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255M
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24
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139,783,138 |
{
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"DOI": "10.1021/ACSABM.9B00053",
"MAG": "2922445509",
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|
The unique luminescence properties of lanthanide(III) ions (Ln3+) in the near-infrared (NIR) range are attracting major attention in view of their exciting applications in the fields of technology, telecommunications, biology, and medicine. One of the main strategies to design luminescent Ln3+-based compounds relies on their sensitization through appropriate chromophoric ligands. The choice of the chromophores depends on the nature of Ln3+ and, as of today, still partially requires experimental trials, in particular, for the creation of luminescent compounds incorporating NIR-emitting Ln3+. The synthesis of organic ligands bearing suitable coordinating and chromophoric units is time- and effort-consuming. We have established a strategy to encapsulate a large number of Yb3+ trifluoromethanesulfonates and 1,n-dihydroxyanthraquinone chromophores in NH2-functionalized 100 nm polystyrene (PS) beads through a rapid swelling process, leading to AQ1,nOH-Yb@PS/NH2 (n = 4, 8). We have shown that 1,n-dihydroxyanthra...
|
2022-10-01T16:42:52.754Z
|
7,906,495 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/1087054713480034",
"MAG": "2054018558",
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},
"license": null,
"status": null,
"url": null
}
|
Objective: This study examined the bifactor models of ADHD in three groups: adolescents from the general community (n = 214), adults from the general community (n = 366), and a clinic sample (n = 245). Method: For the adolescent sample, mothers provided ratings of the ADHD symptoms, and their teachers provided ratings for Emotional Symptoms, Conduct Problems, Hyperactivity, Peer Problems, and Prosocial Behavior. For the adult sample, all adults completed self-ratings of the ADHD symptoms and measures for depression, anxiety, and stress. For the clinic-referred sample, mothers provided ratings of the ADHD symptoms, and they were diagnosed for ADHD, Conduct Disorder/Oppositional Defiant Disorder, anxiety disorders, and depression disorders. Results: The findings for all samples supported the bifactor model, and there were differences in the way the general and specific factors correlated with the external variables. Conclusion: The findings support the validity of the bifactor model.
|
2022-12-17T10:41:02.246Z
|
122,910,333 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4064/SM205-1-5",
"MAG": "2092444651",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Fil: Arias, Maria Laura. Consejo Nacional de Investigaciones Cientificas y Tecnicas. Oficina de Coordinacion Administrativa Saavedra 15. Instituto Argentino de Matematica Alberto Calderon; Argentina
|
2022-12-17T22:09:03.990Z
|
219,971,632 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/1365712719851136",
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},
"license": null,
"status": null,
"url": null
}
|
The possibility of measuring the success of the criminal justice system in distinguishing the guilty from the innocent is often dismissed as impossible or at least impractical. Here I claim to demonstrate that such epistemic measurement would only be difficult. All measurement consists of two steps, the acquisition of observations and their processing through a computational framework. The law has lacked both, but I have recently put forward a computational framework and here I set out how the necessary observations can be obtained. This completes the conceptual foundations necessary for the development of jurisprudence as a social science, for policymaking in the law that is rooted in rational concern for epistemic outcomes, and for us to fulfil the modern, trustworthy and democratic promise that our forebears found in Blackstone’s ratio.
|
2022-12-25T16:49:24.894Z
|
128,775,419 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1029/96EO00224",
"MAG": "2120271988",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
What should undergraduate tectonics students know about earthquakes? The thesis of Exercises in Active Tectonics is that they ought to have some familiarity with quantitative methods for determining earthquake size, location, repeat time, and effect on structures. While this manual is designed to complement Keller and Pinter's text, Active Tectonics: Earthquakes, Uplift, and Landscape, which was published in 1996, it could provide a laboratory component for a variety of introductory courses emphasizing tectonics, geomorphology, or seismology.
|
2022-02-09T15:13:16.861Z
|
187,822,607 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.30554/VENTANAINFORM.24.180.2011",
"MAG": "2917778345",
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},
"license": null,
"status": null,
"url": null
}
|
La edicion No. 24 presenta 10 articulos, seleccionados de los 27 pre-sentados dentro de la convocatoria cerrada en febrero 20 de 2011, procedentes de las universidades colombianas del Valle, del Sinu, Nacional sede Manizales, de Caldas, Pedagogica y Tecnologica, de Narino, Industrial de Santander y obviamente, de Manizales, asi como de la Universidad Pontificia de Salamanca, campus Madrid (Espana).
|
2022-04-30T12:42:49.897Z
|
161,855,289 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1163/22134360-90001112",
"MAG": "2001263349",
"PubMedCentral": null
},
"license": "CCBYNC",
"status": "HYBRID",
"url": "https://brill.com/downloadpdf/journals/nwig/13/1/article-p337_42.pdf"
}
|
In de vergadering van de geschieden letterkundige af deeling der /Co«m^/y^e .d&arferaie va« PFe^wsc/ja/>^w te Amsterdam, gehouden in het begin van Maart 1931, hield Dr. R. van der Meulen te Leiden een verhandeling over den oorsprong en de beteekenis van bovenstaande woorden, welke verhandeling onlangs is opgenomen in de „Mededeelingen der Ifowm&Zzy/se .4£a<fewie va« Wetó«scAa/)̂ >g«, af deeling, Lgtóer&Mn'te", dl. 71. Serie A, No. 2. De aanleiding hiertoe was het volgende: In het jaar 1928 gaf het ffistomcA GewoofccA«̂ > te Utrecht bij gelegenheid van het eeuwfeest van de verovering van de Spaansche Zilvervloot een zeer omvangrijk gedenkboek in het licht over P*<?/ i/^tw e« <fe Zt'Zverfl/ootf, met alle oorspronkelijke bescheiden uit Nederlandsche en Spaansche archieven, bijeenverzameld, toegelicht en uitgegeven door 5. P. Z'ifowore' Naè^r en 4 W Op twee plaatsen in die Spaansche documenten (bl. *41 en *78) komen de twee heel raadselachtige woorden „frejelindes" en „frechlingas" voor, die in algemeenen zin zeker de beteekenis moeten hebben van //o/Zaniers. Doch met zekerheid kan niemand den oorsprong of de afleiding van deze woorden aangeven. Prof. C. F. A. van Dam, hoogleeraar voor de Spaansche taal te Utrecht, aan wien werd opgedragen voor dat
|
2022-05-29T08:17:48.578Z
|
84,136,071 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/EE/12.2.426",
"MAG": "1994162093",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
To determine oviposition preference of the bean leaf beetle, 500 females were given a choice of three soils (sandy clay loam, loamy sand, and organic) at four soil moistures (oven dry, 1,000 mbar, 100 mbar, and saturation). Soil moisture was maintained during the 48-h oviposition period by rope wicks of different lengths. The beetles laid the most eggs in the organic soil, followed by the sandy clay loam, then the loamy sand. Wet and moist treatments were preferred to the dry treatments, with few eggs being laid in the oven-dried soil. Differences in oviposition are related to soil c1oddiness, color, and water holding capacity
|
2022-08-29T05:54:19.171Z
|
124,384,962 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2333/JBHMK.4.32",
"MAG": "2314233138",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A generalized definition of the sth order interactions is given for multiway arrays, from which the similar properties with ANOVA model are derived. The problem of maximization of the highest order correlation function is solved. Moreover, an expression decomposing multiway arrays is shown as a recurrent algorithm that is an extension of the singular value decomposition of matrices. Applications of the decomposition to multiway contingency tables and to the multiway classified data are outlined. This research develops Iwatsubo(1974)and Yoshizawa(1975), and relates with Bahadur's expression and Lancaster's definition of no interaction for contingency tables. The definition and expression given here are more general and constructive than theirs.
|
2022-09-12T22:45:31.292Z
|
251,870,222 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/en15176181",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/1996-1073/15/17/6181/pdf?version=1661773443"
}
|
After approximately 50 years, NASA is restarting efforts to develop nuclear thermal propulsion (NTP) for interplanetary missions. Building upon nuclear engine tests performed from the late 1950s to the early 1970s, the present research and testing focuses on advanced materials and fabrication methods. A number of transient tests have been performed to evaluate materials performance under high-temperature, high-flux conditions, with several more experiments in the pipeline for future testing. The measured data obtained from those tests are being used to validate the Griffin reactor multiphysics code for this particular type of application. Griffin was developed at Idaho National Laboratory (INL) using the MOOSE framework. This article describes the simulation results of the SIRIUS-CAL calibration experiment in the Transient Reactor Test Facility (TREAT). SIRIUS-CAL was the first transient test conducted on NASA fuels, and although the test was performed with a relatively low core peak power, the test specimen survived a temperature exceeding 900 K. Griffin simulations of the experiment successfully matched the reactor’s power transient after calibrating the initial control rod position to match the initial reactor period. The thermal-hydraulics model largely matches the time-dependent response of a thermocouple located within the experiment specimen to within the uncertainty estimate. However, the uncertainty range is significant and must be reduced in the future.
|
2022-10-07T00:44:44.877Z
|
119,099,844 |
{
"externalids": {
"ACL": null,
"ArXiv": "1611.04043",
"DOI": "10.22541/au.156754490.06103020",
"MAG": "2976039824",
"PubMedCentral": null
},
"license": "CCBY",
"status": "HYBRID",
"url": "https://www.authorea.com/doi/pdf/10.22541/au.156754490.06103020"
}
|
ePSproc provides codes for post-processing results from ePolyScat (ePS), a suite of codes for the calculation of quantum scattering problems, developed and released by Luchesse \& co-workers (Gianturco et al. 1994)(Natalense and Lucchese 1999)(R. R. Lucchese and Gianturco 2016). ePS is a powerful computational engine for solving scattering problems, but its inherent complexity, combined with additional post-processing requirements, ranging from simple visualizations to more complex processing involving further calculations based on ePS outputs, present a significant barrier to use for most researchers. ePSproc aims to lower this barrier by providing a range of functions for reading, processing and plotting outputs from ePS. Since ePS calculations are currently finding multiple applications in AMO physics (see below), ePSproc is expected to have significant reuse potential in the community, both as a basic tool-set for researchers beginning to use ePS, and as a more advanced post-processing suite for those already using ePS. ePSproc is currently written for Matlab/Octave, and distributed via Github: this https URL.
|
2022-10-25T09:51:45.533Z
|
24,437,848 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1046/J.1365-2842.2003.00990.X",
"MAG": "1986306545",
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},
"license": null,
"status": null,
"url": null
}
|
The preservation and restoration of severely weakened pulpless teeth is a difficult and relatively unpredictable procedure. This study evaluated the resistance to fracture of experimentally weakened bovine roots internally reconstructed with different filling materials in combination with prefabricated post compared with restored roots that were relatively intact. The roots of 75 mandibular bovine incisors with similar bulks were selected. Of these, 60 were internally prepared to standardized dimensions, thereby simulating weakness. All roots were filled with different restorative materials. The specimens were submitted to the fracture resistance testing with the application of a tangential compressive loading at an angle of 135 degrees in relation to the long axes of the roots. Results indicated statistically significant differences in relation to the root conditions. Weakened roots were less resistant to fracture than were controls. The roots restored with the resin cement demonstrated the lowest fracture resistance values, but statistically significant differences were observed only when compared with those restored by the resin-modified glass-ionomer cement. Resin-modified glass-ionomer cement, polyacid-modified resin composite and resin composite behaved similarly without statistically significant differences among them. None of the materials evaluated were capable of achieving the fracture resistance recorded for unweakened controls.
|
2022-12-17T23:47:11.003Z
|
26,993,864 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1056/NEJMOA032089",
"MAG": "2014273178",
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},
"license": null,
"status": null,
"url": null
}
|
BACKGROUND
We studied the outcomes at school age in children who had participated in a double-blind, placebo-controlled trial of early postnatal dexamethasone therapy (initiated within 12 hours after birth) for the prevention of chronic lung disease of prematurity.
METHODS
Of the 262 children included in the initial study, 159 lived to school age. Of these children, 146 (72 in the dexamethasone group and 74 in the control group) were included in our study. All the infants had had severe respiratory distress syndrome requiring mechanical ventilation shortly after birth. In the dexamethasone group, 0.25 mg of dexamethasone per kilogram of body weight was given intravenously every 12 hours for one week, and then the dose was tapered. We evaluated the children's growth, neurologic and motor function, cognition, and school performance.
RESULTS
Children in the dexamethasone group were significantly shorter than the controls (P=0.03 for boys, P=0.01 for girls, and P=0.03 for all children) and had a significantly smaller head circumference (P=0.04). Children in the dexamethasone group had significantly poorer motor skills (P<0.001), motor coordination (P<0.001), and visual-motor integration (P=0.02). As compared with the controls, children in the dexamethasone group also had significantly lower full IQ scores (mean [+/-SD], 78.2+/-15.0 vs. 84.4+/-12.6; P=0.008), verbal IQ scores (84.1+/-13.2 vs. 88.4+/-11.8, P=0.04), and performance IQ scores (76.5+/-14.6 vs. 84.5+/-12.7, P=0.001). The frequency of clinically significant disabilities was higher among children in the dexamethasone group than among controls (28 of 72 [39 percent] vs. 16 of 74 [22 percent], P=0.04).
CONCLUSIONS
Early postnatal dexamethasone therapy should not be recommended for the routine prevention or treatment of chronic lung disease, because it leads to substantial adverse effects on neuromotor and cognitive function at school age.
|
2022-12-20T02:55:48.895Z
|
73,323,408 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.15277/BJDVD.2015.029",
"MAG": "2102420837",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In February 2015 the National Institute for Health and Care Excellence (NICE) published new guidance (NG3) on the management of diabetes in pregnancy. Care teams need to be aware of this guidance and implement its recommendations. These include preconception care with target HbA1c 48 mmol/mol. Women at risk of gestational diabetes mellitus (GDM) should have a 75 g oral glucose tolerance test (OGTT). Diagnostic criteria for GDM have changed to fasting glucose of 5.6 mmol/L or above or 2 hour glucose of 7.8 mmol/L or above. Glycaemic targets in all diabetic pregnancies have changed to fasting glucose below 5.3 mmol/L (4–5.2 mmol/L if on insulin) and 1 hour postprandial glucose below 7.8 mmol/L if these can be achieved safely. Continuous glucose monitoring and insulin pump therapy should not be used routinely but can be used if glycaemic control is problematic. Capillary ketone testing should be routine for women with type 1 diabetes when hyperglycaemic and for all women with diabetes including, GDM when acutely unwell. More flexibility is offered around recommended delivery timing: 37+0 weeks to 38+6 weeks for women with types 1 and 2 diabetes; prior to 40+6 in GDM (and earlier if complications arise). Postnatal testing following GSM should be by fasting glucose (not OGTT) at 6–13 weeks post partum. Testing later than this can use HbA1c. Introducing these changes will have resource implications, including a likely increase in the number of women diagnosed with GDM.
|
2022-12-20T20:14:01.861Z
|
165,193,004 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.51257/a-v1-bio7070",
"MAG": "2776728865",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Les etudes de la biodiversite, qui recoupent l’ensemble de l’ecologie scientifique, font largement appel a des approches quantitatives tres variees, souvent completement integrees aux problematiques de recherche, tant fondamentale qu’appliquee. La bioinformatique et la biomathematique de la biodiversite s’inserent donc dans une ingenierie de l’ecologie en plein developpement. Cet article propose un tour d’horizon de ces approches quantitatives a l’intention des ingenieurs, en s’appuyant sur les niveaux traditionnels d’organisation des systemes ecologiques: populations, communautes, ecosystemes.
|
2022-02-08T20:04:29.827Z
|
131,909,334 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.22111/IJFS.2019.4551",
"MAG": "2934564095",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this paper, we study the concept of generalized differentiability for fuzzy-valued functions on time scales. Usingthe derivative of the product of two functions, we provide solutions to first order linear fuzzy dynamic equations. Wepresent some examples to illustrate our results.
|
2022-02-09T13:43:24.554Z
|
19,614,973 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1103/PHYSREVB.47.9199",
"MAG": "2089486659",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We report the 4d-XY (X, Y = 5p, 4f, and the conduction band) Auger spectra of clean Gd using a monochromatic photon source with energies above and below the 3d threshold. The spectra with higher hv show the existence of intense spectator-hole Auger transitions. Comparison of these spectra with those obtained with a primary electron source allows detailed interpretation of the various features and explains the unusual spin polarization of the electron-induced spectrum reported earlier.
|
2022-02-12T22:53:05.774Z
|
36,662,146 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1139/o00-014",
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"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Extracellular matrix serves as a scaffold for cells and can also regulate gene expression and ultimately cell behaviour. In this study, we compared the effects of three forms of type I collagen matrix, which differed only in their mechanical properties, and plastic on the expression of transforming growth factor-beta1 (TGF-beta1), matrix metalloproteinase-1 (collagenase), and type I collagen and on the growth and survival of human dermal fibroblasts. These effects were correlated with alterations in cell morphology and organization of intracellular actin. Cells in detached or stress-relaxed matrices were spherical, lacked stress fibres, and showed increased TGF-beta1 mRNA compared to the cells in anchored collagen matrices or on plastic, which were polygonal or bipolar and formed stress fibres. The levels of TGF-beta measured by bioassay were higher in detached and stress-relaxed collagen matrices, than in anchored collagen matrices. Cells on plastic contained little or no immunoreactive TGF-beta, while most cells in collagen matrices were stained. The levels of collagenase mRNA were significantly higher in all the collagen matrix cultures compared to those on plastic, but there were no statistically significant differences between them. Levels of mRNA for procollagen type I were not significantly affected by culture in the collagen matrices. Apoptotic fibroblasts were detected by the TUNEL assay in detached (5.7%) and to a lesser extent in stress-relaxed (2.2%) matrices, but none were observed in anchored collagen matrices or on plastic. These results show that alterations in the mechanical properties of matrix can induce the expression of TGF-beta and trigger apoptosis in dermal fibroblasts. They further suggest that inability to reorganize this matrix could be responsible for the maintenance of the fibroproliferative phenotype associated with fibroblasts in hypertrophic scarring.
|
2022-06-23T03:37:02.867Z
|
120,049,469 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1121/1.411529",
"MAG": "1975950089",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://asa.scitation.org/doi/pdf/10.1121/1.411529"
}
|
To account for higher masked ABR thresholds, input–output (I/O) functions of the ABR were examined. For both aging humans and gerbils, amplitudes of the ABR were smaller and slopes of ABR I/O functions were less steep than those of young subjects. Smaller amplitudes could indicate abnormal function of the brainstem or an altered input to the brain stem from the periphery. Analysis of I/O functions of the compound action potential (CAP) of the auditory nerve of aging gerbils also showed a decrease in slope. Decreases in the slope of the CAP can be attributed to a loss of 10%–30% of spiral ganglion cells, to a reduction in synchronous neural activity of the remaining nerve fibers, and to a reduction of the endocochlear potential. Thus, our hypothesis is that the unusual amounts of masking observed in the ABR of both aging humans and gerbils can be accounted for by age‐related alterations in the auditory periphery. It is also our hypothesis that behavioral measurements of normal quiet and masked thresholds i...
|
2022-07-29T12:15:51.532Z
|
231,792,589 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.31234/osf.io/5tpf2",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://psyarxiv.com/5tpf2/download"
}
|
With development, we acquire a rich body of knowledge about the world. This knowledge is represented by concepts, denoted by words (e.g., juicy, apple, and pear), which are connected by meaningful, semantic links (e.g., apples and pears are similar, and can both be juicy). One potentially powerful driver of this development is sensitivity to regularities with which words co-occur in language. Specifically, language is rich in regularities that can support: (1) Associative semantic links, between words that directly co-occur (e.g., juicy - apple), and (2) Taxonomic semantic links, between words that share patterns of direct co-occurrence (e.g., apple and pear both co-occur with juicy). Here, we investigated the development of learning abilities to form semantic links from these regularities. Results revealed that both four-year-olds and adults formed semantic links based on direct co-occurrence, whereas formation of links based on shared patterns of co-occurrence was robust only in adults. Our findings further suggest that even abilities to form links based on direct co-occurrence (i.e. associative links) may improve with development, which may, in part, account for the protracted development of links based on shared co-occurrence (i.e. taxonomic links). We discuss how these results may provide key insight into how semantic organization develops.
|
2022-09-06T14:36:18.623Z
|
147,182,789 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2466/pr0.1967.20.3c.1084",
"MAG": "2334866288",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Lester (1967a) has criticized research into the fear of death for a failure to investigate factors which might determine the fear of death and for failing to explore implications of particular attitudes toward death. Too often the fear of death in individuals has been examined for its relation to easily available factors such as socioeconomic variables. The present paper is an attempt to move beyond such studies. Lester suggested that the inconsistencies in a person's attitude toward death might have important implications for that individual. It has proved difficult to tie down research into the fear of death to rheorerical notions, but we might speculate that an individual who has inconsistent attitudes toward death might also have an increased fear of death as a result of this inconsistency. The conflict that results from this inconsistency might lead to anxiety and this anxiety might increase the individual's fear of death. Lester ( 1967b) has devised a fear of death scale that enables this hypothesis to be tested. The scale is an equal-interval scale of 21 favorable and unfavorable statements about death. S is required to state whether he agrees or disagrees with the statements. Each statement has a scale value which indicates the degree of fear of death that agreement with the item implies. S's fear of death is the median scale-value of those items with which he agrees. However, it is also possible to obtain from each protocol the range of the scale values with which the individual agrees (the highest scale value minus the lowest scale value; the range is from 1.29 to 10.76). If the hypothesis is rephrased in terms of this scale it can be predicted that Ss who agree with a large range of statements will have a larger fear-of-death score on the scale than Ss who agree with a small range of statements. Protocols were available from 85 undergraduate students enrolled in psychology courses. For each S the median value and the range of values of the statements with which he agreed were calculated. The 21 Ss wirh the largest ranges ( M d n range = 7.01) were compared with the 21 Ss with the smallest ranges ( M d n range = 3 . 4 2 ) . The median fear of death for the groups was 6.52 for the large-range group and 5.51 for the small-range group. When compared by the median test (Siegel, 1956) the large-range group had a significantly higher fear of death ( X 2 = 3.90, p < 0.05). This smdy has shown that Ss who agree to statements about death expressing a large range of attitudes (on a dimension of favorable/unfavorable) have a greater fear of death than Ss who agree wirh a small range of statements. Inconsistency in attitudes toward death then appears to be accompanied by a greater fear of death. That this result is not due to an acquiescence response set is shown by the fact that the association between fear of death scores and the number of items agreed with is not significant ( x 2 = 0.56 on an analysis similar to that used above). However, whether this inconsistency is generalized or specific to death attitudes needs further study. REFERENCES LESTER, D. Experimental and correlational studies of the fear of death. Psychol. Bull., 1967, 67, 27-36. ( a ) LESTER, D. The fear of death of suicidal persons. Psychol. Rep. , 1967, 20, 1077-107s. ( b ) . . SIEGEL, S. Non-parametric statistics for rhe behavioral sciences. New York: McGrawHill, 1956.
|
2022-09-09T02:08:58.246Z
|
137,165,438 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/002199838802200101",
"MAG": "2049245702",
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},
"license": null,
"status": null,
"url": null
}
|
Tests were performed to evaluate the effects of cure and moisture on the moisture ab sorption characteristics and on the mechanical properties of Fiberite 976 resin. The maxi mum moisture content Mm was determined as a function of degree of cure, temperature, and relative humidity. The diffusivity D was determined as a function of degree of cure and temperature. Empirical correlations were established for the maximum moisture con tent and for the diffusivity. The tensile, compressive, and shear strengths and moduli, and the fracture toughness of dry resin were measured at different degrees of cure ranging from 0.6 to 0.95. The tensile, compressive, and shear properties were also measured at dif ferent degrees of cure with resins containing 0 to 4 percent moisture. These data indicate the individual effects of cure as well as the combined effects of cure and moisture on the mechanical properties.
|
2022-09-09T20:18:32.246Z
|
224,827,280 |
{
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"ArXiv": null,
"DOI": "10.1021/acs.jproteome.0c00671",
"MAG": "3093480458",
"PubMedCentral": "7640978"
},
"license": null,
"status": "GREEN",
"url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7640978"
}
|
The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has impacted a large portion of the world population. From a virus genetic perspective, a recent study described what genomic data revealed about the origin and emergence of SARS-CoV-2, proposing stronger action against illegal wildlife trade. In the current “big data” era, an increasing number of large-scale, multidimensional omics data sets were publicly available. Herein, we review how human genetics tells us about the transmission, pathogenesis, susceptibility, severity, and drug prioritization of COVID-19. We further drafted a genetic roadmap of COVID-19, which was also expected to be applicable to other viruses with known receptors. Our review provides insights into the way of understanding a pandemic from a human genetic perspective.
|
2022-12-02T12:15:55.383Z
|
235,649,587 |
{
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"ArXiv": null,
"DOI": "10.1515/zrgr-2021-0008",
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"url": null
}
|
Abstract Parakatatheke and last wills: on the background of D. 32.37.5. Already Hans Julius Wolff refused the idea of a hermetical isolation between Roman law and local (provincial) legal practice in everyday life. Following his trace, this contribution will show that legal intercourse between different classes of provincial populace was far more intensive than generally assumed. Focusing on the period before the Constitutio Antoniniana (212 AD), a detailed exegesis of a unique decision of Scaevola follows. The Roman jurist delivers a paradigmatic case: He settles a dispute in which the Greek formula of parakatatheke was used by a Roman citizen for disposing about his assets on death. In fact, the legal act should be considered ineffective under Roman law. However, Scaevola looked for ways to enforce the claim. Roman law and provincial legal custom: Scaevola’s decision sheds a new light on the creative approach of Roman jurisdiction regarding foreign legal thoughts.
|
2022-12-16T13:42:06.635Z
|
54,804,694 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1299/JAMDSM.2.246",
"MAG": "2110994481",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The X-ray lithography of uses synchrotron radiation is one of the microprocessing structure fabrication technology. In X-ray lithography, precision of the fabricated structure is influenced by precision of the X-ray mask considerably. Conventionally, the X-ray mask was fabricated with UV lithography. However, it is difficult to fabricate the highly precise X-ray mask because of the tapering X-ray absorber. We introduces the ability of Si dry etching technology into UV lithography in order to fabricate untapered, high precision X-ray masks containing rectangular patterns. This new X-ray mask fabrication method uses a high-precision microstructure pattern formed by Si dry etching, thereby fabricating high aspect ratio, narrow line width resist microstructures that cannot be achieved by any conventional technology. An Au for the X-ray absorber is made to the groove of the structure, and it is formed by electroplating. The silicon substrate itself is used as seed layer and the structure is fabricated with the photo resist whose resistance is higher than silicon. It can be expected the gilding growth from only the bottom layer. High-density Au functions sufficiently as an absorber. Au plating was formed only from the base of the structure ditch and could bury Au of thickness 3.5µm in a narrow place of 2.7µm in width well. The fabricated structure using X-ray lithography. Highly-precise rectangular structure could be fabricated.
|
2022-12-17T07:49:20.471Z
|
132,245,893 |
{
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"ArXiv": null,
"DOI": "10.1017/S0043174500083934",
"MAG": "2515506113",
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},
"license": null,
"status": null,
"url": null
}
|
A 7-yr study was conducted to investigate successional dynamics of herbaceous vegetation after control of western juniper (Juniperus occidentalis Hook.) trees with picloram (4-amino-3,5,6-trichloropicolinic acid) pellets. Downy brome (Bromus tectorum L. # BROTE) rapidly dominated areas under dead tree canopies with an accompanying yield increase from almost none to about 1400 kg/ha within 4 yr after treatment. In the interstitial zone between tree canopies, a dramatic shift in herbaceous species occurred with tree control. Annual broadleaf species decreased, downy brome increased, and medusahead [Taeniatherum asperum (Sim.) Nevski # ELYCM] gradually became dominant. Total yield of herbaceous vegetation in the interstitial zone increased dramatically after picloram treatment, especially where few shrubs occurred. Available soil moisture, litter accumulation and decay after picloram treatment, and N in the surface layer of the soil affected responses of herbaceous vegetation, especially under dead tree canopies. Responses of annual weedy species to western juniper control emphasize the need for comprehensive manipulation of all components of the vegetation when range improvement is attempted.
|
2022-12-20T12:46:15.836Z
|
29,051,550 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1021/BI9606859",
"MAG": "2043564320",
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},
"license": null,
"status": null,
"url": null
}
|
Cellular activation, accompanied by elevation of cytoplasmic Ca2+ levels, can induce a progressive loss of plasma membrane phospholipid asymmetry, resulting from increased transbilayer movement (flip-flop) of phospholipids. While this process has been demonstrated in a variety of different cells, it is most active in blood platelets. In order to test whether this lipid scrambling process is mediated by a membrane protein, platelet membranes were solubilized in cholate and fractionated by anion exchange chromatography, and fractions were reconstituted into phospholipid vesicles by detergent dialysis in the presence of small amounts of fluorescent (NBD) phospholipids. Using dithionite reduction to monitor the transbilayer location of NBD phospholipids, it was shown that addition of Ca2+ and ionomycin to vesicles reconstituted with a particular fraction results in transbilayer movement of the fluorescent phospholipid analogs from the vesicle's inner to outer leaflet. Lipid vesicles reconstituted in the absence of membrane protein, or reconstituted with another platelet membrane protein fraction, were devoid of this activity. Heating the active fraction or incubating it with pronase or the SH reagent pyridyldithioethylamine markedly diminished the ability of the vesicles to translocate fluorescent phospholipid analogs across the bilayer in response to Ca2+ and ionophore. These results argue that a membrane protein (or proteins) from blood platelets is required to catalyze Ca2+-induced transbilayer movement of phospholipids, suggesting its (or their) involvement in the loss of lipid asymmetry that can occur during cellular activation.
|
2022-12-20T21:59:44.290Z
|
154,019,098 |
{
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"ArXiv": null,
"DOI": "10.2139/ssrn.1830365",
"MAG": "1972627978",
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},
"license": null,
"status": null,
"url": null
}
|
Employing a resource-dependence theoretical framework, we analyze a set of recently awarded contracts between the Environmental Protection Agency and various suppliers to determine how joint dependence, supplier dependence, and government dependence affect contract design, and specifically the decision to use a cost-plus (flexible) contract. Findings provide evidence that organizations choose contract designs that will reduce uncertainty related to securing critical resources. However, different dimensions of dependence have different effects: (1) higher levels of joint dependence lead to more flexible governance forms; (2) the lack of alternative suppliers is a more important factor than high levels of financial dependence; and (3) the parties involved in government procurement are likely to perceive government as a unique type of organization, which in turn has implications for contract design choices. We conclude with managerial strategies for restructuring power-dependence relationships to achieve the contract design most likely to yield a surplus in the exchange.
|
2022-12-26T20:16:51.582Z
|
201,168,886 |
{
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"ArXiv": null,
"DOI": "10.4000/CHRHC.11241",
"MAG": "2966474004",
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"license": null,
"status": null,
"url": null
}
|
Dans cet ouvrage, Gilles Candar, grand specialiste de l’histoire des gauches francaises, ne s’interesse pas a la figure iconique du socialisme, Jean Jaures – auquel il a consacre avec Vincent Duclert une tres belle biographie erudite en 2014, qui est devenue depuis une reference en histoire politique –, mais a une personnalite qui a laisse moins de traces dans la memoire collective, Edouard Vaillant. En 2015, l’auteur avait deja apprehende, sous la forme d’un essai, cet homme incarnant « le s...
|
2022-02-08T05:13:03.197Z
|
70,874,918 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.20344/AMP.2621",
"MAG": "1594654912",
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"license": null,
"status": null,
"url": null
}
|
Diarrhoea is defined either clinically or pathophysiologically. Some epidemiological issues are considered in a global as well as in a national perspective. The main etiologies and pathophysiological mechanisms are referred. Some important natural defenses against intestinal infection are pointed out. Clinical manifestations are briefly described. The main therapeutical guidelines are discussed. Breast milk is referred to as one of the most important preventive measures against acute infectious diarrhoea.
|
2022-02-11T11:16:48.221Z
|
2,892,755 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4021/jocmr613w",
"MAG": "2098520010",
"PubMedCentral": "3194016"
},
"license": "CCBYNC",
"status": "HYBRID",
"url": "https://doi.org/10.4021/jocmr613w"
}
|
Background The question of whether children and infants have memory capabilities similar to adults has long been of interest. Until recently, it was thought that compared to adults, infants have very limited memory processing abilities. Knowledge about factors affecting a child's memory abilities can help families (specifically mothers) behave in a manner that best benefits their children in language and memory skills. The present study examines one factor that may underlie a child's memory capabilities; namely the mother's narrative style. Methods Convenience sampling was used to select participants. Forty healthy children (mean age of 31.55 months, range 25-37 months) and their mothers were entered into the study. All participants were native Turkish speakers, from similar socioeconomic status backgrounds. Memory was assessed by a modified version of the Magic Shrinking Machine. Narrative style was assessed by the mother "reading" a Frog Story; a picture book with no words in it. Children were then grouped according to their mother's level of narrative style. Children's language skills were measured via the Turkish form of the CDI (Communicative Development Inventory) which was translated to Turkish as TIGE. Results To explore the relationships between mothers' narrative styles and children's memory and language skills and between children's language skills and memory capabilities, linear regressions were run. There were no significant correlations among any comparisons (P > 0.05). Conclusions Children's language skills do not improve according to their mothers' narrative styles, and children do not show better memory abilities when mothers use more words and longer sentences. In order to have a better understanding of these relationships, future research that includes several more variables is needed. Keywords Child; Mother; Memory; Narrative style
|
2022-02-13T13:14:16.330Z
|
52,988,533 |
{
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"ArXiv": null,
"DOI": "10.1109/FUZZ-IEEE.2018.8491483",
"MAG": "2897540715",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper suggests an interval fuzzy inference system (iFIS) modeling approach for interval-valued time series forecasting. Interval-valued data arise quite naturally in many situations in which such data represent uncertainty/variability or when comprehensive ways to summarize large data sets are required. The method comprises a fuzzy rule-based framework with affine consequents which provides a (non)linear framework that processes interval-valued symbolic data. The iFIS antecedents identification uses a fuzzy c-means clustering algorithm for interval-valued data with adaptive distances, whereas parameters of the linear consequents are estimated with a centre-range methodology to fit a linear regression model to symbolic interval data. iFIS forecasting power, measured by accuracy metrics and statistical tests, was evaluated through Monte Carlo experiments using synthetic interval-valued time series with linear and chaotic dynamics. The results indicate a superior performance of iFIS compared to traditional alternative single-valued and interval-valued forecasting models.
|
2022-03-08T11:10:31.358Z
|
204,937,688 |
{
"externalids": {
"ACL": null,
"ArXiv": "1202.1881",
"DOI": "10.5121/ijist.2012.2104",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://doi.org/10.5121/ijist.2012.2104"
}
|
In the view of massive content explosion in World Wide Web through diverse sources, it has become mandatory to have content filtering tools. The filtering of contents of the web pages holds greater significance in cases of access by minor-age people. The traditional web page blocking systems goes by the Boolean methodology of either displaying the full page or blocking it completely. With the increased dynamism in the web pages, it has become a common phenomenon that different portions of the web page holds different types of content at different time instances. This paper proposes a model to block the contents at a fine-grained level i.e. instead of completely blocking the page it would be efficient to block only those segments which holds the contents to be blocked. The advantages of this method over the traditional methods are fine-graining level of blocking and automatic identification of portions of the page to be blocked. The experiments conducted on the proposed model indicate 88% of accuracy in filtering out the segments.
|
2022-07-10T02:17:48.040Z
|
34,010,771 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.17795/IJO-5463",
"MAG": "2511592477",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Context: One of the most important aims in orthodontic treatment is to apply a light continuous force to achieve maximum ef- fective tooth movement with minimal side eects (optimal tooth movement). It is obvious that elastomeric chains are the most popular method of space closure, but they undergo force decay during time. Force decay behavior of elastomeric chains is influ- enced by various factors. It is crucial for every practitioner to know about these products and factors aecting them. Evidence Acquisition: So we searched English articles published in Pubmed between 2005 - 2016 with keyword "orthodontics, elastomeric chain". Results: 25 articles were selected for comprehensive reading according to the inclusion criteria. Some factors such as aging process, production technique, pre-stretching eect, design and type of chains, in-vivo eects and microbial contamination were discussed. Conclusions: By reviewing these articles, we know more about force decay pattern of elastomeric chains. Most of articles said the same force decay pattern for these elastomeric products. We know more about environmental conditions aect their features. This can help practitioners to use chains , in a better way.
|
2022-09-02T03:06:15.020Z
|
12,138,619 |
{
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"ArXiv": null,
"DOI": "10.1109/ICEICE.2012.356",
"MAG": "1621331350",
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},
"license": null,
"status": null,
"url": null
}
|
This paper proposes a new method to obtain an improved 2-order Chebyshev chaotic sequence, along with the theoretical analysis and the simulation experiments with the sequence. Compared with m sequence in the balance property and the run-length property, the sequence maintains good performance. The findings of theoretical analysis and the experiments show that the improved sequence is better than m sequence application in spread spectrum communication system.
|
2022-09-09T09:02:34.421Z
|
251,172,100 |
{
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"ArXiv": null,
"DOI": "10.35634/2412-9518-2022-32-2-119-129",
"MAG": null,
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},
"license": null,
"status": "BRONZE",
"url": "https://journals.udsu.ru/biology/article/download/6940/6163"
}
|
The abnormally warm and dry summer was the main feature of the year 2021. The average temperature of June (21,4) was the record for the whole period of instrumental meteorological observations since 1752. The phenological anomalies were evident first of all in the early dates of phenostages of the year, since the third stage of subseason "Height of Spring" till the first stage of subseason "Abatement of Summer", and especially very early dates of subseason of "Full Summer", which became the record or close to record ones. So, the warming of the climate of Saint Petersburg is continuing and strengthening. In such condition after the winter 2020/21 the majority of trees and shrubs in Peter the Great Botanic Garden (Saint Petersburg, Russia) survived the winter without damages or with small damages not more than half of annual growth. The summer drought, accompanied by hot weather, caused the early yellowing and falling of leaves on many trees and shrubs which happened to be not hardy to drought. The phenological monitoring and timely publishing of results of observations is of important significance in conditions of climatic changes.
|
2022-09-23T00:18:44.703Z
|
209,524,225 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1089/thy.2019.0202",
"MAG": "3001920222",
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},
"license": null,
"status": null,
"url": null
}
|
is not required.
|
2022-12-17T09:22:08.814Z
|
20,390,035 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1183/09031936.01.00073401",
"MAG": "2100765934",
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},
"license": null,
"status": "BRONZE",
"url": "https://erj.ersjournals.com/content/erj/18/2/286.full.pdf"
}
|
It was hypothesized that hypoxia may inhibit nitric oxide (NO) production by reducing the availability of endothelial NO synthase (NOS III) substrate. To evaluate the effect of L-arginine on the NO release in high altitude, 11 subjects were infused with L-arginine (0.5 g x kg(-1)) during 30 min in normoxia and after 36 h at 4,350 m (hypoxia). The L-citrulline and cyclic guanosine monophosphate (cGMP) concentrations were measured to investigate NO synthesis and guanylyl cyclase activity respectively. L-citrulline concentration, arterial oxygen saturation (Sa,O2), systemic blood pressure, heart rate and acute mountain sickness (AMS) score were measured at rest and 15, 30 and 45 min after starting infusion. The results showed that baseline L-citrulline was lower in hypoxia (p<0.05). L-arginine infusion increased L-citrulline concentration in both conditions. However, in hypoxia L-citrulline concentration remained lower than in normoxia (p<0.05). The concentration of cGMP was lower in hypoxia (p<0.05). In hypoxia, Sa,O2 increased from 15 min after the start of the infusion to 45 min (p<0.05). Blood pressure and heart rate were not affected by L-arginine infusion. Subjects who experienced symptoms of AMS showed a slight decrease in AMS score with L-arginine. The decreased L-citrulline suggests a hypoxia-induced impairment of nitric oxide synthase III or a decrease in L-arginine availability. The improvement of arterial oxygen saturation by pretreatment with L-arginine could be ascribed to an enhancement of the ventilation/perfusion ratio. Collectively, these results are consistent with a decrease in nitric oxide production in hypoxia that could be antagonized by supplying nitric oxide synthase cosubstrate.
|
2022-12-23T02:09:14.141Z
|
46,278,761 |
{
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"ArXiv": null,
"DOI": "10.3233/IP-140341",
"MAG": "1531846075",
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},
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}
|
With the advancements in information technologies and internet applications, electronic government (e-government) gained prominence among many governments around the world. As a developing country, in Turkey, e-government has been a priority subject in delivery of government services. E-movable system, which was initiated in 2007 in public institutions, is an example to e-government applications in Turkey. The purpose of this study is to measure the success of Turkish e-movable system from the perspectives of employees in public institutions who use this system. The study developed Technology Acceptance Model for Using E-Movable System (TAMUeM) based on technology acceptance model (TAM) to measure the success of e-movable system. The model proposed consists of seven constructs including information quality, service quality, perceived usefulness, perceived ease of use, attitude towards using and behavioural intention to use. The results revealed significant connections between the seven constructs of the model. All hypotheses were supported. The results imply that e-movable system is significantly accepted in public organizations and that it can be extended to be applied in private sector.
|
2022-12-23T08:17:31.968Z
|
113,220,841 |
{
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"ArXiv": null,
"DOI": "10.4013/SDRJ.2010.33.04",
"MAG": "2305222614",
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},
"license": null,
"status": null,
"url": null
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|
The article starts from the sociocultural and technological contexts --interfering in the timing of senses, sensations and bodily affections-- in order to question the processuality of fashion, its historical time, its mutations and its contemporary affi rmation as an autophagic system from which the becoming of culture emerges. It discusses critically the phenomenon of fashion as an operator of consumption and a producer of trends.
|
2022-02-10T02:38:35.193Z
|
76,399,141 |
{
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"ArXiv": null,
"DOI": "10.7600/JSPFSM.63.169",
"MAG": "2328863301",
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},
"license": null,
"status": null,
"url": null
}
|
Habitual moderateto vigorous-intensity physical activity positively impacts lower extremely performance in older adults. However, little is known whether habitual sedentary behaviour time independently impacts lower extremity performance. The purpose of this cross-sectional study was to identify whether sedentary behaviour time is associated with lower extremity performance independent of moderateto vigorous-intensity physical activity time in older adults. Eight-hundred-and-two community-dwelling older Japanese adults (72.5 ± 5.9 years) participated in this study. Sedentary behavioir time and moderateto vigorousintensity physical activity time were assessed using a uniaxial accelerometer. Lower extremity performance was assessed by repeated chair stand, single leg stance, and timed up and go tests. Jonckheere terpstra trend test and Spearman rank correlation coefficient were used to identify the single relation between sedentary behaviour time and lower extremity performance. A hierarchical multiple regression analysis was used to identify whether sedentary behaviour time is associated with lower extremity performance independent of moderateto vigorous-intensity physical activity time. Results of single relation analysis showed there were negative associations between sedentary behaviour time and all lower extremity performance tests. Multivariable analysis indicated that sedentary behaviour time was not significantly associated with any lower extremity performances but moderateto vigorous-intensity physical activity time was positively associated with all lower extremity performance tests. In conclusion, sedentary behaviour time would be less useful than moderateto vigorous-intensity physical activity time as an indicator for modifying habitual behavior to maintain good lower extremity performance in community-dwelling older adults. Jpn J Phys Fitness Sports Med, 63(1): 169-176 (2014)
|
2022-02-11T06:25:05.144Z
|
189,829,983 |
{
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"ArXiv": null,
"DOI": "10.1017/S0261444800011757",
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},
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"url": null
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|
The papers in this volume are the work of a group of theorists who view language essentially as a mode of human development, both individual and social, and reject the static, non-developmental models of language which have dominated linguistic theory for the past 50 years. These papers explore many implications of the develop- mentalist approach in such fields as psycholinguistics, phonology, pragmatics, semantics and philosophy of language. information and educational teacher learner-centred methodology; literature teaching; English for Specific Purposes; key issues.
|
2022-07-13T14:54:33.917Z
|
154,314,412 |
{
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"ArXiv": null,
"DOI": "10.1515/bap-2012-0038",
"MAG": "2090615491",
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"url": null
}
|
This paper considers the relationship between assessments of institutional quality in developing countries and the innovative activities of multinational corporations. Firm entry mode literature has established links between domestic institutions and ownership equity patterns among multinationals, but institutionalist analyses have not adequately addressed the types of activities pursued by multinational firms. I argue that in addition to various socioeconomic indicators, the quality of domestic political institutions in developing countries is an important determinant of local innovative activity. I argue that institutional quality in host countries reinforces consistent patterns of interaction between states and firms, leading to reduced risk of technological expropriation and other undesirable outcomes for firms. I test this argument by examining the impact of institutional assessments, carried out by firms themselves and by outside observers, on R&D effort among multinationals, using firm-level surveys conducted in developing countries between 2002 and 2005. The multilevel empirical analysis suggests that multinational firms are likely to both locate R&D activities and pursue them intensively in developing countries with well-regarded institutions, and that the impact of institutional variables is more significant than other likely predictors, such as education levels in host countries.
|
2022-09-06T13:10:41.342Z
|
154,722,991 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/09595237100185181",
"MAG": "2065395147",
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},
"license": null,
"status": null,
"url": null
}
|
Whitbread M. (1971) A framework for the efficient production of airport services, Reg. Studies 5, 121–134. Events leading to the recent decision on the Third London Airport indicate that more efficient airport planning procedures should be adopted in the United Kingdom. This paper discusses some general principles of the use of resources which could be applied to the planning of new airport investments. Environmental amenities are seen as resources having a value to members of society and which are often foregone by airport operations. The main improvements to existing airport planning procedures would result from more effective incorporation of potential amenity losses, as well as consumer accessibility and other factors, into project design and evaluation. Two decision-making models are outlined which could lead to such improvements. In the favoured model the principal beneficiaries of airport facilities (passengers and other users) must pay for the full opportunity costs, including amenity losses, of t...
|
2022-09-08T10:57:50.596Z
|
184,762,944 |
{
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"ArXiv": null,
"DOI": "10.24289/ijsser.273012",
"MAG": "2593534226",
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},
"license": "CCBY",
"status": "GOLD",
"url": "https://dergipark.org.tr/en/download/article-file/254092"
}
|
Kurumlarin varligini tehdit eden gelecekleri konusunda olumsuz etkiler yaratabilen krizler, yurutulecek basarili kriz iletisim stratejileri sayesinde atlatilabilmektedir. Kriz iletisiminde olasi kriz unsurlarinin onceden ongorulmesi ve bunlara yonelik yol gosterici onlemlerin alinmasi kriz oncesi proaktif kriz iletisimi olarak tanimlanirken, krizin ortaya cikmasi ile algilari etkilemek, imaji yeniden olusturmak ya da pozitif yonde etkilemek icin yurutulen calismalar reaktif kriz iletisimi olarak tanimlanmaktadir. Bu calisma kapsaminda halkin buyuk bir cogunlugunun, gerek sosyal bir aktivite gerekse, bos zaman degerlendirme ya da eglence amacli toplandiklari alisveris merkezlerinin proaktif ve reaktif kriz iletisim stratejileri degerlendirmistir. Alisveris merkezlerinde (AVM) yasanilabilecek olasi krizlere yonelik izlenen kriz iletisim stratejileri irdelenmistir. AVM yoneticileri ile yapilan gorusmede kriz durumlarina yonelik proaktif ve reaktif bir kriz iletisim stratejilerinin olup olmadigi, nasil bir iletisim stratejisi izledikleri sorgulanmistir. Bu calismanin amaci AVM yonetimlerinin olasi krizlere yonelik kriz iletisim stratejilerinin neler oldugunu tespit etmektir. Gunumuzde yasanilan olumsuzluklar karsisinda halkin guvenini sarsan ya da hayatini tehdit eden olumsuzluklara karsin AVM yonetimlerinin ne kadar bilincli bir strateji izleyip izlemedikleri sorgulanmistir. Buna bagli olarak var olan tabloda yer alan eksiklikler ya da artilar saptanmistir.
|
2022-08-24T10:33:09.531Z
|
145,300,871 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1353/lar.2015.0038",
"MAG": "2110338018",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Latin American global cities have embraced international tourism as a pillar of economic development. Even as tourism has recently grown dramatically, some cities have succeeded and others have failed at capturing international tourists and delivering benefits to the population. This article examines the role of new public institutions (tourism ministries) and social structure from 2000 to 2010 in Buenos Aires, Havana, and Rio de Janeiro. Based on extensive fieldwork and interviews, the evidence shows that both policy choices and social structure shape the composition of international tourism. Prospect theory and economic crisis help explain the emergence of entrepreneurial and innovative bureaucracies. Buenos Aires is an example of innovative inclusive tourism, Havana exhibits innovative disarticulated tourism, and Rio de Janeiro features stagnant urban enclave tourism.
|
2022-09-01T01:04:18.597Z
|
9,900,392 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1046/J.1526-0968.1999.00208.X",
"MAG": "1987841899",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A patient with acquired hemophilia complicated with chronic renal failure and lung tuberculosis was successfully treated by consecutive plasma exchange (PE). A 71-year-old man with serious bleeding tendency showed low coagulation factor levels and a high titer of factor VIII (FVIII) inhibitor, and he was diagnosed with acquired hemophilia. Because of the complication of active lung tuberculosis, instead of immunosuppressive therapy, he undertook a series of PE with fresh frozen plasma replacement for 3 months. After the start of PE, his bleeding symptoms and activated partial thromboplastin time (APTT) improved gradually according to the decrease in FVIII inhibitor levels. These results suggest that PE is an effective therapeutic tool for refractory acquired hemophilia.
|
2022-09-15T00:01:45.600Z
|
53,628,946 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/9781118901731.iecrm0040",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The conjoint measurement approach (also referred to as conjoint analysis or trade-off analysis) is an empirical research method for studying individual preferences or (purchase) decisions, determining trade-offs, segmenting groups with similar values, and simulating reactions to novel products or scenarios. The theoretical groundwork of conjoint analysis reaches back to the 1920s, but the foundation for the applied conjoint measurement approach was laid in the 1960s by the mathematical psychologist Luce and the statistician Tukey (Luce & Tukey, 1964). The methodwas—and still is—predominantly used inmarketing research for designing and positioning new products, estimating product demand or pricing decisions (Green & Srinivasan, 1978; Kohli & Sukumar, 1990). Today, conjoint studies are established in various other scientific disciplines such as health care (Ryan&Farrar, 2000), transportation (Bunch, Bradley, Golob, Kitamura, & Occhiuzzo, 1993), or environmental studies (Álvarez-Farizo & Hanley, 2002). In contrast, in communication science the conjoint measurement approach is rarely used so far, although it could provide valuable contributions to communication science research issues. Hence, the aim of this entry is an introduction to conjoint analysis and an overview of its application in the field of communication science.
|
2022-10-30T15:56:20.070Z
|
33,916,955 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1145/3148011.3154474",
"MAG": "2780474713",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper addresses the problem of taxi-passenger queue context prediction using neighborhood based methods. We capture the taxi drivers' knowledge based on how they move in terms of temporal driver-knowledge deviation (TDKD). Then a TDKD-aided feature importance scheme is introduced for neighborhood based queue context prediction. We apply our proposed scheme to predict different queue contexts at a busy international airport in New York. We argue that the incorporation of taxi drivers' knowledge for calculating feature importance significantly improves the quality of selected neighborhood, thus boosting the prediction accuracy. The experimental results demonstrate the effectiveness of our proposed TDKD-aided feature importance scheme for neighborhood based taxi-passenger queue context prediction.
|
2022-11-02T22:53:21.475Z
|
101,090,763 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4164/sptj.31.338",
"MAG": "2313902599",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://www.jstage.jst.go.jp/article/sptj1978/31/5/31_5_338/_pdf"
}
|
The pulverizing behavior of coals in organic solvents has been studied by a homogenizer-type pulverizer. The pulverized coal powder exhibited a particle size distribution consisting of coarse and fine particles divided at around 70μm. Illinois No. 6 coal was pulverized easily in solvents such as toluene and hexane which hardly swelled the coal, but it was not easy to pulverize in solvents such as acetone and ethanol which swelled the coal. The pulverizing characteristics also depended on the coal rank. The low rank coals, Wandoan and Wabamun, were hard to pulverize in toluene. Vitrinites and inertinites were condensed in the fine and coarse particles, respectively.
|
2022-02-10T10:41:40.484Z
|
39,186,483 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1600-0528.2008.00425.x",
"MAG": "2029918247",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
BACKGROUND
Nursing caries is considered to be problematic by dental health professionals. In their zealousness to solve the nursing caries problem dental health professionals forgot to ask the question: 'Why do mothers persist in prolonged bottle feeding?'
AIM
To use grounded theory procedures and techniques to analyse the qualitative data obtained from mothers and to generate an emerging theory of prolonged bottle feeding.
METHOD
A series of individual in-depth interviews were conducted with 34 mothers of children with nursing caries. The children were aged between 3 and 4 years. Data were analysed using the grounded theory procedures and techniques of open and selective coding.
RESULTS
The core category or the mothers' main concern that emerged from the data was conceptualized as 'buying time'. The feeding bottle bought time away from crying children by silencing them but also bought extra time with the child. Therefore, two different behavioural styles or categories of buying time emerged. These were: (i) to buy time away from the demands of their crying toddlers (instant solutions) and (ii) to buy extra time with their 'toddler-babies' (double-binding). The feeding bottle acted as an 'instant solution' as on seeing the bottle the child would instantly 'stop crying' and peace would reign. Double-binding described how the feeding bottle was used to buy extra time for 'babyhood closeness' between mother and child while exposing the mothers' harsh rejecting behaviours.
DISCUSSION
An understanding of the time concerns that the mothers experienced when caring for their young children and how they resolve them provides an important insight into the reasons for prolonged bottle feeding.
|
2022-09-24T15:28:46.400Z
|
232,263,060 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/inthealth/ihab012",
"MAG": null,
"PubMedCentral": "8643428"
},
"license": "CCBYNC",
"status": "HYBRID",
"url": "https://academic.oup.com/inthealth/advance-article-pdf/doi/10.1093/inthealth/ihab012/36621329/ihab012.pdf"
}
|
Abstract Background To explore the influencing factors for in-hospital mortality in the neonatal intensive care unit (NICU) and to establish a predictive nomogram. Methods Neonatal data were extracted from the Medical Information Mart for Intensive Care III (MIMIC-III) database. Both univariate and multivariate logit binomial general linear models were used to analyse the factors influencing neonatal death. The area under the receiver operating characteristics (ROC) curve was used to assess the predictive model, which was visualized by a nomogram. Results A total of 1258 neonates from the NICU in the MIMIC-III database were eligible for the study, including 1194 surviving patients and 64 deaths. Multivariate analysis showed that red cell distribution width (RDW) (odds ratio [OR] 0.813, p=0.003) and total bilirubin (TBIL; OR 0.644, p<0.001) had protective effects on neonatal in-hospital death, while lymphocytes (OR 1.205, p=0.025), arterial partial pressure of carbon dioxide (PaCO2; OR 1.294, p=0.016) and sequential organ failure assessment (SOFA) score (OR 1.483, p<0.001) were its independent risk factors. Based on this, the area under the curve of this predictive model was up to 0.865 (95% confidence interval 0.813 to 0.917), which was also confirmed by a nomogram. Conclusions The nomogram constructed suggests that RDW, TBIL, lymphocytes, PaCO2 and SOFA score are all significant predictors for in-hospital mortality in the NICU.
|
2022-12-10T09:31:25.831Z
|
241,606,341 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICCCNT51525.2021.9579940",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Natural Language Processing (NLP) is one of the greatest familiar field of Artificial Intelligence. Bangla text classification is become a significant problem due to the availability of textual documents. So, it's high time to solve this problem for better information organization and knowledge management. This study identifies the type of Bangla sentence from a human story: exclamatory or interrogative text document. Several machine learning approaches are applying to the dataset and identify the sentence from the text document. Regulating data is collected from various platforms such as story, Bengali's blog, conversation, etc. To get the output, we need to go through hard work as data cleaning, preprocessing, tokenized by the Countervector, etc. After processing data for the feeding model, we conduct various classification approaches to predict the sentence and provide high accuracy for deciding the result. Among all the approaches, Random Forest and XGBoost provide the highest accuracy of 96.39% in parallel. This study also provides the advantage of sentimental analysis by detecting the type of document in further implementation.
|
2022-12-29T19:03:23.946Z
|
253,537,972 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/app122211501",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2076-3417/12/22/11501/pdf?version=1668750925"
}
|
This paper aims to provide a novel control framework for exactly regulating the output voltage of floating interleaved boost converters (FIBCs), which have been widely employed in fuel cell applications in recent years. Firstly, a mathematical model of the FIBC is constructed according to Kirchhoff’s current and voltage loop principles. Then a cascade control structure with a current inner loop and voltage outer loop is developed to achieve the desired voltage regulation performance. The current controller is established based on the generalized super-twisting algorithm (GSTA) to ensure that the inductor current exactly follows the current reference, which is generated by the outer loop. Meanwhile, an active disturbance rejection control (ADRC) framework is utilized for robustly regulating the output voltage despite the presence of input variation and load change in the voltage control loop based on a nonlinear continuous GSTA-based extended state observer (GSTA-based ESO). The stability of a closed loop system based on the GSTA controller and the GSTA-based ESO is conclusively proven using the Lyapunov theory. The Simscape model of the FIBC is developed, which is used to verify the feasibility and the appropriateness of the recommended control algorithm. Finally, numerical simulations are carried out to demonstrate the effectiveness of the proposed method compared to several previous works.
|
2022-12-30T01:08:52.805Z
|
117,933,162 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2172/771295",
"MAG": "1485734539",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GREEN",
"url": "https://digital.library.unt.edu/ark:/67531/metadc723310/m2/1/high_res_d/771295.pdf"
}
|
A brief summary of the 2000 meeting of the Division of Particles and Fields of the America Physical Society and a copy of the conference program are included in this final report.
|
2022-06-18T09:32:18.159Z
|
29,899,037 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CBMS.2013.6627779",
"MAG": "2162903974",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Medical devices are increasingly capable of interacting with each other by leveraging network connectivity and interoperability, promising a great benefit for patient safety and effectiveness of medical services. However, ad-hoc integration of medical devices through networking can significantly increase the complexity of the system and make the system more vulnerable to potential errors and safety hazards. In this paper, we address this problem and introduce an organ-centric compositional development approach. In our approach, medical devices are composed into semi-autonomous clusters according to organ-specific physiology in a network-fail-safe manner. Each organ-centric cluster captures common device interaction patterns of sensing and control to support human physiology. The library of these formally verified organ-centric architectural patterns enables rapid and safe composition of supervisory controllers, which are specialized for specific medical scenarios. Using airway-laser surgery as a case study of practical importance, we demonstrate the feasibility of our approach under Simulink's model-driven development framework.
|
2022-06-28T20:39:34.272Z
|
133,365,280 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.18356/b64f26a8-en-fr",
"MAG": "2562736765",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Agreement for the establishment of the global crop diversity trust. Rome, 4 october 2003 [united nations, treaty series, vol. 2366, i-42651.]
|
2022-07-01T05:05:39.407Z
|
88,856,365 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4315/0362-028X-59.11.1164",
"MAG": "2463571894",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The ability of Arcobacter butzleri to survive irradiation under vacuum in ground pork was determined and compared with that of Campylobacter jejuni . The D10 value for A. butzleri (0.27 kGy) was 1.4 × higher than that of C. jejuni (0.19 kGy). In addition, the D10 values for both organisms showed that an irradiation treatment of 1.5 kGy would yield a 5-log-unit reduction in the number of A. butzleri cells and a 7-log-unit reduction in the number of C. jejuni cells. This is sufficient to render meat products safe from these pathogens. These data indicate that A. butzleri is more tolerant to irradiation than C. jejuni .
|
2022-12-20T22:39:39.970Z
|
123,573,419 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1121/1.1973481",
"MAG": "2071171090",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://asa.scitation.org/doi/pdf/10.1121/1.1973481"
}
|
The ultrasonic absorption in a number of liquids whose molecular structure is a six‐membered ring has been measured over the frequency range 0.6–45 MHz at temperatures in the range −100 to +150°C. In piperidine and piperazine derivatives, a large relaxation with a low relaxation frequency is found at the higher temperatures of measurement. The activation energy of the relaxation indicates a barrier to inversion of the chair form of the ring of ∼10 kcal/mole. In cyclohexene and cyclohexanone derivatives, a different relaxation is found at the lower temperatures with a high relaxation frequency. Its molecular mechanism is believed to be the interconversion of chair and boat configurations of the ring, and these measurements represent, apparently, the only direct physical measurements of the elusive and important boat form in relatively simple molecules.
|
2022-01-27T09:06:44.932Z
|
157,960,763 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/003072705600100308",
"MAG": "2727784673",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
British Farming. J. A. S. Watson and J. A. More. Tenth edition, revised. Pp. 983, with line and half-tone illustrations. Oliver and Boyd Ltd., Edinburgh. 1956. 31s. 6d. net. Nearly every student of agriculture is liable to find that either "Fream" or "Watson and More" is required reading for examination purposes. It is a pleasure therefore, to review the tenth edition of the latter. The senior author (who now has a number of collaborators) has been successively Professor of Rural Economy at Oxford, agricultural attache in Washington and Director General of the advisory services. He is thus in a unique position to paint an overall picture of the farming industry in this country. British farming is indeed fortunate in having textbooks of this kind. There is, for example, nothing of similar calibre in the United States. It is, of course, impossible to cover the whole field in detail, but the introductions to subjects such as soil science or genetics are likely to whet the appetite of the student to look elsewhere for further information. The book is divided into four parts. The first gives a brief description of soil types, plant growth, manuring and cultivations. This is a good introduction and covers the ground very adequately. In dealing with implements, however, the pruning of material given in earlier editions might have been more drastic. The space given to illustrating horse-ploughs and cultivators might with advantage have been devoted to tractor-mounted implements. Most modern implements are mentioned, but the student might have difficulty in understanding their mechanism from a written description alone. In a later chapter, nine pages are given to a description of the threshing machine (which usually belongs to a contractor) and only one paragraph to the baler (which is more often owned by the farmer). There is also surprisingly little mention anywhereof one of the chief problems of the man starting in farming-the high capital cost of machinery and the economic considerations which should govern the choice of implements. The chapter on weed control is, however, an admirable summary of a new and rapidly developing field. The next section is well presented and surveys the cultivation, seed varieties and diseases of the principal crops. Occasionally one feels that undue space is given to obsolescent varieties-particularly of ceo reals, but this is not a subject on whichone BOOK REVIEWS
|
2022-02-08T23:58:48.722Z
|
115,050,037 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4028/www.scientific.net/AMM.847.529",
"MAG": "2482226388",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A new type of hybrid wood-bamboo shear wall was studied. Ply-bamboo is used as the sheathing panel for conventional two-by-four lightweight woodframe shear walls herein. Two different nails were adopted for the ease constructability and used for constructing the shear walls, as follows: gun-driven T shape nail and 6d common nail. Monotonic and cyclic test results of sheathing-frame connectors and corresponding full scare shear walls were also reported. The results obtained from the research reported in this paper indicated that ply-bamboo panels can be used as sheathings for light-weight timber shear walls.
|
2022-02-10T01:04:20.424Z
|
1,611,400 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ASSCC.2013.6691030",
"MAG": "2097290389",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A wireless power management and data telemetry circuit module for high compliance voltage electrical stimulation applications is presented in this paper. The system consists of rectifier, LDOs, DC-DC step-up charge pump and power monitoring circuit for closed loop wireless power management. The system also consists of a clock and data recovery (CDR) circuit and load shift keying (LSK) modulator for bidirectional data telemetry. The system operates at 13.56MHz. The wireless power management block receives AC power through an implantable coil and outputs three DC levels: 1V, 1.8V and 10V. The CDR circuit recovers clock and data from the 13.56MHz RF carrier through the same coil. The power efficiency of the wireless power management system is measured as 42% with 100μA current load connected on each supply output. The forward and backward data rate of the data telemetry achieves 61.5 kbps and 33.3 kbps, respectively. The system is implemented in 0.18μm CMOS process with 24V HV LDMOS option, occupying a core area of 1.8 mm × 1.8 mm.
|
2022-08-20T04:34:08.095Z
|
247,360,680 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.11406/rinketsu.63.104",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Variants of the t (8;21) (q22;q22) involving chromosome 8, 21, and other chromosomes account for about 3% of all t (8;21) (q22;q22) in patients with acute myeloid leukemia (AML). However, the prognosis of AML with variant t (8;21) remains unknown due to the scarcity of reported cases. Herein we report a case of AML with t (6;21;8) (p23;q22;q22). Fluorescence in situ hybridization confirmed a RUNX1-RUNX1T1 fusion signal on the derivative chromosome 8. This is the first report on a variant of t (8;21) involving the breakpoint 6p23. After induction chemotherapy, our patient achieved complete remission and has been stable for four years.
|
2022-03-11T07:17:15.283Z
|
46,074,323 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/imhj.21448",
"MAG": "1776326953",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The aim of this study was to investigate the mother-infant relationship in depressive, psychosocial, and cumulative-risk parenting by assessing prenatal and postnatal maternal representations and mother-infant interactions during feeding at 4 months of age. The sample consisted of 167 mother-infant pairs: 41 nonrisk women, 40 depressive-risk women, 40 psychosocial-risk women, and 46 cumulative-risk women. During pregnancy, the women were interviewed about psychosocial-risk variables. Maternal representations and depressive symptoms were evaluated during pregnancy and again when the infants were 3 and 4 months old, respectively. All mother-infant pairs were observed in 20-min video recordings during breast-feeding. Maternal Integrated/balanced representations were more frequent in the nonrisk group whereas the maternal Nonintegrated/ambivalent category was more represented in the cumulative-risk group during pregnancy and after the infant's birth. At 4 months, the cumulative-risk group of mothers and infants showed a lack of reciprocity, conflictual communicative exchanges, and higher food refusal behavior. Moreover, at 4 months, differences between the quality of mother-infant feeding interactions and the quality of prenatal and postnatal maternal representations emerged, showing less adequate maternal scaffolding in the Nonintegrated/ambivalent and Restricted/disengaged women. This study has rich implications for intervention to support the affective and communicative caregiving system and to prevent infant feeding problems and mother-infant relational disturbances in childhood.
|
2022-12-09T20:33:48.817Z
|
18,248,927 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1145/2911451.2911541",
"MAG": "2337426477",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Conventional Web search is predicated on returning results to users as quickly as possible. However, for some search tasks, users have reported a willingness to wait for the perfect set of results. In this work, we present the first study to analyze users' willingness to wait and their search success, when given a Web search system that embodies characteristics of slow search, where speed can be traded for an improvement in quality. We conducted a between-subjects user study involving tasks that required multiple queries to complete, providing a Web search system that gave users the option to additionally issue asynchronous queries for which results improve in relevance over time as users continued working. We analyze the resulting survey results and interaction log data to investigate how users spent their time while waiting, and how behavior and search outcomes changes when users are given the option of using a system with asynchronous slow search capabilities. We find that when given a slow search system, users are able to perceive the improvement in quality over time, and find tasks to be easier compared to a baseline conventional Web search system. Additionally, we find that users continue to issue their own queries and examine additional documents while the slow search queries are processed in the background, and use the slow search feature more effectively as they gain exposure to its behavior across tasks. Our study significantly advances our understanding of the benefits and tradeoffs involved in providing slow search scenarios for Web search.
|
2022-12-17T16:49:06.435Z
|
8,223,964 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/HUMREP/DEH716",
"MAG": "2139115847",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
BACKGROUND
The aim of this study was to determine the relationship between the proportion of motile sperm with actin exposed on the surface of the head and sperm function.
METHODS
Semen samples were obtained from normozoospermic men and sperm function tests were performed. Motile sperm selected by swim-up were incubated with actin monoclonal antibody (A-mAb, 1:100) for 2 h, then anti-mouse IgG Dynabeads were used to detect sperm-bound A-mAb. Sperm capacitation was increased by phorbol myristate acetate (PMA) and decreased by bicarbonate-free medium.
RESULTS
The proportion of sperm with exposed actin increased with time for up to 2 h incubation. Bicarbonate-free medium significantly decreased the proportion of sperm with exposed actin. PMA significantly enhanced this phenomenon. Sperm bound to zona pellucida (ZP) had a significantly higher proportion with exposed actin than did sperm remaining in medium. Of the 79 samples studied, an average of 9.4% (range 1-27%) of motile sperm had exposed actin after 2 h incubation and this was significantly correlated with sperm normal morphology and ZP binding.
CONCLUSION
Exposure of actin on the surface of the sperm head during in vitro culture may be related to membrane modification during sperm capacitation and hence may be a useful marker for this subpopulation of sperm.
|
2022-12-17T22:50:59.804Z
|
145,197,337 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S1744552311000395",
"MAG": "2149554426",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract This article presents an empirical study of Jewish and Muslim women who go through divorce in Canada, drawing on a ‘left law and economics’ methodology. Religious law and family law have long been considered outside the market and, as a result, are more rarely accounted for in the law and economics literature. According to dominant narratives, religious family law is experienced by women either as an exceptional form of oppression or as a form of spiritual religious identity. In this article, I apply a ‘left law and economics’ approach to deconstruct these notions. On the basis of my socio-legal fieldwork with Jewish and Muslim women in three Canadian cities, I identify the background formal and informal legal rules, social norms and distributional practices that help produce asymmetric bargaining locations for women. I employ the economic language of costs/benefits to illustrate the ways in which religious parties bargain strategically upon divorce, although these market claims are surprisingly underrecognised by the legal system. Such empirical knowledge helps disenchant the idea that religious law is systematically used as punishing forces that make women worse off economically or morally inferior. It also allows for a distributive analysis which reveals how husbands and wives negotiate economic resources, desires and day-to-day decisions in all kinds of fair and unfair ways, flying in the face of conventional narratives surrounding women and religion.
|
2022-12-18T08:52:38.378Z
|
15,470,525 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1155/2013/742859",
"MAG": "2066446736",
"PubMedCentral": "3770014"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://downloads.hindawi.com/journals/bmri/2013/742859.pdf"
}
|
An extensive range of pigments including phycobiliproteins are present in algae. C-phycocyanin (C-PC), a phycobiliprotein, is one of the key pigments of Spirulina, a microalgae used in many countries as a dietary supplement. Algal pigments have massive commercial value as natural colorants in nutraceutical, cosmetics, and pharmaceutical industries, besides their health benefits. At present, increasing awareness of harmful effects of synthetic compounds and inclination of community towards the usage of natural products have led to the exploitation of microalgae as a source of natural pigments/colors. This review describes recent findings about the sources and production of C-PC, with emphasis on specific techniques for extraction and purification, along with potential industrial applications in diagnostics, foods, cosmetics, and pharmaceutical industries.
|
2023-01-01T17:26:34.190Z
|
144,382,902 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1353/RAH.0.0047",
"MAG": "2054435715",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Should governments deal with their foreign adversaries by pursuing high-level talks or by refusing to negotiate at all? The question, an old one for political leaders and diplomats, has seldom been so explicitly debated as it was during the U.S. presidential campaign in 2008. Democratic nominee Barack Obama declared himself willing to meet face-to-face with the leaders of hostile nations, notably Iranian President Mahmoud Ahmadinejad. As long as American leaders practiced "aggressive, principled diplomacy" with a "clear-eyed understanding of our interests," Obama stated, there was little to fear. Republican John McCain, eager to tar his rival as dangerously soft on national security, would have none of it, contending there was no point in talking to extremists. McCain insisted that a summit with Ahmadinejad would yield only "an earful of anti-Semitic rants and a worldwide audience for a man who denies one
|
2022-02-09T06:59:48.492Z
|
88,380,945 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2307/1446099",
"MAG": "2325266441",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Myxine mcmillanae is described from 43 specimens collected from Puerto Rico and the United States Virgin Islands at depths of 700 to approx. 1500 m. It is a six-gilled, white-headed species with a two-cusp multicusp in each row. It differs from all described white-headed species in numbers of gills and cusps on multicusps. Specimens of M. ios from Ireland bear a striking resemblance to M. mcmillanae in coloration but differ in having seven gill pouches.
|
2022-02-10T21:35:59.568Z
|
250,989,692 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/jfb.15175",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The reproductive behavior of the Andean Catfish Astroblepus ubidiai was observed directly and with an underwater camera in a spring located next to Lago San Pablo in the province of Imbabura, Ecuador in late 2015 and early 2016. Five mating attempts were observed, four of which were videotaped, and two of which resulted in complete copulation. During copulation, the male grabs the female from the top of the head with its buccal disc and pelvic fins, and from this position, bends its body forming a "C" to reach the genital pore of the female and introduce its copulatory organ. Once copulation is complete, the female swims away rapidly. Details of the copulation are described here through illustrations. This article is protected by copyright. All rights reserved.
|
2022-07-31T12:42:46.321Z
|
135,509,503 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4028/www.scientific.net/AMR.750-752.655",
"MAG": "1980813775",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In order to settle the environmental pollution and improve the excellent rate of products, ZL109 piston alloy modified by Al9Fe3P master alloy was prepared in factory. The microstructures and mechanical properties of ZL109 piston alloy were invested respectively. The technological parameters and modifying effect of using Al9Fe3P alloy were researched too. Experiments show that high quality of ZL109 pistons can be produced by adding 0.4~0. 5wt% Al9Fe3P master alloy at 760-770°C.The maxim and average grain size of primary Si decrease largely, less than 66μm and 40μm respectively, and the mechanical properties were improved accordingly. It was proved that Al-Fe-P master alloys have advantages such as no pollution, no reaction slag, shorter modifying time and saving energy, which would reduce the total cost of piston products. So Al-Fe-P master alloy is a promising modifier to refine ZL109 piston alloys.
|
2022-09-08T10:12:53.244Z
|
159,038,491 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/mus.26520",
"MAG": "2945201173",
"PubMedCentral": null
},
"license": "CCBYNC",
"status": "GREEN",
"url": "https://vbn.aau.dk/ws/files/466017258/Assessing_the_modulation_of_cutaneous_sensory_fiber_excitability_using_a_fast.pdf"
}
|
Topical application of lidocaine‐and‐prilocaine (LP) cream attenuates the functionality of small cutaneous nerve fibers. The aim of this human study was to measure the underlying excitability modulation of small cutaneous nerve fibers using a novel and fast perception threshold tracking (PTT) technique.
|
2022-12-16T01:01:51.574Z
|
29,479,483 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/(SICI)1099-1271(199807/08)13:4<185::AID-BIO486>3.0.CO;2-U",
"MAG": "2038729522",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We have recently proposed that the expression of V. fischeri right lux operon is controlled by two promoters; the first one located upstream of the luxl gene, while the second one seems to be located upstream of the luxC gene. The transcription from both promoters is negatively controlled by H-NS protein. Escherichia coli MC4100 rpoS hns mutant that carried the V. fischeri lux system with a deletion in either the luxl or luxR gene showed a constitutive mode and more than 10,000-fold higher luminescence than the control cells. The present study shows that neither luxR nor luxl are required for the transcription of the luxCDABE genes in an H-NS deficient strain of E. coli. The MC4100 rpoS hns mutant harbouring the luxCDABE-carrying plasmid showed constitutive mode and 70,000-fold higher luminescence than the wild-type cells. The question whether both the left and the right operons of V. fischeri lux system are controlled by H-NS was addressed with the aid of plasmids harbouring the lacZ gene fused with luxR or luxl. In MC4100 hns rpoS background, luxR and luxl genes were very early and actively transcribed, as judged by the strong beta-galactosidase activity that was developed at early stage of growth. The beta-galactosidase activity in the wild-type cells was 20-40 times lower and occurred mainly during the second half of the growth cycle. It thus appears that H-NS inhibits the transcription of three promoters of the lux system of V. fischeri; the left operon that codes for LuxR protein and two promoters located upstream and downstream to luxl gene.
|
2022-12-19T06:36:56.385Z
|
249,785,621 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1096/fasebj.31.1_supplement.950.11",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The proposed research explores the regulation of glucose metabolism in Saccharomyces cerevisiae. Specifically, the focus is on how the loss of endocytic function results in aberrant glucose homeostasis through the deregulation of glucose transporter localization/function. By combining methods of yeast genetics, molecular biology, and cell biology, novel features regulating transporter function and localization will be studied to uncover mechanisms for maintaining glucose homeostasis. Data show that the BAR domain protein Rvs161 is required for proper transporter localization and function.1 Recent reviews describes BAR domain containing proteins as curvature inducing/stabilizing proteins essential for affecting a wide variety of membrane remodeling processes, including endocytosis.2 Endocytosis and degradation of transporters is critically important in maintaining glucose homeostasis in yeast as well as mammals. Saccharomyces cerevisiae is a well‐established model organism for the study of endocytosis.3 Additionally, yeast share similar components of glucose signaling and glucose transporter pathways with mammalian counterparts making yeast a useful model system for studies of glucose transporter biology.4, 5 Yeast strains lacking the RVS161 gene fail to grow under conditions of glucose limitation and harbor endocytosis defects. Our data indicate that overexpression of specific glucose transporters can suppress this defect. Additionally, our data suggests that glucose transporter interactions are required for proper transporter function and that Rvs161p is required for proper transporter localization and function.
|
2022-12-19T23:42:29.466Z
|
53,470,422 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1046/J.1365-313X.1994.5060773.X",
"MAG": "2126164361",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Summary
Tobacco cells adapted to grow in high concentrations of NaCl exhibit a drastically altered growth physiology that results in cells whose fully expanded volume is only one-fifth to one-eighth those of unadapted cells. Comparison between NaCl-adapted and unadapted tobacco cells provides an opportunity to evaluate current concepts of the structural and mechanical determinants of cell wall expansion. Both biochemical studies of pectic polymers and the ultrastructural localization of pectic epitopes at three specific phases of cell culture, maximal cell division, maximal elongation, and stationary phase are reported here.
One-half of the galactosyluronic acid units in wall polymers of NaCl-adapted cells are esterified throughout the culture period, while wall polymers of unadapted cells show a rise in esterified polygalacturonic acid from 50 to 80% during elongation and then a decrease to 70% at stationary phase. Methyl esters account for only a proportion of the total esterified polygalacturonic acid at any stage in both unadapted and NaCl-adapted cell walls. Using monoclonal antibodies, we show differences in the localization of relatively methyl-esterified and unesterified pectic epitopes at different stages of growth and corroborate the chemical determinations. Fourier transform infrared (FTIR) microspectroscopy of representative walls of both NaCl-adapted and unadapted cells confirms, at the single cell wall level, that results obtained from chemical analysis of bulk samples are applicable to the entire cell population.
FTIR microspectroscopy also reveals an increase in wall protein in the walls of adapted cells. Images obtained by the fast-freeze, deep-etch, rotary-shadowed replica technique show clearly different cell wall architectures in NaCl-adapted compared with unadapted cells; walls of elongating unadapted cells contain long, thin fibres that show a net orientation with respect to the long axis of the cell, whereas walls of adapted cells have thicker, flatter bundles of fibres with no clear net orientation. Polarized FTIR microspectroscopy indicates that, in unadapted tobacco cells during elongation, pectin molecules may be oriented within the wall in a similar manner to cellulose. Possible ways in which pectin structure and conformation may affect the behaviour of the cellulose-xyloglucan network are discussed.
|
2022-12-22T16:45:26.733Z
|
91,186,633 |
{
"externalids": {
"ACL": null,
"ArXiv": "1812.03196",
"DOI": "10.1103/PhysRevE.99.022140",
"MAG": "2903619453",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We introduce "bond-counting" potentials, which provide an elementary description of covalent bonding. These simplistic potentials are intended for studies of the mechanisms behind a variety of phase transitions in elemental melts, including the liquid-liquid phase transitions (LLPTs) in phosphorus and bismuth. As a first study employing such potentials, an analytic solution of a one-dimensional model system is presented, including its thermodynamic properties and its structure factor. In the simplest case, the chemical valency of each atom is 1, and either single atoms or diatomic molecules are present. At low temperatures and moderate pressures, the system consists almost exclusively of molecules, and single atoms act as topological defects. A slightly more complicated case involves a valency of 2, with either single or double bonding. This system exhibits a first-order LLPT from a molecular to a polymeric phase as in phosphorus. In this case, the one-dimensional model system exhibits phase separation for finite-sized systems at low temperatures. A variant of this system also exhibits a nonequilibrium phase transformation upon heating the molecular condensed phase, qualitatively similar to boiling in white phosphorus.
|
2022-12-22T12:17:36.203Z
|
174,799,187 |
{
"externalids": {
"ACL": null,
"ArXiv": "1906.01645",
"DOI": "10.1364/AOP.361502",
"MAG": "2948602808",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Quantum cryptography is arguably the fastest growing area in quantum information science. Novel theoretical protocols are designed on a regular basis, security proofs are constantly improving, and experiments are gradually moving from proof-of-principle lab demonstrations to in-field implementations and technological prototypes. In this review, we provide both a general introduction and a state of the art description of the recent advances in the field, both theoretically and experimentally. We start by reviewing protocols of quantum key distribution based on discrete variable systems. Next we consider aspects of device independence, satellite challenges, and high rate protocols based on continuous variable systems. We will then discuss the ultimate limits of point-to-point private communications and how quantum repeaters and networks may overcome these restrictions. Finally, we will discuss some aspects of quantum cryptography beyond standard quantum key distribution, including quantum data locking and quantum digital signatures.
|
2022-12-30T18:40:42.754Z
|
151,813,704 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2139/SSRN.2926939",
"MAG": "2610508052",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Spanish Abstract: Las conceptualizaciones tradicionales sobre proteccion social han sido criticadas por diversos aspectos conceptuales, y mas recientemente han sido senaladas de no tener en cuenta las necesidades del ciclo de vida, en particular de ninos y adolescentes. El objetivo de este articulo es revisar las conceptualizaciones tradicionales y presentar una propuesta nueva sobre que debe ser un Sistema de Proteccion Social Integral, sensible a este grupo etario, para Colombia. Para ello se proponen tres componentes que deberian constituir el sistema: i) Seguridad social integral universal ii) Asistencia social focalizada en los pobres y iii) Promocion del capital humano y prevencion de la exclusion social de caracter universal, siendo este ultimo el mas importante para la proteccion de ninos y adolescentes.
English Abstract: Traditional approaches of social protection have been largely criticized for conceptual reasons. More recently it has been pointed out that they don’t take into account the inherent needs of the life cycle, in particular those of children and adolescents. The aim of this paper is to review the traditional approaches of social protection and present a new proposal on what should be an Integrated Social Protection System sensitive to this age group for Colombia. This article presents the three components that should found the system: i) Universal Integral Social Security, ii) Social Assistance focused on the poor, iii) Universal Promotion of Human Capital and Prevention of Social Exclusion, the last one being the most important for protection of children and adolescents
|
2022-02-09T03:11:26.273Z
|
26,223,868 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/TNS.2004.839106",
"MAG": "2102031546",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The first demonstration of through-wafer two-photon absorption (TPA) single-event effects (SEEs) testing is presented. We interrogate the single-event transient (SET) response of several different nodes of the LM124 operational amplifier via TPA carrier injection through both the front and back (substrate) chip surfaces. The results reveal that the SETs and sensitivities produced in several different nodes by front-side and back-side irradiation are effectively identical, confirming the validity of this approach for SEE studies.
|
2022-12-29T20:18:41.420Z
|
53,102,145 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/1536012118801223",
"MAG": "2899390133",
"PubMedCentral": "6207972"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://journals.sagepub.com/doi/pdf/10.1177/1536012118801223"
}
|
Targeted therapies hold great promise for cancer treatment and may exhibit even greater efficacy when combined with patient selection tools. The clinical impact of identifying likely responders includes reducing the number of unnecessary and ineffective therapies as well as more accurately determining drug effects. Positron emission tomography (PET) imaging using zirconium-89 radiolabeled monoclonal antibodies (mAbs), also referred to as zirconium-89 (89Zr)-immuno-PET, provides a potential biomarker to measure target expression and verify optimal delivery of targeted agents to tumors. Antibody–drug conjugates (ADCs) combine the high affinity and specificity of mAbs with the potency of cytotoxic drugs to target tumor-expressing antigen and destroy cancer cells. Thus, 89Zr-immuno-PET of whole-body biodistribution, pharmacokinetics, and tumor targeting of antibodies and ADCs to predict toxicity and efficacy could help guide individualized treatment. Here, we review how 89Zr-immuno-PET is being used as a companion diagnostic with the development of ADCs. Furthermore, we discuss how 89Zr-immuno-PET may be utilized in future clinical trials as an adjunct tool with novel ADCs to select cancer patients who have the greatest potential to benefit from treatment and improve ADC dosing regimens.
|
2022-12-30T20:31:25.891Z
|
187,640,016 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.26450/JSHSR.23",
"MAG": "2741546920",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
1982 Anayasa‟si ile ulkemizin hukumet sistemi olarak parlamenter sistem kabul edilmis fakat yasanan tarihi olaylar ve ayni zamanda sosyo-ekonomik yapida meydana gelen degisim ve gelismeler parlamenter sistemin degismesi ve yeni hukumet sistemlerinin tartisilmasi gerektigine yonelik dusuncelerin de ortaya cikmasina neden olmustur. Ozellikle anayasada 2007 yilinda yapilan degisik ile mevcut hukumet sisteminin hukumet sistemleri icerisindeki yerinin tespitine yonelik tartismalar da hiz kazanmistir. Bu baglamda alternatif olarak sunulan yari baskanlik sistemi, ulkemiz siyasi gecmisinde cok sayida tartismaya konu olmustur. Nitekim bu sistem varligi karsisinda, yurutme organinin istikrarsizligina yonelik elestiriler soz konusu olabildigi gibi ayni zamanda tam bir gelismis ulke profili yaratacagina yonelik gorusler de bulunmaktadir
|
2022-02-08T10:36:24.360Z
|
137,645,309 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1504/IJAT.2007.015379",
"MAG": "1968804243",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
For micro/nano positioning systems using piezoelectric actuators for precision grinding process control, sinusoidal command signals will be used and will give additional problems in comparison with the commonly used step signals due to the hysteresis effect, which require good modelling of the effect. To avoid discontinuity in obtaining the values of the piezoelectric constant, a method of direct mapping with polynomial fit has been proposed. Compared with the single polynomial approach, the model obtained was able to reduce the modelling error by 6.5%. To further reduce the modelling error, a new method using direct mapping and numerical analysis is proposed while discontinuity is avoided. Theoretical and experimental studies are conducted and comparative studies are made. Compared with the single polynomial approach, it is able to reduce the modelling error to 7.3%, which is 45.5% lower. Compared with the direct mapping with polynomial approach, the proposed method is able to reduce the modelling error by 41.7%. For a typically fast piezoelectric micro/nano positioning system, hysteresis distortion is more significant towards modelling error than dynamic distortion. The proposed new approach should be useful in precision grinding process control.
|
2022-02-09T10:30:37Z
|
86,811,591 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.23917/jk.v11i1.7001",
"MAG": "2917902401",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://doi.org/10.23917/jk.v11i1.7001"
}
|
ASI Eksklusif mempunyai manfaat bagi perkembangan dan pertumbuhan bayi. Selain itu juga bermanfaat bagi perkembangan mental dan emosional anak. Kandungan seng pada ASI diperlukan untuk tumbuh kembang seperti ketrampilan motorik kasar, motorik halus, kemampuan bicara dan bahasa serta kemampuan sosialisasi dan kemandirian. Penelitian dilakukan di Puskesmas Mantingan dengan pertimbangan pencapaian ASI Eksklusif di Puskesmas Mantingan tahun 2015 masih rendah yaitu sebesar 64,7 %. Tujuan penelitian adalah untuk mengetahui perbedaan perkembangan motorik pada balita usia 7 – 24 bulan yang ASI Eksklusif dan non ASI Eksklusif di Puskesmas Mantingan. Penelitian ini menggunakan desain cross-sectional. Jumlah responden penelitian yaitu 48 responden ASI Eksklusif dan 48 non ASI Eksklusif dengan teknik pengambilan sampel Simple Random Sampling. Data ASI Eksklusif diambil dengan menggunakan kuesioner, perkembangan motorik diperoleh menggunakan form KPSP yang dilakukan oleh bidan yang telah mengikuti pelatihan DDTK. Uji kenormalan data menggunakan Kolmogorov Smirnov Test dan uji perbedaan menggunakan uji Mann-Whitney. Hasil penelitian menunjukkan bahwa perkembangan motorik sesuai harapan 51,8 % pada balitas ASI Eksklusif dan 48,2 % pada balita non ASI Eksklusif. Perkembangan motorik meragukan 36,4 % pada balita ASI Eksklusif dan 63,6 % pada balita non ASI Eksklusif. Kesimpulan dari penelitian ini adalah ada perbedaan perkembangan motorik balita usia 7 – 24 bulan yang ASI Eksklusif dan non ASI Eksklusif di Puskesmas Mantingan (p = 0,039).
|
2022-11-06T15:14:16.178Z
|
100,645,182 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/ACSCATAL.5B01445",
"MAG": "2280607550",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The mechanism of iron-catalyzed carbon–carbon cross-coupling reactions between Grignard reagents and alkyl halides has been investigated using well-defined N-heterocyclic carbene (NHC) compounds. The iron(II) precatalyst, [Fe2Cl2(μ-Cl)2(IPr)2], was employed in several C–C cross coupling reactions exhibiting the ability to efficiently couple primary and secondary alkyl halides with several aryl and alkyl Grignard reagents. For selected substrates, a 2 mol % catalyst loading (4 mol % Fe) afforded conversions of >99% and were achieved with <8% homocoupling of the electrophile. The mechanism of the coupling reaction was studied by means of radical clock, radical trap, and single-turnover experiments, which support a radical-based cycle involving an Fe(II/III) redox couple. The implications of this mechanism on the efficacy of iron-NHC-catalyzed cross-coupling reactions are discussed.
|
2022-12-20T04:12:32.750Z
|
74,525,970 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1161/hyp.60.suppl_1.a492",
"MAG": "2257959882",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Aim:
To evaluate the effect of experimental hyperleptinemia for 7 days and the participation of the Renin-Angiotensin II System (RAS) on renal function and morphology.
Methods:
40-days male Wistar rats were divided into 4 groups (n = 5 - 6 per group): sham (
Sh
), Leptin (
Lep
; s.c. infusion 0.5mg/kg/day, osmotic pump, Alzet), Losartan (
Los
; s.c. 10 mg/kg/day), Leptin plus Losartan (
LL
). Systolic blood pressure (SBP) was measured by tail-cuff method. On 8
th
day, rats were anesthetized and prepared to renal clearance experiments. Renal plasmatic flow (RPF) and glomerular filtration rate (GFR) were determined by p-Aminohippuric acid sodium and inulin clearance. Urinary NH
4
+
, pH, Na
+
, K
+
and osmolality were analyzed. Renal tissue was submitted to histological studies.
Results:
7-days Leptin treatment increased SBP (
Sh
: 105,8 ± 0,7
vs
Lep
: 118,0 ± 1,5 mmHg; *p<0.0001) and
LL
group reversed this parameter (
LL
: 103,4 ± 0,7 mmHg; *p<0.0001). Our preliminary results showed that Leptin and/or Losartan treatment does not affect renal hemodynamic (RPF -
Sh
: 20,48 ± 0,77
vs
Lep
: 15,79 ± 1,02
vs
Los
: 17,96 ± 2,21
vs
LL
: 18,99 ± 1,54 ml/min/kg and GFR -
Sh
: 7,94 ± 0,46
vs
Lep
: 9,19 ± 0,59
vs
Los
: 7,46 ± 0,60
vs
LL
: 6,97 ± 0,52 ml/min/kg). However, filtration fraction increased significantly in
Lep
group (
Sh
: 40,40 ± 1,72
vs
Lep
: 59,79 ± 2,46 %*; *p < 0.0001) and was corrected by Losartan (
LL
34,42 ± 3,06 %
#
;
#
p< 0.0001). Urinary flux increased in
Lep
rats and was also corrected by Losartan (
Sh
: 0,18 ± 0,01
vs
Lep
: 0,25 ± 0,02; *p<0.001
vs
LL
: 0,18 ± 0,008
#
;
#
p< 0.0001 ml/min/kg). Na
+
excretion, which had an 337% increase in
Lep
group, was normalized in
LL
. Urinary excretion of NH
4
+
and K
+
and urinary osmolality was not different between the studied groups. All parameters of
Los
group were not statistically different from
Sh
rats.
Lep
rats showed an increase in total glomerular area, which was also corrected in
LL
rats (
Sh
: 6708 ± 62
vs
Lep
: 7796 ± 130
vs
Los
: 6779 ± 23
vs
LL
6822 ± 20 μm
2
).
Discussion:
Lep
rats showed higher SBP, but not hypertension. Although there were no significant changes in renal hemodynamic, Leptin treatment caused glomerular hypertrophy. As many parameters were corrected by co-treatment with Losartan, it seems that RAS has a critical role in hyperleptinemic induced renal changes.
|
2022-12-20T07:24:39.838Z
|
138,981,586 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1744-7402.2006.02059.X",
"MAG": "2144517782",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Reactive hot pressing is discussed as a processing method to form ceramic-based materials. Fundamental aspects of thermodynamics such as favorable Gibbs'-free energy changes, phase equilibria, and adiabatic temperature are presented as criteria for determining whether the desired reactions can be used to form dense materials. Two case studies are presented as examples to describe control of microstructure and properties. The fabrication of Al 2 O 3 -Nb and ZrB 2 are discussed with respect to the three thermodynamic criteria as well as the microstructure and properties of the materials that are produced.
|
2022-12-21T10:32:46.128Z
|
235,255,190 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1161/JAHA.120.019521",
"MAG": null,
"PubMedCentral": "8477875"
},
"license": null,
"status": null,
"url": null
}
|
Background The opening of mitochondrial permeability transition pore and inflammation cooperatively progress myocardial ischemia‐reperfusion (IR) injury, which hampers therapeutic effects of primary reperfusion therapy for acute myocardial infarction. We examined the therapeutic effects of nanoparticle‐mediated medicine that simultaneously targets mitochondrial permeability transition pore and inflammation during IR injury. Methods and Results We used mice lacking cyclophilin D (CypD, a key molecule for mitochondrial permeability transition pore opening) and C‐C chemokine receptor 2 and found that CypD contributes to the progression of myocardial IR injury at early time point (30–45 minutes) after reperfusion, whereas C‐C chemokine receptor 2 contributes to IR injury at later time point (45–60 minutes) after reperfusion. Double deficiency of CypD and C‐C chemokine receptor 2 enhanced cardioprotection compared with single deficiency regardless of the durations of ischemia. Deletion of C‐C chemokine receptor 2, but not deletion of CypD, decreased the recruitment of Ly‐6Chigh monocytes after myocardial IR injury. In CypD‐knockout mice, administration of interleukin‐1β blocking antibody reduced the recruitment of these monocytes. Combined administration of polymeric nanoparticles composed of poly‐lactic/glycolic acid and encapsulating nanoparticles containing cyclosporine A or pitavastatin, which inhibit mitochondrial permeability transition pore opening and monocyte‐mediated inflammation, respectively, augmented the cardioprotection as compared with single administration of nanoparticles containing cyclosporine A or pitavastatin after myocardial IR injury. Conclusions Nanoparticle‐mediated simultaneous targeting of mitochondrial injury and inflammation could be a novel therapeutic strategy for the treatment of myocardial IR injury.
|
2022-12-22T05:28:32.561Z
|
121,087,272 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1063/1.1665557",
"MAG": "2061956498",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A new, and computationally simple, method is given for obtaining the characters of all the inequivalent irreducible vector representations of a finite group. The method was applied to determine the characters of the irreducible vector and ray representations of the four‐dimensional cubic crystal point groups: group 47 and group 45. These groups are of order 384 and 1152, respectively, and contain the cubic point group in three dimensions Oh[3] as a subgroup. Tables are given of the irreducible representations of Oh subduced by the irreducible representations of group 47 and group 45. These tables may be useful in testing the conjecture that accidental degeneracy in problems in solid state physics in three dimensions reflects a higher symmetry in four dimensions.
|
2022-09-15T05:38:12.688Z
|
244,310,878 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5149/northcarolina/9781469660172.003.0020",
"MAG": "3204387936",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The failed attacks of May 19 and 22 produced many opportunities for participants to garner honors or deserve infamy, and those incidents either strengthened the rest of their lives or haunted them forever. A number of Federals failed the test of combat and shirked their duty, but the military justice system was weak and porous at best. While some of these acts of combat failure were officially reported, little was done by the system to punish the men. Officers were allowed to resign and the process of dealing with enlisted men was rarely called into use. It was easier to allow the individual to reflect and improve in his future conduct. Sgt. Joseph E. Griffith became a national hero because of his exploit at Railroad Redoubt. In fact, Griffith eventually won an appointment to West Point where he graduated and became an officer in the U. S. Army. Fourteen-year-old Orion P. Howe of the 55th Illinois became famous for telling William T. Sherman of the need for more cartridges as he returned from the failed attack of May 19 with a slight wound. Many members of the Forlorn Hope were awarded with Congressional Medals of Honor after the war.
|
2022-01-24T20:57:41.923Z
|
234,286,970 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.31782/IJCRR.2021.13620",
"MAG": "3136784205",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Introduction: Herpes zoster commonly known as shingle’s caused by the varicella-zoster virus (VZV). Current studies have shown that exosomes play a significant role in the pathogenesis as well as the spread of herpes. Combination therapy has shown pain reduction, reduction in burning and arrest the progression of the disease. This approach is cost-efficient and simple to implement. Pittaj visarga may be linked with herpes in Ayurveda. The treatment principles are Raktmokshan (~Bloodletting) and Pradeha (Local application of medicines). Case presentation: A 28-year-old male presented in OPD of Kayachikitsa at Datta Meghe Ayurved Medical College Hospital and Research Centre. We treated his Herpes zoster on the basic principles of management of Vata-Pittaj Visarpa. Results: Rapid decrease in pain severity was observed after 3 days of Combination Therapy according to the Zoster Specific Brief Pain Inventory (ZBPI) Questionnaire. Conclusion: Repeated application of Ayurvedic Formulation Lepa along with internal medications gave complete relief. Adaptive trials are necessary to discover further practical applicability of Ayurveda and modern treatment together. Future research on the effect of combination therapy on exosomes is necessary.
|
2022-02-07T21:40:26.561Z
|
14,540,547 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/IAS.2011.6074393",
"MAG": "2071990138",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A typical mining facility uses off-road mining trucks to haul materials, such as coal, ore, and overburden from the pit to a stockpile where the material can be stored or processed. A conventional haul truck operates with diesel engine, adding considerable fuel expenses to the entire mining operation. The haul trucks are required to have fast speed especially for uphill condition with large haulage capacity in order to satisfy the productivity requirement. The main objective of designing a haul truck is to reduce the cost per ton of hauled material. Generally, this can be achieved by improving the system efficiency, reducing the maintenance, and making larger trucks. The electric haul trucks have these advantages due to elimination of the mechanical conversion. The efficiency can be further improved by using overhead trolley line feeding electric power to the truck as much as possible. By this way, the operation time of diesel engine is reduced and the corresponding maintenance is significantly saved. One of the major concerns of using trolley system is the availability of the trolley line, which affects the productivity directly since one or more trucks rely on the trolley line. Hence it is extremely important that the power system with the right short circuit capability be designed. This paper presents the simulation results for the short circuit studies for different conditions, which cover the maximum and the short circuit currents. The results are expected to give good reference on the selection of power system network parameters.
|
2022-07-29T06:47:02.005Z
|
145,321,895 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.19030/CIER.V3I3.180",
"MAG": "2096125614",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The purpose of this study was to investigate if there is a relationship between the genders of teachers when it comes to fathers’ involvement in their children’s schooling in elementary classrooms. We attempted to answer the following questions: 1) Are the fathers less/more involved when the teacher is female? 2) Are the fathers less/more involved when the teacher is male? 3) Is there a correlation between the gender of the teacher and fathers’ involvement?
|
2022-08-31T15:12:38.728Z
|
572,902 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICIEA.2006.257321",
"MAG": "2109176910",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Many electronic drivers for the induction motor control are based on sensorless technologies. The proposal of this work is to present an efficient estimator of torque and speed, from transient to steady state, using artificial neural networks. The method proposed is based on off-line training considering different types of load and wide range of voltage applied to the induction motor. The inputs of the network are the RMS voltage and current of the induction motor and the control processing effort is reduced to simple matrix solving after the neural network is trained. Simulation results are also presented to validate the proposed approach
|
2022-09-07T09:03:56.603Z
|
53,627,656 |
{
"externalids": {
"ACL": null,
"ArXiv": "1810.04849",
"DOI": "10.1615/INT.J.UNCERTAINTYQUANTIFICATION.2019029046",
"MAG": "2962782894",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this work, we consider a non-standard preconditioning strategy for the numerical approximation of the classical elliptic equations with log-normal random coefficients. In \cite{Wan_model}, a Wick-type elliptic model was proposed by modeling the random flux through the Wick product. Due to the lower-triangular structure of the uncertainty propagator, this model can be approximated efficiently using the Wiener chaos expansion in the probability space. Such a Wick-type model provides, in general, a second-order approximation of the classical one in terms of the standard deviation of the underlying Gaussian process. Furthermore, when the correlation length of the underlying Gaussian process goes to infinity, the Wick-type model yields the same solution as the classical one. These observations imply that the Wick-type elliptic equation can provide an effective preconditioner for the classical random elliptic equation under appropriate conditions. We use the Wick-type elliptic model to accelerate the Monte Carlo method and the stochastic Galerkin finite element method. Numerical results are presented and discussed.
|
2022-09-08T04:36:05.474Z
|
248,127,893 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1159/000524137",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Introduction: Molecular targeted therapies have been established for various diseases, including cancers, and there is an increasing need for molecular testing on cytology specimens. The aim of this study was to determine the optimal preservation methods of liquid-based cytology (LBC) materials for molecular testing. Methods: Cytological samples from 35 surgical resected non-small cell lung carcinoma specimens were obtained between June 2016 and June 2021. The samples were fixed in CytoRich™ red Preservative and stored at 4°C. One week later, three tubes were prepared from each specimen sample and divided into the following groups: the SurePath™ group (continued storage at 4°C), Frozen (Fr) group (stored at −80°C after centrifugation), and LBC-Cell Block (LBC-CB) group (generation of paraffin-embedded CB and storage at 4°C). Samples from 5 patients were used for the time course analysis, and we performed evaluations on these samples at 1, 3, 6, 12, 24, and 36 months. The concentrations and purities of extracted DNA and RNA were measured. The double-stranded DNA (dsDNA) and RNA concentrations were also measured by a fluorometer. The DNA and RNA integrities were quantified by the DNA and RNA integrity number. Results: Evaluation of samples was performed at baseline and the six timepoints. In the LBC-CB group, DNA and dsDNA concentrations were higher rather than those in the other groups. The RNA concentration of the LBC-CB group was relatively high compared with those of the other groups at the 36-month timepoint. The Fr group maintained higher DNA quality compared with the other groups over 3 years. The LBC-CB group maintained a higher RNA quality than the other groups until 24 months. Conclusion: LBC-CB preparation is an effective method to maintain DNA/RNA quality and quantity in long-duration preservation for eventual molecular testing. Therefore, LBC-CB may have applications on preanalytical stage for molecular genomic testing such as next-generation sequencing.
|
2022-09-08T22:11:05.572Z
|
236,823,088 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.7833/9-0-1971",
"MAG": "3112781691",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://scriptura.journals.ac.za/pub/article/download/1971/1767"
}
|
Something is missing in contextual biblical hermeneutics in South Africa. The voice(s) of ‘the people’ or what I have called ‘the ordinary reader’ is missing. However, the influence of reader-response criticism in biblical studies, the commitment to an option for the poor and oppressed in liberation hermeneutics, and the consensus in post-modernism that here is no epistemologically privileged position, variously remind us of the voice of the ordinary reader (West 1991a). Fortunately, there has been some recognition of the need to hear the ordinary reader in the South African context (West 1991:161-180; Mosala 1989; Smit 1989; Draper and West 1989; and Lategan and Rousseau 1988). This paper continues with this work. In this paper I am concerned with the interface between the trained reader and the ordinary reader. More specifically, I am concerned to explore the responses of ordinary readers to the different modes of reading emerging from biblical scholarship. In Biblical Hermeneutics of Liberation: Modes of Reading the Bible in the South African Context I began this exploration (West 1991); this paper continues the exploration.
|
2022-09-28T14:40:34.645Z
|
22,231,655 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/BEHECO/ARM061",
"MAG": "2146696546",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Like any form of cooperative behavior, quorum sensing (QS) in bacteria is potentially vulnerable to cheating, the occurrence of individuals that contribute less but still profit from the benefits provided by others. In this paper, we explore the evolutionary stability of QS as a regulatory mechanism of antibiotics production in a spatially structured population, using cellular automaton (CA) modeling. QSg is supposed to regulate the excretion of a bacteriocin (anticompetitor toxin) in a population of bacteria polymorphic for the ability to produce and to be immune to the bacteriocin. Both the social interactions resulting from QS and the competitive interactions resulting from the bacteriocin excretion are supposed to be only effective at the local scale, that is, restricted to the immediately neighboring cells. This implies a rather diffuse kind of group selection. The CA model is contrasted to a model assuming no spatial structure but with otherwise identical assumptions. Our analysis predicts that QS as a regulatory mechanism of bacteriocin excretion is evolutionarily unstable when the competitive interactions between bacteriocin-producing, resistant, and sensitive strains only involve closely related strains which can share the signaling and responding genes involved in QS. However, when the competition is between unrelated strains and the QS alleles can only be carried by the bacteriocin-producing strains, stable QS may evolve provided its costs are small and the critical quorum threshold is neither too low nor too high. Copyright 2007, Oxford University Press.
|
2022-12-07T23:03:22.691Z
|
84,743,004 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/03650340903099676",
"MAG": "2022273510",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The specific surface area of soil (SSA) is crucial for the interaction of ions and water molecules with the soil particles. Therefore, many physical and chemical properties of soil are determined by its total specific surface area. Measurement of SSA is time-consuming and laborious; therefore, its estimation by a physical or an empirical model is preferred. The objectives of this investigation were: (i) To estimate the SSA of soils from the south of the Islamic Republic (IR) of Iran by considering spherical and cylindrical models for soil particles (physical model), and (ii) to develop a multivariate pedo-transfer function to estimate SSA based on the geometric mean (dg) and the standard deviation (σg) of the diameter of soil particles (empirical model). The results indicate that the physical model is superior to the multivariate pedo-transfer function in estimation of SSA. However, a power pedo-transfer function for is superior to the physical model and the multivariate pedo-transfer function for the estimation of SSA.
|
2022-12-15T22:17:17.988Z
|
12,643,162 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/01.CHI.0000194565.78536.BB",
"MAG": "1993027513",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
OBJECTIVE
To predict psychiatric hospital length of stay (LOS) for a sample of Illinois Department of Children and Family Services wards across 4 fiscal years.
METHOD
A prospective design was implemented using the Children's Severity of Psychiatric Illness scale, a reliable and valid measure of psychiatric severity, risk factors, youth strengths, and contextual/environmental factors. Data were collected for 1,930 hospital episodes across 44 hospitals from fiscal year 1998 through fiscal year 2001. Youths were screened for admission appropriateness by the Illinois Screening, Assessment, and Supportive Services (SASS) program. The Children's Severity of Psychiatric Illness was completed by SASS workers upon conclusion of their crisis interviews. In addition to completing the Children's Severity of Psychiatric Illness, SASS workers reported on demographic information and LOS.
RESULTS
The sample of 1,930 youths was randomly split to form development (n = 983) and validation (n = 947) samples. LOS was predicted using ordinary least squares regression. Thirty percent of the variance (F(19,666) = 16.6, p < .0001) in LOS was predicted for the development sample and 22% (F(14,657) = 14.6, p < .0001) was predicted for the confirmation sample. Hospital was the largest and most consistent predictor of LOS for both samples after controlling for clinical variables. Two hospitals accounted for approximately 10% of the variance in both samples (development beta = .273, p < .01 and beta = -.169, p < .01). Two SASS agencies also consistently predicted LOS (development beta = -.134, p < .05 and beta = .102, p < .05). No consistent changes in predictors of LOS occurred over time (FY98-FY01).
CONCLUSIONS
These findings suggest that nonclinical variables are the primary predictors of LOS in the Illinois system of care. In addition, these variables are consistent predictors over time. Quality assurance efforts might seek to further understand potential practice pattern variations across hospitals and SASS agencies.
|
2022-12-20T21:09:25.573Z
|
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