donb-hf/secondary-screen-dose-response-curve-parameters

broad_id string	depmap_id string	ccle_name string	screen_id string	upper_limit int64	lower_limit float64	slope float64	r2 float64	auc float64	ec50 float64	ic50 float64	name string	moa string	target string	disease.area string	indication string	smiles string	phase string	passed_str_profiling bool	row_name string
BRD-K72951360-001-01-4	ACH-000622	KNS42_CENTRAL_NERVOUS_SYSTEM	HTS002	1	-0.122324	0.811244	0.638894	0.785485	1.60025	1.221875	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000622
BRD-K72951360-001-01-4	ACH-000403	NCIH747_LARGE_INTESTINE	HTS002	1	0.0595	2.402047	0.400468	0.736716	0.661419	0.697242	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000403
BRD-K72951360-001-01-4	ACH-000141	SNU308_BILIARY_TRACT	HTS002	1	0.179112	4.196418	0.427904	0.750258	0.522191	0.580403	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000141
BRD-K72951360-001-01-4	ACH-000988	MFE319_ENDOMETRIUM	HTS002	1	0.002438	1.699342	0.608474	0.56871	0.150696	0.15113	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000988
BRD-K72951360-001-01-4	ACH-000848	JHH7_LIVER	HTS002	1	0.058381	2.848102	0.752071	0.610693	0.180955	0.189018	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000848
BRD-K72951360-001-01-4	ACH-000785	NCIH2126_LUNG	HTS002	1	0.009459	19.775732	0.419469	0.840841	2.102962	2.104994	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000785
BRD-K72951360-001-01-4	ACH-000544	OE21_OESOPHAGUS	HTS002	1	0.232908	5.715039	0.529477	0.753388	0.441679	0.492895	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000544
BRD-K72951360-001-01-4	ACH-000982	GP2D_LARGE_INTESTINE	HTS002	1	0.012383	2.805971	0.742334	0.522127	0.091366	0.092186	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000982
BRD-K72951360-001-01-4	ACH-000021	NCIH1693_LUNG	HTS002	1	0.070947	17.561774	0.515958	0.735349	0.630191	0.635707	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000021
BRD-K72951360-001-01-4	ACH-000823	KYSE140_OESOPHAGUS	HTS002	1	0.0476	1.071519	0.613777	0.70345	0.505435	0.554898	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000823
BRD-K72951360-001-01-4	ACH-000915	IPC298_SKIN	HTS002	1	0.030392	5.882091	0.82433	0.571402	0.137116	0.138586	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000915
BRD-K72951360-001-01-4	ACH-000984	HEC6_ENDOMETRIUM	HTS002	1	0.007451	8.576784	0.561572	0.58754	0.177283	0.177594	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000984
BRD-K72951360-001-01-4	ACH-000579	UACC257_SKIN	HTS002	1	-0.068744	1.089819	0.59731	0.749197	0.93754	0.833017	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000579
BRD-K72951360-001-01-4	ACH-001306	8305C_THYROID	HTS002	1	0.000592	1.805563	0.798373	0.6982	0.535239	0.53559	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-001306
BRD-K72951360-001-01-4	ACH-000318	TE10_OESOPHAGUS	HTS002	1	-0.018044	1.153142	0.578202	0.77213	1.175472	1.139883	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000318
BRD-K72951360-001-01-4	ACH-000840	HCC366_LUNG	HTS002	1	-0.040044	1.042154	0.762419	0.694658	0.539802	0.501336	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000840
BRD-K72951360-001-01-4	ACH-000503	BICR16_UPPER_AERODIGESTIVE_TRACT	HTS002	1	0.05509	3.645626	0.225858	0.709621	0.506839	0.523331	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000503
BRD-K72951360-001-01-4	ACH-000726	TE14_OESOPHAGUS	HTS002	1	0.018116	3.945231	0.553415	0.603859	0.199384	0.201258	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000726
BRD-K72951360-001-01-4	ACH-000919	IM95_STOMACH	HTS002	1	0.098286	7.066955	0.564054	0.616736	0.161697	0.166783	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000919
BRD-K72951360-001-01-4	ACH-000188	SCC25_UPPER_AERODIGESTIVE_TRACT	HTS002	1	-0.029382	0.859191	0.459959	0.551323	0.130648	0.122247	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000188
BRD-K72951360-001-01-4	ACH-000618	SNU1041_UPPER_AERODIGESTIVE_TRACT	HTS002	1	0.081068	1.778906	0.770784	0.689458	0.377134	0.416566	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000618
BRD-K72951360-001-01-4	ACH-000822	SKMEL24_SKIN	HTS002	1	-0.040578	0.972364	0.703065	0.674644	0.445936	0.411549	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000822
BRD-K72951360-001-01-4	ACH-000292	NCIH841_LUNG	HTS002	1	0.035592	4.60369	0.878423	0.563588	0.12385	0.125853	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000292
BRD-K72951360-001-01-4	ACH-000827	WM793_SKIN	HTS002	1	0.000437	0.99257	0.746413	0.597391	0.204285	0.204464	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000827
BRD-K72951360-001-01-4	ACH-000411	769P_KIDNEY	HTS002	1	0.001549	1.055522	0.765693	0.625157	0.266689	0.267474	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000411
BRD-K72951360-001-01-4	ACH-000139	PANC0327_PANCREAS	HTS002	1	0.024127	6.356673	0.426203	0.583281	0.158616	0.159855	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000139
BRD-K72951360-001-01-4	ACH-000569	ISTMES1_PLEURA	HTS002	1	-0.011302	0.553297	0.619571	0.560699	0.153779	0.147691	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000569
BRD-K72951360-001-01-4	ACH-000741	UBLC1_URINARY_TRACT	HTS002	1	0.00685	2.242985	0.615165	0.541952	0.113837	0.114539	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000741
BRD-K72951360-001-01-4	ACH-000278	COV362_OVARY	HTS002	1	0.04175	1.698786	0.707518	0.55672	0.112337	0.118253	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000278
BRD-K72951360-001-01-4	ACH-000425	UACC62_SKIN	HTS002	1	0.000117	1.331958	0.893303	0.58431	0.177519	0.17755	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000425
BRD-K72951360-001-01-4	ACH-000013	ONCODG1_OVARY	HTS002	1	0.029705	4.633912	0.59958	0.563307	0.126837	0.128525	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000013
BRD-K72951360-001-01-4	ACH-000231	KALS1_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.000689	1.075566	0.763501	0.613975	0.239092	0.239399	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000231
BRD-K72951360-001-01-4	ACH-000730	SKMEL5_SKIN	HTS002	1	-0.00004	1.301401	0.539757	0.626062	0.267254	0.267238	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000730
BRD-K72951360-001-01-4	ACH-000500	SNU46_UPPER_AERODIGESTIVE_TRACT	HTS002	1	0.00172	29.248443	0.454661	0.846149	2.241239	2.241503	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000500
BRD-K72951360-001-01-4	ACH-000222	ASPC1_PANCREAS	HTS002	1	0.00036	2.328774	0.693413	0.715019	0.629263	0.629458	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000222
BRD-K72951360-001-01-4	ACH-000477	MALME3M_SKIN	HTS002	1	-0.135639	0.991395	0.328265	0.795114	1.592318	1.249926	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000477
BRD-K72951360-001-01-4	ACH-000223	HCC1937_BREAST	HTS002	1	0.053799	1.733291	0.603604	0.720998	0.574212	0.61319	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000223
BRD-K72951360-001-01-4	ACH-000495	TUHR4TKB_KIDNEY	HTS002	1	0.068918	1.356692	0.735965	0.606998	0.166802	0.186071	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000495
BRD-K72951360-001-01-4	ACH-000434	NCIH1915_LUNG	HTS002	1	0.000491	1.007166	0.599637	0.673167	0.43584	0.436265	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000434
BRD-K72951360-001-01-4	ACH-000744	NCIH1623_LUNG	HTS002	1	0.059676	5.157024	0.723261	0.565606	0.113004	0.115823	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000744
BRD-K72951360-001-01-4	ACH-000107	CAPAN2_PANCREAS	HTS002	1	-0.057667	1.292382	0.639316	0.786281	1.327819	1.220278	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000107
BRD-K72951360-001-01-4	ACH-000516	CAL78_BONE	HTS002	1	0.092981	7.951168	0.410705	0.692879	0.374087	0.383893	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000516
BRD-K72951360-001-01-4	ACH-000182	SNU869_BILIARY_TRACT	HTS002	1	0.01877	2.143185	0.665232	0.606398	0.203943	0.207617	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000182
BRD-K72951360-001-01-4	ACH-000898	SNU719_STOMACH	HTS002	1	0.006796	11.769948	0.717863	0.707691	0.574984	0.575653	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000898
BRD-K72951360-001-01-4	ACH-000040	U118MG_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.005698	1.832421	0.359927	0.752897	0.902619	0.908282	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000040
BRD-K72951360-001-01-4	ACH-000808	HUH28_BILIARY_TRACT	HTS002	1	0.000386	1.195024	0.703835	0.663891	0.389239	0.389491	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000808
BRD-K72951360-001-01-4	ACH-000447	NCIH2228_LUNG	HTS002	1	0.084405	6.449414	0.655339	0.703795	0.4331	0.445696	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000447
BRD-K72951360-001-01-4	ACH-000715	SNU1214_UPPER_AERODIGESTIVE_TRACT	HTS002	1	0.00575	8.014464	0.560095	0.708269	0.579977	0.580814	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000715
BRD-K72951360-001-01-4	ACH-000186	NCIH2444_LUNG	HTS002	1	0.027104	16.053464	0.297406	0.580832	0.152838	0.15337	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000186
BRD-K72951360-001-01-4	ACH-000542	HEYA8_OVARY	HTS002	1	0.016033	0.866972	0.669277	0.519471	0.087767	0.091129	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000542
BRD-K72951360-001-01-4	ACH-000943	RKO_LARGE_INTESTINE	HTS002	1	0.000724	1.28148	0.639263	0.595877	0.198445	0.198669	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000943
BRD-K72951360-001-01-4	ACH-000174	CAL62_THYROID	HTS002	1	0.014288	1.612489	0.92999	0.620853	0.239656	0.244004	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000174
BRD-K72951360-001-01-4	ACH-000393	HLF_LIVER	HTS002	1	0.007845	2.898708	0.56171	0.625802	0.257337	0.258745	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000393
BRD-K72951360-001-01-4	ACH-000018	T24_URINARY_TRACT	HTS002	1	-0.053897	1.064534	0.823688	0.779137	1.297195	1.178261	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000018
BRD-K72951360-001-01-4	ACH-000906	ES2_OVARY	HTS002	1	0.063736	6.093192	0.88807	0.69113	0.407075	0.416288	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000906
BRD-K72951360-001-01-4	ACH-000784	KYSE70_OESOPHAGUS	HTS002	1	0.122258	1.233977	0.645328	0.661685	0.239263	0.300303	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000784
BRD-K72951360-001-01-4	ACH-000265	KP4_PANCREAS	HTS002	1	0.128518	2.474086	0.657133	0.578684	0.091737	0.103443	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000265
BRD-K72951360-001-01-4	ACH-000880	AGS_STOMACH	HTS002	1	0.086875	2.307433	0.903315	0.564577	0.097804	0.106237	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000880
BRD-K72951360-001-01-4	ACH-000961	ISHIKAWAHERAKLIO02ER_ENDOMETRIUM	HTS002	1	0.000926	1.208224	0.89977	0.605413	0.218134	0.218469	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000961
BRD-K72951360-001-01-4	ACH-000847	HGC27_STOMACH	HTS002	1	-0.000843	5.821328	0.665268	0.534515	0.109206	0.109175	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000847
BRD-K72951360-001-01-4	ACH-000896	647V_URINARY_TRACT	HTS002	1	0.003342	2.259444	0.697067	0.613813	0.232822	0.233514	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000896
BRD-K72951360-001-01-4	ACH-000685	L33_PANCREAS	HTS002	1	0.004882	1.721817	0.494727	0.639048	0.296424	0.298118	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000685
BRD-K72951360-001-01-4	ACH-000376	SF295_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.045195	1.108031	0.368141	0.702013	0.49933	0.543902	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000376
BRD-K72951360-001-01-4	ACH-000428	UO31_KIDNEY	HTS002	1	0.002845	26.026289	0.367337	0.934419	5.282315	5.283473	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000428
BRD-K72951360-001-01-4	ACH-000749	DMS273_LUNG	HTS002	1	0.011519	1.471078	0.675995	0.559612	0.132675	0.134794	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000749
BRD-K72951360-001-01-4	ACH-000572	G361_SKIN	HTS002	1	-0.038514	1.078122	0.506626	0.704564	0.593464	0.553991	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000572
BRD-K72951360-001-01-4	ACH-000704	OAW42_OVARY	HTS002	1	0.017777	3.210111	0.646415	0.701785	0.525364	0.531322	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000704
BRD-K72951360-001-01-4	ACH-000457	CAL54_KIDNEY	HTS002	1	0.044693	6.770018	0.724812	0.713771	0.546101	0.553707	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000457
BRD-K72951360-001-01-4	ACH-000601	MIAPACA2_PANCREAS	HTS002	1	0.030046	2.551209	0.850087	0.601407	0.185409	0.189968	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000601
BRD-K72951360-001-01-4	ACH-000651	SW620_LARGE_INTESTINE	HTS002	1	0.014421	1.415586	0.863063	0.596627	0.188868	0.192814	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000651
BRD-K72951360-001-01-4	ACH-000361	SKHEP1_LIVER	HTS002	1	0.012405	1.514732	0.928428	0.544918	0.114347	0.116259	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000361
BRD-K72951360-001-01-4	ACH-000842	SW480_LARGE_INTESTINE	HTS002	1	0.022121	2.141384	0.799149	0.621641	0.234115	0.239115	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000842
BRD-K72951360-001-01-4	ACH-000570	YKG1_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.022939	10.929077	0.518764	0.701955	0.51811	0.520341	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000570
BRD-K72951360-001-01-4	ACH-000396	J82_URINARY_TRACT	HTS002	1	-0.000351	11.592757	0.632674	0.700012	0.544156	0.544123	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000396
BRD-K72951360-001-01-4	ACH-000777	KYSE30_OESOPHAGUS	HTS002	1	0.056315	1.828107	0.832213	0.621686	0.204486	0.218299	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000777
BRD-K72951360-001-01-4	ACH-000096	G401_SOFT_TISSUE	HTS002	1	0.018848	1.794451	0.56363	0.47542	0.055805	0.057013	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000096
BRD-K72951360-001-01-4	ACH-000955	SNU407_LARGE_INTESTINE	HTS002	1	0.000276	1.170559	0.242355	0.662718	0.385551	0.385733	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000955
BRD-K72951360-001-01-4	ACH-000940	AN3CA_ENDOMETRIUM	HTS002	1	0.000465	1.463739	0.798345	0.569847	0.153771	0.153869	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000940
BRD-K72951360-001-01-4	ACH-001318	PLCPRF5_LIVER	HTS002	1	0.011983	3.276534	0.778594	0.547976	0.117998	0.118874	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-001318
BRD-K72951360-001-01-4	ACH-000332	YAPC_PANCREAS	HTS002	1	0.01266	5.130449	0.727791	0.699105	0.519566	0.52217	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000332
BRD-K72951360-001-01-4	ACH-000839	SCABER_URINARY_TRACT	HTS002	1	0.006711	2.172983	0.643133	0.652251	0.334702	0.33679	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000839
BRD-K72951360-001-01-4	ACH-000082	G292CLONEA141B1_BONE	HTS002	1	0.303565	4.12332	0.340616	0.686256	0.126299	0.158418	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000082
BRD-K72951360-001-01-4	ACH-000178	HS766T_PANCREAS	HTS002	1	-0.051551	1.555681	0.361949	0.825266	1.924461	1.806823	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000178
BRD-K72951360-001-01-4	ACH-000421	SW837_LARGE_INTESTINE	HTS002	1	-0.01833	0.887726	0.628768	0.612216	0.240348	0.230795	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000421
BRD-K72951360-001-01-4	ACH-000524	KURAMOCHI_OVARY	HTS002	1	0.006601	1.216688	0.582693	0.605747	0.214006	0.216357	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000524
BRD-K72951360-001-01-4	ACH-000469	YH13_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.068035	3.664051	0.518428	0.713499	0.50631	0.52693	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000469
BRD-K72951360-001-01-4	ACH-000153	NCIH2052_PLEURA	HTS002	1	0.044589	4.994042	0.513127	0.719062	0.576433	0.587316	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000153
BRD-K72951360-001-01-4	ACH-000805	COLO679_SKIN	HTS002	1	0.001132	1.242432	0.77844	0.575319	0.162153	0.16245	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000805
BRD-K72951360-001-01-4	ACH-000429	A704_KIDNEY	HTS002	1	1.372071	0.236892	-0.016994	1.144052	0.666505	null	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000429
BRD-K72951360-001-01-4	ACH-000108	KP3_PANCREAS	HTS002	1	0.222759	8.139625	0.606647	0.768526	0.555751	0.59751	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000108
BRD-K72951360-001-01-4	ACH-000939	SKUT1_SOFT_TISSUE	HTS002	1	0.006012	2.583846	0.828772	0.600674	0.20272	0.203671	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000939
BRD-K72951360-001-01-4	ACH-000323	42MGBA_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.01856	2.893702	0.838792	0.61725	0.22721	0.230199	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000323
BRD-K72951360-001-01-4	ACH-000219	A375_SKIN	HTS002	1	0.030407	1.552291	0.822234	0.590087	0.165465	0.17229	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000219
BRD-K72951360-001-01-4	ACH-000903	FTC133_THYROID	HTS002	1	0.028398	8.95165	0.654772	0.58103	0.152291	0.153289	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000903
BRD-K72951360-001-01-4	ACH-000054	HT1080_SOFT_TISSUE	HTS002	1	0.016372	0.809184	0.47202	0.47169	0.053707	0.055963	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000054
BRD-K72951360-001-01-4	ACH-000302	SNU1077_ENDOMETRIUM	HTS002	1	0.012053	9.738165	0.450935	0.70672	0.560936	0.562343	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000302
BRD-K72951360-001-01-4	ACH-000324	JHOC5_OVARY	HTS002	1	0.041258	0.839589	0.468188	0.538423	0.094129	0.104297	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000324
BRD-K72951360-001-01-4	ACH-000164	PANC1_PANCREAS	HTS002	1	0.022995	2.392088	0.506939	0.663719	0.354382	0.361426	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000164
BRD-K72951360-001-01-4	ACH-000549	SNU1076_UPPER_AERODIGESTIVE_TRACT	HTS002	1	0.001825	2.928031	0.752158	0.694553	0.513317	0.513959	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000549
BRD-K72951360-001-01-4	ACH-000650	IGR37_SKIN	HTS002	1	0.029881	2.958423	0.834468	0.687843	0.440485	0.449756	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000650

BRD-K72951360-001-01-4

ACH-000622

KNS42_CENTRAL_NERVOUS_SYSTEM

HTS002

1

-0.122324

0.811244

0.638894

0.785485

1.60025

1.221875

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000622

BRD-K72951360-001-01-4

ACH-000403

NCIH747_LARGE_INTESTINE

HTS002

1

0.0595

2.402047

0.400468

0.736716

0.661419

0.697242

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000403

BRD-K72951360-001-01-4

ACH-000141

SNU308_BILIARY_TRACT

HTS002

1

0.179112

4.196418

0.427904

0.750258

0.522191

0.580403

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000141

BRD-K72951360-001-01-4

ACH-000988

MFE319_ENDOMETRIUM

HTS002

1

0.002438

1.699342

0.608474

0.56871

0.150696

0.15113

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000988

BRD-K72951360-001-01-4

ACH-000848

JHH7_LIVER

HTS002

1

0.058381

2.848102

0.752071

0.610693

0.180955

0.189018

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000848

BRD-K72951360-001-01-4

ACH-000785

NCIH2126_LUNG

HTS002

1

0.009459

19.775732

0.419469

0.840841

2.102962

2.104994

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000785

BRD-K72951360-001-01-4

ACH-000544

OE21_OESOPHAGUS

HTS002

1

0.232908

5.715039

0.529477

0.753388

0.441679

0.492895

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000544

BRD-K72951360-001-01-4

ACH-000982

GP2D_LARGE_INTESTINE

HTS002

1

0.012383

2.805971

0.742334

0.522127

0.091366

0.092186

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000982

BRD-K72951360-001-01-4

ACH-000021

NCIH1693_LUNG

HTS002

1

0.070947

17.561774

0.515958

0.735349

0.630191

0.635707

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000021

BRD-K72951360-001-01-4

ACH-000823

KYSE140_OESOPHAGUS

HTS002

1

0.0476

1.071519

0.613777

0.70345

0.505435

0.554898

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000823

BRD-K72951360-001-01-4

ACH-000915

IPC298_SKIN

HTS002

1

0.030392

5.882091

0.82433

0.571402

0.137116

0.138586

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000915

BRD-K72951360-001-01-4

ACH-000984

HEC6_ENDOMETRIUM

HTS002

1

0.007451

8.576784

0.561572

0.58754

0.177283

0.177594

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000984

BRD-K72951360-001-01-4

ACH-000579

UACC257_SKIN

HTS002

1

-0.068744

1.089819

0.59731

0.749197

0.93754

0.833017

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000579

BRD-K72951360-001-01-4

ACH-001306

8305C_THYROID

HTS002

1

0.000592

1.805563

0.798373

0.6982

0.535239

0.53559

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-001306

BRD-K72951360-001-01-4

ACH-000318

TE10_OESOPHAGUS

HTS002

1

-0.018044

1.153142

0.578202

0.77213

1.175472

1.139883

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000318

BRD-K72951360-001-01-4

ACH-000840

HCC366_LUNG

HTS002

1

-0.040044

1.042154

0.762419

0.694658

0.539802

0.501336

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000840

BRD-K72951360-001-01-4

ACH-000503

BICR16_UPPER_AERODIGESTIVE_TRACT

HTS002

1

0.05509

3.645626

0.225858

0.709621

0.506839

0.523331

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000503

BRD-K72951360-001-01-4

ACH-000726

TE14_OESOPHAGUS

HTS002

1

0.018116

3.945231

0.553415

0.603859

0.199384

0.201258

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000726

BRD-K72951360-001-01-4

ACH-000919

IM95_STOMACH

HTS002

1

0.098286

7.066955

0.564054

0.616736

0.161697

0.166783

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000919

BRD-K72951360-001-01-4

ACH-000188

SCC25_UPPER_AERODIGESTIVE_TRACT

HTS002

1

-0.029382

0.859191

0.459959

0.551323

0.130648

0.122247

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000188

BRD-K72951360-001-01-4

ACH-000618

SNU1041_UPPER_AERODIGESTIVE_TRACT

HTS002

1

0.081068

1.778906

0.770784

0.689458

0.377134

0.416566

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000618

BRD-K72951360-001-01-4

ACH-000822

SKMEL24_SKIN

HTS002

1

-0.040578

0.972364

0.703065

0.674644

0.445936

0.411549

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000822

BRD-K72951360-001-01-4

ACH-000292

NCIH841_LUNG

HTS002

1

0.035592

4.60369

0.878423

0.563588

0.12385

0.125853

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000292

BRD-K72951360-001-01-4

ACH-000827

WM793_SKIN

HTS002

1

0.000437

0.99257

0.746413

0.597391

0.204285

0.204464

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000827

BRD-K72951360-001-01-4

ACH-000411

769P_KIDNEY

HTS002

1

0.001549

1.055522

0.765693

0.625157

0.266689

0.267474

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000411

BRD-K72951360-001-01-4

ACH-000139

PANC0327_PANCREAS

HTS002

1

0.024127

6.356673

0.426203

0.583281

0.158616

0.159855

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000139

BRD-K72951360-001-01-4

ACH-000569

ISTMES1_PLEURA

HTS002

1

-0.011302

0.553297

0.619571

0.560699

0.153779

0.147691

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000569

BRD-K72951360-001-01-4

ACH-000741

UBLC1_URINARY_TRACT

HTS002

1

0.00685

2.242985

0.615165

0.541952

0.113837

0.114539

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000741

BRD-K72951360-001-01-4

ACH-000278

COV362_OVARY

HTS002

1

0.04175

1.698786

0.707518

0.55672

0.112337

0.118253

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000278

BRD-K72951360-001-01-4

ACH-000425

UACC62_SKIN

HTS002

1

0.000117

1.331958

0.893303

0.58431

0.177519

0.17755

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000425

BRD-K72951360-001-01-4

ACH-000013

ONCODG1_OVARY

HTS002

1

0.029705

4.633912

0.59958

0.563307

0.126837

0.128525

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000013

BRD-K72951360-001-01-4

ACH-000231

KALS1_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.000689

1.075566

0.763501

0.613975

0.239092

0.239399

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000231

BRD-K72951360-001-01-4

ACH-000730

SKMEL5_SKIN

HTS002

1

-0.00004

1.301401

0.539757

0.626062

0.267254

0.267238

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000730

BRD-K72951360-001-01-4

ACH-000500

SNU46_UPPER_AERODIGESTIVE_TRACT

HTS002

1

0.00172

29.248443

0.454661

0.846149

2.241239

2.241503

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000500

BRD-K72951360-001-01-4

ACH-000222

ASPC1_PANCREAS

HTS002

1

0.00036

2.328774

0.693413

0.715019

0.629263

0.629458

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000222

BRD-K72951360-001-01-4

ACH-000477

MALME3M_SKIN

HTS002

1

-0.135639

0.991395

0.328265

0.795114

1.592318

1.249926

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000477

BRD-K72951360-001-01-4

ACH-000223

HCC1937_BREAST

HTS002

1

0.053799

1.733291

0.603604

0.720998

0.574212

0.61319

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000223

BRD-K72951360-001-01-4

ACH-000495

TUHR4TKB_KIDNEY

HTS002

1

0.068918

1.356692

0.735965

0.606998

0.166802

0.186071

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000495

BRD-K72951360-001-01-4

ACH-000434

NCIH1915_LUNG

HTS002

1

0.000491

1.007166

0.599637

0.673167

0.43584

0.436265

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000434

BRD-K72951360-001-01-4

ACH-000744

NCIH1623_LUNG

HTS002

1

0.059676

5.157024

0.723261

0.565606

0.113004

0.115823

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000744

BRD-K72951360-001-01-4

ACH-000107

CAPAN2_PANCREAS

HTS002

1

-0.057667

1.292382

0.639316

0.786281

1.327819

1.220278

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000107

BRD-K72951360-001-01-4

ACH-000516

CAL78_BONE

HTS002

1

0.092981

7.951168

0.410705

0.692879

0.374087

0.383893

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000516

BRD-K72951360-001-01-4

ACH-000182

SNU869_BILIARY_TRACT

HTS002

1

0.01877

2.143185

0.665232

0.606398

0.203943

0.207617

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000182

BRD-K72951360-001-01-4

ACH-000898

SNU719_STOMACH

HTS002

1

0.006796

11.769948

0.717863

0.707691

0.574984

0.575653

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000898

BRD-K72951360-001-01-4

ACH-000040

U118MG_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.005698

1.832421

0.359927

0.752897

0.902619

0.908282

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000040

BRD-K72951360-001-01-4

ACH-000808

HUH28_BILIARY_TRACT

HTS002

1

0.000386

1.195024

0.703835

0.663891

0.389239

0.389491

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000808

BRD-K72951360-001-01-4

ACH-000447

NCIH2228_LUNG

HTS002

1

0.084405

6.449414

0.655339

0.703795

0.4331

0.445696

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000447

BRD-K72951360-001-01-4

ACH-000715

SNU1214_UPPER_AERODIGESTIVE_TRACT

HTS002

1

0.00575

8.014464

0.560095

0.708269

0.579977

0.580814

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000715

BRD-K72951360-001-01-4

ACH-000186

NCIH2444_LUNG

HTS002

1

0.027104

16.053464

0.297406

0.580832

0.152838

0.15337

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000186

BRD-K72951360-001-01-4

ACH-000542

HEYA8_OVARY

HTS002

1

0.016033

0.866972

0.669277

0.519471

0.087767

0.091129

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000542

BRD-K72951360-001-01-4

ACH-000943

RKO_LARGE_INTESTINE

HTS002

1

0.000724

1.28148

0.639263

0.595877

0.198445

0.198669

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000943

BRD-K72951360-001-01-4

ACH-000174

CAL62_THYROID

HTS002

1

0.014288

1.612489

0.92999

0.620853

0.239656

0.244004

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000174

BRD-K72951360-001-01-4

ACH-000393

HLF_LIVER

HTS002

1

0.007845

2.898708

0.56171

0.625802

0.257337

0.258745

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000393

BRD-K72951360-001-01-4

ACH-000018

T24_URINARY_TRACT

HTS002

1

-0.053897

1.064534

0.823688

0.779137

1.297195

1.178261

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000018

BRD-K72951360-001-01-4

ACH-000906

ES2_OVARY

HTS002

1

0.063736

6.093192

0.88807

0.69113

0.407075

0.416288

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000906

BRD-K72951360-001-01-4

ACH-000784

KYSE70_OESOPHAGUS

HTS002

1

0.122258

1.233977

0.645328

0.661685

0.239263

0.300303

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000784

BRD-K72951360-001-01-4

ACH-000265

KP4_PANCREAS

HTS002

1

0.128518

2.474086

0.657133

0.578684

0.091737

0.103443

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000265

BRD-K72951360-001-01-4

ACH-000880

AGS_STOMACH

HTS002

1

0.086875

2.307433

0.903315

0.564577

0.097804

0.106237

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000880

BRD-K72951360-001-01-4

ACH-000961

ISHIKAWAHERAKLIO02ER_ENDOMETRIUM

HTS002

1

0.000926

1.208224

0.89977

0.605413

0.218134

0.218469

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000961

BRD-K72951360-001-01-4

ACH-000847

HGC27_STOMACH

HTS002

1

-0.000843

5.821328

0.665268

0.534515

0.109206

0.109175

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000847

BRD-K72951360-001-01-4

ACH-000896

647V_URINARY_TRACT

HTS002

1

0.003342

2.259444

0.697067

0.613813

0.232822

0.233514

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000896

BRD-K72951360-001-01-4

ACH-000685

L33_PANCREAS

HTS002

1

0.004882

1.721817

0.494727

0.639048

0.296424

0.298118

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000685

BRD-K72951360-001-01-4

ACH-000376

SF295_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.045195

1.108031

0.368141

0.702013

0.49933

0.543902

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000376

BRD-K72951360-001-01-4

ACH-000428

UO31_KIDNEY

HTS002

1

0.002845

26.026289

0.367337

0.934419

5.282315

5.283473

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000428

BRD-K72951360-001-01-4

ACH-000749

DMS273_LUNG

HTS002

1

0.011519

1.471078

0.675995

0.559612

0.132675

0.134794

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000749

BRD-K72951360-001-01-4

ACH-000572

G361_SKIN

HTS002

1

-0.038514

1.078122

0.506626

0.704564

0.593464

0.553991

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000572

BRD-K72951360-001-01-4

ACH-000704

OAW42_OVARY

HTS002

1

0.017777

3.210111

0.646415

0.701785

0.525364

0.531322

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000704

BRD-K72951360-001-01-4

ACH-000457

CAL54_KIDNEY

HTS002

1

0.044693

6.770018

0.724812

0.713771

0.546101

0.553707

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000457

BRD-K72951360-001-01-4

ACH-000601

MIAPACA2_PANCREAS

HTS002

1

0.030046

2.551209

0.850087

0.601407

0.185409

0.189968

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000601

BRD-K72951360-001-01-4

ACH-000651

SW620_LARGE_INTESTINE

HTS002

1

0.014421

1.415586

0.863063

0.596627

0.188868

0.192814

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000651

BRD-K72951360-001-01-4

ACH-000361

SKHEP1_LIVER

HTS002

1

0.012405

1.514732

0.928428

0.544918

0.114347

0.116259

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000361

BRD-K72951360-001-01-4

ACH-000842

SW480_LARGE_INTESTINE

HTS002

1

0.022121

2.141384

0.799149

0.621641

0.234115

0.239115

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000842

BRD-K72951360-001-01-4

ACH-000570

YKG1_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.022939

10.929077

0.518764

0.701955

0.51811

0.520341

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000570

BRD-K72951360-001-01-4

ACH-000396

J82_URINARY_TRACT

HTS002

1

-0.000351

11.592757

0.632674

0.700012

0.544156

0.544123

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000396

BRD-K72951360-001-01-4

ACH-000777

KYSE30_OESOPHAGUS

HTS002

1

0.056315

1.828107

0.832213

0.621686

0.204486

0.218299

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000777

BRD-K72951360-001-01-4

ACH-000096

G401_SOFT_TISSUE

HTS002

1

0.018848

1.794451

0.56363

0.47542

0.055805

0.057013

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000096

BRD-K72951360-001-01-4

ACH-000955

SNU407_LARGE_INTESTINE

HTS002

1

0.000276

1.170559

0.242355

0.662718

0.385551

0.385733

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000955

BRD-K72951360-001-01-4

ACH-000940

AN3CA_ENDOMETRIUM

HTS002

1

0.000465

1.463739

0.798345

0.569847

0.153771

0.153869

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000940

BRD-K72951360-001-01-4

ACH-001318

PLCPRF5_LIVER

HTS002

1

0.011983

3.276534

0.778594

0.547976

0.117998

0.118874

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-001318

BRD-K72951360-001-01-4

ACH-000332

YAPC_PANCREAS

HTS002

1

0.01266

5.130449

0.727791

0.699105

0.519566

0.52217

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000332

BRD-K72951360-001-01-4

ACH-000839

SCABER_URINARY_TRACT

HTS002

1

0.006711

2.172983

0.643133

0.652251

0.334702

0.33679

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000839

BRD-K72951360-001-01-4

ACH-000082

G292CLONEA141B1_BONE

HTS002

1

0.303565

4.12332

0.340616

0.686256

0.126299

0.158418

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000082

BRD-K72951360-001-01-4

ACH-000178

HS766T_PANCREAS

HTS002

1

-0.051551

1.555681

0.361949

0.825266

1.924461

1.806823

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000178

BRD-K72951360-001-01-4

ACH-000421

SW837_LARGE_INTESTINE

HTS002

1

-0.01833

0.887726

0.628768

0.612216

0.240348

0.230795

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000421

BRD-K72951360-001-01-4

ACH-000524

KURAMOCHI_OVARY

HTS002

1

0.006601

1.216688

0.582693

0.605747

0.214006

0.216357

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000524

BRD-K72951360-001-01-4

ACH-000469

YH13_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.068035

3.664051

0.518428

0.713499

0.50631

0.52693

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000469

BRD-K72951360-001-01-4

ACH-000153

NCIH2052_PLEURA

HTS002

1

0.044589

4.994042

0.513127

0.719062

0.576433

0.587316

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000153

BRD-K72951360-001-01-4

ACH-000805

COLO679_SKIN

HTS002

1

0.001132

1.242432

0.77844

0.575319

0.162153

0.16245

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000805

BRD-K72951360-001-01-4

ACH-000429

A704_KIDNEY

HTS002

1

1.372071

0.236892

-0.016994

1.144052

0.666505

null

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000429

BRD-K72951360-001-01-4

ACH-000108

KP3_PANCREAS

HTS002

1

0.222759

8.139625

0.606647

0.768526

0.555751

0.59751

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000108

BRD-K72951360-001-01-4

ACH-000939

SKUT1_SOFT_TISSUE

HTS002

1

0.006012

2.583846

0.828772

0.600674

0.20272

0.203671

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000939

BRD-K72951360-001-01-4

ACH-000323

42MGBA_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.01856

2.893702

0.838792

0.61725

0.22721

0.230199

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000323

BRD-K72951360-001-01-4

ACH-000219

A375_SKIN

HTS002

1

0.030407

1.552291

0.822234

0.590087

0.165465

0.17229

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000219

BRD-K72951360-001-01-4

ACH-000903

FTC133_THYROID

HTS002

1

0.028398

8.95165

0.654772

0.58103

0.152291

0.153289

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000903

BRD-K72951360-001-01-4

ACH-000054

HT1080_SOFT_TISSUE

HTS002

1

0.016372

0.809184

0.47202

0.47169

0.053707

0.055963

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000054

BRD-K72951360-001-01-4

ACH-000302

SNU1077_ENDOMETRIUM

HTS002

1

0.012053

9.738165

0.450935

0.70672

0.560936

0.562343

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000302

BRD-K72951360-001-01-4

ACH-000324

JHOC5_OVARY

HTS002

1

0.041258

0.839589

0.468188

0.538423

0.094129

0.104297

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000324

BRD-K72951360-001-01-4

ACH-000164

PANC1_PANCREAS

HTS002

1

0.022995

2.392088

0.506939

0.663719

0.354382

0.361426

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000164

BRD-K72951360-001-01-4

ACH-000549

SNU1076_UPPER_AERODIGESTIVE_TRACT

HTS002

1

0.001825

2.928031

0.752158

0.694553

0.513317

0.513959

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000549

BRD-K72951360-001-01-4

ACH-000650

IGR37_SKIN

HTS002

1

0.029881

2.958423

0.834468

0.687843

0.440485

0.449756

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000650