donb-hf/secondary-screen-dose-response-curve-parameters

broad_id string	depmap_id string	ccle_name string	screen_id string	upper_limit int64	lower_limit float64	slope float64	r2 float64	auc float64	ec50 float64	ic50 float64	name string	moa string	target string	disease.area string	indication string	smiles string	phase string	passed_str_profiling bool	row_name string
BRD-K72951360-001-01-4	ACH-000866	NCIH1048_LUNG	HTS002	1	0.012586	1.575502	0.660863	0.496474	0.070931	0.072088	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000866
BRD-K72951360-001-01-4	ACH-000869	NCIH1568_LUNG	HTS002	1	0.000088	6.917454	0.73349	0.700258	0.545314	0.545328	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000869
BRD-K72951360-001-01-4	ACH-000117	EFM192A_BREAST	HTS002	1	0.17359	5.748041	0.253021	0.741615	0.481193	0.518251	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000117
BRD-K72951360-001-01-4	ACH-000678	MKN7_STOMACH	HTS002	1	-0.001279	1.437053	0.637709	0.690851	0.502547	0.501654	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000678
BRD-K72951360-001-01-4	ACH-000493	SNU423_LIVER	HTS002	1	-0.000315	1.5325	0.638384	0.626255	0.266653	0.266544	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000493
BRD-K72951360-001-01-4	ACH-000468	PK45H_PANCREAS	HTS002	1	-0.063638	0.897808	0.463623	0.743547	0.940229	0.822775	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000468
BRD-K72951360-001-01-4	ACH-000097	ZR751_BREAST	HTS002	1	0.00309	1.048367	0.618402	0.534684	0.108307	0.108949	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000097
BRD-K72951360-001-01-4	ACH-000313	KMRC3_KIDNEY	HTS002	1	0.049848	2.20318	0.802495	0.675353	0.363205	0.380938	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000313
BRD-K72951360-001-01-4	ACH-000169	RD_SOFT_TISSUE	HTS002	1	0.098227	1.47499	0.729775	0.685592	0.340879	0.395366	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000169
BRD-K72951360-001-01-4	null	null	HTS002	1	0.003095	2.402506	0.860239	0.594323	0.192758	0.193256	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	false	ACH-000010_FAILED_STR
BRD-K72951360-001-01-4	ACH-000895	CL34_LARGE_INTESTINE	HTS002	1	0.023342	5.943745	0.611949	0.577522	0.150294	0.151508	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000895
BRD-K72951360-001-01-4	ACH-000841	NCIH2087_LUNG	HTS002	1	0.00132	1.455203	0.51624	0.577367	0.164877	0.165176	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000841
BRD-K72951360-001-01-4	ACH-000414	NCIH1944_LUNG	HTS002	1	0.001289	1.415101	0.820013	0.622177	0.255437	0.255904	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000414
BRD-K72951360-001-01-4	ACH-000026	253JBV_URINARY_TRACT	HTS002	1	0.029958	1.103519	0.761694	0.615951	0.217055	0.229555	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000026
BRD-K72951360-001-01-4	ACH-000649	786O_KIDNEY	HTS002	1	0.105241	6.069394	0.718285	0.730096	0.535451	0.556712	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000649
BRD-K72951360-001-01-4	ACH-000966	IGROV1_OVARY	HTS002	1	0.000284	2.042328	0.703615	0.646314	0.322986	0.323076	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000966
BRD-K72951360-001-01-4	ACH-000950	LOVO_LARGE_INTESTINE	HTS002	1	0.023786	6.937498	0.644807	0.593665	0.176119	0.177361	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000950
BRD-K72951360-001-01-4	ACH-000750	LOXIMVI_SKIN	HTS002	1	0.139448	2.433238	0.573183	0.565766	0.074714	0.08546	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000750
BRD-K72951360-001-01-4	ACH-000958	SW48_LARGE_INTESTINE	HTS002	1	0.062757	2.688342	0.255591	0.553644	0.09838	0.103413	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000958
BRD-K72951360-001-01-4	ACH-000270	HPAC_PANCREAS	HTS002	1	0.000268	0.838506	0.36825	0.606324	0.228116	0.228261	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000270
BRD-K72951360-001-01-4	ACH-000535	BXPC3_PANCREAS	HTS002	1	0.022057	7.70626	-0.196732	0.921461	4.588562	4.615505	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000535
BRD-K72951360-001-01-4	ACH-000480	HUH7_LIVER	HTS002	1	0.045454	6.626808	-0.108783	0.855039	2.290792	2.323976	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000480
BRD-K72951360-001-01-4	ACH-000281	KP2_PANCREAS	HTS002	1	0.015167	12.221501	0.377523	0.844176	2.153661	2.159096	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000281
BRD-K72951360-001-01-4	ACH-000897	FTC238_THYROID	HTS002	1	0.057057	7.004305	0.561121	0.611303	0.183122	0.186317	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000897
BRD-K72951360-001-01-4	ACH-000389	H4_CENTRAL_NERVOUS_SYSTEM	HTS002	1	-0.046704	0.893581	0.313058	0.680657	0.483391	0.437419	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000389
BRD-K72951360-001-01-4	ACH-000862	KMBC2_URINARY_TRACT	HTS002	1	0.012746	1.731669	0.875135	0.491654	0.067597	0.068612	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000862
BRD-K72951360-001-01-4	ACH-000776	ONS76_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.011298	2.052599	0.868299	0.614341	0.227082	0.229624	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000776
BRD-K72951360-001-01-4	ACH-000023	PATU8988T_PANCREAS	HTS002	1	0.003331	5.223401	0.84075	0.57176	0.154591	0.154789	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000023
BRD-K72951360-001-01-4	ACH-000011	253J_URINARY_TRACT	HTS002	1	0.003559	1.257058	0.835309	0.606922	0.218821	0.220069	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000011
BRD-K72951360-001-01-4	ACH-000973	639V_URINARY_TRACT	HTS002	1	0.028236	3.899022	0.878944	0.57645	0.145584	0.14777	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000973
BRD-K72951360-001-01-4	ACH-001024	CHL1_SKIN	HTS002	1	0.004675	1.331976	0.821184	0.564357	0.143318	0.144333	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-001024
BRD-K72951360-001-01-4	ACH-000971	HCT116_LARGE_INTESTINE	HTS002	1	0.020786	2.260743	0.861624	0.670978	0.383746	0.391022	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000971
BRD-K72951360-001-01-4	ACH-000486	KU1919_URINARY_TRACT	HTS002	1	0.000523	2.053789	0.738397	0.619992	0.249891	0.250019	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000486
BRD-K72951360-001-01-4	ACH-000997	HCT15_LARGE_INTESTINE	HTS002	1	0.005253	2.336118	0.653283	0.611876	0.226813	0.227841	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000997
BRD-K72951360-001-01-4	ACH-000552	HT29_LARGE_INTESTINE	HTS002	1	-0.000381	4.49184	0.633707	0.690585	0.496582	0.496498	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000552
BRD-K72951360-001-01-4	ACH-000796	MCAS_OVARY	HTS002	1	0.000066	1.547822	0.853647	0.599261	0.204951	0.204968	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000796
BRD-K72951360-001-01-4	ACH-000652	SUIT2_PANCREAS	HTS002	1	0.245757	4.944119	0.717787	0.764451	0.482878	0.553664	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000652
BRD-K72951360-001-01-4	ACH-000452	TE8_OESOPHAGUS	HTS002	1	-0.066613	1.189862	0.588945	0.796456	1.509084	1.358514	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000452
BRD-K72951360-001-01-4	ACH-000458	CJM_SKIN	HTS002	1	0.000672	1.233613	0.607246	0.621637	0.255825	0.256104	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000458
BRD-K72951360-001-01-4	ACH-000221	SNU398_LIVER	HTS002	1	0.016498	1.568459	0.65078	0.665079	0.368442	0.376409	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000221
BRD-K72951360-001-01-4	ACH-000970	SNUC5_LARGE_INTESTINE	HTS002	1	0.10588	1.786057	0.462718	0.809923	1.289006	1.472703	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000970
BRD-K72951360-001-01-4	ACH-000893	NCIH1651_LUNG	HTS002	1	0.004849	1.216903	0.727522	0.528109	0.100499	0.101307	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000893
BRD-K72951360-001-01-4	ACH-000562	HCC78_LUNG	HTS002	1	0.05047	1.008001	0.68622	0.579175	0.136777	0.152006	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000562
BRD-K72951360-001-01-4	ACH-000769	LK2_LUNG	HTS002	1	0.032544	5.360955	0.677488	0.574843	0.140583	0.142359	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000769
BRD-K72951360-001-01-4	ACH-000384	SW780_URINARY_TRACT	HTS002	1	0.311164	18.430857	0.143069	0.73315	0.233004	0.245645	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000384
BRD-K72951360-001-01-4	ACH-000505	RKN_SOFT_TISSUE	HTS002	1	0.035282	6.901615	0.739398	0.696483	0.472137	0.47717	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000505
BRD-K72951360-001-01-4	ACH-000765	WM983B_SKIN	HTS002	1	-0.31495	0.952737	0.522605	0.845973	2.993794	1.792817	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000765
BRD-K72951360-001-01-4	ACH-000858	KNS62_LUNG	HTS002	1	-0.060077	0.919286	0.114705	0.758974	1.101973	0.974018	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000858
BRD-K72951360-001-01-4	ACH-000595	LN229_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.058068	11.005617	0.373184	0.79701	1.235305	1.24924	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000595
BRD-K72951360-001-01-4	ACH-000052	A673_BONE	HTS002	1	0.056084	4.44972	0.64542	0.658594	0.299006	0.307108	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000052
BRD-K72951360-001-01-4	ACH-000979	DU145_PROSTATE	HTS002	1	0.027424	1.7478	0.868669	0.62889	0.246751	0.254845	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000979
BRD-K72951360-001-01-4	ACH-000571	T98G_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.040358	3.432977	0.823721	0.690194	0.435953	0.446773	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000571
BRD-K72951360-001-01-4	ACH-000812	COLO783_SKIN	HTS002	1	0.008999	2.26571	0.726636	0.593261	0.186331	0.187831	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000812
BRD-K72951360-001-01-4	ACH-000891	HCC1438_LUNG	HTS002	1	0.007732	4.446377	0.754857	0.636077	0.284657	0.285656	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000891
BRD-K72951360-001-01-4	ACH-000667	HCC44_LUNG	HTS002	1	0.00948	1.559619	0.810352	0.628123	0.262228	0.265466	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000667
BRD-K72951360-001-01-4	ACH-000734	JHH5_LIVER	HTS002	1	0.079024	1.860656	0.647467	0.636708	0.217642	0.238725	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000734
BRD-K72951360-001-01-4	ACH-000416	NCIH838_LUNG	HTS002	1	0.016675	2.383031	0.951658	0.603909	0.200637	0.203513	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000416
BRD-K72951360-001-01-4	ACH-000802	BFTC905_URINARY_TRACT	HTS002	1	0.095344	9.590313	0.484453	0.606853	0.147396	0.150684	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000802
BRD-K72951360-001-01-4	ACH-000946	HEC265_ENDOMETRIUM	HTS002	1	0.000968	0.910622	0.432316	0.527226	0.101948	0.102165	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000946
BRD-K72951360-001-01-4	ACH-000472	HSC2_UPPER_AERODIGESTIVE_TRACT	HTS002	1	-0.005859	0.890108	0.691011	0.653553	0.365851	0.361094	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000472
BRD-K72951360-001-01-4	ACH-000962	OC314_OVARY	HTS002	1	0.00692	3.2134	0.789073	0.508736	0.082258	0.082615	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000962
BRD-K72951360-001-01-4	ACH-000383	OE33_OESOPHAGUS	HTS002	1	0.108886	7.107833	0.508933	0.739454	0.585833	0.60643	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000383
BRD-K72951360-001-01-4	ACH-000824	KYSE510_OESOPHAGUS	HTS002	1	0.011423	2.962497	0.873388	0.579777	0.161636	0.162902	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000824
BRD-K72951360-001-01-4	ACH-001307	8505C_THYROID	HTS002	1	0.008697	8.175378	0.484101	0.714943	0.613913	0.615232	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-001307
BRD-K72951360-001-01-4	ACH-000756	GI1_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.043207	2.702965	0.459304	0.594201	0.163141	0.168688	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000756
BRD-K72951360-001-01-4	ACH-000681	A549_LUNG	HTS002	1	-0.027082	0.961063	0.742273	0.666716	0.412241	0.390225	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000681
BRD-K72951360-001-01-4	ACH-000444	LU99_LUNG	HTS002	1	0.002019	2.018606	0.699721	0.562179	0.141624	0.141909	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000444
BRD-K72951360-001-01-4	ACH-000142	CAL29_URINARY_TRACT	HTS002	1	-0.00005	2.227115	0.7469	0.59155	0.189953	0.189944	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000142
BRD-K72951360-001-01-4	ACH-000905	5637_URINARY_TRACT	HTS002	1	0.043296	10.634993	0.443	0.704877	0.501113	0.505399	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000905
BRD-K72951360-001-01-4	ACH-000680	SW948_LARGE_INTESTINE	HTS002	1	0.098195	6.882527	0.430789	0.622731	0.172544	0.178113	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000680
BRD-K72951360-001-01-4	ACH-000921	NCIH1339_LUNG	HTS002	1	0.016425	7.173511	0.799425	0.697531	0.505799	0.50816	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000921
BRD-K72951360-001-01-4	ACH-000954	HEC1A_ENDOMETRIUM	HTS002	1	0.017195	5.988771	0.591035	0.545572	0.112548	0.113208	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000954
BRD-K72951360-001-01-4	ACH-000280	SNU840_OVARY	HTS002	1	0.004879	1.517941	0.871795	0.619004	0.244024	0.245606	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000280
BRD-K72951360-001-01-4	ACH-000012	HCC827_LUNG	HTS002	1	0.003574	1.521351	0.797208	0.590318	0.185286	0.186162	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000012
BRD-K72951360-001-01-4	ACH-000098	GAMG_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.118115	14.597885	0.549562	0.734242	0.536996	0.547001	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000098
BRD-K72951360-001-01-4	ACH-000589	NCIH1437_LUNG	HTS002	1	0.011591	1.705455	0.781098	0.613252	0.224567	0.227677	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000589
BRD-K72951360-001-01-4	ACH-000738	GB1_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.075661	1.999641	0.525931	0.70831	0.468322	0.50837	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000738
BRD-K72951360-001-01-4	ACH-000837	NCIH322_LUNG	HTS002	1	0.00236	0.827647	0.827828	0.588926	0.189804	0.190892	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000837
BRD-K72951360-001-01-4	ACH-000967	SNUC2A_LARGE_INTESTINE	HTS002	1	0.234866	4.116644	0.445394	0.663677	0.140444	0.163842	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000967
BRD-K72951360-001-01-4	ACH-000662	CORL23_LUNG	HTS002	1	0.014846	3.198583	0.712358	0.692084	0.481685	0.486246	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000662
BRD-K72951360-001-01-4	ACH-000427	NCIN87_STOMACH	HTS002	1	-0.050119	0.620613	0.329549	0.527259	0.104622	0.089697	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000427
BRD-K72951360-001-01-4	ACH-000774	RERFLCAD2_LUNG	HTS002	1	-0.061032	0.662279	0.298003	0.711127	0.771122	0.648037	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000774
BRD-K72951360-001-01-4	ACH-000624	HCC1806_BREAST	HTS002	1	0.001541	1.287014	0.669652	0.747124	0.88548	0.887607	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000624
BRD-K72951360-001-01-4	ACH-000888	NCIH1793_LUNG	HTS002	1	-0.056301	1.141839	0.754125	0.792782	1.468877	1.337834	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000888
BRD-K72951360-001-01-4	ACH-000449	MESSA_SOFT_TISSUE	HTS002	1	0.004774	4.629254	0.646597	0.536349	0.108794	0.109019	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000449
BRD-K72951360-001-01-4	ACH-000587	NCIH1975_LUNG	HTS002	1	0.016819	2.272103	0.800025	0.59133	0.177111	0.179798	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000587
BRD-K72951360-001-01-4	ACH-000404	K029AX_SKIN	HTS002	1	0.036351	1.660427	0.443565	0.734762	0.696824	0.729231	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000404
BRD-K72951360-001-01-4	ACH-000813	T3M10_LUNG	HTS002	1	0.022934	1.127552	0.585465	0.498956	0.068923	0.071854	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000813
BRD-K72951360-001-01-4	ACH-000311	NCIH2122_LUNG	HTS002	1	0.062493	3.070024	0.470615	0.596682	0.153796	0.160632	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000311
BRD-K72951360-001-01-4	ACH-000849	MDAMB468_BREAST	HTS002	1	0.009843	1.587067	0.476618	0.610664	0.220536	0.223316	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000849
BRD-K72951360-001-01-4	ACH-000868	HCC1195_LUNG	HTS002	1	0.001154	1.047705	0.69297	0.456817	0.050789	0.050901	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000868
BRD-K72951360-001-01-4	ACH-000978	EN_ENDOMETRIUM	HTS002	1	0.009991	6.899722	0.32426	0.876539	2.981573	2.990308	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000978
BRD-K72951360-001-01-4	ACH-000408	TE5_OESOPHAGUS	HTS002	1	-0.045504	1.023785	0.51291	0.761464	1.08674	0.998106	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000408
BRD-K72951360-001-01-4	ACH-000344	SNU668_STOMACH	HTS002	1	0.000029	1.091174	0.696627	0.667675	0.408348	0.40837	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000344
BRD-K72951360-001-01-4	ACH-000161	CORL105_LUNG	HTS002	1	0.157636	1.034961	0.194822	0.65763	0.196404	0.283188	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000161
BRD-K72951360-001-01-4	ACH-000835	GCT_SOFT_TISSUE	HTS002	1	-0.024135	0.960593	0.627689	0.710188	0.644775	0.613896	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000835
BRD-K72951360-001-01-4	ACH-000819	LN18_CENTRAL_NERVOUS_SYSTEM	HTS002	1	0.001271	5.197266	0.688736	0.682089	0.455493	0.455716	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000819
BRD-K72951360-001-01-4	ACH-000062	RERFLCMS_LUNG	HTS002	1	0.013943	2.330923	0.957368	0.500496	0.0733	0.074195	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000062
BRD-K72951360-001-01-4	ACH-000473	RT112_URINARY_TRACT	HTS002	1	0.000273	5.493981	0.789437	0.543383	0.118876	0.118888	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000473
BRD-K72951360-001-01-4	ACH-000176	LOUNH91_LUNG	HTS002	1	0.073886	4.666979	0.785342	0.707422	0.466206	0.482456	valrubicin	DNA inhibitor, topoisomerase inhibitor	TOP2A	oncology	bladder cancer	CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1	Launched	true	ACH-000176

BRD-K72951360-001-01-4

ACH-000866

NCIH1048_LUNG

HTS002

1

0.012586

1.575502

0.660863

0.496474

0.070931

0.072088

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000866

BRD-K72951360-001-01-4

ACH-000869

NCIH1568_LUNG

HTS002

1

0.000088

6.917454

0.73349

0.700258

0.545314

0.545328

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000869

BRD-K72951360-001-01-4

ACH-000117

EFM192A_BREAST

HTS002

1

0.17359

5.748041

0.253021

0.741615

0.481193

0.518251

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000117

BRD-K72951360-001-01-4

ACH-000678

MKN7_STOMACH

HTS002

1

-0.001279

1.437053

0.637709

0.690851

0.502547

0.501654

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000678

BRD-K72951360-001-01-4

ACH-000493

SNU423_LIVER

HTS002

1

-0.000315

1.5325

0.638384

0.626255

0.266653

0.266544

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000493

BRD-K72951360-001-01-4

ACH-000468

PK45H_PANCREAS

HTS002

1

-0.063638

0.897808

0.463623

0.743547

0.940229

0.822775

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000468

BRD-K72951360-001-01-4

ACH-000097

ZR751_BREAST

HTS002

1

0.00309

1.048367

0.618402

0.534684

0.108307

0.108949

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000097

BRD-K72951360-001-01-4

ACH-000313

KMRC3_KIDNEY

HTS002

1

0.049848

2.20318

0.802495

0.675353

0.363205

0.380938

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000313

BRD-K72951360-001-01-4

ACH-000169

RD_SOFT_TISSUE

HTS002

1

0.098227

1.47499

0.729775

0.685592

0.340879

0.395366

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000169

BRD-K72951360-001-01-4

null

HTS002

1

0.003095

2.402506

0.860239

0.594323

0.192758

0.193256

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

false

ACH-000010_FAILED_STR

BRD-K72951360-001-01-4

ACH-000895

CL34_LARGE_INTESTINE

HTS002

1

0.023342

5.943745

0.611949

0.577522

0.150294

0.151508

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000895

BRD-K72951360-001-01-4

ACH-000841

NCIH2087_LUNG

HTS002

1

0.00132

1.455203

0.51624

0.577367

0.164877

0.165176

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000841

BRD-K72951360-001-01-4

ACH-000414

NCIH1944_LUNG

HTS002

1

0.001289

1.415101

0.820013

0.622177

0.255437

0.255904

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000414

BRD-K72951360-001-01-4

ACH-000026

253JBV_URINARY_TRACT

HTS002

1

0.029958

1.103519

0.761694

0.615951

0.217055

0.229555

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000026

BRD-K72951360-001-01-4

ACH-000649

786O_KIDNEY

HTS002

1

0.105241

6.069394

0.718285

0.730096

0.535451

0.556712

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000649

BRD-K72951360-001-01-4

ACH-000966

IGROV1_OVARY

HTS002

1

0.000284

2.042328

0.703615

0.646314

0.322986

0.323076

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000966

BRD-K72951360-001-01-4

ACH-000950

LOVO_LARGE_INTESTINE

HTS002

1

0.023786

6.937498

0.644807

0.593665

0.176119

0.177361

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000950

BRD-K72951360-001-01-4

ACH-000750

LOXIMVI_SKIN

HTS002

1

0.139448

2.433238

0.573183

0.565766

0.074714

0.08546

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000750

BRD-K72951360-001-01-4

ACH-000958

SW48_LARGE_INTESTINE

HTS002

1

0.062757

2.688342

0.255591

0.553644

0.09838

0.103413

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000958

BRD-K72951360-001-01-4

ACH-000270

HPAC_PANCREAS

HTS002

1

0.000268

0.838506

0.36825

0.606324

0.228116

0.228261

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000270

BRD-K72951360-001-01-4

ACH-000535

BXPC3_PANCREAS

HTS002

1

0.022057

7.70626

-0.196732

0.921461

4.588562

4.615505

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000535

BRD-K72951360-001-01-4

ACH-000480

HUH7_LIVER

HTS002

1

0.045454

6.626808

-0.108783

0.855039

2.290792

2.323976

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000480

BRD-K72951360-001-01-4

ACH-000281

KP2_PANCREAS

HTS002

1

0.015167

12.221501

0.377523

0.844176

2.153661

2.159096

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000281

BRD-K72951360-001-01-4

ACH-000897

FTC238_THYROID

HTS002

1

0.057057

7.004305

0.561121

0.611303

0.183122

0.186317

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000897

BRD-K72951360-001-01-4

ACH-000389

H4_CENTRAL_NERVOUS_SYSTEM

HTS002

1

-0.046704

0.893581

0.313058

0.680657

0.483391

0.437419

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000389

BRD-K72951360-001-01-4

ACH-000862

KMBC2_URINARY_TRACT

HTS002

1

0.012746

1.731669

0.875135

0.491654

0.067597

0.068612

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000862

BRD-K72951360-001-01-4

ACH-000776

ONS76_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.011298

2.052599

0.868299

0.614341

0.227082

0.229624

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000776

BRD-K72951360-001-01-4

ACH-000023

PATU8988T_PANCREAS

HTS002

1

0.003331

5.223401

0.84075

0.57176

0.154591

0.154789

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000023

BRD-K72951360-001-01-4

ACH-000011

253J_URINARY_TRACT

HTS002

1

0.003559

1.257058

0.835309

0.606922

0.218821

0.220069

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000011

BRD-K72951360-001-01-4

ACH-000973

639V_URINARY_TRACT

HTS002

1

0.028236

3.899022

0.878944

0.57645

0.145584

0.14777

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000973

BRD-K72951360-001-01-4

ACH-001024

CHL1_SKIN

HTS002

1

0.004675

1.331976

0.821184

0.564357

0.143318

0.144333

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-001024

BRD-K72951360-001-01-4

ACH-000971

HCT116_LARGE_INTESTINE

HTS002

1

0.020786

2.260743

0.861624

0.670978

0.383746

0.391022

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000971

BRD-K72951360-001-01-4

ACH-000486

KU1919_URINARY_TRACT

HTS002

1

0.000523

2.053789

0.738397

0.619992

0.249891

0.250019

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000486

BRD-K72951360-001-01-4

ACH-000997

HCT15_LARGE_INTESTINE

HTS002

1

0.005253

2.336118

0.653283

0.611876

0.226813

0.227841

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000997

BRD-K72951360-001-01-4

ACH-000552

HT29_LARGE_INTESTINE

HTS002

1

-0.000381

4.49184

0.633707

0.690585

0.496582

0.496498

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000552

BRD-K72951360-001-01-4

ACH-000796

MCAS_OVARY

HTS002

1

0.000066

1.547822

0.853647

0.599261

0.204951

0.204968

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000796

BRD-K72951360-001-01-4

ACH-000652

SUIT2_PANCREAS

HTS002

1

0.245757

4.944119

0.717787

0.764451

0.482878

0.553664

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000652

BRD-K72951360-001-01-4

ACH-000452

TE8_OESOPHAGUS

HTS002

1

-0.066613

1.189862

0.588945

0.796456

1.509084

1.358514

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000452

BRD-K72951360-001-01-4

ACH-000458

CJM_SKIN

HTS002

1

0.000672

1.233613

0.607246

0.621637

0.255825

0.256104

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000458

BRD-K72951360-001-01-4

ACH-000221

SNU398_LIVER

HTS002

1

0.016498

1.568459

0.65078

0.665079

0.368442

0.376409

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000221

BRD-K72951360-001-01-4

ACH-000970

SNUC5_LARGE_INTESTINE

HTS002

1

0.10588

1.786057

0.462718

0.809923

1.289006

1.472703

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000970

BRD-K72951360-001-01-4

ACH-000893

NCIH1651_LUNG

HTS002

1

0.004849

1.216903

0.727522

0.528109

0.100499

0.101307

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000893

BRD-K72951360-001-01-4

ACH-000562

HCC78_LUNG

HTS002

1

0.05047

1.008001

0.68622

0.579175

0.136777

0.152006

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000562

BRD-K72951360-001-01-4

ACH-000769

LK2_LUNG

HTS002

1

0.032544

5.360955

0.677488

0.574843

0.140583

0.142359

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000769

BRD-K72951360-001-01-4

ACH-000384

SW780_URINARY_TRACT

HTS002

1

0.311164

18.430857

0.143069

0.73315

0.233004

0.245645

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000384

BRD-K72951360-001-01-4

ACH-000505

RKN_SOFT_TISSUE

HTS002

1

0.035282

6.901615

0.739398

0.696483

0.472137

0.47717

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000505

BRD-K72951360-001-01-4

ACH-000765

WM983B_SKIN

HTS002

1

-0.31495

0.952737

0.522605

0.845973

2.993794

1.792817

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000765

BRD-K72951360-001-01-4

ACH-000858

KNS62_LUNG

HTS002

1

-0.060077

0.919286

0.114705

0.758974

1.101973

0.974018

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000858

BRD-K72951360-001-01-4

ACH-000595

LN229_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.058068

11.005617

0.373184

0.79701

1.235305

1.24924

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000595

BRD-K72951360-001-01-4

ACH-000052

A673_BONE

HTS002

1

0.056084

4.44972

0.64542

0.658594

0.299006

0.307108

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000052

BRD-K72951360-001-01-4

ACH-000979

DU145_PROSTATE

HTS002

1

0.027424

1.7478

0.868669

0.62889

0.246751

0.254845

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000979

BRD-K72951360-001-01-4

ACH-000571

T98G_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.040358

3.432977

0.823721

0.690194

0.435953

0.446773

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000571

BRD-K72951360-001-01-4

ACH-000812

COLO783_SKIN

HTS002

1

0.008999

2.26571

0.726636

0.593261

0.186331

0.187831

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000812

BRD-K72951360-001-01-4

ACH-000891

HCC1438_LUNG

HTS002

1

0.007732

4.446377

0.754857

0.636077

0.284657

0.285656

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000891

BRD-K72951360-001-01-4

ACH-000667

HCC44_LUNG

HTS002

1

0.00948

1.559619

0.810352

0.628123

0.262228

0.265466

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000667

BRD-K72951360-001-01-4

ACH-000734

JHH5_LIVER

HTS002

1

0.079024

1.860656

0.647467

0.636708

0.217642

0.238725

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000734

BRD-K72951360-001-01-4

ACH-000416

NCIH838_LUNG

HTS002

1

0.016675

2.383031

0.951658

0.603909

0.200637

0.203513

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000416

BRD-K72951360-001-01-4

ACH-000802

BFTC905_URINARY_TRACT

HTS002

1

0.095344

9.590313

0.484453

0.606853

0.147396

0.150684

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000802

BRD-K72951360-001-01-4

ACH-000946

HEC265_ENDOMETRIUM

HTS002

1

0.000968

0.910622

0.432316

0.527226

0.101948

0.102165

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000946

BRD-K72951360-001-01-4

ACH-000472

HSC2_UPPER_AERODIGESTIVE_TRACT

HTS002

1

-0.005859

0.890108

0.691011

0.653553

0.365851

0.361094

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000472

BRD-K72951360-001-01-4

ACH-000962

OC314_OVARY

HTS002

1

0.00692

3.2134

0.789073

0.508736

0.082258

0.082615

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000962

BRD-K72951360-001-01-4

ACH-000383

OE33_OESOPHAGUS

HTS002

1

0.108886

7.107833

0.508933

0.739454

0.585833

0.60643

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000383

BRD-K72951360-001-01-4

ACH-000824

KYSE510_OESOPHAGUS

HTS002

1

0.011423

2.962497

0.873388

0.579777

0.161636

0.162902

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000824

BRD-K72951360-001-01-4

ACH-001307

8505C_THYROID

HTS002

1

0.008697

8.175378

0.484101

0.714943

0.613913

0.615232

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-001307

BRD-K72951360-001-01-4

ACH-000756

GI1_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.043207

2.702965

0.459304

0.594201

0.163141

0.168688

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000756

BRD-K72951360-001-01-4

ACH-000681

A549_LUNG

HTS002

1

-0.027082

0.961063

0.742273

0.666716

0.412241

0.390225

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000681

BRD-K72951360-001-01-4

ACH-000444

LU99_LUNG

HTS002

1

0.002019

2.018606

0.699721

0.562179

0.141624

0.141909

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000444

BRD-K72951360-001-01-4

ACH-000142

CAL29_URINARY_TRACT

HTS002

1

-0.00005

2.227115

0.7469

0.59155

0.189953

0.189944

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000142

BRD-K72951360-001-01-4

ACH-000905

5637_URINARY_TRACT

HTS002

1

0.043296

10.634993

0.443

0.704877

0.501113

0.505399

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000905

BRD-K72951360-001-01-4

ACH-000680

SW948_LARGE_INTESTINE

HTS002

1

0.098195

6.882527

0.430789

0.622731

0.172544

0.178113

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000680

BRD-K72951360-001-01-4

ACH-000921

NCIH1339_LUNG

HTS002

1

0.016425

7.173511

0.799425

0.697531

0.505799

0.50816

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000921

BRD-K72951360-001-01-4

ACH-000954

HEC1A_ENDOMETRIUM

HTS002

1

0.017195

5.988771

0.591035

0.545572

0.112548

0.113208

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000954

BRD-K72951360-001-01-4

ACH-000280

SNU840_OVARY

HTS002

1

0.004879

1.517941

0.871795

0.619004

0.244024

0.245606

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000280

BRD-K72951360-001-01-4

ACH-000012

HCC827_LUNG

HTS002

1

0.003574

1.521351

0.797208

0.590318

0.185286

0.186162

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000012

BRD-K72951360-001-01-4

ACH-000098

GAMG_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.118115

14.597885

0.549562

0.734242

0.536996

0.547001

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000098

BRD-K72951360-001-01-4

ACH-000589

NCIH1437_LUNG

HTS002

1

0.011591

1.705455

0.781098

0.613252

0.224567

0.227677

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000589

BRD-K72951360-001-01-4

ACH-000738

GB1_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.075661

1.999641

0.525931

0.70831

0.468322

0.50837

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000738

BRD-K72951360-001-01-4

ACH-000837

NCIH322_LUNG

HTS002

1

0.00236

0.827647

0.827828

0.588926

0.189804

0.190892

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000837

BRD-K72951360-001-01-4

ACH-000967

SNUC2A_LARGE_INTESTINE

HTS002

1

0.234866

4.116644

0.445394

0.663677

0.140444

0.163842

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000967

BRD-K72951360-001-01-4

ACH-000662

CORL23_LUNG

HTS002

1

0.014846

3.198583

0.712358

0.692084

0.481685

0.486246

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000662

BRD-K72951360-001-01-4

ACH-000427

NCIN87_STOMACH

HTS002

1

-0.050119

0.620613

0.329549

0.527259

0.104622

0.089697

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000427

BRD-K72951360-001-01-4

ACH-000774

RERFLCAD2_LUNG

HTS002

1

-0.061032

0.662279

0.298003

0.711127

0.771122

0.648037

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000774

BRD-K72951360-001-01-4

ACH-000624

HCC1806_BREAST

HTS002

1

0.001541

1.287014

0.669652

0.747124

0.88548

0.887607

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000624

BRD-K72951360-001-01-4

ACH-000888

NCIH1793_LUNG

HTS002

1

-0.056301

1.141839

0.754125

0.792782

1.468877

1.337834

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000888

BRD-K72951360-001-01-4

ACH-000449

MESSA_SOFT_TISSUE

HTS002

1

0.004774

4.629254

0.646597

0.536349

0.108794

0.109019

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000449

BRD-K72951360-001-01-4

ACH-000587

NCIH1975_LUNG

HTS002

1

0.016819

2.272103

0.800025

0.59133

0.177111

0.179798

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000587

BRD-K72951360-001-01-4

ACH-000404

K029AX_SKIN

HTS002

1

0.036351

1.660427

0.443565

0.734762

0.696824

0.729231

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000404

BRD-K72951360-001-01-4

ACH-000813

T3M10_LUNG

HTS002

1

0.022934

1.127552

0.585465

0.498956

0.068923

0.071854

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000813

BRD-K72951360-001-01-4

ACH-000311

NCIH2122_LUNG

HTS002

1

0.062493

3.070024

0.470615

0.596682

0.153796

0.160632

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000311

BRD-K72951360-001-01-4

ACH-000849

MDAMB468_BREAST

HTS002

1

0.009843

1.587067

0.476618

0.610664

0.220536

0.223316

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000849

BRD-K72951360-001-01-4

ACH-000868

HCC1195_LUNG

HTS002

1

0.001154

1.047705

0.69297

0.456817

0.050789

0.050901

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000868

BRD-K72951360-001-01-4

ACH-000978

EN_ENDOMETRIUM

HTS002

1

0.009991

6.899722

0.32426

0.876539

2.981573

2.990308

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000978

BRD-K72951360-001-01-4

ACH-000408

TE5_OESOPHAGUS

HTS002

1

-0.045504

1.023785

0.51291

0.761464

1.08674

0.998106

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000408

BRD-K72951360-001-01-4

ACH-000344

SNU668_STOMACH

HTS002

1

0.000029

1.091174

0.696627

0.667675

0.408348

0.40837

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000344

BRD-K72951360-001-01-4

ACH-000161

CORL105_LUNG

HTS002

1

0.157636

1.034961

0.194822

0.65763

0.196404

0.283188

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000161

BRD-K72951360-001-01-4

ACH-000835

GCT_SOFT_TISSUE

HTS002

1

-0.024135

0.960593

0.627689

0.710188

0.644775

0.613896

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000835

BRD-K72951360-001-01-4

ACH-000819

LN18_CENTRAL_NERVOUS_SYSTEM

HTS002

1

0.001271

5.197266

0.688736

0.682089

0.455493

0.455716

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000819

BRD-K72951360-001-01-4

ACH-000062

RERFLCMS_LUNG

HTS002

1

0.013943

2.330923

0.957368

0.500496

0.0733

0.074195

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000062

BRD-K72951360-001-01-4

ACH-000473

RT112_URINARY_TRACT

HTS002

1

0.000273

5.493981

0.789437

0.543383

0.118876

0.118888

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000473

BRD-K72951360-001-01-4

ACH-000176

LOUNH91_LUNG

HTS002

1

0.073886

4.666979

0.785342

0.707422

0.466206

0.482456

valrubicin

DNA inhibitor, topoisomerase inhibitor

TOP2A

oncology

bladder cancer

CCCCC(=O)OCC(=O)[C@@]1(O)C[C@H](O[C@H]2C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O2)c2c(O)c3C(=O)c4c(OC)cccc4C(=O)c3c(O)c2C1

Launched

true

ACH-000176