donb-hf/secondary-screen-dose-response-curve-parameters

broad_id string	depmap_id string	ccle_name string	screen_id string	upper_limit int64	lower_limit float64	slope float64	r2 float64	auc float64	ec50 float64	ic50 float64	name string	moa string	target string	disease.area string	indication string	smiles string	phase string	passed_str_profiling bool	row_name string
BRD-K72951360-001-01-4	ACH-000217	JHH6_LIVER	HTS002	1	0.046976	1.515511	0.609016	0.683949	0.402298	0.429359	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000217
BRD-K72951360-001-01-4	ACH-000463	NCIH460_LUNG	HTS002	1	0.063381	2.159825	0.867688	0.582818	0.132696	0.14129	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000463
BRD-K72951360-001-01-4	ACH-000748	SJSA1_BONE	HTS002	1	0.000167	4.361378	0.323281	0.880728	3.146973	3.147214	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000748
BRD-K72951360-001-01-4	ACH-000788	A2058_SKIN	HTS002	1	0.040456	6.092138	0.846533	0.582057	0.145998	0.148034	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000788
BRD-K72951360-001-01-4	ACH-000545	VMCUB1_URINARY_TRACT	HTS002	1	0.021276	1.237632	0.426773	0.723015	0.659401	0.68298	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000545
BRD-K72951360-001-01-4	ACH-000762	YD38_UPPER_AERODIGESTIVE_TRACT	HTS002	1	-0.000074	3.286509	0.478259	0.643022	0.312998	0.312984	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000762
BRD-K72951360-001-01-4	ACH-000792	BFTC909_KIDNEY	HTS002	1	0.006875	13.320607	0.23389	0.773596	1.09454	1.095679	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000792
BRD-K72951360-001-01-4	ACH-000211	DAOY_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.001896	3.996788	0.709558	0.554757	0.131823	0.131948	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000211
BRD-K72951360-001-01-4	ACH-000936	EFO27_OVARY	HTS002	1	0.057973	6.702278	0.640031	0.709054	0.49931	0.508576	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000936
BRD-K72951360-001-01-4	ACH-000882	IGR1_SKIN	HTS002	1	0.005765	1.521846	0.75393	0.712854	0.612151	0.616833	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000882
BRD-K72951360-001-01-4	ACH-000471	LI7_LIVER	HTS002	1	0.006717	7.387095	0.683157	0.697492	0.520573	0.521527	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000471
BRD-K72951360-001-01-4	ACH-000670	SBC5_LUNG	HTS002	1	0.062729	5.166902	0.905936	0.590438	0.144016	0.147801	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000670
BRD-K72951360-001-01-4	ACH-000048	TOV112D_OVARY	HTS002	1	0.019313	9.194728	0.522011	0.682656	0.43275	0.434608	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000048
BRD-K72951360-001-01-4	ACH-000259	KELLY_AUTONOMIC_GANGLIA	HTS002	1	0.043494	6.00054	0.802583	0.703845	0.49559	0.503164	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000259
BRD-K72951360-001-01-4	ACH-000599	PATU8902_PANCREAS	HTS002	1	0.029488	1.258897	0.727813	0.600395	0.184809	0.193952	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000599
BRD-K72951360-001-01-4	ACH-000716	TT2609C02_THYROID	HTS002	1	0.019181	5.51549	0.598346	0.683554	0.436798	0.439907	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000716
BRD-K72951360-001-01-4	ACH-000347	QGP1_PANCREAS	HTS002	1	0.052597	22.545351	0.467523	0.819964	1.581718	1.589535	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000347
BRD-K72951360-001-01-4	ACH-000566	SW1710_URINARY_TRACT	HTS002	1	0.042073	7.887352	0.827988	0.579034	0.140588	0.142163	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000566
BRD-K72951360-001-01-4	ACH-001016	BECKER_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.034006	1.224501	0.780187	0.635937	0.260316	0.275729	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-001016
BRD-K72951360-001-01-4	ACH-000395	NCIH520_LUNG	HTS002	1	0.05375	1.583592	0.400198	0.741399	0.711831	0.764833	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000395
BRD-K72951360-001-01-4	ACH-000407	SNU685_ENDOMETRIUM	HTS002	1	0.033057	4.573379	0.481857	0.684232	0.420457	0.426792	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000407
BRD-K72951360-001-01-4	ACH-000418	SW1353_BONE	HTS002	1	-0.10787	0.776276	0.222779	0.713228	0.720029	0.559832	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000418
BRD-K72951360-001-01-4	ACH-000008	A101D_SKIN	HTS002	1	0.000366	1.48637	0.793557	0.638068	0.298989	0.299136	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000008
BRD-K72951360-001-01-4	ACH-000191	BHT101_THYROID	HTS002	1	0.009315	1.304799	0.587475	0.595821	0.191567	0.194348	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000191
BRD-K72951360-001-01-4	ACH-000941	HEC1B_ENDOMETRIUM	HTS002	1	0.000308	0.883245	0.660832	0.800637	1.808005	1.809265	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000941
BRD-K72951360-001-01-4	ACH-000532	SNU61_LARGE_INTESTINE	HTS002	1	0.012715	2.708738	0.724585	0.643088	0.299542	0.302405	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000532
BRD-K72951360-001-01-4	ACH-000316	SNU886_LIVER	HTS002	1	0.020556	3.696865	0.7325	0.576343	0.150333	0.15205	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000316
BRD-K72951360-001-01-4	ACH-000677	SW1573_LUNG	HTS002	1	0.000501	1.098112	0.78499	0.582986	0.176	0.176161	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000677
BRD-K72951360-001-01-4	ACH-000375	G402_SOFT_TISSUE	HTS002	1	0.004666	1.350819	0.788718	0.46939	0.056609	0.057003	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000375
BRD-K72951360-001-01-4	ACH-000619	PECAPJ15_UPPER_AERODIGESTIVE_TRACT	HTS002	1	0.037887	11.485273	0.674235	0.585777	0.1533	0.154355	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000619
BRD-K72951360-001-01-4	ACH-000965	RL952_ENDOMETRIUM	HTS002	1	0.035268	1.75361	0.661475	0.553218	0.111763	0.116524	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000965
BRD-K72951360-001-01-4	ACH-000210	CADOES1_BONE	HTS002	1	0.017655	16.630178	0.282553	0.909139	4.075603	4.084422	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000210
BRD-K72951360-001-01-4	ACH-000803	COLO668_LUNG	HTS002	1	0.023947	5.866264	0.210648	0.677961	0.406903	0.410321	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000803
BRD-K72951360-001-01-4	ACH-000007	LS513_LARGE_INTESTINE	HTS002	1	-0.004452	1.155511	0.358937	0.650495	0.34223	0.339614	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000007
BRD-K72951360-001-01-4	ACH-000719	RMGI_OVARY	HTS002	1	0.001776	9.562309	0.686022	0.706593	0.577109	0.577324	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000719
BRD-K72951360-001-01-4	ACH-000484	VMRCRCW_KIDNEY	HTS002	1	0.091023	2.552803	0.553857	0.72554	0.534045	0.577782	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000484
BRD-K72951360-001-01-4	ACH-000433	CAKI1_KIDNEY	HTS002	1	0.028789	3.093996	0.429068	0.701234	0.505314	0.515092	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000433
BRD-K72951360-001-01-4	ACH-000688	OV7_OVARY	HTS002	1	0.038974	12.410009	0.360113	0.850597	2.21216	2.226674	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000688
BRD-K72951360-001-01-4	ACH-000603	BEN_LUNG	HTS002	1	-0.082965	0.963549	0.669076	0.79692	1.648093	1.405358	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000603
BRD-K72951360-001-01-4	ACH-000351	MKN1_STOMACH	HTS002	1	0.007566	1.777806	0.879945	0.486217	0.065791	0.066357	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000351
BRD-K72951360-001-01-4	ACH-000627	LCLC103H_LUNG	HTS002	1	0.00928	1.904093	0.791833	0.614145	0.228444	0.230703	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000627
BRD-K72951360-001-01-4	ACH-000916	NCIH1573_LUNG	HTS002	1	0.052672	1.175617	0.483278	0.642108	0.258534	0.28421	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000916
BRD-K72951360-001-01-4	ACH-000863	DBTRG05MG_CENTRAL_NERVOUS_SYSTEM	HTS002	1	-0.000167	6.459754	0.675051	0.691449	0.500764	0.500738	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000863
BRD-K72951360-001-01-4	ACH-000732	PECAPJ41CLONED2_UPPER_AERODIGESTIVE_TRACT	HTS002	1	0.011182	20.848701	0.814834	0.572969	0.151341	0.151506	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000732
BRD-K72951360-001-01-4	ACH-000066	HCC4006_LUNG	HTS002	1	0.000095	1.189399	0.66148	0.7237	0.709116	0.709229	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000066
BRD-K72951360-001-01-4	ACH-000015	NCIH1581_LUNG	HTS002	1	0.011946	2.224976	0.449567	0.689667	0.474826	0.480015	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000015
BRD-K72951360-001-01-4	null	null	HTS002	1	0.009449	1.642012	0.681388	0.628583	0.26328	0.266357	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	false	ACH-000511_FAILED_STR
BRD-K72951360-001-01-4	ACH-000674	NUGC4_STOMACH	HTS002	1	0.013768	1.860164	0.844056	0.540942	0.109235	0.110887	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000674
BRD-K72951360-001-01-4	ACH-000892	NCIH1563_LUNG	HTS002	1	-0.004558	0.93533	0.871107	0.626698	0.276134	0.273467	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000892
BRD-K72951360-001-01-4	ACH-000909	JHUEM2_ENDOMETRIUM	HTS002	1	0.005907	1.501474	0.972946	0.442714	0.043352	0.043696	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000909
BRD-K72951360-001-01-4	ACH-000237	JHOM1_OVARY	HTS002	1	0.018726	7.714124	0.721911	0.684936	0.443452	0.445652	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000237
BRD-K72951360-001-01-4	ACH-000811	SKOV3_OVARY	HTS002	1	0.021002	3.034191	0.589658	0.671535	0.385493	0.390984	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000811
BRD-K72951360-001-01-4	ACH-000312	SKNBE2_AUTONOMIC_GANGLIA	HTS002	1	0.004768	1.586118	0.604392	0.652158	0.337502	0.339547	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000312
BRD-K72951360-001-01-4	ACH-000390	LUDLU1_LUNG	HTS002	1	0.026034	1.202638	0.472243	0.718685	0.624113	0.652489	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000390
BRD-K72951360-001-01-4	ACH-000901	HCC1359_LUNG	HTS002	1	0.005588	1.682321	0.435003	0.631625	0.275036	0.27688	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000901
BRD-K72951360-001-01-4	ACH-000307	PK1_PANCREAS	HTS002	1	0.004604	1.526795	0.579138	0.632202	0.277935	0.279624	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000307
BRD-K72951360-001-01-4	ACH-000289	SNU466_CENTRAL_NERVOUS_SYSTEM	HTS002	1	-0.133374	0.698056	0.601143	0.700586	0.661419	0.471376	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000289
BRD-K72951360-001-01-4	ACH-000309	SKLU1_LUNG	HTS002	1	0.017286	6.920964	0.485297	0.687968	0.459019	0.461359	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000309
BRD-K72951360-001-01-4	ACH-000733	NCIH1838_LUNG	HTS002	1	0.018115	4.835398	0.527797	0.577536	0.153711	0.154889	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000733
BRD-K72951360-001-01-4	ACH-000268	SNU245_BILIARY_TRACT	HTS002	1	0.171243	6.593828	0.339494	0.76428	0.632858	0.674407	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000268
BRD-K72951360-001-01-4	ACH-000758	MKN74_STOMACH	HTS002	1	0.058141	3.320474	0.300013	0.855213	2.254566	2.340084	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000758
BRD-K72951360-001-01-4	ACH-000693	KYSE180_OESOPHAGUS	HTS002	1	0.047727	4.170814	0.856808	0.697675	0.459214	0.470393	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000693
BRD-K72951360-001-01-4	ACH-000684	KMRC1_KIDNEY	HTS002	1	0.072167	1.512641	0.333475	0.608492	0.166805	0.18491	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000684
BRD-K72951360-001-01-4	ACH-000264	CALU6_LUNG	HTS002	1	0.129862	11.062357	0.809234	0.624458	0.151739	0.155921	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000264
BRD-K72951360-001-01-4	ACH-000027	GOS3_CENTRAL_NERVOUS_SYSTEM	HTS002	1	-0.053066	1.118628	0.634793	0.748471	0.924717	0.844982	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000027
BRD-K72951360-001-01-4	ACH-000671	HUH6_LIVER	HTS002	1	0.042645	7.365177	0.632018	0.598262	0.170406	0.172481	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000671
BRD-K72951360-001-01-4	ACH-000205	PK59_PANCREAS	HTS002	1	0.028413	1.712142	0.716764	0.573884	0.14184	0.14677	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000205
BRD-K72951360-001-01-4	ACH-000720	TCCSUP_URINARY_TRACT	HTS002	1	0.055462	8.98435	0.509636	0.712664	0.522322	0.529202	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000720
BRD-K72951360-001-01-4	ACH-000814	HS939T_SKIN	HTS002	1	0.00014	11.083271	0.5998	0.700357	0.545757	0.545771	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000814
BRD-K72951360-001-01-4	ACH-000885	TOV21G_OVARY	HTS002	1	0.008438	1.404687	0.807313	0.429879	0.03767	0.038129	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000885
BRD-K72951360-001-01-4	ACH-000663	OVTOKO_OVARY	HTS002	1	0.111766	4.811852	0.469645	0.736085	0.559492	0.589696	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000663
BRD-K72951360-001-01-4	ACH-000647	TE1_OESOPHAGUS	HTS002	1	0.002597	1.789963	0.618302	0.644014	0.31355	0.314463	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000647
BRD-K72951360-001-01-4	ACH-000243	DANG_PANCREAS	HTS002	1	0.013551	2.157034	0.55308	0.602428	0.200211	0.202778	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000243
BRD-K72951360-001-01-4	ACH-000255	LMSU_STOMACH	HTS002	1	0.000345	1.500957	0.618506	0.567833	0.150832	0.150901	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000255
BRD-K72951360-001-01-4	ACH-000335	MSTO211H_PLEURA	HTS002	1	-0.0001	1.11445	0.706476	0.516481	0.091806	0.09179	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000335
BRD-K72951360-001-01-4	ACH-000147	T47D_BREAST	HTS002	1	0.026436	1.412009	0.579044	0.567006	0.133712	0.138956	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000147
BRD-K72951360-001-01-4	ACH-000090	PC3_PROSTATE	HTS002	1	0.127461	2.783892	0.759419	0.634286	0.171228	0.190318	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000090
BRD-K72951360-001-01-4	ACH-000171	VMRCRCZ_KIDNEY	HTS002	1	0.033955	5.433957	0.502877	0.699	0.486262	0.492596	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000171
BRD-K72951360-001-01-4	ACH-000614	RVH421_SKIN	HTS002	1	0.002889	1.306429	0.685826	0.612496	0.231439	0.232468	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000614
BRD-K72951360-001-01-4	ACH-000132	JHOS2_OVARY	HTS002	1	0.139144	7.716213	0.534213	0.648729	0.190682	0.198914	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000132
BRD-K72951360-001-01-4	ACH-000274	HS852T_SKIN	HTS002	1	-0.031499	2.660107	0.676001	0.888525	3.464595	3.385933	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000274
BRD-K72951360-001-01-4	null	null	HTS002	1	0.000837	1.525819	0.768861	0.658275	0.363418	0.363817	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	false	ACH-000807_FAILED_STR
BRD-K72951360-001-01-4	ACH-000810	SKMEL30_SKIN	HTS002	1	0.004688	1.650798	0.563861	0.713819	0.617829	0.621365	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000810
BRD-K72951360-001-01-4	ACH-000343	NCIH522_LUNG	HTS002	1	0.095803	7.68532	0.410104	0.724083	0.51756	0.532084	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000343
BRD-K72951360-001-01-4	ACH-000022	PATU8988S_PANCREAS	HTS002	1	0.436604	13.146116	0.274374	0.865521	0.986377	1.154168	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000022
BRD-K72951360-001-01-4	ACH-000192	MFE280_ENDOMETRIUM	HTS002	1	0.005181	1.685207	0.647637	0.49759	0.074403	0.074864	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000192
BRD-K72951360-001-01-4	null	null	HTS002	1	0.205677	1.912581	0.607508	0.694702	0.240084	0.316735	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	false	ACH-000409_FAILED_STR
BRD-K72951360-001-01-4	ACH-000959	SNUC4_LARGE_INTESTINE	HTS002	1	0.105223	2.210771	0.824859	0.658465	0.24627	0.27405	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000959
BRD-K72951360-001-01-4	null	null	HTS002	1	0.012142	2.049047	0.801491	0.65539	0.33886	0.34295	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	false	ACH-000028_FAILED_STR
BRD-K72951360-001-01-4	ACH-000637	KYSE520_OESOPHAGUS	HTS002	1	-0.02858	0.907459	0.766682	0.645325	0.335088	0.315178	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000637
BRD-K72951360-001-01-4	ACH-000968	COLO792_SKIN	HTS002	1	0.006345	14.866391	0.488708	0.790379	1.290995	1.292105	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000968
BRD-K72951360-001-01-4	ACH-000155	SW1990_PANCREAS	HTS002	1	0.066093	1.674886	0.784983	0.630623	0.215538	0.234578	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000155
BRD-K72951360-001-01-4	ACH-000133	HS729_SOFT_TISSUE	HTS002	1	0.008802	3.884325	0.367492	0.664597	0.3749	0.376619	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000133
BRD-K72951360-001-01-4	ACH-000605	TE6_OESOPHAGUS	HTS002	1	0.074362	1.98571	0.684519	0.598914	0.149247	0.161853	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000605
BRD-K72951360-001-01-4	ACH-000775	NCIH727_LUNG	HTS002	1	0.120583	1.584194	0.082699	0.883383	3.015649	3.58952	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000775
BRD-K72951360-001-01-4	ACH-000042	PANC0203_PANCREAS	HTS002	1	0.054245	4.195355	0.793598	0.688656	0.40983	0.421203	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000042
BRD-K72951360-001-01-4	ACH-000860	NCIH358_LUNG	HTS002	1	0.005277	1.350081	0.642883	0.618255	0.242462	0.244375	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000860
BRD-K72951360-001-01-4	ACH-000994	HEC59_ENDOMETRIUM	HTS002	1	-0.003214	1.429226	0.849271	0.657423	0.362108	0.360488	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000994
BRD-K72951360-001-01-4	ACH-000277	HCC1419_BREAST	HTS002	1	-0.121042	0.848794	0.520795	0.754034	1.083226	0.839065	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000277
BRD-K72951360-001-01-4	ACH-000496	NCIH1792_LUNG	HTS002	1	0.034463	9.20614	0.495707	0.586098	0.156092	0.157307	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000496

BRD-K72951360-001-01-4

ACH-000217

JHH6_LIVER

HTS002

1

0.046976

1.515511

0.609016

0.683949

0.402298

0.429359

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000217

BRD-K72951360-001-01-4

ACH-000463

NCIH460_LUNG

HTS002

1

0.063381

2.159825

0.867688

0.582818

0.132696

0.14129

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000463

BRD-K72951360-001-01-4

ACH-000748

SJSA1_BONE

HTS002

1

0.000167

4.361378

0.323281

0.880728

3.146973

3.147214

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000748

BRD-K72951360-001-01-4

ACH-000788

A2058_SKIN

HTS002

1

0.040456

6.092138

0.846533

0.582057

0.145998

0.148034

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000788

BRD-K72951360-001-01-4

ACH-000545

VMCUB1_URINARY_TRACT

HTS002

1

0.021276

1.237632

0.426773

0.723015

0.659401

0.68298

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000545

BRD-K72951360-001-01-4

ACH-000762

YD38_UPPER_AERODIGESTIVE_TRACT

HTS002

1

-0.000074

3.286509

0.478259

0.643022

0.312998

0.312984

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000762

BRD-K72951360-001-01-4

ACH-000792

BFTC909_KIDNEY

HTS002

1

0.006875

13.320607

0.23389

0.773596

1.09454

1.095679

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000792

BRD-K72951360-001-01-4

ACH-000211

DAOY_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.001896

3.996788

0.709558

0.554757

0.131823

0.131948

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000211

BRD-K72951360-001-01-4

ACH-000936

EFO27_OVARY

HTS002

1

0.057973

6.702278

0.640031

0.709054

0.49931

0.508576

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000936

BRD-K72951360-001-01-4

ACH-000882

IGR1_SKIN

HTS002

1

0.005765

1.521846

0.75393

0.712854

0.612151

0.616833

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000882

BRD-K72951360-001-01-4

ACH-000471

LI7_LIVER

HTS002

1

0.006717

7.387095

0.683157

0.697492

0.520573

0.521527

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000471

BRD-K72951360-001-01-4

ACH-000670

SBC5_LUNG

HTS002

1

0.062729

5.166902

0.905936

0.590438

0.144016

0.147801

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000670

BRD-K72951360-001-01-4

ACH-000048

TOV112D_OVARY

HTS002

1

0.019313

9.194728

0.522011

0.682656

0.43275

0.434608

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000048

BRD-K72951360-001-01-4

ACH-000259

KELLY_AUTONOMIC_GANGLIA

HTS002

1

0.043494

6.00054

0.802583

0.703845

0.49559

0.503164

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000259

BRD-K72951360-001-01-4

ACH-000599

PATU8902_PANCREAS

HTS002

1

0.029488

1.258897

0.727813

0.600395

0.184809

0.193952

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000599

BRD-K72951360-001-01-4

ACH-000716

TT2609C02_THYROID

HTS002

1

0.019181

5.51549

0.598346

0.683554

0.436798

0.439907

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000716

BRD-K72951360-001-01-4

ACH-000347

QGP1_PANCREAS

HTS002

1

0.052597

22.545351

0.467523

0.819964

1.581718

1.589535

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000347

BRD-K72951360-001-01-4

ACH-000566

SW1710_URINARY_TRACT

HTS002

1

0.042073

7.887352

0.827988

0.579034

0.140588

0.142163

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000566

BRD-K72951360-001-01-4

ACH-001016

BECKER_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.034006

1.224501

0.780187

0.635937

0.260316

0.275729

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-001016

BRD-K72951360-001-01-4

ACH-000395

NCIH520_LUNG

HTS002

1

0.05375

1.583592

0.400198

0.741399

0.711831

0.764833

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000395

BRD-K72951360-001-01-4

ACH-000407

SNU685_ENDOMETRIUM

HTS002

1

0.033057

4.573379

0.481857

0.684232

0.420457

0.426792

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000407

BRD-K72951360-001-01-4

ACH-000418

SW1353_BONE

HTS002

1

-0.10787

0.776276

0.222779

0.713228

0.720029

0.559832

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000418

BRD-K72951360-001-01-4

ACH-000008

A101D_SKIN

HTS002

1

0.000366

1.48637

0.793557

0.638068

0.298989

0.299136

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000008

BRD-K72951360-001-01-4

ACH-000191

BHT101_THYROID

HTS002

1

0.009315

1.304799

0.587475

0.595821

0.191567

0.194348

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000191

BRD-K72951360-001-01-4

ACH-000941

HEC1B_ENDOMETRIUM

HTS002

1

0.000308

0.883245

0.660832

0.800637

1.808005

1.809265

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000941

BRD-K72951360-001-01-4

ACH-000532

SNU61_LARGE_INTESTINE

HTS002

1

0.012715

2.708738

0.724585

0.643088

0.299542

0.302405

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000532

BRD-K72951360-001-01-4

ACH-000316

SNU886_LIVER

HTS002

1

0.020556

3.696865

0.7325

0.576343

0.150333

0.15205

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000316

BRD-K72951360-001-01-4

ACH-000677

SW1573_LUNG

HTS002

1

0.000501

1.098112

0.78499

0.582986

0.176

0.176161

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000677

BRD-K72951360-001-01-4

ACH-000375

G402_SOFT_TISSUE

HTS002

1

0.004666

1.350819

0.788718

0.46939

0.056609

0.057003

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000375

BRD-K72951360-001-01-4

ACH-000619

PECAPJ15_UPPER_AERODIGESTIVE_TRACT

HTS002

1

0.037887

11.485273

0.674235

0.585777

0.1533

0.154355

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000619

BRD-K72951360-001-01-4

ACH-000965

RL952_ENDOMETRIUM

HTS002

1

0.035268

1.75361

0.661475

0.553218

0.111763

0.116524

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000965

BRD-K72951360-001-01-4

ACH-000210

CADOES1_BONE

HTS002

1

0.017655

16.630178

0.282553

0.909139

4.075603

4.084422

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000210

BRD-K72951360-001-01-4

ACH-000803

COLO668_LUNG

HTS002

1

0.023947

5.866264

0.210648

0.677961

0.406903

0.410321

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000803

BRD-K72951360-001-01-4

ACH-000007

LS513_LARGE_INTESTINE

HTS002

1

-0.004452

1.155511

0.358937

0.650495

0.34223

0.339614

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000007

BRD-K72951360-001-01-4

ACH-000719

RMGI_OVARY

HTS002

1

0.001776

9.562309

0.686022

0.706593

0.577109

0.577324

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000719

BRD-K72951360-001-01-4

ACH-000484

VMRCRCW_KIDNEY

HTS002

1

0.091023

2.552803

0.553857

0.72554

0.534045

0.577782

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000484

BRD-K72951360-001-01-4

ACH-000433

CAKI1_KIDNEY

HTS002

1

0.028789

3.093996

0.429068

0.701234

0.505314

0.515092

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000433

BRD-K72951360-001-01-4

ACH-000688

OV7_OVARY

HTS002

1

0.038974

12.410009

0.360113

0.850597

2.21216

2.226674

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000688

BRD-K72951360-001-01-4

ACH-000603

BEN_LUNG

HTS002

1

-0.082965

0.963549

0.669076

0.79692

1.648093

1.405358

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000603

BRD-K72951360-001-01-4

ACH-000351

MKN1_STOMACH

HTS002

1

0.007566

1.777806

0.879945

0.486217

0.065791

0.066357

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000351

BRD-K72951360-001-01-4

ACH-000627

LCLC103H_LUNG

HTS002

1

0.00928

1.904093

0.791833

0.614145

0.228444

0.230703

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000627

BRD-K72951360-001-01-4

ACH-000916

NCIH1573_LUNG

HTS002

1

0.052672

1.175617

0.483278

0.642108

0.258534

0.28421

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000916

BRD-K72951360-001-01-4

ACH-000863

DBTRG05MG_CENTRAL_NERVOUS_SYSTEM

HTS002

1

-0.000167

6.459754

0.675051

0.691449

0.500764

0.500738

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000863

BRD-K72951360-001-01-4

ACH-000732

PECAPJ41CLONED2_UPPER_AERODIGESTIVE_TRACT

HTS002

1

0.011182

20.848701

0.814834

0.572969

0.151341

0.151506

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000732

BRD-K72951360-001-01-4

ACH-000066

HCC4006_LUNG

HTS002

1

0.000095

1.189399

0.66148

0.7237

0.709116

0.709229

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000066

BRD-K72951360-001-01-4

ACH-000015

NCIH1581_LUNG

HTS002

1

0.011946

2.224976

0.449567

0.689667

0.474826

0.480015

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000015

BRD-K72951360-001-01-4

null

HTS002

1

0.009449

1.642012

0.681388

0.628583

0.26328

0.266357

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

false

ACH-000511_FAILED_STR

BRD-K72951360-001-01-4

ACH-000674

NUGC4_STOMACH

HTS002

1

0.013768

1.860164

0.844056

0.540942

0.109235

0.110887

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000674

BRD-K72951360-001-01-4

ACH-000892

NCIH1563_LUNG

HTS002

1

-0.004558

0.93533

0.871107

0.626698

0.276134

0.273467

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000892

BRD-K72951360-001-01-4

ACH-000909

JHUEM2_ENDOMETRIUM

HTS002

1

0.005907

1.501474

0.972946

0.442714

0.043352

0.043696

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000909

BRD-K72951360-001-01-4

ACH-000237

JHOM1_OVARY

HTS002

1

0.018726

7.714124

0.721911

0.684936

0.443452

0.445652

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000237

BRD-K72951360-001-01-4

ACH-000811

SKOV3_OVARY

HTS002

1

0.021002

3.034191

0.589658

0.671535

0.385493

0.390984

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000811

BRD-K72951360-001-01-4

ACH-000312

SKNBE2_AUTONOMIC_GANGLIA

HTS002

1

0.004768

1.586118

0.604392

0.652158

0.337502

0.339547

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000312

BRD-K72951360-001-01-4

ACH-000390

LUDLU1_LUNG

HTS002

1

0.026034

1.202638

0.472243

0.718685

0.624113

0.652489

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000390

BRD-K72951360-001-01-4

ACH-000901

HCC1359_LUNG

HTS002

1

0.005588

1.682321

0.435003

0.631625

0.275036

0.27688

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000901

BRD-K72951360-001-01-4

ACH-000307

PK1_PANCREAS

HTS002

1

0.004604

1.526795

0.579138

0.632202

0.277935

0.279624

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000307

BRD-K72951360-001-01-4

ACH-000289

SNU466_CENTRAL_NERVOUS_SYSTEM

HTS002

1

-0.133374

0.698056

0.601143

0.700586

0.661419

0.471376

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000289

BRD-K72951360-001-01-4

ACH-000309

SKLU1_LUNG

HTS002

1

0.017286

6.920964

0.485297

0.687968

0.459019

0.461359

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000309

BRD-K72951360-001-01-4

ACH-000733

NCIH1838_LUNG

HTS002

1

0.018115

4.835398

0.527797

0.577536

0.153711

0.154889

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000733

BRD-K72951360-001-01-4

ACH-000268

SNU245_BILIARY_TRACT

HTS002

1

0.171243

6.593828

0.339494

0.76428

0.632858

0.674407

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000268

BRD-K72951360-001-01-4

ACH-000758

MKN74_STOMACH

HTS002

1

0.058141

3.320474

0.300013

0.855213

2.254566

2.340084

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000758

BRD-K72951360-001-01-4

ACH-000693

KYSE180_OESOPHAGUS

HTS002

1

0.047727

4.170814

0.856808

0.697675

0.459214

0.470393

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000693

BRD-K72951360-001-01-4

ACH-000684

KMRC1_KIDNEY

HTS002

1

0.072167

1.512641

0.333475

0.608492

0.166805

0.18491

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000684

BRD-K72951360-001-01-4

ACH-000264

CALU6_LUNG

HTS002

1

0.129862

11.062357

0.809234

0.624458

0.151739

0.155921

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000264

BRD-K72951360-001-01-4

ACH-000027

GOS3_CENTRAL_NERVOUS_SYSTEM

HTS002

1

-0.053066

1.118628

0.634793

0.748471

0.924717

0.844982

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000027

BRD-K72951360-001-01-4

ACH-000671

HUH6_LIVER

HTS002

1

0.042645

7.365177

0.632018

0.598262

0.170406

0.172481

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000671

BRD-K72951360-001-01-4

ACH-000205

PK59_PANCREAS

HTS002

1

0.028413

1.712142

0.716764

0.573884

0.14184

0.14677

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000205

BRD-K72951360-001-01-4

ACH-000720

TCCSUP_URINARY_TRACT

HTS002

1

0.055462

8.98435

0.509636

0.712664

0.522322

0.529202

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000720

BRD-K72951360-001-01-4

ACH-000814

HS939T_SKIN

HTS002

1

0.00014

11.083271

0.5998

0.700357

0.545757

0.545771

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000814

BRD-K72951360-001-01-4

ACH-000885

TOV21G_OVARY

HTS002

1

0.008438

1.404687

0.807313

0.429879

0.03767

0.038129

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000885

BRD-K72951360-001-01-4

ACH-000663

OVTOKO_OVARY

HTS002

1

0.111766

4.811852

0.469645

0.736085

0.559492

0.589696

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000663

BRD-K72951360-001-01-4

ACH-000647

TE1_OESOPHAGUS

HTS002

1

0.002597

1.789963

0.618302

0.644014

0.31355

0.314463

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000647

BRD-K72951360-001-01-4

ACH-000243

DANG_PANCREAS

HTS002

1

0.013551

2.157034

0.55308

0.602428

0.200211

0.202778

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000243

BRD-K72951360-001-01-4

ACH-000255

LMSU_STOMACH

HTS002

1

0.000345

1.500957

0.618506

0.567833

0.150832

0.150901

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000255

BRD-K72951360-001-01-4

ACH-000335

MSTO211H_PLEURA

HTS002

1

-0.0001

1.11445

0.706476

0.516481

0.091806

0.09179

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000335

BRD-K72951360-001-01-4

ACH-000147

T47D_BREAST

HTS002

1

0.026436

1.412009

0.579044

0.567006

0.133712

0.138956

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000147

BRD-K72951360-001-01-4

ACH-000090

PC3_PROSTATE

HTS002

1

0.127461

2.783892

0.759419

0.634286

0.171228

0.190318

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000090

BRD-K72951360-001-01-4

ACH-000171

VMRCRCZ_KIDNEY

HTS002

1

0.033955

5.433957

0.502877

0.699

0.486262

0.492596

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000171

BRD-K72951360-001-01-4

ACH-000614

RVH421_SKIN

HTS002

1

0.002889

1.306429

0.685826

0.612496

0.231439

0.232468

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000614

BRD-K72951360-001-01-4

ACH-000132

JHOS2_OVARY

HTS002

1

0.139144

7.716213

0.534213

0.648729

0.190682

0.198914

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000132

BRD-K72951360-001-01-4

ACH-000274

HS852T_SKIN

HTS002

1

-0.031499

2.660107

0.676001

0.888525

3.464595

3.385933

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000274

BRD-K72951360-001-01-4

null

HTS002

1

0.000837

1.525819

0.768861

0.658275

0.363418

0.363817

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

false

ACH-000807_FAILED_STR

BRD-K72951360-001-01-4

ACH-000810

SKMEL30_SKIN

HTS002

1

0.004688

1.650798

0.563861

0.713819

0.617829

0.621365

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000810

BRD-K72951360-001-01-4

ACH-000343

NCIH522_LUNG

HTS002

1

0.095803

7.68532

0.410104

0.724083

0.51756

0.532084

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000343

BRD-K72951360-001-01-4

ACH-000022

PATU8988S_PANCREAS

HTS002

1

0.436604

13.146116

0.274374

0.865521

0.986377

1.154168

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000022

BRD-K72951360-001-01-4

ACH-000192

MFE280_ENDOMETRIUM

HTS002

1

0.005181

1.685207

0.647637

0.49759

0.074403

0.074864

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000192

BRD-K72951360-001-01-4

null

HTS002

1

0.205677

1.912581

0.607508

0.694702

0.240084

0.316735

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

false

ACH-000409_FAILED_STR

BRD-K72951360-001-01-4

ACH-000959

SNUC4_LARGE_INTESTINE

HTS002

1

0.105223

2.210771

0.824859

0.658465

0.24627

0.27405

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000959

BRD-K72951360-001-01-4

null

HTS002

1

0.012142

2.049047

0.801491

0.65539

0.33886

0.34295

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

false

ACH-000028_FAILED_STR

BRD-K72951360-001-01-4

ACH-000637

KYSE520_OESOPHAGUS

HTS002

1

-0.02858

0.907459

0.766682

0.645325

0.335088

0.315178

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000637

BRD-K72951360-001-01-4

ACH-000968

COLO792_SKIN

HTS002

1

0.006345

14.866391

0.488708

0.790379

1.290995

1.292105

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000968

BRD-K72951360-001-01-4

ACH-000155

SW1990_PANCREAS

HTS002

1

0.066093

1.674886

0.784983

0.630623

0.215538

0.234578

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000155

BRD-K72951360-001-01-4

ACH-000133

HS729_SOFT_TISSUE

HTS002

1

0.008802

3.884325

0.367492

0.664597

0.3749

0.376619

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000133

BRD-K72951360-001-01-4

ACH-000605

TE6_OESOPHAGUS

HTS002

1

0.074362

1.98571

0.684519

0.598914

0.149247

0.161853

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000605

BRD-K72951360-001-01-4

ACH-000775

NCIH727_LUNG

HTS002

1

0.120583

1.584194

0.082699

0.883383

3.015649

3.58952

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000775

BRD-K72951360-001-01-4

ACH-000042

PANC0203_PANCREAS

HTS002

1

0.054245

4.195355

0.793598

0.688656

0.40983

0.421203

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000042

BRD-K72951360-001-01-4

ACH-000860

NCIH358_LUNG

HTS002

1

0.005277

1.350081

0.642883

0.618255

0.242462

0.244375

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000860

BRD-K72951360-001-01-4

ACH-000994

HEC59_ENDOMETRIUM

HTS002

1

-0.003214

1.429226

0.849271

0.657423

0.362108

0.360488

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000994

BRD-K72951360-001-01-4

ACH-000277

HCC1419_BREAST

HTS002

1

-0.121042

0.848794

0.520795

0.754034

1.083226

0.839065

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000277

BRD-K72951360-001-01-4

ACH-000496

NCIH1792_LUNG

HTS002

1

0.034463

9.20614

0.495707

0.586098

0.156092

0.157307

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000496