungal taxa. A new genus viz. Mangifericola, four new species viz. Cyphellophora hongheensis, Diaporthe hongheensis, Hypoxylon hongheensis, and Mangifericola hongheensis, four new host and geographical records viz. Aplosporella artocarpi, Hypomontagnella monticulosa, Paraeutypella citricola and Pleurostoma ootheca, and two new collections of Lasiodiplodia are reported.
|
2022-12-31T18:59:50.500Z
|
223,400,562 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3760/CMA.J.ISSN.0529-567X.2011.08.018",
"MAG": "3031720368",
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"status": null,
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}
|
侵袭性血管黏液瘤(aggressive angiomyxoma,AAM)是一种少见的、病因不明的、好发于中青年女性盆腔和会阴,且具有局部侵袭而无转移的软组织肿物.该病发病率低,文献多为个案报道,故临床易误诊.北京协和医院近10年来,共收治8例外阴阴道AAM的患者,现结合文献复习对其临床特点、病理变化及相关治疗和预后进行探讨。
|
2022-01-27T02:24:23.903Z
|
11,919,994 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.6004/JNCCN.2013.0085",
"MAG": "1818645676",
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},
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"status": null,
"url": null
}
|
Rising costs of cancer care and the growing burden of cancer in a world of finite resources seem to make rationing in oncology inevitable. Information is currently lacking about oncologists' strategies in responding to resource constraints and the prevalence of withholding costly treatments. An online survey was offered via e-mail to physician members of the German Society of Hematology and Oncology. Those actively practicing were asked to complete an online questionnaire asking how limited resources were currently affecting their clinical practice. Two-thirds of 345 participating oncologists reported withholding costly treatments in at least some instances. Regarding their rationale, 70% stated that evidence for costly intervention was not convincing enough, and 59% said that they rationed approved treatments because of an unfavorable cost/benefit calculation. Only 29% reported being explicit about their rationing decision if the patient did not know or inquire about the respective intervention. Withholding expensive procedures from individual patients was widespread among the respondents. Oncologists withheld treatments not only if they perceived the scientific evidence to be questionable but also if they perceived reimbursement prospects or the cost/benefit ratio to be unfavorable, a behavior that could be called rationing. Currently this mostly refers to costly procedures with limited additional benefits. Although this result may be interpreted as indicating that oncologists assume responsibility for spending the resources in a justified way, more transparency and an open discussion on cost-effectiveness and the just allocation of costly treatments is needed.
|
2022-11-14T04:26:16.512Z
|
12,590,270 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1128/jb.144.2.630-640.1980",
"MAG": "1857899874",
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},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc294711?pdf=render"
}
|
Enterobacteriaceae cells growing in liquid media shed fragments of their outer membranes. These fragments, which may constitute a biologically important form of gram-negative bacterial endotoxin, have been reported to contain proteins, phospholipids, and lipopolysaccharides (LPS). In this study we compared the sizes of LPS molecules in shed membrane fragments and outer membranes from cells growing in broth cultures. Using conditional mutants of Salmonella typhimurium which incorporate specific sugars into LPS, we analyzed radiolabeled LPS by sodium dodecyl sulfate-polyacrylamide gel electrophoresis. This technique revealed that S. typhimurium LPS are more heterogeneous than previously known; molecules possessing from 0 to more than 30 O-chain repeat units were identified in outer membranes, supernatant fragments, and purified LPS. The size distributions of LPS molecules in outer membranes and supernatant fragments were similar; supernatant fragments appeared to be slightly enriched in molecules with long O-polysaccharide chains. Our results indicate the LPS molecules of many sizes are synthesized, translocated to outer membranes, and released into culture supernatants. Since the hydrophilic O-polysaccharides extend from bacterial surfaces into the aqueous environment, our findings suggest that the cell surface topography of this bacterium may be very irregular. We also speculate that heterogeneity in the degree of polymerization of O-antigenic side chains may influence the interactions of the toxic moiety of LPS (lipid A) with host constituents.
|
2022-12-14T21:25:53.227Z
|
30,086,634 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/JSAC.2009.090508",
"MAG": "2151922086",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this paper we consider the interconnection of an IEEE 802.15.4 body area network (BAN) in which nodes sense physiological variables such as electrocardiography (EKG), electroencephalography (EEG), pulse oximeter data, blood pressure and cardiac output, with an IEEE 802.11b room/ward WLAN. We model the operation of this two-tier network assuming that 802.15.4 BAN operates in CSMA-CA mode and that the BAN coordinator acts as the bridge which conveys BAN packets to the 802.11b access point. We analyze the two-hop network delay and discuss the mutual interaction of different data streams as well as impact of the number of bridges on packet delay.
|
2022-12-17T09:36:08.128Z
|
16,357,542 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1145/180139.181176",
"MAG": "2041268952",
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},
"license": null,
"status": null,
"url": null
}
|
I show that the linear threshold functions are polynomially learnable in the presence of classification noise, i.e., polynomial in <italic>n</italic>, 1/ε, 1/δ, and 1/&sgr;, where <italic>n</italic> is the number of Boolean attributes, ε and δ are the usual accuracy and confidence parameters, and &sgr; indicates the minimum distance of any example from the target hyperplane, which is assumed to be lower than the average distance of the examples from any hyperplane. This result is achieved by modifying the Perceptron algorithm—for each update, a weighted average of a sample of misclassified examples and a correction vector is added to the current weight vector. Similar modifications are shown for the Weighted Majority algorithm. The correction vector is simply the mean of the normalized examples. In the special case of Boolean threshold functions, the modified Perceptron algorithm performs <italic>O</italic> (<italic>n</italic><supscrpt>2</supscrpt>ε<supscrpt>−2</supscrpt> ) iterations over <italic>O</italic>(<italic>n</italic><supscrpt>4</supscrpt>ε<supscrpt> −2</supscrpt>ln(<italic>n</italic>/(δε))) examples. This improves on the previous classification-noise result of Angluin and Laird to a much larger concept class with a similar number of examples, but with multiple iterations over the examples.
|
2022-12-19T22:32:55.905Z
|
91,261,214 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.19084/RCA17185",
"MAG": "2890985194",
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"license": null,
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"url": null
}
|
Due to the high water use in rice irrigation at the main producing regions of Brazil, it is necessary to test and develop new water-saving cropping systems. The alternate wetting and drying (AWD) system is promising in terms of maintaining productivity levels and water savings. In addition to grain yield, grain quality should be considered, as it is important for commercialization. This study aimed to evaluate the effect of moderate soil water deficiency at different phenological stages of three rice cultivars, on rice grain quality. The experiment was installed in randomized blocks design, with split‑plots and four replications. Treatments consisted on the following soil water levels (Factor B): (1) flooding; (2) saturated (0 kPa) but no flooding; (3) water tension up to 10 kPa; and (4) water tension up to 40 kPa. The crop developmental stage in which these water levels were applied was subdivided into three stages (Factor A): vegetative; reproductive initial and reproductive final. The whole, broken and streaked grains, chalky kernels and chalkiness were analyzed. There are no negative effects of water deficits up to 40 kPa applied to soil, at any phenological stage of rice, on grain quality of rice cultivar developed for continuous flood irrigation.
|
2022-12-23T01:58:58.890Z
|
221,099,371 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/syn.22185",
"MAG": "3048970593",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Aging is a complex process that can lead to neurodegeneration and, consequently, several pathologies, including dementia. Physiological aging leads to changes in several body organs, including those of the central nervous system (CNS). Morphological changes in the CNS and particularly the brain result in motor and cognitive deficits affecting learning and memory and the circadian cycle. Characterizing neural modifications is critical to designing new therapies to target aging and associated pathologies. In this review, we compared aging to the changes occurring within the brain and particularly the limbic system. Then, we focused on key natural compounds, apamin, cerebrolysin, Curcuma longa, resveratrol, and N‐PEP‐12, which have shown neurotrophic effects particularly in the limbic system. Finally, we drew our conclusions delineating future perspectives for the development of novel natural therapeutics to ameliorate aging‐related processes.
|
2022-12-30T18:41:56.468Z
|
197,868,360 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.28927/sr.373277",
"MAG": "2995602831",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://doi.org/10.28927/sr.373277"
}
|
Large-scale mining operations generate vast quantities of tailings that are deposited in hydraulic-fill tailing dams in the form of slurries. Stability of these impoundments require investigation of water table configuration, aquifer boundaries, site characterization and determination of short and long term properties of tailings. These aspects are evaluated in this paper from a comprehensive site investigation that comprises both laboratory and field tests from a bauxite tailing deposit in northern Brazil. The purpose is to enhance the understanding on the mechanical properties of bauxite tailings in order to select or develop appropriate constitutive models for predicting the behavior of tailings impoundments. Attention is given to the characterization and classification of silt tailings from the combination of measurements from independent tests expressed on the basis of the ratio of the elastic stiffness to penetration tip resistance.
|
2022-07-04T09:49:39.466Z
|
200,069,768 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.17509/HISTORIA.V10I2.12222",
"MAG": "2963937117",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Ciomas in this study is an area located in the slope of Gunung Salak, Bogor regency (Buitenzorg) (Besluit. No. 7 year 1882). During the administration of Governor General Herman Willem Daendels, the northern part of this area had been sold to a private party, with the status of the land as private. The extent of the area was about 9.000 bau or approximately 7.220 ha (1 bau = 0,8 ha). As the consequence of the status, the government’s authority over the land in Ciomas became limited compared to the authority over the government’s land. On the other hand, the authority of the private land (landeigenar) owner of Ciomas—who was called the landlord (landheer), over the local inhabitant was ‘almost’ unlimited. According to the regulation of the private land, the land owner has special rights, which was usually held by the government. In the colonial archive, the land owner was called “landlord” by the people and the government. It is different from the concept of landlord in the time Western Europe feudalism. However, in certain terms, there are similarities, including the special rights. This can be understood, regarding that Netherland who gave birth to VOC, was a feudal country.
|
2022-08-01T01:58:09.864Z
|
158,426,614 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5547/01956574.39.2.SFLE",
"MAG": "2787152081",
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},
"license": null,
"status": null,
"url": null
}
|
A total of 29 U.S. states and the District of Columbia have in place mandatory Renewable Portfolio Standards (RPS) which require that a minimum amount of energy come from renewable resources. We investigate the role of hydropower vis-a-vis other renewables under RPS. Using a Bayesian multilevel model, we find that hydropower plants subject to RPS are more likely to plan upgrades. These planned upgrades appear to be a substitute for solar and wind rather than complementary reserve generation.
|
2022-08-20T15:45:45.818Z
|
233,331,687 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ACCESS.2021.3072646",
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},
"license": null,
"status": null,
"url": null
}
|
This paper proposes a novel fault classification method with application to induction motors, which is based on integrating and combining with receiver operating characteristic (ROC) curve and t-distribution stochastic neighbor embedding (t-SNE). According to the feature selection methods of ReliefF, symmetrical uncertainty (SU), and fast correlation-based filter (FCBF), the significant features were verified. Additionally, support vector machine (SVM), k-nearest neighbor (KNN), and decision tree (DT) are also considered as classifiers to identify the simulation results. To begin with, the current signals obtained from distinctive four topologies of working conditions of the motor, which includes healthy, bearing damage, broken rotor bar, and short circuit in stator windings, respectively. The potential feature set is extracted by using Hilbert-Huang transform (HHT) technique. Then, three feature selection methods are adopted to select three optimal feature subsets from the original feature set. Finally, the classification accuracy (ACC) and ROC curve are used to demonstrate the capability of classifiers’ recognition. The results showed that the optimal feature subsets significantly reduce the number of selected features and improve the classification ACC and area under the curve (AUC) compared with the original feature set. In conclusion, the proposed method can downgrade the data, demonstrate the scatter plot more intuitively, and identify various types of faults, unlike with other fault diagnosis literature.
|
2022-12-13T03:56:10.535Z
|
2,149,324 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1046/J.1523-1755.2001.059002804.X",
"MAG": "1993196935",
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|
illicit drugs. He had not noted any peri-orbital or leg edema, shortness of breath, chest pains, hematuria, or urinary symptoms. His only medication was fosinopril, 10 mg orally each day. The physical examination revealed a well-developed white male in no apparent distress. The blood pressure was 146/ 84 mm Hg; pulse, 84 beats/min; respiratory rate, 16 breaths/ min; temperature, 98.68F; weight, 215 lbs; and height, 599′′. The physical examination was unremarkable. Ultrasound tests showed an atrophic 3.4 cm echogenic right kidney, and a 12.6 cm left kidney with normal echogenicity. Laboratory evaluation revealed: serum glucose, 97 mg/dL; cholesterol, 137 mg/dL; triglycerides, 672 mg/dL; albumin, 4.1 g/dL; total protein, 7.4 g/dL; hematocrit, 46%; platelets, 361,000/mm; serum creatinine, 1.2 mg/dL; BUN, 15 mg/dL; and normal electrolytes. Creatinine clearance was 126 mL/min. An open renal biopsy disclosed early lesions of focal segCASE PRESENTATIONS mental glomerulosclerosis (FSGS) and glomerulomegaly, charPatient 1 acteristic of secondary FSGS (Fig. 1). The renal changes most A 13-year-old white boy was noted to have proteinuria, likely were related to his unilateral renal atrophy. He was 1 g/24 hr, eight years ago on a routine physical examination treated with a higher dose of the same ACE inhibitor. At latest for participation in school sports. The serum creatinine and follow-up nearly two years later, the serum creatinine was blood glucose levels were normal, and serologic tests were 1.2 mg/dL, and proteinuria was ,500 mg/24 hr. negative. Ultrasound examination demonstrated a very small, atrophic right kidney and hypertrophy and normal echogenicity Patient 2 of the left kidney. A diagnosis of solitary functioning kidney A 5-year-old white girl presented 17 years ago with an 8was made. month history of relapsing nephrotic syndrome. The first two The patient was treated with dietary protein restriction and episodes were steroid-sensitive, but subsequent relapses were an angiotensin-converting enzyme (ACE) inhibitor. At routine steroid-dependent, and she was admitted for renal biopsy. Labfollow-up at age 19, the proteinuria had increased to 3.7 g/24 oratory tests revealed normal serum creatinine (0.8 mg/dL), hr, and he was referred for further evaluation. The medical hypoalbuminemia (0.8 g/dL), proteinuria (2 g/24 hrs), negahistory was significant for a bilateral inguinal hernia repair at tive ASO titers, and normal complement levels. Physical exage 10 months, and a poorly documented history of vesicoureamination showed 31 edema, and her blood pressure was teral reflux as a child. The family history was significant for 120/70 mm Hg. microhematuria detected in the father three months prior to The renal biopsy showed no segmental sclerosis in the 23 this evaluation, a maternal grandmother with hypertension, glomeruli sampled. Immunofluorescence studies were negative, and a paternal grandfather with diabetes. There was no family and electron microscopy showed extensive foot process effacehistory of visual abnormalities or hearing loss. No hypertension ment. An initial diagnosis of minimal change disease was made. had been noted at regular follow-ups. The patient had gained Corticosteroid treatment was continued with no response even 25 pounds over the previous 18 months. A college student, he at a higher dose (40 mg daily). Addition of a six-week course worked part-time in an ice cream store. He had smoked for of chlorambucil resulted in remission (serum albumin, 4.3 g/dL; one month one year previously and did not drink alcohol or use proteinuria, 420 mg/24 hr). She remained in remission for 18 months and had a normal serum creatinine (0.3 mg/dL) when she was 7 years old. She then had a relapse following an upper
|
2022-12-20T15:32:21.800Z
|
20,770,671 |
{
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"DOI": "10.1109/3DTV.2011.5877192",
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|
A novel hardware implementation of an omnidirectional image sensor is presented which is capable of acquiring and processing 3D image sequences in real time. The system consists of a hemispherical arrangement of a large number of CMOS imagers, connecting to a layered arrangement of a high-end FPGA platform that is responsible data framing and image processing. The hardware platform in charge of real-time processing the 3.8 Gb/s data which is generated by the cameras is presented, and a first application of the system consisting of omnidirectional image acquisition is demonstrated.
|
2022-11-17T18:21:15.223Z
|
244,913,846 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.51889/2021-3.1728-7847.01",
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|
This article presents the results of a study of the development of professional competence of future education managers. The relevance of the problem under study lies in the demand for education managers in educational institutions. The personal and behavioral characteristics of future managers were studied using the SAMOAL test-questionnaire for diagnosing self-actualization of personality. The formation of the main professional competencies was determined by expert assessments of employers - school directors with many years of experience.
|
2022-01-27T13:19:22.996Z
|
84,714,082 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1117/12.945397",
"MAG": "1997726863",
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"license": null,
"status": null,
"url": null
}
|
The interactions of calf thymus DNA with the chemotherapeutic drug cis-diamminedichloroplatinum (II), and with the clinically ineffective trans-isomer, have been studied by time-dependent fluorescence depolarization of intercalated ethidium. The effect of binding these compounds on the flexibility of DNA has been determined by monitoring the rapid internal torsional and bending motions of the DNA via depolarization of the ethidium fluorescence. The depolarization data are analyzed with an elastic model of DNA dynamics and yield an estimate of the torsional rigidity of DNA. Binding of the cis-isomer to DNA has a pronounced effect on the torsional rigidity, causing increased rigidity at low binding levels and decreased rigidity at high levels. These results are discussed in terms of intrastrand cross-link formation and local melting of DNA duplex-structure. The torsional rigidity of DNA is unaffected by binding of the trans-isomer. The possible relevance of these alterations of DNA flexibility to the selective drug action of the cis-isomer is considered.
|
2022-02-11T00:04:19.706Z
|
209,371,087 |
{
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"ArXiv": null,
"DOI": "10.1177/096032719401301010",
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|
The purpose of this section in Human and Experimental Toxicology is to draw attention to papers that are of significance to toxicologists but may be missed because, in the main, they have not been published in mainstream toxicology journals. In addition the papers selected attempt to reflect topics of the liveliest current research interest as well as those which impinge upon the professional practice of toxicology. In order to assist the assimilation of such new material an expert commentary is provided and because these aim to focus succinctly on the advance made they should also serve as mini-reviews to keep us all abreast of our rapidly developing, multi-disciplinary, subject.
|
2022-07-08T04:09:35.101Z
|
2,780,489 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1109/AICCSA.2011.6126613",
"MAG": "1999070545",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper presents a comparison between DMPML and three data mining applications (Weka, RapidMiner, and KN-IME) that implement the directed graph approach, concerning the time spent to create and execute the data preparation tasks for two data mining algorithms. The tests were executed using different types of data sets: numerical, categorical, and mixed. We observed that the scheme used by the DMPML framework can simplify the usage of different data mining algorithms and reduce the time spent creating the data preparation tasks.
|
2022-07-21T21:03:15.681Z
|
248,777,199 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1002/elps.202100390",
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"status": null,
"url": null
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|
Dynamic single‐drop microextraction (SDME) was automatized employing an Arduino‐based lab‐made Cartesian robot and implemented to determine parabens in wastewater samples in combination with liquid chromatography–tandem mass spectrometry. A dedicated Arduino sketch controls the auto‐performance of all the stages of the SDME process, including syringe filling, drop exposition, solvent recycling, and extract collection. Univariate and multivariate experiments investigated the main variables affecting the SDME performance, including robot‐dependent and additional operational parameters. Under selected conditions, limit of detections were established at 0.3 µg/L for all the analytes, and the method provided linear responses in the range between 0.6 and 10 µg/L, with adequate reproducibility, measured as intraday relative standard deviations (RSDs) between 5.54% and 17.94%, (n = 6), and inter‐days RSDs between 8.97% and 16.49% (n = 9). The robot‐assisted technique eased the control of dynamic SDME, making the process more feasible, robust, and reliable so that the developed setup demonstrated to be a competitive strategy for the automated extraction of organic pollutants from water samples.
|
2022-08-03T06:30:02.311Z
|
93,235,028 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1039/C29690000478",
"MAG": "1988915234",
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},
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"url": null
}
|
The solvent isotope effect on the ketonization of acetone enol demonstrates the similarity of this reaction and the hydrolysis of enol ethers.
|
2022-08-31T20:36:25.341Z
|
108,933,307 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2514/3.28373",
"MAG": "2331684454",
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}
|
An assessment of the differences seen in static vs flight testing of solid rocket motors has been evaluated to provide the designer with better data, and the currently available nondestructive testing, static, and flight test instrumentation has been identified and discussed, along with the most promising new approaches for use during flight testing. These new approaches are microwave horns, ultrasonics, thermovision, in situ transensors, and isotopes, along with a parachute recovery concept to confirm postfiring flight test results. The major aspects of the problems with these concepts are addressed and a preliminary estimate of the development problems, time, and funding requirements are presented.
|
2022-09-08T23:24:07.914Z
|
252,912,650 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/eurheartj/ehac544.1784",
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"license": null,
"status": "BRONZE",
"url": "https://academic.oup.com/eurheartj/article-pdf/43/Supplement_2/ehac544.1784/46361651/ehac544.1784.pdf"
}
|
Transthyretin cardiac amyloidosis (ATTR-CM) is a progressive and fatal cardiomyopathy. Treatment options in patients with advanced heart failure are limited to cardiac transplantation (CT). Despite small case series demonstrating comparable outcomes with CT between patients with ATTR-CM and non-amyloid cardiomyopathies, ATTR-CM is considered to be an absolute contraindication to CT in some centres. This is in part due to a perceived risk of amyloid recurrence in the cardiac allograft. We report outcomes of patients with ATTR-CM assessed at our centre whom underwent CT over the past thirty years.
We retrospectively evaluated all ATTR-CM patients assessed at the UK National Amyloidosis Centre between 1990 and 2020 who underwent CT. Pre-transplantation disease and patient characteristics were determined and outcomes were compared with our large cohort of non-transplanted ATTR-CM patients. Censor date was 11th January 2022.
Eleven (9 male, 2 female) patients with ATTR-CM underwent CT including 8 with wild-type ATTR-CM and 3 with variant ATTR-CM (ATTRv). Median age at CT was 60.3 years and median follow up post-CT was 65.7 months. Median (range) NT-proBNP concentration pre-transplant was 4478ng/L (1057–8778ng/L), median (range) left ventricular ejection fraction (LVEF) was 39% (27–56%) and mean (IQR) interventricular septal (IVSD) was 18 mm (15.9–20.1 mm). 8 patients were NYHA functional class III, the 3 remaining patients were class II.
One, three, and five-year survival was 100%, 89% and 86%, respectively and the longest surviving patient was censored >19 years post CT. Survival is at least comparable to UK and US CT outcome registry data for all non-amyloid patients undergoing CT. No patients had recurrence of amyloid in the cardiac allograft as assessed by endomyocardial biopsy and/or Tc-DPD scintigraphy. Two patients were commenced on Patisiran for amyloid polyneuropathy at 211 and 5 months post-CT. Graft rejection requiring treatment was observed in 2 patients, and successfully treated with intravenous steroids. Renal impairment was common, with 6 patients being left with chronic kidney disease.
Three patients died, including one with ATTRv-CM from complications of leptomeningeal amyloidosis. Survival among the cohort of patients who underwent CT was significantly longer than UK patients with ATTR-CM generally (P≤0.006), regardless of NAC ATTR disease stage and including those diagnosed under 65 years of age (P=0.028). (Figure 1) All surviving patients were NYHA functional class I at time of censor.
Our data indicates that cardiac transplantation is well tolerated, restores functional capacity, and prolongs survival in ATTR-CM with little risk of recurrence of amyloid in the cardiac allograft. We believe that our data argues strongly for ATTR-CM to be routinely included in the list of indications for cardiac transplantation.
Type of funding sources: None.
|
2022-12-16T10:41:36.388Z
|
202,781,135 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1109/TCSVT.2019.2938038",
"MAG": "2970200245",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this paper, we propose a novel channel pruning method for convolutional neural network (CNN)-based trackers. Pre-trained CNNs are widely used in visual tracking to obtain high-level representations of targets. However, most pre-trained CNNs are trained for other tasks (e.g., VGGNet is trained for image classification), and they require a considerable amount of time to generate features. First, we introduce a dimensionality reduction method considering the information amount and tracking errors to obtain good low-dimensionality features from the last convolutional layer for tracking. Then, a backward channel selection method is proposed to select representative channels layer by layer. In this process, we aim to minimize the target changes and maximize the loss of the background or other objects. Finally, we reconstruct the neural network weights to reduce the information loss of the target with one-shot learning. Experimental results on challenging benchmarks show that the proposed channel pruning method can enhance the tracking performance and reduce the computational requirements.
|
2022-12-22T15:36:55.285Z
|
103,987,656 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/00032719.2017.1298118",
"MAG": "2712566714",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
ABSTRACT A novel strategy to improve the sensitivity of molecularly imprinted polymer sensors based on a double-layered molecularly imprinted polymer hybrid film-modified gold electrode was investigated for the determination of testosterone. A conductive poly(anilinomethyltriethoxysilane) film was electrodeposited on the surface of the electrode, and a molecularly imprinted polysiloxane thin film was formed on the conductive layer by a sol-gel process to enhance the electrochemical response. The performance of the sensor for testosterone was investigated by square-wave voltammetry in the presence of a hexacyanoferrate/ferrite as a redox probe. The prepared sensor provided high recognition for testosterone with a broad linear range from 10 to 100 fM and a low detection limit of 10 fM. Good sensitivity, selectivity, and stability were observed with relative standard deviations less than 5%. Good recovery of testosterone was obtained when the sensor was used for the determination of testosterone in fortified urine.
|
2022-12-25T22:58:54.931Z
|
19,212,701 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/1471-0528.15273",
"MAG": "2802509055",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://obgyn.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/1471-0528.15273"
}
|
Doctors, like everyone else, must listen to their consciences. Those who provide abortion are motivated by compassion. Our conscience will not let us turn away from women in distress. Many of us had a religious upbringing. If we had decided at the start of our training never to talk to these patients, we might never have developed a conscience about them. This article is protected by copyright. All rights reserved.
|
2022-03-25T01:22:30.810Z
|
211,060,827 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICEEIE47180.2019.8981418",
"MAG": "3005383866",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Mental health problems are increasingly crucial in the workplace. These issues affect employee productivity and accordingly it affects the company's prolificacy. To minimize mental health issues among employees, companies must identify factors related to employee's mental health. Therefore, a classification method to find out whether an employee requires mental health treatment or not is highly much-needed. This paper seeks to develop the application of features selection using chi-square to the performance of the K-Nearest Neighbor (KNN) algorithm in conducting classifications. The stages carried out were: (1) collecting data obtained from Open Sourcing Mental Illness (OSMI), (2) data preprocessing process (data cleaning, feature selection, data transformation), (3) implementing the KNN algorithm in classifying the data, and (4) evaluation process to determine algorithm performance outcome using a confusion matrix which generates precision, recall, and accuracy values. The classification using the KNN algorithm obtained 87.27% of accuracy, 84.21% of precision, and 66.7% of recall. Accordingly, the resulting performance is more effective than previous research. The 2.27% increase in accuracy compared to the research conducted by Shruti Appiah in conducting classifications using Naive Bayes and SVM resulted in an accuracy of 66%. To sum up, data on mental health treatment is applicable for classification using KNN with a high degree of accuracy.
|
2022-09-30T01:57:13.642Z
|
252,222,126 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/DCR.0000000000002477",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
BACKGROUND
The European Crohn's and Colitis Organization guidelines have highlighted the importance of the preoperative evaluation of the affected segment length to determine the best surgical approach.
OBJECTIVE
We evaluated the accuracy of preoperative magnetic resonance enterography in assessing the length of the affected segment in patients with an ileocolic Crohn's disease.
DESIGN
We conducted an observational study with a prospectively maintained database and retrospective analysis.
SETTINGS
This study was conducted in a tertiary center.
PATIENTS
We included consecutive patients undergoing ileocolic resection for Crohn's disease between August 2014 and June 2020. All patients underwent a preoperative magnetic resonance enterography.
MAIN OUTCOME MEASURES
The correlation between the length measured on magnetic resonance enterography and pathological examination was evaluated.
RESULTS
A total of 96 patients were included. Median time between magnetic resonance enterography and surgery was 65.5 (3-331) days. The length of the affected segment on magnetic resonance enterography was correlated with the length assessed on pathological evaluation (R = 0.48, p < 0.001). There was no correlation between the 2 measurements when imaging was performed more than 6 months prior to surgery (R = 0.14, p = 0.62). The presence of an abscess underestimated the length affected by Crohn's disease on imaging when compared to pathology while the presence of a fistula was associated with magnetic resonance enterography overestimation of the length of the affected segment.
LIMITATIONS
Limitations included single center study, and retrospective analysis.
CONCLUSION
In Crohn's disease, preoperative magnetic resonance enterography is a highly reliable tool for predicting the length of the affected segment when compared to pathology examination, in the absence of abscess or fistula. See Video Abstract at http://links.lww.com/DCR/C26.
|
2022-12-11T11:57:10.617Z
|
40,535,722 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1136/archdischild-2013-304689",
"MAG": "1982882047",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
> Trust your hunches. They’re usually based on facts filed away just below the conscious level.
> James Joyce (1882–1941)
Child protection is one of the most challenging aspects of paediatric practice. The consequences of missing a case of serious abuse are self-evident, with one child dying every week as a result of deliberately inflicted injury, abuse or neglect; indeed recently released data identified this as the single largest category of childhood deaths with modifiable factors in England.1
Clinicians working in this field need the most sophisticated diagnostic, communication and team working skills and great personal resilience to deal with the emotional demands of the work. Despite this, the role has often been undervalued and poorly supported, with some viewing it as a ‘Cinderella specialty’. The stress on clinicians has also been exacerbated by high-profile media cases in which paediatricians have been vilified in the press, both for missing diagnoses and conversely for making positive diagnoses which have subsequently been overturned in court.
From a public perception, there is a view that medicine is based on a robust body of evidence, with little tolerance for error, or understanding of the fact that diagnosis is actually the art of making a best estimate based on probabilities. This is particularly the case for child protection, in which the evidence base has been slow to emerge and forms only part of the picture. Hence, diagnosis is dependent on the trigger of an initial index of suspicion, supported by a mix of corroborative detail, experience, triangulation, monitoring, review and above all the highest level of multiagency communication and cooperation.
Fortunately, there is a slow but steady change in status and perception of the specialty, in large part due to clearer guidance and better multiprofessional working. Alongside this, the gradual emergence of a more robust evidence …
|
2022-01-27T13:05:11.403Z
|
61,813,347 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21305/ismpp2013.001",
"MAG": "2186546774",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "http://www.healthsciencelive.com/uploads/UK/936740_UK_poster_246.pdf"
}
|
Objective:�Systematicreviewsareincreasingin� popularityowingtothetransparent,�unbiasedand� reproduciblemeansbywhichtheyreviewpublished� data.�Byvirtueoftherigoroussearchtechniquesthey� employ,�systematicreviewscanbemoretime-consuming� toproducethanotherpublications.�Here,�weused� bibliometricstoevaluatewhethertheaddedinvestment�� isreflectedbyahighimpactontheliterature. Research design and methods: Allsystematic� reviews,�narrativereviewsandprimarymanuscripts� acrossthreeclientaccountspublishedinpeer-reviewed� journalsbetween�2003�and�2011�wereincluded.�Each� paperwasauthoredby,�receivedprofessionalmedical� writingsupportfrom,�orwascoordinatedbywritersat� OxfordPharmaGenesis ™ .�Ananalysisofallcitationsof� eachpaperwascarriedoutusingGoogleScholar�(April� 2012).�Thetimesincepublicationandnumberofcitable� yearswerecalculatedforeachpaper.�Currentimpact� factorsofthepublishingjournalswerecapturedusing� JournalSelector�(Sylogent,�Pennsylvania,�USA).� Results: Weanalysed�125�papers�(31�systematic� reviews,�14�narrativereviewsand�80�primary� manuscripts).�Meancitationspercitableyearwere� 11.0 forsystematicreviews,�4.1�fornarrativereviews� and�4.9�forprimarymanuscripts.�Systematicreviews� were,�ingeneral,�publishedinhigh-rankingjournals;� meanimpactfactorofpublishingjournal:�5.02�for� systematicreviews,�2.10�fornarrativereviews,�3.98�for� primarymanuscripts.�(Please note, citation data have been updated since submission of abstract; updated data reported in the Results section in the main text.)
|
2022-02-11T15:33:57.558Z
|
148,708,710 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4000/dms.1831",
"MAG": "2711674404",
"PubMedCentral": null
},
"license": "CCBYSA",
"status": "GOLD",
"url": "https://doi.org/10.4000/dms.1831"
}
|
Dans sa preface au livre recent Pour comprendre les MOOCs (Depover, Karsenti et Komis, 2017), Pierre Dillenbourg ecrit a propos des Mooc que jamais autant d’acteurs sociaux (medias, universitaires, decideurs et investisseurs) n’ont autant parle d’education et de formation. Cet « effet » Mooc vaut bien evidemment pour la recherche : le « phenomene » Mooc inspire un foisonnement de recherches et d’experimentations, il redynamise la reflexion sur la formation secondaire et tertiaire, formelle ou...
|
2022-03-04T10:31:47.819Z
|
224,993,100 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.30736/JT.V12I2.480",
"MAG": "3088061200",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Berisi halaman judul edisi 12 no.2 September 2020
|
2022-07-10T02:38:35.910Z
|
97,916,464 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1135/CCCC19971754",
"MAG": "2151647069",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A series of arylhydrazones 1a-1i was prepared by coupling of arene diazonium salts with ethyl N-(benzo[ b ]furan-2-yl)carbamate. The hydrazones 1 were thermally cyclized to the corresponding 2-aryl[1]benzofuro[2,3- e ][1,2,4]triazin-3(2 H )-ones 2a-2i , derivatives of a new fused ring system. Compounds 2 were transformed by hydrolytic splitting to the corresponding 1-aryl-5-(2-hydroxyphenyl)-6-azauracils 3a-3i .
|
2022-09-13T23:16:52.164Z
|
109,285,021 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/15732470500424260",
"MAG": "2010397147",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Hydrogen sulfide is a serious problem for many municipalities across North America and worldwide. Odor, safety, and corrosion are the major problems associated with the presence of hydrogen sulfide in sewerage systems. This paper investigates the effect on sulfide generation of using innovative coatings in concrete sewer pipes. A pilot-scale model, consisting of three concrete pipes (each 75 cm in length and 30 cm in internal diameter), was used to simulate the process of sulfide generation in a sewer system. Two of the pipes were internally coated with either cuprous oxide (C.O) or silver oxide (S.O), while the third one served as a control. Each of the oxides was mixed with a commercial epoxy, used for repairing concrete sewer pipes, prior to spraying on the internal surface of the concrete pipe specimens to form a coating film. Test data showed that the sulfide generation by sulfate-reducing bacteria (SRB) in the C.O and S.O coated pipes was reduced by 92% and 100%, respectively, compared with that of the control pipe. The coating films effectively decreased the bacterial count in the nutrient solution. Results also suggested that the slime layer formed in the C.O coated pipe was significantly smaller and thinner compared with that of the control pipe. No slime layer was observed on the internal surface of the S.O coated pipe at the conclusion of the test.
|
2022-09-14T01:17:54.546Z
|
115,523,753 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/EN12071195",
"MAG": "2924780324",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The stability problem of the power system becomes increasingly important for the penetration of renewable energy resources (RESs). The inclusion of electric vehicles (EVs) in a power system can not only promote the consumption of RESs, but also provide energy for the power grid if necessary. As a mobile energy storage unit (MESU), EVs should pay more attention to the service life of their batteries during operation. A hierarchical distributed control strategy was proposed in this paper for mobile energy storage clusters (MESCs) considering the life loss of each EV’s battery. This strategy was divided into a two-layer control structure. Firstly, numerous EVs were divided into different clusters according to their regional relationships. The lower layer adopted a distributed collaborative control approach for allocating energy among EVs in the cluster. Under this condition, an aggregate EVs response model was established and the characteristic of the MESC was analyzed. Secondly, the upper layer applied the multi-agent consensus algorithm to achieve the optimal allocation among different clusters. Therefore, the control strategy realized the two-way communication of energy between EVs and the power grid, and ensured the optimal economical dispatch for the mobile energy storage system (MESS). Finally, the simulation of testing examples verified the effectiveness of the proposed strategy.
|
2022-12-02T10:24:47.316Z
|
220,469,084 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/1471301206071308",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Adler, Geri, Susan Rottunda, Kathy Christensen, Michael Kuskowski and Paul Thuras, Driving SAFE: Development of a knowledge test for drivers with dementia, 5(2), 213–222 Ariss, Steven M.B., Eryk Grant, Murna Downs, Brendon Fernandez, Ruth Gallagher, Debra Cherry and Michelle Barclay, Piloting a consumer-directed intervention to improve primary care for dementia in the UK, 5(3), 456–462 Aubeeluck, Aimee and Heather Buchanan, Capturing the Huntington’s disease spousal carer experience: A preliminary investigation using the ‘Photovoice’ method, 5(1), 95–116 Bailey, Jean and Jo Moriarty, Alzheimer’s Society Derby branch: A comprehensive programme of support for people with dementia and their carers, 5(2), 293–296 Brannelly, Tula, Negotiating ethics in dementia care: An analysis of an ethic of care in practice, 5(2), 197–212 Braudy Harris, Phyllis and John Keady, Editorial, 5(1), 5–9 Cantegreil-Kallen, Inge, Clément Turbelin, Pierre Angel, Antoine Flahault and Anne-Sophie Rigaud, Dementia management in France: Health care and support services in the community, 5(3), 317–326 Cockerill, Rhonda, Susan Jaglal, Louise Lemieux Charles, Larry Chambers, Kevin Brazil and Carole Cohen, Components of coordinated care: A new instrument to assess caregivers’ and care recipients’ experiences with networks of dementia care, 5(1), 51–66 Dartington, Tim, Editorial: Managing vulnerability, 5(4), 475–478 Derksen, Els, Myrra Vernooij-Dassen, Philip Scheltens and Marcel Olde-Rikkert, A model for disclosure of the diagnosis of dementia, 5(3), 462–468 Downs, Murna, Steven M.B. Ariss, Eryk Grant, John Keady, Stephen Turner, Michelle Bryans, Jane Wilcock, Enid Levin, Ronan O’Carroll and Steve de men tia
|
2022-01-23T02:43:32.668Z
|
140,203,318 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1144/qjegh2012-062",
"MAG": "2094397947",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Large suffusion and cover-collapse sinkholes, of up to 100 m in diameter, developed in the Lar valley in Iran. The sinkholes formed through overburden several hundred metres thick comprising coarse- and fine-grained deposits. The formation mechanism for these large sinkholes was studied based on the topography of the bedrock and on deep borehole log data. It could be determined that the large cover-collapse sinkholes are located above permeable bedrock berms and that they formed through a layer of fine-grained, cohesive soil that was both underlain and overlain by coarse-grained soil layers. The data analysis showed that suffusion from the coarse-grained layer at the bedrock and subsequent erosion of these particles through permeable zones in the bedrock to the karst channels caused settlement of these coarse-grained layers and the formation of open caverns above them, at the interface with the fine-grained layer. With continuing erosion, the caverns widened until the limit equilibrium of the fine-grained layer was reached and then collapsed to form a depression with a horizontal bottom surface, termed a cover-collapse sinkhole. An analytical model was developed for this mechanism, considering cohesive and non-cohesive soil layers. This analytical model confirmed that, for the given composition of the overburden, cover-collapse sinkholes of 80–100 m in diameter can be expected. The paper also analysed the formation mechanism of the suffusion sinkholes and it was shown that their formation took place through coarse-grained, non-cohesive formations, in this case alluvium and slope talus. Finally, it was analysed whether the formation of new cover-collapse and suffusion sinkholes after the rehabilitation of the reservoir leakage is likely.
|
2022-10-28T19:10:55.355Z
|
19,797,748 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1755-3768.2009.01800.x",
"MAG": "2157785309",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc2891782?pdf=render"
}
|
Acta Ophthalmol. 2010: 88: 877–884
|
2022-12-20T05:30:30.764Z
|
187,789,206 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/OSO/9780198833444.003.0015",
"MAG": "2945441792",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Focus on a March Dimes Brochure illustrates two statistical measures of risk of neural tube defects at birth contrasting and applying odds ratios and percentages.
|
2022-01-24T18:18:34.256Z
|
203,029,722 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1051/EPN/19871807098",
"MAG": "1621762758",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Historically, the first schemes for dis covering neutron stars were based on the detection of the thermal radiation from a cooling star in the X-ray band. Since neutron stars are the remains of the central cores of massive stars that have consumed all possible internal energy sources, it was natural to as sume that they would be cooling from the moment they were created. Follow ing the advent of X-ray astronomy in the early 1960s with the discovery of the brightest galactic X-ray source Sco X-1 (Giacconi et al. 1962), detailed calcula tions of cooling rates and cooling curves started to appear in the scientific litera ture (for a review see Tsuruta 1986). The hope was to find neutron stars several hundred years old, with surface tempe ratures around several million degrees. Although the general idea was correct, this method of finding neutron stars turned out to be the difficult way. It is ironic that only recently have we been able to detect thermal radiation from cooling neutron stars, after the development of sensitive focusing X-ray instruments — some 12 years after the discovery of neutron stars as pulsars (Hewish et al. 1968). In retrospect, it is obvious that during the collapse to a neutron star, the original magnetic field and the rotation rate of the progenitor star would be amplified by approxima tely the square of the ratio of the initial to final radius ( 1010), and that such ob jects should generate all kinds of elec tromagnetic fields and waves at the ex pense of their rotational energy. In the meantime, the strong X-ray sources discovered five years before the pulsars have also been identified as neutron stars, accreting mass from close binary companions and converting the gravita tional energy gained by the gas to X-rays emitted from the surface. Although this model was suggested back in 1967 by Shklovskii to explain Sco X-1, several years were to pass before the observa tions with the UHURU satellite showed the existence of pulsing X-ray sources which were unmistakably interpreted as rotating and accreting neutron stars. Despite the fact that the radiation emitted from cooling neutron stars has not been the best way to discover them, this information should contribute signi ficantly to our understanding of the in ternal structure of the neutron star. The structure is of topical interest not only for astrophysics, it also provides a uni que opportunity to study the imperfectly understood hadron equation of state at nuclear ( 0 3 x 1014 g/cm3) and higher densities (for reviews see Gor don, Baym and Pethick 1979; Pines 1987; Shapiro and Teukolsky 1983, Chapter 8). Let us start by examining the salient features of a 1.4 solar mass (MO = 2 x 1033 g) "cold" neutron star with "stiff" equation of state, shown in Fig. 1 (from Pines and Alpar 1985). Going from outside to the centre, one encounters first an atmosphere a few meters thick, followed by an outer crust, a few hun dred meters in depth and of density increasing from 7 x 106 to 4 x 1011 g/cm3. The outer crust consists of a solid array of nuclei and degenerate rela tivistic electrons. The next kilometer or so is called the inner crust; it starts with the density 4 x 1011 g/cm3, where the neutrons find it energetically easier to exist outside the nuclei and start dripp ing out, and extends to O, the nuclear density regime. The properties of this region which contains degenerate elec trons, superfluid neutrons, and a lattice of neutron rich nuclei, is reasonably well understood. At deeper layers, going down 10 kilometers to the centre, where densities are in excess of 0 and nuclei start dissolving and merging together, the equation of state is not well known. It is possible, that charged pions are pro duced through n → p + -, for example, and having spin 0, then form Bose-Einstein condensates. At the very extreme densities near the centre, we may even get a relativistic Fermi gas of quarks. This picture of a "cold" neutron star is actually valid for interior temperatures up to 1010 K (1 MeV) since, owing to the high densities involved, the crust mel ting temperature is about 1010 K and the Fermi energies of the quantum liquids are in the 5 x 1011 K to 5 x 1010 K (5 50 MeV) range. Considering that follow ing supernovae explosions, neutron stars are probably born with tempera tures of 1011 K, it should take less than a minute to solidify the crust and establish the superfluid interior. Let us start at this point to examine the cooling of the neutron star. For the pur poses of a first order calculation, let us assume a two component thermodynaFig. 1 — Cross-section of a 1.4 MO neutron star. Figure taken from Pines and Alpar (1985).
|
2022-01-27T04:36:32.086Z
|
126,034,799 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.18576/MSL/060307",
"MAG": "2759540335",
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},
"license": null,
"status": null,
"url": null
}
|
R. Sundareswaran and V. Swaminathan [11], introduced the concept of the domination integrity of a graph. It is a useful measure of vulnerability and it is defined as DI(G) = min{|S|+m(G−S), where S is a dominating set and m(G−S) is the order of a maximum component of G−S}. In this paper we introduce the concept of global domination integrity of a graph G, and define it as GDI(G) = min{|S|+m(G−S), where S is a global dominating set and m(G−S) is the order of a maximum component of G−S}. The global domination integrity of some graphs is obtained. The relations between global domination integrity and other parameters are determined.
|
2022-02-09T16:28:14.566Z
|
80,354,150 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.23751/PN.V19I2.6539",
"MAG": "2734386000",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
La riduzione della mortalita umana e il conseguente allungamento della vita media e un fenomeno che non ha eguali nel mondo, perche e avvenuta a partire dal XX secolo e ha coinvolto solamente le ultime quattro delle circa 8000 generazioni di esseri umani (1-3).
|
2022-02-11T03:11:01.159Z
|
248,434,890 |
{
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"ArXiv": null,
"DOI": "10.1053/j.gastro.2022.04.043",
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},
"license": "CCBYNCND",
"status": "HYBRID",
"url": "http://www.gastrojournal.org/article/S0016508522004565/pdf"
}
|
This assay was performed using a cell-based split luciferase system in which donor cells (human embryonic kidney HEK293 cells expressing SARS-CoV-2 spike and HiBiT) and acceptor cells (HEK293 cells expressing ACE2 and LgBiT) were co-cultured. After 24 h, the luciferase activity associated with fusogenicity was measured. In the experiment with REGN-CoV2, we added antibodies to the cells 24 h before measurement.
|
2022-11-20T18:33:37.206Z
|
141,014,078 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1026//0942-5403.10.3.161",
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"url": null
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|
Zusammenfassung. Leistungsstres ist heute bei Jugendlichen ein weitverbreitetes Phanomen und stellt eine potentielle Gefahrdung der psychischen Gesundheit junger Menschen dar. Die Kontroll-Wert Theorie der Leistungsemotionen (Pekrun, 1992, 2000) beschreibt psychische Entstehungsbedingungen von Leistungsstres bei Jugendlichen: Neben bewusten Situations- und Ressourceneinschatzungen (vgl. Lazarus & Launier, 1978) nach dem Erwartung × Wert-Prinzip wird die bedeutende Rolle automatisierter Bewertungsprozesse betont. Diese liefern einen wesentlichen Beitrag bei der Aufrechterhaltung und Veranderungsresistenz von situativem Streserleben. Es werden Wege aufgezeigt, wie aus bewusten Bewertungen automatisierte Verarbeitungsprozesse im Leistungskontext entstehen, welche negativen Konsequenzen automatisierte Stresreaktionen haben konnen und welchen Einflus das soziale Umfeld, wie zum Beispiel die Eltern, im Jugendalter auf Stresentstehung und -verarbeitung hat. Es werden kognitive und emotions-fokussierte Methoden d...
|
2022-12-13T13:38:17.071Z
|
102,483,154 |
{
"externalids": {
"ACL": "N19-1361",
"ArXiv": "1904.01608",
"DOI": "10.18653/v1/N19-1361",
"MAG": "2950528275",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Identifying the intent of a citation in scientific papers (e.g., background information, use of methods, comparing results) is critical for machine reading of individual publications and automated analysis of the scientific literature. We propose structural scaffolds, a multitask model to incorporate structural information of scientific papers into citations for effective classification of citation intents. Our model achieves a new state-of-the-art on an existing ACL anthology dataset (ACL-ARC) with a 13.3% absolute increase in F1 score, without relying on external linguistic resources or hand-engineered features as done in existing methods. In addition, we introduce a new dataset of citation intents (SciCite) which is more than five times larger and covers multiple scientific domains compared with existing datasets. Our code and data are available at: https://github.com/allenai/scicite.
|
2022-12-28T20:12:22.274Z
|
234,292,212 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.22271/ORAL.2021.V7.I1F.1158",
"MAG": "3133941859",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
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|
Introduction: Prosthodontic care is needed in aging patients as they tend to be most neglected.Aim: This paper intends to highlight the importance of edentulism and its treatment in elderly population.Material and Method: Target population was surveyed and studied.Results: It was seen that geriatric patients require dentures and special prosthesis depending on edentulism and their suitability.Discussion: It is need of hour that considering higher age and dentate state appropriate measures are taken.Conclusion: Prosthodontic care for elderly is a critical subject which needs special effort by the fraternity.
|
2022-01-27T04:52:14.895Z
|
170,569,314 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1515/semi.1982.41.1-4.107",
"MAG": "2080002551",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
For a good two decades we have been hearing about a 'linguistic turn' in philosophy. This turn is based on the thesis that language is not just one more topic of philosophical interest among others, such as nature, history, art, and mathematics, that are dealt with by so-called Ijyphen-philosophies, philosophical disciplines of a second level, but is, as a condition of knowledge in general, the primary object of a prima philosophia. In Germany we have come to use a word that supposedly goes back to Nietzsche to sum up this transcendental role of language, a word for which other languages have trouble finding a concise equivalent. This slogan is that of the Nichthintergehbarkeit der Sprache, 'the nonunderpinnability of language' by nonverbal modes of cognition, as one might tentatively try to translate it. Thus, language has finally received an honor that most of the other topics I just mentioned have received at one time or another, from one philosophical school or another. Think of the philosophies that have promoted Life, History, Art, or Science to the status of the central philosophical theme. And just this fact is enough to make us a bit skeptical. Karl-Otto Apel (1963) went furthest in his now 20-year-old book on the idea of language in the humanistic tradition from Dante to Vico: Language, which cannot be based on nonverbal cognition and which is on the contrary constitutive for our knowledge.of the world, is our particular mother tongue. The categories of thpught thus lose their universality. They are not 'determined once and for all for all men'. They change from one 'historical linguistic community' to the next (1963: 26). In order to explain the happy fact that Japanese are most certainly capable of understanding and thinking productively in terms of Newton's physics and Descartes's philosophy, Apel claims that they must have previously taken over the 'mother tongue of the Western mind', which functions as the metalanguage of modern physics and metaphysics. This view exhibits a wide variety of holes:
|
2022-02-08T17:16:47.720Z
|
79,548,201 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1056/JW200402270000002",
"MAG": "2614881755",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Prevention of influenza became a focus of attention this winter, particularly after the 2003-2004 flu vaccine proved to be less effective than previous formulations. In an international, industry-sponsored study, investigators evaluated the efficacy of the neuraminidase inhibitor oseltamivir (Tamiflu) for preventing the spread of influenza within households.
During the winter …
|
2022-02-11T03:55:56.619Z
|
117,629,612 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1063/1.42310",
"MAG": "1500901951",
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},
"license": null,
"status": null,
"url": null
}
|
This paper is a review of observations of emittance growth in Fermilab accelerators which are not due to coherent effects, but result from beam oscillations excited by external stimuli. Specific examples are presented in order to emphasize the magnitude of the effects which can cause measurable emittance growth.
|
2022-02-09T23:15:36.401Z
|
136,058,728 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/00218464.2017.1301255",
"MAG": "2591694989",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
ABSTRACT A simple method of applying and distributing multi-walled carbon nanotubes (MWCNTs) onto grit-blasted steel substrates has been investigated in this study to overcome the difficulty of mixing MWCNTs in epoxy adhesives forming the MWCNT-reinforced adhesive joints. MWCNTs were dispersed in an acetone and resin (no hardener) solution with the weight ratio of 1:3:100 for MWCNT/resin/acetone, which was then applied onto the grit-blasted steel substrates. After evaporation of acetone, an ultra-thin layer of resin pre-coating kept well-distributed MWCNTs within the micro-cavities created by grit blasting. Epoxy adhesives (with hardener) were then applied to bond the steel substrates to create MWCNTs-reinforced adhesive joints. The results show that the MWCNT pre-coating (PC) method is beneficial to strong adhesive bonding. Most importantly, the MWCNT-PC method can be easily applied for structural applications on site. In the current study, MWCNTs were simply dispersed in the acetone and resin (no hardener) solution by simple rod stirring for around 1 minute, which can be adopted for large-scale applications. Scanning electron microscopy (SEM) observations on fracture surfaces and cross sections of the MWCNT-reinforced adhesive joints showed MWCNT micro-bundles were well dispersed within the epoxy adhesive joints taking the contour of microscopically uneven substrate surfaces.
|
2022-09-15T02:49:19.962Z
|
135,033,788 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.22498/pages.19.2.89",
"MAG": "2790224776",
"PubMedCentral": null
},
"license": "CCBY",
"status": "HYBRID",
"url": "http://www.pastglobalchanges.org/download/docs/newsletter/2011-2/Landcover_2011-2(89-90).pdf"
}
|
PAGES news • Vol 19 • No 2 • July 2011 the deliverables of the VWG), specifically, an up-to-date metadatabase and inventory of published varved records (Fig. 1). This exercise allowed the group to better identify gaps in reporting methodologies used to establish age-models for varved records, and thus, areas for improvement. Keynote addresses were delivered by experts from the tree ring, ice core, coral and speleothem communities. By learning from other communities tools and methodologies, the goal was to address perceived or actual weaknesses in varve chronologies and dating (Jansen et al., 2007), that may, in part, be responsible for the sparse usage of varved records in climate reconstructions. Each of the keynote addresses was followed by an active group discussion about how “best-practice” techniques in these adjacent fields could be applied and adapted to varved sediment records. Presentations by the participants were organized thematically and interspersed with the four keynote addresses. Several plenary discussion sessions were undertaken on the last day of the workshop to address practical issues, such as how to structure the metadatabase of known varved records, and to provide recommendations for the publication of varved records including the publication of raw data, a full set of images of the enFigure 1: Distribution map of published varved sedimentary records with chronology lengths of at least 100 years. Figure from Ojala et al., in preparation. tire record, and error estimates. Moreover, it was decided to implement a database of papers dealing with varved sediments, and a metadatabase of varved records on the PAGES website. It was also agreed to produce two group publications, one on protocols and a review about the fidelity of sediment varve chronologies. A third workshop of the VWG will be held in the Eifel region of Germany, 21-23 March, 2012, focusing mainly on the calibration of varved records for climate reconstructions.
|
2022-09-14T20:35:06.460Z
|
59,022,578 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1021/JP508636Y",
"MAG": "2141260989",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We carry out first-principles simulations to assess the potential of Pd− Cu−Si metallic glasses as catalysts for oxygen reduction reaction (ORR) using oxygen adsorption energy (EO) as a descriptor. We find that the substitution of Cu on crystalline Pd(111) surface improves the ORR activity while the substitution of Si on the surface is in general detrimental to the ORR activity. Compressive strains are found to weaken oxygen binding on the surface and thus enhance the ORR activity. On the basis of the analysis of EO distribution on the Pd metallic glasses surfaces, we find that for Si-deficient adsorption sites, the local ORR activity could exceed that on pure Pd surface, while Si-rich sites exhibit a rather poor ORR activity. The Pd metallic glasses can sustain a much higher compression than the crystalline counterpart, thus their ORR activity can be improved substantially under a large compression. It is predicted that low-Si Pd metallic glasses could be excellent ORR catalysts under compression.
|
2022-12-12T21:50:13.549Z
|
22,250,621 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1519/JSC.0b013e31821d5c89",
"MAG": "2034024710",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Doder, DV, Babiak, JJ, Janjić, NJ, and Doder, RŽ. Isometric force development of some muscle groups in athletes. J Strength Cond Res 26(1): 293–298, 2012—In a large sample of both male and female athletes, subdivided by age and sex, a development curve of isometric muscule force (&OV0460;) was analyzed for hand flexors, upper-body flexors and extensors, and knee extensors (PDS). A sample of 1,857 male and 1,009 female athletes, aged 8–30 years, subdivided by their age and sex, was used to measure the mean values of isometric muscle force of certain muscle groups by way of 5 topologically defined tests. Based on the results, isometric muscle force (&OV0460;) development curves are shown and analyzed for the right-hand and left-hand (PLS) flexors, upper-body flexors (PTR), upper-body extensors (OTR), and knee extensors (ONO). The application of certain statistical programs gave rise to equations of the relationship between isometric force and age. The maximum mean value of PLS was chosen as the reference value or “the gold standard,” with which PTR, OTR, and ONO were subsequently compared. The relationships were 1:1:1:2.8:5.9 (for male athletes), and 1:1:1.3:3.2:5.2 (for female athletes). The newly derived relationship was recognized as “the canon.” The results may have practical application in athletes' fitness and conditioning. Every topologically defined muscle force has its own patterns and rules that should be closely followed in the training process, because any generalization may lead to false conclusions.
|
2022-12-13T05:36:48.852Z
|
46,021,173 |
{
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"ArXiv": null,
"DOI": "10.1109/ICMC.2014.7231640",
"MAG": "1505395858",
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},
"license": null,
"status": null,
"url": null
}
|
In this paper, a novel control method is proposed for single-input single-output second-order nonlinear systems. The proposed controller guarantees the system reach to the sliding mode surface from any initial states and converge to origin along the surface in finite time while solving the problem of singularity. Compared with traditional fast terminal sliding mode (FTSM) controller, the proposed controller needs less convergence time resulting from a novel sliding mode surface design. A method used in nonsingular terminal sliding mode control is applied in this paper to eliminate the singularity problem. Furthermore, based on the novel sliding mode surface design, a parameter adaptive rule is proposed to make the sliding mode surface close to the initial sates. In this way, the chattering phenomenon is reduced. Finally, simulation results show that the new controller needs less convergence time compared with FTSM, while eliminating the singularity problem and reducing the chattering phenomenon.
|
2022-12-13T09:17:00.420Z
|
25,759,239 |
{
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"DOI": "10.1002/9780470015902.A0003671.PUB2",
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"license": null,
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|
Human behavioural ecology emerged in the mid-1970s as a result of applying the theory of evolution by natural selection to the study of human behaviour. Using explicit models to derive hypotheses that are tested with quantitative data primarily drawn from traditional human communities, it offers a natural science of sociocultural diversity. Recent activity in this field lies in the study of the family, in life history theory and in individual and collective interests, and increasingly the field of enquiry moves from traditional communities to modern industrial societies. Current challenges include incorporating the mechanisms underlying adaptive behaviour, and the developmental and historical causes of human behavioural variability.
Key Concepts:
Human behavioural ecology (HBE) relies on the phenotypic gambit, the claim that how a trait is inherited does not seriously constrain adaptive responses to ecological variation.
HBE derives testable hypotheses from either graphical or mathematically explicit models anchored in basic principles of evolution by natural selection.
An HBE perspective integrates topics that are typically somewhat distinct in conventional anthropology – subsistence, marriage, reciprocity, kinship, demography, politics, ritual and health – into a unified theoretical enquiry.
Initial explorations of HBE were in the field of foraging (hunter-gatherer) subsistence behaviour, drawing explicitly from optimal foraging theory.
An early and enduring focus in HBE is why human communities exhibit such variable culturally sanctioned mating patterns, formalised as marriage rules and marital payments.
Organisms face two major allocation decisions, the first between growth and reproduction, and the second between the number of offspring produced and the amount to be invested in each.
Distinctive features of human life histories, compared to those of other primates and mammals, include: a very large brain, an exceptionally long lifespan, an extended period of juvenile dependence, support of reproduction by older post-reproductive individuals and other kin, and men's support of reproduction through the provisioning of women and their offspring.
The individual selectionist perspective of behavioural ecology highlights the conflict of interests among individuals at each level as well as the potential for cooperation within and between groups, as do some schools within economics, political science and sociology.
The focus of behavioural ecology (both human and other) is principally on adaptive function, whereas evolutionary psychology focuses on mechanism, and cultural evolutionary theory on the transmission of cultural traits.
Behavioural ecologists predict matching between behavioural strategy and context irrespective of whether humans reach this adaptive strategy as a consequence of genes, psychological mechanism or the learning of culture.
Keywords:
adaptation;
evolutionary psychology;
foraging theory;
life history theory;
optimality
|
2022-12-14T05:45:14.846Z
|
218,300,050 |
{
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"ArXiv": null,
"DOI": "10.5445/DIVA/2015-786",
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}
|
08: Vorlesung |
0:00:00 Starten
0:02:00 Motivation and Introduction
0:04:25 MDD Paradigm
0:17:35 Key Concepts and Definitions
0:54:18 Languages and Tools
1:28:30 Research and Practice
|
2022-02-08T01:48:26.789Z
|
229,696,890 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2307/j.ctvwh8f7d",
"MAG": "3007675450",
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},
"license": null,
"status": null,
"url": null
}
|
Walter Benjamin is today regarded as one of the leading thinkers of the twentieth century. Often captured in pensive pose, his image is now that of a serious intellectual. But Benjamin was also a fan of the comedies of Adolphe Menjou, Mickey Mouse, and Charlie Chaplin. As an antidote to repressive civilization, he developed, through these figures, a theory of laughter. Walter Benjamin and the Aesthetics of Film is the first monograph to thoroughly analyse Benjamin’s film writings, contextualizing them within his oeuvre whilst also paying attention to the various films, actors, and directors that sparked his interest. The book situates all these writings within Benjamin’s ‘anthropological materialism’, a concept that analyses the transformations of the human sensorium through technology. Through the term ‘innervation’, Benjamin thought of film spectatorship as an empowering reception that, through a rush of energy, would form a collective body within the audience, interpenetrating a liberated technology into the distracted spectators. Benjamin’s writings on Soviet film and German cinema, Charlie Chaplin, and Mickey Mouse are analysed in relation to this posthuman constellation that Benjamin had started to dream of in the early twenties, long before he began to theorize about films.
|
2022-07-09T06:38:58.633Z
|
40,499,459 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CITCON.2004.1309850",
"MAG": "1705736165",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Ciment Quebec Inc. is located in St. Basile, Quebec, Canada. The company have embarked on a project to upgrade their existing mill. Ciment Quebec has completed phase one of the project with an increase in capacity from the previous 185 mtph to over 200 mtph.
|
2022-08-26T13:45:51.300Z
|
192,250,339 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/14682737.2018.1419000",
"MAG": "2791454015",
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},
"license": null,
"status": null,
"url": null
}
|
Abstract This article analyses the subversive depiction of Mexican ‘national spaces’, such as homes, churches, and cemeteries, in Luis Buñuel’s El ángel exterminador (1962) and Juan Rulfo’s Pedro Páramo (1955). Although both of these artists have been studied in considerable depth, a detailed comparison of their works remains to be carried out, particularly with respect to their innovative approach to spatiality. Both Buñuel’s film and Rulfo’s novel feature key physical and conceptual spaces which enclose and imprison their characters and I seek to link this sense of entrapment to a critique of nationalist cultural hegemony. The analysis will be carried out by applying Foucault’s (1986) concept of the heterotopia along with Lefebvre’s (1991) idea of ‘national space’. This new research will contribute towards a deeper understanding of spatiality in mid-twentieth century Mexican Modernism and a greater awareness of the myriad links between these two experimental artists.
|
2022-09-05T10:28:38.941Z
|
17,800,878 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CDC.2003.1272851",
"MAG": "1480781224",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In practice, one is not only interested in the qualitative characterizations provided by Lyapunov stability, but also in quantitative information concerning system behavior, including estimates of trajectory bounds, possibly over finite time intervals. This type of information has been ascertained in the past in a systematic manner, using the concept of practical stability. In the present paper, we give a new definition of generalized practical stability (abbreviated as GP-stability) and establish some sufficient conditions concerning GP-stability for a wide class of discontinuous dynamical systems. As in the classical Lyapunov theory, our results constitute a direct method, making use of auxiliary scalar-valued Lyapunov-like functions. These functions, however, have properties that differ significantly from the usual Lyapunov functions. We demonstrate the applicability of our results by means of several specific examples.
|
2022-09-13T13:21:41.354Z
|
22,368,187 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/path.2182",
"MAG": "2014608793",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Neuropilin‐1 (Np1) and neuropilin‐2 (Np2) are transmembrane glycoproteins with large extracellular domains that interact with both class 3 semaphorins and vascular endothelial growth factor (VEGF), and are involved in the regulation of many physiological pathways, including angiogenesis. The neuropilins also interact directly with the classical receptors for VEGF, VEGF‐R1 and ‐R2, mediating signal transduction. The heart, glomeruli and osteoblasts express both Np1 and Np2, but there is differential expression in the adult vasculature, with Np1 expressed mainly by arterial endothelium, whereas Np2 is only expressed by venous and lymphatic endothelium. Both neuropilins are commonly over‐expressed in regions of physiological (wound‐healing) and pathological (tumour) angiogenesis, but the signal transduction pathways, neuropilin‐mediated gene expression and the definitive role of neuropilins in angiogenic processes are not fully characterized. This review details the current evidence for the role of neuropilins in angiogenesis, and suggests future research directions that may enhance our understanding of the mechanisms of action of this unique family of proteins. Copyright © 2007 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
|
2022-12-28T18:16:28.552Z
|
97,777,409 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5006/1777",
"MAG": "2181197702",
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},
"license": null,
"status": null,
"url": null
}
|
For more than four decades, tannins extracted from renewable resources have been used to protect steam boilers at levels significantly above ASME guidelines. Using tannin-based (green) corrosion in...
|
2022-12-28T18:16:52.836Z
|
83,892,647 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1526-100X.2012.00872.x",
"MAG": "1980319577",
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},
"license": null,
"status": null,
"url": null
}
|
Large‐scale (circa 500 ha) restoration of species‐rich dry grasslands was conducted using a high‐diversity regional seed mixture in the White Carpathians Protected Landscape Area and Biosphere Reserve, Czech Republic, Central Europe. After sowing, the restored grasslands were regularly mown. Vegetation was analyzed at sites restored 1–12 years ago and compared with that of ancient, extremely species‐rich grasslands nearby. Nearly all (98%) sown target species successfully established and nearly half of unsown target species established spontaneously, partly dependent on distance to the ancient grasslands. Early mowing in the first half of June appeared to support species diversity and broad‐leaved forbs at the expense of competitive grasses. Using a regional seed mixture appeared to be an effective way of restoring dry grasslands and is especially recommended in the proximity of still existing ancient grasslands where spontaneous establishment of unsown target species may reinforce the success of restoration more easily.
|
2023-01-01T18:39:47.137Z
|
231,512,117 |
{
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"ArXiv": null,
"DOI": "10.19083/tesis/624302",
"MAG": "3092749538",
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},
"license": "CCBYNCSA",
"status": "HYBRID",
"url": "https://repositorioacademico.upc.edu.pe/bitstream/10757/624302/10/ZEGARRA_PC.pdf"
}
|
This professional project develops an Enterprise Architecture proposal for a consulting firm that offers the implementation service of the Law on Protection of Personal Data, emphasizing the process of Data Bank Registration.
The content is divided into four chapters. The first allows knowing the company, its strategy and objectives and benefits of the project. The second chapter details the theoretical foundations on Enterprise Architecture and agile methods for software development. The third chapter develops the Enterprise Architecture, which, based on the current and desired situation, allows a gap analysis and presents an implementation plan that proposes the development of a system that automates the service. This proposal begins with the analysis of the strengths and weaknesses of the organization and its software development team, continues with the definition of the Scrum framework and the dynamics and tools to be used, and ends defining the total cost of the solution. Finally, the fourth chapter summarizes the previous ones to propose a project that defines the problem, how it will be solved, describes the team that will materialize the solution and considers its technical and financial feasibility.
The main problem is that consulting firms, to increase their income, they need to hire new skilled workers to bill more hours to customers. This paper concludes that it is possible to use technology to create "products into services" to achieve a non-linear growth in sales.
|
2022-01-27T02:20:23.011Z
|
230,601,802 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.30972/fhn.0394609",
"MAG": "3110981668",
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},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://revistas.unne.edu.ar/index.php/fhn/article/download/4609/4300"
}
|
En el presente trabajo nos avocamos al análisis de la actividad exportadora de los puertos de Entre Ríos entre 1958 (sin conectividad material con el continente) y 1983 (con conectividad casi plena tanto con la Argentina como con la República Oriental del Uruguay). El objetivo es determinar el impacto de las conexiones materiales (túnel y puentes) en la dinámica portuaria entrerriana. Comenzaremos con un análisis general de la participación de los puertos entrerrianos en la recaudación aduanera del período y los productos que fueron objeto de exportación para luego realizar un análisis más detallado de los procesos que fueron vividos en los trece puertos (cinco sobre el Río Uruguay y ocho sobre el Río Paraná) con actividad portuaria durante el período. La principal fuente utilizada son los Anuarios Estadísticos o Anuarios de Comercio Exterior de la Argentina publicados entre esos años.
|
2022-01-27T20:28:21.090Z
|
19,990,172 |
{
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"DOI": "10.1109/IWMPI.2013.6528362",
"MAG": "1989711828",
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},
"license": null,
"status": null,
"url": null
}
|
Optimized methods in MRI allow for qualitative and quantitative in-vivo cell-tracking and monitoring of organ distribution of SPIO-labeled MSC in clinical acute renal failure (ARF) in rate at a clinical 3T MR system. The study demonstrates the potential of in-vivo MRI for qualitative tracking and quantification of SPIO-labeled stem cells in future therapeutic treatment protocols.
|
2022-02-12T22:31:24.912Z
|
237,549,365 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/envhis/emy165",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
After Benito Mussolini and fascist Italy conquered the Abyssinian (Ethiopian) Empire and created Italian East Africa in 1936, the new imperial rulers set about constructing a massive network of roads to tame the terrain and control the colonial landscape. As Andrew Denning explains in this issue’s Gallery essay, fascist officials quickly turned to visual images to propagandize their infrastructural achievements to Italian audiences. Denning looks closely at a wide range of visual sources, including photographs, paintings, and maps, to examine the ideology of roadbuilding promoted by these pictures. He explains how Mussolini and others associated the road projects with ancient Rome and drew on classical iconography to celebrate modern empire. He considers the power dynamics of race and labor in road construction, carefully noting what the images reveal and what they obscure. His essay provides new insight into the environmental history of Italian East Africa, while also raising broader questions about the visual history of empire.
|
2022-07-01T03:44:43.922Z
|
246,070,935 |
{
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"ArXiv": null,
"DOI": "10.1093/oso/9780192897107.003.0004",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
Chapter 4 discusses challenges in rural labour markets in LICs, a fundamental issue given that small-scale farming remains the primary source of income for a majority of the population in low-income countries. GLM|LIC projects spanning a number of African countries show that labour markets in rural areas often do not work efficiently, leaving many distortions in the supply of labour and in productivity. The chapter discusses topics related to credit constraints, the seasonality cycles of lean and harvest season, and the challenge of smoothing consumption over time. It also addresses the important question of whether Public Works Programmes (PWPs) are effective. PWPs are very important in many LICs, receiving large amounts of money from governments and international agencies. These programmes are designed with a number of goals in mind, including employment creation, poverty reduction, and infrastructure development.
|
2022-08-20T18:39:18.175Z
|
43,846,941 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/IRANIANCEE.2014.6999724",
"MAG": "1994419742",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Overheat of the Lithium-ion battery during the charge process lead to decrease in capacity of the battery, cycle life, and charge efficiency. Safe and reliable charging methods require control of the battery temperature. In this paper, a min-max charging strategy based on a nonlinear equivalent circuit-Thermal model a Lithium-ion battery is proposed. The min-max optimal problem of specifying the optimal charging current is defined and the constraints such as current, temperature, and voltage limits are intended. The object of min-max optimal control is minimizing maximum irreversible heat that is generated by electrical current flow through the battery. Charging current is calculated by solving min-max optimal control problem. The employment of such current in charging system is difficult according to its fast variations. To solve this problem, the calculated current injected into the battery has been limited to some specified levels. The proposed charging strategy is compared with constant current-constant voltage method and simulated in MATLAB software to verify its validity. The minmax strategy is capable of reducing the heat generation and time of charging by 37.5% and 43 % respectively.
|
2022-09-12T05:00:38.411Z
|
14,742,682 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1364/OL.20.001292",
"MAG": "2053636924",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We report, for the first time to our knowledge, generation of a tunable miltiterahertz modulation signal on an optical carrier directly from a single laser source. The modulation frequency, which can be tuned from 0.15 THz to more than 7 THz, is the beat note obtained by varying the spectral separation between the coaxial two-color output of a two-wavelength laser-diode array from 0.32 to 17 nm. The frequency characteristics of the terahertz beat note are determined with a noncollinear intensity autocorrelator.
|
2022-12-17T08:51:50.165Z
|
240,158,933 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CRC52766.2021.9620150",
"MAG": null,
"PubMedCentral": null
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"license": null,
"status": null,
"url": null
}
|
In many emerging Time Sensitive Networking (TSN) applications such as industrial control and automotive, periodic traffic with end-to-end latency constraints is buffered with nonmission-critical aperiodic traffic. As queueing delay is a central component of end-to-end latency, we study the effect of aperiodic traffic on the queueing delay of periodic traffic via characterizing the probability distribution of queue size and delay in an (M + D)/M/1 queue, a queue with Poisson and periodic inputs, infinite waiting capacity and a single memoryless server. Since obtaining the closed form distributions of the queue size and delay is intractable, we approximate the behavior of the (M + D)/M/1 queue when the service and arrival rates are close. We use a Markov chain with a quasitoeplitz matrix, enabling us to use an existing technique to study this class of Markov chains. We determine the transition matrix of the Markov chain, investigate the setting in which the approximation works well, and compute the stationary distribution. We plot and compare the stationary distributions of queue size and delay between the (M + D)/M/1 queue and our model; we observe that our model is a favorable match.
|
2022-01-27T01:39:08.786Z
|
225,675,754 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.20491/isarder.2020.951",
"MAG": "3037938563",
"PubMedCentral": null
},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://doi.org/10.20491/isarder.2020.951"
}
|
Makale Kategorisi: Araştırma Makalesi Amaç – Vinç sahibi işletmeler, yedek parça ihtiyaçları için verilen tedarik hizmeti tekliflerini farklı yöntemlerle değerlendirirler. Değerlendirme ve karar verme aşamasında önem verdikleri konular da farklı olabilir. Bu durum, müşteri kriter önceliklerini belirlemede sorun yaşayan yedek parça tedarikçilerinin müşteri / gelir kaybetmesine sebebiyet vermektedir. Bu çalışmanın amacı, vinç sahibi işletmelerin yedek parça tedarik hizmeti alırken öncelik verdikleri kriterlerini belirleyip, bu bulgular doğrultusunda tedarikçi firmaya, uygulayabileceği en uygun satış stratejileri konusunda öneriler sunulmasıdır.
|
2022-01-23T04:20:28.886Z
|
218,532,320 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2152/jmi.67.174",
"MAG": "3022844986",
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://www.jstage.jst.go.jp/article/jmi/67/1.2/67_174/_pdf"
}
|
Background : High blood pressure (BP) is a healthcare problem in young persons. There are racial differences in anthropometrics, dietary habit and lifestyle relating to BP. Therefore, this study investigated the relationship between anthropometrics, lifestyle and BP obtained in the Japanese university students. Materials and Methods : Participants were recruited in annual health screening including questionnaire, measurements of BP and anthropometrics calculating body mass index (BMI). Totally, 14,280 students (10,273 males and 4,007 females) were eligible. Multiple regression analyses were applied to predict contributors to high BP. Results : BMI was the most powerful contributor to high BP in many subgroups divided by gender and graduation (p < 0.001). In lifestyle, contribution of lack of exercise to high BPs was observed in the undergraduates. Smoking, drinking and breakfast skipping had no significant impact on high BP. However, smoking and drinking permeated and exercise habit declined after graduation. Prevalence of obesity (BMI ≥ 25 kg / m2) and hypertension ( ≥ 140 / 90 mmHg) increased in subgroups with advanced age (p < 0.001). Conclusion: BMI was found to be the most powerful contributor to high BPs. Health literacy to modify lifestyle is important to prevent hypertension for university students who are exposed to social trends of unhealthy lifestyle. J. Med. Invest. 67 : 174-181, February, 2020.
|
2022-09-18T16:07:52.484Z
|
225,278,839 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2118/203826-pa",
"MAG": "3089995550",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Hydrocarbon fields that are located offshore Abu Dhabi, United Arab Emirates (UAE), are known to be associated with undulating thick sedimentary sequences. These undulations are mostly influenced by variations in the depth of Infracambrian Hormuz salts that generate negative gravity anomalies. Nonetheless, a few known oil fields are uncorrelated with the airborne gravity observations. This is attributed to the interference from large positive gravity anomalies from basement highs. To filter out the effect of basement, we calculate the pseudogravity effect of the airborne magnetic anomalies and subtract it from the gravity anomalies. The resultant gravity anomalies mainly represent the effect of the salt domes. The results uncover deep salt structures and introduce potential traps for hydrocarbons that have proved difficult to map accurately with current seismic techniques. A nonlinear 3D inversion modeling of corrected magnetic and decreased gravity data is also used to determine the depth to basement and the Infracambrian Hormuz salts over two regions. Our findings demonstrate that the depth to basement in these regions changes from 7100 to 9700 m, and the depth to Infracambrian Hormuz salt changes from 5800 to 9400 m, with a variable thickness with a maximum of 2700 m.
|
2022-11-07T17:34:31.426Z
|
21,219,693 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/IMCTL.2015.7359573",
"MAG": "2206549876",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper presents a new educational platform for young children. It is based mainly on serious games and semantic web. The platform is used to assess and monitor the children' progress and performance in meeting preset learning objectives without any manual intervention. The learning games are used to improve the children's learning outcomes and keep them motivated. The platform monitoring features allow the teachers to focus on the children' achievement of every learning objective and empower also the parents' engagement in their children's learning experience. In fact, they can follow up the children and know their weaknesses and strengths. A new ontology is proposed to map the programs curriculums and learning objectives with the flow-driven game worlds' elements. The children' performance is evaluated through the ontology using information extraction with an automated reasoning mechanism that is guided by a set of inference rules. The platform is implemented in a 3-tier architecture where mobile game applications are used. These games can query and update the ontology in real time through a web service by invoking data management, reasoning, monitoring and reporting operations using Apache Jena Ontology API. The platform can be used to dynamically generate the content of the games based on the children' preferences and acquired knowledge.
|
2022-12-12T08:19:48.188Z
|
244,528,989 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.48095/ccachp2021113",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
BACKGROUND
Fingertips are the most commonly injured anatomical structures in the upper extremity. The aim of this work is to present our experience in the management of fingertip injuries.
METHODS
All patients with fingertip injuries managed by Plastic and Reconstructive Surgery Division of Hospital General “Dr Manuel Gea Gonzalez” in Mexico from July 2010 to June 2015 were included; their demographic characteristics were described, as well as patterns of injury and management.
RESULTS
A total of 1,265 patients were included in the study, 75% were males. The mean age of presentation was 20.5 ± 16.46 years; the age group most commonly affected was younger than 15 years (46.7%). Right and left-sided injuries were almost equally prevalent (51 vs. 49%). The most commonly injured fingers were the third (27.2%), and second (25.8%). Eighty-seven percent of the patients presented with single-digit injuries. Fingertip amputations were the most common type of injury with 620 cases (49%), followed by simple fingertip lacerations (574 cases, 45%), and nail bed injuries in 71 cases (5.6%). Surgical management was necessary in 95.8% of the cases.
CONCLUSIONS
Fingertip injuries remain the most common reason for consultation in hand emergencies. A structured approach for their treatment is necessary to obtain the best clinical outcomes.
|
2022-12-15T23:21:14.698Z
|
110,484,964 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1109/ULTSYM.1983.198005",
"MAG": "2112968376",
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},
"license": null,
"status": null,
"url": null
}
|
A general procedure for perturbing SAW filter designs is described The procedure has both experimental and data manipulation components Software techniques suitable for extracting Rayleigh wave data from the several sources of signal transport present in SAW filters are presented Residual spurious data levels are shown to be 50 dB below the peak of the Rayleigh portion of the impulse response A twolevel metal fabrication procedure for altering packaged devices in situ is described This technique permits a quantitative assessment of the relation between perturbations to the IDT geometry and the consequent perturbations to the Rayleigh impulse response
|
2022-01-27T15:53:47.281Z
|
165,482,394 |
{
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"ArXiv": null,
"DOI": "10.14296/518.9780992725716",
"MAG": "2804185124",
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},
"license": "CCBYNCND",
"status": "HYBRID",
"url": "https://doi.org/10.14296/518.9780992725716"
}
|
The Hilda Hulme Memorial Lectures were established in 1985 following a donation from Mr Mohamed Aslam in memory of his wife, Dr Hilda Hulme. The lectures are on the subject of English literature and relate to one of ‘the three fields in which Dr Hulme specialised, namely Shakespeare, language in Elizabethan drama, and the nineteenth-century novel’.
|
2022-02-08T19:56:33.083Z
|
133,955,056 |
{
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"ArXiv": null,
"DOI": "10.5710/PEAPA.04.06.2018.259",
"MAG": "2894939306",
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},
"license": null,
"status": null,
"url": null
}
|
Resumen. La palinologia de sitios arqueologicos o arqueopalinologia ha sido frecuentemente utilizada en la Argentina tanto para reconstruir la vegetacion y los ambientes desde el final del Pleistoceno Tardio hasta tiempos recientes, como para inferir ciertas actividades culturales desarrolladas dentro de los sitios arqueologicos. En el presente trabajo se realizo una revision de los analisis polinicos realizados a partir de depositos sedimentarios en sitios arqueologicos en cuevas, aleros y en contextos abiertos correspondientes a sociedades de cazadores-recolectores de la Argentina (32o–52o S), independientemente del periodo cronologico o cultural. Se explican las metodologias aplicadas y los resultados obtenidos y se discuten (1) las limitaciones del analisis polinico; (2) las diferentes formas en que los datos de polen son utiles en este tipo de sitios arqueologicos, y (3) los procesos tafonomicos tales como dispersion, depositacion y preservacion polinica en estos ambientes depositacionales. La potencialidad y aplicacion del analisis polinico en arqueologia de sitios cazadores-recolectores se ejemplifico con trabajos representativos en la region pampeana y patagonica, donde se han realizado la mayoria de los estudios arqueopalinologicos. Estos estudios, aunque complejos, ofrecen oportunidades unicas para comprender los entornos y las actividades humanas del pasado. Palabras clave. Palinologia. Arqueologia. Tafonomia polinica. Abstract. ARCHEOPALYNOLOGY: A REVIEW OF POLLEN ANALYSIS IN CAVES, SHELTERS AND OPEN CONTEXTS OCCUPIED BY HUNTERGATHERER SOCIETIES OF ARGENTINA (32o–52o S). Archeopalynology has been frequently used in Argentina to reconstruct vegetation and environments since the end of Late Pleistocene to the present, and to infer different cultural activities developed into the archaeological sites. The present paper presents a review of pollen analysis of sedimentary sequences from archaeological sites located in caves, shelters and open contexts occupied by hunter-gatherer societies of Argentina (32o–52o S), regardless the chronological or cultural period. The methodologies applied and results obtained are explained and the following topics are discussed (1) the limitations of the pollen analysis; (2) the different ways in which pollen data are useful in this type of archaeological sites; and (3) the taphonomic processes such as pollen dispersal, deposition and preservation in these depositational environments. The potentiality and application of pollen analysis in archaeology of hunter-gatherer sites were exemplified by representative works in the Pampa and Patagonia regions, where most of the archeopalynology studies have been carried out. These studies, often complex, offer unique opportunities to understand the environments and human activities of the past. Key words. Palynology. Archaeology. Pollen taphonomy.
|
2022-02-09T12:23:15.041Z
|
242,436,348 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1755-1315/560/1/011001",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://doi.org/10.1088/1755-1315/560/1/011001"
}
|
The 2020 4th International Conference on Water Conservancy, Hydropower and Building Engineering (WCHBE 2020) was planned to be held in Lanzhou, China during July 3-5, 2020. WCHBE 2020 was hosted by AEIC Academic Exchange Information Center. Due to the impact of COVID-19, many communities from all over the world were under strict health measures and strict travel restrictions, and participants of 2020 4th International Conference on Water Conservancy, Hydropower and Building Engineering (WCHBE 2020) also meet with the difficulty of travel restrictions. For communities, if our conference was not held in a virtual form, it would add huge work on traffic system, Exit-Entry system, medical system, etc., which is quite a serious issue, to actively respond to the call of the government, to strengthen the protection work, to effectively reduce people gathering and prevent COVID-19, considering the situation that most of the authors would like to publish their articles and make academic communications as scheduled, WCHBE 2020 was held on-line instead of postponing the conference. It was a challenge, not only to the organizers, but also to the participants who were delivering their speeches using videoconference tools, under different time zones. The conference is an international conference for the presentation of technological advances and research results in the fields of water conservancy, hydropower and building engineering. The conference will bring together about 97 leading researchers, engineers and scientists in the domain of interest from China, Italy, Malaysia, Mexico and Thailand. The conference model was divided into two parts, including keynote presentations and online discussion. In the first part, each keynote speakers were allocated 30 minutes to present their talks via Zoom. After the keynote talks, all participants joined in a WeChat communication group to discuss more about the talks and presentations. We are honored to have invited three distinguished experts as our keynote speakers. Prof. Hengjia Zhang, Gansu Agricultural University, China, was the first one to perform a thought-provoking speech on Optimization of Limited Irrigation Schedules for Spring Maize (Zea mays) in a Desert Oasis Region. He also was the Conference Chair who mainly devoted to the teaching and research work of the efficient use of agricultural water and soil resources. Secondly, Prof. Shaohua Marko Hsu from Feng Chia University held his speech on Using Porous Material for Riverbank and Riverbed Protection. Thirdly, Prof. Ahmad Safuan Bin A. Rashid from Universiti Teknologi Malaysia, Malaysia talked about Application of UAV-TLS Photogrammetry in Determination of Rock Slope Stability. Their insightful speeches had triggered heated discussion in the second session of the conference. The WeChat discussion lasted for about 30 minutes. Every participant praised this conference for disseminating useful and insightful knowledge. We are glad to share with you that we still received lots of submissions from the conference during this special period. Hence, we selected a bunch of high-quality papers and compiled them into the proceedings after rigorously reviewed them. These papers feature following two categories but are not limited to: Civil, Architectural Engineering, Water conservancy and hydropower, and other related fields. All the papers have been through rigorous review and process to meet the requirements of International publication standard. We would like to express our gratitude to everyone involved. Without this dedicated cooperation, it would be impossible to hold the conference at such a high level and prepare the WCHBE 2020 proceedings. Committee of WCHBE 2020 The Committee member is available in this pdf.
|
2022-07-21T02:54:04.145Z
|
73,070,824 |
{
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"ArXiv": null,
"DOI": "10.1093/ndt/14.9.2071",
"MAG": "2124743294",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://academic.oup.com/ndt/article-pdf/14/9/2071/23769993/142071.pdf"
}
|
The ERA–EDTA Council has elected us to take over, easy and broad access to the journal on the World Wide Web. In the near future, we aim to handle the as of July 1 1999, the scientific direction of Nephrology Dialysis Transplantation. We are fully aware of the article submission process through Internet. This in turn should allow us to accelerate the publication great honour, but also of the responsibility and workload that this task represents. It will of course be process. As in the past, we will be relying on the continuing good will and efforts of our highly dedicated difficult to match the outstanding performance of our immediate predecessors, Professor Eberhard Ritz from reviewers from all over the world, and on the unfailing commitment of our Subject Editors and Editorial Heidelberg, Germany, and Professor Hein Koomans from Utrecht, Holland. Fortunately, it will not be Board. We know that peer reviewing is a difficult and time-consuming task, especially when the referee is necessary to repeat the admirable pioneering work done by the first Editor-in-Chief of the journal, asked to make decisions on areas of research which are not always his/her own field. Clearly, the peer Professor Alex M. Davison of Leeds, UK. Due to relentless efforts of our predecessors, NDT evaluation of original articles by clinical and basic research scientists is, and must remain, the cornerstone has become a well-known and highly esteemed journal of our speciality. It occupies a firm place among the of medical science journals like NDT, in contrast with the increasing amount of unreviewed scientific informamajor journals of nephrology, with a subscription number exceeding 5000 copies per month. Its particular tion of all kinds. It gives us great satisfaction to work with motivated colleagues, whose assistance, alertness, focus is on clinical matters, including clinical and clinically oriented experimental research and continuand critical abilities are vital in the achievement of our common goal: to further the scientific value of original ing medical education. It has also become a platform for nephrological news worldwide. We are particularly work published in NDT. We know that it will be no easy task to run the pleased about the growing exposure of our journal to a readership and authorship from all continents. journal, given the pressures of increasingly unlimited information from other sources. Nonetheless we are Our aim is to maintain these general policies which have been successful from the outset, and which have confident that there is a niche for our journal, as recently pointed out by Eberhard Ritz. It should be progressively increased the journal’s reputation. We intend not only to maintain established achievements, maintained and if possible extended, with the constant help of our contributors and readers. but to introduce new openings. Given the indisputable advantages of electronic transmission, we have begun to work, in collaboration Tilman Drüeke Norbert Lameire Editor-in-Chief Deputy Editor with our publishers, Oxford University Press, on an
|
2022-08-03T20:12:20.129Z
|
133,858,196 |
{
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"ArXiv": null,
"DOI": "10.4337/9781785363849.00034",
"MAG": "2909057654",
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},
"license": null,
"status": null,
"url": null
}
|
Climate change is an increasingly urgent matter of global politics, a consequence of the huge success of the fossil-fueled global economy. The longstanding discussion of the Gaia hypothesis, James Lovelock’s ideas of earth as a self-regulating life system, and the dangers that rising greenhouse gas concentrations present to this system, foreshadow contemporary earth system science discussions. The formulation of earth as now in a new geological epoch, the Anthropocene, has added forcefully to Lovelock’s contentions, and made it clear that globalization now needs to be understood as a driving force operating at such a scale that it is transforming the planet in ways that are very dangerous for the future of humanity. Current attempts to tackle climate change are only the beginning of what needs to be done to shape the Anthropocene in ways that will be benign to humanity’s future.
|
2022-09-02T04:19:43.101Z
|
145,228,297 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1177/0305735607070375",
"MAG": "2104771324",
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},
"license": null,
"status": null,
"url": null
}
|
The present study focused on mood effects of high-tempo (HT) or low-tempo (LT) music on a high-or a low-arousal stressful task condition (HST or LST), manipulating the relationship between affective valence and psycho-physiological arousal. In Experiment 1, 20 participants listened to the HT or LT music immediately after the HST or LST condition, determining heart rate (HR), skin conductance level (SCL), respiratory rate (RR), cortisol (CS) concentration level, and visual analogue scales (VAS). Experiment 2 established a 10-minute rest between stressful and musical conditions by using a method similar to that used in Experiment 1. Consequently, in Experiment 1, the LT music significantly reduced HR levels under the HST condition. In addition, in subjective vector analyses derived from the VAS, the LT music indicated stress-distractive effects on the HST condition (arousal allopathy) and on the LST condition (arousal sympathy). In Experiment 2, there were arousal-moderating effects of the LT music in all stress groups.
|
2022-10-01T14:51:03.450Z
|
251,273,487 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.3390/jfb13030106",
"MAG": null,
"PubMedCentral": "9397017"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2079-4983/13/3/106/pdf?version=1659079751"
}
|
Dental pulp is essential for the development and long-term preservation of teeth. Dental trauma and caries often lead to pulp inflammation. Vital pulp therapy using dental pulp-capping materials is an approach to preserving the vitality of injured dental pulp. Most pulp-capping materials used in clinics have good biocompatibility to promote mineralization, but their anti-inflammatory effect is weak. Therefore, the failure rate will increase when dental pulp inflammation is severe. The present study developed an amorphous calcium phosphate/poly (L-lactic acid)-poly (lactic-co-glycolic acid) membrane compounded with aspirin (hereafter known as ASP/PLGA-ASP/ACP/PLLA-PLGA). The composite membrane, used as a pulp-capping material, effectively achieved the rapid release of high concentrations of the anti-inflammatory drug aspirin during the early stages as well as the long-term release of low concentrations of aspirin and calcium/phosphorus ions during the later stages, which could repair inflamed dental pulp and promote mineralization. Meanwhile, the composite membrane promoted the proliferation of inflamed dental pulp stem cells, downregulated the expression of inflammatory markers, upregulated the expression of mineralization-related markers, and induced the formation of stronger reparative dentin in the rat pulpitis model. These findings indicate that this material may be suitable for use as a pulp-capping material in clinical applications.
|
2022-10-28T08:59:07.613Z
|
11,408,640 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/PLANKT/FBT100",
"MAG": "2166904041",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Dormancy (diapause) is a key life-history strategy of pelagic copepods that allows them to thrive in highly seasonal environments. Successful dormancy of copepodid stages requires the ability to store energy efficiently (for example as lipids) and to slow down the rate of mobilization of this capital during the dormant period. The physiology of lipids in copepods has been extensively reviewed; however, data about the energetics of dormancy are currently scattered throughout the literature. Thus, we conducted a meta-analysis comparing the metabolism of active and dormant copepods in 15 species that undergo dormancy as copepodids. Linear mixed-effects models showed that the metabolic rate of dormant copepods is about one-fourth of the values for actively growing copepods, a level that remains consistent across a large range of body size or environmental conditions. Based on these metabolic rates, we used a numerical modelling approach to predict dormancy duration as a function of body mass and ambient temperature, and to explain the observed range of body masses at the initiation of dormancy. Our numerical approach also provides explanations for interand intra-specific variability in life-history strategies, such as
|
2022-11-25T16:36:28.992Z
|
23,249,850 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/00002060-200107000-00006",
"MAG": "2020330329",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Pages I-H, Jahr S, Schaufele MK, Conradi E: Comparative analysis of biofeedback and physical therapy for treatment of urinary stress incontinence in women. Am J Phys Med Rehabil 2001;80:494–502. ObjectiveTo compare the effectiveness of an intensive group physical therapy program with individual biofeedback training for female patients with urinary stress incontinence. DesignRandomized study of two therapeutic interventions consisting of a specific physical therapy program (PT) or biofeedback training (BF) daily for 4 wk, followed by a 2-mo, unsupervised home exercise program in both groups in an outpatient clinic of a large university hospital. Forty women, referred by gynecologists for nonoperative treatment of genuine stress incontinence of mild-to-moderate severity, were included. Measurements of daytime/nocturnal urinary frequency and subjective improvement of incontinence were the main outcome measures at initial presentation, after completion of the therapy program, and at follow-up after 3 mo. Standardized examinations of digital contraction strength, speculum tests, and manometric measurements were documented as secondary outcome measures. ResultsIn the PT group, the daytime urination frequency decreased 22% after 4 wk of therapy and 19% after 3 mo (P < 0.05) from baseline. The nocturnal urination frequency was reduced by 66% after 4 wk of therapy and 62% after 3 mo (P < 0.001). In the BF group, the daily urination frequency decreased 10% after 4 wk of therapy and 5% after 3 mo (P > 0.05). The nocturnal urination frequency declined 36% after 4 wk of therapy and 66% after 3 months (P < 0.05). Subjective assessment after 3 mo showed that in the PT group, 28% of patients were free of incontinence episodes, 68% reported improved symptoms (incontinence episodes improved by >50%), and 4% were unchanged. In the BF group, 62% were free of incontinence episodes, and 38% were improved. Results of the digital contraction strength assessments, speculum tests, and manometric measurements showed statistically significant improvement in all variables in both groups after 3 months. ConclusionFour weeks of both intensive group physical therapy or individual biofeedback training followed by an unsupervised home exercise program for 2 mo are effective therapies for female urinary stress incontinence and result in a significantly reduced nocturnal urinary frequency and improved subjective outcome. Only group physical therapy resulted in reduced daytime urinary frequency. BF therapy resulted in a better subjective outcome and higher contraction pressures of the pelvic floor muscles.
|
2022-12-09T23:55:05.007Z
|
254,394,931 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1115/1.4017532",
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"license": null,
"status": null,
"url": null
}
|
This paper demonstrates the practicability of determining the proper shape of a cam to produce a required motion by means of what might be termed “geometrical kinematics.” The author shows how the general principles of geometry and kinematics can be applied and that the graphical method is not limited to determining a cam profile as the envelope of the follower. The methods of kinematics, including graphical construction, can determine points of contact and centers of curvature, so as to avoid cusps. Dimensions of the cam can be obtained to any desired degree of accuracy by calculations based upon the geometrical constructions. Designers and draftsmen will find the methods explained easy to understand and use.
|
2022-12-08T16:58:51.415Z
|
157,605,737 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.15408/sjie.v6i1.4302",
"MAG": "2594124684",
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "http://journal.uinjkt.ac.id/index.php/signifikan/article/download/4302/3318"
}
|
This study empirically explores the factors motivating Muzakki (zakat payers) to pay zakat at the Baitul Mal Aceh, Indonesia. The factors motivating Muzakki to pay zakat investigated in the study comprises culture, regulation, motivation, and Muzakki understanding on zakat. 600 questionnaires were disseminated to the respondents, which were selected based on the convenience sampling technique. Then, the data were analysed using a binary logistic regression. The results of this study showed that culture, regulation, motivation, and understanding of the Muzakki on zakat significantly and positively affected the decision of Muzakki to pay their zakat at the Baitul Mal Aceh. This study implies that in order Muzakki to pay their zakat at the Baitul Mal, Islamic cultures should be preserved among Achenese, government should enhance regulation pertaining zakat management and the people of Aceh need to be equipped with the relevant knowledge on the obligation of zakat payment. DOI: 10.15408/sjie.v6i1.4302
|
2022-12-13T15:00:21.914Z
|
19,154,777 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/exsy.12242",
"MAG": "2792457660",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A physical activity recommendation system promotes active lifestyles for users. Real‐world reasoning and recommendation systems face the issues of data and knowledge integration, knowledge acquisition, and accurate recommendation generation. The knowledge‐based reasoning and recommendation framework (KRF) proposed here, which accurately generates reliable recommendations and educational facts for users, could solve those issues. The KRF methodology focuses on integrating data with knowledge, rule‐based reasoning, and conflict resolution. The integration issue is resolved using a semi‐automatic mapping approach in which rule conditions are mapped to data schema. The rule‐based reasoning methodology uses explicit rules with a maximum‐specificity conflict resolution strategy to ensure the generation of appropriate and correct recommendations. The data used during the reasoning process are generated in real time from users' physical activities and personal profiles in order to personalize recommendations. The proposed KRF is part of a wellness and health care platform, Mining Minds, and has been tested in the Mining Minds integrated environment using a sedentary user behaviour scenario. To evaluate the KRF methodology, a stand‐alone, open‐source application (Version 1.0) was released and tested using a dataset of 10 volunteers with 40 different types of sedentary behaviours. The KRF performance was measured using average execution time and recommendation accuracy.
|
2022-12-10T08:24:43.334Z
|
243,332,898 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1108/oxan-db260359",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Significance
The growth of Russian-Chinese security and defence cooperation over recent years has led to talk of a formal military alliance, which President Vladimir Putin said in 2020 was "conceivable" but not a current goal.
Impacts
Chinese participation in Russia’s Zapad-21 wargames this year would signal support (up to a point) for Moscow's confrontation with the West.
Moscow is determined to keep arms talks with Washington strictly bilateral; Beijing does not want to join in anyway.
Joint arms production would mark a qualitative leap in defence cooperation, but is some way off.
|
2022-01-27T14:01:21.768Z
|
232,663,601 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3760/CMA.J.ISSN.1673-4904.2016.02.007",
"MAG": "3028980548",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Objective
To improve the quality of life in patients with early penile carcinoma (T1N0M0) after partial excision of penile.
Methods
The clinical data of 21 patients with early penile carcinoma who were treated with partial excision of penile combined with penile lengthening surgery were retrospectively analyzed.
Results
The patients were followed up for 8 months to 5 years. None of patients had recurrence, and there were no external urethral stenosis and postoperative infection. The length of penile at extension state before surgery was 7.6 -11.7 (8.3 ± 1.8) cm, and after surgery was 6.3 -10.5 (7.4 ± 1.4) cm. All the patients were able to urinate in a standing position, 11 cases had normal sexual function, and 6 cases could complete after drug and psychological guidance.
Conclusions
Partial excision of penile combined with penile lengthening surgery is an effective treatment in patients with early penile carcinoma. It can significantly improve the patients' quality of life, and is an effective and feasible treatment method.
Key words:
Penile neoplasms; Retrospective studies; Partial excision of penile; Penile lengthening surgery
|
2022-02-07T22:01:16.521Z
|
162,346,557 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S0041977X00042324",
"MAG": "2044501472",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This, Part B, covers Centamil, Volumes 20 (1921) to 35 (1937). It thus includes the work of a number of great scholars who flourished in the earlier decades of this century, such as MM. Dr. U. V. Caminata Aiyar (see pp. 29-30), S. Vaiyapuri PiUai (pp. 74-5) and P. S. Cuppiramaniya Castiri (pp. 35-7). The indexes are preceded by an excellent introduction that traces the history of Centamil (pp. ix-xvii), and which has a few words about the Maturai Ttamil Ccankam that sponsored it. After the main index of articles arranged according to author (pp. 1—79), are indexes of subject (pp. 80-86), obituary and birthday notices (pp. 87—92), and announcements of recent publications (pp. 93-5), and an alphabetical list of journals and books given under ' Review ' (pp. 96-133). Thislist is of particular interest to any bibliographer or cataloguer. One eagerly awaits the parts A and C that one must assume are to follow. P. R. Subramanian is to be congratulated upon a most useful piece of scholarship.
|
2022-02-09T01:51:19.425Z
|
72,129,456 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1515/labm.1982.6.2.34",
"MAG": "2050591588",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "HYBRID",
"url": "https://www.degruyter.com/document/doi/10.1515/labm.1982.6.2.34/pdf"
}
|
Die freie Thyroxinkonzentration im Serum wurde m/t Hilfe eines neuen Radioimmunoassays, welcher auf dem Prinzip eingekapselter Antikörper beruht, bei verschiedenen Schilddrüsenfunktionszuständen bestimmt und mit einem T4/TBG-Quotienten korreliert (r = 0,82, p < 0,001). Der euthyreote Referenzbereich beträgt 0,7—2,6 ng l dl. Bei Patienten mit dialysepflichtiger Niereninsuffizienz lagen die freien Thyroxinkonzentrationen ebenso im euthyreoten Bereich wie bei Graviden während der drei Trimester der Schwangerschaft Euthyreote Patienten mit autonomen Adenomen oder disseminierter Schilddrüsenautonomie wiesen hingegen wohl noch normale, gegenüber der euthyreoten Kontrollgruppe jedoch signifikant erhöhte FT* Konzentrationen auf,
|
2022-04-01T00:25:23.090Z
|
129,981,859 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.13031/2013.13775",
"MAG": "2176614479",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Processing tomatoes (Lycopersicon esculentum Mill.; cultivar, Heinz 9478) were grown on two
commercial fields: one comprising about 16 acres on the loamy sand and the other comprising about 5 acres on
the clay loam soil. The objectives of this study were to determine the effects of surface and subsurface drip
irrigation and fertigation on yield, quality, and water and nutrient use efficiency of processing tomatoes on
commercial scale. The treatments included non-irrigated control plots with broadcast fertilizer and surface and
sub-surface drip irrigated plots, both with broadcast fertilizer and fertigation (ie. fertilizer applied via drip
lines). Surface and sub-surface drip and/or fertigated plots had consistently higher available soil moisture than
non-irrigated plots throughout the entire 2002 growing season on both loamy and clay loam soils. Both the leaf
petiole sap NO3 -N and K concentrations were within sufficiency values during the month before harvest on
both soils. On the loamy sand soil, marketable tomato yields were increased by 52.3 % and 60.4 % under
surface drip or fertigated (SDI) and sub-surface drip or fertigated (SSDI) plots relative to the non-irrigated
control (NI). Marketable tomato yields under SSDI plots on the loamy sand were increased only by 5.3 %
relative to SDI plots. There was no significant difference in marketable tomato yields between broadcast
fertilizer and fertigation for both SSDI and SDI on the loamy sand. On the clay loam soil, marketable tomato
yields were increased by 86.7 % under SDI plots relative to NI plots, while tomato yields under SSDI plots
were increased by 44.2 % relative to NI plots. Marketable tomato yields on the clay loam under SDI plots were
increased by 29.5 % relative to SSDI plots. The soluble solids of tomato were higher in the non-irrigated plots
than in the drip irrigated and/or fertigated plots for both soils. There were no significant differences on soluble
solids among surface and sub-surface drip irrigated tomatoes with either broadcast fertilizer or fertigation. Drip
irrigation and/or fertigation increased the water use efficiency of tomato by 32 % and 52 % relative to nonirrigation
on the loamy sand and clay loam soils, respectively.
|
2022-07-31T03:01:07.858Z
|
24,758,003 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/PAHCE.2014.6849636",
"MAG": "2091734105",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Recently the somnolence in the drivers has been one of the main causes of car accidents resulting in severe injuries, deaths and significant economic losses. The main purpose of this research is the development of a sleepiness monitoring device for drivers who works for long hours. The proposed monitoring system is composed for a conditioning and acquisition stage for electrooculographs signals (EOG) and control stage dedicated to send and activation alarm. The acquired signals were visualized in a user interface developed in Matlab which also make the signal processing to detect de retina rest potentials for posterior analysis. The EOG signals were reliable enough to establish the threshold levels for the activation of the alarm.
|
2022-12-17T11:12:30.566Z
|
18,908,875 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/DEST.2007.372011",
"MAG": "2081058183",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Most of the payment protocols designed in recent years for mobile payment systems are based on a scenario where all the entities are directly connected to one another. This scenario (formally called "full connectivity scenario") offers advantages to protocol's designers because it allows them to simplify the design and development of payment protocols without losing security guarantees. However, the "full connectivity" scenario does not consider those situations in which the merchant cannot communicate with the acquirer due to absence of Internet access in his/her infrastructure, and the use of other communication technologies is unaffordable due to the inconveniences and costs associated. In order to overcome this restriction and contribute to the progress of m-commerce, in this paper we propose a novel anonymous protocol for a mobile payment system based on a client centric model that employs a digital signature scheme with message recovery using self-certified public keys. As a result, our proposal illustrates how a merchant can sell goods in a secure way even if she can not directly communicate with the acquirer.
|
2022-12-17T04:38:39.482Z
|
164,474,944 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1163/22134379-17104008",
"MAG": "2581224073",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://doi.org/10.1163/22134379-17104008"
}
|
Disclaimer/Complaints regulations If you believe that digital publication of certain material infringes any of your rights or (privacy) interests, please let the Library know, stating your reasons. In case of a legitimate complaint, the Library will make the material inaccessible and/or remove it from the website. Please Ask the Library: http://uba.uva.nl/en/contact, or a letter to: Library of the University of Amsterdam, Secretariat, Singel 425, 1012 WP Amsterdam, The Netherlands. You will be contacted as soon as possible.
|
2022-10-14T00:27:53.665Z
|
49,595,326 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICISC.2018.8398902",
"MAG": "2809834807",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Cloud computing is growing vastly by providing various functions such as global resource scheduling, fault tolerance, reliability and load balancing. cloud security is still a barrier to adoption of this service. Cloud computing has become a familiar term and most used technology around the world. It is a utility computing model which has huge potential and promising innovations that anyone cannot imagine. As more and more businesses are storing there data in cloud, concerns are growing about how safe this environment is. Cloud Security incorporates many security restrictions from the point of view of the customer and cloud providers. In the context of customers, who essentially concerned about that; where the data is stored? Who has the right to see the data? This paper is focused on security issues in cloud computing. In this we use cryptographic algorithm for securing encryption of data over our cloud. We also maintain the integrity of the data using hash codes.
|
2022-12-16T13:23:40.301Z
|
222,036,324 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5694/j.1326-5377.1960.tb68700.x",
"MAG": null,
"PubMedCentral": null
},
"license": "CC0",
"status": "GREEN",
"url": "https://zenodo.org/record/1718589/files/article.pdf"
}
|
Having for the last few years made rather extensive investigations of atypical mycobacteria, I would like to point out that dust seems to be the most likely carrier of infection, provided that atypical acid-fast organisms more or less resembling M2Icobacterium avium are assumed to be identical with the pathogenic strains. Similar organisms have been found in 30 out of 332 tonsils, 14 out of 44 milk specimens, 29 of 44 dust specimens, 9 out of 86 glands from cattle, 21 out of 68 glands from pigs, and 15 out of 101 glands of sheep. Sparrows gave 6 isolations out of 50 examined, and toads (Bufo 7narinus) lout of 30 examined.
|
2022-01-23T04:15:28.580Z
|
110,720,578 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1117/12.978467",
"MAG": "2039191575",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The design of a 10-20 MW, 40 nsec cyclotron auto-resonance maser experiment is presented. The basic components of the CARM are a novel 600 kV, 200 A. field emission gun and a "whispering gallery" mode rippled wall cavity.
|
2022-02-10T04:50:56.854Z
|