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DerAnaesthesist.90480169.eng.abstr
|
DerAnaesthesist.90480169.eng.abstr
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[
{
"id": "DerAnaesthesist.90480169.eng.abstr-passage-0",
"type": "abstract",
"text": [
"We report on a case of a lumbar epidural abscess with staphylococcus aureus following a catheter epidural anaesthesia in a previously healthy and not immunesuppressed 34-year-old female . The indication for the epidural anaesthesia was mobilization of the right knee following arthrotomy due to chronic synovitis . On postoperative day 7 the patient experienced lumbar pain , headache and meningism . Magnetic resonance imaging revealed an epidural abscess at the height of the 3rd and 4th lumbar vertebrae . A rightsided intralaminar fenestration with debridement and drainage of the abscess was carried out immediately after confirmation of the diagnosis ."
],
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{
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"epidural abscess"
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"staphylococcus aureus"
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"epidural anaesthesia"
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"id": "DerAnaesthesist.90480169.eng.abstr-s2-t1",
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"mobilization"
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"knee"
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"id": "DerAnaesthesist.90480169.eng.abstr-s2-t4",
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"synovitis"
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"id": "DerAnaesthesist.90480169.eng.abstr-s3-t5",
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"id": "DerAnaesthesist.90480169.eng.abstr-s5-t2",
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"Every form of active euthanasia is a punishable offence under § 216 of the Penal Code ; nor is there any ethical justification for it from a medical point of view . The many strands of the movement in favour of making \" death on demand \" exempt from punishment in Germany as it is in The Netherlands cannot change this ."
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81,
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}
]
},
{
"id": "DerAnaesthesist.90480207.eng.abstr-s1-t3",
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],
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14,
31
]
],
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}
]
},
{
"id": "DerAnaesthesist.90480207.eng.abstr-s2-t1",
"type": "umlsterm",
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"movement"
],
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189,
197
]
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{
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}
]
},
{
"id": "DerAnaesthesist.90480207.eng.abstr-s2-t2",
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"death"
],
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[
220,
225
]
],
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{
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}
]
},
{
"id": "DerAnaesthesist.90480207.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"punishment"
],
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[
250,
260
]
],
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{
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"db_id": "C0034119"
}
]
},
{
"id": "DerAnaesthesist.90480207.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"Germany"
],
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264,
271
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]
},
{
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"Netherlands"
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288,
299
]
],
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{
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"db_id": "C0027778"
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]
}
] |
[] |
[] |
[
{
"id": "DerAnaesthesist.90480207.eng.abstr-s1-r1-t2.1-t1.1",
"type": "isa",
"arg1_id": "DerAnaesthesist.90480207.eng.abstr-s2-t2",
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},
{
"id": "DerAnaesthesist.90480207.eng.abstr-s1-r2-t2.1-t3.1",
"type": "isa",
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},
{
"id": "DerAnaesthesist.90480207.eng.abstr-s2-r1-t5.1-t3.1",
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},
{
"id": "DerAnaesthesist.90480207.eng.abstr-s2-r2-t2.1-t1.1",
"type": "evaluation_of",
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},
{
"id": "DerAnaesthesist.90480207.eng.abstr-s2-r3-t4.1-t3.1",
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}
] |
DerAnaesthesist.90480218.eng.abstr
|
DerAnaesthesist.90480218.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480218.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Objectives : The cardiotoxic properties of bupivacain have been well documented under in-vitro , as well as under in-vivio conditions . A further mechanism of cardiovascular impairment by bupivacaine via the central nervous system gained investigational interest in animal studies . The aim of our study was to demonstrate the effect of a ventriculocisternal perfusion of bupivacain on systemic hemodynamic variabels and their reversability by wash-out with mock-CSF ."
],
"offsets": [
[
0,
468
]
]
}
] |
[
{
"id": "DerAnaesthesist.90480218.eng.abstr-s1-t1",
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"Objectives"
],
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[
0,
10
]
],
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{
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"db_id": "C0018017"
}
]
},
{
"id": "DerAnaesthesist.90480218.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"bupivacaine"
],
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188,
199
]
],
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{
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"db_id": "C0006400"
}
]
},
{
"id": "DerAnaesthesist.90480218.eng.abstr-s2-t2",
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"text": [
"nervous"
],
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[
216,
223
]
],
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{
"db_name": "UMLS",
"db_id": "C0027769"
}
]
},
{
"id": "DerAnaesthesist.90480218.eng.abstr-s2-t3",
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"text": [
"animal"
],
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[
266,
272
]
],
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{
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"db_id": "C0003043"
},
{
"db_name": "UMLS",
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}
]
},
{
"id": "DerAnaesthesist.90480218.eng.abstr-s2-t4",
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"text": [
"nervous system"
],
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[
216,
230
]
],
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{
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"db_id": "C0027763"
}
]
},
{
"id": "DerAnaesthesist.90480218.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"central nervous system"
],
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[
208,
230
]
],
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{
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"db_id": "C0007679"
}
]
},
{
"id": "DerAnaesthesist.90480218.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"aim"
],
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[
287,
290
]
],
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{
"db_name": "UMLS",
"db_id": "C0108800"
}
]
},
{
"id": "DerAnaesthesist.90480218.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"perfusion"
],
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[
359,
368
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{
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]
},
{
"id": "DerAnaesthesist.90480218.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"hemodynamic"
],
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[
395,
406
]
],
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{
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"db_id": "C0019010"
}
]
},
{
"id": "DerAnaesthesist.90480218.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"mock-CSF"
],
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[
458,
466
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0009392"
},
{
"db_name": "UMLS",
"db_id": "C0007806"
}
]
}
] |
[] |
[] |
[
{
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"type": "result_of",
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},
{
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},
{
"id": "DerAnaesthesist.90480218.eng.abstr-s2-r3-t2.1-t3.1",
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},
{
"id": "DerAnaesthesist.90480218.eng.abstr-s2-r4-t4.1-t2.1",
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},
{
"id": "DerAnaesthesist.90480218.eng.abstr-s2-r5-t1.1-t2.1",
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},
{
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},
{
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{
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},
{
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{
"id": "DerAnaesthesist.90480218.eng.abstr-s3-r6-t3.1-t1.1",
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{
"id": "DerAnaesthesist.90480218.eng.abstr-s3-r7-t1.1-t3.1",
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},
{
"id": "DerAnaesthesist.90480218.eng.abstr-s3-r8-t3.1-t4.1",
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},
{
"id": "DerAnaesthesist.90480218.eng.abstr-s3-r9-t1.1-t4.1",
"type": "interacts_with",
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"arg2_id": "DerAnaesthesist.90480218.eng.abstr-s3-t4",
"normalized": []
}
] |
DerAnaesthesist.90480224.eng.abstr
|
DerAnaesthesist.90480224.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480224.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Objective : The aim of this study was to compare low dose dopamine and dopexamine with respect to of liver-venous oxygen saturation , oxygen delivery and - demand , liver function tests and cardiocirculatory effects in the reperfusion period during a hemihepatectomy operation with occlusion of the liver hilus ."
],
"offsets": [
[
0,
312
]
]
}
] |
[
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-t1",
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0,
9
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{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-t2",
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19
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]
},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-t3",
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"text": [
"dopamine"
],
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[
58,
66
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0013030"
}
]
},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"dopexamine"
],
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[
71,
81
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],
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{
"db_name": "UMLS",
"db_id": "C0058702"
}
]
},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-t5",
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"text": [
"liver-venous"
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[
101,
113
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],
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"db_id": "C0345904"
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{
"db_name": "UMLS",
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]
},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"oxygen"
],
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[
114,
120
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],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030054"
},
{
"db_name": "UMLS",
"db_id": "C0184633"
}
]
},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-t7",
"type": "umlsterm",
"text": [
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134,
140
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{
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"db_id": "C0030054"
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{
"db_name": "UMLS",
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]
},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-t8",
"type": "umlsterm",
"text": [
"delivery"
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[
141,
149
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],
"normalized": [
{
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"db_id": "C0011209"
}
]
},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-t9",
"type": "umlsterm",
"text": [
"liver"
],
"offsets": [
[
165,
170
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0345904"
},
{
"db_name": "UMLS",
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]
},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-t10",
"type": "umlsterm",
"text": [
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171,
179
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},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-t11",
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180,
185
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]
},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-t12",
"type": "umlsterm",
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223,
234
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},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-t13",
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235,
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},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-t14",
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267,
276
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"db_id": "C0543467"
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"db_name": "UMLS",
"db_id": "C0038895"
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]
},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-t15",
"type": "umlsterm",
"text": [
"liver"
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[
299,
304
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{
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]
},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-t16",
"type": "umlsterm",
"text": [
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[
165,
185
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],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0023901"
}
]
}
] |
[] |
[] |
[
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-r1-t2.1-t4.1",
"type": "affects",
"arg1_id": "DerAnaesthesist.90480224.eng.abstr-s1-t2",
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},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-r2-t6.1-t5.1",
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{
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},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-r4-t4.1-t9.1",
"type": "location_of",
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},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-r5-t9.1-t2.1",
"type": "produces",
"arg1_id": "DerAnaesthesist.90480224.eng.abstr-s1-t9",
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"normalized": []
},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-r6-t7.1-t5.1",
"type": "affects",
"arg1_id": "DerAnaesthesist.90480224.eng.abstr-s1-t7",
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},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-r7-t7.1-t10.1",
"type": "interacts_with",
"arg1_id": "DerAnaesthesist.90480224.eng.abstr-s1-t7",
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},
{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-r8-t2.1-t4.1",
"type": "indicates",
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{
"id": "DerAnaesthesist.90480224.eng.abstr-s1-r9-t2.1-t14.2",
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] |
DerAnaesthesist.90480231.eng.abstr
|
DerAnaesthesist.90480231.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480231.eng.abstr-passage-0",
"type": "abstract",
"text": [
"This case report presents the perioperative management of double-sided hip arthroplasty in a patient ( female , 25 years old ) homozygous for sickle cell anemia ( SS ) . The fraction of sickle hemoglobin ( Hb S ) to total hemoglobin was monitored with an automated cation exchange microcolumn chromatography . The main purpose of ion exchange chromatography is to measure glycated hemoglobin A ( HbA1c) in diabetic patients . Furthermore , as a by-product , this test enables the quantitative assessment of aberrant hemoglobin molecules such as sickle cell hemoglobin Hb S with sufficient precision and selectivity . The standard method , hemoglobin-electrophoresis is more complicated and not generally available . For the perioperative estimation of the risk for sickle cell related complications and as a guide for transfusion therapy , knowledge of preoperative Hb S level is essential . In this case report , the clinical use of a rapid laboratory test at low costs with common equipment in a patient with known homozygous sickle cell anemia is demonstrated ."
],
"offsets": [
[
0,
1064
]
]
}
] |
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] |
DerAnaesthesist.90480242.eng.abstr
|
DerAnaesthesist.90480242.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480242.eng.abstr-passage-0",
"type": "abstract",
"text": [
"There is still controversy on the usefulness of spinal anesthesia for operations performed in the prone or jackknife position . There is about the risk of inadvertent increase of the sensomotory blockade with the patient in the prone position and the difficulty of managing consecutive cardiorespiratory complications or inducing general anesthesia in case of failures . This article reviews the current literature in terms of safety and effectivness of spinal anesthesia for such operations . For lower-limb or perianal operations with limited extension and blood loss , performed in the prone position , spinal anesthesia seems to be a safe , effective and economic technique in patients without severe a cardiac history . Substantial knowledge about the onset time , fixation time , duration of sensomotory block and baricity of the applied local anesthetic is crucial in this setting . Obese patients are at risk for sudden extension of the block when turned into the prone position . Additional narcotics and sedatives should be avoided and continuous monitoring of hemodynamic and respiratory parameters , of the level of the blockade and vigilance of the patient is mandatory ."
],
"offsets": [
[
0,
1184
]
]
}
] |
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DerAnaesthesist.90480290.eng.abstr
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DerAnaesthesist.90480310.eng.abstr
|
DerAnaesthesist.90480310.eng.abstr
|
[
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"Tracheostomy is considered the airway management of choice in long-term ventilated ICU patients . In the last few years , percutaneous dilatational tracheostomy ( PDT ) has been established as an attractive and safe alternative to conventional open tracheostomy . Recently , there is another percutaneous technique according to Fantoni with translaryngeal airway access ( TLT ) available . Our study seeks to evaluate TLT in terms of complications and practicability . In 47 patients of our surgical ICU , elective TLT was performed . Mean operative time was 9.8 +/- 10.9 ( range 6-27 ) minutes . Severe complications , such as bleeding , aspiration or infection of the tracheostoma have never been noted . A slight detoriation of arterial oxygen tension occured in 25 patients intraoperatively , demanding to rise the concentration of inspired oxygen temporarily . However , no patient became hypoxic during the procedure . Since during the procedure gas exchange may worsen , TLT should not be employed in patients whose inspired oxygen concentration exceeds 80% . Despite the fact that severe complications associated with TLT have recently not yet been reported , physicians who perform TLT should be well-trained in the technique of conventional open tracheostomy , too . According to our present data , TLT seems to be an attractive and safe alternative to PDT . Nevertheless , for a definiteve evaluation of TLT , further investigations in larger groups of patients and in the long term seem to be necessary ."
],
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1516
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}
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DerAnaesthesist.90480317.eng.abstr
|
DerAnaesthesist.90480317.eng.abstr
|
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418
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[] |
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DerAnaesthesist.90480359.eng.abstr
|
DerAnaesthesist.90480359.eng.abstr
|
[
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"The additive properties of general and regional anesthetic techniques are brought together in combined anesthesia to minimise side effects of the individual techniques . Despite a wide experience with both used as single anesthetic techniques , no definite recommendations regarding indications , general contraindications and procedure exist for their combination . Beneficial effects on haemodynamics , respiratory function , intestinal motility and postoperative stress response have been demonstrated for a combination of general anesthesia and thoracic epidural anesthesia ( TEA ) . In addition TEA is favourable in the management of postoperative pain , which has advantageous effects on convalescence especially in a high risk patient group . Nevertheless , until now no reduction of perioperative morbidity and mortality has been demonstrated . Since the combination of two anesthesia techniques theoretically increases the rate of complication , the expected benefit for the patient must predominate . To estimate the risks and benefits of combined anesthesia , the anesthesiologist must be familiar with each single method , as well as with the synergistic effects of both techniques in order to evaluate the individual indication ."
],
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[
0,
1242
]
]
}
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DerAnaesthesist.90480373.eng.abstr
|
DerAnaesthesist.90480373.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480373.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Aim of investigation : We examined whether a pre-emptive analgesic effect could be achieved with ropivacaine , which has less cardiovascular and central nervous system toxicity than bupivacaine , in adults undergoing tonsillectomy ."
],
"offsets": [
[
0,
232
]
]
}
] |
[
{
"id": "DerAnaesthesist.90480373.eng.abstr-s1-t1",
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"analgesic"
],
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[
57,
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}
]
},
{
"id": "DerAnaesthesist.90480373.eng.abstr-s1-t2",
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"ropivacaine"
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97,
108
]
],
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}
]
},
{
"id": "DerAnaesthesist.90480373.eng.abstr-s1-t3",
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"text": [
"nervous"
],
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[
153,
160
]
],
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{
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"db_id": "C0027769"
}
]
},
{
"id": "DerAnaesthesist.90480373.eng.abstr-s1-t4",
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"toxicity"
],
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[
168,
176
]
],
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{
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"db_id": "C0600688"
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{
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}
]
},
{
"id": "DerAnaesthesist.90480373.eng.abstr-s1-t5",
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"bupivacaine"
],
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[
182,
193
]
],
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{
"db_name": "UMLS",
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}
]
},
{
"id": "DerAnaesthesist.90480373.eng.abstr-s1-t6",
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"text": [
"adults"
],
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[
199,
205
]
],
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{
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]
},
{
"id": "DerAnaesthesist.90480373.eng.abstr-s1-t7",
"type": "umlsterm",
"text": [
"tonsillectomy"
],
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[
217,
230
]
],
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}
]
},
{
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],
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153,
167
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],
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{
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},
{
"id": "DerAnaesthesist.90480373.eng.abstr-s1-t9",
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"text": [
"central nervous system"
],
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[
145,
167
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0007679"
}
]
}
] |
[] |
[] |
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{
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}
] |
DerAnaesthesist.90480379.eng.abstr
|
DerAnaesthesist.90480379.eng.abstr
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"id": "DerAnaesthesist.90480379.eng.abstr-passage-0",
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"Objective : The aim of the present study was to show the influence of the parameters of gas exchange ( arterial oxygen pressure paO2, arterial oxygen saturation SatO2) and haemodynamics ( arterial systolic and mean blood pressure RRs and MAP ) on the restitution of cognitive functions in geriatric patients scheduled for elective hip arthroplasty ."
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[] |
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] |
DerAnaesthesist.90480387.eng.abstr
|
DerAnaesthesist.90480387.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480387.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The acute liver failure ( ALF ) is a complex syndrome resulting from loss of synthetic and metabolic functions of the liver . Despite recent advances in intensive care medicine patients with severe ALF have a very high mortality and the orthotopic liver transplantation still remains the only proven effective treatment of ALF . Numerous attempts have been made to improve survival by using various extracorporeal support techniques , but none of these therapeutic approaches was able to increase the survival rate . Liver support systems based on detoxification procedures only could not influence the deleterious course of the disease . It is certain that an ideal liver support system should be capable to fulfil the liver's essential synthetic and metabolic functions as well as detoxification and excretion . Over the last years the development of hybrid liver assist devices has aimed at replacing these liver functions and therefore might give an advantage over earlier systems based on detoxification techniques only . This article gives a short review of the various liver support systems and focuses then on the hybrid liver support systems , their construction and the remaining problems after the first clinical applications ."
],
"offsets": [
[
0,
1238
]
]
}
] |
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10,
15
]
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}
]
},
{
"id": "DerAnaesthesist.90480387.eng.abstr-s1-t2",
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],
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]
],
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"functions"
],
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[
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{
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},
{
"id": "DerAnaesthesist.90480387.eng.abstr-s2-t3",
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},
{
"id": "DerAnaesthesist.90480387.eng.abstr-s2-t5",
"type": "umlsterm",
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],
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DerAnaesthesist.90480433.eng.abstr
|
DerAnaesthesist.90480433.eng.abstr
|
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"text": [
"Simulation has gained an important role in medical education and continuing education in the field of anaesthesia and emergency medicine . This article gives background information on how full-scale simulators are applied in medical education as well as in continuing education for advanced anesthesia and scientific applications . Acceptance of training seems enhanced by inclusion of the human factor aspect , since this has proven to be a major source for the development of critical situations in our specialty . Furthermore , drawbacks of the simulators available and the current training availability in Germany is described ."
],
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[
0,
632
]
]
}
] |
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] |
[] |
[] |
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{
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},
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},
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},
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},
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{
"id": "DerAnaesthesist.90480433.eng.abstr-s3-r10-t4.1-t2.1",
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{
"id": "DerAnaesthesist.90480433.eng.abstr-s3-r13-t1.1-t3.1",
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"id": "DerAnaesthesist.90480433.eng.abstr-s3-r14-t1.1-t4.1",
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}
] |
DerAnaesthesist.90480439.eng.abstr
|
DerAnaesthesist.90480439.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480439.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Wound instillation seems to be an easy and preferable way to achieve postoperative analgesia in pediatric hernioplasty . This prospective , randomized and double-blinded pilot-study was initiated to gain preliminary information in order to define the appropriate concentration of local anaesthetic for efficient posthernioplastic analgesia ."
],
"offsets": [
[
0,
341
]
]
}
] |
[
{
"id": "DerAnaesthesist.90480439.eng.abstr-s1-t1",
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"text": [
"Wound"
],
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0,
5
]
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"db_id": "C0021501"
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{
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}
]
},
{
"id": "DerAnaesthesist.90480439.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"postoperative"
],
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69,
82
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]
},
{
"id": "DerAnaesthesist.90480439.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"analgesia"
],
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[
83,
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{
"id": "DerAnaesthesist.90480439.eng.abstr-s2-t1",
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"concentration"
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263,
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{
"id": "DerAnaesthesist.90480439.eng.abstr-s2-t2",
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"text": [
"anaesthetic"
],
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286,
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{
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"analgesia"
],
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330,
339
]
],
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},
{
"id": "DerAnaesthesist.90480439.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"local anaesthetic"
],
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280,
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"db_id": "C0002934"
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{
"db_name": "UMLS",
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]
}
] |
[] |
[] |
[
{
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"type": "associated_with",
"arg1_id": "DerAnaesthesist.90480439.eng.abstr-s2-t3",
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},
{
"id": "DerAnaesthesist.90480439.eng.abstr-s1-r2-t3.1-t1.1",
"type": "associated_with",
"arg1_id": "DerAnaesthesist.90480439.eng.abstr-s2-t3",
"arg2_id": "DerAnaesthesist.90480439.eng.abstr-s2-t1",
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},
{
"id": "DerAnaesthesist.90480439.eng.abstr-s2-r1-t3.1-t1.1",
"type": "affects",
"arg1_id": "DerAnaesthesist.90480439.eng.abstr-s2-t3",
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},
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"id": "DerAnaesthesist.90480439.eng.abstr-s2-r2-t4.2-t1.1",
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{
"id": "DerAnaesthesist.90480439.eng.abstr-s2-r4-t3.1-t1.1",
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},
{
"id": "DerAnaesthesist.90480439.eng.abstr-s2-r5-t4.1-t1.1",
"type": "affects",
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"normalized": []
},
{
"id": "DerAnaesthesist.90480439.eng.abstr-s2-r6-t4.2-t1.1",
"type": "affects",
"arg1_id": "DerAnaesthesist.90480439.eng.abstr-s2-t4",
"arg2_id": "DerAnaesthesist.90480439.eng.abstr-s2-t1",
"normalized": []
},
{
"id": "DerAnaesthesist.90480439.eng.abstr-s2-r7-t3.1-t4.1",
"type": "uses",
"arg1_id": "DerAnaesthesist.90480439.eng.abstr-s2-t3",
"arg2_id": "DerAnaesthesist.90480439.eng.abstr-s2-t4",
"normalized": []
}
] |
DerAnaesthesist.90480444.eng.abstr
|
DerAnaesthesist.90480444.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480444.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The news of success in ether anesthesia on 16 October 1846 in Boston spread like wildfire through Europe . In the German-speaking countries , the national newspapers as conveyers of the development played a prominent role ; this was especially the case for the Augsburger Allgemeine Zeitung whose correspondent , Aloys Martin [ 1 ] , was a medical professional . The function of local newspapers has not yet been investigated . This was to be remedied by examining both of Bamberg's local papers . All issues from 01.01. to 31.04.1847 were surveyed with respect to relevant announcements . These were then catalogued according to date , extent and contents . Starting on 22.01.1847 , the events outside of and in Bamberg were reported on in 26 notices and articles of just a few lines to half a page and in advertisements ; Aloys Martin also appears on the scene . Thus , the local press in Bamberg also informed its readers early and regularly on the discovery of ether and the succeeding events ."
],
"offsets": [
[
0,
998
]
]
}
] |
[
{
"id": "DerAnaesthesist.90480444.eng.abstr-s1-t1",
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"news"
],
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[
4,
8
]
],
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"db_name": "UMLS",
"db_id": "C0282425"
}
]
},
{
"id": "DerAnaesthesist.90480444.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"ether"
],
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[
23,
28
]
],
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{
"db_name": "UMLS",
"db_id": "C0014994"
},
{
"db_name": "UMLS",
"db_id": "C0014996"
}
]
},
{
"id": "DerAnaesthesist.90480444.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"anesthesia"
],
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[
29,
39
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"db_name": "UMLS",
"db_id": "C0002903"
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},
{
"id": "DerAnaesthesist.90480444.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"October"
],
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[
46,
53
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"db_name": "UMLS",
"db_id": "C0029279"
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{
"id": "DerAnaesthesist.90480444.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"Boston"
],
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[
62,
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"db_id": "C0006037"
}
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"id": "DerAnaesthesist.90480444.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"Europe"
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98,
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"db_id": "C0015176"
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"id": "DerAnaesthesist.90480444.eng.abstr-s2-t1",
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"national"
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{
"id": "DerAnaesthesist.90480444.eng.abstr-s2-t2",
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"text": [
"newspapers"
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155,
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"db_id": "C0027989"
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},
{
"id": "DerAnaesthesist.90480444.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"development"
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186,
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{
"db_name": "UMLS",
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"db_name": "UMLS",
"db_id": "C0020119"
}
]
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{
"id": "DerAnaesthesist.90480444.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"role"
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[
217,
221
]
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"db_name": "UMLS",
"db_id": "C0035820"
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]
},
{
"id": "DerAnaesthesist.90480444.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"Augsburger"
],
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261,
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"db_id": "C0230779"
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"id": "DerAnaesthesist.90480444.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"function"
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367,
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DerAnaesthesist.90480455.eng.abstr
|
DerAnaesthesist.90480455.eng.abstr
|
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"id": "DerAnaesthesist.90480455.eng.abstr-passage-0",
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"Status epilepticus ( SE ) is defined as a seizure persisting over 10 min or repeated seizures without recovery between the attacks . SE is a frequent medical emergency with a high mortality , requiring aggressive and prompt treatment and a systematic , coordinated approach . A variety of new drugs has been introduced for the treatment of SE , including midazolam , propofol , fosphenytoin , and valproate . However , there are very few controlled clinical trials . Benzodiazepines are highly effective in terminating the SE in most patients and should be used as initial treatment . Phenytoin and Phenobarbital are employed if Benzodiazepines are not successful . The optimal therapeutic approach for the patient with refractory SE remains to be defined . Refractory SE has a poor prognosis and should be treated in a specialized ICU with EEG-monitoring . Barbiturates , propofol , and midazolam are substances that can be used alternatively ."
],
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[
0,
945
]
]
}
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[] |
[] |
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DerAnaesthesist.90480507.eng.abstr
|
DerAnaesthesist.90480507.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480507.eng.abstr-passage-0",
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"After surgical operations delirium can occur as a serious and possible lethal complication in about 5-15% of patients . Additionally , risk factors such as old age , polymedication , organic and psychiatric diseases raise the incidence . After open-heart- and orthopedic surgery more than half of the patients are affected . Delirium has negative effects on postoperative mobilization and reconvalescence and prolongs treatment on the ward . It is discussed in the literature that delirium may induce dementia in older patients ."
],
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0,
529
]
]
}
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[] |
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DerAnaesthesist.90480519.eng.abstr
|
DerAnaesthesist.90480519.eng.abstr
|
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}
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[] |
[] |
[] |
DerAnaesthesist.90480523.eng.abstr
|
DerAnaesthesist.90480523.eng.abstr
|
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[] |
[] |
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}
] |
DerAnaesthesist.90480538.eng.abstr
|
DerAnaesthesist.90480538.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480538.eng.abstr-passage-0",
"type": "abstract",
"text": [
"We report a case of carbon dioxide ( CO2) embolism in a 52-year-old man during a laparoscopic cholecystectomy , which caused an accidental CO2-insufflation in a vessel despite exact control of the Verres needle . The first manifestations were two drops of the partial pressure of endtidal carbon dioxide ( Petco2 ) from 34 mmHg to 13 mmHg and again from 37 mmHg to 11 mmHg , followed by pulseless ventricular tachycardia . It was possible to achieve resuscitation and a recompensation of the right heart failure with drug therapy . After successful resuscitation and restoration of a stable hemodynamic situation , an abrupt increase in the Petco2 from 11 mmHg to 52 mmHg was noted . This increase of Petco2 could be interpreted as the reinstallation of circulation and the amount of CO2 in the organism after carbon dioxide embolism ."
],
"offsets": [
[
0,
835
]
]
}
] |
[
{
"id": "DerAnaesthesist.90480538.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"carbon"
],
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20,
26
]
],
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{
"db_name": "UMLS",
"db_id": "C0007009"
}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"embolism"
],
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[
42,
50
]
],
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{
"db_name": "UMLS",
"db_id": "C0013922"
}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s1-t3",
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"text": [
"man"
],
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[
68,
71
]
],
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{
"db_name": "UMLS",
"db_id": "C0025266"
},
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"db_id": "C0024554"
}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"cholecystectomy"
],
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[
94,
109
]
],
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"db_id": "C0008320"
}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s1-t5",
"type": "umlsterm",
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"CO2-insufflation"
],
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139,
155
]
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"db_id": "C0007012"
}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s1-t6",
"type": "umlsterm",
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"CO2-insufflation"
],
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139,
155
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}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s1-t7",
"type": "umlsterm",
"text": [
"vessel"
],
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[
161,
167
]
],
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{
"db_name": "UMLS",
"db_id": "C0005847"
},
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}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s1-t8",
"type": "umlsterm",
"text": [
"exact"
],
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176,
181
]
],
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{
"db_name": "UMLS",
"db_id": "C0059927"
}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s1-t9",
"type": "umlsterm",
"text": [
"control"
],
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[
182,
189
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0243148"
}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s1-t10",
"type": "umlsterm",
"text": [
"needle"
],
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[
204,
210
]
],
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{
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}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s1-t11",
"type": "umlsterm",
"text": [
"carbon dioxide"
],
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[
20,
34
]
],
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{
"db_name": "UMLS",
"db_id": "C0007012"
}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"pressure"
],
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[
268,
276
]
],
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}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"carbon"
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295
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}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"Petco2"
],
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306,
312
]
],
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]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s2-t4",
"type": "umlsterm",
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"Petco2"
],
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306,
312
]
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]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"tachycardia"
],
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409,
420
]
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},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s2-t6",
"type": "umlsterm",
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"partial pressure"
],
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},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s2-t7",
"type": "umlsterm",
"text": [
"carbon dioxide"
],
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289,
303
]
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}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s2-t8",
"type": "umlsterm",
"text": [
"ventricular tachycardia"
],
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397,
420
]
],
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"db_id": "C0042514"
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]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s3-t1",
"type": "umlsterm",
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"resuscitation"
],
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[
450,
463
]
],
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{
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"db_id": "C0035273"
}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"right"
],
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497
]
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"db_id": "C0035621"
}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"heart"
],
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[
498,
503
]
],
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"db_id": "C0018787"
}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"drug"
],
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517,
521
]
],
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"db_id": "C0013227"
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]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s3-t5",
"type": "umlsterm",
"text": [
"therapy"
],
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522,
529
]
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},
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]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s3-t6",
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],
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517,
529
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},
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}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"resuscitation"
],
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549,
562
]
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{
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}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"hemodynamic"
],
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[
591,
602
]
],
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]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"Petco2"
],
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641,
647
]
],
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]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s4-t4",
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],
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641,
647
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],
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]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s5-t1",
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"Petco2"
],
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]
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]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s5-t2",
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],
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707
]
],
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}
]
},
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"circulation"
],
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754,
765
]
],
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}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s5-t4",
"type": "umlsterm",
"text": [
"CO2"
],
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784,
787
]
],
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}
]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s5-t5",
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"organism"
],
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{
"id": "DerAnaesthesist.90480538.eng.abstr-s5-t6",
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]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s5-t7",
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"embolism"
],
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825,
833
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]
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s5-t8",
"type": "umlsterm",
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"carbon dioxide"
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824
]
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"normalized": [
{
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}
]
}
] |
[] |
[] |
[
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"id": "DerAnaesthesist.90480538.eng.abstr-s1-r1-t7.2-t2.1",
"type": "causes",
"arg1_id": "DerAnaesthesist.90480538.eng.abstr-s1-t7",
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"normalized": []
},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s1-r2-t2.1-t6.1",
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},
{
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"type": "interacts_with",
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},
{
"id": "DerAnaesthesist.90480538.eng.abstr-s1-r4-t7.1-t2.1",
"type": "location_of",
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{
"id": "DerAnaesthesist.90480538.eng.abstr-s1-r6-t7.2-t8.1",
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DerAnaesthesist.90480542.eng.abstr
|
DerAnaesthesist.90480542.eng.abstr
|
[
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"text": [
"Many patients consulting medical emergency services make the initial contact because of psychiatric emergency situations . However , emergency physicians and their assistants are usually not sufficiently experienced in psychiatry . Therefore , psychiatric emergencies are sometimes only reluctantly accepted or inadequately treated by these services . Our present contribution aims at improving this situation . It gives a review of the main diagnostic groups concerned , their symptomatology and psychopathology , and offers some advice with regard to empathic verbal interventions and counselling in those emergency situations ."
],
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0,
630
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}
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] |
[] |
[] |
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DerAnaesthesist.90480593.eng.abstr
|
DerAnaesthesist.90480593.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480593.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A treatment procedure requires the consent of the patient , but this is legally effective only if he is capable of giving his consent and can be informed accordingly . Because of demographic development and the progress of medicine , the number of patients who are not able to give their consent is increasing . In practice , we make do with the presumed consent of the patient or , for procedures that can wait , with the consent of legitimate family members . An initiative action is suggested by physicians and hospitals that should reduce this gray zone and the forensic risks drastically ."
],
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[
0,
594
]
]
}
] |
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"physicians"
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"risks"
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{
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"db_id": "C0035647"
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]
}
] |
[] |
[] |
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"id": "DerAnaesthesist.90480593.eng.abstr-s3-r6-t4.1-t2.2",
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] |
DerAnaesthesist.90480602.eng.abstr
|
DerAnaesthesist.90480602.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480602.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Objectives : Muscle relaxants have different pharmacodynamic profiles in various muscles . Therefore , results obtained for one muscle cannot be extrapolated to other muscles . In the adductor pollicis muscle cisatracurium exerts a pharmacodynamic profile comparable to atracurium , despite the known difference in onset time . However , studies evaluating the neuromuscular effect of cisatracurium in different muscles are lacking . Accordingly , this study compares the pharmacodynamic profile of cisatracurium and atracurium in the orbicularis oculi muscle ( OO ) - which shows a neuromuscular course similar to the diaphragm and the laryngeal muscles - and the adductor pollicis muscle ( AP ) ."
],
"offsets": [
[
0,
698
]
]
}
] |
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"Objectives"
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0,
10
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{
"id": "DerAnaesthesist.90480602.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"Muscle"
],
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[
13,
19
]
],
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{
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},
{
"id": "DerAnaesthesist.90480602.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"muscles"
],
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81,
88
]
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{
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{
"id": "DerAnaesthesist.90480602.eng.abstr-s2-t1",
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"muscle"
],
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128,
134
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{
"id": "DerAnaesthesist.90480602.eng.abstr-s2-t2",
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"muscles"
],
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167,
174
]
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{
"id": "DerAnaesthesist.90480602.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"muscle"
],
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202,
208
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{
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]
},
{
"id": "DerAnaesthesist.90480602.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"cisatracurium"
],
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[
209,
222
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],
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{
"id": "DerAnaesthesist.90480602.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"atracurium"
],
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270,
280
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},
{
"id": "DerAnaesthesist.90480602.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"time"
],
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[
321,
325
]
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{
"db_name": "UMLS",
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]
},
{
"id": "DerAnaesthesist.90480602.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"cisatracurium"
],
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[
385,
398
]
],
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{
"db_name": "UMLS",
"db_id": "C0530103"
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},
{
"id": "DerAnaesthesist.90480602.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"muscles"
],
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412,
419
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{
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},
{
"id": "DerAnaesthesist.90480602.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"cisatracurium"
],
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499,
512
]
],
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{
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]
},
{
"id": "DerAnaesthesist.90480602.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"atracurium"
],
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517,
527
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],
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]
},
{
"id": "DerAnaesthesist.90480602.eng.abstr-s5-t3",
"type": "umlsterm",
"text": [
"oculi"
],
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[
547,
552
]
],
"normalized": [
{
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"db_id": "C0015392"
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]
},
{
"id": "DerAnaesthesist.90480602.eng.abstr-s5-t4",
"type": "umlsterm",
"text": [
"muscle"
],
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553,
559
]
],
"normalized": [
{
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]
},
{
"id": "DerAnaesthesist.90480602.eng.abstr-s5-t5",
"type": "umlsterm",
"text": [
"diaphragm"
],
"offsets": [
[
619,
628
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0042241"
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{
"db_name": "UMLS",
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]
},
{
"id": "DerAnaesthesist.90480602.eng.abstr-s5-t6",
"type": "umlsterm",
"text": [
"muscles"
],
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647,
654
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},
{
"id": "DerAnaesthesist.90480602.eng.abstr-s5-t7",
"type": "umlsterm",
"text": [
"muscle"
],
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683,
689
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],
"normalized": [
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]
},
{
"id": "DerAnaesthesist.90480602.eng.abstr-s5-t8",
"type": "umlsterm",
"text": [
"laryngeal muscles"
],
"offsets": [
[
637,
654
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0023054"
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]
}
] |
[] |
[] |
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"id": "DerAnaesthesist.90480602.eng.abstr-s5-r7-t1.1-t5.1",
"type": "disrupts",
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{
"id": "DerAnaesthesist.90480602.eng.abstr-s5-r8-t8.1-t1.1",
"type": "produces",
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{
"id": "DerAnaesthesist.90480602.eng.abstr-s5-r9-t8.1-t4.1",
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"type": "developmental_form_of",
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{
"id": "DerAnaesthesist.90480602.eng.abstr-s5-r11-t5.1-t6.1",
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] |
DerAnaesthesist.90480613.eng.abstr
|
DerAnaesthesist.90480613.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480613.eng.abstr-passage-0",
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"text": [
"Objectives : Despite increasing use of oral opioids in cancer and non cancer pain , little is known about the effects of long-term opioid therapy on psychomotor performance . This study was designed to investigate the effects of long-term opioid analgesia on attention and reaction time in cancer pain and in non-malignant pain ."
],
"offsets": [
[
0,
329
]
]
}
] |
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] |
[] |
[] |
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DerAnaesthesist.90480625.eng.abstr
|
DerAnaesthesist.90480625.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480625.eng.abstr-passage-0",
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0,
350
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] |
[] |
[] |
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},
{
"id": "DerAnaesthesist.90480625.eng.abstr-s1-r18-t6.2-t7.1",
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{
"id": "DerAnaesthesist.90480625.eng.abstr-s1-r19-t2.1-t8.1",
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},
{
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{
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] |
DerAnaesthesist.90480630.eng.abstr
|
DerAnaesthesist.90480630.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480630.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Goal : Intracranial pressure ( ICP ) monitoring has a key role within the neuromonitoring , although ICP does not monitor processes of the central neuron directly and only with delay . One of the important factors in ICP monitoring is measurement accuracy . For a better understanding of ICP probes and their differences , the function and principles of intracranial pressure transducers should be evaluated from a technical point of view ."
],
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[
0,
440
]
]
}
] |
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271,
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"probes"
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292,
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}
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"function"
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327,
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"id": "DerAnaesthesist.90480630.eng.abstr-s3-t4",
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"pressure"
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367,
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}
]
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{
"id": "DerAnaesthesist.90480630.eng.abstr-s3-t5",
"type": "umlsterm",
"text": [
"transducers"
],
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376,
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]
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354,
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"pressure transducers"
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367,
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]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0040662"
}
]
}
] |
[] |
[] |
[
{
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"type": "location_of",
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{
"id": "DerAnaesthesist.90480630.eng.abstr-s1-r2-t2.1-t5.1",
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},
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},
{
"id": "DerAnaesthesist.90480630.eng.abstr-s3-r2-t1.1-t3.1",
"type": "affects",
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},
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"id": "DerAnaesthesist.90480630.eng.abstr-s3-r3-t1.1-t6.1",
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},
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},
{
"id": "DerAnaesthesist.90480630.eng.abstr-s3-r5-t2.1-t3.1",
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},
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"id": "DerAnaesthesist.90480630.eng.abstr-s3-r6-t1.1-t6.1",
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},
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},
{
"id": "DerAnaesthesist.90480630.eng.abstr-s3-r8-t6.1-t1.1",
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"normalized": []
},
{
"id": "DerAnaesthesist.90480630.eng.abstr-s3-r9-t1.1-t3.1",
"type": "measurement_of",
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},
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},
{
"id": "DerAnaesthesist.90480630.eng.abstr-s3-r11-t3.1-t6.1",
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},
{
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},
{
"id": "DerAnaesthesist.90480630.eng.abstr-s3-r13-t3.1-t1.1",
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},
{
"id": "DerAnaesthesist.90480630.eng.abstr-s3-r14-t2.1-t1.1",
"type": "affects",
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"normalized": []
},
{
"id": "DerAnaesthesist.90480630.eng.abstr-s3-r15-t2.1-t1.1",
"type": "interacts_with",
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"arg2_id": "DerAnaesthesist.90480630.eng.abstr-s3-t1",
"normalized": []
}
] |
DerAnaesthesist.90480639.eng.abstr
|
DerAnaesthesist.90480639.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480639.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A 72-year-old patient received 0.1 mg morphine by the intrathecal route and 2x1.5 mg midazolam as adjuvant therapy . Severe respiratory depression and somnolence supervened 3.5 h later , which lasted over the next 24 h and necessitated intubation and mechanical ventilation . Continuous administration of > 6 mg naloxone to antagonize the supposed effect of the morphine had no effect . The patient's condition was not normalized until a single dose of 0.3 mg flumazenil was administered . For the time being , especially in the case of elderly patients , we recommend that strict indications are adhered to when intrathecal administration of morphine is considered and that less than 0.1 mg morphine is given . Diazepines should be avoided . Respiration should be monitored for quite some time ."
],
"offsets": [
[
0,
796
]
]
}
] |
[
{
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"patient"
],
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[
14,
21
]
],
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}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"morphine"
],
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[
38,
46
]
],
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{
"db_name": "UMLS",
"db_id": "C0026549"
}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"midazolam"
],
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[
85,
94
]
],
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{
"db_name": "UMLS",
"db_id": "C0026056"
}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"adjuvant"
],
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[
98,
106
]
],
"normalized": [
{
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"db_id": "C0001551"
}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"therapy"
],
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[
107,
114
]
],
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{
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"db_id": "C0087111"
},
{
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"db_id": "C0039798"
}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"depression"
],
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[
136,
146
]
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{
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"db_id": "C0011570"
}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"somnolence"
],
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[
151,
161
]
],
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{
"db_name": "UMLS",
"db_id": "C0013144"
}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"intubation"
],
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[
236,
246
]
],
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{
"db_name": "UMLS",
"db_id": "C0021925"
}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"ventilation"
],
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[
262,
273
]
],
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{
"db_name": "UMLS",
"db_id": "C0042491"
},
{
"db_name": "UMLS",
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}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"mechanical ventilation"
],
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[
251,
273
]
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{
"db_name": "UMLS",
"db_id": "C0042494"
}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"administration"
],
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[
287,
301
]
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{
"db_name": "UMLS",
"db_id": "C0001554"
}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"naloxone"
],
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[
312,
320
]
],
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{
"db_name": "UMLS",
"db_id": "C0027358"
}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"morphine"
],
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[
362,
370
]
],
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{
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}
]
},
{
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"type": "umlsterm",
"text": [
"single"
],
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[
438,
444
]
],
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{
"db_name": "UMLS",
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}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"flumazenil"
],
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[
460,
470
]
],
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{
"db_name": "UMLS",
"db_id": "C0016293"
}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"time"
],
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[
498,
502
]
],
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}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"elderly"
],
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[
537,
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]
],
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"db_id": "C0001792"
}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s5-t3",
"type": "umlsterm",
"text": [
"patients"
],
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[
545,
553
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s5-t4",
"type": "umlsterm",
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"administration"
],
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[
625,
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]
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]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s5-t5",
"type": "umlsterm",
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"morphine"
],
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[
643,
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]
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{
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}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s5-t6",
"type": "umlsterm",
"text": [
"morphine"
],
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[
692,
700
]
],
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{
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}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s7-t1",
"type": "umlsterm",
"text": [
"Respiration"
],
"offsets": [
[
743,
754
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0035203"
},
{
"db_name": "UMLS",
"db_id": "C0282636"
}
]
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s7-t2",
"type": "umlsterm",
"text": [
"time"
],
"offsets": [
[
790,
794
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0040223"
}
]
}
] |
[] |
[] |
[
{
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"type": "interacts_with",
"arg1_id": "DerAnaesthesist.90480639.eng.abstr-s5-t4",
"arg2_id": "DerAnaesthesist.90480639.eng.abstr-s7-t2",
"normalized": []
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s1-r2-t3.1-t4.1",
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},
{
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{
"id": "DerAnaesthesist.90480639.eng.abstr-s1-r4-t5.1-t4.1",
"type": "uses",
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"arg2_id": "DerAnaesthesist.90480639.eng.abstr-s5-t4",
"normalized": []
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s1-r5-t3.1-t2.1",
"type": "interacts_with",
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"arg2_id": "DerAnaesthesist.90480639.eng.abstr-s7-t2",
"normalized": []
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s1-r6-t2.1-t4.1",
"type": "interacts_with",
"arg1_id": "DerAnaesthesist.90480639.eng.abstr-s7-t2",
"arg2_id": "DerAnaesthesist.90480639.eng.abstr-s5-t4",
"normalized": []
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s1-r7-t5.1-t1.1",
"type": "affects",
"arg1_id": "DerAnaesthesist.90480639.eng.abstr-s5-t5",
"arg2_id": "DerAnaesthesist.90480639.eng.abstr-s7-t1",
"normalized": []
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s1-r8-t1.1-t5.1",
"type": "performs",
"arg1_id": "DerAnaesthesist.90480639.eng.abstr-s7-t1",
"arg2_id": "DerAnaesthesist.90480639.eng.abstr-s5-t5",
"normalized": []
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s1-r9-t2.1-t3.1",
"type": "interacts_with",
"arg1_id": "DerAnaesthesist.90480639.eng.abstr-s7-t2",
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"normalized": []
},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s1-r10-t4.1-t3.1",
"type": "interacts_with",
"arg1_id": "DerAnaesthesist.90480639.eng.abstr-s5-t4",
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{
"id": "DerAnaesthesist.90480639.eng.abstr-s1-r11-t5.1-t2.1",
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{
"id": "DerAnaesthesist.90480639.eng.abstr-s2-r1-t4.1-t4.2",
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},
{
"id": "DerAnaesthesist.90480639.eng.abstr-s2-r2-t2.1-t4.2",
"type": "evaluation_of",
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{
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{
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{
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DerAnaesthesist.90480698.eng.abstr
|
DerAnaesthesist.90480698.eng.abstr
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[] |
[] |
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DerAnaesthesist.90480705.eng.abstr
|
DerAnaesthesist.90480705.eng.abstr
|
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[] |
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DerAnaesthesist.90480713.eng.abstr
|
DerAnaesthesist.90480713.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480713.eng.abstr-passage-0",
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],
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[
0,
169
]
]
}
] |
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136,
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] |
[] |
[] |
[
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DerAnaesthesist.90480771.eng.abstr
|
DerAnaesthesist.90480771.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480771.eng.abstr-passage-0",
"type": "abstract",
"text": [
"For many decades , heparins have been used successfully for prophylaxis and treatment of thromboembolic complications world-wide . Although heparin-induced thrombocytopenia ( HIT Type II ) is a well-known adverse effect of heparin therapy , thromboembolic complications during heparin therapy are rarely diagnosed exactly to be related to HIT . At present an immunologic etiology of HIT by generation of multimodal immune complexes against a neo antigen of heparin and platelet factor 4 is equivocally accepted . The incidence of HIT seems to be related to the type of heparin ( unfractioned/low molecular weight ) or other underlying risks such as peripheral occlusive vessel disease . Mortality and complications resulting from HIT is reported to be about 20-30% each . For diagnosis of HIT Type II , clinical observation and simultaneous laboratory testing are essential . Discontinuation of heparin is a simple and essential maneuvre , and anticoagulation has to be continued by alternative drugs . The heparinoid danaparoid-sodium and the thrombin inhibitor recombinant hirudin have been used successfully world-wide for treatment in many patients with HIT Type II including cardiopulmonary bypass surgery or renal replacement procedures . Furthermore , other therapeutical alternatives ( e.g. immuneglobulins , prostaglandines ) exist . Randomised controlled studies have to evaluate which drug has to be preferred in the future including risk/ benefit ratio . The need of supplementary surgical procedures ( e.g. embolectomy ) depends on the individual clinical status . The patients have to be informed in detail about their underlying disease and further deleterious consequences of re-exposition with heparin . HIT should be recorded in an emergency certificate and the national Committee on Drugs should be informed about this severe side effect of heparin therapy ."
],
"offsets": [
[
0,
1877
]
]
}
] |
[
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{
"id": "DerAnaesthesist.90480771.eng.abstr-s2-t4",
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DerAnaesthesist.90480786.eng.abstr
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DerAnaesthesist.90480786.eng.abstr
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[] |
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DerAnaesthesist.90480802.eng.abstr
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DerAnaesthesist.90480802.eng.abstr
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DerAnaesthesist.90480807.eng.abstr
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DerAnaesthesist.90480807.eng.abstr
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DerAnaesthesist.90480813.eng.abstr
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DerAnaesthesist.90480813.eng.abstr
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DerAnaesthesist.90480858.eng.abstr
|
DerAnaesthesist.90480858.eng.abstr
|
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"id": "DerAnaesthesist.90480858.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Stroke is the third leading cause of death and number one cause of disability in industrialised countries . Studies into the pathophysiology of acute ischaemic stroke have indicated that treatment options are likely to be optimized when early signs of stroke are recognized and treatment is initiated within 3 hours from symptom onset . Therefore , new conceptions heading towards early diagnosis , fast preclinical treatment , structured diagnostics , immediate initiation of acute therapy as well as early initiation of rehabilitation are required . It is well known that , for most patients , there is a long delay between the onset of symptoms and the start of therapy . Many factors are responsible for the time delay : signs and symptoms often go unrecognized and/or minimized by patients , relatives and bystanders . Unlike trauma or myocardial infarction , stroke is not given a high priority by medical staff and/or emergency medical services ( EMS ) . Although a small number of strike patients is treated as emergency and attended to by the emergency medical services within this time window , this number could easily be increased by intensified public and emergency personnel education . At present the standard of care by the EMS personnel includes adequate cerebral oxygenation , treatment of cardiac arrhythmia , management of hypertension as well as therapy of hyperglycemia and hyperthermia . For the future , we hope that emergency medical services will be able to initiate therapies which must be administered within the first few hours of acute stroke after onset of symptoms . Early notification of hospitals would enable a particular stroke team to be present at the patient's admission ."
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DerAnaesthesist.90480871.eng.abstr
|
DerAnaesthesist.90480871.eng.abstr
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[
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[] |
[] |
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DerAnaesthesist.90480876.eng.abstr
|
DerAnaesthesist.90480876.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480876.eng.abstr-passage-0",
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[] |
[] |
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DerAnaesthesist.90480884.eng.abstr
|
DerAnaesthesist.90480884.eng.abstr
|
[
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] |
[] |
[] |
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}
] |
DerAnaesthesist.90480896.eng.abstr
|
DerAnaesthesist.90480896.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480896.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In a 65 years old male patient 38 cc of a 7.45% potassium chloride-solution was inadvertently infused within 3 hours into an epidural catheter on the first postoperative day . The epidural potassium chloride administration resulted in a paresis and painful paraesthesia of the patient's legs and a level of sensory blockade to TH 11. Furthermore vegetative symptoms like hypertension and tachycardia were observed . For therapy a single bolus of 40 mg dexamethasone was administered intravenously followed by an epidural infusion of sodiumchloride 0,9% 99 cc/h for several hours . About 6 hours after the start of infusion all symptoms had disappeared . It is proposed that the use of colour-coded epidural catheter devices and coloured electrolyte solutions as well as infusion-pumps with a larger reservoir that reduce the frequency of syringe changes would be helpful in avoiding such complications ."
],
"offsets": [
[
0,
903
]
]
}
] |
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{
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{
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{
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189,
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{
"id": "DerAnaesthesist.90480896.eng.abstr-s2-t2",
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"id": "DerAnaesthesist.90480896.eng.abstr-s2-t4",
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"id": "DerAnaesthesist.90480896.eng.abstr-s2-t10",
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],
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189,
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},
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"painful paraesthesia"
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]
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{
"id": "DerAnaesthesist.90480896.eng.abstr-s3-t2",
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]
},
{
"id": "DerAnaesthesist.90480896.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"dexamethasone"
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{
"id": "DerAnaesthesist.90480896.eng.abstr-s3-t4",
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{
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"normalized": [
{
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]
}
] |
[] |
[] |
[
{
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"type": "property_of",
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"id": "DerAnaesthesist.90480896.eng.abstr-s5-r13-t6.1-t8.1",
"type": "treats",
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},
{
"id": "DerAnaesthesist.90480896.eng.abstr-s5-r14-t5.1-t1.1",
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"normalized": []
}
] |
DerAnaesthesist.90480900.eng.abstr
|
DerAnaesthesist.90480900.eng.abstr
|
[
{
"id": "DerAnaesthesist.90480900.eng.abstr-passage-0",
"type": "abstract",
"text": [
"We report a complication during the insertion time of a central venous catheter in a patient with intracerebral bleeding . This complication was caused by an inadvertent dislocation of a subclavian catheter . Hydromediastinum and bilateral hydrothorax developed . There was a clear diagnosis followed by removal of the central venous catheter after radiological investigations could explain the cause of the complication and the clinical symptoms . In the course of events mediastinitis was diagnosed . The clinical condition improved under antibiotic therapy . The patient could be transferred to another clinical unit for endovascular treatment of an arterio-venous cerebral malformation ."
],
"offsets": [
[
0,
691
]
]
}
] |
[
{
"id": "DerAnaesthesist.90480900.eng.abstr-s1-t1",
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12,
24
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{
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]
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{
"id": "DerAnaesthesist.90480900.eng.abstr-s1-t3",
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71,
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{
"id": "DerAnaesthesist.90480900.eng.abstr-s1-t4",
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"patient"
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85,
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{
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128,
140
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},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s2-t2",
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"dislocation"
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170,
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}
]
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s2-t3",
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"text": [
"catheter"
],
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198,
206
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],
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"db_name": "UMLS",
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}
]
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s3-t1",
"type": "umlsterm",
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"Hydromediastinum"
],
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209,
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]
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s3-t2",
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"Hydromediastinum"
],
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209,
225
]
],
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{
"db_name": "UMLS",
"db_id": "C0025066"
}
]
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"hydrothorax"
],
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[
240,
251
]
],
"normalized": [
{
"db_name": "UMLS",
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}
]
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s4-t1",
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"diagnosis"
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282,
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]
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s4-t2",
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334,
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]
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s4-t3",
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"cause"
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395,
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],
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{
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]
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s4-t4",
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408,
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{
"id": "DerAnaesthesist.90480900.eng.abstr-s4-t5",
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438,
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{
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]
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s5-t1",
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"text": [
"mediastinitis"
],
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473,
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],
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]
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s6-t1",
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"antibiotic"
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{
"id": "DerAnaesthesist.90480900.eng.abstr-s6-t2",
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552,
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}
]
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s7-t1",
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"patient"
],
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[
566,
573
]
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{
"db_name": "UMLS",
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{
"id": "DerAnaesthesist.90480900.eng.abstr-s7-t2",
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]
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s7-t3",
"type": "umlsterm",
"text": [
"malformation"
],
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[
677,
689
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0000768"
},
{
"db_name": "UMLS",
"db_id": "C0243070"
}
]
}
] |
[] |
[] |
[
{
"id": "DerAnaesthesist.90480900.eng.abstr-s1-r1-t1.1-t3.1",
"type": "occurs_in",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s7-t1",
"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s7-t3",
"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s1-r2-t3.1-t1.1",
"type": "treats",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s7-t3",
"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s7-t1",
"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s2-r1-t3.1-t1.1",
"type": "treats",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s7-t3",
"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s7-t1",
"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s3-r1-t2.1-t3.1",
"type": "location_of",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s7-t2",
"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s7-t3",
"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s3-r2-t3.1-t1.1",
"type": "produces",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s7-t3",
"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s7-t1",
"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s3-r3-t1.1-t3.1",
"type": "affects",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s7-t1",
"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s7-t3",
"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s4-r1-t4.1-t1.1",
"type": "associated_with",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s4-t4",
"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s7-t1",
"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s4-r2-t2.1-t4.1",
"type": "treats",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s7-t2",
"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s4-t4",
"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s4-r3-t4.1-t5.1",
"type": "associated_with",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s4-t4",
"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s4-t5",
"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s4-r4-t1.1-t4.1",
"type": "associated_with",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s7-t1",
"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s4-t4",
"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s4-r5-t5.1-t4.1",
"type": "associated_with",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s4-t5",
"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s4-t4",
"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s4-r6-t2.1-t5.1",
"type": "treats",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s7-t2",
"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s4-t5",
"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s4-r7-t1.1-t2.1",
"type": "uses",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s7-t1",
"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s7-t2",
"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s6-r1-t2.1-t1.1",
"type": "uses",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s7-t2",
"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s7-t1",
"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s7-r1-t1.1-t2.1",
"type": "performs",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s7-t1",
"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s7-t2",
"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s7-r2-t2.1-t3.2",
"type": "associated_with",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s7-t2",
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"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s7-r3-t3.2-t2.1",
"type": "associated_with",
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},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s7-r4-t3.2-t1.1",
"type": "occurs_in",
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"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s7-t1",
"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s7-r5-t2.1-t1.1",
"type": "occurs_in",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s7-t2",
"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s7-t1",
"normalized": []
},
{
"id": "DerAnaesthesist.90480900.eng.abstr-s7-r6-t2.1-t1.1",
"type": "affects",
"arg1_id": "DerAnaesthesist.90480900.eng.abstr-s7-t2",
"arg2_id": "DerAnaesthesist.90480900.eng.abstr-s7-t1",
"normalized": []
}
] |
DerChirurg.00710001.eng.abstr
|
DerChirurg.00710001.eng.abstr
|
[
{
"id": "DerChirurg.00710001.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Echinococcus multilocularis , a small tapeworm in foxes , has gained considerable public attention owing to its wide distribution in central Europe . Conversely , diagnosis and treatment of the disease have been significantly improved in recent years . Consequently , the incidence among human populations has remained stable and relatively low for many decades . In southern Germany , France ( Franche Comté and Doubs ) , Austria and Switzerland , the annual incidence ranges between 0.02 and 1.4 new cases per 100,000 inhabitants . The relevance of human AE refers to the high lethality of the untreated disease . Therapy consists predominantly of radical surgery followed by continuous , long-term chemotherapy using albendazole ( or mebendazole ) . The action of chemotherapy alone is parasitostatic rather than parasitocidal ; nevertheless , clinical improvement is observed in > 80 % of such cases , including a significantly improved prognosis . Diagnosis relies predominantly on imaging procedures and serology . Immunodiagnosis must be performed early , especially when a preclinical diagnosis is desired upon exposure to infection . Thus , in the framework of seroepidemiological studies , first-time evidence was obtained about the phenomenon of natural resistance in non-diseased persons . This raised the question of a potential immunogenetic predisposition in certain infected persons . E. granulosus ( cystic hydatid disease ) is practically non-existent as autochthonous infection in central Europe now . Most clinical cases of E. granulosus infections are thus observed among persons who have immigrated from - predominantly - the mediterranean basin ."
],
"offsets": [
[
0,
1669
]
]
}
] |
[
{
"id": "DerChirurg.00710001.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"Echinococcus"
],
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[
0,
12
]
],
"normalized": [
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"db_name": "UMLS",
"db_id": "C0013506"
},
{
"db_name": "UMLS",
"db_id": "C0013502"
}
]
},
{
"id": "DerChirurg.00710001.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"tapeworm"
],
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[
38,
46
]
],
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"db_name": "UMLS",
"db_id": "C0007892"
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"db_name": "UMLS",
"db_id": "C0007894"
}
]
},
{
"id": "DerChirurg.00710001.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"foxes"
],
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[
50,
55
]
],
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"db_name": "UMLS",
"db_id": "C0016633"
}
]
},
{
"id": "DerChirurg.00710001.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"attention"
],
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[
89,
98
]
],
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{
"db_name": "UMLS",
"db_id": "C0004268"
}
]
},
{
"id": "DerChirurg.00710001.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"distribution"
],
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[
117,
129
]
],
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"db_name": "UMLS",
"db_id": "C0520511"
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]
},
{
"id": "DerChirurg.00710001.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"Europe"
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141,
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]
},
{
"id": "DerChirurg.00710001.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"diagnosis"
],
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}
]
},
{
"id": "DerChirurg.00710001.eng.abstr-s2-t2",
"type": "umlsterm",
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"treatment"
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]
},
{
"id": "DerChirurg.00710001.eng.abstr-s2-t3",
"type": "umlsterm",
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"disease"
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]
},
{
"id": "DerChirurg.00710001.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"incidence"
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}
]
},
{
"id": "DerChirurg.00710001.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"human"
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},
{
"id": "DerChirurg.00710001.eng.abstr-s3-t3",
"type": "umlsterm",
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"populations"
],
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],
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"db_id": "C0032659"
}
]
},
{
"id": "DerChirurg.00710001.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"Germany"
],
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[
376,
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]
],
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"db_id": "C0017480"
}
]
},
{
"id": "DerChirurg.00710001.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"France"
],
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[
386,
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]
],
"normalized": [
{
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"db_id": "C0016674"
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]
},
{
"id": "DerChirurg.00710001.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"Austria"
],
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423,
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]
],
"normalized": [
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]
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DerChirurg.00710009.eng.abstr
|
DerChirurg.00710009.eng.abstr
|
[
{
"id": "DerChirurg.00710009.eng.abstr-passage-0",
"type": "abstract",
"text": [
"An overview is presented of the various therapy options in cystic and alveolar echinococcosis based on the recent literature and upon personal experience with chemotherapy over the last 20 years . In regions with an optimal surgical infrastructure and relatively small patient cohorts , long-term chemotherapy is practically limited to patients with inoperable echinococcosis , i . e . 10 % cystic and around 70 % alveolar echinococcosis ."
],
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[
0,
439
]
]
}
] |
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"therapy"
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]
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{
"id": "DerChirurg.00710009.eng.abstr-s1-t2",
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] |
[] |
[] |
[
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DerChirurg.00710021.eng.abstr
|
DerChirurg.00710021.eng.abstr
|
[
{
"id": "DerChirurg.00710021.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Hydatid disease , still frequent in endemic areas , is usually localized in the liver . Despite the benign nature of the disease it is one of the problematic fields of surgery due to the high complication rate and long hospital stay . Based on our experience we recommend evacuation of the cyst and omentoplasty as the surgical method of choice , as it is associated with a relatively low incidence of complications and can be performed easily ."
],
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[
0,
445
]
]
}
] |
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"id": "DerChirurg.00710021.eng.abstr-s1-t3",
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"liver"
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80,
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]
},
{
"id": "DerChirurg.00710021.eng.abstr-s1-t4",
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0,
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[] |
[] |
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DerChirurg.00710030.eng.abstr
|
DerChirurg.00710030.eng.abstr
|
[
{
"id": "DerChirurg.00710030.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Inflammatory bowel diseases ( IBD : Crohn's disease , ulcerative colitis ) are chronic inflammatory and frequently relapsing diseases of the gut that ultimately lead to destruction of the intestinal tissue . Recent evidence suggests that a pathologic activation of the mucosal immune system in response to antigens is a key factor in the pathogenesis of IBD . Furthermore , changes in cell migration and cytokine production appear to contribute to the perpetuation of IBD and the postoperative recurrence of Crohn's disease . Based on recent advances in our understanding of the pathogenesis of IBD , several new therapeutic strategies are currently being tested in clinical practice , including recombinant anti-inflammatory cytokines ( IFN- , IL-10, IL-11) and inhibitors of cell adhesion molecules ( ICAM ) , proinflammatory cytokines ( TNF , IL-12) and their receptors ( TNF , IL-6R)."
],
"offsets": [
[
0,
888
]
]
}
] |
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] |
DerChirurg.00710043.eng.abstr
|
DerChirurg.00710043.eng.abstr
|
[
{
"id": "DerChirurg.00710043.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The widespread use of alloplastic materials as the standard procedure for hernia repair makes an evaluation of the long-term integration of these implants imperative . A total of 121 explanted meshes ( mean implantation time 23.2 & 19.7 months ) of polypropylene ( Atrium , n = 20 ; Marlex , n = 50 ; Prolene , n = 21 ) , Polyester ( Mersilene , n = 19 ) and PTFE ( Gore-Tex , n = 11 ) were analyzed in regard to the tissue and cell response within the interface mesh-fiber/tissue . The mesh samples were investigated by light and electronmicroscopy , as well as immunohistochemistry . The morphometric results confirmed a persisting inflammatory proliferative foreign-body reaction with increased cell turnover in the recipient tissues . This reaction is mainly influenced by the selected mesh modification . The consequences of the arising \" chronic wound \" are discussed in detail , in particular with regard to possible malignant transformation ."
],
"offsets": [
[
0,
950
]
]
}
] |
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] |
[] |
[] |
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] |
DerChirurg.00710052.eng.abstr
|
DerChirurg.00710052.eng.abstr
|
[
{
"id": "DerChirurg.00710052.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Objective : The aim of this randomized controlled study was to show whether local anesthesia ( LA ) leads to a decrease of postoperative pain in inguinal hernia repair in comparison with general anesthesia ( AA ) . Method : Sixty volunteer patients were randomly assigned into a LA group and an AA group . All patients had an unilateral primary inguinal hernia and underwent inguinal hernia repair ( Shouldice technique ) . Methods to determine pain were the visual analog scale ( VAS ) , peak flow measurement , the measurement of the FEV1 % , and analgesic consumption . Results : Up to the third postoperative day we measured a decreased pain level in the LA group . The anesthesia procedure was never changed . No essential complications occurred . Conclusion : Therefore , it was concluded that local anesthesia has more advantages than general anesthesia ."
],
"offsets": [
[
0,
862
]
]
}
] |
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"id": "DerChirurg.00710052.eng.abstr-s1-t10",
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"arg1_id": "DerChirurg.00710052.eng.abstr-s4-t9",
"arg2_id": "DerChirurg.00710052.eng.abstr-s4-t5",
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},
{
"id": "DerChirurg.00710052.eng.abstr-s6-r1-t2.1-t1.1",
"type": "conceptual_part_of",
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}
] |
DerChirurg.00710058.eng.abstr
|
DerChirurg.00710058.eng.abstr
|
[
{
"id": "DerChirurg.00710058.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Introduction : The extremely rare but life-threatening hypercalcemic crisis is caused by an exacerbation of a chronic hyperparathyroidism . The etiologic reasons for this exacerbation are conditions which increase the serum calcium level in addition to the hyperparathyroidism with a complete breakdown of the calcium homeostasis , e . g . malignant tumors , primary and tertiary hyperparathyroidism , vitamin D poisoning or overdoses of calcium , vitamin D and calcium-containing ionizer in patients with renal insufficiency . Methods : We present the clinical course of five patients with an acute hypercalcemic crisis and discuss the diagnostic procedure and the principles of surgical treatment with regard to the current literature . Results : A hypercalcemic crisis develops if the total serum calcium concentration is over 4 mmol/l and parathormone over 90 pmol/l . The resulting syndrome is manifested by nausea and vomiting , polyuria and consecutive dehydration and hypotonia culminating in lethargy , hallucinations and coma . Hypercalcemia is the single most important diagnostic finding . Conclusion : The emergency therapy predominantly consists on the one hand in rehydration and parallel stimulation of diuresis . Urgent surgery is required if conservative therapy is not successful ."
],
"offsets": [
[
0,
1300
]
]
}
] |
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"id": "DerChirurg.00710058.eng.abstr-s2-t1",
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{
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{
"id": "DerChirurg.00710058.eng.abstr-s4-t6",
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]
}
] |
[] |
[] |
[
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{
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DerChirurg.00710063.eng.abstr
|
DerChirurg.00710063.eng.abstr
|
[
{
"id": "DerChirurg.00710063.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In the method described by Ciaglia et al. , the trachea is cannulated transcutaneously below the cricoid cartilage under bronchoscopic observation . For this purpose , a Seldinger wire with seven graduated dilatators is used for successive tracheal dilatation to 36 CH and insertion of an indwelling tracheal cannula . The disadvantage of this procedure is the time-consuming successive insertion of seven bougies and the repeated risk of injury to the dorsal tracheal wall . Percutaneous cannulization sets are expensive and cannot be re-sterilized . We developed a re-sterilizable , single-step bougienage device and tested the procedure successfully without any complications in 74 patients ."
],
"offsets": [
[
0,
695
]
]
}
] |
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{
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}
] |
[] |
[] |
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] |
DerChirurg.00710066.eng.abstr
|
DerChirurg.00710066.eng.abstr
|
[
{
"id": "DerChirurg.00710066.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Introduction : About 90 % of the patients have abdominal surgery develop adhesions afterward . Studies analyzing complications and follow-up even in emergency cases are rare . Methods : Intra- and postoperative findings and complications and follow-up were analyzed in a prospective trial between January 1994 and June 1998. Results : We performed laparoscopic procedures in 56 patients with complaints of obstructing adhesive bands or adhesions . Ninety-six percent of the patients have had abdominal surgery ; 51.8 % were treated as emergency cases with acute pain , 48.2 % with chronic abdominal pain . Intraoperatively , 37.5 % of the patients showed single adhesive bands ; 62.5 % showed adhesions . Mean operation time was 60 min , conversion rate : 5.4 % . Complications were recorded according to the \" Cologne classification \" : class I : 78.6 % , class II : 8.9 % , class III : 1.8 % , class IV : 10.8 % , class V : 0 % . The postoperative hospital stay was 6 days on average . Conclusion : Our study suggests that laparoscopic adhesiolysis can be done safely in emergency cases and in patients with extensive adhesions as well ."
],
"offsets": [
[
0,
1139
]
]
}
] |
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] |
[] |
[] |
[
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"id": "DerChirurg.00710066.eng.abstr-s3-r14-t3.1-t9.1",
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{
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DerChirurg.00710080.eng.abstr
|
DerChirurg.00710080.eng.abstr
|
[
{
"id": "DerChirurg.00710080.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Introduction : Diagnosis of extraluminal recurrent rectal cancer may be difficult . Currently the diagnosis is based on routine imaging procedures . Diagnosis often remains unverified until histological proof can be acquired by transcutaneous biopsy or operative exploration . The diagnostic value of positron emission tomography ( PET ) in recurrent rectal cancer was evaluated in a prospective study at the Department of Surgery of the RWTH Aachen University Hospital . The aim of the study was to assess the sensitivity of PET in the detection of recurrent rectal cancer in comparison with conventional procedures . Furthermore , the valency of PET in the diagnosis of the local expansion and metastasis was evaluated . Methods : Since June 1997 , PET has been performed in all patients with suspected recurrent rectal cancer . The examined area reaches from the neck to the symphysis . Visual assessment follows transversal , frontal and sagittal sector scans . Enhanced focal FDG uptake over the physiological enrichment of the environment ( e.g. , urinary tract ) was defined as a criterion of malignancy . The findings were compared with the results of routine diagnosis and histological examinations . Results : Up to now , 23 patients have been subjected to a PET examination . In 17 cases , a local recurrence could be proved . An intrahepatic metastasis was found in 11 patients , pulmonary metastasis in 3 patients , lymph-node metastasis in 5 patients , and a peritoneal carcinomatosis was found in 4 patients . All these findings were confirmed by histological examinations after biopsy and operation or by other imaging procedures and the clinical follow-up . Conclusions : The controlled results show that PET can detect recurrent rectal cancer and its metastasis with great precision . PET seems to be a useful additional examination in the diagnosis of extraluminal recurrent rectal cancer ."
],
"offsets": [
[
0,
1909
]
]
}
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DerChirurg.00710089.eng.abstr
|
DerChirurg.00710089.eng.abstr
|
[
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"text": [
"Deciduosis of the appendix is a rare cause of acute appendicitis in pregnancy . Ectopic decidual cells localized in the submesothelial stroma may represent a physiologic reaction of the pluripotent stromal cells to progestational hormonal stimulation . Less frequently , deciduosis is based on a preexisting extragenital endometriosis , visible in a localization other than strictly submesothelial , in residuals of cyclic proliferation and bleeding , and in endometrial glandular formations embedded in the decidual cells ."
],
"offsets": [
[
0,
524
]
]
}
] |
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] |
[] |
[] |
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] |
DerChirurg.00710093.eng.abstr
|
DerChirurg.00710093.eng.abstr
|
[
{
"id": "DerChirurg.00710093.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Introduction : Abdominal actinomycosis is an uncommon disease . Nevertheless it should be considered in case of unclear tumor-like abdominal masses . Methods : We report a case of a 49-year-old patient with an intrauterine device . The patient was submitted with a solid and painful tumor in the upper abdomen . After sonography , computerized tomography , gastroduodenoscopy and colonoscopy the preoperative presumptive diagnosis was a carcinoma of the transvers colon invading the abdominal wall . Pathological examination after a right hemicolectomy surprisingly revealed an actinomycosis . Results : Based on this case diagnostic tools and therapeutic options of actinomycosis of the colon are discussed . Conclusions : This case illustrates the importance to consider the possibility of actinomycosis when finding an unclear abdominal mass . After a surgical excision an abdominal actinomycosis requires antibiotic therapy ."
],
"offsets": [
[
0,
929
]
]
}
] |
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"id": "DerChirurg.00710093.eng.abstr-s4-t3",
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}
] |
[] |
[] |
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DerChirurg.00710098.eng.abstr
|
DerChirurg.00710098.eng.abstr
|
[
{
"id": "DerChirurg.00710098.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A case report demonstrates the complication of pericardial tamponade during the installation of a central venous catheter via the subclavian vein . To reduce the high mortality of this rare complication , quickly applicable diagnostic measures and adequate therapy of pericardiocentesis are indicated . Prompt recognition and treatment of pericardial tamponade are imperative if a disastrous outcome is to be prevented ."
],
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0,
420
]
]
}
] |
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{
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],
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31,
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]
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"db_id": "C0009566"
}
]
},
{
"id": "DerChirurg.00710098.eng.abstr-s1-t2",
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],
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113,
121
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}
]
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{
"id": "DerChirurg.00710098.eng.abstr-s1-t3",
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"vein"
],
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]
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}
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"id": "DerChirurg.00710098.eng.abstr-s1-t4",
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2,
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]
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}
]
},
{
"id": "DerChirurg.00710098.eng.abstr-s1-t5",
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"pericardial tamponade"
],
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47,
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{
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130,
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}
]
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{
"id": "DerChirurg.00710098.eng.abstr-s2-t6",
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},
{
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],
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}
]
}
] |
[] |
[] |
[
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},
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},
{
"id": "DerChirurg.00710098.eng.abstr-s1-r5-t2.1-t1.1",
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{
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{
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},
{
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},
{
"id": "DerChirurg.00710098.eng.abstr-s2-r1-t4.1-t5.1",
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"id": "DerChirurg.00710098.eng.abstr-s2-r3-t1.1-t2.1",
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"id": "DerChirurg.00710098.eng.abstr-s2-r6-t5.1-t2.1",
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},
{
"id": "DerChirurg.00710098.eng.abstr-s2-r7-t4.1-t2.1",
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},
{
"id": "DerChirurg.00710098.eng.abstr-s3-r1-t2.1-t1.1",
"type": "result_of",
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},
{
"id": "DerChirurg.00710098.eng.abstr-s3-r2-t1.1-t2.1",
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"arg2_id": "DerChirurg.00710098.eng.abstr-s3-t2",
"normalized": []
},
{
"id": "DerChirurg.00710098.eng.abstr-s3-r3-t2.2-t1.1",
"type": "result_of",
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"id": "DerChirurg.00710098.eng.abstr-s3-r4-t2.1-t1.1",
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"arg2_id": "DerChirurg.00710098.eng.abstr-s3-t1",
"normalized": []
}
] |
DerChirurg.00710101.eng.abstr
|
DerChirurg.00710101.eng.abstr
|
[
{
"id": "DerChirurg.00710101.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Introduction : Undifferentiated , embryonal sarcoma is a rare malignant tumour of the liver , the incidence of which is highest in children between 6 and 10 years of age ( 14.1 % ) . Among the primary tumours of the liver in childhood it ranks in third place after hepatocellular carcinoma and focal nodular hyperplasia . Embryonal sarcoma is much rarer in adults . To our knowledge , only 18 cases have been published in the last 50 years . Methods and results : We now present the case of a 29-year-old woman with spontaneous rupture of the liver caused by an undifferentiated sarcoma . Conclusion : This case report illustrates the possibility of an embryonal sarcoma being the reason for spontaneous rupture of the liver . The management of this case comprised primary tamponade , interventional embolisation of the feeding artery , and secondary resection under stable conditions ."
],
"offsets": [
[
0,
886
]
]
}
] |
[
{
"id": "DerChirurg.00710101.eng.abstr-s1-t1",
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],
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{
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}
]
},
{
"id": "DerChirurg.00710101.eng.abstr-s1-t3",
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},
{
"id": "DerChirurg.00710101.eng.abstr-s1-t4",
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},
{
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}
]
},
{
"id": "DerChirurg.00710101.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
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]
},
{
"id": "DerChirurg.00710101.eng.abstr-s1-t7",
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]
},
{
"id": "DerChirurg.00710101.eng.abstr-s1-t8",
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62,
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}
]
},
{
"id": "DerChirurg.00710101.eng.abstr-s2-t1",
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201,
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{
"id": "DerChirurg.00710101.eng.abstr-s2-t2",
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]
},
{
"id": "DerChirurg.00710101.eng.abstr-s2-t3",
"type": "umlsterm",
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"db_id": "C0007097"
}
]
},
{
"id": "DerChirurg.00710101.eng.abstr-s2-t4",
"type": "umlsterm",
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"hyperplasia"
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]
},
{
"id": "DerChirurg.00710101.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"hepatocellular carcinoma"
],
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265,
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],
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"db_id": "C0019204"
}
]
},
{
"id": "DerChirurg.00710101.eng.abstr-s2-t6",
"type": "umlsterm",
"text": [
"focal nodular hyperplasia"
],
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[
294,
319
]
],
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{
"db_name": "UMLS",
"db_id": "C0333980"
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[] |
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DerChirurg.00710106.eng.abstr
|
DerChirurg.00710106.eng.abstr
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{
"id": "DerChirurg.00710106.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The academic title \" Privatdozent \" , unique to the German speaking countries , is awarded after the \" Habilitation \" , a qualification to teach and perform research on a high level and independent of supervision by a professor . A few years after the \" Habilitation \" , committees of medical faculties decide whether the title \" ausserplanmaessiger Professor \" can be awarded . This is an academic title independent of a specific university or extramural position . The rules of all German medical faculties were evaluated with regard to when and by what criteria the faculties decide . There were major differences , e . g . the minimum time after the \" Habilitation \" ( 4 years n = 9 ; 5 years n = 14 ; 6 years n = 7 ) , the numbers and quality of published papers and abstracts , the amount and quality of teaching and the number and qualification of external reviewers . For applications for university positions , but even more for leading positions in hospitals and industry , the title of \" apl . Prof. \" is still of major relevance . Therefore a certain degree of standardization but still leaving space for special criteria in different faculties , is proposed ."
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] |
[] |
[] |
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"id": "DerChirurg.00710106.eng.abstr-s1-r1-t1.1-t3.1",
"type": "isa",
"arg1_id": "DerChirurg.00710106.eng.abstr-s10-t1",
"arg2_id": "DerChirurg.00710106.eng.abstr-s10-t3",
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},
{
"id": "DerChirurg.00710106.eng.abstr-s2-r1-t3.1-t1.1",
"type": "performs",
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},
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},
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},
{
"id": "DerChirurg.00710106.eng.abstr-s8-r2-t2.1-t3.1",
"type": "carries_out",
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"arg2_id": "DerChirurg.00710106.eng.abstr-s10-t3",
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},
{
"id": "DerChirurg.00710106.eng.abstr-s8-r3-t1.1-t3.1",
"type": "carries_out",
"arg1_id": "DerChirurg.00710106.eng.abstr-s10-t1",
"arg2_id": "DerChirurg.00710106.eng.abstr-s10-t3",
"normalized": []
},
{
"id": "DerChirurg.00710106.eng.abstr-s10-r1-t2.1-t1.1",
"type": "evaluation_of",
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"arg2_id": "DerChirurg.00710106.eng.abstr-s10-t1",
"normalized": []
}
] |
DerChirurg.00710109.eng.abstr
|
DerChirurg.00710109.eng.abstr
|
[
{
"id": "DerChirurg.00710109.eng.abstr-passage-0",
"type": "abstract",
"text": [
"On the basis of the claims data of the statutory health insurance funds , surgery rates and small-area variations within the catchment area of the AOK Magdeburg were examined for the year 1997. Substantial variation can be constantly seen . The extremal quotient at the 30 most frequent ICPM groups ranged from 2 to 5. Generally , the extent of the variation was larger with elective procedures than with acute . Correlation analyses do not show clear associations with hospital bed supply and physician density in primary sectors . The extent of the small-area variation requires further research to evaluate possible determinants of surgery rates . Criteria for hospital admission and indications for surgery should be made explicit ."
],
"offsets": [
[
0,
736
]
]
}
] |
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"health"
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}
]
},
{
"id": "DerChirurg.00710109.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
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}
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},
{
"id": "DerChirurg.00710109.eng.abstr-s1-t3",
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"text": [
"funds"
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DerChirurg.00710129.eng.abstr
|
DerChirurg.00710129.eng.abstr
|
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"Abstract . The widely propagated morbidity and mortality risks of obesity appear somewhat exaggerated , except for morbid obesity ( BMI > 40 kg/m2) and for high-risk obese subgroups concerning diabetes mellitus , hypertension , metabolic syndrome and obstructive sleep apnea syndrome . Non-medical reasons represent a major component of the social pressure that is presently experienced by obese persons in our society . Weight reduction represents the primary therapeutic approach in overweight patients with type 2 diabetes , hypertension , metabolic syndrome and obstructive sleep apnea , and it may be recommended in high-risk individuals for primary prevention of these diseases . Massive obesity is associated with excess mortality , especially in younger , physically inactive men with upper-body-segment obesity . It is widely assumed that weight reduction will lead to a reduction of excess mortality in these individuals ; so far , however , there is no proof for this assumption . Non-medicamentous conservative therapeutic approaches to weight reduction have the advantage of safety , even though their long-term efficacy is generally disappointing . There are no randomized , controlled trials to prove a reduction of morbidity or mortality risks and of therapeutic safety for pharmacological , invasive or surgical methods to treat obesity ."
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] |
[] |
[] |
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] |
DerChirurg.00710134.eng.abstr
|
DerChirurg.00710134.eng.abstr
|
[
{
"id": "DerChirurg.00710134.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Abstract . The jejunoileostomy was a frequently used surgical procedure to treat morbid obese patients ( obesity grade III ) from 1970 to 1980. The observed weight loss was very good , 50-60 kg during the first 18 months after operation ( n = 288 ) . Even obesity-induced side effects were improved significantly . However , negativ consequences and complications were seen all too often : chronic loss of electrolytes , protein and vitamins and diarrhea with perianal skin problems . Reoperations were often necessary due to renal stone formation , cholecystolithiasis or blind loop syndrome . Therefore this procedure was abandoned in favor of operations such as vertical banded gastroplasty or the adjustable gastric band . However , in special cases similar operations may be helpful if gastric restriction has failed ."
],
"offsets": [
[
0,
823
]
]
}
] |
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[] |
[] |
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DerChirurg.00710159.eng.abstr
|
DerChirurg.00710159.eng.abstr
|
[
{
"id": "DerChirurg.00710159.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Abstract . In vitro functions of stimulated peripheral T cells and monocytes were investigated in patients experiencing sepsis following major visceral surgery . Cell culture supernatants were analyzed by ELISA for IL-2, IFN- , IL-4, IL-10, TNF- , IL-1, and IL-12 p40. In addition , monocyte HLA class II expression was determined by flow cytometry . T cell secretion of IL-2, TNF- , and in part IFN- ( but not IL-4) was significantly diminished in non-survivors throughout the entire course of sepsis , compared to controls and sepsis survivors . Production of IL-1 and IL-12 p40 by monocytes was strongly reduced in both survivors and non-survivors at the onset of sepsis . Persistence of depressed monocyte cytokine secretion correlated with lethality . Thus , overall suppression of cytokine production by T cells and monocytes was already observed at the beginning of postoperative sepsis . HLA class II expression by monocytes exhibited a strong and sustained down-regulation with no significant differences between sepsis survivors and non-survivors . In summary , suppression of both T cell and monocyte functions develops early during postoperative sepsis . Recovery of immune functions and severity of immune defects are associated with outcome ."
],
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] |
DerChirurg.00710166.eng.abstr
|
DerChirurg.00710166.eng.abstr
|
[
{
"id": "DerChirurg.00710166.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Abstract . Iatrogenic bile duct lesions are serious complications during laparoscopic cholecystectomy and include biliary leakage and major bile duct injury . The incidence of biliary lesions following laparoscopic cholecystectomy is up to threefold higher than that of the open procedure . A total of 108 patients with bile duct lesions after laparoscopic cholecystectomy were treated at our institution . Endoscopic treatment was successful in 68 cases , 6 patients were treated by external drainage , and 34 patients required surgical therapy . Selection criteria for the type of treatment included the etiology , anatomical situation , and diagnostic interval of the biliary lesion . We suggest a classification of bile duct injury and a proposal for diagnosis and treatment of these complications ."
],
"offsets": [
[
0,
803
]
]
}
] |
[
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"Abstract"
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8
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]
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{
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"text": [
"bile"
],
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[
22,
26
]
],
"normalized": [
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"db_id": "C0005388"
}
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},
{
"id": "DerChirurg.00710166.eng.abstr-s2-t2",
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],
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[
52,
65
]
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{
"id": "DerChirurg.00710166.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"cholecystectomy"
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86,
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],
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DerChirurg.00710174.eng.abstr
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DerChirurg.00710174.eng.abstr
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"Abstract . Introduction : Bile duct complications after laparoscopic cholecystectomy occur twice to three times more frequently than after an open procedure . Four different types of lesions may be differentiated by the Siewert classification : postoperative bile fistulas ( type I ) , late strictures ( type II ) , tangential injuries of the bile duct ( type III ) and defect lesions ( type IV ) . The diagnostic and therapeutic management is demonstrated in relation to our own experience and the literature . Methods : Eleven patients ( median age 43.8 +/- 17.2 ) with bile duct complications after laparoscopic cholecystectomy were operatively treated between November 1993 and December 1998. Nine patients ( four type-II lesions , five type-IV lesions ) were referred from another hospital ; 2 defect lesions out of 410 laparoscopic cholecystectomies ( 0.5 % ) were documented in our own patient group . Results : Four patients with late strictures were operatively treated with a hepaticocholedochostomy ( n = 2 ) or hepaticojejunostomy ( n = 2 ) after 14.3 +/- 8.4 months and were discharged from hospital after 10.6 +/- 3.8 days . In both cases with type-IV lesion and a short defect , an end-to-end anastomosis was successful ( hospital stay 11.6 +/- 1.0 days ) . However , a retrocolic Roux-Y end-to-side hepaticojejunostomy was perfomed in all cases with a larger defect ( n = 5 ; hospital stay 14.8 +/- 2.0 days ) . The two defect lesions in our own group were detected by intraoperative cholangiography and immediately treated after conversion either with hepaticocholedocho-stomy or hepaticojejunostomy ( hospital stay 11.2 +/- 0.6 days ) . Conclusions : The incidence of bile duct complications after laparoscopic cholecystectomy might be kept down by anatomic preparation , selective intraoperative cholangiography and early consideration of conversion to open procedure . The clinical course after biliary tract injury can be positively influenced only by a standard diagnostic and operative procedure and by an early transfer to a specialized center ."
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[] |
[] |
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DerChirurg.00710182.eng.abstr
|
DerChirurg.00710182.eng.abstr
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"Abstract . Introduction : High benign biliary stenoses , which can occur as a complication of disease or surgery , may be difficult to correct by open surgery and may also carry a high risk . An alternative to surgery is the percutaneous implantation of a flexible metallic stent or silicon prosthesis at the affected site . Methods : Twelve patients with benign biliary stenoses have been operated on in our department since March 1992 , and the therapeutic success was reviewed in this study . Results : Six received a Palmaz stent and six a silicon prosthesis , with a follow-up after completion of treatment of more than 7 years and more than 3 years , respectively . Fifty percent of the patients with a stent experienced no problems and 66 % of the stents remained patent ( including one requiring operative intervention to restore patency ) . No further surgery was necessary in any of the patients with a silicon prosthesis . Conclusion : When the advantages and disadvantages of the various procedures are considered , long-term splinting with a wide-lumened silicon prosthesis ( Yamakava ) appears to be a promising alternative to surgery for the treatment of benign biliary stenosis ."
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DerChirurg.00710189.eng.abstr
|
DerChirurg.00710189.eng.abstr
|
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{
"id": "DerChirurg.00710189.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Abstract . Introduction : To compare treatment results an international established classification is necessary . In 1997 the TNM classification of 1992 was modified . Methods : Between 1983 and 1997 , 159 patients with a ductal carcinoma of the pancreas underwent resection . All data of the resected specimens were documented in standardized manner prospectively in a protocol that offered ready transfer of the collected data to a new classification . The TNM categories and stage groupings were transferred to the new UICC classification of 1997 and analyzed in comparison to the classification of 1992. Results : The inclusion of a pT4 category equivalent to the other GI tumors made a new stage grouping necessary . Also division into pN1 a and pN1 b was established . According to the clinical experience only few tumors in early stages ( pT1/2 and stage I ) were observed in the new classification . There was a significant improval in the patient's distribution to the new stage grouping because of the homogeneous groups . In comparison to the 1992 classification the new stage II shows a relevant prognostic value and a significant difference to stage III . Conclusion : We conclude that the new UICC classification relates to prognosis better than the old classification ."
],
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1284
]
]
}
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"id": "DerChirurg.00710189.eng.abstr-s4-t3",
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{
"id": "DerChirurg.00710189.eng.abstr-s4-t5",
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[] |
[] |
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DerChirurg.00710196.eng.abstr
|
DerChirurg.00710196.eng.abstr
|
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{
"id": "DerChirurg.00710196.eng.abstr-passage-0",
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"text": [
"Abstract . Introduction : The most common benign ampullary tumors are adenomas ( 80 % ) . They are considered as premalignant lesions with a transformation rate to carcinoma of up to 30 % . Methods : From 1 January 1997 to 28 February 1999 we treated 11 patients with adenoma of the ampulla of Vater . An ampullectomy was performed in 10 cases . One poor-risk patient could not be operated on . Results : No operative mortality occurred . In two patients a pT1 adenocarcinoma was diagnosed postoperatively . One of the two patients with a high-risk carcinoma underwent a second operation , a Whipple pancreatoduodenectomy . Nine of 10 patients had no recurrence with a median follow-up of 12 months . Conclusion : One patient died of glioblastoma . We would therefore recommend ampullectomy as the first-line treatment for benign tumors of the ampulla of Vater . In low-risk pT1 carcinoma ( G1/G2, L0) and R0 resection , local excision is acceptable . In high-risk pT1 carcinoma ( G3 and/or L1) Whipple pancreatoduodenectomy is mandatory ."
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DerChirurg.00710202.eng.abstr
|
DerChirurg.00710202.eng.abstr
|
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"id": "DerChirurg.00710202.eng.abstr-passage-0",
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"Abstract . Introduction : The aim of the study was to evaluate the modern principles of surgery in diverticulitis , e . g . early elective resection and primary anastomosis . Methods : The data of 445 consecutive patients were retrospectively analysed after classifying all cases in four subgroups according to a modified Hinchey classification ( stages 0-III ) . Results : Within our study group the morbidity was 26.5 % ( n = 118 ) and the mortality was 1.6 % ( n = 7 ) . In 96 % ( n = 425 ) of all cases and in 64 % ( 21/33 ) of patients with perforated diverticulitis and peritonitis ( stage III ) , a primary anastomosis was performed . Four patients of the study group showed insufficient anastomosis ( 0.9 % ) . No leakage was observed from any of the anastomoses performed in stage III diverticulitis . Stage of inflammation and age of patient correlate with morbidity and mortality . Some 53 % ( 94/177 ) of the patients in stage II and 67 % ( 22/33 ) of the patients in stage III had never showed symptoms of diverticulitis before . Conclusion : Prophylactic surgery to avoid life-threatening situations , including abscess formation or perforation , is not possible in many cases . However , especially patients at risk ( age , coexisting illness ) should undergo early surgery . Primary anastomosis can be performed safely even at an advanced stage ."
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DerChirurg.00710209.eng.abstr
|
DerChirurg.00710209.eng.abstr
|
[
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"id": "DerChirurg.00710209.eng.abstr-passage-0",
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"Abstract . Aim of the study : About 30 % of the patients with acute aortic dissection suffer from organ or limb ischemia . We analyzed the influence of ischemic localization and method of operative treatment ( aortic fenestration or extraanatomic bypass revascularization ) on morbidity and mortality . Patients and methods : From 1 May 1987 to 31 December 1998 21 patients with 24 vascular complications such as renal or intestinal ischemia , lower extremity ischemia and paraplegia following acute aortic dissection were treated at our institution . Recruitment was retrospective in 16 and prospective in 5 patients . In 5 patients ( 24 % ) the complication was associated with Stanford A , in 16 ( 76 % ) with Stanford B dissection . Ten patients ( 48 % ) complained of malperfusion of only one region , whereas 11 patients ( 52 % ) suffered from ischemia of two or three different regions . Aortic fenestration and resection of the dissected membrane was performed in nine cases ( 37 % ) . Fifteen patients ( 63 % ) were treated with extraanatomic bypass techniques . Results : One third of the patients died , four of them due to aortic penetration or perforation and two due to visceral ischemia . During follow-up of 32 ( 1-110 ) months two patients developed aortic complications . One died of aortic perforation , while the other developed a thoracoabdominal aneurysm and had to be treated by a tube graft replacement . Conclusions : Outcome depended more on the spontaneous course of aortic dissection and on prompt diagnosis and therapy of the complications than on the different operative techniques ."
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[] |
[] |
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DerChirurg.00710215.eng.abstr
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DerChirurg.00710215.eng.abstr
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"Abstract . Introduction : Postoperative delirium is a common psychic disturbance occurring acutely after various surgical procedures and typically presenting with a fluctuating course . These patients ' recovery takes longer . In this study we analyze the incidence of postoperative delirium in patients undergoing vascular surgery and try to identify risk factors for its development . Methods : Patients undergoing elective arterial operations were included . Their medical history , the specific vascular diagnosis and operation performed , the medication and laboratory data were monitored . Additionally the patients were preoperatively interviewed by a psychiatrist . Intraoperatively the drugs , infusions , possible transfusions , blood gases and pressures were monitored , as were the times of surgery and anesthesia . Postoperatively patients were seen daily by the psychiatrist and the surgeon for at least 7 days . Postoperative delirium was diagnosed according to DSM IV criteria , and mild , moderate and severe delirium were distinguished . Results : Fifty-four patients entered the study . Twenty-one ( 38.9 % ) developed postoperative delirium ( 11 mild , 2 moderate , 8 severe ) . Patients with aortic operations developed delirium more frequently than those with non-aortic procedures ( 55.5 vs 22.2 % , n = 27 each ) . Some preexisting diseases ( hearing disturbance ) increased the probability of postoperative delirium , while age was not identified as a risk factor . General psychopathological and depressive disturbances increased the likelihood of postoperative delirium . Patients who had a severe intraoperative course developed postoperative delirium more frequently . This was not seen in the absolute time of surgery or anesthesia nor in the intraoperative development of blood pressure or intraarterial gases , which did not differ between patients with and without postoperative delirium . More reliable parameters were an increased intraoperative need for crystalloid volume , intra - or postoperatively decreased hemoglobin values ( Hb 10 g/dl ) and the development of acidosis that had to be treated . Patients with delirium had serious complications more often ( 8/21 = 38.1 % vs 6/33 = 18.2 % ) and needed Intensive Care treatment longer ( 2.7 vs 2.1 days , only aortic surgery 3.2 vs 2.4 days ) . Conclusions : Postoperative delirium after vascular surgery is frequent . Patients undergoing aortic surgery , with specific concomittant medical disease , psychopathological disturbances and a severe intraoperative course , are at risk of developing postoperative delirium ."
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[] |
[] |
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DerChirurg.00710228.eng.abstr
|
DerChirurg.00710228.eng.abstr
|
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"Abstract . Abdominal organs such as the rectum and urinary bladder are rarely involved in Klippel-Trénaunay syndrome , but may occasionally be the source of severe blood loss . Since frequently no isolated source of bleeding is identified , severe blood loss can result in a critical condition . This article describes an unusual multimodal treatment concept for a patient with Klippel-Trénaunay syndrome associated with severe recurrent rectal bleeding . We present the case of a 39-year-old patient with Klippel-Trénaunay syndrome and a history of rectal bleeding since childhood requiring multiple blood transfusions over the years . He was referred to our department in a state of continuous rectal bleeding . Preoperative work-up revealed a complete alteration of the rectum and the distal parts of the sigmoid/colon by hemangiomas , with diffuse bleeding from the destroyed rectal mucosa . Preoperatively the superior rectal artery was embolized . After a 48-h interval , sphincter-preserving complete rectal excision including the sigmoid/colon was performed followed by a colon pouch anal anastomosis and protective loop ileostomy ."
],
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[] |
[] |
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] |
DerChirurg.00710234.eng.abstr
|
DerChirurg.00710234.eng.abstr
|
[
{
"id": "DerChirurg.00710234.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Abstract . Usually postoperative wounds are kept dry until the stitches are removed . In a prospective randomized study early water contact was allowed in order to test postoperative wound healing in 817 patients operated on for varicose veins . Regardless of whether the wounds were kept dry or had water contact with or without shower foam from the second postoperative day , no infection was registered ."
],
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[
0,
407
]
]
}
] |
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"id": "DerChirurg.00710234.eng.abstr-s4-t2",
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"id": "DerChirurg.00710234.eng.abstr-s4-t5",
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] |
[] |
[] |
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DerChirurg.00710249.eng.abstr
|
DerChirurg.00710249.eng.abstr
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"Abstract . It is difficult to provide valid data with regard to changes in incidence and prevalence of acute pancreatitis in Germany . The lack of information is due to strict legal regulations to protect personal data , a certain lack of interest in epidemiological research and the lack of exact statistics of diseases treated in hospitals . The incidence of acute pancreatitis in other industrialized Western countries is about 10 new cases per year and 100,000 inhabitants . The increase of alcohol consumption over the last 30 years is associated with an increase of ethanol-induced pancreatitis . One may speculate that due to improved diagnostic possibilities , such as CT scan , cases where acute pancreatitis is diagnosed at autopsy are rare . Due to the increase in alcohol consumption it can be assume that the incidence and prevalence of chronic pancreatitis have increased in Germany similar to well-documented data from Denmark . Since alcohol consumption is slightly decreasing in Germany it is likely that the present incidence of about 10 cases of chronic pancreatitis per 100,000 inhabitants will also decrease ."
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[] |
[] |
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] |
DerChirurg.00710253.eng.abstr
|
DerChirurg.00710253.eng.abstr
|
[
{
"id": "DerChirurg.00710253.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Abstract . Induction of acute pancreatitis follows a uniform mechanism independent of the different etiologic factors such as gallstones , alcohol , ischemia , hyperlipidemia , hypercalcemia , hereditary and others . Each cause seems to affect primarily the acinar cell , resulting in premature intracellular activation of trypsinogen and other digestive enzymes . Activated enzymes and oxygen free radicals injure the acinar cell and cause a release of cytokines and vasoactive mediators , attract inflammatory cells and activate the vascular endothelium as well as the expression of adhesion molecules . The disturbance of the pancreatic microcirculation induces a progression from edematous to necrotizing pancreatitis independent of the early intracellular events , including protease activation . Specific therapy must be directed towards microperfusion failure as a secondary pathogenetic step , since the initial enzyme activation and cytokine release is irreversible by the time of clinical presentation . In experimental designs comparable to the clinical situation the following therapeutic principles have proven beneficial : increase of blood fluidity by dextran , inhibition of leukocyte-endothelium interaction by ICAM-1 antibodies , and blockade of local vasoconstriction by endothelin-receptor antagonists ."
],
"offsets": [
[
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DerChirurg.00710265.eng.abstr
|
DerChirurg.00710265.eng.abstr
|
[
{
"id": "DerChirurg.00710265.eng.abstr-passage-0",
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"text": [
"Abstract . Early endoscopic intervention is required in the treatment of biliary pancreatitis in the presence of cholangitis or jaundice , possibly with dilated common bile duct . Also patients with predicted severe disease , lack of spontaneous clinical improvement or progressive jaundice might benefit from endoscopic retrograde cholangiopancreatography ( ERCP ) with sphincterotomy . If endoscopy is indicated , it should be performed as soon as possible . Injection of contrast medium into a dilated bile duct is accompanied by the risk of cholangitis . Therefore therapeutic decompression by sphincterotomy and stone extraction is necessary , or , if this is not possible , insertion of a naso-biliary tube for drainage . Prophylactic use of antibiotics is recommended periinterventionally . Early endoscopic intervention is not necessary in patients with mild biliary pancreatitis and spontaneous clinical improvement . Here , ERCP can be performed later , if indicated ."
],
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DerChirurg.00710269.eng.abstr
|
DerChirurg.00710269.eng.abstr
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"Abstract . In the present review we describe our experience with debridement in necrotizing pancreatitis , with particular emphasis on the indications for surgery and the outcome in patients with infected and sterile necrosis . Within 7 years 64 patients with necrotizing pancreatitis underwent surgery with a median preoperative APACHE II score of 9. The indications for surgery were either proven infection or persistence of symptoms . Thirty-six patients were found to have infected necrosis , while 28 patients had sterile necrosis . There was no significant difference between the two groups regarding pre- and postoperative parameters . The surgical technique involved a blunt necrosectomy followed by closed packing with Penrose drains . This technique produced the lowest reported mortality of 6.2 % with a reoperation rate of only 17 % , demonstrating that even with sterile necrosis surgical management can be carried out safely ."
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[] |
[] |
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DerChirurg.00710274.eng.abstr
|
DerChirurg.00710274.eng.abstr
|
[
{
"id": "DerChirurg.00710274.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Necrotizing pancreatitis is still associated with considerable morbidity and mortality . Formerly , surgical treatment with early and extensive pancreatic resection has been the standard . Improvements in our understanding of the pathogenesis of the disease and progress in the field of intensive care therapy have made conservative therapy the initial standard in the treatment of necrotizing pancreatitis . A considerable percentage of patients with sterile necrosis can be managed with low morbidity and mortality by conservative treatment without operation . Nevertheless , surgical treatment is indicated in patients with infected necrosis and in sterile necrosis if multiorgan failure persists over a limited period of time despite maximum intensive care therapy . Pancreatic resection should be abandoned for surgical treatment of pancreatic necrosis , as results with regard to morbidity , mortality and long-term outcome are unsatisfactory . Today the surgical standard is careful digital necrosectomy , which must be followed by either postoperatve drainage , repeated open lavage or continuous closed lavage . In experienced hands , all three procedures provide similar results with regard to morbidity and mortality ."
],
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[
0,
1229
]
]
}
] |
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[] |
[] |
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DerChirurg.00710281.eng.abstr
|
DerChirurg.00710281.eng.abstr
|
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"Abstract . Surgical hospitals can be seen as operational or even industrial production systems . Doctors have a major impact on both medical performance and costs . For active participation in the management process , knowledge of industrial controlling mechanisms is required . German hospitals currently receive no procedure-related financial revenues , such as prices or tariffs for defined medical treatment activities . Maximum clinical revenues are , furthermore , limited by principles of planned economy and can be increased only slightly by greater medical performance . Costs are the only target that can be autonomously influenced by the management . Operative controlling in hospitals aims at horizontal and vertical coordination of subunits and decentralisation of process regulations . Hospital medical performance is not clearly defined , its quantitative measurement very problematic . Process-orientated clinical activities are not taken into account . A high percentage of hospital costs are fixed and can be influenced only by major structural interventions in the long term . Variable costs are primarily dependent on the quantity of clinical activities , but also heavily influenced by patient structure ( comorbidity and risk profile ) . The various forms of industrial cost calculations , such as internal budgeting , internal markets or flexible plan-cost balancing , cannot be directly applied in hospital management . Based on these analyses , current operational concepts and strategic trends are listed to describe cost-management options in hospitals with focus on the German health reforms ."
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[] |
[] |
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DerChirurg.00710300.eng.abstr
|
DerChirurg.00710300.eng.abstr
|
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{
"id": "DerChirurg.00710300.eng.abstr-passage-0",
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"text": [
"Abstract . The aetiology of varicosis is still unclear . Investigation of changes in normal veins which result in the formation of varicosis led to examination of elastic properties and histomorphological alterations in the region of the extracellular matrix in the vessel wall of the long saphenous vein in normal and varicose veins . The rigidity of varicose veins was higher than that of normal veins ; there was no difference between the varicose vein above a competent valve and the \" normal \" vein below this competent valve . The matrix proteins demonstrated an increase in total fibres , whereas the elastic fibres were reduced and fragmented , explained the rigidity of varices . These results suggest that the role of the venous valves in the development of varicose veins is secondary to changes of the vein wall ."
],
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825
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]
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DerChirurg.00710311.eng.abstr
|
DerChirurg.00710311.eng.abstr
|
[
{
"id": "DerChirurg.00710311.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Abstract . Introduction : The treatment of soft tissue defects of the foot and ankle region remains a challenge , because special anatomical and physiological properties have to be considered . Patients and methods : The data of 52 patients , who were treated between 1994 and 1998 , were analyzed . 48 % were posttraumatic defects and were located in the weight bearing zone in 37 % . Results : Fifty-nine procedures were used , including skin transplantation in 16 patients , local flaps in 3 cases , regional flaps in 14 cases , and microvascular procedures in 17 cases . Amputation was required in 4 patients . The overall success rate was 92 % . Complications occurred in 18 patients . Conclusions : Using these data and evaluation of the actual literature lead to the development of an algorithm for the treatment of defects in this area . The modern armamentarium of plastic surgery offers the possible different treatment modalities ."
],
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0,
942
]
]
}
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DerChirurg.00710319.eng.abstr
|
DerChirurg.00710319.eng.abstr
|
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{
"id": "DerChirurg.00710319.eng.abstr-passage-0",
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"text": [
"Abstract . Introduction : The aim of the following article is to summarize our experience in the treatment of osteiod osteomas , with special emphasis on diagnostic and therapeutic pitfalls . Patients and methods : A consecutive series of 14 patients with osteoid osteomas was treated surgically between 1985 and 1996. All tumors but one were located in the lower limb . The main symptom was pain , being worse at night and being responsive to oral salicylates ( 10/14 patients ) . As reported in other studies , the duration of symptoms was unacceptably long ( mean 24 months ) . The classical pathognomonic symptoms were misinterpreted in many cases , leading to frustrating conservative and even operative therapies . Results : Open biopsy prior to surgical excision is not indicated because of the typical clinical and roentgenographic imaging of these lesions . Surgical excision of the nidus is the treatment of choice and gives immediate pain relief . If the characteristic morphology is not evident in plain roentgenograms , conventional tomograms , radionuclide scans and computerized tomography are reliable tools . All patients were free of disease at a mean of 6.6 years after operation . Conclusion : In symptomatic patients with osteoid osteomas the excision of the nidus is the established diagnostic/therapeutic modality . Minimally invasive procedures seem to be alternatives to classical surgery ."
],
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[
0,
1415
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}
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[] |
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DerChirurg.00710326.eng.abstr
|
DerChirurg.00710326.eng.abstr
|
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"Abstract . Dislocated metacarpal V fractures , fixed by percutaneous Kirschner wires or other implants near the metacarpophalangeal joint , often show impaired movement despite excellent radiologic findings . We therefore chose an alternative method using intramedullary Kirschner wire osteosynthesis according to Foucher . Twenty-five patients were operated on in a 3-year period and movement of the fingers and complications were examined . Six weeks after operation all fractures were consolidated in anatomical reduction . One patient suffering from an early stage of Sudeck's dystrophy was healed , and no other complications appeared . Three months after treatment all patients achieved free movement of the fingers with anatomical alignment . We therefore recommend intramedullary Kirschner wire osteosynthesis in distal metacarpal V fractures ."
],
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[] |
[] |
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DerChirurg.00710331.eng.abstr
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DerChirurg.00710331.eng.abstr
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"The treatment of choice in retroperitoneal liposarcoma is curative R0 resection . However , there are high rates of reoperation due to recurrence . Our present case report shows difficulties in detecting recurrence due to atypical configuration . Eventually a huge diverticulum of the duodenum combined with leiomyoma in its neck area was histopathologically identified as a recurrent liposarcoma ."
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[] |
[] |
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DerChirurg.00710334.eng.abstr
|
DerChirurg.00710334.eng.abstr
|
[
{
"id": "DerChirurg.00710334.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Abstract . Introduction : Primary liposarcoma of the stomach wall is rare . Only eight cases have been described so far . Material and method : Here we report the ninth case , occurring in a 74-year-old woman who presented with weight loss and a therapy-resistant ulcer of the stomach wall . Results : Pre- and perioperative findings suggested a benign lipoma of the stomach wall . The patient was treated with subtotal gastrectomy . On microscopic examination the tumor showed features of a benign lipoma but for a distinctive capillary net . Immunohistochemically the S-100 reaction was positive . Less than 1 % of Ki67-positive cells could be found , thus suggesting a highly differentiated primary liposarcoma of the stomach wall . Conclusion : In situations where the benign or malignant nature of a submucosal lesion cannot be diagnosed with certainty a mesenchymal tumor of the stomach wall has to be included in the differential diagnosis . Here the indication for complete surgical excision and histological workup has to be set widely ."
],
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DerChirurg.00710337.eng.abstr
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DerChirurg.00710337.eng.abstr
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"Abstract . Surgery of the great veins inevitably began with the surgical treatment of injuries , often involving the femoral vein . Because of the famous case presented by Roux in 1813 , the prevailing opinion until almost the end of the nineteenth century was that ligation of the vein made death inevitable , but that the only way to control severe hemorrhaging from a vein was to ligate the femoral artery . Zaufal's principle ( 1880 ) consisted in the ligation and resection of great veins of the body and limbs in order to prevent sepsis in suppurative processes . This surgical method was still being used in the first half of the twentieth century in patients with perforated appendicitis or puerperal fever . In the limb , the congestion induced in the vein had a positve effect on the healing process . The surgical treatment of leg and pelvic deep vein thrombosis was initially ( 1931 ) aimed at achieving decompression in compartment syndromas . The first thrombectomy was performed in 1937 , but several operations with a successful outcome were reported at the 61st annual meeting of the German Society of Surgery in the following year ."
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DerChirurg.00710355.eng.abstr
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DerChirurg.00710355.eng.abstr
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"Abstract . Abnormal surgical bleeding may be caused by congenital or acquired plasmatic and/or thrombocytic coagulation disorders . They may be known at the time of operation , or they may occur during the perioperative course for the first time . A detailed identification of haemostatic defects can be performed by a diagnostic spectrum of multiple tests . However , in clinical practice global screening tests are used first . In diagnostic routine three groups of patients have to be considered : ( 1 ) patients with no personal or family history of bleeding and no operative bleeding risk ; ( 2 ) patients with no history , but increased bleeding risk by the planned procedure ; ( 3 ) patients with a known haemorrhagic diathesis in their own history . In all difficult situations a specialist in haemostasiology should be consulted , because only rational diagnosis and therapeutic monitoring achieve an optimal and cost-effective operative result . The surgeon should always be aware that surgical bleeding from an operative cause must be considered in the differential diagnosis ."
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[] |
[] |
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DerChirurg.00710369.eng.abstr
|
DerChirurg.00710369.eng.abstr
|
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"Abstract . Across centers , transfusion can vary eightfold for the same mediastinal drainage after adult cardiac operations . Excessive blood drainage resulting in increased transfusions occurs in 29 % of patients . Various strategies have been proposed to decrease bleeding and allogenic transfusion requirements in the perioperative period of heart surgery . Blood conservation methods were reviewed critically . Avoidance of preoperative anemia , tolerance of low hemoglobin concentrations , the use of autologous blood , and adherence to a strict transfusion protocol will reduce the use of allogenic transfusions . Perioperatively , maintenance of normothermia contributes to improved hemostasis ."
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DerChirurg.00710374.eng.abstr
|
DerChirurg.00710374.eng.abstr
|
[
{
"id": "DerChirurg.00710374.eng.abstr-passage-0",
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"text": [
"Abstract . Viral hepatitis is one of the most important infectious diseases worldwide . It is frequent in tropical and subtropical areas , but also plays still a significant role in the industrialized countries of Northern and Western Europe and the USA . In Germany more than 100 000 people are infected by viral hepatitis each year . Whereas hepatitis A and E are transmitted fecal-orally , hepatitis B , C and D are transmitted by the parenteral route . Most hepatitis A infections seen in Germany are acquired abroad . Hepatitis B is still a nosocomial disease ; the majority of infections in Germany , however , seems to be transmitted sexually . For the serological diagnosis of viral hepatitis a battery of sensitive tests for specific antibodies and antigens is available ; usually testing of one serum sample allows an unambiguous diagnosis . Prophylaxis of hepatitis A and B is possible using safe and efficient vaccines ."
],
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0,
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[] |
[] |
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] |
DerChirurg.00710389.eng.abstr
|
DerChirurg.00710389.eng.abstr
|
[
{
"id": "DerChirurg.00710389.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Abstract . This report analyzes 46 cases of personnel-to-patient transmissions of hepatitis B ( HB ) , hepatitis C ( HC ) and HIV in health care settings . Similar circumstances were found for transmission of HB ( 40 cases , 404 infected patients ) , HC ( 4 cases , 224 infected patients ) and HIV ( 2 cases , 7 infected patients ) . Cases with the highest number of transmissions ( one anesthesiologist with 217 HC transmissions , and one EEG technologist with 75 HB transmissions ) were attributed to poor infection control practices . As long as infected health care workers ( HCW ) adhere to general infection control measures , a risk for transmission to patients exists only from infected surgeons who perform'xposure-prone invasive procedures ' . Whether changes in duties of infected HCW are necessary should be decided on an individual basis . Often , the infected personnel were assumed to have acquired the disease occupationally . Medical practices and devices bearing a risk of infection should constantly be reviewed with regard to risk for patients and personnel ."
],
"offsets": [
[
0,
1079
]
]
}
] |
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DerChirurg.00710396.eng.abstr
|
DerChirurg.00710396.eng.abstr
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"Abstract . In the United States of America ( 1991 ) , in Canada ( 1998 ) , in the UK ( 1993 , 1994 ) and in Germany ( 1999 ) recommendations have been published concerning performance of \" exposure-prone procedures \" ( EPP ) by persons infected with Hepatitis-B virus ( HBV ) , Hepatitis-C virus ( HCV ) or HIV . This review summarises the definition of EPP , methods to reduce the transmission of blood-borne pathogens , immunisation and screening policies , constitution of an advisory panel and the question of trace-back investigations described in these regulations ."
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] |
DerChirurg.00710404.eng.abstr
|
DerChirurg.00710404.eng.abstr
|
[
{
"id": "DerChirurg.00710404.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Chronic hepatic dysfunction and acute liver failure due to viral hepatitis represent the most frequent indications for liver transplantation . Liver grafting is the only available life-saving intervention for most of these patients . Reinfection of the graft is still a central problem . In hepatitis B , reinfection frequently leads to cirrhosis with subsequent dysfunction of the graft . Prophylaxis of HBV reinfection with polyclonal human antibodies against HBsAg alone or in combination with the nucleoside analogue lamivudine is effective but costly . Reinfection in hepatitis C is a regular event in all patients and has a far better prognosis than HBV reinfection of the graft . Effective prophylaxis of HCV reinfection has still not been established and requires further studies . After HCV reinfection the prognosis of allograft survival is negatively affected ; however , the 5-year survival rate in patients who have undergone liver transplantation for HCV-related liver disease is not lower than for other non-viral benign indications ."
],
"offsets": [
[
0,
1049
]
]
}
] |
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DerChirurg.00710410.eng.abstr
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DerChirurg.00710410.eng.abstr
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"Abstract . The 5-year survival of patients with colorectal cancer UICC stage I and II ranges from 70 % to 80 % . Therefore , at least 20 % to 30 % of these patients develop recurrent disease , caused by hematogenic or lymphogenic tumor cell dissemination . Using immunohistochemical or molecular biological methods , disseminated tumor cells can be detected in lymph nodes in a high proportion of patients in UICC stage I or II . The detection of disseminated tumor cells could help to identify a subgroup of patients at risk for disease relapse who could benefit from adjuvant therapy . Lymphogenic tumor cell dissemination seems to be a very common event in early colorectal cancer , preceding hematogenic tumor cell dissemination . Although these observations appear to confirm the therapeutic importance of meticulous lymph node dissection , their prognostic relevance has yet to be determined in prospective studies ."
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[] |
[] |
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DerChirurg.00710417.eng.abstr
|
DerChirurg.00710417.eng.abstr
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"Abstract . The health reform 2000 in Germany has little impact on the structural deficits of the German health service . The monopolies of hospitals for inpatient and of contract doctors for outpatient care are not changed . The budgeting of hospitals remains . In future there will be a catalog of operations that may only be carried out on an outpatient basis . The duty for quality assurance is specified and intensified . Implementation of innovative medical treatments in hospital will to be done only under strict control of a new countrywide committee . A new DRG-based price system for hospitals will be established ."
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}
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DerChirurg.00710424.eng.abstr
|
DerChirurg.00710424.eng.abstr
|
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"id": "DerChirurg.00710424.eng.abstr-passage-0",
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"text": [
"Abstract . Introduction : Serous cystadenomas of the pancreas are rare tumors and thought to be almost always benign . Methods : We report our experience in the diagnosis and surgical treatment of 12 patients with these tumors . Results : Between October 1993 and December 1998 , 41 patients with cystic tumors of the pancreas underwent surgical resection ; in 12 cases ( 11 women , 1 man ) a serous cystadenoma ( 10 micrcocystic , 2 oligomacrocystic ) was found . Only 6 ( 50 % ) patients had symptoms . The mean tumor size was 4.8 ( 2.7-10) cm . Ultrasound , CT and MRT usually could detect the mass , but differentiation with other cystic lesions was not reliable . All tumors were resected : 4 Whipple procedures , 7 distal pancreatectomies and 1 segmental resection were performed . No patient died after surgery and none had to be reoperated on . Conclusions : Because of the difficulty in reliably differentiating benign and malignant lesions of the pancreas , we believe that cystic tumors of the pancreas should be resected ."
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[] |
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DerChirurg.00710436.eng.abstr
|
DerChirurg.00710436.eng.abstr
|
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"id": "DerChirurg.00710436.eng.abstr-passage-0",
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"Abstract . Introduction : Endovascular therapy of aortic aneurysms is an attractive alternative to conventional aortic surgery . A number of patients , however , will fail endovascular therapy and require open surgical repair . Methods : We report our experience with conversion to open aortic repair . Of 306 patients given endovascular therapy for an infrarenal aortic aneurysm , 30 ( 9.8 % ) required conversion to conventional repair . Results : Thirteen patients ( 43.3 % ) suffered complications , 3 ( 10 % ) of which were fatal . Conversion to open aortic repair after endovascular therapy is technically more demanding than primary open repair , particularly because of clamp techniques and stent-extraction . Conclusions : Emergent conversion operations , especially when preceded by significant retroperitoneal bleeding from vascular tears due to endovascular manipulations are complicated by significant morbidity and mortality ."
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0,
940
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]
}
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] |
[] |
[] |
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DerChirurg.00710444.eng.abstr
|
DerChirurg.00710444.eng.abstr
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"Abstract . Epidemiologic data suggest that an underlying genetic disposition can be detected in up to 10 % of all colorectal cancer patients and autosomal dominantly inherited hereditary non-polyposis colorectal cancer ( HNPCC ) is the entity most frequently identified . It was described first by A. Warthin in 1895 in \" Family G \" and is characterized by a predisposition to an early onset of colorectal cancer and other intestinal or genitourinary tumors . We report the case of a 61-year-old woman with five different cancers . Although the strict Amsterdam Criteria were not fulfilled , molecular analysis revealed HNPCC ; further genetic testing in the family confirmed that the 36-year-old and so far healthy son had inherited the germline mutation of his affected mother . Genetic testing in clinically suspected HNPCC cases is recommended for patients with colorectal cancer meeting the Amsterdam Criteria . In patients meeting one of Bethesda Criteria 2-7 without meeting the Amsterdam Criteria , germline mutation analysis is recommended only in MSI-positive tumors ."
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[] |
[] |
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DerChirurg.00710448.eng.abstr
|
DerChirurg.00710448.eng.abstr
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"Abstract . Morbid obesity ( body mass index > 40 kg/m2) is a risk factor for cardiovascular , pulmonary , metabolic , neoplastic , and psychologic sequelae . In the present prospective clinical study 65 patients ( 11 men , 54 women ) underwent vertical banded gastroplasty ( Mason procedure ) from June 1994 to October 1997. The median age was 41 +/- 5.3 years ( range 18-69 ; n = 65 ) . Preoperative body weight was 135 +/- 23 kg ( 96-229 ; n = 65 ) , excess body weight in kg was 75 +/- 6.9 ( 44-155 ; n = 65 ) or in % 126 +/- 10 ( 78-223 ; n = 65 ) and BMI was 49 +/- 7.4 kg/m2 ( 39-69 ; n = 65 ) . Mean hospital stay was 9.7 +/- 2.4 days ( 6-18 ; n = 65 ) . Hospital mortality was 0 % ( 0/65 ) . Early complications were vomiting ( 30 % ) and problems in wound healing ( 15 % ; n = 65 ) . Late complications ( > 30 days ) were incisional hernias ( 13.8 % ) and staple-line disruptions ( 12.3 % ; n = 65 ) with a reoperation rate of 23 % ( 15/65 ) . Median follow-up was 15.0 +/- 5.2 months ( 2-42 ) with a follow up rate of 100 % . Mean weight loss after 12 months was 38.5 +/- 17 kg ( 30-98 ; n = 34 ) ( P 0.0001 ) and loss of excessive body weight 65 +/- 10 % ( 57-86 ; n = 34 ) , respectively ( P 0.0001 ) . Cardiovascular risk factors ( hypertension , diabetes , hyperlipidemia ) were significantly improved within 12 months ( n = 34 ) . Vertical banded gastroplasty ( Mason procedure ) - well established for 20 years - is a good , safe therapy for morbid obesity if strict indications for operation are observed and if there is multidisciplinary long-term follow-up . Co-morbid risk factors are considerably reduced and a long-term weight loss of more than 50 % can be achieved without the risk of pathological metabolic changes ."
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[] |
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DerChirurg.00710458.eng.abstr
|
DerChirurg.00710458.eng.abstr
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}
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[] |
[] |
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DerChirurg.00710462.eng.abstr
|
DerChirurg.00710462.eng.abstr
|
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{
"id": "DerChirurg.00710462.eng.abstr-passage-0",
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"text": [
"Abstract . Budd-Chiari syndrome is a rare manifestation of hereditary or acquired thrombophilia . We saw a case of Budd-Chiari syndrome in a 30-year-old woman leading to initial diagnostic difficulties . She underwent surgical side-to-side shunt and 9 weeks later an almost normal liver could be demonstrated on computerized tomography . Budd-Chiari syndrome should be considered if the Chiari triad with abdominal pain , hepatomegaly and ascites occurs in a patient . If necessary , invasive diagnostic procedures ( e.g. angiography ) must be performed . Therapeutic options are anticoagulative therapy and porto-systemic shunt , either as a TIPS or a surgical shunt . If severe liver failure occurs or liver cirrhosis is present , orthotopic liver transplantation is an additional option which also cures hereditary thrombophilia ."
],
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}
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] |
[] |
[] |
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DerChirurg.00710466.eng.abstr
|
DerChirurg.00710466.eng.abstr
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[] |
[] |
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{
"id": "DerChirurg.00710466.eng.abstr-s4-r2-t1.1-t3.1",
"type": "precedes",
"arg1_id": "DerChirurg.00710466.eng.abstr-s4-t1",
"arg2_id": "DerChirurg.00710466.eng.abstr-s4-t3",
"normalized": []
}
] |
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