donb-hf/secondary-screen-dose-response-curve-parameters

broad_id string	depmap_id string	ccle_name string	screen_id string	upper_limit int64	lower_limit float64	slope float64	r2 float64	auc float64	ec50 float64	ic50 float64	name string	moa string	target string	disease.area string	indication string	smiles string	phase string	passed_str_profiling bool	row_name string
BRD-A98990573-003-01-3	ACH-000650	IGR37_SKIN	HTS002	1	1.820349	-0.024736	-0.297873	1.420808	0.637424	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000650
BRD-A98990573-003-01-3	ACH-000748	SJSA1_BONE	HTS002	1	1.629373	-0.022834	-0.003305	1.367757	237,882.528641	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000748
BRD-A98990573-003-01-3	ACH-000788	A2058_SKIN	HTS002	1	1.556304	-0.241323	0.299702	1.227845	0.014518	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000788
BRD-A98990573-003-01-3	ACH-000545	VMCUB1_URINARY_TRACT	HTS002	1	0.730028	-2.439885	-0.209177	0.904544	0.018865	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000545
BRD-A98990573-003-01-3	ACH-000762	YD38_UPPER_AERODIGESTIVE_TRACT	HTS002	1	2.018194	-0.125205	-0.058569	1.619976	2.981759	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000762
BRD-A98990573-003-01-3	ACH-000211	DAOY_CENTRAL_NERVOUS_SYSTEM	HTS002	1	1.830988	-0.144544	0.048558	1.327476	0.003536	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000211
BRD-A98990573-003-01-3	ACH-000936	EFO27_OVARY	HTS002	1	1.838278	-0.062131	0.015137	1.364389	0.001102	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000936
BRD-A98990573-003-01-3	ACH-000882	IGR1_SKIN	HTS002	1	1.783593	0.09278	0.082606	1.267679	103.296555	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000882
BRD-A98990573-003-01-3	ACH-000471	LI7_LIVER	HTS002	1	1.533157	0.505352	0.058605	1.34906	0.012633	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000471
BRD-A98990573-003-01-3	ACH-000670	SBC5_LUNG	HTS002	1	1.368531	-0.258409	0.075831	1.147542	0.013438	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000670
BRD-A98990573-003-01-3	ACH-000048	TOV112D_OVARY	HTS002	1	1.550195	0.063352	-0.071279	1.321229	0.000358	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000048
BRD-A98990573-003-01-3	ACH-000259	KELLY_AUTONOMIC_GANGLIA	HTS002	1	1.515884	-0.109124	-0.036485	1.227478	0.008442	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000259
BRD-A98990573-003-01-3	ACH-000599	PATU8902_PANCREAS	HTS002	1	1.697333	-0.0204	-0.053723	1.376231	185.683349	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000599
BRD-A98990573-003-01-3	ACH-000716	TT2609C02_THYROID	HTS002	1	1.638413	0.003429	-0.008691	1.317777	1.064217	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000716
BRD-A98990573-003-01-3	ACH-000347	QGP1_PANCREAS	HTS002	1	1.566898	-0.433016	0.009184	1.14365	0.002978	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000347
BRD-A98990573-003-01-3	ACH-000566	SW1710_URINARY_TRACT	HTS002	1	1.350184	0.069992	-0.053704	1.203651	0.000678	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000566
BRD-A98990573-003-01-3	ACH-001016	BECKER_CENTRAL_NERVOUS_SYSTEM	HTS002	1	1.361135	-0.310624	0.065313	1.243253	1.208025	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-001016
BRD-A98990573-003-01-3	ACH-000395	NCIH520_LUNG	HTS002	1	1.436174	-0.097299	-0.027539	1.256566	3.263453	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000395
BRD-A98990573-003-01-3	ACH-000407	SNU685_ENDOMETRIUM	HTS002	1	1.945127	0.090783	-0.01996	1.492706	0.030072	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000407
BRD-A98990573-003-01-3	ACH-000418	SW1353_BONE	HTS002	1	3.419838	-0.114436	-0.015998	2.132578	0.024805	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000418
BRD-A98990573-003-01-3	ACH-000008	A101D_SKIN	HTS002	1	1.501761	0.218633	0.006067	1.202753	0.542737	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000008
BRD-A98990573-003-01-3	ACH-000191	BHT101_THYROID	HTS002	1	1.609186	-0.123199	-0.075613	1.345817	0.760553	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000191
BRD-A98990573-003-01-3	ACH-000941	HEC1B_ENDOMETRIUM	HTS002	1	1.527177	-0.042788	-0.050364	1.254625	0.015838	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000941
BRD-A98990573-003-01-3	ACH-000532	SNU61_LARGE_INTESTINE	HTS002	1	2.091377	-0.042439	-0.004104	1.576969	1.178751	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000532
BRD-A98990573-003-01-3	ACH-000316	SNU886_LIVER	HTS002	1	1.593947	0.129343	0.071052	1.254468	0.779699	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000316
BRD-A98990573-003-01-3	ACH-000677	SW1573_LUNG	HTS002	1	1.67553	0.131864	-0.009404	1.256825	3.59763	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000677
BRD-A98990573-003-01-3	ACH-000210	CADOES1_BONE	HTS002	1	1.448094	-0.249945	0.021653	1.091691	0.000195	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000210
BRD-A98990573-003-01-3	ACH-000803	COLO668_LUNG	HTS002	1	1.765142	0.098226	-0.108707	1.511044	0.000056	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000803
BRD-A98990573-003-01-3	ACH-000007	LS513_LARGE_INTESTINE	HTS002	1	2.04869	0.11884	-0.052451	1.43607	1.475633	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000007
BRD-A98990573-003-01-3	ACH-000719	RMGI_OVARY	HTS002	1	1.231354	-0.054457	-0.083873	1.194003	1,242,980,391,363.15	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000719
BRD-A98990573-003-01-3	ACH-000484	VMRCRCW_KIDNEY	HTS002	1	1.545587	0.007846	-0.008949	1.271739	0.209228	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000484
BRD-A98990573-003-01-3	ACH-000433	CAKI1_KIDNEY	HTS002	1	1.830107	-0.045053	-0.094601	1.387762	0.004152	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000433
BRD-A98990573-003-01-3	ACH-000688	OV7_OVARY	HTS002	1	2.525953	0.029149	-0.019781	1.817195	0.000586	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000688
BRD-A98990573-003-01-3	ACH-000603	BEN_LUNG	HTS002	1	1.58366	0.013974	0.008093	1.261426	248,022.635199	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000603
BRD-A98990573-003-01-3	ACH-000351	MKN1_STOMACH	HTS002	1	1.70352	-0.260435	0.05367	1.304682	0.024315	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000351
BRD-A98990573-003-01-3	ACH-000627	LCLC103H_LUNG	HTS002	1	2.170173	0.142362	-0.004723	1.250698	987.354029	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000627
BRD-A98990573-003-01-3	ACH-000916	NCIH1573_LUNG	HTS002	1	2.311052	0.006035	0.004773	1.656346	0.051606	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000916
BRD-A98990573-003-01-3	ACH-000863	DBTRG05MG_CENTRAL_NERVOUS_SYSTEM	HTS002	1	1.635168	0.069947	-0.169209	1.394398	0.000063	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000863
BRD-A98990573-003-01-3	ACH-000066	HCC4006_LUNG	HTS002	1	1.322655	-0.017401	0.000458	1.173943	640.458479	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000066
BRD-A98990573-003-01-3	ACH-000015	NCIH1581_LUNG	HTS002	1	1.536849	0.165862	-0.24244	1.200193	2.112639	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000015
BRD-A98990573-003-01-3	null	null	HTS002	1	1.713302	-0.092802	-0.156442	1.371913	0.199668	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	false	ACH-000511_FAILED_STR
BRD-A98990573-003-01-3	ACH-000674	NUGC4_STOMACH	HTS002	1	1.763321	-0.468645	0.649527	1.333147	0.0365	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000674
BRD-A98990573-003-01-3	ACH-000892	NCIH1563_LUNG	HTS002	1	1.081033	-0.349447	0.004121	1.014616	0.00045	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000892
BRD-A98990573-003-01-3	ACH-000909	JHUEM2_ENDOMETRIUM	HTS002	1	1.668088	0.299063	0.020538	1.30189	0.166195	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000909
BRD-A98990573-003-01-3	ACH-000237	JHOM1_OVARY	HTS002	1	1.619702	-0.19998	-0.034923	1.323298	0.124729	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000237
BRD-A98990573-003-01-3	ACH-000811	SKOV3_OVARY	HTS002	1	1.755043	-0.048146	-0.048229	1.431482	31.690909	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000811
BRD-A98990573-003-01-3	ACH-000312	SKNBE2_AUTONOMIC_GANGLIA	HTS002	1	1.576632	-0.076188	-0.052859	1.291012	0.100139	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000312
BRD-A98990573-003-01-3	ACH-000901	HCC1359_LUNG	HTS002	1	1.907709	0.093215	-0.115198	1.278326	569.579826	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000901
BRD-A98990573-003-01-3	ACH-000289	SNU466_CENTRAL_NERVOUS_SYSTEM	HTS002	1	2.014481	-0.36223	-0.038471	1.080091	0.000029	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000289
BRD-A98990573-003-01-3	ACH-000733	NCIH1838_LUNG	HTS002	1	1.855177	0.043852	-0.012144	1.500318	0.00003	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000733
BRD-A98990573-003-01-3	ACH-000268	SNU245_BILIARY_TRACT	HTS002	1	3.019335	0.145389	-0.006777	1.601176	35.950204	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000268
BRD-A98990573-003-01-3	ACH-000758	MKN74_STOMACH	HTS002	1	1.753247	0.067618	-0.117205	1.201335	264,905.16381	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000758
BRD-A98990573-003-01-3	ACH-000693	KYSE180_OESOPHAGUS	HTS002	1	1.433797	-0.512194	0.110691	1.376238	11.132484	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000693
BRD-A98990573-003-01-3	ACH-000264	CALU6_LUNG	HTS002	1	1.490461	-0.034016	0.007249	1.271417	43.264337	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000264
BRD-A98990573-003-01-3	ACH-000027	GOS3_CENTRAL_NERVOUS_SYSTEM	HTS002	1	1.780976	0.002659	-0.008845	1.380583	15,123,858.959958	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000027
BRD-A98990573-003-01-3	ACH-000720	TCCSUP_URINARY_TRACT	HTS002	1	2.198203	-0.414899	0.305273	1.387095	0.007678	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000720
BRD-A98990573-003-01-3	ACH-000814	HS939T_SKIN	HTS002	1	1.089522	0.350289	-0.087846	1.073917	0.000398	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000814
BRD-A98990573-003-01-3	ACH-000885	TOV21G_OVARY	HTS002	1	1.446876	-0.015603	-0.097006	1.310256	5,392,312,553,618,920,000,000	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000885
BRD-A98990573-003-01-3	ACH-000663	OVTOKO_OVARY	HTS002	1	1.512865	0.023007	-0.026331	1.201196	14,546,468.52015	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000663
BRD-A98990573-003-01-3	ACH-000647	TE1_OESOPHAGUS	HTS002	1	1.140966	-0.112351	-0.167108	1.110303	8,887.776362	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000647
BRD-A98990573-003-01-3	ACH-000243	DANG_PANCREAS	HTS002	1	2.06798	0.023153	-0.05191	1.48485	228.312576	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000243
BRD-A98990573-003-01-3	ACH-000255	LMSU_STOMACH	HTS002	1	1.694342	-0.174073	-0.048759	1.36352	0.138591	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000255
BRD-A98990573-003-01-3	ACH-000335	MSTO211H_PLEURA	HTS002	1	1.611948	0.242362	0.046093	1.163893	7.613375	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000335
BRD-A98990573-003-01-3	ACH-000147	T47D_BREAST	HTS002	1	1.515829	0.438492	0.221054	1.282377	0.043484	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000147
BRD-A98990573-003-01-3	ACH-000090	PC3_PROSTATE	HTS002	1	1.394236	0.025992	-0.000826	1.204897	0.003728	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000090
BRD-A98990573-003-01-3	ACH-000171	VMRCRCZ_KIDNEY	HTS002	1	2.656364	0.187366	0.304236	1.728065	0.311903	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000171
BRD-A98990573-003-01-3	ACH-000614	RVH421_SKIN	HTS002	1	1.272173	-0.052696	-0.098616	1.214494	5,870,546,788.39555	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000614
BRD-A98990573-003-01-3	ACH-000132	JHOS2_OVARY	HTS002	1	2.230741	0.325283	0.221803	1.396745	1.183204	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000132
BRD-A98990573-003-01-3	ACH-000274	HS852T_SKIN	HTS002	1	1.47399	-0.479815	0.057247	1.142754	0.006838	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000274
BRD-A98990573-003-01-3	null	null	HTS002	1	1.750228	0.201317	-0.000113	1.29669	0.756598	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	false	ACH-000807_FAILED_STR
BRD-A98990573-003-01-3	ACH-000810	SKMEL30_SKIN	HTS002	1	2.472409	-0.199165	0.152451	1.618257	0.01363	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000810
BRD-A98990573-003-01-3	ACH-000022	PATU8988S_PANCREAS	HTS002	1	2.849654	0.21408	0.128675	1.579261	4.16441	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000022
BRD-A98990573-003-01-3	ACH-000192	MFE280_ENDOMETRIUM	HTS002	1	5.776495	0.049361	0.026225	1.556052	61,649,147,560,466,696	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000192
BRD-A98990573-003-01-3	null	null	HTS002	1	1.991773	-0.127225	0.15483	1.433521	0.010058	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	false	ACH-000409_FAILED_STR
BRD-A98990573-003-01-3	ACH-000959	SNUC4_LARGE_INTESTINE	HTS002	1	1.58126	-0.039906	-0.108018	1.260033	0.000385	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000959
BRD-A98990573-003-01-3	ACH-000637	KYSE520_OESOPHAGUS	HTS002	1	1.806132	-0.025868	-0.035974	1.388385	0.004652	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000637
BRD-A98990573-003-01-3	ACH-000155	SW1990_PANCREAS	HTS002	1	1.667241	-0.126309	-0.078549	1.219068	0.000228	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000155
BRD-A98990573-003-01-3	ACH-000605	TE6_OESOPHAGUS	HTS002	1	1.692918	-0.021163	-0.001809	1.372409	94.487722	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000605
BRD-A98990573-003-01-3	ACH-000775	NCIH727_LUNG	HTS002	1	2.004188	0.189041	0.000074	1.385659	1.126313	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000775
BRD-A98990573-003-01-3	ACH-000860	NCIH358_LUNG	HTS002	1	1.611675	-0.116383	-0.059631	1.400415	21.867509	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000860
BRD-A98990573-003-01-3	ACH-000994	HEC59_ENDOMETRIUM	HTS002	1	1.6132	0.005475	-0.023992	1.30062	97.074906	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000994
BRD-A98990573-003-01-3	ACH-000277	HCC1419_BREAST	HTS002	1	1.817855	0.148964	-0.06611	1.400429	0.104524	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000277
BRD-A98990573-003-01-3	ACH-000496	NCIH1792_LUNG	HTS002	1	2.006292	0.107423	-0.0509	1.477566	0.205818	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000496
BRD-A98990573-003-01-3	ACH-000866	NCIH1048_LUNG	HTS002	1	1.3709	-0.273824	-0.014405	1.19876	0.142358	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000866
BRD-A98990573-003-01-3	ACH-000869	NCIH1568_LUNG	HTS002	1	1.999161	0.186577	0.010162	1.442858	0.28791	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000869
BRD-A98990573-003-01-3	ACH-000117	EFM192A_BREAST	HTS002	1	1.85007	0.094906	-0.05222	1.48222	0.004288	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000117
BRD-A98990573-003-01-3	ACH-000678	MKN7_STOMACH	HTS002	1	1.542258	-0.042947	-0.105344	1.220461	0.000011	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000678
BRD-A98990573-003-01-3	ACH-000493	SNU423_LIVER	HTS002	1	1.431697	-0.012029	0.001154	1.234876	188,865.714916	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000493
BRD-A98990573-003-01-3	ACH-000097	ZR751_BREAST	HTS002	1	1.688471	1.484038	0.091142	1.107607	2.365127	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000097
BRD-A98990573-003-01-3	ACH-000313	KMRC3_KIDNEY	HTS002	1	1.407259	0.026586	-0.000548	1.204152	0.064402	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000313
BRD-A98990573-003-01-3	ACH-000169	RD_SOFT_TISSUE	HTS002	1	1.723997	-1.182939	0.351372	1.489127	0.438146	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000169
BRD-A98990573-003-01-3	null	null	HTS002	1	1.402584	-0.29955	0.024625	1.257358	0.723461	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	false	ACH-000010_FAILED_STR
BRD-A98990573-003-01-3	ACH-000841	NCIH2087_LUNG	HTS002	1	2.302524	-0.03314	-0.024387	1.661319	0.198809	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000841
BRD-A98990573-003-01-3	ACH-000414	NCIH1944_LUNG	HTS002	1	1.430148	0.015985	-0.030223	1.226841	0.000082	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000414
BRD-A98990573-003-01-3	ACH-000026	253JBV_URINARY_TRACT	HTS002	1	1.590001	-0.120299	-0.03823	1.265009	0.01366	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000026
BRD-A98990573-003-01-3	ACH-000649	786O_KIDNEY	HTS002	1	1.373033	0.294751	0.092384	1.188715	0.071175	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000649
BRD-A98990573-003-01-3	ACH-000966	IGROV1_OVARY	HTS002	1	1.947296	-0.238581	-0.02683	1.186921	0.000126	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000966
BRD-A98990573-003-01-3	ACH-000958	SW48_LARGE_INTESTINE	HTS002	1	3.870752	1.502423	0.17529	1.146091	9.385151	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000958
BRD-A98990573-003-01-3	ACH-000270	HPAC_PANCREAS	HTS002	1	2.011599	-0.021576	-0.008895	1.586784	251,361.840362	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000270
BRD-A98990573-003-01-3	ACH-000535	BXPC3_PANCREAS	HTS002	1	1.964786	-0.014508	0.001158	1.67857	5,536,578,342,584,630,000,000,000	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000535

BRD-A98990573-003-01-3

ACH-000650

IGR37_SKIN

HTS002

1

1.820349

-0.024736

-0.297873

1.420808

0.637424

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000650

BRD-A98990573-003-01-3

ACH-000748

SJSA1_BONE

HTS002

1

1.629373

-0.022834

-0.003305

1.367757

237,882.528641

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000748

BRD-A98990573-003-01-3

ACH-000788

A2058_SKIN

HTS002

1

1.556304

-0.241323

0.299702

1.227845

0.014518

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000788

BRD-A98990573-003-01-3

ACH-000545

VMCUB1_URINARY_TRACT

HTS002

1

0.730028

-2.439885

-0.209177

0.904544

0.018865

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000545

BRD-A98990573-003-01-3

ACH-000762

YD38_UPPER_AERODIGESTIVE_TRACT

HTS002

1

2.018194

-0.125205

-0.058569

1.619976

2.981759

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000762

BRD-A98990573-003-01-3

ACH-000211

DAOY_CENTRAL_NERVOUS_SYSTEM

HTS002

1

1.830988

-0.144544

0.048558

1.327476

0.003536

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000211

BRD-A98990573-003-01-3

ACH-000936

EFO27_OVARY

HTS002

1

1.838278

-0.062131

0.015137

1.364389

0.001102

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000936

BRD-A98990573-003-01-3

ACH-000882

IGR1_SKIN

HTS002

1

1.783593

0.09278

0.082606

1.267679

103.296555

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000882

BRD-A98990573-003-01-3

ACH-000471

LI7_LIVER

HTS002

1

1.533157

0.505352

0.058605

1.34906

0.012633

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000471

BRD-A98990573-003-01-3

ACH-000670

SBC5_LUNG

HTS002

1

1.368531

-0.258409

0.075831

1.147542

0.013438

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000670

BRD-A98990573-003-01-3

ACH-000048

TOV112D_OVARY

HTS002

1

1.550195

0.063352

-0.071279

1.321229

0.000358

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000048

BRD-A98990573-003-01-3

ACH-000259

KELLY_AUTONOMIC_GANGLIA

HTS002

1

1.515884

-0.109124

-0.036485

1.227478

0.008442

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000259

BRD-A98990573-003-01-3

ACH-000599

PATU8902_PANCREAS

HTS002

1

1.697333

-0.0204

-0.053723

1.376231

185.683349

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000599

BRD-A98990573-003-01-3

ACH-000716

TT2609C02_THYROID

HTS002

1

1.638413

0.003429

-0.008691

1.317777

1.064217

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000716

BRD-A98990573-003-01-3

ACH-000347

QGP1_PANCREAS

HTS002

1

1.566898

-0.433016

0.009184

1.14365

0.002978

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000347

BRD-A98990573-003-01-3

ACH-000566

SW1710_URINARY_TRACT

HTS002

1

1.350184

0.069992

-0.053704

1.203651

0.000678

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000566

BRD-A98990573-003-01-3

ACH-001016

BECKER_CENTRAL_NERVOUS_SYSTEM

HTS002

1

1.361135

-0.310624

0.065313

1.243253

1.208025

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-001016

BRD-A98990573-003-01-3

ACH-000395

NCIH520_LUNG

HTS002

1

1.436174

-0.097299

-0.027539

1.256566

3.263453

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000395

BRD-A98990573-003-01-3

ACH-000407

SNU685_ENDOMETRIUM

HTS002

1

1.945127

0.090783

-0.01996

1.492706

0.030072

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000407

BRD-A98990573-003-01-3

ACH-000418

SW1353_BONE

HTS002

1

3.419838

-0.114436

-0.015998

2.132578

0.024805

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000418

BRD-A98990573-003-01-3

ACH-000008

A101D_SKIN

HTS002

1

1.501761

0.218633

0.006067

1.202753

0.542737

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000008

BRD-A98990573-003-01-3

ACH-000191

BHT101_THYROID

HTS002

1

1.609186

-0.123199

-0.075613

1.345817

0.760553

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000191

BRD-A98990573-003-01-3

ACH-000941

HEC1B_ENDOMETRIUM

HTS002

1

1.527177

-0.042788

-0.050364

1.254625

0.015838

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000941

BRD-A98990573-003-01-3

ACH-000532

SNU61_LARGE_INTESTINE

HTS002

1

2.091377

-0.042439

-0.004104

1.576969

1.178751

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000532

BRD-A98990573-003-01-3

ACH-000316

SNU886_LIVER

HTS002

1

1.593947

0.129343

0.071052

1.254468

0.779699

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000316

BRD-A98990573-003-01-3

ACH-000677

SW1573_LUNG

HTS002

1

1.67553

0.131864

-0.009404

1.256825

3.59763

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000677

BRD-A98990573-003-01-3

ACH-000210

CADOES1_BONE

HTS002

1

1.448094

-0.249945

0.021653

1.091691

0.000195

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000210

BRD-A98990573-003-01-3

ACH-000803

COLO668_LUNG

HTS002

1

1.765142

0.098226

-0.108707

1.511044

0.000056

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000803

BRD-A98990573-003-01-3

ACH-000007

LS513_LARGE_INTESTINE

HTS002

1

2.04869

0.11884

-0.052451

1.43607

1.475633

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000007

BRD-A98990573-003-01-3

ACH-000719

RMGI_OVARY

HTS002

1

1.231354

-0.054457

-0.083873

1.194003

1,242,980,391,363.15

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000719

BRD-A98990573-003-01-3

ACH-000484

VMRCRCW_KIDNEY

HTS002

1

1.545587

0.007846

-0.008949

1.271739

0.209228

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000484

BRD-A98990573-003-01-3

ACH-000433

CAKI1_KIDNEY

HTS002

1

1.830107

-0.045053

-0.094601

1.387762

0.004152

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000433

BRD-A98990573-003-01-3

ACH-000688

OV7_OVARY

HTS002

1

2.525953

0.029149

-0.019781

1.817195

0.000586

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000688

BRD-A98990573-003-01-3

ACH-000603

BEN_LUNG

HTS002

1

1.58366

0.013974

0.008093

1.261426

248,022.635199

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000603

BRD-A98990573-003-01-3

ACH-000351

MKN1_STOMACH

HTS002

1

1.70352

-0.260435

0.05367

1.304682

0.024315

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000351

BRD-A98990573-003-01-3

ACH-000627

LCLC103H_LUNG

HTS002

1

2.170173

0.142362

-0.004723

1.250698

987.354029

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000627

BRD-A98990573-003-01-3

ACH-000916

NCIH1573_LUNG

HTS002

1

2.311052

0.006035

0.004773

1.656346

0.051606

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000916

BRD-A98990573-003-01-3

ACH-000863

DBTRG05MG_CENTRAL_NERVOUS_SYSTEM

HTS002

1

1.635168

0.069947

-0.169209

1.394398

0.000063

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000863

BRD-A98990573-003-01-3

ACH-000066

HCC4006_LUNG

HTS002

1

1.322655

-0.017401

0.000458

1.173943

640.458479

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000066

BRD-A98990573-003-01-3

ACH-000015

NCIH1581_LUNG

HTS002

1

1.536849

0.165862

-0.24244

1.200193

2.112639

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000015

BRD-A98990573-003-01-3

null

HTS002

1

1.713302

-0.092802

-0.156442

1.371913

0.199668

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

false

ACH-000511_FAILED_STR

BRD-A98990573-003-01-3

ACH-000674

NUGC4_STOMACH

HTS002

1

1.763321

-0.468645

0.649527

1.333147

0.0365

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000674

BRD-A98990573-003-01-3

ACH-000892

NCIH1563_LUNG

HTS002

1

1.081033

-0.349447

0.004121

1.014616

0.00045

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000892

BRD-A98990573-003-01-3

ACH-000909

JHUEM2_ENDOMETRIUM

HTS002

1

1.668088

0.299063

0.020538

1.30189

0.166195

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000909

BRD-A98990573-003-01-3

ACH-000237

JHOM1_OVARY

HTS002

1

1.619702

-0.19998

-0.034923

1.323298

0.124729

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000237

BRD-A98990573-003-01-3

ACH-000811

SKOV3_OVARY

HTS002

1

1.755043

-0.048146

-0.048229

1.431482

31.690909

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000811

BRD-A98990573-003-01-3

ACH-000312

SKNBE2_AUTONOMIC_GANGLIA

HTS002

1

1.576632

-0.076188

-0.052859

1.291012

0.100139

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000312

BRD-A98990573-003-01-3

ACH-000901

HCC1359_LUNG

HTS002

1

1.907709

0.093215

-0.115198

1.278326

569.579826

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000901

BRD-A98990573-003-01-3

ACH-000289

SNU466_CENTRAL_NERVOUS_SYSTEM

HTS002

1

2.014481

-0.36223

-0.038471

1.080091

0.000029

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000289

BRD-A98990573-003-01-3

ACH-000733

NCIH1838_LUNG

HTS002

1

1.855177

0.043852

-0.012144

1.500318

0.00003

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000733

BRD-A98990573-003-01-3

ACH-000268

SNU245_BILIARY_TRACT

HTS002

1

3.019335

0.145389

-0.006777

1.601176

35.950204

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000268

BRD-A98990573-003-01-3

ACH-000758

MKN74_STOMACH

HTS002

1

1.753247

0.067618

-0.117205

1.201335

264,905.16381

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000758

BRD-A98990573-003-01-3

ACH-000693

KYSE180_OESOPHAGUS

HTS002

1

1.433797

-0.512194

0.110691

1.376238

11.132484

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000693

BRD-A98990573-003-01-3

ACH-000264

CALU6_LUNG

HTS002

1

1.490461

-0.034016

0.007249

1.271417

43.264337

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000264

BRD-A98990573-003-01-3

ACH-000027

GOS3_CENTRAL_NERVOUS_SYSTEM

HTS002

1

1.780976

0.002659

-0.008845

1.380583

15,123,858.959958

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000027

BRD-A98990573-003-01-3

ACH-000720

TCCSUP_URINARY_TRACT

HTS002

1

2.198203

-0.414899

0.305273

1.387095

0.007678

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000720

BRD-A98990573-003-01-3

ACH-000814

HS939T_SKIN

HTS002

1

1.089522

0.350289

-0.087846

1.073917

0.000398

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000814

BRD-A98990573-003-01-3

ACH-000885

TOV21G_OVARY

HTS002

1

1.446876

-0.015603

-0.097006

1.310256

5,392,312,553,618,920,000,000

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000885

BRD-A98990573-003-01-3

ACH-000663

OVTOKO_OVARY

HTS002

1

1.512865

0.023007

-0.026331

1.201196

14,546,468.52015

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000663

BRD-A98990573-003-01-3

ACH-000647

TE1_OESOPHAGUS

HTS002

1

1.140966

-0.112351

-0.167108

1.110303

8,887.776362

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000647

BRD-A98990573-003-01-3

ACH-000243

DANG_PANCREAS

HTS002

1

2.06798

0.023153

-0.05191

1.48485

228.312576

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000243

BRD-A98990573-003-01-3

ACH-000255

LMSU_STOMACH

HTS002

1

1.694342

-0.174073

-0.048759

1.36352

0.138591

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000255

BRD-A98990573-003-01-3

ACH-000335

MSTO211H_PLEURA

HTS002

1

1.611948

0.242362

0.046093

1.163893

7.613375

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000335

BRD-A98990573-003-01-3

ACH-000147

T47D_BREAST

HTS002

1

1.515829

0.438492

0.221054

1.282377

0.043484

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000147

BRD-A98990573-003-01-3

ACH-000090

PC3_PROSTATE

HTS002

1

1.394236

0.025992

-0.000826

1.204897

0.003728

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000090

BRD-A98990573-003-01-3

ACH-000171

VMRCRCZ_KIDNEY

HTS002

1

2.656364

0.187366

0.304236

1.728065

0.311903

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000171

BRD-A98990573-003-01-3

ACH-000614

RVH421_SKIN

HTS002

1

1.272173

-0.052696

-0.098616

1.214494

5,870,546,788.39555

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000614

BRD-A98990573-003-01-3

ACH-000132

JHOS2_OVARY

HTS002

1

2.230741

0.325283

0.221803

1.396745

1.183204

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000132

BRD-A98990573-003-01-3

ACH-000274

HS852T_SKIN

HTS002

1

1.47399

-0.479815

0.057247

1.142754

0.006838

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000274

BRD-A98990573-003-01-3

null

HTS002

1

1.750228

0.201317

-0.000113

1.29669

0.756598

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

false

ACH-000807_FAILED_STR

BRD-A98990573-003-01-3

ACH-000810

SKMEL30_SKIN

HTS002

1

2.472409

-0.199165

0.152451

1.618257

0.01363

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000810

BRD-A98990573-003-01-3

ACH-000022

PATU8988S_PANCREAS

HTS002

1

2.849654

0.21408

0.128675

1.579261

4.16441

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000022

BRD-A98990573-003-01-3

ACH-000192

MFE280_ENDOMETRIUM

HTS002

1

5.776495

0.049361

0.026225

1.556052

61,649,147,560,466,696

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000192

BRD-A98990573-003-01-3

null

HTS002

1

1.991773

-0.127225

0.15483

1.433521

0.010058

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

false

ACH-000409_FAILED_STR

BRD-A98990573-003-01-3

ACH-000959

SNUC4_LARGE_INTESTINE

HTS002

1

1.58126

-0.039906

-0.108018

1.260033

0.000385

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000959

BRD-A98990573-003-01-3

ACH-000637

KYSE520_OESOPHAGUS

HTS002

1

1.806132

-0.025868

-0.035974

1.388385

0.004652

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000637

BRD-A98990573-003-01-3

ACH-000155

SW1990_PANCREAS

HTS002

1

1.667241

-0.126309

-0.078549

1.219068

0.000228

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000155

BRD-A98990573-003-01-3

ACH-000605

TE6_OESOPHAGUS

HTS002

1

1.692918

-0.021163

-0.001809

1.372409

94.487722

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000605

BRD-A98990573-003-01-3

ACH-000775

NCIH727_LUNG

HTS002

1

2.004188

0.189041

0.000074

1.385659

1.126313

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000775

BRD-A98990573-003-01-3

ACH-000860

NCIH358_LUNG

HTS002

1

1.611675

-0.116383

-0.059631

1.400415

21.867509

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000860

BRD-A98990573-003-01-3

ACH-000994

HEC59_ENDOMETRIUM

HTS002

1

1.6132

0.005475

-0.023992

1.30062

97.074906

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000994

BRD-A98990573-003-01-3

ACH-000277

HCC1419_BREAST

HTS002

1

1.817855

0.148964

-0.06611

1.400429

0.104524

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000277

BRD-A98990573-003-01-3

ACH-000496

NCIH1792_LUNG

HTS002

1

2.006292

0.107423

-0.0509

1.477566

0.205818

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000496

BRD-A98990573-003-01-3

ACH-000866

NCIH1048_LUNG

HTS002

1

1.3709

-0.273824

-0.014405

1.19876

0.142358

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000866

BRD-A98990573-003-01-3

ACH-000869

NCIH1568_LUNG

HTS002

1

1.999161

0.186577

0.010162

1.442858

0.28791

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000869

BRD-A98990573-003-01-3

ACH-000117

EFM192A_BREAST

HTS002

1

1.85007

0.094906

-0.05222

1.48222

0.004288

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000117

BRD-A98990573-003-01-3

ACH-000678

MKN7_STOMACH

HTS002

1

1.542258

-0.042947

-0.105344

1.220461

0.000011

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000678

BRD-A98990573-003-01-3

ACH-000493

SNU423_LIVER

HTS002

1

1.431697

-0.012029

0.001154

1.234876

188,865.714916

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000493

BRD-A98990573-003-01-3

ACH-000097

ZR751_BREAST

HTS002

1

1.688471

1.484038

0.091142

1.107607

2.365127

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000097

BRD-A98990573-003-01-3

ACH-000313

KMRC3_KIDNEY

HTS002

1

1.407259

0.026586

-0.000548

1.204152

0.064402

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000313

BRD-A98990573-003-01-3

ACH-000169

RD_SOFT_TISSUE

HTS002

1

1.723997

-1.182939

0.351372

1.489127

0.438146

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000169

BRD-A98990573-003-01-3

null

HTS002

1

1.402584

-0.29955

0.024625

1.257358

0.723461

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

false

ACH-000010_FAILED_STR

BRD-A98990573-003-01-3

ACH-000841

NCIH2087_LUNG

HTS002

1

2.302524

-0.03314

-0.024387

1.661319

0.198809

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000841

BRD-A98990573-003-01-3

ACH-000414

NCIH1944_LUNG

HTS002

1

1.430148

0.015985

-0.030223

1.226841

0.000082

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000414

BRD-A98990573-003-01-3

ACH-000026

253JBV_URINARY_TRACT

HTS002

1

1.590001

-0.120299

-0.03823

1.265009

0.01366

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000026

BRD-A98990573-003-01-3

ACH-000649

786O_KIDNEY

HTS002

1

1.373033

0.294751

0.092384

1.188715

0.071175

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000649

BRD-A98990573-003-01-3

ACH-000966

IGROV1_OVARY

HTS002

1

1.947296

-0.238581

-0.02683

1.186921

0.000126

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000966

BRD-A98990573-003-01-3

ACH-000958

SW48_LARGE_INTESTINE

HTS002

1

3.870752

1.502423

0.17529

1.146091

9.385151

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000958

BRD-A98990573-003-01-3

ACH-000270

HPAC_PANCREAS

HTS002

1

2.011599

-0.021576

-0.008895

1.586784

251,361.840362

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000270

BRD-A98990573-003-01-3

ACH-000535

BXPC3_PANCREAS

HTS002

1

1.964786

-0.014508

0.001158

1.67857

5,536,578,342,584,630,000,000,000

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000535