donb-hf/secondary-screen-dose-response-curve-parameters

broad_id string	depmap_id string	ccle_name string	screen_id string	upper_limit int64	lower_limit float64	slope float64	r2 float64	auc float64	ec50 float64	ic50 float64	name string	moa string	target string	disease.area string	indication string	smiles string	phase string	passed_str_profiling bool	row_name string
BRD-A98990573-003-01-3	ACH-000480	HUH7_LIVER	HTS002	1	1.324224	-0.128318	-0.122661	1.2024	4.62325	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000480
BRD-A98990573-003-01-3	ACH-000281	KP2_PANCREAS	HTS002	1	15.510764	2.295423	-0.321783	1.000001	3,612.317274	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000281
BRD-A98990573-003-01-3	ACH-000897	FTC238_THYROID	HTS002	1	1.835751	-0.015413	0.001432	1.54188	13,887,541,600,055,404	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000897
BRD-A98990573-003-01-3	ACH-000389	H4_CENTRAL_NERVOUS_SYSTEM	HTS002	1	1.561929	-0.096359	-0.028321	1.448968	162,102.794614	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000389
BRD-A98990573-003-01-3	ACH-000862	KMBC2_URINARY_TRACT	HTS002	1	1.521251	-0.061001	0.021827	1.284177	1.557338	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000862
BRD-A98990573-003-01-3	ACH-000776	ONS76_CENTRAL_NERVOUS_SYSTEM	HTS002	1	1.423457	-0.12339	-0.024998	1.249453	1.576824	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000776
BRD-A98990573-003-01-3	ACH-000023	PATU8988T_PANCREAS	HTS002	1	1.620223	-0.264201	0.146633	1.255104	0.016815	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000023
BRD-A98990573-003-01-3	ACH-000011	253J_URINARY_TRACT	HTS002	1	1.564166	0.099456	-0.032355	1.301252	0.019361	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000011
BRD-A98990573-003-01-3	ACH-000973	639V_URINARY_TRACT	HTS002	1	1.741875	-0.081131	0.001129	1.396441	0.436023	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000973
BRD-A98990573-003-01-3	ACH-001024	CHL1_SKIN	HTS002	1	1.813534	-0.167312	0.026972	1.416792	0.106589	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-001024
BRD-A98990573-003-01-3	ACH-000971	HCT116_LARGE_INTESTINE	HTS002	1	1.288773	1.08576	-0.10527	1.248526	0.001855	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000971
BRD-A98990573-003-01-3	ACH-000486	KU1919_URINARY_TRACT	HTS002	1	1.374036	-0.222058	-0.073943	1.273026	10.176591	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000486
BRD-A98990573-003-01-3	ACH-000997	HCT15_LARGE_INTESTINE	HTS002	1	1.508362	0.085375	0.022693	1.263036	0.034134	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000997
BRD-A98990573-003-01-3	ACH-000552	HT29_LARGE_INTESTINE	HTS002	1	1.623043	-0.081142	0.000514	1.515596	23,833,677.253788	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000552
BRD-A98990573-003-01-3	ACH-000796	MCAS_OVARY	HTS002	1	1.33417	0.010324	-0.033116	1.165521	0.479242	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000796
BRD-A98990573-003-01-3	ACH-000652	SUIT2_PANCREAS	HTS002	1	1.632154	-0.039386	-0.003732	1.352823	29.930865	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000652
BRD-A98990573-003-01-3	ACH-000452	TE8_OESOPHAGUS	HTS002	1	1.484911	0.165505	-0.038621	1.287723	0.007067	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000452
BRD-A98990573-003-01-3	ACH-000458	CJM_SKIN	HTS002	1	1.74168	-0.013627	-0.002435	1.444336	499,942,726,627.35	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000458
BRD-A98990573-003-01-3	ACH-000221	SNU398_LIVER	HTS002	1	2.417817	0.066095	-0.013351	1.642478	1.37533	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000221
BRD-A98990573-003-01-3	ACH-000970	SNUC5_LARGE_INTESTINE	HTS002	1	2.017877	-0.317641	0.021475	1.531059	0.108233	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000970
BRD-A98990573-003-01-3	ACH-000893	NCIH1651_LUNG	HTS002	1	1.482333	0.164283	-0.075208	1.377909	0.000022	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000893
BRD-A98990573-003-01-3	ACH-000562	HCC78_LUNG	HTS002	1	1.872368	0.103596	0.033422	1.314313	22.310079	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000562
BRD-A98990573-003-01-3	ACH-000769	LK2_LUNG	HTS002	1	1.840631	0.139391	0.026816	1.376077	0.376606	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000769
BRD-A98990573-003-01-3	ACH-000858	KNS62_LUNG	HTS002	1	1.521935	-0.002187	-0.001344	1.302639	708,545,613,969,306,050,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000858
BRD-A98990573-003-01-3	ACH-000595	LN229_CENTRAL_NERVOUS_SYSTEM	HTS002	1	2.130337	0.288872	0.141273	1.502528	0.190659	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000595
BRD-A98990573-003-01-3	ACH-000052	A673_BONE	HTS002	1	1.983414	-0.14041	0.000037	1.374243	0.002134	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000052
BRD-A98990573-003-01-3	ACH-000979	DU145_PROSTATE	HTS002	1	1.585481	0.293565	0.052222	1.158138	3.842981	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000979
BRD-A98990573-003-01-3	ACH-000571	T98G_CENTRAL_NERVOUS_SYSTEM	HTS002	1	1.398819	0.050182	-0.02024	1.212443	0.005678	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000571
BRD-A98990573-003-01-3	ACH-000812	COLO783_SKIN	HTS002	1	1.554188	-0.113242	-0.009886	1.273885	0.063346	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000812
BRD-A98990573-003-01-3	ACH-000891	HCC1438_LUNG	HTS002	1	1.680534	0.065755	0.021049	1.391383	0.000752	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000891
BRD-A98990573-003-01-3	ACH-000802	BFTC905_URINARY_TRACT	HTS002	1	1.515346	0.27546	0.011442	1.241738	0.130686	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000802
BRD-A98990573-003-01-3	ACH-000472	HSC2_UPPER_AERODIGESTIVE_TRACT	HTS002	1	1.456211	-0.138394	0.032372	1.276317	1.945638	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000472
BRD-A98990573-003-01-3	ACH-000962	OC314_OVARY	HTS002	1	1.268094	0.141769	-0.025807	1.186686	0.00018	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000962
BRD-A98990573-003-01-3	ACH-000383	OE33_OESOPHAGUS	HTS002	1	1.678538	-0.009715	-0.097864	1.449327	97,223,179,148,416,700,000,000,000,000	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000383
BRD-A98990573-003-01-3	ACH-000824	KYSE510_OESOPHAGUS	HTS002	1	1.596906	0.17187	0.069866	1.26826	0.272332	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000824
BRD-A98990573-003-01-3	ACH-001307	8505C_THYROID	HTS002	1	2.038354	-0.171914	-0.084567	1.34439	0.00106	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-001307
BRD-A98990573-003-01-3	ACH-000756	GI1_CENTRAL_NERVOUS_SYSTEM	HTS002	1	1.764475	-2.489705	0.162361	1.514405	0.418282	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000756
BRD-A98990573-003-01-3	ACH-000681	A549_LUNG	HTS002	1	1.53699	0.175699	-0.032203	1.238485	0.302502	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000681
BRD-A98990573-003-01-3	ACH-000444	LU99_LUNG	HTS002	1	2.304853	-0.138791	0.014519	1.542931	0.00621	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000444
BRD-A98990573-003-01-3	ACH-000142	CAL29_URINARY_TRACT	HTS002	1	1.589938	0.055448	0.049684	1.29646	0.065032	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000142
BRD-A98990573-003-01-3	ACH-000905	5637_URINARY_TRACT	HTS002	1	1.569268	-0.133554	-0.048655	1.33827	1.498729	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000905
BRD-A98990573-003-01-3	ACH-000680	SW948_LARGE_INTESTINE	HTS002	1	1.426918	-0.072766	-0.019009	1.330106	1,911,848.939526	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000680
BRD-A98990573-003-01-3	ACH-000921	NCIH1339_LUNG	HTS002	1	1.741729	0.1469	0.082988	1.266817	4.644488	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000921
BRD-A98990573-003-01-3	ACH-000954	HEC1A_ENDOMETRIUM	HTS002	1	5.269249	-0.588912	-0.147595	1.229158	0.000108	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000954
BRD-A98990573-003-01-3	ACH-000280	SNU840_OVARY	HTS002	1	1.484033	0.149603	0.053609	1.286622	0.005805	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000280
BRD-A98990573-003-01-3	ACH-000012	HCC827_LUNG	HTS002	1	1.400204	-0.034575	-0.113861	1.211081	1.887026	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000012
BRD-A98990573-003-01-3	ACH-000098	GAMG_CENTRAL_NERVOUS_SYSTEM	HTS002	1	2.178352	-0.004613	-0.004302	1.596891	22.842661	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000098
BRD-A98990573-003-01-3	ACH-000589	NCIH1437_LUNG	HTS002	1	1.213516	0.020887	-0.036477	1.11289	0.000316	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000589
BRD-A98990573-003-01-3	ACH-000738	GB1_CENTRAL_NERVOUS_SYSTEM	HTS002	1	1.807115	-0.000607	-0.042844	1.457621	491,817,601,031,550,050,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000738
BRD-A98990573-003-01-3	ACH-000837	NCIH322_LUNG	HTS002	1	1.233324	0.09505	-0.001854	1.157891	0.000029	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000837
BRD-A98990573-003-01-3	ACH-000967	SNUC2A_LARGE_INTESTINE	HTS002	1	1.376957	-0.506343	0.146928	1.13233	0.013578	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000967
BRD-A98990573-003-01-3	ACH-000662	CORL23_LUNG	HTS002	1	1.716309	0.025663	-0.0267	1.368397	0.008382	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000662
BRD-A98990573-003-01-3	ACH-000537	SNU761_LIVER	HTS002	1	2.061626	-0.008197	-0.029404	1.51904	0.000348	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000537
BRD-A98990573-003-01-3	ACH-000427	NCIN87_STOMACH	HTS002	1	4.631994	0.217239	-0.172489	1.329703	6,213.220833	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000427
BRD-A98990573-003-01-3	ACH-000774	RERFLCAD2_LUNG	HTS002	1	0.869396	0.287087	-0.252837	0.921087	0.014259	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000774
BRD-A98990573-003-01-3	ACH-000624	HCC1806_BREAST	HTS002	1	1.358095	-0.037473	-0.097946	1.244311	59,167,917.654693	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000624
BRD-A98990573-003-01-3	ACH-000888	NCIH1793_LUNG	HTS002	1	1.747051	-0.158062	-0.099354	1.208049	0.000144	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000888
BRD-A98990573-003-01-3	ACH-000449	MESSA_SOFT_TISSUE	HTS002	1	1.86262	-0.283023	-0.057474	1.423596	0.067535	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000449
BRD-A98990573-003-01-3	ACH-000587	NCIH1975_LUNG	HTS002	1	1.847677	0.109223	-0.019453	1.365985	1.024207	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000587
BRD-A98990573-003-01-3	ACH-000813	T3M10_LUNG	HTS002	1	1.635919	0.111035	-0.063444	1.437736	0.000053	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000813
BRD-A98990573-003-01-3	ACH-000311	NCIH2122_LUNG	HTS002	1	1.85451	-0.017644	-0.072545	1.421462	0.016784	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000311
BRD-A98990573-003-01-3	ACH-000849	MDAMB468_BREAST	HTS002	1	2.273915	-0.081424	-0.094399	1.603123	0.020809	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000849
BRD-A98990573-003-01-3	ACH-000868	HCC1195_LUNG	HTS002	1	2.83362	0.459477	0.029263	1.368293	4.192163	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000868
BRD-A98990573-003-01-3	ACH-000978	EN_ENDOMETRIUM	HTS002	1	1.270689	0.121753	-0.022117	1.167954	0.00123	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000978
BRD-A98990573-003-01-3	ACH-000408	TE5_OESOPHAGUS	HTS002	1	1.733935	0.079685	-0.048411	1.322106	1.772561	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000408
BRD-A98990573-003-01-3	ACH-000344	SNU668_STOMACH	HTS002	1	1.576349	-0.043401	0.014684	1.30125	0.63807	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000344
BRD-A98990573-003-01-3	ACH-000161	CORL105_LUNG	HTS002	1	1.822872	0.10402	-0.051185	1.38221	0.31584	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000161
BRD-A98990573-003-01-3	ACH-000819	LN18_CENTRAL_NERVOUS_SYSTEM	HTS002	1	1.7915	0.084356	-0.056295	1.479936	0.000434	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000819
BRD-A98990573-003-01-3	ACH-000062	RERFLCMS_LUNG	HTS002	1	1.939114	0.378691	-0.046393	1.501106	0.049814	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000062
BRD-A98990573-003-01-3	ACH-000473	RT112_URINARY_TRACT	HTS002	1	1.39427	0.046351	-0.03644	1.187842	0.603376	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000473
BRD-A98990573-003-01-3	ACH-000176	LOUNH91_LUNG	HTS002	1	1.235706	-0.002682	-0.160774	1.123029	13,417,069,888,149.4	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000176
BRD-A98990573-003-01-3	ACH-000331	ISTMES2_PLEURA	HTS002	1	1.344105	0.082575	0.001573	1.216917	0.000112	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000331
BRD-A98990573-003-01-3	ACH-000163	SW579_THYROID	HTS002	1	1.439338	-0.092099	-0.032339	1.322894	5,965.899147	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000163
BRD-A98990573-003-01-3	ACH-000768	MDAMB231_BREAST	HTS002	1	2.706713	0.197872	-0.091837	1.574705	3.082576	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000768
BRD-A98990573-003-01-3	null	null	HTS002	1	1.80926	-0.041348	-0.039745	1.458301	50.699151	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	false	ACH-001078_FAILED_STR
BRD-A98990573-003-01-3	ACH-000778	HSC3_UPPER_AERODIGESTIVE_TRACT	HTS002	1	1.583385	0.007099	0.011829	1.291322	0.111731	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000778
BRD-A98990573-003-01-3	ACH-000881	MELJUSO_SKIN	HTS002	1	1.888164	-0.114702	-0.024283	1.366211	0.003288	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000881
BRD-A98990573-003-01-3	ACH-000521	NCIH2030_LUNG	HTS002	1	2.24455	-0.077862	0.003723	1.479991	0.000184	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000521
BRD-A98990573-003-01-3	ACH-000696	OVCAR8_OVARY	HTS002	1	1.879834	0.086434	-0.054792	1.372949	2.863434	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000696
BRD-A98990573-003-01-3	ACH-000972	HEC151_ENDOMETRIUM	HTS002	1	1.463268	0.020475	-0.059265	1.240387	0.001939	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000972
BRD-A98990573-003-01-3	ACH-000242	RT4_URINARY_TRACT	HTS002	1	1.622187	-0.265336	-0.002719	1.35207	0.242349	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000242
BRD-A98990573-003-01-3	ACH-000087	SKES1_BONE	HTS002	1	2.693394	0.667153	0.08876	1.20362	7.781999	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000087
BRD-A98990573-003-01-3	ACH-000926	HT55_LARGE_INTESTINE	HTS002	1	2.176831	0.242024	-0.050506	1.304718	9.40063	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000926
BRD-A98990573-003-01-3	ACH-000356	MKN45_STOMACH	HTS002	1	2.337874	-0.066451	0.037995	1.575769	0.001108	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000356
BRD-A98990573-003-01-3	ACH-000625	HEP3B217_LIVER	HTS002	1	1.096657	-0.095026	-0.053177	1.059739	13.50321	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000625
BRD-A98990573-003-01-3	ACH-000613	HOS_BONE	HTS002	1	1.652513	0.085862	-0.032443	1.368031	0.00373	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000613
BRD-A98990573-003-01-3	ACH-000976	HUCCT1_BILIARY_TRACT	HTS002	1	1.798369	-0.080298	0.009857	1.434595	0.736189	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000976
BRD-A98990573-003-01-3	ACH-001075	NCIH292_LUNG	HTS002	1	1.820811	0.180107	0.045467	1.467709	0.014883	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-001075
BRD-A98990573-003-01-3	ACH-000261	RERFLCAI_LUNG	HTS002	1	1.569389	0.045662	0.002589	1.274034	0.405779	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000261
BRD-A98990573-003-01-3	ACH-000573	MDAMB436_BREAST	HTS002	1	1.181591	-0.332248	-0.055078	1.085108	0.049523	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000573
BRD-A98990573-003-01-3	ACH-000852	NCIH1435_LUNG	HTS002	1	1.703564	0.392353	-0.016434	1.283407	0.282568	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000852
BRD-A98990573-003-01-3	ACH-000461	SNU1196_BILIARY_TRACT	HTS002	1	2.588125	0.207174	0.213909	1.503049	4.277746	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000461
BRD-A98990573-003-01-3	ACH-000420	SNU449_LIVER	HTS002	1	1.731601	-0.028169	-0.028294	1.356452	0.012686	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000420
BRD-A98990573-003-01-3	ACH-000694	TE9_OESOPHAGUS	HTS002	1	1.898467	-0.183489	0.037068	1.353043	0.006269	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000694
BRD-A98990573-003-01-3	ACH-000528	ABC1_LUNG	HTS002	1	1.543349	-1.240617	0.355513	1.454126	2.291496	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000528
BRD-A98990573-003-01-3	ACH-000845	NCIH1373_LUNG	HTS002	1	1.624379	-0.037358	-0.055001	1.305831	0.026174	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000845
BRD-A98990573-003-01-3	ACH-000563	EBC1_LUNG	HTS002	1	2.320926	0.188521	0.183644	1.46427	2.500192	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000563
BRD-A98990573-003-01-3	ACH-000296	OUMS23_LARGE_INTESTINE	HTS002	1	2.670125	-0.191569	0.021708	1.520029	0.000938	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000296
BRD-A98990573-003-01-3	ACH-000189	RCC10RGB_KIDNEY	HTS002	1	1.945365	0.175818	0.072348	1.409851	0.391496	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000189
BRD-A98990573-003-01-3	ACH-000791	RERFLCAD1_LUNG	HTS002	1	1.743939	0.029754	-0.028777	1.384235	0.008476	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000791

BRD-A98990573-003-01-3

ACH-000480

HUH7_LIVER

HTS002

1

1.324224

-0.128318

-0.122661

1.2024

4.62325

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000480

BRD-A98990573-003-01-3

ACH-000281

KP2_PANCREAS

HTS002

1

15.510764

2.295423

-0.321783

1.000001

3,612.317274

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000281

BRD-A98990573-003-01-3

ACH-000897

FTC238_THYROID

HTS002

1

1.835751

-0.015413

0.001432

1.54188

13,887,541,600,055,404

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000897

BRD-A98990573-003-01-3

ACH-000389

H4_CENTRAL_NERVOUS_SYSTEM

HTS002

1

1.561929

-0.096359

-0.028321

1.448968

162,102.794614

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000389

BRD-A98990573-003-01-3

ACH-000862

KMBC2_URINARY_TRACT

HTS002

1

1.521251

-0.061001

0.021827

1.284177

1.557338

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000862

BRD-A98990573-003-01-3

ACH-000776

ONS76_CENTRAL_NERVOUS_SYSTEM

HTS002

1

1.423457

-0.12339

-0.024998

1.249453

1.576824

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000776

BRD-A98990573-003-01-3

ACH-000023

PATU8988T_PANCREAS

HTS002

1

1.620223

-0.264201

0.146633

1.255104

0.016815

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000023

BRD-A98990573-003-01-3

ACH-000011

253J_URINARY_TRACT

HTS002

1

1.564166

0.099456

-0.032355

1.301252

0.019361

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000011

BRD-A98990573-003-01-3

ACH-000973

639V_URINARY_TRACT

HTS002

1

1.741875

-0.081131

0.001129

1.396441

0.436023

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000973

BRD-A98990573-003-01-3

ACH-001024

CHL1_SKIN

HTS002

1

1.813534

-0.167312

0.026972

1.416792

0.106589

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-001024

BRD-A98990573-003-01-3

ACH-000971

HCT116_LARGE_INTESTINE

HTS002

1

1.288773

1.08576

-0.10527

1.248526

0.001855

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000971

BRD-A98990573-003-01-3

ACH-000486

KU1919_URINARY_TRACT

HTS002

1

1.374036

-0.222058

-0.073943

1.273026

10.176591

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000486

BRD-A98990573-003-01-3

ACH-000997

HCT15_LARGE_INTESTINE

HTS002

1

1.508362

0.085375

0.022693

1.263036

0.034134

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000997

BRD-A98990573-003-01-3

ACH-000552

HT29_LARGE_INTESTINE

HTS002

1

1.623043

-0.081142

0.000514

1.515596

23,833,677.253788

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000552

BRD-A98990573-003-01-3

ACH-000796

MCAS_OVARY

HTS002

1

1.33417

0.010324

-0.033116

1.165521

0.479242

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000796

BRD-A98990573-003-01-3

ACH-000652

SUIT2_PANCREAS

HTS002

1

1.632154

-0.039386

-0.003732

1.352823

29.930865

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000652

BRD-A98990573-003-01-3

ACH-000452

TE8_OESOPHAGUS

HTS002

1

1.484911

0.165505

-0.038621

1.287723

0.007067

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000452

BRD-A98990573-003-01-3

ACH-000458

CJM_SKIN

HTS002

1

1.74168

-0.013627

-0.002435

1.444336

499,942,726,627.35

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000458

BRD-A98990573-003-01-3

ACH-000221

SNU398_LIVER

HTS002

1

2.417817

0.066095

-0.013351

1.642478

1.37533

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000221

BRD-A98990573-003-01-3

ACH-000970

SNUC5_LARGE_INTESTINE

HTS002

1

2.017877

-0.317641

0.021475

1.531059

0.108233

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000970

BRD-A98990573-003-01-3

ACH-000893

NCIH1651_LUNG

HTS002

1

1.482333

0.164283

-0.075208

1.377909

0.000022

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000893

BRD-A98990573-003-01-3

ACH-000562

HCC78_LUNG

HTS002

1

1.872368

0.103596

0.033422

1.314313

22.310079

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000562

BRD-A98990573-003-01-3

ACH-000769

LK2_LUNG

HTS002

1

1.840631

0.139391

0.026816

1.376077

0.376606

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000769

BRD-A98990573-003-01-3

ACH-000858

KNS62_LUNG

HTS002

1

1.521935

-0.002187

-0.001344

1.302639

708,545,613,969,306,050,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000858

BRD-A98990573-003-01-3

ACH-000595

LN229_CENTRAL_NERVOUS_SYSTEM

HTS002

1

2.130337

0.288872

0.141273

1.502528

0.190659

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000595

BRD-A98990573-003-01-3

ACH-000052

A673_BONE

HTS002

1

1.983414

-0.14041

0.000037

1.374243

0.002134

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000052

BRD-A98990573-003-01-3

ACH-000979

DU145_PROSTATE

HTS002

1

1.585481

0.293565

0.052222

1.158138

3.842981

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000979

BRD-A98990573-003-01-3

ACH-000571

T98G_CENTRAL_NERVOUS_SYSTEM

HTS002

1

1.398819

0.050182

-0.02024

1.212443

0.005678

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000571

BRD-A98990573-003-01-3

ACH-000812

COLO783_SKIN

HTS002

1

1.554188

-0.113242

-0.009886

1.273885

0.063346

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000812

BRD-A98990573-003-01-3

ACH-000891

HCC1438_LUNG

HTS002

1

1.680534

0.065755

0.021049

1.391383

0.000752

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000891

BRD-A98990573-003-01-3

ACH-000802

BFTC905_URINARY_TRACT

HTS002

1

1.515346

0.27546

0.011442

1.241738

0.130686

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000802

BRD-A98990573-003-01-3

ACH-000472

HSC2_UPPER_AERODIGESTIVE_TRACT

HTS002

1

1.456211

-0.138394

0.032372

1.276317

1.945638

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000472

BRD-A98990573-003-01-3

ACH-000962

OC314_OVARY

HTS002

1

1.268094

0.141769

-0.025807

1.186686

0.00018

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000962

BRD-A98990573-003-01-3

ACH-000383

OE33_OESOPHAGUS

HTS002

1

1.678538

-0.009715

-0.097864

1.449327

97,223,179,148,416,700,000,000,000,000

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000383

BRD-A98990573-003-01-3

ACH-000824

KYSE510_OESOPHAGUS

HTS002

1

1.596906

0.17187

0.069866

1.26826

0.272332

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000824

BRD-A98990573-003-01-3

ACH-001307

8505C_THYROID

HTS002

1

2.038354

-0.171914

-0.084567

1.34439

0.00106

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-001307

BRD-A98990573-003-01-3

ACH-000756

GI1_CENTRAL_NERVOUS_SYSTEM

HTS002

1

1.764475

-2.489705

0.162361

1.514405

0.418282

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000756

BRD-A98990573-003-01-3

ACH-000681

A549_LUNG

HTS002

1

1.53699

0.175699

-0.032203

1.238485

0.302502

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000681

BRD-A98990573-003-01-3

ACH-000444

LU99_LUNG

HTS002

1

2.304853

-0.138791

0.014519

1.542931

0.00621

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000444

BRD-A98990573-003-01-3

ACH-000142

CAL29_URINARY_TRACT

HTS002

1

1.589938

0.055448

0.049684

1.29646

0.065032

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000142

BRD-A98990573-003-01-3

ACH-000905

5637_URINARY_TRACT

HTS002

1

1.569268

-0.133554

-0.048655

1.33827

1.498729

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000905

BRD-A98990573-003-01-3

ACH-000680

SW948_LARGE_INTESTINE

HTS002

1

1.426918

-0.072766

-0.019009

1.330106

1,911,848.939526

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000680

BRD-A98990573-003-01-3

ACH-000921

NCIH1339_LUNG

HTS002

1

1.741729

0.1469

0.082988

1.266817

4.644488

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000921

BRD-A98990573-003-01-3

ACH-000954

HEC1A_ENDOMETRIUM

HTS002

1

5.269249

-0.588912

-0.147595

1.229158

0.000108

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000954

BRD-A98990573-003-01-3

ACH-000280

SNU840_OVARY

HTS002

1

1.484033

0.149603

0.053609

1.286622

0.005805

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000280

BRD-A98990573-003-01-3

ACH-000012

HCC827_LUNG

HTS002

1

1.400204

-0.034575

-0.113861

1.211081

1.887026

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000012

BRD-A98990573-003-01-3

ACH-000098

GAMG_CENTRAL_NERVOUS_SYSTEM

HTS002

1

2.178352

-0.004613

-0.004302

1.596891

22.842661

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000098

BRD-A98990573-003-01-3

ACH-000589

NCIH1437_LUNG

HTS002

1

1.213516

0.020887

-0.036477

1.11289

0.000316

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000589

BRD-A98990573-003-01-3

ACH-000738

GB1_CENTRAL_NERVOUS_SYSTEM

HTS002

1

1.807115

-0.000607

-0.042844

1.457621

491,817,601,031,550,050,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000,000

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000738

BRD-A98990573-003-01-3

ACH-000837

NCIH322_LUNG

HTS002

1

1.233324

0.09505

-0.001854

1.157891

0.000029

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000837

BRD-A98990573-003-01-3

ACH-000967

SNUC2A_LARGE_INTESTINE

HTS002

1

1.376957

-0.506343

0.146928

1.13233

0.013578

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000967

BRD-A98990573-003-01-3

ACH-000662

CORL23_LUNG

HTS002

1

1.716309

0.025663

-0.0267

1.368397

0.008382

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000662

BRD-A98990573-003-01-3

ACH-000537

SNU761_LIVER

HTS002

1

2.061626

-0.008197

-0.029404

1.51904

0.000348

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000537

BRD-A98990573-003-01-3

ACH-000427

NCIN87_STOMACH

HTS002

1

4.631994

0.217239

-0.172489

1.329703

6,213.220833

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000427

BRD-A98990573-003-01-3

ACH-000774

RERFLCAD2_LUNG

HTS002

1

0.869396

0.287087

-0.252837

0.921087

0.014259

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000774

BRD-A98990573-003-01-3

ACH-000624

HCC1806_BREAST

HTS002

1

1.358095

-0.037473

-0.097946

1.244311

59,167,917.654693

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000624

BRD-A98990573-003-01-3

ACH-000888

NCIH1793_LUNG

HTS002

1

1.747051

-0.158062

-0.099354

1.208049

0.000144

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000888

BRD-A98990573-003-01-3

ACH-000449

MESSA_SOFT_TISSUE

HTS002

1

1.86262

-0.283023

-0.057474

1.423596

0.067535

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000449

BRD-A98990573-003-01-3

ACH-000587

NCIH1975_LUNG

HTS002

1

1.847677

0.109223

-0.019453

1.365985

1.024207

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000587

BRD-A98990573-003-01-3

ACH-000813

T3M10_LUNG

HTS002

1

1.635919

0.111035

-0.063444

1.437736

0.000053

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000813

BRD-A98990573-003-01-3

ACH-000311

NCIH2122_LUNG

HTS002

1

1.85451

-0.017644

-0.072545

1.421462

0.016784

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000311

BRD-A98990573-003-01-3

ACH-000849

MDAMB468_BREAST

HTS002

1

2.273915

-0.081424

-0.094399

1.603123

0.020809

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000849

BRD-A98990573-003-01-3

ACH-000868

HCC1195_LUNG

HTS002

1

2.83362

0.459477

0.029263

1.368293

4.192163

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000868

BRD-A98990573-003-01-3

ACH-000978

EN_ENDOMETRIUM

HTS002

1

1.270689

0.121753

-0.022117

1.167954

0.00123

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000978

BRD-A98990573-003-01-3

ACH-000408

TE5_OESOPHAGUS

HTS002

1

1.733935

0.079685

-0.048411

1.322106

1.772561

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000408

BRD-A98990573-003-01-3

ACH-000344

SNU668_STOMACH

HTS002

1

1.576349

-0.043401

0.014684

1.30125

0.63807

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000344

BRD-A98990573-003-01-3

ACH-000161

CORL105_LUNG

HTS002

1

1.822872

0.10402

-0.051185

1.38221

0.31584

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000161

BRD-A98990573-003-01-3

ACH-000819

LN18_CENTRAL_NERVOUS_SYSTEM

HTS002

1

1.7915

0.084356

-0.056295

1.479936

0.000434

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000819

BRD-A98990573-003-01-3

ACH-000062

RERFLCMS_LUNG

HTS002

1

1.939114

0.378691

-0.046393

1.501106

0.049814

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000062

BRD-A98990573-003-01-3

ACH-000473

RT112_URINARY_TRACT

HTS002

1

1.39427

0.046351

-0.03644

1.187842

0.603376

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000473

BRD-A98990573-003-01-3

ACH-000176

LOUNH91_LUNG

HTS002

1

1.235706

-0.002682

-0.160774

1.123029

13,417,069,888,149.4

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000176

BRD-A98990573-003-01-3

ACH-000331

ISTMES2_PLEURA

HTS002

1

1.344105

0.082575

0.001573

1.216917

0.000112

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000331

BRD-A98990573-003-01-3

ACH-000163

SW579_THYROID

HTS002

1

1.439338

-0.092099

-0.032339

1.322894

5,965.899147

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000163

BRD-A98990573-003-01-3

ACH-000768

MDAMB231_BREAST

HTS002

1

2.706713

0.197872

-0.091837

1.574705

3.082576

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000768

BRD-A98990573-003-01-3

null

HTS002

1

1.80926

-0.041348

-0.039745

1.458301

50.699151

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

false

ACH-001078_FAILED_STR

BRD-A98990573-003-01-3

ACH-000778

HSC3_UPPER_AERODIGESTIVE_TRACT

HTS002

1

1.583385

0.007099

0.011829

1.291322

0.111731

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000778

BRD-A98990573-003-01-3

ACH-000881

MELJUSO_SKIN

HTS002

1

1.888164

-0.114702

-0.024283

1.366211

0.003288

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000881

BRD-A98990573-003-01-3

ACH-000521

NCIH2030_LUNG

HTS002

1

2.24455

-0.077862

0.003723

1.479991

0.000184

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000521

BRD-A98990573-003-01-3

ACH-000696

OVCAR8_OVARY

HTS002

1

1.879834

0.086434

-0.054792

1.372949

2.863434

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000696

BRD-A98990573-003-01-3

ACH-000972

HEC151_ENDOMETRIUM

HTS002

1

1.463268

0.020475

-0.059265

1.240387

0.001939

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000972

BRD-A98990573-003-01-3

ACH-000242

RT4_URINARY_TRACT

HTS002

1

1.622187

-0.265336

-0.002719

1.35207

0.242349

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000242

BRD-A98990573-003-01-3

ACH-000087

SKES1_BONE

HTS002

1

2.693394

0.667153

0.08876

1.20362

7.781999

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000087

BRD-A98990573-003-01-3

ACH-000926

HT55_LARGE_INTESTINE

HTS002

1

2.176831

0.242024

-0.050506

1.304718

9.40063

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000926

BRD-A98990573-003-01-3

ACH-000356

MKN45_STOMACH

HTS002

1

2.337874

-0.066451

0.037995

1.575769

0.001108

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000356

BRD-A98990573-003-01-3

ACH-000625

HEP3B217_LIVER

HTS002

1

1.096657

-0.095026

-0.053177

1.059739

13.50321

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000625

BRD-A98990573-003-01-3

ACH-000613

HOS_BONE

HTS002

1

1.652513

0.085862

-0.032443

1.368031

0.00373

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000613

BRD-A98990573-003-01-3

ACH-000976

HUCCT1_BILIARY_TRACT

HTS002

1

1.798369

-0.080298

0.009857

1.434595

0.736189

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000976

BRD-A98990573-003-01-3

ACH-001075

NCIH292_LUNG

HTS002

1

1.820811

0.180107

0.045467

1.467709

0.014883

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-001075

BRD-A98990573-003-01-3

ACH-000261

RERFLCAI_LUNG

HTS002

1

1.569389

0.045662

0.002589

1.274034

0.405779

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000261

BRD-A98990573-003-01-3

ACH-000573

MDAMB436_BREAST

HTS002

1

1.181591

-0.332248

-0.055078

1.085108

0.049523

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000573

BRD-A98990573-003-01-3

ACH-000852

NCIH1435_LUNG

HTS002

1

1.703564

0.392353

-0.016434

1.283407

0.282568

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000852

BRD-A98990573-003-01-3

ACH-000461

SNU1196_BILIARY_TRACT

HTS002

1

2.588125

0.207174

0.213909

1.503049

4.277746

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000461

BRD-A98990573-003-01-3

ACH-000420

SNU449_LIVER

HTS002

1

1.731601

-0.028169

-0.028294

1.356452

0.012686

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000420

BRD-A98990573-003-01-3

ACH-000694

TE9_OESOPHAGUS

HTS002

1

1.898467

-0.183489

0.037068

1.353043

0.006269

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000694

BRD-A98990573-003-01-3

ACH-000528

ABC1_LUNG

HTS002

1

1.543349

-1.240617

0.355513

1.454126

2.291496

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000528

BRD-A98990573-003-01-3

ACH-000845

NCIH1373_LUNG

HTS002

1

1.624379

-0.037358

-0.055001

1.305831

0.026174

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000845

BRD-A98990573-003-01-3

ACH-000563

EBC1_LUNG

HTS002

1

2.320926

0.188521

0.183644

1.46427

2.500192

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000563

BRD-A98990573-003-01-3

ACH-000296

OUMS23_LARGE_INTESTINE

HTS002

1

2.670125

-0.191569

0.021708

1.520029

0.000938

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000296

BRD-A98990573-003-01-3

ACH-000189

RCC10RGB_KIDNEY

HTS002

1

1.945365

0.175818

0.072348

1.409851

0.391496

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000189

BRD-A98990573-003-01-3

ACH-000791

RERFLCAD1_LUNG

HTS002

1

1.743939

0.029754

-0.028777

1.384235

0.008476

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000791