donb-hf/secondary-screen-dose-response-curve-parameters

broad_id string	depmap_id string	ccle_name string	screen_id string	upper_limit int64	lower_limit float64	slope float64	r2 float64	auc float64	ec50 float64	ic50 float64	name string	moa string	target string	disease.area string	indication string	smiles string	phase string	passed_str_profiling bool	row_name string
BRD-A98990573-003-01-3	ACH-000911	NUGC3_STOMACH	HTS002	1	2.270044	-0.052399	-0.016824	1.641636	0.116516	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000911
BRD-A98990573-003-01-3	ACH-000401	COLO800_SKIN	HTS002	1	1.673051	0.158242	-0.11513	1.317817	0.163344	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000401
BRD-A98990573-003-01-3	ACH-000276	HCC38_BREAST	HTS002	1	1.511059	-0.041487	-0.002974	1.417695	418,292,667,506,538	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000276
BRD-A98990573-003-01-3	ACH-000724	HT1376_URINARY_TRACT	HTS002	1	1.95093	0.3638	-0.048066	1.258709	2.1591	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000724
BRD-A98990573-003-01-3	ACH-000092	NCIH2452_PLEURA	HTS002	1	1.56619	-0.062879	0.000222	1.26102	0.006384	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000092
BRD-A98990573-003-01-3	ACH-000890	SW1271_LUNG	HTS002	1	1.605061	-0.024014	-0.022943	1.306457	0.230563	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000890
BRD-A98990573-003-01-3	null	null	HTS002	1	1.310172	-0.414347	-0.473982	1.198186	0.472608	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	false	ACH-000539_FAILED_STR
BRD-A98990573-003-01-3	ACH-000800	NCIH446_LUNG	HTS002	1	1.655441	-0.201679	0.058435	1.264045	0.009539	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000800
BRD-A98990573-003-01-3	ACH-000899	WM88_SKIN	HTS002	1	1.912961	-0.024736	-0.012386	1.482235	7.558243	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000899
BRD-A98990573-003-01-3	ACH-000622	KNS42_CENTRAL_NERVOUS_SYSTEM	HTS002	1	1.757262	0.078995	0.066373	1.352979	0.444598	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000622
BRD-A98990573-003-01-3	ACH-000403	NCIH747_LARGE_INTESTINE	HTS002	1	1.74041	-2.943309	0.40992	1.322974	0.042067	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000403
BRD-A98990573-003-01-3	ACH-000141	SNU308_BILIARY_TRACT	HTS002	1	1.903993	-2.161633	0.042911	1.608473	0.419271	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000141
BRD-A98990573-003-01-3	ACH-000848	JHH7_LIVER	HTS002	1	1.598904	-0.000643	-0.026058	1.299293	0.015059	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000848
BRD-A98990573-003-01-3	ACH-000785	NCIH2126_LUNG	HTS002	1	1.750434	-0.146394	0.032477	1.348208	0.028	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000785
BRD-A98990573-003-01-3	ACH-000544	OE21_OESOPHAGUS	HTS002	1	1.995005	0.072858	0.012931	1.439623	1.997497	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000544
BRD-A98990573-003-01-3	ACH-000982	GP2D_LARGE_INTESTINE	HTS002	1	1.982194	0.205401	0.052662	1.380065	0.877931	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000982
BRD-A98990573-003-01-3	ACH-000021	NCIH1693_LUNG	HTS002	1	1.94151	3.598905	0.536436	1.294612	0.480006	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000021
BRD-A98990573-003-01-3	ACH-000823	KYSE140_OESOPHAGUS	HTS002	1	1.73979	-0.013058	-0.009853	1.379835	4.801312	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000823
BRD-A98990573-003-01-3	ACH-000915	IPC298_SKIN	HTS002	1	1.70709	-0.198826	0.082373	1.227577	0.0014	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000915
BRD-A98990573-003-01-3	ACH-000984	HEC6_ENDOMETRIUM	HTS002	1	1.938033	0.096819	-0.06593	1.543229	0.002724	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000984
BRD-A98990573-003-01-3	ACH-000579	UACC257_SKIN	HTS002	1	1.707654	0.014671	-0.014332	1.372521	0.000058	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000579
BRD-A98990573-003-01-3	ACH-001306	8305C_THYROID	HTS002	1	1.983018	-0.045534	-0.04948	1.526152	1.757915	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-001306
BRD-A98990573-003-01-3	ACH-000318	TE10_OESOPHAGUS	HTS002	1	1.509291	-0.056303	-0.028275	1.397143	501,194,193.878263	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000318
BRD-A98990573-003-01-3	ACH-000840	HCC366_LUNG	HTS002	1	1.760301	0.084273	-0.12012	1.354139	0.406368	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000840
BRD-A98990573-003-01-3	ACH-000726	TE14_OESOPHAGUS	HTS002	1	2.195044	0.201883	0.066219	1.50514	0.412763	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000726
BRD-A98990573-003-01-3	ACH-000919	IM95_STOMACH	HTS002	1	2.014472	0.154848	0.108424	1.486598	0.135449	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000919
BRD-A98990573-003-01-3	ACH-000188	SCC25_UPPER_AERODIGESTIVE_TRACT	HTS002	1	2.673356	0.422669	0.15005	1.217524	21.416133	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000188
BRD-A98990573-003-01-3	ACH-000618	SNU1041_UPPER_AERODIGESTIVE_TRACT	HTS002	1	1.487293	-0.184499	0.001836	1.227142	0.035676	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000618
BRD-A98990573-003-01-3	ACH-000822	SKMEL24_SKIN	HTS002	1	1.876088	-0.156416	0.028237	1.323975	0.002208	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000822
BRD-A98990573-003-01-3	ACH-000292	NCIH841_LUNG	HTS002	1	1.235913	-0.146241	-0.081582	1.16976	63.075693	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000292
BRD-A98990573-003-01-3	ACH-000827	WM793_SKIN	HTS002	1	1.387481	0.004993	-0.178442	1.191823	4.116085	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000827
BRD-A98990573-003-01-3	ACH-000411	769P_KIDNEY	HTS002	1	1.452495	-0.025446	-0.107236	1.208085	0.000139	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000411
BRD-A98990573-003-01-3	ACH-000139	PANC0327_PANCREAS	HTS002	1	1.224094	1.652479	-0.146302	1.135705	0.028017	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000139
BRD-A98990573-003-01-3	ACH-000569	ISTMES1_PLEURA	HTS002	1	-0.198909	0.995776	0.032077	0.979333	45.527491	32.52418	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000569
BRD-A98990573-003-01-3	ACH-000741	UBLC1_URINARY_TRACT	HTS002	1	1.650581	0.227921	0.042193	1.268899	0.422796	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000741
BRD-A98990573-003-01-3	ACH-000278	COV362_OVARY	HTS002	1	1.888812	-0.412657	0.102878	1.220877	0.002514	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000278
BRD-A98990573-003-01-3	ACH-000425	UACC62_SKIN	HTS002	1	1.735781	0.225036	0.22096	1.325224	0.243251	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000425
BRD-A98990573-003-01-3	ACH-000013	ONCODG1_OVARY	HTS002	1	3.594364	0.184307	-0.088925	1.389671	1,555.897984	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000013
BRD-A98990573-003-01-3	ACH-000231	KALS1_CENTRAL_NERVOUS_SYSTEM	HTS002	1	1.466078	0.181782	0.001656	1.211395	0.232406	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000231
BRD-A98990573-003-01-3	ACH-000730	SKMEL5_SKIN	HTS002	1	2.107826	-0.166532	0.073543	1.560999	0.091855	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000730
BRD-A98990573-003-01-3	ACH-000477	MALME3M_SKIN	HTS002	1	1.390129	-2.510109	0.144531	1.237904	0.226764	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000477
BRD-A98990573-003-01-3	ACH-000495	TUHR4TKB_KIDNEY	HTS002	1	2.560621	0.267535	0.149534	1.378815	9.256313	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000495
BRD-A98990573-003-01-3	ACH-000434	NCIH1915_LUNG	HTS002	1	1.663688	-0.407771	0.072124	1.220872	0.008605	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000434
BRD-A98990573-003-01-3	ACH-000744	NCIH1623_LUNG	HTS002	1	1.714907	-0.171481	-0.014329	1.377898	0.158246	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000744
BRD-A98990573-003-01-3	ACH-000107	CAPAN2_PANCREAS	HTS002	1	1.96487	-0.117449	0.102504	1.405407	0.004678	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000107
BRD-A98990573-003-01-3	ACH-000516	CAL78_BONE	HTS002	1	1.885008	0.04314	-0.00817	1.494382	0.000326	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000516
BRD-A98990573-003-01-3	ACH-000182	SNU869_BILIARY_TRACT	HTS002	1	1.29284	-0.129235	-0.091234	1.17449	1.735201	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000182
BRD-A98990573-003-01-3	ACH-000898	SNU719_STOMACH	HTS002	1	1.555408	-0.603122	-0.012647	1.440883	2.398775	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000898
BRD-A98990573-003-01-3	ACH-000040	U118MG_CENTRAL_NERVOUS_SYSTEM	HTS002	1	1.692987	-0.03653	0.000551	1.354575	0.281146	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000040
BRD-A98990573-003-01-3	ACH-000808	HUH28_BILIARY_TRACT	HTS002	1	1.96673	0.055543	-0.049106	1.439097	2.175937	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000808
BRD-A98990573-003-01-3	ACH-000715	SNU1214_UPPER_AERODIGESTIVE_TRACT	HTS002	1	1.946718	-0.074888	-0.023483	1.516402	0.91612	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000715
BRD-A98990573-003-01-3	ACH-000186	NCIH2444_LUNG	HTS002	1	2.465083	0.096945	-0.032348	1.790866	0.014615	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000186
BRD-A98990573-003-01-3	ACH-000542	HEYA8_OVARY	HTS002	1	1.53687	-1.293217	0.137103	1.42571	1.423436	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000542
BRD-A98990573-003-01-3	ACH-000943	RKO_LARGE_INTESTINE	HTS002	1	1.048673	0.425935	-0.138728	1.029004	0.023273	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000943
BRD-A98990573-003-01-3	ACH-000174	CAL62_THYROID	HTS002	1	1.671691	-0.377879	0.674005	1.399394	0.280778	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000174
BRD-A98990573-003-01-3	ACH-000393	HLF_LIVER	HTS002	1	1.82929	0.044906	-0.015329	1.466831	0.000273	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000393
BRD-A98990573-003-01-3	ACH-000018	T24_URINARY_TRACT	HTS002	1	1.590383	0.06853	0.000836	1.301301	0.042463	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000018
BRD-A98990573-003-01-3	ACH-000906	ES2_OVARY	HTS002	1	1.454967	0.244723	0.040806	1.236911	0.053544	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000906
BRD-A98990573-003-01-3	ACH-000784	KYSE70_OESOPHAGUS	HTS002	1	1.843527	-0.342202	0.444436	1.369397	0.032119	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000784
BRD-A98990573-003-01-3	ACH-000265	KP4_PANCREAS	HTS002	1	2.215889	-0.001804	-0.001816	1.611836	94.511103	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000265
BRD-A98990573-003-01-3	ACH-000880	AGS_STOMACH	HTS002	1	2.009145	0.037085	-0.058148	1.462353	7.28468	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000880
BRD-A98990573-003-01-3	ACH-000961	ISHIKAWAHERAKLIO02ER_ENDOMETRIUM	HTS002	1	1.553639	0.195462	-0.015378	1.340467	0.005985	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000961
BRD-A98990573-003-01-3	ACH-000847	HGC27_STOMACH	HTS002	1	1.819924	0.03141	-0.108798	1.409287	0.086779	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000847
BRD-A98990573-003-01-3	ACH-000896	647V_URINARY_TRACT	HTS002	1	1.842775	-0.095949	-0.05772	1.459409	0.532748	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000896
BRD-A98990573-003-01-3	ACH-000685	L33_PANCREAS	HTS002	1	3.463387	0.179422	-0.030533	1.316717	5,593.284311	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000685
BRD-A98990573-003-01-3	ACH-000376	SF295_CENTRAL_NERVOUS_SYSTEM	HTS002	1	1.524087	0.014057	-0.312739	1.267697	0.003623	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000376
BRD-A98990573-003-01-3	ACH-000428	UO31_KIDNEY	HTS002	1	1.825075	0.0408	0.030597	1.397175	0.488108	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000428
BRD-A98990573-003-01-3	ACH-000749	DMS273_LUNG	HTS002	1	2.069051	-0.187511	0.325075	1.447982	0.012165	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000749
BRD-A98990573-003-01-3	ACH-000572	G361_SKIN	HTS002	1	1.134454	-0.042348	-0.115891	1.076825	71.037098	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000572
BRD-A98990573-003-01-3	ACH-000704	OAW42_OVARY	HTS002	1	1.583759	3.47639	0.422726	1.32484	0.045168	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000704
BRD-A98990573-003-01-3	ACH-000457	CAL54_KIDNEY	HTS002	1	1.496349	-0.1478	0.079759	1.287633	0.749659	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000457
BRD-A98990573-003-01-3	ACH-000601	MIAPACA2_PANCREAS	HTS002	1	1.490945	-0.125609	0.000801	1.216776	0.011371	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000601
BRD-A98990573-003-01-3	ACH-000651	SW620_LARGE_INTESTINE	HTS002	1	1.592819	-0.155297	-0.135345	1.216139	0.001855	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000651
BRD-A98990573-003-01-3	ACH-000361	SKHEP1_LIVER	HTS002	1	1.347115	-0.027104	-0.015181	1.248699	58,486,196,883,800.6	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000361
BRD-A98990573-003-01-3	ACH-000842	SW480_LARGE_INTESTINE	HTS002	1	1.181985	-0.09898	-0.075592	1.113899	15.588619	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000842
BRD-A98990573-003-01-3	ACH-000570	YKG1_CENTRAL_NERVOUS_SYSTEM	HTS002	1	2.032039	-4.762248	0.484125	1.458292	0.0454	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000570
BRD-A98990573-003-01-3	ACH-000396	J82_URINARY_TRACT	HTS002	1	1.624366	-0.132094	-0.095209	1.455414	180.017273	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000396
BRD-A98990573-003-01-3	ACH-000777	KYSE30_OESOPHAGUS	HTS002	1	1.404059	-0.111447	-0.050976	1.290885	451.350279	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000777
BRD-A98990573-003-01-3	ACH-000096	G401_SOFT_TISSUE	HTS002	1	1.828552	0.123746	0.034182	1.337476	1.770479	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000096
BRD-A98990573-003-01-3	ACH-000955	SNU407_LARGE_INTESTINE	HTS002	1	1.720502	0.097149	-0.002418	1.455078	0.000275	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000955
BRD-A98990573-003-01-3	ACH-000940	AN3CA_ENDOMETRIUM	HTS002	1	1.739941	-0.214155	0.02006	1.444546	0.622171	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000940
BRD-A98990573-003-01-3	ACH-001318	PLCPRF5_LIVER	HTS002	1	1.56191	-0.01409	-0.003417	1.410518	448,085,732,351,944,000,000,000,000,000	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-001318
BRD-A98990573-003-01-3	ACH-000332	YAPC_PANCREAS	HTS002	1	1.754922	0.094943	0.042832	1.255	105.781297	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000332
BRD-A98990573-003-01-3	ACH-000178	HS766T_PANCREAS	HTS002	1	1.69837	-0.011992	-0.094062	1.512115	339,457,286,375,868,000,000,000,000,000,000,000	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000178
BRD-A98990573-003-01-3	ACH-000421	SW837_LARGE_INTESTINE	HTS002	1	3.418263	0.166093	-0.056108	1.393973	2,292.151763	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000421
BRD-A98990573-003-01-3	ACH-000524	KURAMOCHI_OVARY	HTS002	1	1.758993	0.240228	0.07273	1.209049	6.614343	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000524
BRD-A98990573-003-01-3	ACH-000469	YH13_CENTRAL_NERVOUS_SYSTEM	HTS002	1	1.016227	-0.030939	-0.099396	1.009055	147.979395	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000469
BRD-A98990573-003-01-3	ACH-000153	NCIH2052_PLEURA	HTS002	1	2.061479	-0.006107	-0.03436	1.574251	38,040,123,810.9087	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000153
BRD-A98990573-003-01-3	ACH-000805	COLO679_SKIN	HTS002	1	1.519939	-0.131283	0.127811	1.277134	0.221282	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000805
BRD-A98990573-003-01-3	ACH-000429	A704_KIDNEY	HTS002	1	2.095231	-0.396452	0.09883	1.306056	0.003773	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000429
BRD-A98990573-003-01-3	ACH-000108	KP3_PANCREAS	HTS002	1	1.638366	-0.027491	0.012007	1.32417	0.243912	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000108
BRD-A98990573-003-01-3	ACH-000939	SKUT1_SOFT_TISSUE	HTS002	1	1.720309	0.0142	0.003259	1.346675	15.275513	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000939
BRD-A98990573-003-01-3	ACH-000323	42MGBA_CENTRAL_NERVOUS_SYSTEM	HTS002	1	1.497019	-0.065405	0.000728	1.254532	0.164953	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000323
BRD-A98990573-003-01-3	ACH-000219	A375_SKIN	HTS002	1	1.536055	-0.451096	0.041756	1.252163	0.054508	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000219
BRD-A98990573-003-01-3	ACH-000903	FTC133_THYROID	HTS002	1	1.708751	0.146686	0.002322	1.2888	1.114674	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000903
BRD-A98990573-003-01-3	ACH-000054	HT1080_SOFT_TISSUE	HTS002	1	1.466219	1.280988	0.135519	1.288592	0.024457	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000054
BRD-A98990573-003-01-3	ACH-000302	SNU1077_ENDOMETRIUM	HTS002	1	2.840171	0.201243	0.196547	1.793312	0.344977	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000302
BRD-A98990573-003-01-3	ACH-000324	JHOC5_OVARY	HTS002	1	1.237816	0.016142	-0.115305	1.122172	0.002597	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000324
BRD-A98990573-003-01-3	ACH-000164	PANC1_PANCREAS	HTS002	1	1.984436	-0.118915	0.115857	1.43324	0.009755	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000164
BRD-A98990573-003-01-3	ACH-000549	SNU1076_UPPER_AERODIGESTIVE_TRACT	HTS002	1	1.460061	-0.078816	-0.042646	1.257488	1.700432	null	epinastine	histamine receptor antagonist	ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7	ophthalmology	conjunctivitis	NC1=NCC2N1c1ccccc1Cc1ccccc21	Launched	true	ACH-000549

BRD-A98990573-003-01-3

ACH-000911

NUGC3_STOMACH

HTS002

1

2.270044

-0.052399

-0.016824

1.641636

0.116516

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000911

BRD-A98990573-003-01-3

ACH-000401

COLO800_SKIN

HTS002

1

1.673051

0.158242

-0.11513

1.317817

0.163344

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000401

BRD-A98990573-003-01-3

ACH-000276

HCC38_BREAST

HTS002

1

1.511059

-0.041487

-0.002974

1.417695

418,292,667,506,538

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000276

BRD-A98990573-003-01-3

ACH-000724

HT1376_URINARY_TRACT

HTS002

1

1.95093

0.3638

-0.048066

1.258709

2.1591

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000724

BRD-A98990573-003-01-3

ACH-000092

NCIH2452_PLEURA

HTS002

1

1.56619

-0.062879

0.000222

1.26102

0.006384

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000092

BRD-A98990573-003-01-3

ACH-000890

SW1271_LUNG

HTS002

1

1.605061

-0.024014

-0.022943

1.306457

0.230563

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000890

BRD-A98990573-003-01-3

null

HTS002

1

1.310172

-0.414347

-0.473982

1.198186

0.472608

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

false

ACH-000539_FAILED_STR

BRD-A98990573-003-01-3

ACH-000800

NCIH446_LUNG

HTS002

1

1.655441

-0.201679

0.058435

1.264045

0.009539

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000800

BRD-A98990573-003-01-3

ACH-000899

WM88_SKIN

HTS002

1

1.912961

-0.024736

-0.012386

1.482235

7.558243

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000899

BRD-A98990573-003-01-3

ACH-000622

KNS42_CENTRAL_NERVOUS_SYSTEM

HTS002

1

1.757262

0.078995

0.066373

1.352979

0.444598

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000622

BRD-A98990573-003-01-3

ACH-000403

NCIH747_LARGE_INTESTINE

HTS002

1

1.74041

-2.943309

0.40992

1.322974

0.042067

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000403

BRD-A98990573-003-01-3

ACH-000141

SNU308_BILIARY_TRACT

HTS002

1

1.903993

-2.161633

0.042911

1.608473

0.419271

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000141

BRD-A98990573-003-01-3

ACH-000848

JHH7_LIVER

HTS002

1

1.598904

-0.000643

-0.026058

1.299293

0.015059

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000848

BRD-A98990573-003-01-3

ACH-000785

NCIH2126_LUNG

HTS002

1

1.750434

-0.146394

0.032477

1.348208

0.028

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000785

BRD-A98990573-003-01-3

ACH-000544

OE21_OESOPHAGUS

HTS002

1

1.995005

0.072858

0.012931

1.439623

1.997497

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000544

BRD-A98990573-003-01-3

ACH-000982

GP2D_LARGE_INTESTINE

HTS002

1

1.982194

0.205401

0.052662

1.380065

0.877931

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000982

BRD-A98990573-003-01-3

ACH-000021

NCIH1693_LUNG

HTS002

1

1.94151

3.598905

0.536436

1.294612

0.480006

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000021

BRD-A98990573-003-01-3

ACH-000823

KYSE140_OESOPHAGUS

HTS002

1

1.73979

-0.013058

-0.009853

1.379835

4.801312

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000823

BRD-A98990573-003-01-3

ACH-000915

IPC298_SKIN

HTS002

1

1.70709

-0.198826

0.082373

1.227577

0.0014

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000915

BRD-A98990573-003-01-3

ACH-000984

HEC6_ENDOMETRIUM

HTS002

1

1.938033

0.096819

-0.06593

1.543229

0.002724

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000984

BRD-A98990573-003-01-3

ACH-000579

UACC257_SKIN

HTS002

1

1.707654

0.014671

-0.014332

1.372521

0.000058

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000579

BRD-A98990573-003-01-3

ACH-001306

8305C_THYROID

HTS002

1

1.983018

-0.045534

-0.04948

1.526152

1.757915

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-001306

BRD-A98990573-003-01-3

ACH-000318

TE10_OESOPHAGUS

HTS002

1

1.509291

-0.056303

-0.028275

1.397143

501,194,193.878263

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000318

BRD-A98990573-003-01-3

ACH-000840

HCC366_LUNG

HTS002

1

1.760301

0.084273

-0.12012

1.354139

0.406368

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000840

BRD-A98990573-003-01-3

ACH-000726

TE14_OESOPHAGUS

HTS002

1

2.195044

0.201883

0.066219

1.50514

0.412763

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000726

BRD-A98990573-003-01-3

ACH-000919

IM95_STOMACH

HTS002

1

2.014472

0.154848

0.108424

1.486598

0.135449

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000919

BRD-A98990573-003-01-3

ACH-000188

SCC25_UPPER_AERODIGESTIVE_TRACT

HTS002

1

2.673356

0.422669

0.15005

1.217524

21.416133

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000188

BRD-A98990573-003-01-3

ACH-000618

SNU1041_UPPER_AERODIGESTIVE_TRACT

HTS002

1

1.487293

-0.184499

0.001836

1.227142

0.035676

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000618

BRD-A98990573-003-01-3

ACH-000822

SKMEL24_SKIN

HTS002

1

1.876088

-0.156416

0.028237

1.323975

0.002208

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000822

BRD-A98990573-003-01-3

ACH-000292

NCIH841_LUNG

HTS002

1

1.235913

-0.146241

-0.081582

1.16976

63.075693

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000292

BRD-A98990573-003-01-3

ACH-000827

WM793_SKIN

HTS002

1

1.387481

0.004993

-0.178442

1.191823

4.116085

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000827

BRD-A98990573-003-01-3

ACH-000411

769P_KIDNEY

HTS002

1

1.452495

-0.025446

-0.107236

1.208085

0.000139

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000411

BRD-A98990573-003-01-3

ACH-000139

PANC0327_PANCREAS

HTS002

1

1.224094

1.652479

-0.146302

1.135705

0.028017

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000139

BRD-A98990573-003-01-3

ACH-000569

ISTMES1_PLEURA

HTS002

1

-0.198909

0.995776

0.032077

0.979333

45.527491

32.52418

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000569

BRD-A98990573-003-01-3

ACH-000741

UBLC1_URINARY_TRACT

HTS002

1

1.650581

0.227921

0.042193

1.268899

0.422796

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000741

BRD-A98990573-003-01-3

ACH-000278

COV362_OVARY

HTS002

1

1.888812

-0.412657

0.102878

1.220877

0.002514

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000278

BRD-A98990573-003-01-3

ACH-000425

UACC62_SKIN

HTS002

1

1.735781

0.225036

0.22096

1.325224

0.243251

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000425

BRD-A98990573-003-01-3

ACH-000013

ONCODG1_OVARY

HTS002

1

3.594364

0.184307

-0.088925

1.389671

1,555.897984

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000013

BRD-A98990573-003-01-3

ACH-000231

KALS1_CENTRAL_NERVOUS_SYSTEM

HTS002

1

1.466078

0.181782

0.001656

1.211395

0.232406

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000231

BRD-A98990573-003-01-3

ACH-000730

SKMEL5_SKIN

HTS002

1

2.107826

-0.166532

0.073543

1.560999

0.091855

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000730

BRD-A98990573-003-01-3

ACH-000477

MALME3M_SKIN

HTS002

1

1.390129

-2.510109

0.144531

1.237904

0.226764

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000477

BRD-A98990573-003-01-3

ACH-000495

TUHR4TKB_KIDNEY

HTS002

1

2.560621

0.267535

0.149534

1.378815

9.256313

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000495

BRD-A98990573-003-01-3

ACH-000434

NCIH1915_LUNG

HTS002

1

1.663688

-0.407771

0.072124

1.220872

0.008605

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000434

BRD-A98990573-003-01-3

ACH-000744

NCIH1623_LUNG

HTS002

1

1.714907

-0.171481

-0.014329

1.377898

0.158246

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000744

BRD-A98990573-003-01-3

ACH-000107

CAPAN2_PANCREAS

HTS002

1

1.96487

-0.117449

0.102504

1.405407

0.004678

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000107

BRD-A98990573-003-01-3

ACH-000516

CAL78_BONE

HTS002

1

1.885008

0.04314

-0.00817

1.494382

0.000326

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000516

BRD-A98990573-003-01-3

ACH-000182

SNU869_BILIARY_TRACT

HTS002

1

1.29284

-0.129235

-0.091234

1.17449

1.735201

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000182

BRD-A98990573-003-01-3

ACH-000898

SNU719_STOMACH

HTS002

1

1.555408

-0.603122

-0.012647

1.440883

2.398775

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000898

BRD-A98990573-003-01-3

ACH-000040

U118MG_CENTRAL_NERVOUS_SYSTEM

HTS002

1

1.692987

-0.03653

0.000551

1.354575

0.281146

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000040

BRD-A98990573-003-01-3

ACH-000808

HUH28_BILIARY_TRACT

HTS002

1

1.96673

0.055543

-0.049106

1.439097

2.175937

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000808

BRD-A98990573-003-01-3

ACH-000715

SNU1214_UPPER_AERODIGESTIVE_TRACT

HTS002

1

1.946718

-0.074888

-0.023483

1.516402

0.91612

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000715

BRD-A98990573-003-01-3

ACH-000186

NCIH2444_LUNG

HTS002

1

2.465083

0.096945

-0.032348

1.790866

0.014615

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000186

BRD-A98990573-003-01-3

ACH-000542

HEYA8_OVARY

HTS002

1

1.53687

-1.293217

0.137103

1.42571

1.423436

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000542

BRD-A98990573-003-01-3

ACH-000943

RKO_LARGE_INTESTINE

HTS002

1

1.048673

0.425935

-0.138728

1.029004

0.023273

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000943

BRD-A98990573-003-01-3

ACH-000174

CAL62_THYROID

HTS002

1

1.671691

-0.377879

0.674005

1.399394

0.280778

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000174

BRD-A98990573-003-01-3

ACH-000393

HLF_LIVER

HTS002

1

1.82929

0.044906

-0.015329

1.466831

0.000273

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000393

BRD-A98990573-003-01-3

ACH-000018

T24_URINARY_TRACT

HTS002

1

1.590383

0.06853

0.000836

1.301301

0.042463

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000018

BRD-A98990573-003-01-3

ACH-000906

ES2_OVARY

HTS002

1

1.454967

0.244723

0.040806

1.236911

0.053544

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000906

BRD-A98990573-003-01-3

ACH-000784

KYSE70_OESOPHAGUS

HTS002

1

1.843527

-0.342202

0.444436

1.369397

0.032119

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000784

BRD-A98990573-003-01-3

ACH-000265

KP4_PANCREAS

HTS002

1

2.215889

-0.001804

-0.001816

1.611836

94.511103

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000265

BRD-A98990573-003-01-3

ACH-000880

AGS_STOMACH

HTS002

1

2.009145

0.037085

-0.058148

1.462353

7.28468

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000880

BRD-A98990573-003-01-3

ACH-000961

ISHIKAWAHERAKLIO02ER_ENDOMETRIUM

HTS002

1

1.553639

0.195462

-0.015378

1.340467

0.005985

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000961

BRD-A98990573-003-01-3

ACH-000847

HGC27_STOMACH

HTS002

1

1.819924

0.03141

-0.108798

1.409287

0.086779

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000847

BRD-A98990573-003-01-3

ACH-000896

647V_URINARY_TRACT

HTS002

1

1.842775

-0.095949

-0.05772

1.459409

0.532748

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000896

BRD-A98990573-003-01-3

ACH-000685

L33_PANCREAS

HTS002

1

3.463387

0.179422

-0.030533

1.316717

5,593.284311

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000685

BRD-A98990573-003-01-3

ACH-000376

SF295_CENTRAL_NERVOUS_SYSTEM

HTS002

1

1.524087

0.014057

-0.312739

1.267697

0.003623

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000376

BRD-A98990573-003-01-3

ACH-000428

UO31_KIDNEY

HTS002

1

1.825075

0.0408

0.030597

1.397175

0.488108

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000428

BRD-A98990573-003-01-3

ACH-000749

DMS273_LUNG

HTS002

1

2.069051

-0.187511

0.325075

1.447982

0.012165

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000749

BRD-A98990573-003-01-3

ACH-000572

G361_SKIN

HTS002

1

1.134454

-0.042348

-0.115891

1.076825

71.037098

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000572

BRD-A98990573-003-01-3

ACH-000704

OAW42_OVARY

HTS002

1

1.583759

3.47639

0.422726

1.32484

0.045168

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000704

BRD-A98990573-003-01-3

ACH-000457

CAL54_KIDNEY

HTS002

1

1.496349

-0.1478

0.079759

1.287633

0.749659

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000457

BRD-A98990573-003-01-3

ACH-000601

MIAPACA2_PANCREAS

HTS002

1

1.490945

-0.125609

0.000801

1.216776

0.011371

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000601

BRD-A98990573-003-01-3

ACH-000651

SW620_LARGE_INTESTINE

HTS002

1

1.592819

-0.155297

-0.135345

1.216139

0.001855

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000651

BRD-A98990573-003-01-3

ACH-000361

SKHEP1_LIVER

HTS002

1

1.347115

-0.027104

-0.015181

1.248699

58,486,196,883,800.6

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000361

BRD-A98990573-003-01-3

ACH-000842

SW480_LARGE_INTESTINE

HTS002

1

1.181985

-0.09898

-0.075592

1.113899

15.588619

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000842

BRD-A98990573-003-01-3

ACH-000570

YKG1_CENTRAL_NERVOUS_SYSTEM

HTS002

1

2.032039

-4.762248

0.484125

1.458292

0.0454

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000570

BRD-A98990573-003-01-3

ACH-000396

J82_URINARY_TRACT

HTS002

1

1.624366

-0.132094

-0.095209

1.455414

180.017273

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000396

BRD-A98990573-003-01-3

ACH-000777

KYSE30_OESOPHAGUS

HTS002

1

1.404059

-0.111447

-0.050976

1.290885

451.350279

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000777

BRD-A98990573-003-01-3

ACH-000096

G401_SOFT_TISSUE

HTS002

1

1.828552

0.123746

0.034182

1.337476

1.770479

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000096

BRD-A98990573-003-01-3

ACH-000955

SNU407_LARGE_INTESTINE

HTS002

1

1.720502

0.097149

-0.002418

1.455078

0.000275

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000955

BRD-A98990573-003-01-3

ACH-000940

AN3CA_ENDOMETRIUM

HTS002

1

1.739941

-0.214155

0.02006

1.444546

0.622171

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000940

BRD-A98990573-003-01-3

ACH-001318

PLCPRF5_LIVER

HTS002

1

1.56191

-0.01409

-0.003417

1.410518

448,085,732,351,944,000,000,000,000,000

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-001318

BRD-A98990573-003-01-3

ACH-000332

YAPC_PANCREAS

HTS002

1

1.754922

0.094943

0.042832

1.255

105.781297

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000332

BRD-A98990573-003-01-3

ACH-000178

HS766T_PANCREAS

HTS002

1

1.69837

-0.011992

-0.094062

1.512115

339,457,286,375,868,000,000,000,000,000,000,000

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000178

BRD-A98990573-003-01-3

ACH-000421

SW837_LARGE_INTESTINE

HTS002

1

3.418263

0.166093

-0.056108

1.393973

2,292.151763

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000421

BRD-A98990573-003-01-3

ACH-000524

KURAMOCHI_OVARY

HTS002

1

1.758993

0.240228

0.07273

1.209049

6.614343

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000524

BRD-A98990573-003-01-3

ACH-000469

YH13_CENTRAL_NERVOUS_SYSTEM

HTS002

1

1.016227

-0.030939

-0.099396

1.009055

147.979395

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000469

BRD-A98990573-003-01-3

ACH-000153

NCIH2052_PLEURA

HTS002

1

2.061479

-0.006107

-0.03436

1.574251

38,040,123,810.9087

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000153

BRD-A98990573-003-01-3

ACH-000805

COLO679_SKIN

HTS002

1

1.519939

-0.131283

0.127811

1.277134

0.221282

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000805

BRD-A98990573-003-01-3

ACH-000429

A704_KIDNEY

HTS002

1

2.095231

-0.396452

0.09883

1.306056

0.003773

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000429

BRD-A98990573-003-01-3

ACH-000108

KP3_PANCREAS

HTS002

1

1.638366

-0.027491

0.012007

1.32417

0.243912

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000108

BRD-A98990573-003-01-3

ACH-000939

SKUT1_SOFT_TISSUE

HTS002

1

1.720309

0.0142

0.003259

1.346675

15.275513

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000939

BRD-A98990573-003-01-3

ACH-000323

42MGBA_CENTRAL_NERVOUS_SYSTEM

HTS002

1

1.497019

-0.065405

0.000728

1.254532

0.164953

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000323

BRD-A98990573-003-01-3

ACH-000219

A375_SKIN

HTS002

1

1.536055

-0.451096

0.041756

1.252163

0.054508

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000219

BRD-A98990573-003-01-3

ACH-000903

FTC133_THYROID

HTS002

1

1.708751

0.146686

0.002322

1.2888

1.114674

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000903

BRD-A98990573-003-01-3

ACH-000054

HT1080_SOFT_TISSUE

HTS002

1

1.466219

1.280988

0.135519

1.288592

0.024457

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000054

BRD-A98990573-003-01-3

ACH-000302

SNU1077_ENDOMETRIUM

HTS002

1

2.840171

0.201243

0.196547

1.793312

0.344977

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000302

BRD-A98990573-003-01-3

ACH-000324

JHOC5_OVARY

HTS002

1

1.237816

0.016142

-0.115305

1.122172

0.002597

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000324

BRD-A98990573-003-01-3

ACH-000164

PANC1_PANCREAS

HTS002

1

1.984436

-0.118915

0.115857

1.43324

0.009755

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000164

BRD-A98990573-003-01-3

ACH-000549

SNU1076_UPPER_AERODIGESTIVE_TRACT

HTS002

1

1.460061

-0.078816

-0.042646

1.257488

1.700432

null

epinastine

histamine receptor antagonist

ADRA1A, ADRA2A, HRH1, HRH2, HTR2A, HTR7

ophthalmology

conjunctivitis

NC1=NCC2N1c1ccccc1Cc1ccccc21

Launched

true

ACH-000549