broad_id
string | depmap_id
string | ccle_name
string | screen_id
string | upper_limit
int64 | lower_limit
float64 | slope
float64 | r2
float64 | auc
float64 | ec50
float64 | ic50
float64 | name
string | moa
string | target
string | disease.area
string | indication
string | smiles
string | phase
string | passed_str_profiling
bool | row_name
string |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
BRD-K47832606-001-30-1
|
ACH-000592
|
TM31_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 0.204918 | 5.749631 | 0.723898 | 0.422942 | 0.008734 | 0.009573 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000592
|
BRD-K47832606-001-30-1
|
ACH-000368
|
SNU1105_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 0.04548 | 1.07715 | 0.76943 | 0.486676 | 0.053925 | 0.058917 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000368
|
BRD-K47832606-001-30-1
|
ACH-000517
|
SNU410_PANCREAS
|
HTS002
| 1 | 0.600649 | 3.307255 | 0.093178 | 0.837586 | 0.193202 | null |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000517
|
BRD-K47832606-001-30-1
|
ACH-000374
|
HCC1143_BREAST
|
HTS002
| 1 | 0.378181 | 3.909151 | 0.519839 | 0.716126 | 0.119129 | 0.170961 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000374
|
BRD-K47832606-001-30-1
|
ACH-000527
|
OVISE_OVARY
|
HTS002
| 1 | 1.574697 | -6.347603 | 0.263887 | 1.226856 | 0.028131 | null |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000527
|
BRD-K47832606-001-30-1
|
ACH-000091
|
OV56_OVARY
|
HTS002
| 1 | 0.110026 | 2.3579 | 0.724945 | 0.565415 | 0.087507 | 0.097234 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000091
|
BRD-K47832606-001-30-1
|
ACH-000759
|
MDAMB175VII_BREAST
|
HTS002
| 1 | 0.555084 | 10.387974 | 0.411952 | 0.773339 | 0.071281 | null |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000759
|
BRD-K47832606-001-30-1
|
ACH-000417
|
PANC0813_PANCREAS
|
HTS002
| 1 | 0.35402 | 4.40984 | 0.654029 | 0.694943 | 0.102278 | 0.135216 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000417
|
BRD-K47832606-001-30-1
|
ACH-000308
|
EFO21_OVARY
|
HTS002
| 1 | 0.275524 | 3.138964 | 0.747395 | 0.680093 | 0.137733 | 0.177762 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000308
|
BRD-K47832606-001-30-1
|
ACH-000991
|
SNU81_LARGE_INTESTINE
|
HTS002
| 1 | 0.155078 | 2.158383 | 0.628351 | 0.408154 | 0.011156 | 0.01325 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000991
|
BRD-K47832606-001-30-1
|
ACH-000948
|
2313287_STOMACH
|
HTS002
| 1 | 0.031302 | 7.267951 | 0.781909 | 0.436181 | 0.035241 | 0.035555 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000948
|
BRD-K47832606-001-30-1
|
ACH-000481
|
NCIH2170_LUNG
|
HTS002
| 1 | 0.133713 | 1.418205 | 0.804231 | 0.451814 | 0.021439 | 0.026699 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000481
|
BRD-K47832606-001-30-1
|
ACH-000771
|
BICR56_UPPER_AERODIGESTIVE_TRACT
|
HTS002
| 1 | 0.332189 | 2.776513 | 0.810202 | 0.530063 | 0.010821 | 0.016034 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000771
|
BRD-K47832606-001-30-1
|
ACH-000159
|
OSRC2_KIDNEY
|
HTS002
| 1 | 0.364305 | 0.865641 | 0.289425 | 0.643701 | 0.042633 | 0.19234 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000159
|
BRD-K47832606-001-30-1
|
ACH-000929
|
NCIH2110_LUNG
|
HTS002
| 1 | 0.106618 | 13.461645 | 0.784582 | 0.487677 | 0.038298 | 0.038986 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000929
|
BRD-K47832606-001-30-1
|
ACH-000118
|
HUPT3_PANCREAS
|
HTS002
| 1 | 0.196185 | 6.01448 | 0.742599 | 0.617108 | 0.098284 | 0.106772 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000118
|
BRD-K47832606-001-30-1
|
ACH-000482
|
RERFLCKJ_LUNG
|
HTS002
| 1 | 0.209081 | 0.961911 | 0.59392 | 0.554978 | 0.042013 | 0.073772 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000482
|
BRD-K47832606-001-30-1
|
ACH-000352
|
HCC1428_BREAST
|
HTS002
| 1 | 0.496686 | 4.68284 | 0.421858 | 0.77325 | 0.126282 | 0.36861 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000352
|
BRD-K47832606-001-30-1
|
ACH-000235
|
PANC0403_PANCREAS
|
HTS002
| 1 | 0.276355 | 0.991082 | 0.95224 | 0.637089 | 0.076973 | 0.173338 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000235
|
BRD-K47832606-001-30-1
|
ACH-000900
|
NCIH23_LUNG
|
HTS002
| 1 | 0.142428 | 1.881793 | 0.664751 | 0.569782 | 0.076868 | 0.09186 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000900
|
BRD-K47832606-001-30-1
|
ACH-000479
|
KNS81_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 0.302238 | 4.645642 | 0.559675 | 0.690271 | 0.134668 | 0.164428 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000479
|
BRD-K47832606-001-30-1
|
ACH-000911
|
NUGC3_STOMACH
|
HTS002
| 1 | 0.156934 | 6.042306 | 0.6101 | 0.599198 | 0.099179 | 0.105559 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000911
|
BRD-K47832606-001-30-1
|
ACH-000401
|
COLO800_SKIN
|
HTS002
| 1 | 0.247439 | 3.015661 | 0.710173 | 0.639461 | 0.095707 | 0.120032 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000401
|
BRD-K47832606-001-30-1
|
ACH-000276
|
HCC38_BREAST
|
HTS002
| 1 | 0.197809 | 4.403089 | 0.641381 | 0.424539 | 0.009478 | 0.010627 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000276
|
BRD-K47832606-001-30-1
|
ACH-000724
|
HT1376_URINARY_TRACT
|
HTS002
| 1 | 1.581356 | -6.764285 | 0.400425 | 1.245461 | 0.036728 | null |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000724
|
BRD-K47832606-001-30-1
|
ACH-000092
|
NCIH2452_PLEURA
|
HTS002
| 1 | 0.179648 | 2.219766 | 0.775186 | 0.561693 | 0.056009 | 0.068448 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000092
|
BRD-K47832606-001-30-1
|
ACH-000890
|
SW1271_LUNG
|
HTS002
| 1 | 0.28275 | 2.508518 | 0.751874 | 0.611714 | 0.0523 | 0.072914 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000890
|
BRD-K47832606-001-30-1
| null | null |
HTS002
| 1 | 0.151462 | 0.927242 | 0.841699 | 0.605564 | 0.110751 | 0.163442 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| false |
ACH-000539_FAILED_STR
|
BRD-K47832606-001-30-1
|
ACH-000800
|
NCIH446_LUNG
|
HTS002
| 1 | 0.212611 | 1.112965 | 0.654439 | 0.606946 | 0.078749 | 0.129519 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000800
|
BRD-K47832606-001-30-1
|
ACH-000899
|
WM88_SKIN
|
HTS002
| 1 | 0.406512 | 2.793613 | 0.264737 | 0.800271 | 0.381695 | 0.695644 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000899
|
BRD-K47832606-001-30-1
|
ACH-000996
|
HEC251_ENDOMETRIUM
|
HTS002
| 1 | 0.320904 | 7.023096 | 0.440961 | 0.708833 | 0.155969 | 0.180521 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000996
|
BRD-K47832606-001-30-1
|
ACH-000622
|
KNS42_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 0.494707 | 1.450434 | 0.395338 | 0.833919 | 0.414677 | 9.540067 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000622
|
BRD-K47832606-001-30-1
|
ACH-000403
|
NCIH747_LARGE_INTESTINE
|
HTS002
| 1 | 1.657332 | -1.016041 | 0.271147 | 1.322117 | 0.070825 | null |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000403
|
BRD-K47832606-001-30-1
|
ACH-000141
|
SNU308_BILIARY_TRACT
|
HTS002
| 1 | 0.216497 | 3.151552 | 0.499031 | 0.673959 | 0.176295 | 0.211071 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000141
|
BRD-K47832606-001-30-1
|
ACH-000988
|
MFE319_ENDOMETRIUM
|
HTS002
| 1 | 0.120683 | 1.442114 | 0.746785 | 0.540134 | 0.062482 | 0.075673 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000988
|
BRD-K47832606-001-30-1
|
ACH-000848
|
JHH7_LIVER
|
HTS002
| 1 | 0.00883 | 0.467807 | 0.605265 | 0.392306 | 0.019924 | 0.020698 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000848
|
BRD-K47832606-001-30-1
|
ACH-000785
|
NCIH2126_LUNG
|
HTS002
| 1 | 0.212212 | 15.501565 | 0.68156 | 0.620645 | 0.093447 | 0.096837 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000785
|
BRD-K47832606-001-30-1
|
ACH-000544
|
OE21_OESOPHAGUS
|
HTS002
| 1 | 0.246681 | 2.047196 | 0.639905 | 0.627373 | 0.082291 | 0.114709 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000544
|
BRD-K47832606-001-30-1
|
ACH-000982
|
GP2D_LARGE_INTESTINE
|
HTS002
| 1 | 0.074166 | 2.839041 | 0.6487 | 0.311493 | 0.007341 | 0.007768 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000982
|
BRD-K47832606-001-30-1
|
ACH-000021
|
NCIH1693_LUNG
|
HTS002
| 1 | 0.252604 | 5.954565 | 0.713687 | 0.640453 | 0.093881 | 0.105657 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000021
|
BRD-K47832606-001-30-1
|
ACH-000823
|
KYSE140_OESOPHAGUS
|
HTS002
| 1 | 0.564972 | 8.366932 | 0.525436 | 0.784242 | 0.081245 | null |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000823
|
BRD-K47832606-001-30-1
|
ACH-000915
|
IPC298_SKIN
|
HTS002
| 1 | 0.148635 | 2.444932 | 0.817013 | 0.547743 | 0.057708 | 0.066666 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000915
|
BRD-K47832606-001-30-1
|
ACH-000984
|
HEC6_ENDOMETRIUM
|
HTS002
| 1 | 0.411003 | 5.377584 | 0.486013 | 0.734041 | 0.125024 | 0.172341 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000984
|
BRD-K47832606-001-30-1
|
ACH-000579
|
UACC257_SKIN
|
HTS002
| 1 | 0.196997 | 4.327446 | 0.621179 | 0.627008 | 0.11026 | 0.123789 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000579
|
BRD-K47832606-001-30-1
|
ACH-001306
|
8305C_THYROID
|
HTS002
| 1 | 0.233736 | 3.401729 | 0.669215 | 0.612001 | 0.073455 | 0.088403 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-001306
|
BRD-K47832606-001-30-1
|
ACH-000318
|
TE10_OESOPHAGUS
|
HTS002
| 1 | 0.510956 | 3.451241 | 0.453499 | 0.772035 | 0.108511 | null |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000318
|
BRD-K47832606-001-30-1
|
ACH-000840
|
HCC366_LUNG
|
HTS002
| 1 | 0.197047 | 4.538247 | 0.776965 | 0.638962 | 0.12736 | 0.142227 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000840
|
BRD-K47832606-001-30-1
|
ACH-000503
|
BICR16_UPPER_AERODIGESTIVE_TRACT
|
HTS002
| 1 | 0.239478 | 0.960805 | 0.086885 | 0.570963 | 0.041402 | 0.0816 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000503
|
BRD-K47832606-001-30-1
|
ACH-000726
|
TE14_OESOPHAGUS
|
HTS002
| 1 | 0.0597 | 11.72214 | 0.718487 | 0.462359 | 0.038931 | 0.039355 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000726
|
BRD-K47832606-001-30-1
|
ACH-000919
|
IM95_STOMACH
|
HTS002
| 1 | 0.155158 | 3.437801 | 0.806267 | 0.501274 | 0.032519 | 0.036231 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000919
|
BRD-K47832606-001-30-1
|
ACH-000188
|
SCC25_UPPER_AERODIGESTIVE_TRACT
|
HTS002
| 1 | 0.239745 | 1.335901 | 0.657056 | 0.640996 | 0.102388 | 0.166924 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000188
|
BRD-K47832606-001-30-1
|
ACH-000618
|
SNU1041_UPPER_AERODIGESTIVE_TRACT
|
HTS002
| 1 | 0.314298 | 1.203351 | 0.808546 | 0.642545 | 0.063459 | 0.14453 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000618
|
BRD-K47832606-001-30-1
|
ACH-000822
|
SKMEL24_SKIN
|
HTS002
| 1 | 0.252512 | 4.548161 | 0.694863 | 0.56596 | 0.035713 | 0.041685 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000822
|
BRD-K47832606-001-30-1
|
ACH-000292
|
NCIH841_LUNG
|
HTS002
| 1 | 0.280117 | 1.466905 | 0.714638 | 0.649086 | 0.088251 | 0.154503 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000292
|
BRD-K47832606-001-30-1
|
ACH-000827
|
WM793_SKIN
|
HTS002
| 1 | 0.230942 | 3.108553 | 0.714148 | 0.594581 | 0.060022 | 0.073263 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000827
|
BRD-K47832606-001-30-1
|
ACH-000411
|
769P_KIDNEY
|
HTS002
| 1 | 0.235906 | 1.754204 | 0.748517 | 0.618787 | 0.078957 | 0.11361 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000411
|
BRD-K47832606-001-30-1
|
ACH-000139
|
PANC0327_PANCREAS
|
HTS002
| 1 | 0.082286 | 4.95867 | 0.402811 | 0.469965 | 0.036805 | 0.038165 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000139
|
BRD-K47832606-001-30-1
|
ACH-000569
|
ISTMES1_PLEURA
|
HTS002
| 1 | 0.195015 | 3.859518 | 0.626384 | 0.535731 | 0.037099 | 0.042168 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000569
|
BRD-K47832606-001-30-1
|
ACH-000741
|
UBLC1_URINARY_TRACT
|
HTS002
| 1 | 0.224551 | 1.083615 | 0.748752 | 0.567493 | 0.044329 | 0.076849 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000741
|
BRD-K47832606-001-30-1
|
ACH-000278
|
COV362_OVARY
|
HTS002
| 1 | 0.250786 | 4.007816 | 0.850159 | 0.661543 | 0.124777 | 0.148452 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000278
|
BRD-K47832606-001-30-1
|
ACH-000425
|
UACC62_SKIN
|
HTS002
| 1 | 0.133571 | 2.716541 | 0.835834 | 0.519147 | 0.045821 | 0.051375 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000425
|
BRD-K47832606-001-30-1
|
ACH-000013
|
ONCODG1_OVARY
|
HTS002
| 1 | 0.079654 | 1.747293 | 0.816235 | 0.399542 | 0.017771 | 0.019627 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000013
|
BRD-K47832606-001-30-1
|
ACH-000231
|
KALS1_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 0.134096 | 4.395951 | 0.703685 | 0.602401 | 0.116106 | 0.124653 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000231
|
BRD-K47832606-001-30-1
|
ACH-000730
|
SKMEL5_SKIN
|
HTS002
| 1 | 0.133707 | 6.427289 | 0.668434 | 0.543506 | 0.060146 | 0.063129 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000730
|
BRD-K47832606-001-30-1
|
ACH-000500
|
SNU46_UPPER_AERODIGESTIVE_TRACT
|
HTS002
| 1 | 0.186123 | 5.86869 | 0.638694 | 0.626209 | 0.115992 | 0.12557 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000500
|
BRD-K47832606-001-30-1
|
ACH-000222
|
ASPC1_PANCREAS
|
HTS002
| 1 | 0.348398 | 3.049314 | 0.774362 | 0.621901 | 0.035853 | 0.053026 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000222
|
BRD-K47832606-001-30-1
|
ACH-000477
|
MALME3M_SKIN
|
HTS002
| 1 | 0.563401 | 3.449363 | 0.354648 | 0.750789 | 0.039301 | null |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000477
|
BRD-K47832606-001-30-1
|
ACH-000223
|
HCC1937_BREAST
|
HTS002
| 1 | 0.666326 | 9.033428 | 0.088142 | 0.926881 | 1.192547 | null |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000223
|
BRD-K47832606-001-30-1
|
ACH-000495
|
TUHR4TKB_KIDNEY
|
HTS002
| 1 | 0.30924 | 4.012946 | 0.584115 | 0.680665 | 0.11264 | 0.143211 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000495
|
BRD-K47832606-001-30-1
|
ACH-000434
|
NCIH1915_LUNG
|
HTS002
| 1 | 0.31085 | 1.512025 | 0.67046 | 0.776415 | 0.431661 | 0.821008 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000434
|
BRD-K47832606-001-30-1
|
ACH-000744
|
NCIH1623_LUNG
|
HTS002
| 1 | 0.177229 | 2.009605 | 0.860734 | 0.384637 | 0.007021 | 0.008729 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000744
|
BRD-K47832606-001-30-1
|
ACH-000107
|
CAPAN2_PANCREAS
|
HTS002
| 1 | 0.545662 | 2.485072 | 0.112966 | 0.804139 | 0.152475 | null |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000107
|
BRD-K47832606-001-30-1
|
ACH-000516
|
CAL78_BONE
|
HTS002
| 1 | 0.097075 | 1.838411 | 0.712268 | 0.473611 | 0.034909 | 0.039258 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000516
|
BRD-K47832606-001-30-1
|
ACH-000182
|
SNU869_BILIARY_TRACT
|
HTS002
| 1 | 0.265129 | 4.666619 | 0.718244 | 0.577596 | 0.037805 | 0.044449 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000182
|
BRD-K47832606-001-30-1
|
ACH-000898
|
SNU719_STOMACH
|
HTS002
| 1 | 0.47826 | 2.007647 | 0.710815 | 0.682808 | 0.027399 | 0.130616 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000898
|
BRD-K47832606-001-30-1
|
ACH-000040
|
U118MG_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 0.137908 | 1.560254 | 0.578689 | 0.659567 | 0.216986 | 0.266844 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000040
|
BRD-K47832606-001-30-1
|
ACH-000808
|
HUH28_BILIARY_TRACT
|
HTS002
| 1 | 0.273508 | 1.462329 | 0.452368 | 0.767595 | 0.451824 | 0.776523 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000808
|
BRD-K47832606-001-30-1
|
ACH-000447
|
NCIH2228_LUNG
|
HTS002
| 1 | 0.141632 | 2.675443 | 0.885198 | 0.581294 | 0.087949 | 0.099608 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000447
|
BRD-K47832606-001-30-1
|
ACH-000715
|
SNU1214_UPPER_AERODIGESTIVE_TRACT
|
HTS002
| 1 | 0.307571 | 1.267058 | 0.484476 | 0.658294 | 0.083242 | 0.176862 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000715
|
BRD-K47832606-001-30-1
|
ACH-000186
|
NCIH2444_LUNG
|
HTS002
| 1 | 0.121192 | 1.422415 | 0.500482 | 0.518594 | 0.049082 | 0.059659 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000186
|
BRD-K47832606-001-30-1
|
ACH-000542
|
HEYA8_OVARY
|
HTS002
| 1 | 0.423218 | 4.779226 | 0.345201 | 0.64039 | 0.023572 | 0.034887 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000542
|
BRD-K47832606-001-30-1
|
ACH-000943
|
RKO_LARGE_INTESTINE
|
HTS002
| 1 | 0.090835 | 1.67177 | 0.592832 | 0.432664 | 0.023418 | 0.026401 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000943
|
BRD-K47832606-001-30-1
|
ACH-000174
|
CAL62_THYROID
|
HTS002
| 1 | 0.291317 | 1.401878 | 0.61475 | 0.604845 | 0.044614 | 0.083209 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000174
|
BRD-K47832606-001-30-1
|
ACH-000393
|
HLF_LIVER
|
HTS002
| 1 | 0.149017 | 5.530415 | 0.373698 | 0.634911 | 0.15557 | 0.16585 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000393
|
BRD-K47832606-001-30-1
|
ACH-000018
|
T24_URINARY_TRACT
|
HTS002
| 1 | 0.279445 | 8.222911 | 0.718671 | 0.684679 | 0.14313 | 0.15811 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000018
|
BRD-K47832606-001-30-1
|
ACH-000906
|
ES2_OVARY
|
HTS002
| 1 | 0.134151 | 1.685652 | 0.821614 | 0.494021 | 0.03443 | 0.04144 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000906
|
BRD-K47832606-001-30-1
|
ACH-000784
|
KYSE70_OESOPHAGUS
|
HTS002
| 1 | 0.699416 | 0.3392 | 0.116018 | 0.845376 | 0.063532 | null |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000784
|
BRD-K47832606-001-30-1
|
ACH-000265
|
KP4_PANCREAS
|
HTS002
| 1 | 0.182245 | 1.911268 | 0.788031 | 0.601898 | 0.088782 | 0.112548 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000265
|
BRD-K47832606-001-30-1
|
ACH-000880
|
AGS_STOMACH
|
HTS002
| 1 | 0.324143 | 3.690438 | 0.87331 | 0.587894 | 0.02693 | 0.035744 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000880
|
BRD-K47832606-001-30-1
|
ACH-000961
|
ISHIKAWAHERAKLIO02ER_ENDOMETRIUM
|
HTS002
| 1 | 0.3914 | 4.192349 | 0.822527 | 0.629954 | 0.027385 | 0.039417 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000961
|
BRD-K47832606-001-30-1
|
ACH-000847
|
HGC27_STOMACH
|
HTS002
| 1 | 0.048421 | 3.607178 | 0.613417 | 0.490412 | 0.055348 | 0.056933 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000847
|
BRD-K47832606-001-30-1
|
ACH-000896
|
647V_URINARY_TRACT
|
HTS002
| 1 | 0.12779 | 3.156777 | 0.756101 | 0.501675 | 0.039097 | 0.042929 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000896
|
BRD-K47832606-001-30-1
|
ACH-000685
|
L33_PANCREAS
|
HTS002
| 1 | 0.14621 | 2.53518 | 0.604751 | 0.466061 | 0.023141 | 0.026524 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000685
|
BRD-K47832606-001-30-1
|
ACH-000376
|
SF295_CENTRAL_NERVOUS_SYSTEM
|
HTS002
| 1 | 0.2079 | 2.718428 | 0.780866 | 0.538881 | 0.035203 | 0.042899 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000376
|
BRD-K47832606-001-30-1
|
ACH-000428
|
UO31_KIDNEY
|
HTS002
| 1 | 0.572987 | 1.171904 | 0.410863 | 0.740398 | 0.027158 | null |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000428
|
BRD-K47832606-001-30-1
|
ACH-000749
|
DMS273_LUNG
|
HTS002
| 1 | 0.16178 | 3.917149 | 0.728341 | 0.528303 | 0.0425 | 0.04696 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000749
|
BRD-K47832606-001-30-1
|
ACH-000572
|
G361_SKIN
|
HTS002
| 1 | -0.088868 | 0.743712 | 0.311312 | 0.710989 | 0.717745 | 0.576021 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000572
|
BRD-K47832606-001-30-1
|
ACH-000704
|
OAW42_OVARY
|
HTS002
| 1 | 0.18698 | 0.985248 | 0.546846 | 0.606506 | 0.091496 | 0.147179 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000704
|
BRD-K47832606-001-30-1
|
ACH-000457
|
CAL54_KIDNEY
|
HTS002
| 1 | 0.370278 | 1.131461 | 0.350642 | 0.7406 | 0.185159 | 0.610128 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000457
|
BRD-K47832606-001-30-1
|
ACH-000601
|
MIAPACA2_PANCREAS
|
HTS002
| 1 | 0.195466 | 3.054522 | 0.862145 | 0.560103 | 0.049621 | 0.058367 |
floxuridine
|
DNA synthesis inhibitor
|
TYMS
|
oncology
|
colorectal cancer
|
OC[C@H]1OC(C[C@H]1O)n1cc(F)c(=O)[nH]c1=O, OC[C@H]1O[C@H](C[C@@H]1O)n1cc(F)c(=O)[nH]c1=O
|
Launched
| true |
ACH-000601
|
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