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255M
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85,323,416 |
{
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"DOI": "10.1111/J.1439-0426.2011.01749.X",
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|
Summary
Length–weight relationships (TW = a TLb) were estimated for fish species caught by bottom shrimp trawl north of Santa Catarina Island (Brazil) from October 2003 to September 2004. For three of the species this is the first LWR data in Brazil.
|
2022-12-23T02:19:45.344Z
|
52,949,502 |
{
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"ArXiv": null,
"DOI": "10.1590/1679-78251694",
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"license": "CCBY",
"status": "GOLD",
"url": "http://www.scielo.br/pdf/lajss/v13n1/1679-7825-lajss-13-01-00023.pdf"
}
|
In this work we present a simple, fast technique for generating particle packs at high packing ratios aiming at the simulation of granular compacts via the discrete element method (DEM). We start from a random sequence addition particle generation algorithm to generate a "layer" of non-overlapping spherical particles that are let to evolve dynamically in time under the action of "compacting" or "jamming" pseudo forces. A "layer-by-layer" approach is then followed to generate multiple layers on top of each other. In the end, very dense packs with pre-defined bulk shapes and sizes (e.g. rectangles in two dimensions and prisms in three dimensions) are achieved. The influence of rolling motion (with particle rotation and spin) along with inter-particle friction on the density and ordering of the generated packs is assessed. Both congruent and inhomogeneous packs (with respect to particle sizes) are created and their packing properties evaluated. We believe that simple techniques for fast generation of particle packs at high packing ratios are essential tools for the DEM simulation of granular compacts.
|
2022-12-23T02:21:49.993Z
|
32,307,004 |
{
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"DOI": "10.1097/scs.0b013e3180a03353",
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|
The aim of this study was to elucidate zygomaticofacial foramen (ZFF) relating to malar reduction surgery. Fifty-five dry skulls of adult Koreans were studied. A total of 100 (90.9%) ZFF were observed in 110 skulls. ZFF was variably more than one: one in 56 specimens (50.9%), 2 in 33 (30%), 3 in 10 (9%), and 4 in one (0.9%). ZFF was located 7.3 mm lateral and 3.7 mm inferior to P point, which was defined as crossing a line along the upper border of the zygomatic arch and a vertical line on the lateral orbital rim. The distance from the zygomatic suture to ZFF was 24.4 mm on average. ZFF was located 7.61 mm from the closest orbital rim. ZFF was located 13.0 mm from the nearest zygomatic angle (the junction of the zygomatic arch and lateral orbital rim). Most ZFF were within an ellipse of 15 mm in the major axis and 5 mm in the minor axis. The ellipse was 5 mm from P point. Our data suggest the osteotomy line in malar reduction should be placed at least 10 mm lateral to the lateral orbital rim.
|
2022-02-01T21:55:14.125Z
|
195,840,152 |
{
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"ArXiv": null,
"DOI": "10.1109/FTDCS.1988.26676",
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"license": null,
"status": null,
"url": null
}
|
The portable common tool environment (PCTE), an advanced, distributed software-engineering-environment-distribution-service designed to provide efficient, reliable, and transparent access to hardware and software resources across a network of heterogeneous workstations, is described. A client-server model of PCTE distribution, making use of networking facilities, (NFs), is presented. The design criteria for such a model are discussed, along with problems encountered during its implementation, especially regarding the object management system entities, distribution, and process distribution.<<ETX>>
|
2022-02-08T07:32:00.066Z
|
124,321,042 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4134/BKMS.2015.52.4.1297",
"MAG": "2397235640",
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}
|
We study Samelson products on models of function spaces. Given a map between 1-connected spaces and its Quillen model , there is an isomorphism of graded vector spaces . We define a Samelson product on .
|
2022-02-09T18:30:17.539Z
|
99,133,662 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1051/JCP/1989860031",
"MAG": "2463560953",
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"license": null,
"status": null,
"url": null
}
|
Cet article dresse un premier bilan des possibilites qu’offrent les electrodes modifiees par des films de polypyrroles N-substitues par des groupes mediateurs en electrocatalyse.
|
2022-02-10T12:00:08.094Z
|
61,529,639 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/30.628677",
"MAG": "2128403968",
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"status": null,
"url": null
}
|
A common hardware engine that performs the frequency to time domain transform for both MPEG and Dolby AC3 audio standards is presented. An integral part of the dual mode audio decoder, the cost-effective approach taken here requires minimal computation steps with due consideration of control, address generation, data pipelining, and the overall hardware structure.
|
2022-02-11T15:40:11.778Z
|
17,539,080 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/SISY.2010.5647101",
"MAG": "2074501678",
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"url": null
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|
In the paper, a medical application in determining the severity of respiratory distress in a patient in an intensive care unit is considered in a simplified version, based on fuzzy sets theory. An overview of previous results is given, as well as directions for further development of the application. In that framework, known models of fuzzy multi-criteria decision making are applied in two situations: the first, with all features of equal importance and without interaction between criteria, and the second, with interacting criteria. The practical usage of both approaches is shown. In the first case the Bellman-Zadeh's approach is used, and in the second case, the Choquet integral is used. The further development could include the model improvements dealing with interaction indices, as well as with the problem of identifying fuzzy measures. Some other directions for possible further work on the application considered are pointed out.
|
2022-02-13T00:23:22.919Z
|
33,986,011 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/UT.2015.7108253",
"MAG": "1508826750",
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"license": null,
"status": null,
"url": null
}
|
Beginning this year, as part of the Crossministerial Strategic Innovation Promotion Program, Next Generation Marine Resources Survey Technologies (Zipangu Plan for the Sea), tools for marine resources survey use will be developed. In this way, the world's first simple undersea work system that can be used for highly efficient sampling of seabed resources etc. will be built with, as its ultimate purpose, encouraging a great leap forward in the surveying of constituents of seabed resources and of their reserves etc. The authors are undertaking advanced research on underwater acoustic video cameras as part of their contribution to one of its themes, the development of an ROV based high-efficiency undersea work system. This ROV high-efficiency undersea work system is a mechanism that samples specimens by coring multiple points on a hard ocean bed. To make judgments about the location of the tip of the core cutter during coring, to clarify progress of the work, or to decide the next step, it is important to obtain visual information displayed in real time as three-dimensionally as images obtained by the human eye. So the authors have conducted advance research on acoustic video cameras to support underwater visibility, by developing acoustic image gathering technology that ensures visibility when the work has made the water turbid, and have also developed an image presentation method, in order to operate underwater machines.
|
2022-09-09T01:18:10.802Z
|
230,566,641 |
{
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"ArXiv": null,
"DOI": "10.30743/JHAH.V1I2.3343",
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"status": null,
"url": null
}
|
Abstract Giving a gift from parents to their children while still living according to the law is actually not wrong. However, in practice that occurs in the community, giving parents grants to their children is often a legal problem, namely the cancellation of grants, which often leads to legal settlement in court. Keywords : Perspective, Positive Law, Grant Cancellation. Abstrak Pemberian hibah dari orang tua kepada anaknya ketika masih hidup menurut hukum sebenarnya tidaklah salah. Akan tetapi, pada praktek yang terjadi di masyarakat, pemberian hibah orang tua kepada anaknya seringkali menjadi persoalan hukum, yakni terjadi pembatalan hibah, yang seringkali bermuara pada penyelesaian hukum di pengadilan. Kata Kunci : Perspektif, Hukum Positif, Pembatalan Hibah.
|
2022-09-27T16:17:02.255Z
|
547,948 |
{
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"ArXiv": null,
"DOI": "10.3389/fnhum.2013.00361",
"MAG": "2137040619",
"PubMedCentral": "3710954"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.frontiersin.org/articles/10.3389/fnhum.2013.00361/pdf"
}
|
Several current computational models of eye-movement control in reading posit a tight link between the eye and mind, with lexical processing directly triggering most “decisions” about when to start programming a saccade to move the eyes from one word to the next. One potential problem with this theoretical assumption, however, is that it may violate neurophysiological constraints imposed by the time required to encode visual information, complete some amount of lexical processing, and then program a saccade. In this article, we review what has been learned about these timing constraints from studies using ERP and MEG. On the basis of this review, it would appear that the temporal constraints are too severe to permit direct lexical control of eye movements without a significant amount of parafoveal processing (i.e., pre-processing of word n+1 from word n). This conclusion underscores the degree to which the perceptual, cognitive, and motor processes involved in reading must be highly coordinated to support skilled reading, a par excellence example of a task requiring visual-cognitive expertise.
|
2022-12-17T21:45:58.488Z
|
10,394,201 |
{
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"ArXiv": null,
"DOI": "10.1371/journal.pone.0073007",
"MAG": "2030409010",
"PubMedCentral": "3765206"
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"license": "CCBY",
"status": "GOLD",
"url": "https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0073007&type=printable"
}
|
Humpback whales migrate between relatively unproductive tropical or temperate breeding grounds and productive high latitude feeding areas. However, not all individuals of a population undertake the annual migration to the breeding grounds; instead some are thought to remain on the feeding grounds year-round, presumably to avoid the energetic demands of migration. In the Southern Hemisphere, ice and inclement weather conditions restrict investigations of humpback whale presence on feeding grounds as well as the extent of their southern range. Two years of near-continuous recordings from the PerenniAL Acoustic Observatory in the Antarctic Ocean (PALAOA, Ekström Iceshelf, 70°31’S, 8°13’W) are used to explore the acoustic presence of humpback whales in an Antarctic coastal area. Humpback whale calls were present during nine and eleven months of 2008 and 2009, respectively. In 2008, calls were present in January through April, June through August, November and December, whereas in 2009, calls were present throughout the year, except in September. Calls occurred in un-patterned sequences, representing non-song sound production. Typically, calls occurred in bouts, ranging from 2 to 42 consecutive days with February, March and April having the highest daily occurrence of calls in 2008. In 2009, February, March, April and May had the highest daily occurrence of calls. Whales were estimated to be within a 100 km radius off PALAOA. Calls were also present during austral winter when ice cover within this radius was >90%. These results demonstrate that coastal areas near the Antarctic continent are likely of greater importance to humpback whales than previously assumed, presumably providing food resources year-round and open water in winter where animals can breathe.
|
2022-12-22T01:07:54.722Z
|
143,811,432 |
{
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"ArXiv": null,
"DOI": "10.12968/sece.2013.6.1807",
"MAG": "1981110465",
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"status": null,
"url": null
}
|
Sadly, new teachers must be aware of the dangers of pupils who make false accusations. Dorothy Lepkowska looks at some recent cases and offers advice on how to avoid being falsely accused.
|
2022-02-09T07:20:16.896Z
|
2,938,339 |
{
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"ArXiv": null,
"DOI": "10.1109/GCCE.2013.6664916",
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"url": null
}
|
As the height of buildings grows, the demand of enhancing transportation capacity in buildings has been increasing. One of the solutions could be increasing the number of elevator shafts. A dilemma, however, exists that most of the floor space is occupied by the elevator shafts if a lot of elevator shafts were installed. Therefore, multi-car elevator (MCE) systems, which have several elevator cars in a shaft, attracts people's attention. Optimization of car control and call assignment is necessary to control MCE systems safety and transport passengers rapidly. We have been studying the optimization problem, which is called a car control and assignment problem (CCAP) in MCE systems, and proposed Integer Program (IP) and Mixed Integer Program (MIP). They, however, have a problem that it takes long time to solve. In this paper, we propose a new method, which is called a Hybrid solving Method for Mce systems (HMM), solving the CCAP using Mixed Integer Program (MIP) and Constraint Program (CP), and evaluate it through computational experiments.
|
2022-02-13T13:04:47.486Z
|
92,689,984 |
{
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"ArXiv": null,
"DOI": "10.1246/CL.1994.669",
"MAG": "625416498",
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"url": null
}
|
[35](1,2,3,4,5)Cyclophane 3 was synthesized by an acid-catalyzed eyclization between a pseudogeminally substituted acetyl group and a chloromethyl group of a tetra-bridged compound followed by two-step hydrogenation of the resulting penta-bridged bromo-olefin. 3 shows the strongest transannular π–π interaction among [m.n]- and multibridged benzenophanes synthesized so far. 3 is conformationally mobile at room temperature in CD2Cl2, and two conformers 3a and 3b are observed at −90 °C.
|
2022-09-13T15:17:35.416Z
|
86,110,645 |
{
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"ArXiv": null,
"DOI": "10.22201/IB.20078706E.2011.4.678",
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|
En zonas tropicales secas, el arbol de la moringa (Moringa oleifera Lam.) es objeto de gran atencion por parte de los productores, en tanto que crece el numero de proveedores que promueven la planta como panacea. Ante esta situacion, es necesario separar los usos que estan identificados y fundamentados por el conocimiento cientifico de aquellos que no lo estan. Con base en el presente estudio y en la literatura, se presenta un resumen de las bases cientificas que sustentan algunos de los beneficios de la moringa, en la medida de lo que hasta hoy se conoce. Los analisis comprueban que la harina de hoja de la moringa se compara favorablemente con la leche en polvo en cuanto a sus componentes de proteina y de calcio y tiene, adicionalmente, un alto contenido de vitamina A. Ademas de su valor nutritivo, las hojas son ricas en antioxidantes, entre los cuales destacan los isotiocianatos, los cuales parecen presentar propiedades anticancerigenas, hipotensoras, hipoglucemiantes y antibioticas. Las concentraciones de factores antinutritivos en las hojas, tales como inhibidores de proteasas, taninos, saponinas y lectinas, son insignificantes. La mayoria de los estudios sobre las cualidades beneficas de la moringa se han llevado a cabo in vitro o en animales; por lo tanto, se desconocen las dosis necesarias para producir algun efecto benefico en humanos. Sin embargo, dado que los beneficios potenciales son muchos y los niveles de sustancias antinutricionales bajisimos, no encontramos argumentos en contra del consumo de la planta. En resumen, Moringa oleifera es un alimento nutritivo y benefico que ofrece caracteristicas muy atractivas para establecer su cultivo en comunidades sostenibles en el tropico seco de Mexico y otros paises de Latinoamerica.
|
2022-12-15T14:57:17.787Z
|
33,339,128 |
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"DOI": "10.1109/ICESA.2015.7503443",
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|
Energy audit is a primary study that identifies energy use among various services and provides opportunities for energy conservation. Energy auditing is an integral part of energy conservation and energy management is also part of conservation. It is an initial study in establishing an energy management programme. This paper reviews the initial attempts to understand the energy consumption patterns in a residential building and to reduce the energy consumptions. A case study is included to investigate the reduction in energy consumption per unit in order to make building energy efficient. A feasibility study is done to check the increase in construction cost to gain energy efficiency credits for LEED certification. Payback calculations are done to understand the Investments required and hence feasibility is confirmed.
|
2022-12-19T03:33:12.455Z
|
13,160,691 |
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"ArXiv": null,
"DOI": "10.1089/jpm.2013.0453",
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"license": null,
"status": "GREEN",
"url": "https://repository.escholarship.umassmed.edu/bitstream/20.500.14038/47957/3/Pieters_jpm_2013_0453.pdf"
}
|
I grew up hearing stories about my grandmother, a missionary and an American-trained surgeon, who brought her doctoring skills to Korea at the turn of the twentieth century. She spent her first few months there learning the language and customs of this ancient kingdom where she’d spend the rest of her life. Working in a preantibiotic era, supportive care was an important part of her practice. Keeping her patients comfortable was sometimes the best she could offer (see Fig. 1). The personal side of medicine, often known as high touch, was as important as her surgical technique. Thus began my appreciation of the interplay between high tech and high touch. Not surprisingly, as an undergraduate I majored in anthropology and East Asian studies. When later accepted to medical school, I saw myself as a family practitioner. A chance conversation with a radiation oncologist on a shared car ride and a subsequent elective in the field changed my career course. Radiation oncology seemed the perfect way to merge some of my major life influences. I would be able to enlist my math and physics skills, courtesy of my math teacher father, into the service of hands-on doctoring like my grandmother, or so I thought. Radiation oncology has long been on the leading edge of technological advances in treatment planning and delivery systems. During my residency, computerized tomography (CT) imaging became more readily available. Today, CT-based volumetric planning with the fusion of magnetic resonance imaging(MRI)andpositron-emitting tomography(PET)scans, automated beam-shaping devices, and daily field imaging are common in practice. In plain language, with their current tools, radiation oncologists can customize treatment to accurately target the tumor and better spare surrounding normal tissue. During my residency, rigorous attention was given to mastery of the technical aspects of radiation oncology, but supportive care, though deemed important, was never given the same intense focus. You learned how to address treatmentrelated side effects on a case-by-case basis. Instruction and feedback on communication skills were not formalized and rarely mentioned, except when a major faux pas occurred
|
2022-12-23T02:05:21.926Z
|
17,531,407 |
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"DOI": "10.1177/2050312116660116",
"MAG": "2499120702",
"PubMedCentral": "4962519"
},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://doi.org/10.1177/2050312116660116"
}
|
Objective: Nitinol stenting could bring the better outcome in endovascular therapy for femoropopliteal disease. However, it might be expected that recent marked advances in both device technology and operator technique had led to improved efficacy of balloon angioplasty even in this segment. The aims of this study were to evaluate the clinical impact of balloon angioplasty for femoropopliteal disease and make risk stratification clear by propensity score matching analysis. Methods: Based on the multicenter retrospective data, 2758 patients (balloon angioplasty: 729 patients and nitinol stenting: 2029 patients), those who underwent endovascular therapy for femoropopliteal disease, were analyzed. Results: The propensity score matching procedure extracted a total of 572 cases per group, and the primary patency rate of balloon angioplasty and nitinol stenting groups after matching was significantly the same (77.2% vs 82.7% at 1 year; 62.2% vs 64.3% at 3 years; 47.8% vs 54.3% at 5 years). In multivariate Cox hazard regression analysis, significant predictors for primary patency were diabetes mellitus, regular dialysis, cilostazol use, chronic total occlusion, and intra-vascular ultra-sonography use. The strategy of balloon angioplasty was not evaluated as a significant predictor for the primary patency. After risk stratification using five items (diabetes mellitus, regular dialysis, no use of intra-vascular ultra-sonography, chronic total occlusion, and no use of cilostazol: the DDICC score), the estimated primary patency rates of each group (low, DDICC score 0–2; moderate, DDICC score 3; high risk, DDICC score 4–5) were 88.6%, 78.3%, and 63.5% at 1 year; 75.2%, 60.7%, and 39.8% at 3 years; and 66.0%, 47.1%, and 26.3% at 5 years (p < 0.0001). The primary patency rate of balloon angioplasty and nitinol stenting groups was significantly the same in each risk stratification. Conclusion: This study suggests that balloon angioplasty does not have inferiority to nitinol stenting but does have favorable efficacy in femoropopliteal segment by careful risk stratification with the recent advance of technique.
|
2022-12-30T00:24:25.848Z
|
220,001,585 |
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"DOI": "10.1136/bmj.1.2212.1238",
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}
|
THE ROYAL ARMY MEDICAL CORPS. THE following is the text of an official document which, we understand, will shortly be issued by the War Office to the Deans of all the medical schools in the United Kingdom: The Army Medical Service, under the Royal Warrant of 1902. gives greatly increased advantages to officers of the Royal Army Medical Corps, and offers an attractive career to young medical men. The provisions of the new warrant ensure: I. r3ufficient pay to enable the officer to support himself from the date of his entering the service. (See Appendix, Schedule of Pay, p. 1239.) 2. Increased rates of pay to officers in charge of hospitals, or when selected for specialist appointments. 3. Opportunities of professional improvement by work in the Royal Army Medical College, by the study of disease in foreign countries, and by original research. 4. Advancement on account of professional ability and merit, and not only by order of seniority. 5. Permission to retire at the end of three years' service, and to join the reserve of the corps, receiving a small annual honorarium. Permission may be given to officers of this reserve to rejoin the corps within a certain period. 6. The certainty of obtaining a gratuity of £i,ooo on retirement after nine years' service, and of obtaining a pension of /i a day, on retirement after twenty years' service, with increased rates of pension after longer terms. Pensions at higher rates are paid to officers who retire on account of injuries received when on duty. Pensions are granted to the widows and children of officers.
|
2022-01-27T13:15:05.906Z
|
83,845,234 |
{
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"DOI": "10.1017/S0021859600057622",
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|
Summary The growth and yield of four varieties of field beans were studied in field experiments in 1967 and 1968. Seed yield of the varieties Albyn Tick, Herz Freya, Blue Rock and Maris Bead were similar (averaging 6600 kg/ha) in 1967, but in 1968 Albyn Tick and Herz Freya (averaging 6400 kg/ha) outyielded Maris Bead (5700 kg/ha). Yield in both seasons were substantially more than the national average yields for Britain (about 3000 kg/ha). In 1968, yields were 40% greater at 57 plants/m2 (7100 kg/ha) than at 36 plants/m2 (5100 kg/ha). Yield was closely correlated with number of pods/plant. The number of pods/node regulated this rather more than the numbers of nodes forming pods. Mean seed weight and seed number/pod varied little between plant densities but variety means were significantly different. Maximum numbers of immature pods were present in late June. By mid-July 35% of the immature pods had shed, mainly from the middle and top of the range of podbearing nodes.
|
2022-09-14T10:01:15.215Z
|
128,392,167 |
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"DOI": "10.1002/wrcr.20283",
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|
We investigated the effect of the Three Gorges Project and other dams on the load of phosphorus (P) to the middle and lower Yangtze River (MLY) and discussed the alteration of P on the ecosystem of the MLY. We collected data for continuous flow and sediment over the past 60 years and observed the concentrations of total P (TP) and particulate P (PP) in the pool reaches of the Three Gorges Reservoir (TGR), both before and after the impoundment in 2003. As a result, we obtained highly positive correlations between P and sediment and revealed two changes that were caused by the impoundments: (1) the sediment load to the MLY decreases by 91% and the river becomes almost clear; and (2) the loads of TP and PP to the MLY are sequestered by 77% and 83.5% annually and 75% and 92% in dry seasons, respectively. Because P was the limiting nutrient for bioactivity in the MLY before 2003, such significant reductions, along with the many other consequences of the dams, will not only further reduce the bioavailability of P but also increase the existing high ratio of nitrogen (N) to P. Therefore, it is quite possible to alter the nutrient regime and reduce the aquatic primary productivity of the MLY. Given that many large dams with huge reservoirs are under construction or planned upstream and elsewhere, studies focused on the long‐term effects of sediment and P reduction deserve a high priority for the protection of lowland rivers and aquatic ecosystems.
|
2022-12-02T16:54:58.077Z
|
144,373,660 |
{
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"DOI": "10.1093/RESEVAL/RVT008",
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"url": null
}
|
How to assess research quality in the humanities is an intricate question. Despite the recent efforts of many initiatives, the measurement and assessment of research quality still faces strong opposition from humanities scholars, indicating that currently used evaluation schemes and tools are not tailored well enough to humanities disciplines. We have collected quality criteria from scholars in Switzerland and at League of European Research Universities (LERU) in the three disciplines, German literature studies, English literature studies and art history with a multi-round Delphi survey. The first Delphi round resulted in a comprehensive list of 19 criteria of good research specified by 70 aspects. Although 10 of these criteria are well known and commonly used in various evaluation schemes, nine criteria are not, or at least not frequently, employed in evaluation schemes. In the second Delphi round, consensual criteria and aspects (i.e. items that were clearly approved by a majority and disapproved by very few scholars) were identified in each discipline. Specifically, 11 criteria reached consensus in all three disciplines (shared criteria), six criteria were consensual in only one or two disciplines (discipline-specific criteria) and two criteria were not consensual in any discipline (i.e. 'productivity' and 'relation to and impact on society'). The results of this study corroborate previous findings that researchers have not yet adopted Mode 2-related assessment criteria. Implications for research assessment are being discussed. The focus lies in particular on the mismatch of criteria between evaluators and scholars as well as on an approach to bridge such a mismatch. Copyright The Author 2013. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com, Oxford University Press.
|
2022-12-25T13:15:54.144Z
|
102,150,273 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/IE500139K",
"MAG": "2314020440",
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},
"license": null,
"status": null,
"url": null
}
|
The sorption of Pb(II) onto polyacrylamide zirconium(IV) iodate, a hybrid inorganic–organic material, has been studied through the batch equilibrium technique. The experimental equilibrium data have been analyzed using Langmuir, Freundlich, Temkin, and Dubinin–Radushkevich isotherm models. The accuracy of the fit of isotherm models to the experimental equilibrium data was assessed using error analysis.The Temkin model yields the best fit between experimental and simulated data. The kinetic data obtained at different concentrations have been analyzed using pseudo-first-order, pseudo-second-order, and intraparticle diffusion models. The experimental data obey the pseudo-second-order kinetic model. The plot of qt versus t1/2 suggests that intraparticle diffusion is not the sole rate-controlling step; some degree of boundary layer diffusion is also involved. The calculated thermodynamic parameters ΔG°, ΔH°, and ΔS° indicate that the adsorption of Pb(II) onto the sorbent is a spontaneous, endothermic, and phys...
|
2022-12-28T18:10:51.750Z
|
143,134,409 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.14712/18023061.90",
"MAG": "1963999969",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://doi.org/10.14712/18023061.90"
}
|
Srovnani knih: KEULARTZ, J. (1998). TheStruggle for Nature. A Critique of Radical Ecology. London/New York: Routledge. PALOUS, R. (1996). Totalismus a holismus. Praha: Karolinum. Odkaz na přeloženou kapitolu Holismus a totalitarismus z knihy Jozefa Keulartze lze nalezt zde: Zapas o přirodu: kritika radikalni ekologie. Paideia: 2/III/2006 ISSN 1214-8725
|
2022-02-09T07:40:22.397Z
|
216,467,431 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.31686/ijier.vol7.iss12.2099",
"MAG": "3015896727",
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},
"license": "CCBYND",
"status": "GOLD",
"url": "https://ijier.net/ijier/article/download/2099/1438"
}
|
"A picture is worth a thousand words". Internet plus has brought people into the era of picture reading. Pictures and videos are everywhere. And dynamic video has the characteristics of sound, sound and documentary. It has become a popular media form for the public. Therefore, mobile phone video shooting and production are convenient, and the popularization of video production and dissemination has become inevitable. However, the creation of artistic and innovative video works requires producers to master certain visual thinking methods in addition to film montage theories and techniques. The article briefly outlines the forming process of the concept of visual thinking, and proposes advanced methods of visual thinking: intuitive method, selection method, discovery method, and inquiry method. In the process of video production, some methods of visual thinking are analyzed through a case, such as the visualization of textual information, the figuration of image, the logic of concreteness, and the systematization of logic. We have studied practical visual thinking training methods, from the three stages of video production: script creation, shooting practice, and video packaging,
|
2022-02-08T02:15:09.574Z
|
163,959,034 |
{
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"DOI": "10.11588/heidok.00007911",
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}
|
Zusammenfassung Die Diskussion uber die Wechselwirkungen zwischen internationalem Handel und der Nutzung naturlicher Ressourcen hat ihren Ursprung zu Beginn der 70er Jahre, als eine forcierte Umweltpolitik seitens der OECD-Lander eine Verschlechterung der Wettbewerbsposition umweltintensiv produzierender Sektoren im internationalen Vergleich vermuten lies. Fur die okonomische Theorie bedeutete dies die Notwendigkeit, die Annahme einer geschlossenen Volkswirtschaft innerhalb der Umweltokonomie beziehungsweise innerhalb von Untersuchungen mit umweltokonomisch orientierter Fragestellung aufzugeben und die Nutzung naturlicher Ressourcen innerhalb der Ausenwirtschaftstheorie explizit zu berucksichtigen. Die vorliegende Arbeit leistet zu diesem Themenkomplex einen Beitrag und umfasst drei Schwerpunkte: Teil I befasst sich mit der Frage nach den Effekten des internationalen Handels auf die Nutzung naturlicher Ressourcen. Die Arbeit grenzt sich mit einem ganzheitlichen Ansatz von der Mehrzahl okonomischer Untersuchungen ab, die die Auswirkungen umweltpolitischer Masnahmen auf den internationalen Handel untersuchen, jedoch die Frage nach den Effekten des internationalen Handels auf die Ressourcennutzung meist uberhaupt nicht oder aber nur am Rande abhandeln. Zum Zwecke dieser ganzheitlichen, systematischen Darstellung und - soweit moglich - einer wohlfahrtsokonomischen Bewertung werden die Auswirkungen einer Handelsliberalisierung in die Teilkomponenten Wachstums-, Struktur- und Wettbewerbseffekte zerlegt und deren mogliche Auswirkungen jeweils auf der Produktions- und Konsumebene im Hinblick auf die Nutzung nationaler und globaler naturlicher Ressourcen uberpruft. Ziel ist die Identifizierung von Ineffizienzen zur Begrundung wirtschaftspolitischen Handlungsbedarfs. Innerhalb der einzelnen Fragestellungen in Teil I werden weitest moglich theoretische und empirische Ergebnisse gegenubergestellt. Diese Darstellung erlaubt es schlieslich, auch andere Beitrage zum Thema in eine systematische Struktur einzuordnen. Die Ergebnisse zeigen, dass bei Berucksichtigung naturlicher Ressourcen die grundsatzliche Aussage einer Wohlfahrtssteigerung durch Handelsliberalisierung nicht mehr uneingeschrankt haltbar ist, andererseits eine optimale Allokation naturlicher Ressourcen erst durch internationalen Handel moglich wird. Auf empirischer Ebene wird deutlich, dass internationale Waren- und Kapitalstrome weitaus weniger sensibel auf umweltpolitische Masnahmen reagieren als zunachst zu vermuten ware. In Teil II werden die Implikationen fur die Handelspolitik diskutiert. Dabei helfen zunachst die in Teil I gewonnenen Erkenntnisse, ein besseres Verstandnis fur die Argumente und Motivlagen der Befurworter und Gegner (Umweltschutzer, Staat, Industrie und Konsumenten) handelsbeschrankender Masnahmen zu gewinnen. Anschliesend werden verschiedene tarifare und nicht-tarifare Handelshemmnisse auf ihre okonomische Effizienz, ihre Effektivitat im Hinblick auf okologische Ziele, ihre Protektionswirkung und ihre Umsetzungsmoglichkeit in der Praxis hin uberpruft und alternativen wirtschaftspolitischen Masnahmen gegenubergestellt. Es zeigt sich, dass handelspolitische Instrumente nicht nur aufgrund ihrer verzerrenden Wirkung, geringen Reichweite und hohen Missbrauchsmoglichkeit ungeeignet zur Erreichung der o.g. Ziele sind: Bereits die Schwierigkeiten der praktischen Umsetzung zeigen sehr deutlich die Grenzen handelsbeschrankender Masnahmen auf. Als Alternativen erscheinen eine ausenhandelsorientierte Umweltpolitik und eine umweltorientierte Ausenhandelspolitik, die Kooperation mit Entwicklungslandern und multinationalen Unternehmen sowie eine internationale Festlegung und Zertifizierung von Umweltstandards als erfolgsversprechender Losungsansatz. Die Arbeit schliest mit einem Fallbeispiel zu Indien (Teil III). Primar wird untersucht, inwieweit sich die Ausenhandelsstruktur Indiens nach der Handelsliberalisierung zu Beginn der 90er Jahre im darauf folgenden Jahrzehnt zu Gunsten umweltintensiver Sektoren entwickelt hat. Neben der geographischen Abgrenzung unterscheidet sich die vorliegende Arbeit in der Empirie von anderen Untersuchungen durch die Betrachtung von Industriesektoren des verarbeitenden Gewerbes auf stark disaggregiertem Niveau und durch eine Differenzierung zwischen arbeits- und kapitelintensiven Sektoren. Die indische Exportquote hat sich in den 90er Jahren verdoppelt und ist erwartungsgemas in den arbeitsintensiven Sektoren hoher als in den kapitalintensiven Sektoren. Sowohl bei der Betrachtung der Exportquote, der Wachstumsrate der Exportquote und beim RCA-Index konnten wesentliche Strukturveranderungen im Bereich eines Umweltschutzkostenniveaus zwischen 2,5% und 3,5% gemessen am Bruttoproduktionswert festgestellt werden. Dies mag auf die Existenz eines Schwellenwertes hindeuten, ab dem die Umweltschutzkosten die internationale Wettbewerbsfahigkeit eines Sektors determinieren.
|
2022-02-08T20:41:07.769Z
|
225,781,450 |
{
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"DOI": "10.18290/rnp20301-10",
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},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://ojs.tnkul.pl/index.php/rnp/article/download/12685/12461"
}
|
Zasada salus animarum jako istota kontradyktoryjności w systemie prawa kanonicznego
Zasada kontradyktoryjności jest warunkiem zaistnienia iudicium. Do powstania każdego proce- su, w tym również kanonicznego procesu o nieważność małżeństwa, potrzebne jest bowiem czyjeś twierdzenie wyrażające wolę realizacji swojego uprawnienia z jednoczesnym zaistnieniem twierdzenia przeciwnego, które również w swej treści wyraża wolę realizacji tego samego uprawnienia. W tym czasie, gdy te dwa sprzeczne ze sobą twierdzenia zaistnieją jednocześnie przed sędzią kościelnym, powstaje spór, który następnie może przekształcić się w iudicium.
Taką wolę rozumienia procesu kanonicznego jako kontradyktoryjnego, wyraża również Papież Franciszek w MIDI, przypominając dotychczasowe unormowania i reformując jedynie te procedury, które tego wymagały zgodnie z duchem czasu. Wprowadzenie tych zmian ma na celu pozbycie się z treści iudicium jedynie tego, co się zdewaluowało, przy czym trzon kontradyktoryjności pozostaje niewzruszony. Papież Franciszek pisze w MIDI: „…troska o zbawienie dusz, która – zarówno dzisiaj, tak jak w przeszłości – pozostaje najwyższym celem instytucji, ustaw i prawa, skłania Biskupa Rzymu do przedstawienia biskupom niniejszego aktu reformy”. Takie właśnie uzasadnienie staje u podstaw reformy Franciszkowej procesu kanonicznego opartego na zasadach procesowych.
|
2022-06-16T18:27:45.472Z
|
81,631,672 |
{
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"ArXiv": null,
"DOI": "10.1183/13993003.CONGRESS-2018.PA5267",
"MAG": "2905884801",
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"license": null,
"status": null,
"url": null
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|
Delay in diagnosing tuberculosis (TB) can result in greater morbidity, mortality, and exacerbates disease burden in underserved groups. Prompt diagnosis and treatment prevents transmission, so it is concerning that 59% of cases regionally started treatment >2 months after symptom onset in 2016 (Public Health England, TB in England 2017 Report). This project aimed to review Enhanced Surveillance System (ETS) data 2013-16 to describe socio-demographic factors contributing to diagnostic delay in Yorkshire & Humber (YH). Data on variables including sex, ethnicity, social risk factors, socio-economic status (SES) and smoking was extracted for all YH cases notified in 2013-16. Dependent variables comprised median time from symptom onset to: presentation to healthcare services (patient delay), and diagnosis and treatment start dates (healthcare system delay; HSD). Results were also stratified by place of birth and social risk factors. Of 1961 cases, median time to presentation was 31 days (IQR 7-74), time to diagnosis 82 days (41-148) and time to treatment start 84 days (44-153). Thus HSD comprised the majority of delay regionally. The median difference of 2 days between diagnosis and treatment start indicates treatment is commenced promptly after diagnosis. All delays were longer for women than men, smear-negative cases vs positive, and for smokers. Delays were also longer in areas of lower TB incidence. Cases with higher SES, and no social risk factors had longer delays. HSD was longer for non-UK born vs UK born, White vs Pakistani, and UK-born Whites vs non-UK born; likely reflecting lower clinical suspicion. Recommendations were made to decrease the disproportionate delay in the aforementioned populations regionally.
|
2022-07-11T00:58:36.416Z
|
32,092,662 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1039/c0an00642d",
"MAG": "2043172171",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "http://ntur.lib.ntu.edu.tw/news/agent_contract.pdf"
}
|
Cluster ion sputtering has been proven to be an effective technique for depth profiling of organic materials. In particular, C(60)(+) ion beams are widely used to profile soft matter. The limitation of carbon deposition associated with C(60)(+) sputtering can be alleviated by concurrently using a low-energy Ar(+) beam. In this work, the role of this auxiliary atomic ion beam was examined by using an apparatus that could analyze the sputtered materials and the remaining target simultaneously using secondary ion mass spectrometry (SIMS) and X-ray photoelectron spectrometry (XPS), respectively. It was found that the auxiliary 0.2 kV Ar(+) stream was capable of slowly removing the carbon deposition and suppresses the carbon from implantation. As a result, a more steady sputtering condition was achieved more quickly with co-sputtering than by using C(60)(+) alone. Additionally, the Ar(+) beam was found to interfere with the C(60)(+) beam and may lower the overall sputtering rate and secondary ion intensity in some cases. Therefore, the current of this auxiliary ion beam needs to be carefully optimized for successful depth profiling.
|
2022-07-25T21:12:35.905Z
|
7,898,276 |
{
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"ArXiv": null,
"DOI": "10.1136/HRT.7.2.57",
"MAG": "1981376024",
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},
"license": null,
"status": null,
"url": null
}
|
In 1943 when reporting a case of congenital heart block with dextrocardia (Leys, 1943) I discussed the differential diagnosis of acquired and congenital heart block. It was remarked that complete heart block due to diphtheria (and probably other infections also) was almost always fatal, and that.nearly all cases of complete heart block in children and young adults were congenital. Fishberg (1940) with his very extensive practice, had seen only one patient surviving the appearance of complete heart block in diphtheria: he referred to a study by Stechner in 1928 of 19 cases, all fatal, and to a study by Jones and White in 1927 of 100 patients after severe diphtheria, none of whom had evidence of heart disease at the time of their examination. Hoskin (1926) found various minor post-diphtheritic cardiographic changes in 16 cases following severe attacks, but found no conduction defects. I now report a case of complete dissociation of auricle and ventricle in a married woman of 25 who had severe diphtheria at the age of 10 with palatal and ocular palsies. She reports that her heart was said to have been affected at that time, and that it was later remarked to her, when she had cerebrospinal fever at the age of 22, that she had a slow pulse. No comment on her pulse rate was made when she had appendicectomy at a cottage hospital at the age of 18. She was referred to the Royal Northern Infirmary, Inverness, because of attacks of syncope; these had began to appear shortly after an illness in which she had sore throat and joint pains. She remained in bed for only a few days. A similar illness had occurred two years previously. The attacks consisted of a choking sensation in the throat, pain and a tight sensation in the chest, followed by transient loss of consciousness, and later by vomiting. The heart rate at rest is either 36 or 48; other rates are not found. After exercise it rises
|
2022-12-02T11:49:40.427Z
|
22,809,234 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/HEP.1840030602",
"MAG": "2034320774",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The prognostic significance of a battery of clinical, laboratory, and histological indicators was assessed in relation to mortality risk in a 1‐year study of 253 patients with alcoholic liver disease, of whom 51 died within such time. The relative risk associated with each abnormality was calculated. A number of abnormalities was found to be statistically associated with a higher risk of death. Among the clinical abnormalities, these were: collateral circulation, edema, ascites, encephalopathy, spider nevi, anorexia, and weakness. Among the laboratory tests, these were: albumin, bilirubin, hemoglobin, abnormal prothrombin time, and alkaline phosphatase. Two hundred and sixteen of these patients had liver biopsies in which the quantifiable abnormalities were scored. Among the histological findings, the alterations significantly related to mortality were necrosis, Mallory, and inflammation, while the presence of cirrhosis per se did not influence the mortality risk. The relative risk factors for mortality associated with the histological alterations were lower than those derived from clinical or laboratory measurements. The advantage of using only clinical and laboratory items to derive a global, quantitative expression of severity is discussed. The relative mortality risks provided a means of calculating a “unit of severity” for each clinical and laboratory abnormality. A combined clinical and laboratory index (CCLI) results when these mortality‐risk units are added. Such a combined index had a quasi‐linear relationship with the risk of mortality for the complete population. This method compared well with severity scores derived from computerized, linear step‐wise discriminant function (SDF) analysis and from a logistic regression (LR) analysis. The factors chosen to have independent prognostic significance by the SDF analysis were: encephalopathy, albumin, prothrombin time, and hemoglobin, while only encephalopathy, albumin, and hemoglobin were chosen by the LR analysis. Within a range of values, LR can provide a good discrimination in relation to mortality, similar to that observed for the CCLI in its complete range. However, there are some advantages to the CCLI method vs. the LR or SDF analyses. The CCLI is less susceptible to being unduly influenced by a nonspecific effect of treatment on the items chosen than the SDF and LR analyses, as the CCLI contains a large number of factors. Obtaining a single‐severity score such as the CCLI is of value in: (a) assessing the effectiveness of treatment modalities; (b) analyzing the success of randomization; (c) separating cohorts of different severity, and (d) comparing new liver tests, histological abnormalities, or specific biological events with the severity of alcoholic liver disease.
|
2022-12-12T11:21:59.832Z
|
95,824,344 |
{
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"ArXiv": null,
"DOI": "10.1080/02772240701630588",
"MAG": "2026528045",
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"license": null,
"status": null,
"url": null
}
|
In the past several years a number of inadequately substantiated reports appeared in the popular media, asserting that lead (Pb) found in Beethoven's hair indicated that he was a victim of Pb poisoning and suggesting that lead played a role in his deafness and illnesses. This article reviews critically a recent report of the longitudinal distribution of Pb along individual hairs belonging to Beethoven by Dr Reiter 1, who interprets the Pb concentration profile of an individual hair in terms of several hypothetical occurrences which might have exposed Beethoven to lead during the last few months of his life and concludes that the resulting Pb poisoning caused his death. This hypothesis is, however, in need of substantiation by additional data since it is at variance with the known kinetics of Pb in blood and because the Pb content of hair is recognized as a problematical and unreliable biomarker of lead absorption, in part, because it is not possible to exclude exogenous Pb contamination in the specimen. In view of Beethoven's extraordinarily well-documented medical history and autopsy report, briefly summarized here, and in the absence of persuasive evidence that Beethoven suffered from lead disease, it is concluded that lead did not contribute significantly to his deafness, illnesses, or death.
|
2022-12-12T11:43:37.394Z
|
247,168,978 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1177/10225536221078622",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://journals.sagepub.com/doi/pdf/10.1177/10225536221078622"
}
|
Purpose: Aspiration pneumonia is a critical issue. General anesthesia may suppress the airway’s protective reflex. However, aspiration pneumonia is also observed in patients who undergo hip fracture surgery under spinal anesthesia. The aim of this study was to investigate the relationship between anesthesia methods and aspiration pneumonia as well as the predictive factors of aspiration pneumonia in elderly patients undergoing hip fracture surgery. Methods: The medical records of 19,809 patients aged ≥60 years who underwent hip fracture surgery under general or spinal anesthesia were reviewed. After propensity score matching, the anesthesia methods affecting the occurrences of aspiration pneumonia and other complications were investigated via logistic regression and instrumental variable analyses. Predictive factors of aspiration pneumonia were also investigated in all subjects using a multivariable logistic regression analysis. Results: Among the 11,673 general anesthesia patients and 8136 spinal anesthesia patients, aspiration pneumonia occurred in 356 patients (1.8%). Post-propensity score matching the incidences of aspiration pneumonia with general and spinal anesthesia were 1.8% and 1.5%, respectively (p = 0.158); other pulmonary complications were 1.5% and 1.5%, respectively (p = 0.893); and the mortality rates were 1.4% and 1.2%, respectively (p = 0.219). The predictive factors of aspiration pneumonia were advanced age, male sex, lean body, cerebrovascular disease, dementia, and dependency for activities of daily living (eating). Conclusion: Spinal and general anesthesia showed similar incidences of aspiration pneumonia in elderly hip fracture surgery. Regardless of the anesthesia method, great care should be taken, especially in elderly patients with the identified predictive factors.
|
2022-12-16T20:56:40.332Z
|
25,744,770 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1095/biolreprod.103.016360",
"MAG": "2154374319",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://academic.oup.com/biolreprod/article-pdf/69/5/1472/10586172/biolreprod1472.pdf"
}
|
Abstract During pregnancy, the villous trophoblast develops from the fusion of cytotrophoblastic cells (CT) into a syncytiotrophoblast (ST), supporting the main physiological functions of the human placenta. Connexin43 (Cx43) is demonstrated in situ and in vitro in the villous trophoblast between CT and between CT and ST. Moreover, the presence of a gap junctional intercellular communication (GJIC) during in vitro trophoblast differentiation was previously demonstrated. Because the exchange of molecules through gap junctions is considered to play a major role in the control of cell and tissue differentiation, we studied the effects of a gap junctional uncoupler, heptanol, on morphological and functional trophoblast differentiation and on GJIC measured by the fluorescence recovery after photobleaching method. We found that when the GJIC was interrupted, CT still aggregated but fused poorly. This morphological effect was associated with a significant decrease of trophoblastic-specific gene expression (β human chorionic gonadotropin and human chorionic somatomammotropin). This blocking action was reversible as demonstrated by recovery of GJIC and trophoblast differentiation process after heptanol removal. Moreover, the inhibition of the trophoblast differentiation did not affect Cx43 transcript expression and Cx43 protein expression. These data suggest that the molecular exchanges through gap junctions preceding cellular fusion are essential for trophoblast differentiation generating the multifunctional syncytiotrophoblast.
|
2022-12-19T09:33:38.269Z
|
255,219,859 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.26423/rcpi.v10i2.626",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBYNCSA",
"status": "GOLD",
"url": "https://incyt.upse.edu.ec/pedagogia/revistas/index.php/rcpi/article/download/626/564"
}
|
Las dinámicas de la sociedad en red ponen sobre la mesa la urgente necesidad por desarrollar competencias digitales, los maestros comprueban que las tecnologías digitales permean la enseñanza actual. Este articulo aborda la evolución de la noción sobre competencia digital docente, en la educación superior con énfasis en el modelo TPACK (Technological Pedagogical Content Knowledge), para aplicar conocimientos tecnológicos, pedagógicos y de contenido en la planeación de la práctica docente. El objetivo del estudio procura reducir la brecha digital de participantes del curso “Recursos análogos y digitales para la enseñanza” estructurado al Centro para el Aprendizaje, la Enseñanza y la Evaluación (CAE+E). La investigación presenta un enfoque mixto de corte descriptivo y agrupa a 71 maestros. Entre los resultados relevantes se evidencia la expresión del conocimiento pedagógico a partir de rangos experiencia profesional, como estrategias didácticas basadas en talleres, cátedras, y estudios de caso, como primordial propuesta pedagógica para actualizar la acción educativa. Como principal conclusión, se indica la pertinencia de concebir la competencia en el marco del proyecto Tuning con énfasis en el saber-hacer, como el uso de conocimientos pedagógicos y de contenido para planear la práctica docente contemporánea.
|
2022-12-30T18:29:55.931Z
|
150,462,363 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.30564/JLER.V2I1.331",
"MAG": "2940932857",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Owing to the negative view of Hong Kong English (HKE) in popular discourse, few English lecturers in Hong Kong universities directly acknowledge or discuss the variety in a non-linguistic course. This paper illustrates an action research study of how HKE may play a role in an academic writing course of a sub-degree program in Hong Kong. Focusing on 8 representatives from an academic writing course with 100 students, it employed the qualitative experiment method to examine whether students who had possessed basic linguistic knowledge of HKE from an additional tutorial would perceive HKE and academic writing differently from those who had not. Student representatives from each group were invited to a focus group to explore ideas about the two subjects discussed in class. Their conversations suggested that prior knowledge of the syntactic features of HKE might raise students’ awareness of the grammatical differences between the variety and the standard. The analysis also suggested that introducing the linguistic view of HKE to students might render them optimistic about their variety, helping them identify the situations where the variety would be tolerant of and settings where Standard English would be expected. The study suggested that such an intervention might facilitate students’ learning of Standard English for academic purposes and practices of English in actual professional communication. Upon the improvement or advancement, they will position themselves more powerfully in the dichotomy between the standard and non-standard. More formal research on a similar or relevant topic is required to validate the impact of understanding HKE on learning academic writing.
|
2022-02-09T03:50:22.689Z
|
80,273,505 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1136/ARCHDISCHILD-2018-RCPCH.181",
"MAG": "2791969780",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Aims Research and audit activity is mandatory for Paediatric trainees with one annual audit the minimum expected standard. Senior support has been shown to be helpful in facilitating successful project completion. With this aim a General Paediatric research workshop was established, providing a supportive forum for discussion and advice on individual projects. This paper will describe the development and outomes of this project. Methods An open, monthly, Consultant-supported, breakfast meeting was convened facilitating junior doctor attendance. Participants were allocated 5 min to provide a short focused presentation, noting progress and highlighting difficulties in research projects. Group input and structured feedback was encouraged to optimise ideas and solutions. Deadlines and targeted publications were advised with an aim to ensure project success. Attendances were recorded, weekly logs kept of each project with recommended advice and timelines for completion. Results 11 workshops have been held to date; involving Consultants, junior hospital doctors, Nurse Specialists, Dieticians and Physiotherapists. 17 projects have been submitted as presentations for the upcoming Irish Paediatric Association (IPA) Conference. In addition a further 10 projects are due for presentation at a variety of European Meetings in 2017, 1 project is now informing National UTI Guidelines and 1 project has been submitted for publication at a peer-reviewed Journal. In the year prior to the Research workshop initiative; 2 oral presentations and 9 (P) presentations were accepted at the IPA Conference. The feedback to date is overwhelmingly positive with Junior Doctors reporting greater support, interest and involvement in research. Conclusions The workshops continue and have expanded to include the General Paediatric Departments of Dublin’s 2 other Children’s Hospitals. The opening of Ireland’s new National Paediatric Hospital in 2022 will provide great opportunities for further development of the Academic Department of General Paediatrics. The goal is that this initiative will contribute to a structured template for further Research workshops across all Paediatric centres in Ireland and provide a collaborative Network for General Paediatric Research in the future.
|
2022-02-11T03:16:45.496Z
|
102,053,214 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1039/C6RA02232D",
"MAG": "2283141325",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Geopolymer monoliths with controlled lamellar macroporosity and total porosity ranging from 60% to 70% were prepared by ice-templating a partially geopolymerized slurry. Both the maturation treatment of the starting mixture and the water specifically added for freeze-casting were tailored to modify both the geopolymerization and viscosity of the slurry, and, consequently, its freezing behavior, in order to optimize the final lamellar architecture. Following a room temperature maturation treatment, a 50% water content added for freezing developed thick lamellae and wide pores. A lower water content (30%) and curing at 80 °C after maturation at room temperature (for both 50% and 30% H2O) was conducive to a narrow lamellar pore width distribution in the 30–130 μm range. However, the consumption of water due to geopolymerization in samples cured at 80 °C led to a decreased length and thickness of the lamellae. Lastly, the interparticle meso- and macropores (0.003 to 1 μm) within the geopolymer lamellae were only slightly modified by the maturation treatment.
|
2022-09-14T10:54:07.534Z
|
14,206,989 |
{
"externalids": {
"ACL": null,
"ArXiv": "math/0305394",
"DOI": "10.1112/S0010437X05001478",
"MAG": "2952442980",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We consider deformations of singular Lagrangian varieties in symplectic manifolds. We prove that a Lagrangian deformation of a Lagrangian complete intersection is analytically rigid provided that this is the case infinitesimally. This result is given as a consequence of the coherence of the direct image sheaves of relative infinitesimal Lagrangian deformations.
|
2022-09-16T03:41:21.362Z
|
219,500,993 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/0021998320927754",
"MAG": "3028371020",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
An indicator of being a strong country in today's world is that they have powerful weapons. In this sector where science is used exceedingly, the “stealth” takes an important place. Radar-absorbing materials are used in stealth technology to disguise an object from radar detection, such that it can allow a plane to be perceived as a bird. In this study, Co-doped zinc oxide reinforced styrofoam sheet composites were manufactured as radar-absorbing materials. For this purpose, Co-doped zinc–ZnO particles were synthesized via the Sol-Gel method with doping concentrations of 0%, 3%, 6%, 9%, and 12%. They were embedded in a styrofoam matrix with different loading levels to see the concentration dependence. The as-prepared powders were characterized by using X-ray diffraction and Scanning Electron Microscope-Energy Dispersive Spectroscopy. Magnetic characterization of samples was carried out using a vibrating sample magnetometer. Finally, the radar-absorbing test was applied with a network analyzer to achieve the main purpose of this research. It was concluded that Co-doped zinc oxide reinforced composites have electromagnetic properties that indicate potential applications in the radar-absorbing area.
|
2022-12-10T20:52:44.577Z
|
124,876,323 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1063/1.4954994",
"MAG": "2468488163",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The structure and various components of the electron drift velocity are discussed in application to plasma discharges with the E×B drift. In high density plasmas, the contribution of the diamagnetic drift can be of the same order magnitude as the E×B drift. It is pointed out that curvature and gradient drifts associated with magnetic field inhomogeneities manifest themselves via the electron pressure anisotropy. Estimates show that the components of the diamagnetic drift related to the electron pressure anisotropy and magnetic field gradients can be important for the parameters of modern magnetrons and Hall thrusters. Similar additional terms appear in the momentum balance as mirror forces which may affect the distribution of the electrostatic potential in Hall devices.
|
2022-12-16T10:07:58.235Z
|
119,306,827 |
{
"externalids": {
"ACL": null,
"ArXiv": "1712.00448",
"DOI": "10.1093/IMANUM/DRZ025",
"MAG": "2772859703",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We propose and analyse reliable and efficient a posteriori error estimators for an optimal control problem that involves a nondifferentiable cost functional, the Poisson problem as state equation and control constraints. To approximate the solution to the state and adjoint equations we consider a piecewise linear finite element method, whereas three different strategies are used to approximate the control variable: piecewise constant discretization, piecewise linear discretization and the so-called variational discretization approach. For the first two aforementioned solution techniques we devise an error estimator that can be decomposed as the sum of four contributions: two contributions that account for the discretization of the control variable and the associated subgradient and two contributions related to the discretization of the state and adjoint equations. The error estimator for the variational discretization approach is decomposed only in two contributions that are related to the discretization of the state and adjoint equations. On the basis of the devised a posteriori error estimators, we design simple adaptive strategies that yield optimal rates of convergence for the numerical examples that we perform.
|
2022-12-17T23:36:21.379Z
|
38,924,143 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.26719/2002.8.2-3.422",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://doi.org/10.26719/2002.8.2-3.422"
}
|
Community drug-use habits were studied in 469 household units in different areas of Sudan. About 97.7% of the investigated families had at least one drug product stored at home. The study revealed a high rate of self-medication (46.9%), repeated use of unfinished stored drugs (55.0%), a high rate of drug exchange among families (59.3%) and poor compliance (71.2%). In Sudan there is still a great need to educate and to motivate the general public regarding the principles of rational drug use in order to safeguard health and avoid economic losses.
|
2022-12-20T15:25:25.406Z
|
219,318,729 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.14309/ajg.0000000000000732",
"MAG": "3032053335",
"PubMedCentral": "7288768"
},
"license": "implied-oa",
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc7288768?pdf=render"
}
|
INTRODUCTION: Although coronavirus disease (COVID-19) has been associated with gastrointestinal manifestations, its effect on the pancreas remains unclear. We aimed to assess the frequency and characteristics of hyperlipasemia in patients with COVID-19. METHODS: A retrospective cohort study of hospitalized patients across 6 US centers with COVID-19. RESULTS: Of 71 patients, 9 (12.1%) developed hyperlipasemia, with 2 (2.8%) greater than 3 times upper limit of normal. No patient developed acute pancreatitis. Hyperlipasemia was not associated with poor outcomes or symptoms. DISCUSSION: Although a mild elevation in serum lipase was observed in some patients with COVID-19, clinical acute pancreatitis was not seen.
|
2022-12-21T11:14:42.819Z
|
2,974,389 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/TIT.2007.903116",
"MAG": "2124033592",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The problem of retrieving information by a mobile access point from a sensor network where sensors cooperatively transmit messages using a common codebook is considered. It is assumed that there is a probability that a sensor is misinformed with a wrong message, which complicates the information retrieval process. The access point uses the capacity achieving stay-k scheduler that schedules a sensor to transmit for k consecutive code-letters before switching to a new sensor. The random coding exponent is derived as a function of k, and it is shown that there is an optimal k that gives the largest error exponent. The application of low-definition parity-check (LDPC) codes is considered next. It is shown in simulations that the optimal k of the stay-k scheduler for LDPC codes can be inferred from that for the random coding exponent.
|
2022-12-31T18:50:02.136Z
|
234,650,213 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.24030/24092517-2020-0-3-149-159",
"MAG": "3134177728",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The history of intellectual/ideological directions presents sufficient interest for comprehension and interpretation on the part of other, competing and synchronous tendencies. The goal of the present article is to analyze Slavophilism interpretations and its place in the general process of Russian ideological and political directions development, proposed by the leading publicist of Russian populist camp in the years of 1870 – 1900. The intensity of Slavophil problems for the Populism (“Narodnichestvo”) was related to the evident and even stressed by some of the outside observers, connections of the key topics of populists and Slavophils, as well as obvious unpleasant by-products of accepting such intellectual continuity. The article shows how Mikhailovsky tried to minimize historiographically the connections and influence of Slavophils on the Populists, emphasizing at the same time the radical contradiction in understanding the notion of “people”, that was the key issue for both Slavophils and Populists. The interpretation of Slavophilism suggested by Mikhailovsky, especially its political and class significance, directly and indirectly influenced the subsequent historiography of Slavophilism. This aspect should be further studied, first of all in relation to the early Soviet historiography of Russian public thought.
|
2022-02-07T21:34:07.839Z
|
151,984,160 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.22437/JMPMIPA.V5I2.3390",
"MAG": "2590181578",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This research aimed to determine the effect of group investigation learning model and motivation on the students' learning result. The research employed a quasi experimental research with nonrandomized control group pretest-posttest design. The research used factorial design of 2x2. The population of this research was the first semester of seventh grade students. The sample used VII A and VII B class, samples were taken by using purposive sampling. The learning result data measured using of the tests and motivation data using of questionnaires. The data are analyzed using two-way(s) ANOVA. Test analysis showed that difference between post-test score of experiment class were higher than the control class. Based on the result, it can be concluded that: 1) the implementation of the group learning model investigation affect the students’ learning result, 2) motivation also influences the student learning result. 3) There is no interaction between the group investigation learning model and motivation on the students' learning achievement. Keywords: Group Investigation, Motivation and Learning Result.
|
2022-02-09T03:06:32.494Z
|
249,887,228 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/tropej/fmac050",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
BACKGROUND
Pneumonia acquired in the community is a leading cause of hospitalization and death in under-five children. Predicting mortality in children remains a challenge. There is a need of consolidated scoring system to predict mortality in under-five children in developing nations.
METHODS
This is a hospital-based prospective nested case-control study, conducted in a tertiary care teaching hospital of north India. Included were under-five hospitalized children due to WHO defined severe community acquired pneumonia (CAP). Those who did not survive were categorized as cases, while those who were discharged were categorized as controls.
RESULTS
The mortality rate among the recruited 180 hospitalized children with severe CAP was 9.4%. The mortality in under-five children was higher among infants, children who resided in rural areas and were unimmunized or partially immunized for the present age. Mortality was also statistically significantly higher among under-five children with weight for age and weight for length/height below -2Z score; SpO2 < 90% at room air at admission, cyanosis, convulsion, high C-reactive protein (CRP), blood culture positive sepsis and end point consolidation. These predictors were found to be independent risk factors for the mortality after analyzing in multivariate model while presence of wheeze and exclusive breast feeding for first six months of life were found to be protective. The receiver operating characteristic (ROC) curve for respiratory index of severity in children (RISC) score has area under curve (AUC) 0.91 while AUC of RISC score with King George's Medical University (KGMU) modification has 0.88 for prediction of mortality. At the cut-off level of 3, the sensitivity of the RISC score in predicting mortality was 94.1% while the specificity was 73.6%. However, the sensitivity of the RISC score with KGMU modification in predicting mortality at cut-off level of 3 was 88.4% with a specificity of 74.8%.
CONCLUSION
Various predictors for mortality under-five children are young age, malnutrition, cyanosis, high CRP, blood culture positive sepsis and end point consolidation. It is also possible to predict mortality using RISC score which comprises simple variables and can be easily used at centers of periphery. Similar accuracy had been also found through the use of an age independent modified score (RISC score with KGMU modification).Lay summaryPneumonia is a primary cause of hospitalization as well as death among the children under the age of five. A variety of severity or mortality predicting scores have been produced for adults, but such scores for children are scarce. Furthermore, their utility in developing nations has not been proven. This is a hospital-based prospective study. Included were children under five (2 to 59 months) hospitalized due to severe community acquired pneumonia (CAP) defined as per World Health Organization (WHO) and were not hospitalized in last 14 days elsewhere. Those who did not survive were classified as cases while those who were discharged were classified as controls. A total of 200 consecutively hospitalized children with severe CAP based on WHO were screened and 180 children were recruited. Among recruited children, the percentage of mortality was 9.4% while 90.6% were discharged. The mortality was higher among children younger than 12 months, those belonged to rural area and were unimmunized or partially immunized for the present age. Mortality was also higher among under-five children with severe malnutrition, anemia, SpO2 < 90% at room air at admission, cyanosis, convulsion, thrombocytopenia, high CRP, blood culture positive sepsis and end point consolidation. After assessing in a multivariate model, these predictors were determined to be independent risk factor for death, while wheezing and exclusive breast feeding throughout the first six months of life were found to be protective. The receiver operating characteristic (ROC) curve for respiratory index of severity in children (RISC) score has an area under curve (AUC) of 0.91 while AUC of RISC score with King George's Medical University (KGMU) modification was 0.88 for the prediction of death in under-five children hospitalized due to severe CAP.
|
2022-06-24T18:07:57.072Z
|
222,142,409 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3389/fpsyg.2020.02242",
"MAG": "3092329399",
"PubMedCentral": "7575867"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.frontiersin.org/articles/10.3389/fpsyg.2020.02242/pdf"
}
|
This article presents two studies that deepen the theme of how soundtracks shape our interpretation of audiovisuals. Embracing a multivariate perspective, Study 1 (N = 118) demonstrated, through an online between-subjects experiment, that two different music scores (melancholic vs. anxious) deeply affected the interpretations of an unknown movie scene in terms of empathy felt toward the main character, impressions of his personality, plot anticipations, and perception of the environment of the scene. With the melancholic music, participants felt empathy toward the character, viewing him as more agreeable and introverted, more oriented to memories than to decisions, while perceiving the environment as cozier. An almost opposite pattern emerged with the anxious music. In Study 2 (N = 92), we replicated the experiment in our lab but with the addition of eye-tracking and pupillometric measurements. Results of Study 1 were largely replicated; moreover, we proved that the anxious score, by increasing the participants’ vigilance and state of alert (wider pupil dilation), favored greater attention to minor details, as in the case of another character who was very hard to be noticed (more time spent on his figure). Results highlight the pervasive nature of the influence of music within the process of interpretation of visual scenes.
|
2022-12-18T07:58:41.005Z
|
6,494,646 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1331/154434503322612483",
"MAG": "149322140",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Opportunities abound for pharmacists to expand their practices by providing clinical services or assuring access to affordable pharmaceuticals to the medically underserved. The PSSC is a recently established resource at APhA that provides the pharmacy community and HRSA grantees with information and technical assistance on HRSA programs and projects. By participating in HRSA demonstration projections, pharmacists can implement much greatly needed patient care services to reduce disparities in health care. Becoming a 340B-contracted pharmacy can help pharmacists build prescription volume, expand their clinical services, and better serve the health care needs of their communities.
|
2022-09-21T17:24:11.259Z
|
222,462,631 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3760/CMA.J.ISSN.1007-1245.2018.19.034",
"MAG": "3032545797",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Objective
To investigate the effects of insulin secretagogues and acarbose on insulin resistance and levels of PAI-1 and GLP-1 in newly diagnosed type 2 diabetic patients.
Methods
A total of 160 newly diagnosed type 2 diabetic patients who were treated in our hospital from July 2015 to July 2017 were randomly divided into SG group, AG group, GG group, and RG group, who were treated with sitagliptin, acarbose, glibenclamide, and repaglinide respectively. The blood glucose biochemical indicators, insulin-related indicators, blood lipids, and serum GLP-1, GC, and PAI1 levels were compared among the four groups before and after treatment.
Results
There was no statistically significant difference in the efficacy of the four drugs (P>0.05). After treatment, 2 h INS in the four groups all significantly increased (P 0.05); the levels of TG [(2.04±0.54) mmol/L], TC [(4.64±0.67) mmol/L], and HDL-C [(2.57±0.43) mmol/L] in the SG group were significantly lower than those in the GG group and RG group (P 0.05).
Conclusion
Acarbose has an effect of raising the level of GLP-1, while insulin secretagogue has no significant effect on the level of GLP-1. Acarbose has the effect of regulating blood lipids and reducing PAI-1 level, which may be related to the remission of insulin resistance.
Key words:
Type 2 diabetes mellitus; Insulin secretagogue; Glucagon-like peptide-1; Plasminogen activator inhibitor 1
|
2022-02-08T00:51:31.566Z
|
143,940,866 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.6035/AGORASALUT.2015.1.18",
"MAG": "1973933636",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Introduction. In order to conduct a reliable assessment of psychological disorders, instruments with good psychometric properties must be developed. Specific phobias are highly prevalent and can become very disabling for many people (magee, Eaton, Wittchen, McGonable & Kessler, 1996). The aim of this study is to provide preliminary normative data of the Spider Phobia Beliefs Questionnaire (sBQ) (Arntz, Lavy, Van den Berg & Van Rijsoort, 1993) adapted for cockroach phobia in general and clinical Spanish population. method. The general sample was composed of 158 participants and the clinical sample included 63 patients. The sBQ is a questionnaire that is composed of two subscales, which assess beliefs related to spider phobia. It consists of 78 items describing situations related with the fear to these animals. The back translation process of the original version of the sBQ was conducted and the word spider was replaced by the word cockroach. Results. Internal consistency for both subscales in both populations showed an excellent Cronbach s alpha coefficient. In addition, there were significant differences in both subscales of the sBQ between the two groups. Conclusions. Preliminary results show that the Spanish version of the sBQ adaptation in this study has a good internal consistency for both subscales and in both populations. The adaptation of the sBQ was also effective in differentiating between clinical population diagnosed with cockroach phobia and general population.
|
2022-02-09T07:12:45.499Z
|
112,920,196 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1541/IEEJSMAS.120.392",
"MAG": "2312848061",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper deals with the driving principle and the experimental demonstration of a micro motor which can convert the rotation into the linear motion and generate the large displacement. The motor is a wobble type one; its rotor and stator have screw threads. When the rotor turns, it moves linearly in the axial direction like a screw. The range of the linear motion is limited only by the length of the rotor. We have fabricated a threaded wobble motor by the electro-magnetic actuation and operated it successfully.
|
2022-02-10T02:52:33.460Z
|
107,260,959 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.22260/ISARC2011/0287",
"MAG": "951163696",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Major sources of CO2 release caused by anthropogenic activities include fossil fuel combustion, cement production, and forest clear cut. The first two sources have been recognized as important in the construction industry; efforts have been made to find the causes of and the solutions to the emissions in the fuel combustion and cement production. However, the third major source–forest clear cut–has not yet received its deserving attention in the construction industry, although it may be one of the most important source of CO2 release in various infrastructure projects such as road construction. This study presents a methodology to calculate the amount of CO2 release from forest clear cut in a road construction project. An actual road construction in Korea was used as a case study for quantifying the CO2 release. First, the forest area was divided to three categories (biomass carbon stocks, carbon stocks in dead organic matters, and carbon stocks in soils) depending on the source of CO2 emission, as suggested by IPCC (International Panel on Climate Change). Second, for each category, a methodology was derived to estimate the CO2 emission amount using the gain-loss analysis. Finally, the CO2 emissions from the forest clear cut were compared to those from the fuel consumption by equipment usage in the same case to understand their relative magnitude in CO2 emissions. The study results are expected to be used as a basis for development of CO2 emission reduction strategies in road construction.
|
2022-02-25T00:11:52.145Z
|
117,845,469 |
{
"externalids": {
"ACL": null,
"ArXiv": "1410.6904",
"DOI": "10.1393/ncc/i2015-11858-9",
"MAG": "282466132",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A review is presented of the most recent measurements of top quark strong and electroweak production performed by using data collected with the ATLAS detector in proton-proton collisions at sqrt(s) = 7 and 8 TeV at the Large Hadron Collider corresponding to integrated luminosities of up to about 4.7/fb and 20/fb, respectively.
|
2022-03-04T21:58:06.810Z
|
134,720,462 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.19080/JFSCI.2017.02.555577",
"MAG": "2782518007",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
J Forensic Sci & Criminal Inves 2(1): JFSCI.MS.ID.555577 (2017) 001 Abstract Poaching is the act of illegal hunting of preserved and endangered wild species in the highly conserved areas and national parks. This trade is much rising in SADC countries due to demand of raw materials for industries in Asian continent. These countries make more demand of ivory and live animals for business. Forensic science can be the only way to help banning of this business all over Africa.
|
2022-06-13T11:18:43.039Z
|
98,137,869 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/MA00245A017",
"MAG": "2077778452",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Pyrogrammes de polyethylene lineaire, copolymeres ethylene-butene-1, ethylene-pentene-1 methyl-4, ethylene-octene-1 ethyl-4, ethylene-nonene-1 ethyl-5 et ethylene-butene-1-octene-1 ainsi que de polyethylene basse densite. L'hydrogenation des produits de pyrolyse avant chromatographie en phase gazeuse simplifie le chromatogramme et les produits sont plus faciles a identifier par spectrometrie de masse
|
2022-06-13T22:25:33.989Z
|
218,861,161 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/15563650500269799",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
8:00 am–5:00 pm AACT Pre-Meeting Symposium: The Handling of Radiation Emergencies Palazzo A–C Basic Principles in Health Physics Types of Radiation Exposure Dirty Bombs versus Nuclear Fission Clinical Effects of Radiation Exposure A Historical Overview of Radiation Accidents and Their Consequences Decontamination Principles: Differences between Chemical and Radiological Agents Radiologically Relevant Chelating Agents, Antidotes and Pharmaceuticals An Overview of Federal Preparedness Hospital Preparedness Guidelines Faculty: Doran Christensen, DO, REAC/TS Stephen Sugarman, MS, REAC/TS Robert Beauchamp, RN, NREMT-P, REAC/TS The participant at the end of this session should be able to: 1. Differentiate perceived versus actual clinical threats of the different types of radiation accidents. 2. Relate basic principles of health physics. 3. List the clinical consequences of radiation injury. 4. Describe events surrounding episodes of unintentional radiation exposure.
|
2022-07-09T11:51:40.533Z
|
17,452,376 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/MED.2016.7536050",
"MAG": "2510380710",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this article a Tilt-Wing Unmanned Aerial Vehicle (TW-UAV) and the preliminary evaluation of its hovering characteristics in extended simulation studies are presented. In the beginning, an overview of the TW-UAV's design properties are established, highlighting the novelties of the proposed structure and the overall merits. The TW-UAV's design and structural properties are mathematically modeled and utilized for the synthesis of a cascaded P-PI and PID based control structure for the regulation of its hovering performance. In addition, extensive simulation trials are performed in order to evaluate the structure's efficiency in controlling the TW-UAV's attitude and position under various noise and disturbance scenarios.
|
2022-12-10T06:06:21.044Z
|
40,403,552 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1365-2141.1994.tb04915.x",
"MAG": "2072321498",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
SUMMARY. Classic thrombotic thrombocytopenic purpura has substantial mortality and, because the pathogenesis is uncertain, multiple therapies are often used. These include corticosteroids and antiplatelet drugs, with plasma infusion or exchange most dramatically influencing outcome. To compare the relative efficacy of these latter two options, the records of 20 patients were retrospectively analysed. The groups were well matched for size and disease severity and received equivalent volumes of plasma. No significant difference in response rate or survival was demonstrated, although plasmapheresis may be preferable in the presence of impaired renal function with fluid overload.
|
2022-12-13T02:26:21.859Z
|
11,110,873 |
{
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"ArXiv": null,
"DOI": "10.1364/AO.51.003853",
"MAG": "2092894377",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We describe a methodology for determining the volume scattering function β(ψ) of aqueous particle suspensions from measurements with a laboratory multi-angle light scattering instrument called DAWN (Wyatt Technology Corporation). In addition to absolute and angular calibration, the key component of the method is the algorithm correcting for reflection errors that reduce the percent error in β(ψ) from as much as ~300% to <13% at backward scattering angles. The method is optimized and tested with simulations of three-dimensional radiative transfer of exact measurement geometry including the key components of the instrument and also validated experimentally using aqueous suspensions of polystyrene beads. Example applications of the method to samples of oceanic waters and comparisons of these measurements with results obtained with other light scattering instruments are presented.
|
2022-12-19T13:57:49.120Z
|
73,160,099 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/0968763032000159155",
"MAG": "2116627597",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract We explored the impact of drug misuse on sudden, unexpected, violent or unnatural male deaths, checking the association between official mortality statistics, health records, and coroner evidence and verdicts. We searched health and coroner records for all Merseyside and Cheshire coroner cases for men aged 15–39 in 1995, comparing our data with government mortality statistics. We explored the relationship between accidental/undetermined and suicide verdicts, and post-mortem drug and alcohol toxicity. Our survey included 238 cases; 221 had toxicological data and formed our final sample. There was post-mortem evidence of drugs in 90 cases, alcohol in 102, and both in 46. Overdose verdicts were given for 74 cases. We found evidence of significant alcohol problems in 18 cases and drug misuse in 74. The presence of drugs at post-mortem was significantly related to a verdict of accident/undetermined rather than suicide (p = 0.03). Post-mortem Class A drug toxicity was significantly related to accidental/undetermined verdicts compared to Class B/C drugs. There was no significant relationship between the number of drugs found and the verdict. While coroners determined drugs to be related to death in 90 cases, official classifications would have recorded this figure as 60 (ONS standard) or 40 (EMCDDA—European Union recommended classification). Our findings support the recommendations of the recent ACMD report into the reduction of drug-related deaths [1].
|
2022-02-11T09:19:31.725Z
|
131,706,128 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.13130/2039-4942/5889",
"MAG": "2202689935",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A new analysis of the most representative Upper Pleistocene (Tyrrhenian, MIS 5e) section of San Giovanni di Sinis (Oristano, Sardinia) has provided a more detailed genetic stratigraphy of a low wave energy beach and temperate lagoon up to emerged peri-lagoonal facies deposits. These peri-lagoonal facies contain remains of fossil vertebrates, which, though few and fragmentary, bear witness to an at least temporary freshwater palaeoenvironment and the presence of deers and terrapins. Besides, the stratigraphy of this outcrop shows shoreface-backshore sandstones overlaying an erosion surface cut on the vertebrate-bearing layers. Facies analysis and sequence stratigraphy of the succession have provided support to a new eustatic interpretation significance. In fact, there appears to be evidence of one irregular single eustatic highstand, rather than two eustatic peaks as previously believed. The facies evolution and the local stratigraphic disconformities are interpreted as being associated with a lateral shift of the depositional environment within the same system formed during the MIS 5e sea level variations. As sea water level continued to rise so an erosional unconformity, caused by wave ravinement, formed between the low wave energy beach-lagoon sequence and the successive wave dominated beach facies sequence. This interpretation is supported by comparison with other sections of the Tyrrhenian in western Sardinia. The maximum sea level attained during the Tyrrhenian stage is a clear indication of a warm-temperate climate which can be correlated to the well known orbital interglacial configuration when the eustatic signal of Greenland's ice sheet melting occurred. SHORT NOTES
|
2022-07-30T10:14:32.297Z
|
43,557,013 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1364/OE.24.023439",
"MAG": "2525147016",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The practical application of chaotic optical communications has been limited by two aspects: the difficulty in concealing the time delay - a critical security parameter in feedback chaotic systems, and the difficulty of significantly enlarging the key space without complicating the implementation. Here we propose an architecture to break the above limits. By introducing a frequency-dependent group delay module with frequency tuning resolution of 1 MHz into the chaotic feedback loop, we demonstrate excellent time delay concealment effect, and an additional huge key space of 1048 can be achieved at the same time. The effectiveness is proved by both numerical simulation and experiment. Besides, the proposed scheme is compatible with the existing commercial optical communication systems, thus pave the way for high-speed secure optical communications.
|
2022-12-21T19:46:32.161Z
|
86,892,830 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1270/JSBBS1951.6.117",
"MAG": "2321154207",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The writer studied the meiosis of three species hybrids in Nicotiana under the guidance of Dr. Y. TAKENAKA. The investigated hybrids were N. alata X N. Langsdorffii and the reciprocal, N. tabaculec X N. Lalegsdorffii and N. rustica X N. Lalegsdorffii. The external appearance of the hybrid N. alata (n =9) X N. Langsdorffii(n =9)corresponds well with descriptions given by other investigators. In about 78% of PMC's the chromosomes conjugated at MI as a rule to form 9 bivalents. Another chromosome configuration often observed was 7II+1IV (13%). Other configurations, such as 7II+1III+1I, 8II+2I, 6n+1IV+2I, 5II+2IV or 6II+2III, were also observed, each in less than 4% of PMC's.At AI one or two chromosome bridges were observed. The pollen produced appeared fairly normal and abundant seeds were obtained.
|
2022-02-10T22:00:33.179Z
|
210,262,665 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.20546/ijcmas.2019.810.044",
"MAG": "2985224110",
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://www.ijcmas.com/8-10-2019/Kusumlata Goswami, et al.pdf"
}
|
Agriculture is the mainstay of many developing economies, contributing significantly to GDP, food security, direct employment, export earnings and raw materials for other sectors (Kutywawo et al., 2012). With the world’s population continuing to rise, greater demands are being placed on our natural resources. The growing demand of population has resulted in an expansion of agriculture. There is a large probability that nutrients and sediment will be delivered to nearby surface waters from both urban and agricultural land. Krantz and Kifferstein (2005) have argued the importance of understanding water quality problems associated with land use effects, in order that we can be instrumental in helping solve these problems. This reinforces the notion of how critical it is to understand the effects of landbased developments on our rivers and lakes, in order to consider appropriate and sustainable management of these activities. International Journal of Current Microbiology and Applied Sciences ISSN: 2319-7706 Volume 8 Number 10 (2019) Journal homepage: http://www.ijcmas.com
|
2022-02-11T01:19:59.017Z
|
250,322,712 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.15388/teise.2022.123.3",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.journals.vu.lt/teise/article/download/28080/27350"
}
|
This article determines, based on legal norms, case law, and the scientific doctrine, the significance of legal customs in Lithuania in 1918–1940: it describes the legal customs in the status quo res erant ante bellum, i.e., in relation to which social groups and to what extent were the customs applied in Lithuania under the law of the Russian Empire. The significance of the constitutional provision on the reception of pre-war law for legal customs is revealed. The paper also describes the policy of the legislator with regard to legal customs, the limits of the application of customs by law, and the tendencies of legislation in this regard.
|
2022-07-11T02:22:02.009Z
|
250,735,371 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/0951-7715/9/5/010",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We study a new mechanism for the onset of chaos in coupled map lattices. The lattice dynamics becomes chaotic when the strength of spatial interactions exceeds some threshold. This transition is generated by the bifurcation that we call a peak-crossing one. It is shown that this mechanism can generate chaotic motion even in some coupled map lattices with extremely simple local dynamics. The resulting regime of chaos is characterized by space intermittency when the lattice is partitioned into alternating clusters that move chaotically and periodically, respectively.
|
2022-07-31T09:14:38.009Z
|
251,784,419 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/rs14164112",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2072-4292/14/16/4112/pdf?version=1661164962"
}
|
Continuous mapping of vegetation height is critical for many forestry applications, such as planning vegetation management in power transmission line right-of-way. Satellite images from different sensors, including SAR (Synthetic Aperture Radar) from Sentinel 1 (S1) and multispectral from Sentinel 2 (S2), can be used for producing high-resolution vegetation height maps at a broad scale. The main objective of this study is to assess the potential of S1 and S2 satellite data, both in a single and a multisensor approach, for modeling canopy height in a transmission line right-of-way located in the Atlantic Forest of Paraná, Brazil. For integrating S1 and S2 data, we used three machine learning algorithms (LR: Linear Regression, CART: Classification and Regression Trees, and RF: Random Forest) and airborne LiDAR (Light Detection and Ranging) measurements as the reference height. The best models were obtained using the RF algorithm and 20 m resolution features from only S2 data (cross-validated RMSE of 4.92 m and R2 of 0.58) or multisensor data (cross-validated RMSE of 4.86 m and R2 of 0.60). Although the multisensor model presented the best performance, it was not statistically different from the single-S2 model. Thus, the use of only S2 to estimate canopy height has practical advantages, as it reduces the need to process SAR images and the uncertainties due to S1 noise or differences between the acquisition dates of S2 and S1.
|
2022-10-14T13:22:20.113Z
|
20,222,946 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1109/ICSMC.2003.1244297",
"MAG": "1575257490",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Failure diagnosis in the context of DES was first formulated by Sampath et al. Where the notion of diagnosability and the associated diagnoser are proposed. Ushio et al. extended Sampath's study to systems modeled by Petri nets. This paper further assumes some of the transitions in a Petri net model are observable in the sense that its occurrence can be observed. The main contribution of this study shows how diagnosers and verifiers for systems modeled by Petri net are constructed accordingly. As shown by examples, the additional information from observed transitions adds diagnosability to the system.
|
2022-12-12T01:21:39.556Z
|
38,389,467 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/rcs.187",
"MAG": "1985385066",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
At present, the da Vinci® surgical robot system does not provide haptic feedback. One of the authors has proposed a contact‐force sensing method called the ‘overcoat method’, in which the instrument/driver is supported by force sensors. In the da Vinci robot, the instrument jaws are powered by a wire‐pulley mechanism; thus, in order to apply the overcoat method to the da Vinci system, we must transfer the power through a frame that is supported by force sensors.
|
2022-12-19T08:01:37.074Z
|
224,819,392 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/ijms21207698",
"MAG": "3092995827",
"PubMedCentral": "7589705"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/1422-0067/21/20/7698/pdf?version=1603010544"
}
|
Elevated concentration of homocysteine (Hcy) in the blood plasma, hyperhomocysteinemia (HHcy), has been implicated in various disorders, including cardiovascular and neurodegenerative diseases. Accumulating evidence indicates that pathophysiology of these diseases is linked with mitochondrial dysfunction. In this review, we discuss the current knowledge concerning the effects of HHcy on mitochondrial homeostasis, including energy metabolism, mitochondrial apoptotic pathway, and mitochondrial dynamics. The recent studies suggest that the interaction between Hcy and mitochondria is complex, and reactive oxygen species (ROS) are possible mediators of Hcy effects. We focus on mechanisms contributing to HHcy-associated oxidative stress, such as sources of ROS generation and alterations in antioxidant defense resulting from altered gene expression and post-translational modifications of proteins. Moreover, we discuss some recent findings suggesting that HHcy may have beneficial effects on mitochondrial ROS homeostasis and antioxidant defense. A better understanding of complex mechanisms through which Hcy affects mitochondrial functions could contribute to the development of more specific therapeutic strategies targeted at HHcy-associated disorders.
|
2022-12-28T19:13:50.116Z
|
241,597,433 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4018/978-1-7998-2645-3.ch004",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Membrane characterization is a critical necessity throughout the membrane's lifecycle. It mainly provides the connection between the fabrication and performance of the membrane. At the fabrication stage, membrane characterization allows us to study the membrane's characteristics in terms of its structure, morphology, chemical and physical properties, transport properties, etc. Membrane operation allows the determination of whether membrane cleaning is required or replacement is necessary. Finally, characterization at the end stage of membrane usability provides the causes of membrane failure which are significant data for future references. In that essence, this chapter discusses several methods that are used in membrane characterization processes, which are mainly categorized into the transport/flow, electron microscopy, scattering, and spectroscopy characterization methods.
|
2022-01-27T02:49:30.232Z
|
55,866,392 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.18517/IJASEIT.2.4.205",
"MAG": "1517891534",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Three different cultivation methods, i.e., shaking-flask culture (SFC), static surface liquid culture (SSLC) and membrane surface liquid culture (MSLC) were used to cultivate the filamentous fungi, Aspergillus niger PY11 in order to differentiate its behaviours by different cultivation methods using the same media, by determination of growth profile during fermentation. The dry cell weight, protein concentration, cellobiohydrolase (CBH) activity and residual sugar concentration in SSLC and MSLC were 1.5 to 2-folds than that by SFC. Cultivation of A. niger using MSLC was higher than SSLC with maximum biomass concentration, protein concentration and enzyme activity were 0.93 g dry weight/ml medium, 3.49 mg/ml and 36.99 U/ml respectively. MSLC possess the best growth characteristics and was the best cultivation method in production of CBH from A. niger PY11.
|
2022-07-31T10:51:59.310Z
|
239,845,735 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.14309/01.ajg.0000776232.82040.fa",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://journals.lww.com/ajg/Fulltext/2021/10001/S675_Mortality_and_Associated_Risk_Factors_After.676.aspx"
}
|
group. For secondary outcomes, patients with GIB had increased unadjusted odds for acute kidney injury (OR: 3.238, 95% CI: 2.387, 4.392, p, 0.001), vasopressor use (OR: 3.004, 95% CI: 2.242, 4.023, p, 0.001), and mechanical ventilation (OR: 2.806, 95% CI: 2.079, 3.787, p, 0.001). Conclusion: GIB is associated with increased odds for all-cause mortality, mechanical ventilation, vasopressor use, and acute kidney injury compared to patients without GIB. Despite having largely differing baseline characteristics, these findings support studies that suggest a correlation between GI symptoms and Covid-19 disease severity. Future research with a larger sample size is needed. Subsequently, supportive care is key to decreasing morbidity and mortality amongst these patients.
|
2022-03-19T02:51:56.060Z
|
125,960,051 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S0004972718000199",
"MAG": "2807420631",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In many physical systems noise plays a minor role, as a perturbation to deterministic motion; or a major role, in suppressing a deterministic signal. In this thesis we have considered a system in which noise plays a fundamental role in the observed dynamics. The particular system that we study consists of a nanowire that is suspended in a fluid, trapped by optical tweezers and subject to noise from collisions with the fluid particles. The motion of the nanowire is overdamped but experiments reveal a persistent cyclical motion. We have developed theoretical models, based on overdamped Langevin equations, which can accurately describe the observed behaviour of the nanowire. In these models the cyclical motion occurs as a result of coupling between the noise and the optical force, when the latter is nonconservative. The models may thus be used to probe the presence of nonconservative forces in optical tweezers experiments. The solutions of overdamped Langevin equations are single realisations of a stochastic trajectory of a particle in a fluid, subject to random fluctuations and a force field. The Fokker–Planck equation is an alternative formulation, whose solution describes the evolution of the probability density for the position of the particle. The Fokker–Planck equation can be derived from a microscopic description in terms of random walks. In order to consider more exotic fluids, including viscoelastic fluids, we have derived a fractional Fokker–Planck equation from a mesoscopic description involving continuous-time random walks with arbitrary initial conditions. Our derived model will facilitate the investigation of the motion of particles, such as nanowires, suspended in exotic fluids and trapped by optical tweezers. An intriguing aspect of the work in this thesis is that noise can play a constructive role in producing ordered behaviour.
|
2022-09-30T00:41:25.679Z
|
24,346,155 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1136/hrt.2010.200709",
"MAG": "2159176211",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Objectives To assess the quality of life (QoL) in adults with congenital heart disease (ACHD) and to explore the sex-related differences and biopsychosocial determinants in an Asian cohort. Design Prospective cross-sectional clinical study. Setting One tertiary medical centre in Taiwan. Patients and methods The QoL of ACHD (≥20 years) was investigated using the Taiwanese version of the QoL questionnaire designed by the WHO, which assesses four domains of QoL (physical, psychological, social and environmental). Personality, psychological distress and family support were assessed using the Maudsley Personality Inventory, Brief Symptom Rating Scale, and the Family APGAR score, respectively. Results A total of 289 patients (age 33.2±10.6 years; 36% men) were studied. ACHD women had significantly lower QoL scores in the physical and psychological domains compared to the age-matched general population, whereas no differences were observed between ACHD men and the general population. Multivariate analysis showed that female gender was associated with poorer physical QoL; the sex difference in the psychological QoL was mediated by psychological distress. Interaction analysis showed that the effect of family support on the psychological domain of QoL may be different by sex. The determinants of QoL varied between different domains. Extroversion personality trait, psychological distress and family support were common determinants of most domains of QoL. Conclusions In ACHD, female gender was associated with poor physical and psychological QoL. The common denominators for QoL were primarily personality trait, psychological distress and family support, but not disease severity.
|
2022-12-18T09:19:40.694Z
|
208,184,637 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/cbin.11263",
"MAG": "2991069615",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Alzheimer's disease (AD) is a chronic progressive neurodegenerative disorder. However, its pathogenetic mechanism is still poorly understood. An increasing number of studies have evidenced the important role of long noncoding RNAs (lncRNAs) in AD. The aim of the current study was to investigate the effect and molecular mechanism of the lncRNA X‐inactive specific transcript (XIST) in AD. Bilateral common carotid artery occlusion (2VO) was used to induce an AD model in mice. Hydrogen peroxide (H2O2) was used to induce an AD model in N2a cells. The lncRNA XIST, miR‐124, and BACE1 messenger RNA expression levels were detected by a real‐time polymerase chain reaction. The BACE1 protein expression level was detected by western blot and immunofluorescence assay. The Aβ1–42 expression level was detected using an enzyme‐linked immunosorbent assay kit. The expression level of lncRNA XIST was significantly upregulated in AD models, both in vivo and in vitro. Silencing of lncRNA XIST negatively regulated miR‐124 and positively regulated BACE1 expression in N2a cells, which is attenuated by cotransfection of anti‐miR‐124 oligodeoxyribonucleotide (AMO‐124). Silencing of lncRNA XIST reversed the effect of H2O2 on miR‐124, BACE1, and Aβ1–42 expression in N2a cells, which was reversed by cotransfection of AMO‐124. Silencing of lncRNA XIST attenuated AD‐related BACE1 alteration through miR‐124. LncRNA XIST may be a new potential target for the treatment of AD.
|
2022-12-24T14:54:03.455Z
|
181,064,114 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.7788/az-2006-0230",
"MAG": "2318807469",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Im Stollen eines ehemaligen Zinkbergwerks, beinahe 400 m tief im Innern des bekannten Schauinsland bei Freiburg im Südschwarzwald, überdeckt von einer 200 m dicken Schicht aus Gneis, abgeschlossen durch ein zehn Tonnen schweres Drucktor, lagern in hermetisch verschlossenen Behältern aus korrosionsfreiem V-4A-Stahl unter idealen mikroklimatischen Bedingungen hunderte Millionen Mikrofilmaufnahmen von Archivgut aus deutschen Archiven und ständig werden es mehr.1 Als vorbeugende Schutzmaßnahme im Rahmen der Haager Konvention zum Schutz von Kulturgut bei bewaffneten Konflikten aus dem Jahre 1954 soll die planmäßige Sicherungsverfilmung von Archivgut und die außergewöhnliche Art der Filmaufbewahrung gewährleisten, dass eine bildliche Ersatzüberlieferung von Archivgut auf äußerst stabilem Polyesterfilm auch unter denkbar ungünstigen Umständen künftigen Generationen erhalten wird.
|
2022-02-08T13:16:47.057Z
|
143,766,787 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.0022-2445.2005.00BR1.X-I1",
"MAG": "1987517944",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
At Play in Belfast. Donna M. Lanclos. New Brunswick, NJ: Rutgers University Press. 2003. 208 pp. ISBN 0-8135-3322-8. $21.95 (paper). Donna Lanclos provides an in-depth documentation of children's folklore and social identities based on her time on five playgrounds in Belfast. Lanclos spends time with children and provides us with their view in their words. She provides numerous examples of children's songs, rhymes, and games to illustrate her conclusions and bases her analysis within three broad categories of age, gender, and sectarianism. Lanclos does an excellent job with her ethnography, providing a detailed description of her data-gathering strategies and placing all analyses within a theoretical context. She describes the difficulties in watching children and gaining their trust as an adult. The first two chapters provide the reader with background on the research study and the children involved. The introduction is an overview of the study and a definition of folklore. She justifies extremely well the use of folklore studies to examine the lives of children. It also summarizes the research conducted on children in Northern Ireland and how this study compares. The author's initial assumptions are provided and how her views evolved throughout the process. Chapter 1 provides the reader with an overview of what the researcher's day was like and the general activities that the children were involved in during their time on the playgrounds. It grounds the reader and helps to place the remaining quotes and examples in the context of the overall day of the children. Many parents and teachers will recognize their own children's activities in the examples. Chapter 2 begins an analysis of the children's "rude" talk on the playgrounds and how children view the line between childhood and adulthood. Lanclos analyzes the societal view of an innocent childhood and how children construct a different set of values than the adults around them. She does an excellent job describing the children's view of "dirty" talk and placing it in context of what adults want and expect of children. Rather than assuming, as many adults do, that children do not know about dirty topics, Lanclos lets the children tell her what they know. This chapter also begins an exploration of the talk around violence in these children's lives. Chapter 3 focuses on how the children divide themselves into groups based on gender. As expected, gender is very important to the children, and many of the folklore rhymes focus on the roles of males and females. Lanclos's analysis of the children's games and rhymes provides a clear grounding that children all over are in some ways the same-boys and girls are different. She also emphasizes the particular societal culture that these children exist in and the apparent contradictions in their play and the adult world around them. …
|
2022-03-07T07:09:14.862Z
|
245,805,267 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.21203/rs.3.rs-1220217/v1",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GREEN",
"url": "https://www.researchsquare.com/article/rs-1220217/latest.pdf"
}
|
Ischemic stroke is a common and debilitating disease that can cause permanent neurological damage. Gucy1a3, which encodes the α1 subunit of soluble guanylyl cyclase, has been reported to be associated with functional recovery after ischemic stroke. However, the mechanism is still not well understood. In the present study, we investigated the effects of Gucy1a3 on (i) post-stroke recovery; (ii) vascular endothelial growth factor A (VEGFA) and hypoxia inducible factor 1 alpha (HIF-1α) expression; and (iii) angiogenesis after ischemic stroke. A permanent middle cerebral artery occlusion (pMCAO) model was established using wild-type and Gucy1a3 knockout C57BL/6J male mice. Neurological deficits, infarct volume, microvascular density, and VEGFA and HIF-1α expression levels of mice were evaluated. Our results suggest that loss of Gucy1a3 increased the infarct volume and aggravated neurological deficits after pMCAO. In addition, the Gucy1a3 knockout brains exhibited significantly lower microvessel densities and VEGFA and HIF-1α expression levels than the wild-type brains at 96 hours post-pMCAO. The study shows that the expression of GUCY1A3 after ischemic stroke may play a substantial role in neurological function recovery and is related to angiogenesis in the peri-infarct region. The beneficial effects of GUCY1A3 might be mediated through the HIF-1α/VEGFA signaling pathway.
|
2022-04-30T12:18:41.896Z
|
117,247,852 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/s0252921100089314",
"MAG": "48644289",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://www.cambridge.org/core/services/aop-cambridge-core/content/view/EAA734A043465A3B051022B5BE3C4CF4/S0252921100089314a.pdf/div-class-title-structure-of-comets-and-the-possible-origin-of-faint-asteroids-div.pdf"
}
|
It is shown that very old and still active icy-conglomerate or "clathrate" cometary nuclei may exist at the outer boundary of the asteroidal belt and belong to the group of relatively stable "outer" short-period comets of which only a small fraction have been discovered or recognized as cometary objects. The search for these comets among very faint asteroids with the mean motion H < 600", and the study of their behavior could be very important to our knowledge about the final stage of cometary nuclei.
|
2022-06-04T02:24:32.276Z
|
205,576,666 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/07391102.2016.1199329",
"MAG": "2410829633",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The molecular interactions of the sarcomeric proteins are essential in the regulation of various cardiac functions. Mutations in the gene MYBPC3 coding for cardiac myosin-binding protein-C (cMyBP-C), a multi-domain protein, are the most common cause of hypertrophic cardiomyopathy (HCM). The N-terminal complex, C1-motif-C2 is a central region in cMyBP-C for the regulation of cardiac muscle contraction. However, the mechanism of binding/unbinding of this complex during health and disease is unknown. Here, we study possible mechanisms of unbinding using steered molecular dynamics simulations for the complex in the wild type, in single mutations (E258K in C1, E441K in C2), as well as in a double mutation (E258K in C1 + E441K in C2), which are associated with severe HCM. The observed molecular events and the calculation of force utilized for the unbinding suggest the following: (i) double mutation can encourage the formation of rigid complex that required large amount of force and long-time to unbind, (ii) C1 appears to start to unbind ahead of C2 regardless of the mutation, and (iii) unbinding of C2 requires larger amount of force than C1. This molecular insight suggests that key HCM-causing mutations might significantly modify the native affinity required for the assembly of the domains in cMyBP-C, which is essential for normal cardiac function.
|
2022-09-06T01:45:50.642Z
|
40,718,449 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/ES011497V",
"MAG": "1987005562",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Magnetic resonance imaging (MRI) was used to determine the effects of pore-scale heterogeneity on the dissolution of a nonaqueous phase liquid (NAPL) in water-saturated flow-through columns (1.2 cm in diameter) packed with either approximately 500 or approximately 1,000 micron diameter angular silica gel (referred to as SG500 and SG1000, respectively). Columns were contaminated with 1,3,5-trifluorobenzene at residual saturation and then purged with water at a constant Darcy velocity of 1.83 m/day. Three-dimensional 19F images were acquired every 2-5 h at an imaging resolution of 59 x 234 x 234 microm3. Imaging results show that the specific NAPL surface area (a(t)) is linearly related to the NAPL volumetric fraction (theta(n)) and that the constant of proportionality between these parameters is determined by the blob size and geometry distribution. Overall (expressed as the modified Sherwood number, Sh') and intrinsic (expressed as the apparent Sherwood number, Sh(apt)) mass transfer rate coefficients were calculated. Values of Sh' and Sh(apt) for SG500 were approximately three times less than those for SG1000. For both solids, Sh' first increased or stayed the same and then decreased with decreasing theta(n), while Shapt generally increased with decreasing theta(n). These results suggest that during dissolution new flow paths were created (i.e., bypass zones were eliminated) as NAPL dissolved, decreasing the fraction of NAPL-water interfaces adjacent to pores filled with stagnant water and the average diffusion length scale. Since at for SG500 was dominated by less spherical multipore blobs (as opposed to more spherical singlets for SG1000), these results also suggest that the extent of flow bypassing (and the average diffusion length scale) increases in systems with more irregular blobs. These results are important because Sh' correlations and a "sphere" dissolution model do not account for transient changes in the fraction of NAPL surface area that contributes to dissolution or for the effect of initial blob size and geometry distribution on this fraction.
|
2022-12-02T09:06:24.112Z
|
38,557,479 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/ol8022648",
"MAG": "2051641739",
"PubMedCentral": null
},
"license": "CCBYNC",
"status": "GREEN",
"url": "https://figshare.com/articles/journal_contribution/Total_Synthesis_of_Lysergic_Acid_Lysergol_and_Isolysergol_by_Palladium_Catalyzed_Domino_Cyclization_of_Amino_Allenes_Bearing_a_Bromoindolyl_Group/2663242/1/files/4324660.pdf"
}
|
Ergot alkaloids and their synthetic analogs have been reported to exhibit broad biological activity. We investigated direct construction of the C/D ring system of ergot alkaloids based on palladium-catalyzed domino cyclization of amino allenes. With this biscyclization as the key step, total synthesis of (+/-)-lysergic acid, (+/-)-lysergol, and (+/-)-isolysergol was achieved.
|
2022-12-20T01:41:53.828Z
|
8,410,328 |
{
"externalids": {
"ACL": null,
"ArXiv": "astro-ph/0606646",
"DOI": "10.1051/0004-6361:20053679",
"MAG": "2130635487",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://www.aanda.org/articles/aa/pdf/2006/36/aa3679-05.pdf"
}
|
Aims. We study the synchrotron flaring behaviour of the blazar 3C 279 based on an extensive dataset covering 10 years of monitoring at 19 different frequencies in the radio-to-optical range. Methods. The properties of a typical outburst are derived from the observations by decomposing the 19 lightcurves into a series of self-similar events. This analysis is achieved by fitting all data simultaneously to a succession of outbursts defined according to the shock-in-jet model of Marscher & Gear (1985). Results. We compare the derived properties of the synchrotron outbursts in 3C 279 to those obtained with a similar method for the quasar 3C 273. It is argued that differences in the flaring behaviour of these two sources are intrinsic to the sources themselves rather than being due to orientation effects. We also compare the start times and flux densities of our modelled outbursts with those measured from radio components identified in Very Long Baseline Interferometry (VLBI) images. We find VLBI counterparts for most of our model outbursts, although some high-frequency peaking events are not seen in the radio maps. Finally, we study the link between the appearance of a new synchrotron component and the EGRET gamma-ray state of the source at 10 different epochs. We find that an early-stage shock component is always present during high gamma-ray states, while in low gamma-ray states the time since the onset of the last synchrotron outburst is significantly longer. This statistically significant correlation supports the idea that gamma-ray flares are associated with the early stages of shock components propagating in the jet. We note, however, that the shock wave is already beyond the broad line region during the gamma-ray flaring.
|
2022-12-17T13:02:36.986Z
|
15,848,635 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1126/science.aad0459",
"MAG": "2179298384",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The Mars Atmosphere and Volatile Evolution (MAVEN) mission, during the second of its Deep Dip campaigns, made comprehensive measurements of martian thermosphere and ionosphere composition, structure, and variability at altitudes down to ~130 kilometers in the subsolar region. This altitude range contains the diffusively separated upper atmosphere just above the well-mixed atmosphere, the layer of peak extreme ultraviolet heating and primary reservoir for atmospheric escape. In situ measurements of the upper atmosphere reveal previously unmeasured populations of neutral and charged particles, the homopause altitude at approximately 130 kilometers, and an unexpected level of variability both on an orbit-to-orbit basis and within individual orbits. These observations help constrain volatile escape processes controlled by thermosphere and ionosphere structure and variability.
|
2022-12-28T19:47:12.236Z
|
230,714,872 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.47023/ea.bilim.8527",
"MAG": "3111481093",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Bu yazimizda FOTON-M3 projesinin “Tardigrade Resistance to Space Effects” (TARSE) misyonu yani "Uzay Etkilerine Tardigrad Direnci" misyonu uzerinde durulup ilk deney sonuclarina dair bilgiler verilmeye calisilmistir. FOTON-M3 projesinin diger misyonlari olan TARDIS misyonuna ait yazimiza buradan, RoTaRad misyonuna ait yazimiza ise buradan ulasabilirsiniz.FOTON-M3 projesi nedir?Foton, Rus bilim uydu ve yeniden giris araci programlarinin proje adidir. Foton projesinin ana odagi ise genel anlamda malzeme
|
2022-02-07T22:31:59.926Z
|
55,241,318 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1049/CP:20051225",
"MAG": "1990462075",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The requirements for improvement in the stability of electric power systems and reduction in the effect of short circuit faults or other abnormal system conditions on sensitive customers can be met only by optimised configuration of the different protection and control systems at the transmission and distribution system level. The definition of requirements for protective relays performance, the possibility for adaptive protection applications in case of dynamic changes in the system configuration and the need for special remedial action protection systems are based on the use of advanced analysis tools. They model the primary and secondary components of electric power systems and analyse its operation under normal or abnormal conditions. The accuracy of the different simulations is determined to a great extent by the accuracy of the models. The paper describes different types of protection related analysis tools: • Short Circuit and Protection Co-ordination • Dynamic Stability • Electromagnetic Transients The models of power system equipment and the requirements for verification of these models in the different types of software are discussed later in the paper. The wide spread use of distributed generation in distribution systems introduces a new level of complexity of the modelling. This is due to the fact that the different types of distributed resources (Reciprocating Diesel or Natural Gas Engines, Microturbines, Combustion Gas Turbines, Fuel Cells, Photovoltaics (PV) and Wind Turbines) have different behaviour under different abnormal conditions. The recording capabilities of multifunctional IEDs are described and different recording modes are identified and proposed for specific needs. The architecture of a distributed system for recording system disturbances is presented. Requirements for time synchronisation of multifunctional IED located throughout the system are discussed.
|
2022-02-11T20:08:13.687Z
|
246,525,710 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3846/tede.2022.16284",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
This paper estimates the social welfare effect of China’s largest online ride-sharing platform. Under the plausible assumption that consumers would change from traditional transportation to online ride-sharing when the marginal benefit of saved time outgrows the additional cost, we calculate the distribution of implied wage rate of passengers. We then use the passenger wage rate to calculate the social welfare generated by the decrease in waiting time and the reduction of waiting uncertainty brought about by the ride-sharing platform. Our estimate suggests that the ride-sharing platform created a total of 130.5 billion Yuan of social welfare in the three years between 2016 and 2018, and the consumer surplus and producer surplus created by an average transaction are 5.4 Yuan and 2.5 Yuan, respectively. The robustness test finds that our results were insensitive to the assumed risk aversion coefficient in the model, the subsample number used for each city, and the inclusion of nonlinear terms in the model. Alternative hypotheses, such as learning effect, seem unable to explain our result.
|
2022-08-20T02:11:24.170Z
|
100,241,403 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/0954-0083/5/1/007",
"MAG": "2515568762",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A general method for the preparation of oxadiazole containing aromatic poly(ether ketone)s has been developed. Polymerization is based on a ketone-activated halo displacement in oxadiazole containing bis(4-fluorobenzoyl) moieties by phenoxides. 2,5-bis[4-(4-fluorobenzoyl-(4-phenoxyphenyl)]-1,3,4-oxadiazole was prepared by reaction of 4-fluorobenzoyl chloride with 2,5-bis(4-phenoxyphenyl)-1,3,4-oxadiazole in dichloromethane in the presence of aluminium chloride. Reaction of 2,5-bis[4-(4-fiuorobenzoyl)-(4-phenoxyphenyl)]-1,3,4-oxadiazole with diphenols in an aprotic solvent in the presence of potassium carbonate gave a series of aromatic poly(ether ketone oxadiazole)s. Films of the aromatic poly(ether ketone oxadiazole)s displayed good thermal stability, flexibility, and Ts s ranging from 172 to 218 C. The dielectric constants of the films were characterized as a function of relative humidity (RH).
|
2022-09-03T17:46:33.517Z
|
40,955,972 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3109/10641968609046597",
"MAG": "2222721376",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Weight loss, polydipsia, polyuria, hyponatremia are symptoms often seen in patients with severe renin-induced hypertension. To investigate the role of the maturing kidney in the development of high pressure diuresis hypertension was induced in infantile (18 days old) and adult (40 days old) Sprague-Dawley rats by clipping one renal artery. In infantile rats blood pressure increase was steeper than in adult rats (7.8 vs. 3.2 mmHg/day). High pressure diuresis resulting in body weight loss was observed at systolic blood pressure levels of about 140 to 150 mmHg in infantile animals compared to 180 mmHg in adult rats. At this time fluid intake was increased to 64 in infantile and 30 ml/100 g body weight/day in adult rats. Plasma renin concentration and aldosterone were two fold higher in infantile than in adult rats. The data show that infantile rats, due to a higher activation of the renin-angiotensin-aldosterone system, have a steeper blood pressure increase and, furthermore, that during maturation of the kidney high pressure diuresis starts at lower blood pressure levels and is much more pronounced.
|
2022-09-06T06:59:21.295Z
|
216,533,651 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.46367/JPS.V1I1.205",
"MAG": "3012883352",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This research aims to find out how the SWOT analysis as a strategy to improve competitiveness and obstacles in the Bank of Riau Kepri, Pekanbaru Business Unit. The research method used is quantitative descriptive method. The SWOT analysis used is descriptive analysis methods, SWOT matrix and SWOT diagram analysis. Data collection techniques in this study were interviews, questionnaires and literature. The results of this study are the SWOT analysis as a strategy to increase competitiveness needs to be evaluated again so that the formation of good performance from within and from outside the Bank of Riau Kepri, Pekanbaru Sharia Business Unit in advancing these banks throughout Province of Riau and Riau Islands.
|
2022-11-18T00:18:03.819Z
|
40,552,609 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S0016672300016414",
"MAG": "2156696920",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Destruction by laser microbeam of oral and ventral cirral primordia for the future opisthe of 1/2 of a pre-fission doublet results in the permanent loss of ability to form oral and ventral cirral primordia on the irradiated half. This observation provides further evidence for the postulated ‘determinative region’ present on each ventral surface of these organisms. The opisthe of the irradiated doublet retains both original rows of marginal cirri, which are located mid-dorsally with respect to the remaining ventral surface. These two rows of marginal cirri are reproduced faithfully in all future opisthes, but are lost in most proter lines. The pattern of loss in proters involves migration of the extra rows of marginal cirri to the cell's right margin followed by aberrant morphogenesis and subsequent resorption. These results show that the reproduction of marginal cirri is at least partially dependent upon the presence of marginal cirri and their inherent structural characteristics as well as upon their position on the cell surface.
|
2022-12-11T13:29:49.623Z
|
45,874,993 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/SLA.0000000000000841",
"MAG": "2009806936",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
OBJECTIVE(S)
The monopolar "Bovie" is used in virtually every laparoscopic operation. The active electrode and its cord emit radiofrequency energy that couples (or transfers) to nearby conductive material without direct contact. This phenomenon is increased when the active electrode cord is oriented parallel to another wire/cord. The parallel orientation of the "Bovie" and laparoscopic camera cords cause transfer of energy to the camera cord resulting in cutaneous burns at the camera trocar incision. We hypothesized that separating the active electrode/camera cords would reduce thermal injury occurring at the camera trocar incision in comparison to parallel oriented active electrode/camera cords.
METHODS
In this prospective, blinded, randomized controlled trial, patients undergoing standardized laparoscopic cholecystectomy were randomized to separated active electrode/camera cords or parallel oriented active electrode/camera cords. The primary outcome variable was thermal injury determined by histology from skin biopsied at the camera trocar incision.
RESULTS
Eighty-four patients participated. Baseline demographics were similar in the groups for age, sex, preoperative diagnosis, operative time, and blood loss. Thermal injury at the camera trocar incision was lower in the separated versus parallel group (31% vs 57%; P = 0.027).
CONCLUSIONS
Separation of the laparoscopic camera cord from the active electrode cord decreases thermal injury from antenna coupling at the camera trocar incision in comparison to the parallel orientation of these cords. Therefore, parallel orientation of these cords (an arrangement promoted by integrated operating rooms) should be abandoned. The findings of this study should influence the operating room setup for all laparoscopic cases.
|
2022-12-12T23:11:47.350Z
|
17,160,900 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1152/JN.01025.2006",
"MAG": "2036932350",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The purpose of this study was to determine the factors that influence the co-modulation of motor unit discharge rate in soleus muscles of both legs during upright standing. Single motor units were recorded from the left and right soleus muscles under three experimental conditions: standing quietly with the eyes open and closed, standing with the eyes closed while vibration was applied to one Achilles tendon, and swaying voluntarily or producing variable low-force isometric contractions at a frequency of 0.05 Hz. Correlations in motor unit discharge rate between left and right soleus motor units were assessed using common drive analysis. The results showed that common drive to motoneurons of the two muscles did not differ between standing with the eyes open or closed, but there was an order effect with the second task having significantly lower common drive than the first. Common drive was also significantly lower when vibration was applied to one leg compared with when no vibration was applied. Common drive was higher as subjects swayed anteriorly as compared with when they swayed posteriorly. There were no significant differences in common drive across phases of the variable isometric force contraction. Common drive was higher during voluntary sway than during variable force production; both of these values were significantly lower than those derived from the quiet standing task. These results suggest that proprioceptive and sub-cortical inputs contribute to the co-modulation of the firing rate of soleus motor unit pairs of the left and right leg during standing posture.
|
2022-12-18T14:35:16.356Z
|
16,964,012 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2202/1941-1928.1074",
"MAG": "1987308187",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "http://www.stats.bris.ac.uk/%7Eguy/Research/papers/Costationary2.pdf"
}
|
Given more than one locally stationary (LS) time series, this article describes a method to discover time-varying linear combinations of the LS series that are stationary. Systems for which this can occur are called costationary, and the associated time-varying linear combinations are called costationary vectors. Costationary systems are interesting for a number of reasons. The costationary vectors shed light on the nature and strength of a potentially interesting relationship between the LS series. The derived stationary series, which is the time-varying combination of the LS series, is often of independent interest and use. The article discusses why a spectral approach is often preferred to the time-domain and why costationary vectors need to be complexity constrained, and it also demonstrates an interesting error-correction formulae which shows how costationary systems must evolve to maintain stationarity in response to system shocks. We illustrate our methodology with two examples: one from asset allocation in financial portfolio construction and the other which mitigates intermittency in wind power management. In the former, a stationary synthetic asset is constructed using market index data and is shown to have superior Sharpe ratios to two established portfolio selectors. In the latter, power outputs from separate wind series are dynamically combined to provide a power output which has smaller intermittency than the individual inputs.
|
2022-12-26T06:11:20.724Z
|
128,044,258 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/0049124119826154",
"MAG": "2916853554",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Log-linear models for contingency tables are a key tool for the study of categorical inequalities in sociology. However, the conventional approach to model selection and specification suffers from at least two limitations: reliance on oftentimes equivocal diagnostics yielded by fit statistics, and the inability to identify patterns of association not covered by model candidates. In this article, we propose an application of Lasso regularization that addresses the aforementioned limitations. We evaluate our method through a Monte Carlo experiment and an empirical study of educational assortative mating in Chile, 1990–2015. Results demonstrate that our approach has the virtue, relative to ad hoc specification searches, of offering a principled statistical criterion to inductively select a model. Importantly, we show that in situations where conventional fit statistics provide conflicting diagnostics, our Lasso-based approach is consistent in its model choice, yielding solutions that are both predictive and parsimonious.
|
2022-12-29T13:42:03.009Z
|
2,856,789 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4103/0250-474X.51958",
"MAG": "2083269287",
"PubMedCentral": "2810061"
},
"license": null,
"status": null,
"url": null
}
|
Solubility enhancement of antimicrobial drug enrofloxacin has been studied using a series of co-solvents and surfactants. Aqueous solubility of enrofloxacin could be increased up to 26 times. Co-solvents alone produced only small increase in solubility. However, the combined effect of co-solvents and buffer was synergistic and a large increase in solubility could be attained. Ionic surfactants were found to be much better solubilizing agents than non-ionic surfactant. Amongst ionic surfactants, solubility was found to be very high in anionic surfactant, sodium dodecylsulphate as compared to the cationic surfactant, cetyltrimethylammonium bromide. Up to 3.8 mg/ml of enrofloxacin could be dissolved in sodium dodecylsulphate. Mechanism of solubilization has been proposed and surfactant solubilization parameters have been calculated.
|
2022-12-29T17:15:13.846Z
|