donb-hf/secondary-screen-dose-response-curve-parameters

broad_id string	depmap_id string	ccle_name string	screen_id string	upper_limit int64	lower_limit float64	slope float64	r2 float64	auc float64	ec50 float64	ic50 float64	name string	moa string	target string	disease.area string	indication string	smiles string	phase string	passed_str_profiling bool	row_name string
BRD-K47832606-001-30-1	ACH-000921	NCIH1339_LUNG	HTS002	1	0.169494	1.82881	0.790841	0.684057	0.249465	0.312838	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000921
BRD-K47832606-001-30-1	ACH-000954	HEC1A_ENDOMETRIUM	HTS002	1	0.200005	2.659634	0.77066	0.557639	0.046732	0.056628	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000954
BRD-K47832606-001-30-1	ACH-000280	SNU840_OVARY	HTS002	1	0.189876	1.468523	0.947519	0.511865	0.028817	0.039894	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000280
BRD-K47832606-001-30-1	ACH-000012	HCC827_LUNG	HTS002	1	0.177713	2.886328	0.766551	0.526909	0.037609	0.043789	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000012
BRD-K47832606-001-30-1	ACH-000098	GAMG_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.349984	3.49056	0.351852	0.716399	0.144961	0.204661	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000098
BRD-K47832606-001-30-1	ACH-000589	NCIH1437_LUNG	HTS002	1	0.21324	1.239762	0.851529	0.520466	0.026811	0.041982	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000589
BRD-K47832606-001-30-1	ACH-000738	GB1_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.260991	2.110599	0.554954	0.696951	0.186989	0.265274	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000738
BRD-K47832606-001-30-1	ACH-000837	NCIH322_LUNG	HTS002	1	0.186471	2.270251	0.779305	0.573366	0.061638	0.075706	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000837
BRD-K47832606-001-30-1	ACH-000967	SNUC2A_LARGE_INTESTINE	HTS002	1	0.36318	4.146739	0.643656	0.651701	0.049543	0.067718	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000967
BRD-K47832606-001-30-1	ACH-000662	CORL23_LUNG	HTS002	1	0.325649	2.242026	0.536406	0.640754	0.056865	0.090976	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000662
BRD-K47832606-001-30-1	ACH-000427	NCIN87_STOMACH	HTS002	1	0.985824	0.724332	-0.040625	0.992083	0.042747	null	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000427
BRD-K47832606-001-30-1	ACH-000774	RERFLCAD2_LUNG	HTS002	1	0.404402	2.458731	0.320509	0.861681	1.051848	2.061513	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000774
BRD-K47832606-001-30-1	ACH-000624	HCC1806_BREAST	HTS002	1	0.131288	1.982768	0.781656	0.40447	0.012893	0.015034	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000624
BRD-K47832606-001-30-1	ACH-000888	NCIH1793_LUNG	HTS002	1	0.62223	1.790772	0.452514	0.843431	0.179255	null	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000888
BRD-K47832606-001-30-1	ACH-000449	MESSA_SOFT_TISSUE	HTS002	1	0.121416	3.094364	0.70735	0.537901	0.060727	0.066439	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000449
BRD-K47832606-001-30-1	ACH-000587	NCIH1975_LUNG	HTS002	1	0.189755	2.948271	0.800872	0.538989	0.040002	0.047031	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000587
BRD-K47832606-001-30-1	ACH-000404	K029AX_SKIN	HTS002	1	0.242322	4.206711	0.421293	0.672698	0.151165	0.176965	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000404
BRD-K47832606-001-30-1	ACH-000813	T3M10_LUNG	HTS002	1	0.110118	1.884296	0.683038	0.505854	0.045677	0.052123	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000813
BRD-K47832606-001-30-1	ACH-000311	NCIH2122_LUNG	HTS002	1	0.19299	3.066034	0.626347	0.556452	0.048269	0.056592	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000311
BRD-K47832606-001-30-1	ACH-000849	MDAMB468_BREAST	HTS002	1	0.302233	4.096219	0.741446	0.652405	0.079537	0.099749	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000849
BRD-K47832606-001-30-1	ACH-000868	HCC1195_LUNG	HTS002	1	0.362891	4.972981	0.565683	0.626406	0.033783	0.043822	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000868
BRD-K47832606-001-30-1	ACH-000978	EN_ENDOMETRIUM	HTS002	1	1.567675	-0.476239	0.123242	1.21921	0.019975	null	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000978
BRD-K47832606-001-30-1	ACH-000408	TE5_OESOPHAGUS	HTS002	1	0.441971	4.047398	0.663495	0.747628	0.124164	0.211393	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000408
BRD-K47832606-001-30-1	ACH-000344	SNU668_STOMACH	HTS002	1	0.411234	1.656151	0.689852	0.672819	0.045482	0.129163	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000344
BRD-K47832606-001-30-1	ACH-000161	CORL105_LUNG	HTS002	1	0.290168	0.953168	0.374065	0.746427	0.323843	0.805307	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000161
BRD-K47832606-001-30-1	ACH-000835	GCT_SOFT_TISSUE	HTS002	1	0.29838	2.329911	0.61829	0.668198	0.101617	0.150058	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000835
BRD-K47832606-001-30-1	ACH-000819	LN18_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.128059	4.740864	0.94249	0.536027	0.057206	0.06089	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000819
BRD-K47832606-001-30-1	ACH-000062	RERFLCMS_LUNG	HTS002	1	0.107584	3.25189	0.662667	0.579299	0.103096	0.111071	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000062
BRD-K47832606-001-30-1	ACH-000473	RT112_URINARY_TRACT	HTS002	1	0.06352	12.698418	0.824702	0.462981	0.038305	0.038717	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000473
BRD-K47832606-001-30-1	ACH-000176	LOUNH91_LUNG	HTS002	1	0.11798	2.871783	0.880034	0.488746	0.03607	0.039614	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000176
BRD-K47832606-001-30-1	ACH-000445	KNS60_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.196759	3.457669	0.814226	0.572092	0.056867	0.065716	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000445
BRD-K47832606-001-30-1	ACH-000331	ISTMES2_PLEURA	HTS002	1	0.358737	12.070301	0.372135	0.680629	0.079629	0.088419	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000331
BRD-K47832606-001-30-1	ACH-000163	SW579_THYROID	HTS002	1	0.164713	1.170134	0.428557	0.540462	0.047849	0.067328	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000163
BRD-K47832606-001-30-1	ACH-000768	MDAMB231_BREAST	HTS002	1	0.239316	1.960808	0.578707	0.621872	0.080363	0.112024	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000768
BRD-K47832606-001-30-1	null	null	HTS002	1	0.05041	0.561882	0.437837	0.303972	0.005249	0.006341	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	false	ACH-001078_FAILED_STR
BRD-K47832606-001-30-1	ACH-000778	HSC3_UPPER_AERODIGESTIVE_TRACT	HTS002	1	0.074189	2.661799	0.86234	0.454647	0.032921	0.034968	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000778
BRD-K47832606-001-30-1	ACH-000881	MELJUSO_SKIN	HTS002	1	0.196763	3.503941	0.732898	0.614442	0.094853	0.109404	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000881
BRD-K47832606-001-30-1	ACH-000521	NCIH2030_LUNG	HTS002	1	0.211607	3.173448	0.713728	0.590132	0.064419	0.076616	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000521
BRD-K47832606-001-30-1	ACH-000696	OVCAR8_OVARY	HTS002	1	0.161941	1.125809	0.688106	0.608008	0.107136	0.151677	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000696
BRD-K47832606-001-30-1	ACH-000972	HEC151_ENDOMETRIUM	HTS002	1	0.276732	2.204517	0.762872	0.617231	0.058834	0.084812	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000972
BRD-K47832606-001-30-1	ACH-000242	RT4_URINARY_TRACT	HTS002	1	0.289187	2.207249	0.458751	0.587009	0.035591	0.052634	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000242
BRD-K47832606-001-30-1	ACH-000087	SKES1_BONE	HTS002	1	0.030887	1.886249	0.469147	0.478134	0.053765	0.055613	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000087
BRD-K47832606-001-30-1	ACH-000926	HT55_LARGE_INTESTINE	HTS002	1	0.448312	3.259429	0.579317	0.70061	0.051632	0.103585	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000926
BRD-K47832606-001-30-1	ACH-000356	MKN45_STOMACH	HTS002	1	0.084907	2.797742	0.756918	0.481494	0.04093	0.043745	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000356
BRD-K47832606-001-30-1	ACH-000625	HEP3B217_LIVER	HTS002	1	0.246606	1.206595	0.608001	0.633831	0.089541	0.157273	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000625
BRD-K47832606-001-30-1	ACH-000613	HOS_BONE	HTS002	1	0.138001	4.089765	0.553498	0.611932	0.126673	0.137082	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000613
BRD-K47832606-001-30-1	ACH-000976	HUCCT1_BILIARY_TRACT	HTS002	1	0.271249	3.448229	0.757872	0.588434	0.041676	0.052284	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000976
BRD-K47832606-001-30-1	ACH-001075	NCIH292_LUNG	HTS002	1	0.223213	1.474779	0.671783	0.50024	0.019356	0.028904	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-001075
BRD-K47832606-001-30-1	ACH-000261	RERFLCAI_LUNG	HTS002	1	0.143605	1.705271	0.770959	0.629339	0.150004	0.182949	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000261
BRD-K47832606-001-30-1	ACH-000957	LS180_LARGE_INTESTINE	HTS002	1	0.254328	1.808122	0.715066	0.507687	0.016478	0.024411	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000957
BRD-K47832606-001-30-1	ACH-000099	SIMA_AUTONOMIC_GANGLIA	HTS002	1	0.193772	3.632987	0.614956	0.534736	0.036975	0.042317	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000099
BRD-K47832606-001-30-1	ACH-000783	CAMA1_BREAST	HTS002	1	1.621309	-1.298574	-0.012204	1.200247	0.013745	null	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000783
BRD-K47832606-001-30-1	ACH-000573	MDAMB436_BREAST	HTS002	1	0.371764	14.776771	0.784738	0.689129	0.082143	0.090067	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000573
BRD-K47832606-001-30-1	ACH-000852	NCIH1435_LUNG	HTS002	1	0.56816	3.68613	0.354571	0.883621	0.731531	null	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000852
BRD-K47832606-001-30-1	ACH-000461	SNU1196_BILIARY_TRACT	HTS002	1	0.331582	5.032273	0.485674	0.709706	0.1478	0.183479	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000461
BRD-K47832606-001-30-1	ACH-000420	SNU449_LIVER	HTS002	1	0.375142	5.679479	0.516762	0.73405	0.160794	0.205288	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000420
BRD-K47832606-001-30-1	ACH-000694	TE9_OESOPHAGUS	HTS002	1	0.225925	4.221378	0.517611	0.635029	0.103021	0.118789	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000694
BRD-K47832606-001-30-1	ACH-000528	ABC1_LUNG	HTS002	1	0.393977	4.296893	0.690018	0.708719	0.094268	0.135246	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000528
BRD-K47832606-001-30-1	ACH-000845	NCIH1373_LUNG	HTS002	1	0.304119	2.175101	0.769603	0.644042	0.06986	0.107483	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000845
BRD-K47832606-001-30-1	ACH-000563	EBC1_LUNG	HTS002	1	0.083177	12.905709	0.846091	0.471026	0.037019	0.037545	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000563
BRD-K47832606-001-30-1	ACH-000665	SKMES1_LUNG	HTS002	1	0.216734	2.1144	0.848133	0.575609	0.052061	0.068112	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000665
BRD-K47832606-001-30-1	ACH-000467	HCC56_LARGE_INTESTINE	HTS002	1	0.078884	4.517785	0.761892	0.336164	0.009177	0.009533	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000467
BRD-K47832606-001-30-1	ACH-000201	A204_SOFT_TISSUE	HTS002	1	0.161277	2.014529	0.722435	0.541032	0.049402	0.059937	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000201
BRD-K47832606-001-30-1	ACH-000296	OUMS23_LARGE_INTESTINE	HTS002	1	0.440999	2.476938	0.500134	0.774147	0.19827	0.469848	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000296
BRD-K47832606-001-30-1	ACH-000189	RCC10RGB_KIDNEY	HTS002	1	0.207143	1.580282	0.761001	0.595156	0.070472	0.09886	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000189
BRD-K47832606-001-30-1	ACH-000791	RERFLCAD1_LUNG	HTS002	1	0.292718	6.46605	0.653089	0.671678	0.110574	0.126706	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000791
BRD-K47832606-001-30-1	ACH-000367	NCIH226_LUNG	HTS002	1	0.258068	3.407205	0.809815	0.641351	0.091781	0.113576	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000367
BRD-K47832606-001-30-1	ACH-001190	SKMEL2_SKIN	HTS002	1	0.374845	9.348433	0.460362	0.688212	0.079088	0.091718	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-001190
BRD-K47832606-001-30-1	ACH-000244	DKMG_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.280163	3.83528	0.784052	0.605943	0.049307	0.061089	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000244
BRD-K47832606-001-30-1	ACH-000713	CAOV3_OVARY	HTS002	1	0.0616	9.608751	0.778583	0.55478	0.100111	0.10149	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000713
BRD-K47832606-001-30-1	ACH-000672	IALM_LUNG	HTS002	1	0.322105	4.114544	0.439721	0.690545	0.119163	0.153186	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000672
BRD-K47832606-001-30-1	ACH-000875	NCIH2347_LUNG	HTS002	1	0.169215	0.698842	0.556681	0.620551	0.122471	0.221198	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000875
BRD-K47832606-001-30-1	ACH-000423	SKMEL3_SKIN	HTS002	1	0.585987	4.551335	0.490775	0.809744	0.115691	null	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000423
BRD-K47832606-001-30-1	ACH-000553	SQ1_LUNG	HTS002	1	0.40791	4.88194	0.516194	0.718773	0.0996	0.140852	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000553
BRD-K47832606-001-30-1	ACH-000834	UMUC1_URINARY_TRACT	HTS002	1	0.119878	1.820252	0.718027	0.418062	0.016323	0.018976	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000834
BRD-K47832606-001-30-1	ACH-000252	LS1034_LARGE_INTESTINE	HTS002	1	0.513032	3.974213	0.306433	0.74386	0.060709	null	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000252
BRD-K47832606-001-30-1	ACH-000123	COV434_OVARY	HTS002	1	0.026299	0.579829	0.523142	0.439563	0.034051	0.037376	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000123
BRD-K47832606-001-30-1	ACH-000329	CCFSTTG1_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.232952	1.495068	0.511267	0.62411	0.086058	0.130911	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000329
BRD-K47832606-001-30-1	ACH-000717	COLO680N_OESOPHAGUS	HTS002	1	0.215787	1.49487	0.702824	0.624773	0.0963	0.140521	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000717
BRD-K47832606-001-30-1	ACH-000669	SW900_LUNG	HTS002	1	0.222897	1.103438	0.475873	0.508519	0.021245	0.036271	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000669
BRD-K47832606-001-30-1	ACH-000764	SH10TC_STOMACH	HTS002	1	0.232884	1.690393	0.8222	0.595064	0.059603	0.086365	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000764
BRD-K47832606-001-30-1	ACH-000288	BT549_BREAST	HTS002	1	0.050668	1.127577	0.762202	0.438258	0.031796	0.034956	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000288
BRD-K47832606-001-30-1	ACH-000415	BICR6_UPPER_AERODIGESTIVE_TRACT	HTS002	1	0.111429	1.250427	0.417703	0.50168	0.043172	0.052817	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000415
BRD-K47832606-001-30-1	ACH-000228	BICR31_UPPER_AERODIGESTIVE_TRACT	HTS002	1	0.306331	5.717314	0.71968	0.664541	0.0916	0.108129	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000228
BRD-K47832606-001-30-1	ACH-000977	LNCAPCLONEFGC_PROSTATE	HTS002	1	0.128318	3.397889	0.803044	0.61664	0.140127	0.152907	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000977
BRD-K47832606-001-30-1	ACH-000397	TEN_ENDOMETRIUM	HTS002	1	0.405271	1.231733	0.279145	0.734059	0.130819	0.504931	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000397
BRD-K47832606-001-30-1	ACH-000565	RCM1_LARGE_INTESTINE	HTS002	1	0.162122	10.840679	0.820163	0.497962	0.029841	0.030939	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000565
BRD-K47832606-001-30-1	ACH-000209	SNU1079_BILIARY_TRACT	HTS002	1	0.16796	4.372262	0.568134	0.601762	0.096129	0.105564	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000209
BRD-K47832606-001-30-1	ACH-000927	BT474_BREAST	HTS002	1	0.536892	3.307949	0.326276	0.781048	0.101734	null	floxuridine	DNA synthesis inhibitor	TYMS	oncology	colorectal cancer	OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O	Launched	true	ACH-000927
BRD-K72951360-001-01-4	ACH-000879	MFE296_ENDOMETRIUM	HTS002	1	0.052323	2.445771	0.626228	0.656293	0.296161	0.309853	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000879
BRD-K72951360-001-01-4	ACH-000320	PSN1_PANCREAS	HTS002	1	0.027715	4.411637	0.784023	0.651509	0.308635	0.312651	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000320
BRD-K72951360-001-01-4	ACH-001145	OC316_OVARY	HTS002	1	0.008265	3.272199	0.794123	0.505583	0.079241	0.079646	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-001145
BRD-K72951360-001-01-4	ACH-000873	KYSE270_OESOPHAGUS	HTS002	1	0.006584	2.419384	0.785497	0.59165	0.185201	0.186219	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000873
BRD-K72951360-001-01-4	ACH-000855	KYSE150_OESOPHAGUS	HTS002	1	0.086549	1.969422	0.759049	0.617227	0.171418	0.188786	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000855
BRD-K72951360-001-01-4	ACH-000913	ESS1_ENDOMETRIUM	HTS002	1	0.060678	17.259716	0.39966	0.80946	1.396727	1.407236	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000913
BRD-K72951360-001-01-4	ACH-000558	A172_CENTRAL_NERVOUS_SYSTEM	HTS002	1	-0.013869	2.079351	0.402281	0.826771	1.88962	1.864919	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000558
BRD-K72951360-001-01-4	ACH-000593	BC3C_URINARY_TRACT	HTS002	1	-0.014205	1.236688	0.553545	0.752404	0.943959	0.922817	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000593
BRD-K72951360-001-01-4	ACH-000488	TE11_OESOPHAGUS	HTS002	1	0.000024	2.556876	0.801478	0.630702	0.277716	0.277721	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000488
BRD-K72951360-001-01-4	ACH-000832	CAL27_UPPER_AERODIGESTIVE_TRACT	HTS002	1	0.000425	1.298922	0.729522	0.647558	0.329519	0.329735	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000832
BRD-K72951360-001-01-4	ACH-000781	NCIH2023_LUNG	HTS002	1	0.03628	2.046344	0.57614	0.707443	0.526182	0.545912	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000781

BRD-K47832606-001-30-1

ACH-000921

NCIH1339_LUNG

HTS002

1

0.169494

1.82881

0.790841

0.684057

0.249465

0.312838

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000921

BRD-K47832606-001-30-1

ACH-000954

HEC1A_ENDOMETRIUM

HTS002

1

0.200005

2.659634

0.77066

0.557639

0.046732

0.056628

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000954

BRD-K47832606-001-30-1

ACH-000280

SNU840_OVARY

HTS002

1

0.189876

1.468523

0.947519

0.511865

0.028817

0.039894

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000280

BRD-K47832606-001-30-1

ACH-000012

HCC827_LUNG

HTS002

1

0.177713

2.886328

0.766551

0.526909

0.037609

0.043789

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000012

BRD-K47832606-001-30-1

ACH-000098

GAMG_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.349984

3.49056

0.351852

0.716399

0.144961

0.204661

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000098

BRD-K47832606-001-30-1

ACH-000589

NCIH1437_LUNG

HTS002

1

0.21324

1.239762

0.851529

0.520466

0.026811

0.041982

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000589

BRD-K47832606-001-30-1

ACH-000738

GB1_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.260991

2.110599

0.554954

0.696951

0.186989

0.265274

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000738

BRD-K47832606-001-30-1

ACH-000837

NCIH322_LUNG

HTS002

1

0.186471

2.270251

0.779305

0.573366

0.061638

0.075706

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000837

BRD-K47832606-001-30-1

ACH-000967

SNUC2A_LARGE_INTESTINE

HTS002

1

0.36318

4.146739

0.643656

0.651701

0.049543

0.067718

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000967

BRD-K47832606-001-30-1

ACH-000662

CORL23_LUNG

HTS002

1

0.325649

2.242026

0.536406

0.640754

0.056865

0.090976

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000662

BRD-K47832606-001-30-1

ACH-000427

NCIN87_STOMACH

HTS002

1

0.985824

0.724332

-0.040625

0.992083

0.042747

null

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000427

BRD-K47832606-001-30-1

ACH-000774

RERFLCAD2_LUNG

HTS002

1

0.404402

2.458731

0.320509

0.861681

1.051848

2.061513

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000774

BRD-K47832606-001-30-1

ACH-000624

HCC1806_BREAST

HTS002

1

0.131288

1.982768

0.781656

0.40447

0.012893

0.015034

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000624

BRD-K47832606-001-30-1

ACH-000888

NCIH1793_LUNG

HTS002

1

0.62223

1.790772

0.452514

0.843431

0.179255

null

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000888

BRD-K47832606-001-30-1

ACH-000449

MESSA_SOFT_TISSUE

HTS002

1

0.121416

3.094364

0.70735

0.537901

0.060727

0.066439

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000449

BRD-K47832606-001-30-1

ACH-000587

NCIH1975_LUNG

HTS002

1

0.189755

2.948271

0.800872

0.538989

0.040002

0.047031

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000587

BRD-K47832606-001-30-1

ACH-000404

K029AX_SKIN

HTS002

1

0.242322

4.206711

0.421293

0.672698

0.151165

0.176965

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000404

BRD-K47832606-001-30-1

ACH-000813

T3M10_LUNG

HTS002

1

0.110118

1.884296

0.683038

0.505854

0.045677

0.052123

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000813

BRD-K47832606-001-30-1

ACH-000311

NCIH2122_LUNG

HTS002

1

0.19299

3.066034

0.626347

0.556452

0.048269

0.056592

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000311

BRD-K47832606-001-30-1

ACH-000849

MDAMB468_BREAST

HTS002

1

0.302233

4.096219

0.741446

0.652405

0.079537

0.099749

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000849

BRD-K47832606-001-30-1

ACH-000868

HCC1195_LUNG

HTS002

1

0.362891

4.972981

0.565683

0.626406

0.033783

0.043822

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000868

BRD-K47832606-001-30-1

ACH-000978

EN_ENDOMETRIUM

HTS002

1

1.567675

-0.476239

0.123242

1.21921

0.019975

null

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000978

BRD-K47832606-001-30-1

ACH-000408

TE5_OESOPHAGUS

HTS002

1

0.441971

4.047398

0.663495

0.747628

0.124164

0.211393

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000408

BRD-K47832606-001-30-1

ACH-000344

SNU668_STOMACH

HTS002

1

0.411234

1.656151

0.689852

0.672819

0.045482

0.129163

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000344

BRD-K47832606-001-30-1

ACH-000161

CORL105_LUNG

HTS002

1

0.290168

0.953168

0.374065

0.746427

0.323843

0.805307

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000161

BRD-K47832606-001-30-1

ACH-000835

GCT_SOFT_TISSUE

HTS002

1

0.29838

2.329911

0.61829

0.668198

0.101617

0.150058

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000835

BRD-K47832606-001-30-1

ACH-000819

LN18_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.128059

4.740864

0.94249

0.536027

0.057206

0.06089

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000819

BRD-K47832606-001-30-1

ACH-000062

RERFLCMS_LUNG

HTS002

1

0.107584

3.25189

0.662667

0.579299

0.103096

0.111071

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000062

BRD-K47832606-001-30-1

ACH-000473

RT112_URINARY_TRACT

HTS002

1

0.06352

12.698418

0.824702

0.462981

0.038305

0.038717

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000473

BRD-K47832606-001-30-1

ACH-000176

LOUNH91_LUNG

HTS002

1

0.11798

2.871783

0.880034

0.488746

0.03607

0.039614

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000176

BRD-K47832606-001-30-1

ACH-000445

KNS60_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.196759

3.457669

0.814226

0.572092

0.056867

0.065716

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000445

BRD-K47832606-001-30-1

ACH-000331

ISTMES2_PLEURA

HTS002

1

0.358737

12.070301

0.372135

0.680629

0.079629

0.088419

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000331

BRD-K47832606-001-30-1

ACH-000163

SW579_THYROID

HTS002

1

0.164713

1.170134

0.428557

0.540462

0.047849

0.067328

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000163

BRD-K47832606-001-30-1

ACH-000768

MDAMB231_BREAST

HTS002

1

0.239316

1.960808

0.578707

0.621872

0.080363

0.112024

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000768

BRD-K47832606-001-30-1

null

HTS002

1

0.05041

0.561882

0.437837

0.303972

0.005249

0.006341

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

false

ACH-001078_FAILED_STR

BRD-K47832606-001-30-1

ACH-000778

HSC3_UPPER_AERODIGESTIVE_TRACT

HTS002

1

0.074189

2.661799

0.86234

0.454647

0.032921

0.034968

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000778

BRD-K47832606-001-30-1

ACH-000881

MELJUSO_SKIN

HTS002

1

0.196763

3.503941

0.732898

0.614442

0.094853

0.109404

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000881

BRD-K47832606-001-30-1

ACH-000521

NCIH2030_LUNG

HTS002

1

0.211607

3.173448

0.713728

0.590132

0.064419

0.076616

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000521

BRD-K47832606-001-30-1

ACH-000696

OVCAR8_OVARY

HTS002

1

0.161941

1.125809

0.688106

0.608008

0.107136

0.151677

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000696

BRD-K47832606-001-30-1

ACH-000972

HEC151_ENDOMETRIUM

HTS002

1

0.276732

2.204517

0.762872

0.617231

0.058834

0.084812

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000972

BRD-K47832606-001-30-1

ACH-000242

RT4_URINARY_TRACT

HTS002

1

0.289187

2.207249

0.458751

0.587009

0.035591

0.052634

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000242

BRD-K47832606-001-30-1

ACH-000087

SKES1_BONE

HTS002

1

0.030887

1.886249

0.469147

0.478134

0.053765

0.055613

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000087

BRD-K47832606-001-30-1

ACH-000926

HT55_LARGE_INTESTINE

HTS002

1

0.448312

3.259429

0.579317

0.70061

0.051632

0.103585

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000926

BRD-K47832606-001-30-1

ACH-000356

MKN45_STOMACH

HTS002

1

0.084907

2.797742

0.756918

0.481494

0.04093

0.043745

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000356

BRD-K47832606-001-30-1

ACH-000625

HEP3B217_LIVER

HTS002

1

0.246606

1.206595

0.608001

0.633831

0.089541

0.157273

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000625

BRD-K47832606-001-30-1

ACH-000613

HOS_BONE

HTS002

1

0.138001

4.089765

0.553498

0.611932

0.126673

0.137082

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000613

BRD-K47832606-001-30-1

ACH-000976

HUCCT1_BILIARY_TRACT

HTS002

1

0.271249

3.448229

0.757872

0.588434

0.041676

0.052284

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000976

BRD-K47832606-001-30-1

ACH-001075

NCIH292_LUNG

HTS002

1

0.223213

1.474779

0.671783

0.50024

0.019356

0.028904

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-001075

BRD-K47832606-001-30-1

ACH-000261

RERFLCAI_LUNG

HTS002

1

0.143605

1.705271

0.770959

0.629339

0.150004

0.182949

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000261

BRD-K47832606-001-30-1

ACH-000957

LS180_LARGE_INTESTINE

HTS002

1

0.254328

1.808122

0.715066

0.507687

0.016478

0.024411

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000957

BRD-K47832606-001-30-1

ACH-000099

SIMA_AUTONOMIC_GANGLIA

HTS002

1

0.193772

3.632987

0.614956

0.534736

0.036975

0.042317

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000099

BRD-K47832606-001-30-1

ACH-000783

CAMA1_BREAST

HTS002

1

1.621309

-1.298574

-0.012204

1.200247

0.013745

null

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000783

BRD-K47832606-001-30-1

ACH-000573

MDAMB436_BREAST

HTS002

1

0.371764

14.776771

0.784738

0.689129

0.082143

0.090067

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000573

BRD-K47832606-001-30-1

ACH-000852

NCIH1435_LUNG

HTS002

1

0.56816

3.68613

0.354571

0.883621

0.731531

null

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000852

BRD-K47832606-001-30-1

ACH-000461

SNU1196_BILIARY_TRACT

HTS002

1

0.331582

5.032273

0.485674

0.709706

0.1478

0.183479

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000461

BRD-K47832606-001-30-1

ACH-000420

SNU449_LIVER

HTS002

1

0.375142

5.679479

0.516762

0.73405

0.160794

0.205288

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000420

BRD-K47832606-001-30-1

ACH-000694

TE9_OESOPHAGUS

HTS002

1

0.225925

4.221378

0.517611

0.635029

0.103021

0.118789

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000694

BRD-K47832606-001-30-1

ACH-000528

ABC1_LUNG

HTS002

1

0.393977

4.296893

0.690018

0.708719

0.094268

0.135246

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000528

BRD-K47832606-001-30-1

ACH-000845

NCIH1373_LUNG

HTS002

1

0.304119

2.175101

0.769603

0.644042

0.06986

0.107483

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000845

BRD-K47832606-001-30-1

ACH-000563

EBC1_LUNG

HTS002

1

0.083177

12.905709

0.846091

0.471026

0.037019

0.037545

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000563

BRD-K47832606-001-30-1

ACH-000665

SKMES1_LUNG

HTS002

1

0.216734

2.1144

0.848133

0.575609

0.052061

0.068112

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000665

BRD-K47832606-001-30-1

ACH-000467

HCC56_LARGE_INTESTINE

HTS002

1

0.078884

4.517785

0.761892

0.336164

0.009177

0.009533

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000467

BRD-K47832606-001-30-1

ACH-000201

A204_SOFT_TISSUE

HTS002

1

0.161277

2.014529

0.722435

0.541032

0.049402

0.059937

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000201

BRD-K47832606-001-30-1

ACH-000296

OUMS23_LARGE_INTESTINE

HTS002

1

0.440999

2.476938

0.500134

0.774147

0.19827

0.469848

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000296

BRD-K47832606-001-30-1

ACH-000189

RCC10RGB_KIDNEY

HTS002

1

0.207143

1.580282

0.761001

0.595156

0.070472

0.09886

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000189

BRD-K47832606-001-30-1

ACH-000791

RERFLCAD1_LUNG

HTS002

1

0.292718

6.46605

0.653089

0.671678

0.110574

0.126706

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000791

BRD-K47832606-001-30-1

ACH-000367

NCIH226_LUNG

HTS002

1

0.258068

3.407205

0.809815

0.641351

0.091781

0.113576

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000367

BRD-K47832606-001-30-1

ACH-001190

SKMEL2_SKIN

HTS002

1

0.374845

9.348433

0.460362

0.688212

0.079088

0.091718

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-001190

BRD-K47832606-001-30-1

ACH-000244

DKMG_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.280163

3.83528

0.784052

0.605943

0.049307

0.061089

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000244

BRD-K47832606-001-30-1

ACH-000713

CAOV3_OVARY

HTS002

1

0.0616

9.608751

0.778583

0.55478

0.100111

0.10149

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000713

BRD-K47832606-001-30-1

ACH-000672

IALM_LUNG

HTS002

1

0.322105

4.114544

0.439721

0.690545

0.119163

0.153186

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000672

BRD-K47832606-001-30-1

ACH-000875

NCIH2347_LUNG

HTS002

1

0.169215

0.698842

0.556681

0.620551

0.122471

0.221198

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000875

BRD-K47832606-001-30-1

ACH-000423

SKMEL3_SKIN

HTS002

1

0.585987

4.551335

0.490775

0.809744

0.115691

null

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000423

BRD-K47832606-001-30-1

ACH-000553

SQ1_LUNG

HTS002

1

0.40791

4.88194

0.516194

0.718773

0.0996

0.140852

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000553

BRD-K47832606-001-30-1

ACH-000834

UMUC1_URINARY_TRACT

HTS002

1

0.119878

1.820252

0.718027

0.418062

0.016323

0.018976

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000834

BRD-K47832606-001-30-1

ACH-000252

LS1034_LARGE_INTESTINE

HTS002

1

0.513032

3.974213

0.306433

0.74386

0.060709

null

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000252

BRD-K47832606-001-30-1

ACH-000123

COV434_OVARY

HTS002

1

0.026299

0.579829

0.523142

0.439563

0.034051

0.037376

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000123

BRD-K47832606-001-30-1

ACH-000329

CCFSTTG1_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.232952

1.495068

0.511267

0.62411

0.086058

0.130911

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000329

BRD-K47832606-001-30-1

ACH-000717

COLO680N_OESOPHAGUS

HTS002

1

0.215787

1.49487

0.702824

0.624773

0.0963

0.140521

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000717

BRD-K47832606-001-30-1

ACH-000669

SW900_LUNG

HTS002

1

0.222897

1.103438

0.475873

0.508519

0.021245

0.036271

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000669

BRD-K47832606-001-30-1

ACH-000764

SH10TC_STOMACH

HTS002

1

0.232884

1.690393

0.8222

0.595064

0.059603

0.086365

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000764

BRD-K47832606-001-30-1

ACH-000288

BT549_BREAST

HTS002

1

0.050668

1.127577

0.762202

0.438258

0.031796

0.034956

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000288

BRD-K47832606-001-30-1

ACH-000415

BICR6_UPPER_AERODIGESTIVE_TRACT

HTS002

1

0.111429

1.250427

0.417703

0.50168

0.043172

0.052817

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000415

BRD-K47832606-001-30-1

ACH-000228

BICR31_UPPER_AERODIGESTIVE_TRACT

HTS002

1

0.306331

5.717314

0.71968

0.664541

0.0916

0.108129

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000228

BRD-K47832606-001-30-1

ACH-000977

LNCAPCLONEFGC_PROSTATE

HTS002

1

0.128318

3.397889

0.803044

0.61664

0.140127

0.152907

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000977

BRD-K47832606-001-30-1

ACH-000397

TEN_ENDOMETRIUM

HTS002

1

0.405271

1.231733

0.279145

0.734059

0.130819

0.504931

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000397

BRD-K47832606-001-30-1

ACH-000565

RCM1_LARGE_INTESTINE

HTS002

1

0.162122

10.840679

0.820163

0.497962

0.029841

0.030939

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000565

BRD-K47832606-001-30-1

ACH-000209

SNU1079_BILIARY_TRACT

HTS002

1

0.16796

4.372262

0.568134

0.601762

0.096129

0.105564

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000209

BRD-K47832606-001-30-1

ACH-000927

BT474_BREAST

HTS002

1

0.536892

3.307949

0.326276

0.781048

0.101734

null

floxuridine

DNA synthesis inhibitor

TYMS

oncology

colorectal cancer

OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O

Launched

true

ACH-000927

BRD-K72951360-001-01-4

ACH-000879

MFE296_ENDOMETRIUM

HTS002

1

0.052323

2.445771

0.626228

0.656293

0.296161

0.309853

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000879

BRD-K72951360-001-01-4

ACH-000320

PSN1_PANCREAS

HTS002

1

0.027715

4.411637

0.784023

0.651509

0.308635

0.312651

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000320

BRD-K72951360-001-01-4

ACH-001145

OC316_OVARY

HTS002

1

0.008265

3.272199

0.794123

0.505583

0.079241

0.079646

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-001145

BRD-K72951360-001-01-4

ACH-000873

KYSE270_OESOPHAGUS

HTS002

1

0.006584

2.419384

0.785497

0.59165

0.185201

0.186219

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000873

BRD-K72951360-001-01-4

ACH-000855

KYSE150_OESOPHAGUS

HTS002

1

0.086549

1.969422

0.759049

0.617227

0.171418

0.188786

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000855

BRD-K72951360-001-01-4

ACH-000913

ESS1_ENDOMETRIUM

HTS002

1

0.060678

17.259716

0.39966

0.80946

1.396727

1.407236

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000913

BRD-K72951360-001-01-4

ACH-000558

A172_CENTRAL_NERVOUS_SYSTEM

HTS002

1

-0.013869

2.079351

0.402281

0.826771

1.88962

1.864919

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000558

BRD-K72951360-001-01-4

ACH-000593

BC3C_URINARY_TRACT

HTS002

1

-0.014205

1.236688

0.553545

0.752404

0.943959

0.922817

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000593

BRD-K72951360-001-01-4

ACH-000488

TE11_OESOPHAGUS

HTS002

1

0.000024

2.556876

0.801478

0.630702

0.277716

0.277721

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000488

BRD-K72951360-001-01-4

ACH-000832

CAL27_UPPER_AERODIGESTIVE_TRACT

HTS002

1

0.000425

1.298922

0.729522

0.647558

0.329519

0.329735

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000832

BRD-K72951360-001-01-4

ACH-000781

NCIH2023_LUNG

HTS002

1

0.03628

2.046344

0.57614

0.707443

0.526182

0.545912

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000781