donb-hf/secondary-screen-dose-response-curve-parameters

broad_id string	depmap_id string	ccle_name string	screen_id string	upper_limit int64	lower_limit float64	slope float64	r2 float64	auc float64	ec50 float64	ic50 float64	name string	moa string	target string	disease.area string	indication string	smiles string	phase string	passed_str_profiling bool	row_name string
BRD-K47832606-001-30-1	ACH-000663	OVTOKO_OVARY	HTS002	1	0.219316	8.515367	0.612144	0.636947	0.109674	0.117368	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000663
BRD-K47832606-001-30-1	ACH-000647	TE1_OESOPHAGUS	HTS002	1	0.230715	1.747896	0.672697	0.607636	0.070871	0.100979	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000647
BRD-K47832606-001-30-1	ACH-000243	DANG_PANCREAS	HTS002	1	0.284159	4.281361	0.640799	0.612532	0.052339	0.063686	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000243
BRD-K47832606-001-30-1	ACH-000255	LMSU_STOMACH	HTS002	1	0.033488	11.078989	0.84709	0.54994	0.109027	0.109712	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000255
BRD-K47832606-001-30-1	ACH-000335	MSTO211H_PLEURA	HTS002	1	0.067022	10.860529	0.800652	0.451965	0.033452	0.033899	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000335
BRD-K47832606-001-30-1	ACH-000147	T47D_BREAST	HTS002	1	0.266885	2.834215	0.636041	0.576143	0.036592	0.047898	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000147
BRD-K47832606-001-30-1	ACH-000090	PC3_PROSTATE	HTS002	1	0.097811	0.844409	0.814521	0.483654	0.037759	0.048863	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000090
BRD-K47832606-001-30-1	ACH-000171	VMRCRCZ_KIDNEY	HTS002	1	0.67773	3.780734	0.021568	0.862028	0.156925	null	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000171
BRD-K47832606-001-30-1	ACH-000614	RVH421_SKIN	HTS002	1	0.300601	1.302141	0.658963	0.631791	0.060373	0.122306	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000614
BRD-K47832606-001-30-1	ACH-000132	JHOS2_OVARY	HTS002	1	0.254363	12.338974	0.686919	0.63132	0.082447	0.087336	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000132
BRD-K47832606-001-30-1	ACH-000274	HS852T_SKIN	HTS002	1	0.271823	1.238714	0.129492	0.729425	0.274079	0.516319	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000274
BRD-K47832606-001-30-1	null	null	HTS002	1	0.179773	2.517844	0.760872	0.623013	0.11561	0.137991	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	false	ACH-000807_FAILED_STR
BRD-K47832606-001-30-1	ACH-000810	SKMEL30_SKIN	HTS002	1	0.395335	4.163172	0.414604	0.729584	0.130389	0.189836	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000810
BRD-K47832606-001-30-1	ACH-000343	NCIH522_LUNG	HTS002	1	0.354323	3.674071	0.356496	0.703065	0.115308	0.161299	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000343
BRD-K47832606-001-30-1	ACH-000022	PATU8988S_PANCREAS	HTS002	1	0.668989	2.629579	-0.058998	0.796441	0.025602	null	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000022
BRD-K47832606-001-30-1	ACH-000192	MFE280_ENDOMETRIUM	HTS002	1	0.192636	2.189467	0.595645	0.589738	0.072184	0.090148	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000192
BRD-K47832606-001-30-1	null	null	HTS002	1	0.228342	3.112621	0.721031	0.569541	0.04457	0.05422	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	false	ACH-000409_FAILED_STR
BRD-K47832606-001-30-1	ACH-000959	SNUC4_LARGE_INTESTINE	HTS002	1	0.128105	3.962022	0.802776	0.358158	0.007899	0.008512	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000959
BRD-K47832606-001-30-1	null	null	HTS002	1	0.322935	2.704883	0.915784	0.602132	0.033377	0.048991	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	false	ACH-000028_FAILED_STR
BRD-K47832606-001-30-1	ACH-000637	KYSE520_OESOPHAGUS	HTS002	1	0.228877	1.215429	0.702417	0.65952	0.138242	0.228734	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000637
BRD-K47832606-001-30-1	ACH-000968	COLO792_SKIN	HTS002	1	0.342563	4.328023	0.380967	0.715473	0.149994	0.195898	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000968
BRD-K47832606-001-30-1	ACH-000155	SW1990_PANCREAS	HTS002	1	0.214757	1.930037	0.842483	0.591478	0.064185	0.085848	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000155
BRD-K47832606-001-30-1	ACH-000133	HS729_SOFT_TISSUE	HTS002	1	0.123818	2.503209	0.673605	0.519727	0.048965	0.05486	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000133
BRD-K47832606-001-30-1	ACH-000605	TE6_OESOPHAGUS	HTS002	1	0.247221	2.059205	0.754324	0.558556	0.03377	0.047031	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000605
BRD-K47832606-001-30-1	ACH-000775	NCIH727_LUNG	HTS002	1	1.340129	-6.886617	0.305596	1.168191	0.074058	null	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000775
BRD-K47832606-001-30-1	ACH-000042	PANC0203_PANCREAS	HTS002	1	0.292173	2.262436	0.565339	0.588604	0.035523	0.052364	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000042
BRD-K47832606-001-30-1	ACH-000860	NCIH358_LUNG	HTS002	1	0.375951	5.522596	0.760798	0.706897	0.104851	0.134956	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000860
BRD-K47832606-001-30-1	ACH-000994	HEC59_ENDOMETRIUM	HTS002	1	0.107773	0.807705	0.68558	0.651699	0.237732	0.321086	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000994
BRD-K47832606-001-30-1	ACH-000277	HCC1419_BREAST	HTS002	1	0.402657	5.472122	0.539262	0.726524	0.117639	0.158643	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000277
BRD-K47832606-001-30-1	ACH-000496	NCIH1792_LUNG	HTS002	1	0.170276	2.522395	0.415104	0.586879	0.079732	0.094041	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000496
BRD-K47832606-001-30-1	ACH-000866	NCIH1048_LUNG	HTS002	1	0.057024	1.36146	0.811312	0.385988	0.017893	0.019557	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000866
BRD-K47832606-001-30-1	ACH-000869	NCIH1568_LUNG	HTS002	1	0.168328	3.38637	0.66567	0.516826	0.035609	0.040197	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000869
BRD-K47832606-001-30-1	ACH-000117	EFM192A_BREAST	HTS002	1	0.467316	1.752502	0.269928	0.769721	0.150749	0.714856	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000117
BRD-K47832606-001-30-1	ACH-000678	MKN7_STOMACH	HTS002	1	0.344349	2.341931	0.572858	0.634767	0.044909	0.073917	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000678
BRD-K47832606-001-30-1	ACH-000493	SNU423_LIVER	HTS002	1	0.102317	1.12875	0.714851	0.480335	0.036068	0.044179	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000493
BRD-K47832606-001-30-1	ACH-000468	PK45H_PANCREAS	HTS002	1	0.509025	1.601809	0.417446	0.793847	0.170132	null	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000468
BRD-K47832606-001-30-1	ACH-000097	ZR751_BREAST	HTS002	1	0.156175	1.389226	0.685561	0.695568	0.303319	0.397161	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000097
BRD-K47832606-001-30-1	ACH-000313	KMRC3_KIDNEY	HTS002	1	0.2122	1.311834	0.760344	0.593288	0.066682	0.101594	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000313
BRD-K47832606-001-30-1	ACH-000169	RD_SOFT_TISSUE	HTS002	1	0.043979	0.976793	0.569177	0.538843	0.092982	0.102172	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000169
BRD-K47832606-001-30-1	null	null	HTS002	1	0.153958	4.204517	0.76929	0.496968	0.031205	0.03406	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	false	ACH-000010_FAILED_STR
BRD-K47832606-001-30-1	ACH-000895	CL34_LARGE_INTESTINE	HTS002	1	0.180361	6.295257	0.355604	0.554725	0.051343	0.055125	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000895
BRD-K47832606-001-30-1	ACH-000841	NCIH2087_LUNG	HTS002	1	0.176174	2.567031	0.692966	0.588456	0.078464	0.092932	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000841
BRD-K47832606-001-30-1	ACH-000414	NCIH1944_LUNG	HTS002	1	0.049855	9.144912	0.788346	0.464332	0.042074	0.04256	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000414
BRD-K47832606-001-30-1	ACH-000026	253JBV_URINARY_TRACT	HTS002	1	0.179625	1.388001	0.649139	0.707212	0.315066	0.434186	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000026
BRD-K47832606-001-30-1	ACH-000649	786O_KIDNEY	HTS002	1	0.211157	11.675057	0.748381	0.605516	0.078065	0.081821	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000649
BRD-K47832606-001-30-1	ACH-000966	IGROV1_OVARY	HTS002	1	0.17933	2.42986	0.824199	0.604089	0.092653	0.111238	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000966
BRD-K47832606-001-30-1	ACH-000950	LOVO_LARGE_INTESTINE	HTS002	1	0.153047	3.645718	0.7834	0.497731	0.031675	0.035014	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000950
BRD-K47832606-001-30-1	ACH-000750	LOXIMVI_SKIN	HTS002	1	0.333666	8.296873	0.51667	0.678583	0.092706	0.105856	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000750
BRD-K47832606-001-30-1	ACH-000958	SW48_LARGE_INTESTINE	HTS002	1	0.266774	0.503806	-0.093518	0.537133	0.01677	0.076195	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000958
BRD-K47832606-001-30-1	ACH-000270	HPAC_PANCREAS	HTS002	1	0.329027	2.058033	0.463504	0.613063	0.037117	0.062521	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000270
BRD-K47832606-001-30-1	ACH-000535	BXPC3_PANCREAS	HTS002	1	1.263033	-0.680512	0.021593	1.069793	0.006128	null	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000535
BRD-K47832606-001-30-1	ACH-000480	HUH7_LIVER	HTS002	1	1.381123	-0.059533	0.000364	1.230998	114.292282	null	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000480
BRD-K47832606-001-30-1	ACH-000281	KP2_PANCREAS	HTS002	1	1.386105	-5.223036	0.289613	1.176107	0.05103	null	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000281
BRD-K47832606-001-30-1	ACH-000897	FTC238_THYROID	HTS002	1	0.152916	6.311568	0.442876	0.608675	0.112999	0.119727	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000897
BRD-K47832606-001-30-1	ACH-000389	H4_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.374167	1.898738	0.39534	0.639504	0.03735	0.077243	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000389
BRD-K47832606-001-30-1	ACH-000862	KMBC2_URINARY_TRACT	HTS002	1	0.159287	5.304975	0.913682	0.508549	0.034387	0.036965	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000862
BRD-K47832606-001-30-1	ACH-000776	ONS76_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.250975	1.436514	0.79145	0.575295	0.040716	0.066146	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000776
BRD-K47832606-001-30-1	ACH-000023	PATU8988T_PANCREAS	HTS002	1	0.157098	2.568904	0.958449	0.553352	0.058452	0.067696	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000023
BRD-K47832606-001-30-1	ACH-000011	253J_URINARY_TRACT	HTS002	1	0.192388	2.218039	0.829035	0.591061	0.073451	0.091435	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000011
BRD-K47832606-001-30-1	ACH-000973	639V_URINARY_TRACT	HTS002	1	0.053086	4.674771	0.926368	0.299903	0.007657	0.007843	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000973
BRD-K47832606-001-30-1	ACH-001024	CHL1_SKIN	HTS002	1	0.195194	1.992654	0.667592	0.590995	0.072146	0.092487	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-001024
BRD-K47832606-001-30-1	ACH-000971	HCT116_LARGE_INTESTINE	HTS002	1	0.20295	1.861161	0.850531	0.610653	0.087363	0.115566	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000971
BRD-K47832606-001-30-1	ACH-000486	KU1919_URINARY_TRACT	HTS002	1	0.108403	2.444954	0.866664	0.449017	0.024864	0.027478	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000486
BRD-K47832606-001-30-1	ACH-000997	HCT15_LARGE_INTESTINE	HTS002	1	0.083699	3.920667	0.704994	0.492596	0.046371	0.048589	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000997
BRD-K47832606-001-30-1	ACH-000552	HT29_LARGE_INTESTINE	HTS002	1	0.157672	2.410343	0.720447	0.465697	0.021217	0.024828	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000552
BRD-K47832606-001-30-1	ACH-000796	MCAS_OVARY	HTS002	1	0.225379	2.652252	0.825676	0.615566	0.080991	0.101521	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000796
BRD-K47832606-001-30-1	ACH-000652	SUIT2_PANCREAS	HTS002	1	0.314497	1.637776	0.696319	0.646922	0.067492	0.123646	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000652
BRD-K47832606-001-30-1	ACH-000452	TE8_OESOPHAGUS	HTS002	1	0.27276	1.583684	0.47985	0.695791	0.172776	0.284278	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000452
BRD-K47832606-001-30-1	ACH-000458	CJM_SKIN	HTS002	1	0.198383	3.569139	0.692556	0.647301	0.139867	0.161145	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000458
BRD-K47832606-001-30-1	ACH-000221	SNU398_LIVER	HTS002	1	0.199893	2.031854	0.524884	0.6045	0.08256	0.106141	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000221
BRD-K47832606-001-30-1	ACH-000970	SNUC5_LARGE_INTESTINE	HTS002	1	2.317933	-0.147893	-0.000009	1.426791	0.000439	null	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000970
BRD-K47832606-001-30-1	ACH-000893	NCIH1651_LUNG	HTS002	1	0.395692	3.594602	0.652423	0.637095	0.029452	0.045547	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000893
BRD-K47832606-001-30-1	ACH-000562	HCC78_LUNG	HTS002	1	0.174816	3.372536	0.763555	0.512746	0.032469	0.036887	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000562
BRD-K47832606-001-30-1	ACH-000769	LK2_LUNG	HTS002	1	0.288916	2.933945	0.56491	0.636669	0.070246	0.094247	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000769
BRD-K47832606-001-30-1	ACH-000384	SW780_URINARY_TRACT	HTS002	1	0.572179	4.187353	0.325864	0.821473	0.17432	null	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000384
BRD-K47832606-001-30-1	ACH-000505	RKN_SOFT_TISSUE	HTS002	1	0.251319	4.896341	0.671053	0.656345	0.116284	0.134113	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000505
BRD-K47832606-001-30-1	ACH-000765	WM983B_SKIN	HTS002	1	0.137913	2.154205	0.670406	0.680375	0.273879	0.318142	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000765
BRD-K47832606-001-30-1	ACH-000858	KNS62_LUNG	HTS002	1	0.442374	2.195706	0.216692	0.64032	0.019121	0.051152	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000858
BRD-K47832606-001-30-1	ACH-000595	LN229_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.157089	1.237356	0.421205	0.734458	0.478981	0.649663	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000595
BRD-K47832606-001-30-1	ACH-000052	A673_BONE	HTS002	1	0.337332	1.986601	0.495528	0.615691	0.035959	0.063283	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000052
BRD-K47832606-001-30-1	ACH-000979	DU145_PROSTATE	HTS002	1	0.203092	3.749667	0.890413	0.612026	0.088758	0.101994	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000979
BRD-K47832606-001-30-1	ACH-000571	T98G_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.081647	1.476765	0.952634	0.406567	0.01883	0.021246	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000571
BRD-K47832606-001-30-1	ACH-000812	COLO783_SKIN	HTS002	1	0.223115	5.205187	0.814967	0.633784	0.103124	0.115523	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000812
BRD-K47832606-001-30-1	ACH-000891	HCC1438_LUNG	HTS002	1	0.176344	12.458439	0.824526	0.588064	0.078025	0.080797	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000891
BRD-K47832606-001-30-1	ACH-000667	HCC44_LUNG	HTS002	1	0.162717	1.904424	0.810016	0.535015	0.045652	0.056136	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000667
BRD-K47832606-001-30-1	ACH-000734	JHH5_LIVER	HTS002	1	0.13956	2.102674	0.540175	0.361914	0.007475	0.008734	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000734
BRD-K47832606-001-30-1	ACH-000416	NCIH838_LUNG	HTS002	1	0.133998	2.289273	0.960654	0.528932	0.050995	0.05844	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000416
BRD-K47832606-001-30-1	ACH-000802	BFTC905_URINARY_TRACT	HTS002	1	0.251739	2.541329	0.498422	0.631981	0.084568	0.111392	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000802
BRD-K47832606-001-30-1	ACH-000946	HEC265_ENDOMETRIUM	HTS002	1	0.187408	6.38216	0.420263	0.617082	0.103284	0.111172	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000946
BRD-K47832606-001-30-1	ACH-000472	HSC2_UPPER_AERODIGESTIVE_TRACT	HTS002	1	0.145892	1.928602	0.812578	0.573906	0.078981	0.094453	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000472
BRD-K47832606-001-30-1	ACH-000962	OC314_OVARY	HTS002	1	0.044863	9.357182	0.908821	0.46248	0.042487	0.042916	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000962
BRD-K47832606-001-30-1	ACH-000383	OE33_OESOPHAGUS	HTS002	1	0.239397	6.647969	0.925557	0.451535	0.009141	0.010083	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000383
BRD-K47832606-001-30-1	ACH-000824	KYSE510_OESOPHAGUS	HTS002	1	0.049243	1.548062	0.88339	0.508714	0.066404	0.071004	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000824
BRD-K47832606-001-30-1	ACH-001307	8505C_THYROID	HTS002	1	0.312311	1.91373	0.392441	0.839594	1.047055	1.747136	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-001307
BRD-K47832606-001-30-1	ACH-000756	GI1_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.104418	1.424862	0.729992	0.591842	0.120139	0.141606	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000756
BRD-K47832606-001-30-1	ACH-000681	A549_LUNG	HTS002	1	0.266427	4.954124	0.727182	0.651074	0.098945	0.115376	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000681
BRD-K47832606-001-30-1	ACH-000444	LU99_LUNG	HTS002	1	0.155466	3.694117	0.758193	0.614903	0.119749	0.13245	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000444
BRD-K47832606-001-30-1	ACH-000142	CAL29_URINARY_TRACT	HTS002	1	0.11322	3.792568	0.727764	0.485813	0.036001	0.038523	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000142
BRD-K47832606-001-30-1	ACH-000905	5637_URINARY_TRACT	HTS002	1	0.101737	3.329597	0.761006	0.335009	0.007586	0.008122	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000905
BRD-K47832606-001-30-1	ACH-000680	SW948_LARGE_INTESTINE	HTS002	1	0.120941	1.737752	0.702665	0.462996	0.026615	0.031213	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000680

BRD-K47832606-001-30-1

ACH-000663

OVTOKO_OVARY

HTS002

1

0.219316

8.515367

0.612144

0.636947

0.109674

0.117368

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000663

BRD-K47832606-001-30-1

ACH-000647

TE1_OESOPHAGUS

HTS002

1

0.230715

1.747896

0.672697

0.607636

0.070871

0.100979

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000647

BRD-K47832606-001-30-1

ACH-000243

DANG_PANCREAS

HTS002

1

0.284159

4.281361

0.640799

0.612532

0.052339

0.063686

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000243

BRD-K47832606-001-30-1

ACH-000255

LMSU_STOMACH

HTS002

1

0.033488

11.078989

0.84709

0.54994

0.109027

0.109712

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000255

BRD-K47832606-001-30-1

ACH-000335

MSTO211H_PLEURA

HTS002

1

0.067022

10.860529

0.800652

0.451965

0.033452

0.033899

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000335

BRD-K47832606-001-30-1

ACH-000147

T47D_BREAST

HTS002

1

0.266885

2.834215

0.636041

0.576143

0.036592

0.047898

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000147

BRD-K47832606-001-30-1

ACH-000090

PC3_PROSTATE

HTS002

1

0.097811

0.844409

0.814521

0.483654

0.037759

0.048863

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000090

BRD-K47832606-001-30-1

ACH-000171

VMRCRCZ_KIDNEY

HTS002

1

0.67773

3.780734

0.021568

0.862028

0.156925

null

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000171

BRD-K47832606-001-30-1

ACH-000614

RVH421_SKIN

HTS002

1

0.300601

1.302141

0.658963

0.631791

0.060373

0.122306

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000614

BRD-K47832606-001-30-1

ACH-000132

JHOS2_OVARY

HTS002

1

0.254363

12.338974

0.686919

0.63132

0.082447

0.087336

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000132

BRD-K47832606-001-30-1

ACH-000274

HS852T_SKIN

HTS002

1

0.271823

1.238714

0.129492

0.729425

0.274079

0.516319

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000274

BRD-K47832606-001-30-1

null

HTS002

1

0.179773

2.517844

0.760872

0.623013

0.11561

0.137991

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

false

ACH-000807_FAILED_STR

BRD-K47832606-001-30-1

ACH-000810

SKMEL30_SKIN

HTS002

1

0.395335

4.163172

0.414604

0.729584

0.130389

0.189836

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000810

BRD-K47832606-001-30-1

ACH-000343

NCIH522_LUNG

HTS002

1

0.354323

3.674071

0.356496

0.703065

0.115308

0.161299

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000343

BRD-K47832606-001-30-1

ACH-000022

PATU8988S_PANCREAS

HTS002

1

0.668989

2.629579

-0.058998

0.796441

0.025602

null

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000022

BRD-K47832606-001-30-1

ACH-000192

MFE280_ENDOMETRIUM

HTS002

1

0.192636

2.189467

0.595645

0.589738

0.072184

0.090148

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000192

BRD-K47832606-001-30-1

null

HTS002

1

0.228342

3.112621

0.721031

0.569541

0.04457

0.05422

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

false

ACH-000409_FAILED_STR

BRD-K47832606-001-30-1

ACH-000959

SNUC4_LARGE_INTESTINE

HTS002

1

0.128105

3.962022

0.802776

0.358158

0.007899

0.008512

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000959

BRD-K47832606-001-30-1

null

HTS002

1

0.322935

2.704883

0.915784

0.602132

0.033377

0.048991

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

false

ACH-000028_FAILED_STR

BRD-K47832606-001-30-1

ACH-000637

KYSE520_OESOPHAGUS

HTS002

1

0.228877

1.215429

0.702417

0.65952

0.138242

0.228734

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000637

BRD-K47832606-001-30-1

ACH-000968

COLO792_SKIN

HTS002

1

0.342563

4.328023

0.380967

0.715473

0.149994

0.195898

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000968

BRD-K47832606-001-30-1

ACH-000155

SW1990_PANCREAS

HTS002

1

0.214757

1.930037

0.842483

0.591478

0.064185

0.085848

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000155

BRD-K47832606-001-30-1

ACH-000133

HS729_SOFT_TISSUE

HTS002

1

0.123818

2.503209

0.673605

0.519727

0.048965

0.05486

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000133

BRD-K47832606-001-30-1

ACH-000605

TE6_OESOPHAGUS

HTS002

1

0.247221

2.059205

0.754324

0.558556

0.03377

0.047031

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000605

BRD-K47832606-001-30-1

ACH-000775

NCIH727_LUNG

HTS002

1

1.340129

-6.886617

0.305596

1.168191

0.074058

null

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000775

BRD-K47832606-001-30-1

ACH-000042

PANC0203_PANCREAS

HTS002

1

0.292173

2.262436

0.565339

0.588604

0.035523

0.052364

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000042

BRD-K47832606-001-30-1

ACH-000860

NCIH358_LUNG

HTS002

1

0.375951

5.522596

0.760798

0.706897

0.104851

0.134956

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000860

BRD-K47832606-001-30-1

ACH-000994

HEC59_ENDOMETRIUM

HTS002

1

0.107773

0.807705

0.68558

0.651699

0.237732

0.321086

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000994

BRD-K47832606-001-30-1

ACH-000277

HCC1419_BREAST

HTS002

1

0.402657

5.472122

0.539262

0.726524

0.117639

0.158643

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000277

BRD-K47832606-001-30-1

ACH-000496

NCIH1792_LUNG

HTS002

1

0.170276

2.522395

0.415104

0.586879

0.079732

0.094041

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000496

BRD-K47832606-001-30-1

ACH-000866

NCIH1048_LUNG

HTS002

1

0.057024

1.36146

0.811312

0.385988

0.017893

0.019557

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000866

BRD-K47832606-001-30-1

ACH-000869

NCIH1568_LUNG

HTS002

1

0.168328

3.38637

0.66567

0.516826

0.035609

0.040197

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000869

BRD-K47832606-001-30-1

ACH-000117

EFM192A_BREAST

HTS002

1

0.467316

1.752502

0.269928

0.769721

0.150749

0.714856

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000117

BRD-K47832606-001-30-1

ACH-000678

MKN7_STOMACH

HTS002

1

0.344349

2.341931

0.572858

0.634767

0.044909

0.073917

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000678

BRD-K47832606-001-30-1

ACH-000493

SNU423_LIVER

HTS002

1

0.102317

1.12875

0.714851

0.480335

0.036068

0.044179

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000493

BRD-K47832606-001-30-1

ACH-000468

PK45H_PANCREAS

HTS002

1

0.509025

1.601809

0.417446

0.793847

0.170132

null

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000468

BRD-K47832606-001-30-1

ACH-000097

ZR751_BREAST

HTS002

1

0.156175

1.389226

0.685561

0.695568

0.303319

0.397161

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000097

BRD-K47832606-001-30-1

ACH-000313

KMRC3_KIDNEY

HTS002

1

0.2122

1.311834

0.760344

0.593288

0.066682

0.101594

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000313

BRD-K47832606-001-30-1

ACH-000169

RD_SOFT_TISSUE

HTS002

1

0.043979

0.976793

0.569177

0.538843

0.092982

0.102172

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000169

BRD-K47832606-001-30-1

null

HTS002

1

0.153958

4.204517

0.76929

0.496968

0.031205

0.03406

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

false

ACH-000010_FAILED_STR

BRD-K47832606-001-30-1

ACH-000895

CL34_LARGE_INTESTINE

HTS002

1

0.180361

6.295257

0.355604

0.554725

0.051343

0.055125

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000895

BRD-K47832606-001-30-1

ACH-000841

NCIH2087_LUNG

HTS002

1

0.176174

2.567031

0.692966

0.588456

0.078464

0.092932

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000841

BRD-K47832606-001-30-1

ACH-000414

NCIH1944_LUNG

HTS002

1

0.049855

9.144912

0.788346

0.464332

0.042074

0.04256

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000414

BRD-K47832606-001-30-1

ACH-000026

253JBV_URINARY_TRACT

HTS002

1

0.179625

1.388001

0.649139

0.707212

0.315066

0.434186

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000026

BRD-K47832606-001-30-1

ACH-000649

786O_KIDNEY

HTS002

1

0.211157

11.675057

0.748381

0.605516

0.078065

0.081821

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000649

BRD-K47832606-001-30-1

ACH-000966

IGROV1_OVARY

HTS002

1

0.17933

2.42986

0.824199

0.604089

0.092653

0.111238

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000966

BRD-K47832606-001-30-1

ACH-000950

LOVO_LARGE_INTESTINE

HTS002

1

0.153047

3.645718

0.7834

0.497731

0.031675

0.035014

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000950

BRD-K47832606-001-30-1

ACH-000750

LOXIMVI_SKIN

HTS002

1

0.333666

8.296873

0.51667

0.678583

0.092706

0.105856

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000750

BRD-K47832606-001-30-1

ACH-000958

SW48_LARGE_INTESTINE

HTS002

1

0.266774

0.503806

-0.093518

0.537133

0.01677

0.076195

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000958

BRD-K47832606-001-30-1

ACH-000270

HPAC_PANCREAS

HTS002

1

0.329027

2.058033

0.463504

0.613063

0.037117

0.062521

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000270

BRD-K47832606-001-30-1

ACH-000535

BXPC3_PANCREAS

HTS002

1

1.263033

-0.680512

0.021593

1.069793

0.006128

null

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000535

BRD-K47832606-001-30-1

ACH-000480

HUH7_LIVER

HTS002

1

1.381123

-0.059533

0.000364

1.230998

114.292282

null

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000480

BRD-K47832606-001-30-1

ACH-000281

KP2_PANCREAS

HTS002

1

1.386105

-5.223036

0.289613

1.176107

0.05103

null

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000281

BRD-K47832606-001-30-1

ACH-000897

FTC238_THYROID

HTS002

1

0.152916

6.311568

0.442876

0.608675

0.112999

0.119727

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000897

BRD-K47832606-001-30-1

ACH-000389

H4_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.374167

1.898738

0.39534

0.639504

0.03735

0.077243

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000389

BRD-K47832606-001-30-1

ACH-000862

KMBC2_URINARY_TRACT

HTS002

1

0.159287

5.304975

0.913682

0.508549

0.034387

0.036965

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000862

BRD-K47832606-001-30-1

ACH-000776

ONS76_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.250975

1.436514

0.79145

0.575295

0.040716

0.066146

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000776

BRD-K47832606-001-30-1

ACH-000023

PATU8988T_PANCREAS

HTS002

1

0.157098

2.568904

0.958449

0.553352

0.058452

0.067696

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000023

BRD-K47832606-001-30-1

ACH-000011

253J_URINARY_TRACT

HTS002

1

0.192388

2.218039

0.829035

0.591061

0.073451

0.091435

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000011

BRD-K47832606-001-30-1

ACH-000973

639V_URINARY_TRACT

HTS002

1

0.053086

4.674771

0.926368

0.299903

0.007657

0.007843

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000973

BRD-K47832606-001-30-1

ACH-001024

CHL1_SKIN

HTS002

1

0.195194

1.992654

0.667592

0.590995

0.072146

0.092487

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-001024

BRD-K47832606-001-30-1

ACH-000971

HCT116_LARGE_INTESTINE

HTS002

1

0.20295

1.861161

0.850531

0.610653

0.087363

0.115566

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000971

BRD-K47832606-001-30-1

ACH-000486

KU1919_URINARY_TRACT

HTS002

1

0.108403

2.444954

0.866664

0.449017

0.024864

0.027478

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000486

BRD-K47832606-001-30-1

ACH-000997

HCT15_LARGE_INTESTINE

HTS002

1

0.083699

3.920667

0.704994

0.492596

0.046371

0.048589

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000997

BRD-K47832606-001-30-1

ACH-000552

HT29_LARGE_INTESTINE

HTS002

1

0.157672

2.410343

0.720447

0.465697

0.021217

0.024828

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000552

BRD-K47832606-001-30-1

ACH-000796

MCAS_OVARY

HTS002

1

0.225379

2.652252

0.825676

0.615566

0.080991

0.101521

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000796

BRD-K47832606-001-30-1

ACH-000652

SUIT2_PANCREAS

HTS002

1

0.314497

1.637776

0.696319

0.646922

0.067492

0.123646

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000652

BRD-K47832606-001-30-1

ACH-000452

TE8_OESOPHAGUS

HTS002

1

0.27276

1.583684

0.47985

0.695791

0.172776

0.284278

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000452

BRD-K47832606-001-30-1

ACH-000458

CJM_SKIN

HTS002

1

0.198383

3.569139

0.692556

0.647301

0.139867

0.161145

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000458

BRD-K47832606-001-30-1

ACH-000221

SNU398_LIVER

HTS002

1

0.199893

2.031854

0.524884

0.6045

0.08256

0.106141

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000221

BRD-K47832606-001-30-1

ACH-000970

SNUC5_LARGE_INTESTINE

HTS002

1

2.317933

-0.147893

-0.000009

1.426791

0.000439

null

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000970

BRD-K47832606-001-30-1

ACH-000893

NCIH1651_LUNG

HTS002

1

0.395692

3.594602

0.652423

0.637095

0.029452

0.045547

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000893

BRD-K47832606-001-30-1

ACH-000562

HCC78_LUNG

HTS002

1

0.174816

3.372536

0.763555

0.512746

0.032469

0.036887

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000562

BRD-K47832606-001-30-1

ACH-000769

LK2_LUNG

HTS002

1

0.288916

2.933945

0.56491

0.636669

0.070246

0.094247

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000769

BRD-K47832606-001-30-1

ACH-000384

SW780_URINARY_TRACT

HTS002

1

0.572179

4.187353

0.325864

0.821473

0.17432

null

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000384

BRD-K47832606-001-30-1

ACH-000505

RKN_SOFT_TISSUE

HTS002

1

0.251319

4.896341

0.671053

0.656345

0.116284

0.134113

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000505

BRD-K47832606-001-30-1

ACH-000765

WM983B_SKIN

HTS002

1

0.137913

2.154205

0.670406

0.680375

0.273879

0.318142

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000765

BRD-K47832606-001-30-1

ACH-000858

KNS62_LUNG

HTS002

1

0.442374

2.195706

0.216692

0.64032

0.019121

0.051152

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000858

BRD-K47832606-001-30-1

ACH-000595

LN229_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.157089

1.237356

0.421205

0.734458

0.478981

0.649663

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000595

BRD-K47832606-001-30-1

ACH-000052

A673_BONE

HTS002

1

0.337332

1.986601

0.495528

0.615691

0.035959

0.063283

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000052

BRD-K47832606-001-30-1

ACH-000979

DU145_PROSTATE

HTS002

1

0.203092

3.749667

0.890413

0.612026

0.088758

0.101994

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000979

BRD-K47832606-001-30-1

ACH-000571

T98G_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.081647

1.476765

0.952634

0.406567

0.01883

0.021246

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000571

BRD-K47832606-001-30-1

ACH-000812

COLO783_SKIN

HTS002

1

0.223115

5.205187

0.814967

0.633784

0.103124

0.115523

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000812

BRD-K47832606-001-30-1

ACH-000891

HCC1438_LUNG

HTS002

1

0.176344

12.458439

0.824526

0.588064

0.078025

0.080797

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000891

BRD-K47832606-001-30-1

ACH-000667

HCC44_LUNG

HTS002

1

0.162717

1.904424

0.810016

0.535015

0.045652

0.056136

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000667

BRD-K47832606-001-30-1

ACH-000734

JHH5_LIVER

HTS002

1

0.13956

2.102674

0.540175

0.361914

0.007475

0.008734

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000734

BRD-K47832606-001-30-1

ACH-000416

NCIH838_LUNG

HTS002

1

0.133998

2.289273

0.960654

0.528932

0.050995

0.05844

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000416

BRD-K47832606-001-30-1

ACH-000802

BFTC905_URINARY_TRACT

HTS002

1

0.251739

2.541329

0.498422

0.631981

0.084568

0.111392

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000802

BRD-K47832606-001-30-1

ACH-000946

HEC265_ENDOMETRIUM

HTS002

1

0.187408

6.38216

0.420263

0.617082

0.103284

0.111172

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000946

BRD-K47832606-001-30-1

ACH-000472

HSC2_UPPER_AERODIGESTIVE_TRACT

HTS002

1

0.145892

1.928602

0.812578

0.573906

0.078981

0.094453

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000472

BRD-K47832606-001-30-1

ACH-000962

OC314_OVARY

HTS002

1

0.044863

9.357182

0.908821

0.46248

0.042487

0.042916

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000962

BRD-K47832606-001-30-1

ACH-000383

OE33_OESOPHAGUS

HTS002

1

0.239397

6.647969

0.925557

0.451535

0.009141

0.010083

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000383

BRD-K47832606-001-30-1

ACH-000824

KYSE510_OESOPHAGUS

HTS002

1

0.049243

1.548062

0.88339

0.508714

0.066404

0.071004

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000824

BRD-K47832606-001-30-1

ACH-001307

8505C_THYROID

HTS002

1

0.312311

1.91373

0.392441

0.839594

1.047055

1.747136

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-001307

BRD-K47832606-001-30-1

ACH-000756

GI1_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.104418

1.424862

0.729992

0.591842

0.120139

0.141606

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000756

BRD-K47832606-001-30-1

ACH-000681

A549_LUNG

HTS002

1

0.266427

4.954124

0.727182

0.651074

0.098945

0.115376

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000681

BRD-K47832606-001-30-1

ACH-000444

LU99_LUNG

HTS002

1

0.155466

3.694117

0.758193

0.614903

0.119749

0.13245

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000444

BRD-K47832606-001-30-1

ACH-000142

CAL29_URINARY_TRACT

HTS002

1

0.11322

3.792568

0.727764

0.485813

0.036001

0.038523

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000142

BRD-K47832606-001-30-1

ACH-000905

5637_URINARY_TRACT

HTS002

1

0.101737

3.329597

0.761006

0.335009

0.007586

0.008122

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000905

BRD-K47832606-001-30-1

ACH-000680

SW948_LARGE_INTESTINE

HTS002

1

0.120941

1.737752

0.702665

0.462996

0.026615

0.031213

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000680