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Gefaesschirurgie.90040020.eng.abstr
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Gefaesschirurgie.90040020.eng.abstr
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"Technological advances in spiral CT scanners and their workstations have changed the common perception of computed tomography in vessel imaging . The less invasive character of CTA examination compared to intraarterial DSA can transform this method into the which is viable clinically to increase diagnostic utility . However , the 2D axial images do not optimally communicate the 3D nature of the anatomy and pathology involved . The option to render 3D angiogram-like images can be combined with the diagnostic exploitation of the volume data information . The choice of the rendering technique to create 3D images from the data set greatly affects the quality and efficacy of CTA data . The commonly used rendering techniques are surface shaded display ( SSD ) and maximum intensity projection ( MIP ) . Volume rendering ( VR ) as a relatively new modality may have the potential to replace the other rendering techniques . For critical image evaluation it is important to know the basic principles , advantages , disadvantages and limitations of these algorithms ."
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[] |
[] |
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Gefaesschirurgie.90040028.eng.abstr
|
Gefaesschirurgie.90040028.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040028.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A total of 61 patients suffering from weight loss and epigastric pain were screened by color flow Duplex imaging ( CFDJ ) of the abdominal vessels . Criteria for diagnosis were ( 1 ) peak flow in the celiac axis ( CA ) of more than 200 cm/s ; ( 2 ) fixing of the CA stenosis during expiration and inspiration , and ( 3 ) steal phenomenon and reversal of flow in the superior mesenteric artery ( SMA ) . Results : Of 61 patients 21 ( 34.4% ) fulfilled the criteria ; 38 ( 62.3% ) were excluded , and 2 patients could not be evaluated . Of 21 patients 10 were operated on after confirming diagnosis by angiography of CA and SMA . All patients survived . After a follow-up of 28 months 80% of the operated patients were free of symptoms , 10% improved , and 10% showed no change . Conclusion : Successful operative treatment of CA compression includes ( 1 ) CFDJ of CA and SMA proving stenosis persisting in inspirational position of the diaphragm ; ( 2 ) angiography of CA and SMA showing a steal phenomenon including blood flow reversal in SMA ; ( 3 ) triad of symptoms : epigastric pain , postprandial pain and weight loss ; and ( 4 ) exclusion of other causes , i.e. pancreatic cancer , pancreatitis etc."
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] |
Gefaesschirurgie.90040034.eng.abstr
|
Gefaesschirurgie.90040034.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040034.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Purpose : The aim of the study was to apply laparoscopic techniques in reconstructive procedures for aortoiliac occlusive disease . Methods : From February 1996 to February 1998 , 16 patients underwent a laparoscopic aortobifemoral bypass procedure ( ABF ) using the transperitoneal approach . Six , 5 to 12 mm ports were needed to dissect , cross-clamp and divide the infrarenal aorta using specific laparoscopic devices . The aortic anastomosis was made end-to-side . A long curved clamp was then passed from each groin to draw the limbs of the graft into the femoral incision . The distal anastomosis was then performed conventionally . Results : The laparoscopic ABF was performed successfully in 13 of 16 cases . Three times a conversion to open surgery was requested . One patient developed respiratory insufficiency requiring prolonged treatment on the ICU . Mean operative time was 292 +/- 60 min ; the aorta was crossclamped for 74 +/- 18 min . Two patients needed transfusions of red blood cells . In the study group , blood loss averaged 566 +/- 434 ml . The bypass patency and the correct positioning of the graft were assessed by angiography . The patients were discharged 9 +/- 5.8 days after surgery . At follow-up after 4.5 +/- 4 months , 15 patients were examined noninvasively in the vascular laboratory . All grafts were patent , and the ischemic symptoms had resolved in 14 patients . One patient with recurrent claudication had severe stenosis of the left distal anastomosis . Conclusions : The laparoscopic aortobifemoral bypass is a feasible , safe and effective procedure . Specific laparoscopic instruments are required for the challenging procedure . The development of vascular staplers and retraction devices will probably reduce the operative time and the technical challenge . In the future this operative technique may gain relevance as a minimally invasive procedure for severe aortoiliac occlusive disease ."
],
"offsets": [
[
0,
1940
]
]
}
] |
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}
] |
Gefaesschirurgie.90040040.eng.abstr
|
Gefaesschirurgie.90040040.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040040.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In the last 7 years we have performed 220 infrainguinal vein bypasses associated with critical limb ischemia . All patients were prospectively controlled in a follow-up program 3 - 72 months postoperatively . The patients were divided into two groups : patients with diabetes mellitus ( 35% , group 1 ) and patients without diabetes mellitus ( 65% , group 2 ) . There was no difference in sex , age or localization of distal anastomosis ( supra- or infragenicular ) between the two groups . The primary and the primary-assisted patency rates were not statistically different after 60 months . There was a significant difference in limb salvage . The limb salvage of group 1 was 75% after 60 months , while the limb salvage of group 2 was 95% ( P = 0.0045 ) . The rate of major amputations was significantly higher in group 1 ( 15.6% ) than in group 2 ( 4.9% , P = 0.007 ) . The indication for amputation was persistent foot infection ."
],
"offsets": [
[
0,
935
]
]
}
] |
[
{
"id": "Gefaesschirurgie.90040040.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"vein"
],
"offsets": [
[
56,
60
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0042449"
}
]
},
{
"id": "Gefaesschirurgie.90040040.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"limb"
],
"offsets": [
[
95,
99
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0015385"
}
]
},
{
"id": "Gefaesschirurgie.90040040.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"ischemia"
],
"offsets": [
[
100,
108
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0022116"
}
]
},
{
"id": "Gefaesschirurgie.90040040.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"All"
],
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[
111,
114
]
],
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{
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}
]
},
{
"id": "Gefaesschirurgie.90040040.eng.abstr-s2-t2",
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"text": [
"patients"
],
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]
],
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]
},
{
"id": "Gefaesschirurgie.90040040.eng.abstr-s2-t3",
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"text": [
"program"
],
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[
169,
176
]
],
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"db_name": "UMLS",
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{
"id": "Gefaesschirurgie.90040040.eng.abstr-s3-t1",
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"patients"
],
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]
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},
{
"id": "Gefaesschirurgie.90040040.eng.abstr-s3-t2",
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"text": [
"patients"
],
"offsets": [
[
253,
261
]
],
"normalized": [
{
"db_name": "UMLS",
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}
]
},
{
"id": "Gefaesschirurgie.90040040.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"diabetes"
],
"offsets": [
[
267,
275
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0011847"
},
{
"db_name": "UMLS",
"db_id": "C0011849"
}
]
},
{
"id": "Gefaesschirurgie.90040040.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"patients"
],
"offsets": [
[
307,
315
]
],
"normalized": [
{
"db_name": "UMLS",
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}
]
},
{
"id": "Gefaesschirurgie.90040040.eng.abstr-s3-t5",
"type": "umlsterm",
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] |
[] |
[] |
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] |
Gefaesschirurgie.90040050.eng.abstr
|
Gefaesschirurgie.90040050.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040050.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Armand Trousseau ( 1801-1867 ) was the first to recognize that phlegmasia alba is frequently associated with tumour disease . His main work , Clinique médicale de la Hôtel-Dieu de Paris , contains impressive case histories . On the basis of a phlebitis that occurred in his own left arm he diagnosed himself with gastric cancer , and this was in fact the cause of his death . Trousseau is one of the most famous doctors of all time . Numerous discoveries in the area of internal medicine go back to him . Following his tutor , Bretonneau , he introduced the performance of tracheotomy as a routine operation for diphtheritic croup ; he also devised the technique of thoracocentesis . He concerned himself particularly with the infectious diseases of the time and with neurology ."
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] |
[] |
[] |
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Gefaesschirurgie.90040081.eng.abstr
|
Gefaesschirurgie.90040081.eng.abstr
|
[
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"Peripheral vascular disease is an important cause of morbidity and mortality , and over 3000 trials relating to its management have been published . Systematic reviews of this evidence are urgently required , as it is impossible for the individual clinician to sift through and evaluate all this information . The Cochrane Collaboration was established in 1992 to produce systematic reviews of all aspects of health care , and includes a Review Group specifically addressing issues relating to peripheral vascular disease . This is an international group examining all aspects of peripheral vascular disease , including abdominal aortic aneurysm , atherosclerotic disease of the lower limb , varicose veins , thromboembolism , and vasospastic disorders . Several reviews in key areas have been published , including the evidence for angioplasty , lipid-lowering therapy and exercise in intermittent claudication . More reviews are urgently required , and anyone with interest and enthusiasm is invited to contribute ."
],
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0,
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]
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Gefaesschirurgie.90040085.eng.abstr
|
Gefaesschirurgie.90040085.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040085.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Introduction : The efficacy of vascular surgery in the treatment of popliteal arterial aneurysms ( PAA ) and the justification of conservative therapy was investigated in the present study . Materials and methods : From January 1985 to December 1996 , 87 patients were operated on for PAA . The clinical records were reviewed retrospectively and patients were categorized concerning PAA-related symptoms , vascular run-off , and material used for vascular reconstruction . Patients were examined , and the patency of the vascular reconstruction was checked by palpation and Doppler sonography . Results : The cumulative survival calculated using the Kaplan-Meier curve was 70% after 10 years . Asymptomatic patients had the best results and patients with acute ischemia , the worst . The outcome concerning patent vs. occluded run-off and autologous vs. heterologous bypass material was similar . Conclusion : Asymptomatic and uncomplicated PAA should be treated surgically . Only PAA with a diameter less than 2 cm , and without thrombus on the vessel walls can be treated conservatively ."
],
"offsets": [
[
0,
1090
]
]
}
] |
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}
] |
[] |
[] |
[
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"type": "associated_with",
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}
] |
Gefaesschirurgie.90040091.eng.abstr
|
Gefaesschirurgie.90040091.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040091.eng.abstr-passage-0",
"type": "abstract",
"text": [
"At present there is neither an completely inert biomaterial available , nor does a universal test exist which objectively evaluates biocompatibility . One reason is the individuality of the host , especially with regard to the inflammatory response . Inflammation was found to induce biodegradation by hydrolysis or auto-oxidation of vascular prosthetic matrix after implantation . The present study was performed to investigate the specific humoral immune response after implantation of segments of a collagen-impregnated polyester prosthesis ( Dacron ) in Balb/c mice on experimental days 1 , 18 , 38 , and 322. Serum antibody detection was performed by modified enzyme immunoassay using the prosthesis as a target . Specific polymer antibodies , enhanced by repeated implantations , could be detected in all mice which received grafts up to experimental day 322. These antibodies were not directed against the collagen coating . The antibody formation could be further enhanced by a combined administration of complete Freund's adjuvant together with the first implantation at experimental day 1. Results suggest that specific polymer antibodies , reflecting an inflammatory response , might be an additional parameter for biocompatibility testing of vascular prostheses ."
],
"offsets": [
[
0,
1275
]
]
}
] |
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{
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{
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{
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{
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{
"id": "Gefaesschirurgie.90040091.eng.abstr-s5-t5",
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{
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{
"id": "Gefaesschirurgie.90040091.eng.abstr-s6-t8",
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{
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}
] |
[] |
[] |
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"arg1_id": "Gefaesschirurgie.90040091.eng.abstr-s6-t5",
"arg2_id": "Gefaesschirurgie.90040091.eng.abstr-s6-t1",
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},
{
"id": "Gefaesschirurgie.90040091.eng.abstr-s6-r38-t8.2-t6.1",
"type": "produces",
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"arg2_id": "Gefaesschirurgie.90040091.eng.abstr-s6-t6",
"normalized": []
}
] |
Gefaesschirurgie.90040096.eng.abstr
|
Gefaesschirurgie.90040096.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040096.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Four years after extensive pneumonectomy on the left side with resection of the aortic wall and patch reconstruction for a T4 carcinoma , 2 years after adjuvant radiation and 10 months after drainage therapy of late intrathoracic empyema , destruction of the infected Dacron patch led to rupture of the aorta descendens . Successful primary emergency reconstruction of the aorta descendens was followed by venetian blind plasty ( Heller ) and transposition of the omentum majus for omentoplasty of the aortal wall and reduction of the pneumonectomy cavity . The rate of prosthetic infections is between 0.3 and 2.5% and must be taken into consideration even in cases of intrathoracic vascular reconstruction with alloplastic prostheses . After lung resection it is necessary to cover up the prosthetic graft by using autogenous material to obtain prosthetic incorporation into the protective tissue . In intrathoracic infectious complications , extra-anatomic bypass grafting or autogenous vascular graft implantation should be considered . If there is no possibility of carrying out these procedures , first aggressive local debridement of the infected vascular wall and afterwards coverage with alloplastic prosthetics with omentum transposition and thoracoplasty are essential to minimize postoperative infection and obtain solid anchorage in the surrounding tissue ."
],
"offsets": [
[
0,
1370
]
]
}
] |
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"pneumonectomy"
],
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[
27,
40
]
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{
"db_name": "UMLS",
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}
]
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"carcinoma"
],
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126,
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{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"adjuvant"
],
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152,
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{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"radiation"
],
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},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"drainage"
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191,
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{
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"therapy"
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]
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-t7",
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"empyema"
],
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}
]
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-t8",
"type": "umlsterm",
"text": [
"Dacron"
],
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268,
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]
],
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}
]
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-t9",
"type": "umlsterm",
"text": [
"rupture"
],
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}
]
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-t10",
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"text": [
"aorta"
],
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{
"id": "Gefaesschirurgie.90040096.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"emergency"
],
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]
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"aorta"
],
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]
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s2-t3",
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"blind"
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}
]
},
{
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"type": "umlsterm",
"text": [
"omentum"
],
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}
]
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"pneumonectomy"
],
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],
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}
]
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"infections"
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]
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"prostheses"
],
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},
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]
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"lung"
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{
"id": "Gefaesschirurgie.90040096.eng.abstr-s4-t2",
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"graft"
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},
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}
]
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s4-t3",
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"incorporation"
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{
"id": "Gefaesschirurgie.90040096.eng.abstr-s4-t4",
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"complications"
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]
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]
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{
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"procedures"
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}
]
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"id": "Gefaesschirurgie.90040096.eng.abstr-s6-t4",
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"postoperative"
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{
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"infection"
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]
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s6-t7",
"type": "umlsterm",
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"tissue"
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]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0040300"
}
]
}
] |
[] |
[] |
[
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r1-t2.1-t3.1",
"type": "produces",
"arg1_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t2",
"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t3",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r2-t10.1-t6.1",
"type": "location_of",
"arg1_id": "Gefaesschirurgie.90040096.eng.abstr-s1-t10",
"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t6",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r3-t2.1-t4.1",
"type": "result_of",
"arg1_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t2",
"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t4",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r4-t2.1-t6.1",
"type": "associated_with",
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"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t6",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r5-t3.1-t4.1",
"type": "affects",
"arg1_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t3",
"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t4",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r6-t3.1-t10.1",
"type": "disrupts",
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"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s1-t10",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r7-t2.1-t5.1",
"type": "associated_with",
"arg1_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t2",
"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t5",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r8-t4.1-t9.1",
"type": "result_of",
"arg1_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t4",
"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s1-t9",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r9-t9.1-t4.1",
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},
{
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},
{
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"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r12-t6.1-t9.1",
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"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r13-t9.1-t6.1",
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"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t6",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r14-t6.1-t3.1",
"type": "produces",
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"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t3",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r15-t9.1-t5.1",
"type": "associated_with",
"arg1_id": "Gefaesschirurgie.90040096.eng.abstr-s1-t9",
"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t5",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r16-t8.1-t4.1",
"type": "affects",
"arg1_id": "Gefaesschirurgie.90040096.eng.abstr-s1-t8",
"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t4",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r17-t9.1-t2.1",
"type": "result_of",
"arg1_id": "Gefaesschirurgie.90040096.eng.abstr-s1-t9",
"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t2",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r18-t6.1-t4.1",
"type": "result_of",
"arg1_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t6",
"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t4",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r19-t8.1-t3.1",
"type": "interacts_with",
"arg1_id": "Gefaesschirurgie.90040096.eng.abstr-s1-t8",
"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t3",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r20-t10.1-t2.1",
"type": "location_of",
"arg1_id": "Gefaesschirurgie.90040096.eng.abstr-s1-t10",
"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t2",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r21-t9.1-t1.1",
"type": "associated_with",
"arg1_id": "Gefaesschirurgie.90040096.eng.abstr-s1-t9",
"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t1",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r22-t4.1-t2.1",
"type": "result_of",
"arg1_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t4",
"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t2",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r23-t3.1-t6.1",
"type": "diagnoses",
"arg1_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t3",
"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t6",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r24-t3.1-t6.1",
"type": "indicates",
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"arg2_id": "Gefaesschirurgie.90040096.eng.abstr-s6-t6",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040096.eng.abstr-s1-r25-t10.1-t1.1",
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] |
Gefaesschirurgie.90040101.eng.abstr
|
Gefaesschirurgie.90040101.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040101.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Secondary aortoenteric fistulas are a well-known complication after open repair of an abdominal aortic aneurysm . This is the first case description of an aortoenteric fistula after endoluminal treatment of an abdominal aortic aneurysm . Preoperative diagnosis by antigranulocyte immunscintigraphy established infection of the protheses . The problem was solved by closing the defect of duodenum , removing the endoprotheses and in situ reconstruction with omentumplasty . The reasons and consequences are discussed ."
],
"offsets": [
[
0,
517
]
]
}
] |
[
{
"id": "Gefaesschirurgie.90040101.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"Secondary"
],
"offsets": [
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] |
Gefaesschirurgie.90040105.eng.abstr
|
Gefaesschirurgie.90040105.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040105.eng.abstr-passage-0",
"type": "abstract",
"text": [
"For several years now , external comparative quality assurance for surgical tracer diagnosis has proven helpful and produced important evidence . Venous insufficiency is a considerable medico-economic issue . Even so , there is to date no defined consensus on pre- and postoperative diagnostic methods , operative procedures , and after treatment in varicose vein surgery . Nationwide data on the methods used , patient satisfaction , and the quality of patient care are lacking . This is why external quality assurance is required in surgery of varicose veins and also required by German federal law ( SGB V ) ."
],
"offsets": [
[
0,
612
]
]
}
] |
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{
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{
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{
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{
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{
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{
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] |
[] |
[] |
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Gefaesschirurgie.90040130.eng.abstr
|
Gefaesschirurgie.90040130.eng.abstr
|
[
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"The question of how to optimal employ postoperative pharmacotherapy following peripheral artery interventions remains controversial , although peripheral bypass operations provide an excellent model for various antithrombotic regimens . The aim of this overview is to evaluate current attitudes and discuss future aspects of adjunctive treatment . Based upon different review articles and a literature search employing the Random Controlled Trials Registry of the Cochrane Library Data Base , we used the recommendations of the Ad Hoc Committee on \" Clinical Research and Vascular Surgery \" of the Vascular Surgery Society ( SVS ) to evaluate the various levels of available evidence on how best to employ antithrombotic therapy . The grade A recommendation is the most scientifically sound , usually definitive , advice based upon large numbers of patients ; the trial was prospectively randomized , placebo-controlled , and double-blind ( ? ) ; it is therefore of multicentric design . The grade-C recommendation is derived from non-randomized comparative studies using either contemporaneous or historical controls , or case histories . Heparin is widely used among vascular surgeons , although the methods of application vary ; therefore only a grade C recommendation is appropriate . Platelet active agents , acetyl salicylic acid in particular , in medium doses , are the most intensely tested substances , so the advice for long-term ( lifelong ? ) use regarding patency and survival is based on the highest level of evidence from many large trials and meta-analyses ; thus , a grade A recommendation is justified . Ticlopidine shows promise , but further confirmative evidence is needed . The combination of antiplatelet drugs and anticoagulants might be a worthwhile option , although the risk of complications is substantial . A combination of the two , but in reduced dosages , might turn out to be attractive . Low-molecular-weight dextran has been shown in a multicentre trial to be effective in short-term use , so a grade A recommendation seems justified ."
],
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] |
Gefaesschirurgie.90040138.eng.abstr
|
Gefaesschirurgie.90040138.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040138.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Heparin-induced or -associated thrombocytopenia type II ( HIT II ) is the most important clinical side effect of heparin therapy . At the University Hospital of Jena the detection of HIT II antibodies has been done using the heparin-induced platelet activation assay ( HIPA ) since 1995. During this period , 89 patients of the surgical clinic were examined under a clinical suspicion of HIT II syndrome . Indication for the HIPA was thrombocytopenia or any thrombembolic complication during therapy with heparin . In 21 patients the results were positive . In 15 cases , prior to the diagnosis of HIT II , complications known as white clot syndrome occurred [ pulmonary embolism ( n = 1 ) , shunt reocclusion ( n = 3 ) , arterial thrombosis , embolism or reocclusion of bypass ( n = 8 ) , deep vein thrombosis ( n = 4 ) ] . 8 patients had a history of similar events during earlier phases of therapy with heparin . Three of the patients died . Therapy with heparin implies frequent control of thrombocyte count . In any case of thrombocytopenia and/or thrombembolic complications testing for HIT II antibodies is necessary . If it is positive and vascular reconstruction is indicated , we recommend hirudin for anticoagulation ."
],
"offsets": [
[
0,
1229
]
]
}
] |
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[] |
[] |
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}
] |
Gefaesschirurgie.90040158.eng.abstr
|
Gefaesschirurgie.90040158.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040158.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The surgical correction of a tandem stenosis of the carotid artery is sometimes difficult , especially if the second stenosis is near or above the skull base . Angioplasty and Stent implantation may offer an alternative to standard surgical procedures in the treatment of carotid stenoses in the future . However , the potential advantages of these endovascular techniques warrant continued evaluation . The application of these techniques in carotid artery tandem stenoses presents specific problems and dangers . We discuss the case of a 78-year-old man with severe carotid stenoses on both sides and an additional symptomatic tandem stenosis above the skull base on the right side . After the surgical correction of the left carotid artery using standard endarterectomy , we performed endarterectomy on the right side in combination with an open Stent implantation ."
],
"offsets": [
[
0,
869
]
]
}
] |
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{
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"stenosis"
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"artery"
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"stenosis"
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"type": "umlsterm",
"text": [
"skull"
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{
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{
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"text": [
"Angioplasty"
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160,
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{
"id": "Gefaesschirurgie.90040158.eng.abstr-s2-t2",
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"text": [
"Stent"
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176,
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]
}
] |
[] |
[] |
[
{
"id": "Gefaesschirurgie.90040158.eng.abstr-s1-r1-t8.1-t7.2",
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Gefaesschirurgie.90040162.eng.abstr
|
Gefaesschirurgie.90040162.eng.abstr
|
[
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"id": "Gefaesschirurgie.90040162.eng.abstr-passage-0",
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"text": [
"A phlebological report requires that an exact diagnostic investigation of the peripheral vein system be carried out to assess both function and morphology . The most important , reproducible findings can be obtained using dynamic phlebodynamometry and ascending pressure phlebography , as a second expert can directly reconstruct the process by which assessments have been made . Additional quantification information can be obtained by measuring reflux using colour- coded duplex sonography . A thrombophilic condition should always be investigated in terms of haemotasis . In patients with severe post-thrombotic disease , a chronic compartment syndrome of the posterior spaces should be reckoned with , and in such patients magnetic resonance imaging , computed tomography and , if possible , dynamic compartment manometry are additional suitable methods of examination . There is currently no generally valid schematization of the post-thrombotic syndrome on which to base an expert opinion . When evaluating patients , we largely follow our own new classification , which distinguishes four stages based on clinical tissue sclerosis ."
],
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]
}
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[] |
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Gefaesschirurgie.90040185.eng.abstr
|
Gefaesschirurgie.90040185.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040185.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Recent investigations have controversially but convincingly interpreted the pathogenesis of atherosclerosis ( arteriosclerosis ) . Atherosclerosis can apparently be the result of ultrachronic , persistent infection by Chlamydia pneumoniae and not the result of heterogenous risk factors . The main arguments for chlamydial genesis are : Correlation of coronary heart disease and other atherosclerotic diseases and antibodies against Chlamydia pneumoniae . ( 2 ) Chlamydia pneumoniae could be detected with different techniques ( PCR , ICC , immunhistology , electromicroscopy , culture ) in a high percentage of atheromas from different sites . ( 3 ) According to three successful international studies with macrolides in coronary heart disease . ( 4 ) Target cells of atherosclerosis ( endothelia , macrophages , muscle cells ) can be infected by Chlamydia pneumoniae in vitro . ( 5 ) Provocation of arteriitis in animal experiments . ( 6 ) The reduction of incidence of atherosclerotic diseases since the 1960s , probably due to advances in antibiotic treatment . ( 7 ) Elevated levels of acute-phase proteins and other inflammatory signs ( CRP , WBC count , fibrinogin ) briefly before cardiac infarction occurs . There are good arguments for intervention studies in coronary heart disease and other manifestations of atherosclerosis . The relevant antibiotics are available for chlamydial infections and are inexpensive and safe . Meticulous protocols and long-term monitoring of patients should be developed ."
],
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}
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] |
Gefaesschirurgie.90040194.eng.abstr
|
Gefaesschirurgie.90040194.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040194.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Background : The implantation of a femoro-popliteal bypass graft represents the gold standard in the management of arteriosclerotic occlusive disease in the femoro-popliteal region . Application of interventional techniques has permitted the development of a novel , endovascular implantable bypass system . The device is placed within the lumen of the superficial femoral artery . The present study investigated the technical properties of the new system in cadavers , with subsequent evaluation of its application in humans . Methods : The endopass consists of a thin-wall polycarbourethane tube with a total length of 53 cm . The distal end is connected with a self-expanding stent prothesis 4 cm in length . Endovascular implantation is performed through a groin incision . Following antegrade ringstripper-TEA , the endopass is introduced into the femoral artery after placement of a guide wire . The proximal anastomosis is performed surgically . Results : The technical requirements and feasibility of the system were tested on 12 cadaver extremities . Implantation of the device proved technically successful in seven of eight extremities with significant occlusion of the superficial femoral artery . The most important problems included the complete ringstripper-TEA , the placement of the guide wire following the TEA , and the expansion of the endopass . Following approval by the ethics commission , the endopass was implanted in five patients between June 1997 and March 1998. In three patients , the endopass remained patent and has functioned well . One patient with poor vascular outflow suffered an early noncorrectable occlusion , while in the remaining case , perforation secondary to the ringstripper procedure forced us to abandon the attempt . Conclusion : Experience from the cadaver study and initial human applications confirm the feasibility of this method . Further development and methodological improvement , however , are necessary requiring additional , larger studies on patients ."
],
"offsets": [
[
0,
2014
]
]
}
] |
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}
] |
[] |
[] |
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] |
Gefaesschirurgie.90040203.eng.abstr
|
Gefaesschirurgie.90040203.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040203.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The outcome in 163 patients treated for an abdominal aortic aneurysm in the department for vascular and thoracic surgery since its institution 5 years ago is investigated . Some 142 patients underwent operative aneurysm repair ; 21 ( 13% ) were excluded from operation . In 108 ( 66% ) an elective procedure was performed , an emergency operation for rupture 34 times ( 21% ) . In 16% of cases one or both renal arteries or the inferior mesenteric or the internal iliac artery were reimplanted . For further analysis the patients were split in three groups : elective group 1 , symptomatic group 2 , ruptured group 3. Significant differences were found in the aneurysmal diameter , distribution of gender ( 128 M , 14 F ) , renal artery involvement , or concomitant peripheral arteriosclerosis as well as for the risk factors tobacco smoking , hyperlipidemia , renal insufficiency , and the presence of multiple risk factors . Group 1 had a significantly higher preoperative hospital stay than group 2 ; whereas the intensive care stay was significantly longer in group 3 than in the other two groups . Sixty-four percent of patients had no , 11% had more than one complication . Mortality was 0 in groups 1 and 2 , but 35.3% in group 3. The most frequent complication in groups 1 and 2 was pneumonia ( 13.9% ) followed by cardiac complications ( 4.6% ) , and renal insufficiency ( 3.7% ) . In group 3 respiratory insufficiency demonstrated the highest incidence ( 23.5% ) , followed by renal insufficiency ( 21% ) and pneumonia ( 17.6% ) . No patient of the nonoperated group suffered an aneurysm rupture ; aneurysm diameters , except one , did not increase during the follow-up period . Of the 130 operated and discharged patients 31 died ; in no case was death related to the operative procedure . No important complications were observed during the follow-up of 37.2 +/- 17.9 months . Furthermore , the results are compared with those of the literature . Based on their observations the authors conclude that this retrospective quality check was rather awkward and involved giving partly incomplete data for lack of a prospective evaluation . Nevertheless , the results compared well with those in the literature and were satisfactory ."
],
"offsets": [
[
0,
2240
]
]
}
] |
[
{
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"patients"
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27
]
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{
"id": "Gefaesschirurgie.90040203.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"aneurysm"
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60,
68
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{
"id": "Gefaesschirurgie.90040203.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"aortic aneurysm"
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53,
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"db_id": "C0003486"
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[] |
[] |
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"arg2_id": "Gefaesschirurgie.90040203.eng.abstr-s14-t3",
"normalized": []
},
{
"id": "Gefaesschirurgie.90040203.eng.abstr-s14-r1-t1.1-t2.1",
"type": "measures",
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"arg2_id": "Gefaesschirurgie.90040203.eng.abstr-s14-t2",
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},
{
"id": "Gefaesschirurgie.90040203.eng.abstr-s14-r2-t3.1-t2.1",
"type": "measures",
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"arg2_id": "Gefaesschirurgie.90040203.eng.abstr-s14-t2",
"normalized": []
}
] |
Gefaesschirurgie.90040213.eng.abstr
|
Gefaesschirurgie.90040213.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040213.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Purpose : The experience with the endoluminal treatment of abdominal , infrarenal aortic aneurysms with two different stent devices is reported . Material and methods : Some 33 males and one female , between 52 and 81 years of age were treated for infrarenal aortic aneurysm . A Vanguard stent was used in 23 patients ( 19 bifurcated , four tube ) and a Talent stent in 11 ( seven bifurcated , four tube ) . The two different stent designs were selected depending on the diameter of the aneurysmal neck and the iliac arteries . All procedures were performed under general anaesthesia in the angiographic suite . Results : The primary technical success rate was 85.3% ; the secondary success rate was 91.1% . Primary and secondary clinical success were 61.7 and 79.4% respectively . During a follow-up of 22 months , we saw seven late complications , which required an open operation three times . Conclusion : With both stent systems , the same results as with open repair could not be reached . At present , the pros and cons for both systems seem to be balanced . Both are to be improved ."
],
"offsets": [
[
0,
1091
]
]
}
] |
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"treatment"
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{
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}
]
},
{
"id": "Gefaesschirurgie.90040213.eng.abstr-s1-t2",
"type": "umlsterm",
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"aneurysms"
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{
"id": "Gefaesschirurgie.90040213.eng.abstr-s1-t3",
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"stent"
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118,
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{
"id": "Gefaesschirurgie.90040213.eng.abstr-s1-t4",
"type": "umlsterm",
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"devices"
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]
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{
"id": "Gefaesschirurgie.90040213.eng.abstr-s1-t5",
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"aortic aneurysms"
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"males"
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}
]
},
{
"id": "Gefaesschirurgie.90040213.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"female"
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191,
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}
]
},
{
"id": "Gefaesschirurgie.90040213.eng.abstr-s2-t4",
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"age"
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]
},
{
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{
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{
"id": "Gefaesschirurgie.90040213.eng.abstr-s3-t1",
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"stent"
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{
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"type": "umlsterm",
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"patients"
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{
"id": "Gefaesschirurgie.90040213.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"Talent"
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{
"id": "Gefaesschirurgie.90040213.eng.abstr-s3-t4",
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{
"id": "Gefaesschirurgie.90040213.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"neck"
],
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{
"id": "Gefaesschirurgie.90040213.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"arteries"
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{
"id": "Gefaesschirurgie.90040213.eng.abstr-s4-t4",
"type": "umlsterm",
"text": [
"iliac arteries"
],
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"db_id": "C0020887"
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{
"id": "Gefaesschirurgie.90040213.eng.abstr-s5-t2",
"type": "umlsterm",
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]
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{
"id": "Gefaesschirurgie.90040213.eng.abstr-s5-t3",
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{
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{
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"type": "umlsterm",
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{
"id": "Gefaesschirurgie.90040213.eng.abstr-s9-t3",
"type": "umlsterm",
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"db_id": "C0043240"
}
]
}
] |
[] |
[] |
[
{
"id": "Gefaesschirurgie.90040213.eng.abstr-s1-r1-t3.1-t4.1",
"type": "isa",
"arg1_id": "Gefaesschirurgie.90040213.eng.abstr-s9-t3",
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},
{
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"type": "uses",
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},
{
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{
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{
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{
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{
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{
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},
{
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},
{
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{
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{
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{
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{
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},
{
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},
{
"id": "Gefaesschirurgie.90040213.eng.abstr-s2-r13-t5.1-t1.1",
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{
"id": "Gefaesschirurgie.90040213.eng.abstr-s2-r14-t6.1-t5.1",
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},
{
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},
{
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Gefaesschirurgie.90040220.eng.abstr
|
Gefaesschirurgie.90040220.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040220.eng.abstr-passage-0",
"type": "abstract",
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"Objective : In a substantial number of diabetic patients , isolated tibioperoneal arterial occlusions are found to be the underlying cause for severe ischaemic foot lesions . To avoid limb loss under these conditions , short vein grafts have been being used to bypass the occluded crural arteries since the early 1980s . This presentation describes our nearly 12-year experience with this strategy . Patients and methods : Between 1 May 1986 and 31 December 1997 , in 109 patients , 115 bypass grafts from the BK-popliteal artery or the proximal anterior tibial artery to malleolar vessels were performed in the presence of extended infrapopliteal arterial occlusions and critical foot ischaemia ( rest pain 3 , tissue loss 112 ) . The mean age in this group was 70.1 years . Autologous vein was used in all cases ( GSV rev . 79 , GSV nonrev . 17 , GSV in situ 15 , LSV rev . 2 , cephalic vein 2 ) . Results : Using life-table analysis , primary and secondary patency rates for these bypasses with distal graft origination were 89% and 97% at 30 days , 76% and 83% at 1 year , and 60% and 62% at 6 years , respectively . The corresponding limb salvage rates amounted to 94% , 79% , and 70% . Conclusion : Our results suggest that short vein grafts represent an effective strategy for limb salvage in diabetic patients with infrapopliteal artery occlusions and critical foot ischaemia ."
],
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] |
Gefaesschirurgie.90040229.eng.abstr
|
Gefaesschirurgie.90040229.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040229.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A 15-year-old youngster was hit in the abdomen by a 22 caliber rifle bullet . After a short , symptom-free interval , he collapsed and was transported rapidly to the nearest medical center . He showed severe shock and anemia . An explorative laparotomy was performed immediately and an extended retroperitoneal hematoma is discovered , originating from perforation of both common iliac arteries . The lesions and an additional perforation of the ileum were sutured directly . The bullet was excised . The wound healed without complications and the patient recovered completely . The short duration of the rescue chain and the prompt laparotomy with clamping of the aorta are probably what saved this young patient's life . The particular vascular reconstruction in this case , the excision of the bullet , sufficient drainage , and prophylactic administration of antibiotics helped avoid septic complications . Fortunately , it was not a high velocity penetration , which would have demanded a very different treatment . Exact information about the rifle and cartridge , as well as the right strategy in treatment are mandatory for successful management of such dangerous injuries ."
],
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[
0,
1182
]
]
}
] |
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Gefaesschirurgie.90040233.eng.abstr
|
Gefaesschirurgie.90040233.eng.abstr
|
[
{
"id": "Gefaesschirurgie.90040233.eng.abstr-passage-0",
"type": "abstract",
"text": [
"We report on a case of chylous ascites as a rare complication following elective aortic aneurysm repair in a 66-year-old male . After this complication early development on the second postoperative day , relaparotomy was performed with ligation of fistulas and omentumplasty . After recurrence of chylous ascites , conservative treatment for 3 months , including parenteral nutrition and a low-fat diet under continuous peritoneal drainage , finally led to success ."
],
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0,
466
]
]
}
] |
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{
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{
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"id": "Gefaesschirurgie.90040233.eng.abstr-s3-t7",
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[] |
[] |
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] |
HNO.00480018.eng.abstr
|
HNO.00480018.eng.abstr
|
[
{
"id": "HNO.00480018.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Especially after prolonged antibiotic ototopic therapy otomycosis is not rare . An inoculation of fungi into the tympanic cavity however may have serious sequelae . Therefore an eradication of fungi from the external auditory canal is imperative before surgery . In addition to thorough cleaning of the outer ear canal antimycotic preparations are recommended in treating otomycosis . However , all of the commercially available ear drops contain ototoxic agents . In the case of defects of the tympanic membrane a damage of the inner ear may result . Alternatively , we suggest an aqueous solution of Miconazol 0,5% ."
],
"offsets": [
[
0,
618
]
]
}
] |
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{
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217,
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{
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"external auditory canal"
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208,
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"ear"
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309,
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"inner ear"
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}
] |
[] |
[] |
[
{
"id": "HNO.00480018.eng.abstr-s1-r1-t2.1-t1.1",
"type": "uses",
"arg1_id": "HNO.00480018.eng.abstr-s6-t2",
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{
"id": "HNO.00480018.eng.abstr-s2-r1-t4.1-t1.1",
"type": "location_of",
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"arg2_id": "HNO.00480018.eng.abstr-s7-t1",
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},
{
"id": "HNO.00480018.eng.abstr-s2-r2-t3.1-t1.1",
"type": "evaluation_of",
"arg1_id": "HNO.00480018.eng.abstr-s6-t3",
"arg2_id": "HNO.00480018.eng.abstr-s7-t1",
"normalized": []
},
{
"id": "HNO.00480018.eng.abstr-s3-r1-t2.2-t2.1",
"type": "issue_in",
"arg1_id": "HNO.00480018.eng.abstr-s3-t2",
"arg2_id": "HNO.00480018.eng.abstr-s6-t2",
"normalized": []
},
{
"id": "HNO.00480018.eng.abstr-s3-r2-t1.1-t2.1",
"type": "issue_in",
"arg1_id": "HNO.00480018.eng.abstr-s7-t1",
"arg2_id": "HNO.00480018.eng.abstr-s6-t2",
"normalized": []
},
{
"id": "HNO.00480018.eng.abstr-s3-r3-t2.2-t1.1",
"type": "location_of",
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"arg2_id": "HNO.00480018.eng.abstr-s7-t1",
"normalized": []
},
{
"id": "HNO.00480018.eng.abstr-s3-r4-t4.1-t1.1",
"type": "location_of",
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"arg2_id": "HNO.00480018.eng.abstr-s7-t1",
"normalized": []
},
{
"id": "HNO.00480018.eng.abstr-s3-r5-t4.1-t2.1",
"type": "issue_in",
"arg1_id": "HNO.00480018.eng.abstr-s6-t4",
"arg2_id": "HNO.00480018.eng.abstr-s6-t2",
"normalized": []
},
{
"id": "HNO.00480018.eng.abstr-s6-r1-t3.1-t1.1",
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"arg2_id": "HNO.00480018.eng.abstr-s7-t1",
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},
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},
{
"id": "HNO.00480018.eng.abstr-s6-r3-t5.1-t1.1",
"type": "surrounds",
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},
{
"id": "HNO.00480018.eng.abstr-s6-r4-t1.1-t5.1",
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},
{
"id": "HNO.00480018.eng.abstr-s6-r5-t1.1-t3.1",
"type": "developmental_form_of",
"arg1_id": "HNO.00480018.eng.abstr-s7-t1",
"arg2_id": "HNO.00480018.eng.abstr-s6-t3",
"normalized": []
},
{
"id": "HNO.00480018.eng.abstr-s6-r6-t4.1-t1.1",
"type": "surrounds",
"arg1_id": "HNO.00480018.eng.abstr-s6-t4",
"arg2_id": "HNO.00480018.eng.abstr-s7-t1",
"normalized": []
}
] |
HNO.00480022.eng.abstr
|
HNO.00480022.eng.abstr
|
[
{
"id": "HNO.00480022.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Life threatening hemorrhage in patients with malignant tumours of the head and neck area are often , as a result of tumour infiltration , postoperative anatomical changes , infection and radiological necrosis , difficult to control . One option for prophylaxis and treatment is the ligature of the external ( ECA ) or common carotid artery ( CCA ) and superior thyroid artery ( STA ) . 52 patients were examined in a retrospective study to determine both the hazards and the therapeutic use of the procedure . The external carotid artery ( ECA ) was ligated prophylactically during the operative procedure of tumour resection and neck dissection in 25 patients . In 27 cases closure of the ECA , CCA or ECA and STA was carried out as an emergency procedure for acute hemorrhage following completed primary treatment ( operation , primary or postoperative radiation or radiochemotherapy ) . There was no postoperative hemorrhage after prophylactic ligature of the ECA . One patient with multiple cardiovascular diseases suffered from an ipsilateral cerebral infarction 1 year after operation . In 6 of 9 patients and in all 3 patients , in whom ligature of the CCA or ECA and STA respectively was carried out as an emergency procedure , severe neurological complications up to an apallic syndrome occured . The number of deaths due to acute hemorrhage was considerably smaller among those patients with prophylactic ligature of the ECA performed during operative procedure of tumor resection and neck dissection . In addition there were much less unfavourable courses in the sequence of prophylactic closure of the ECA than observed after ligating the CCA or ECA and STA in an emergency situation ."
],
"offsets": [
[
0,
1697
]
]
}
] |
[
{
"id": "HNO.00480022.eng.abstr-s1-t1",
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"text": [
"Life"
],
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4
]
],
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}
]
},
{
"id": "HNO.00480022.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"hemorrhage"
],
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17,
27
]
],
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{
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"db_id": "C0019080"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"patients"
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[
31,
39
]
],
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}
]
},
{
"id": "HNO.00480022.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"malignant"
],
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45,
54
]
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"db_id": "C0006826"
}
]
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{
"id": "HNO.00480022.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"tumours"
],
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]
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"db_id": "C0027651"
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{
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"type": "umlsterm",
"text": [
"head"
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]
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}
]
},
{
"id": "HNO.00480022.eng.abstr-s1-t7",
"type": "umlsterm",
"text": [
"neck"
],
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]
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}
]
},
{
"id": "HNO.00480022.eng.abstr-s1-t8",
"type": "umlsterm",
"text": [
"tumour"
],
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116,
122
]
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}
]
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{
"id": "HNO.00480022.eng.abstr-s1-t9",
"type": "umlsterm",
"text": [
"postoperative"
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138,
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}
]
},
{
"id": "HNO.00480022.eng.abstr-s1-t10",
"type": "umlsterm",
"text": [
"anatomical"
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152,
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"db_id": "C0220784"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s1-t11",
"type": "umlsterm",
"text": [
"infection"
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]
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]
},
{
"id": "HNO.00480022.eng.abstr-s1-t12",
"type": "umlsterm",
"text": [
"necrosis"
],
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]
},
{
"id": "HNO.00480022.eng.abstr-s1-t13",
"type": "umlsterm",
"text": [
"malignant tumours"
],
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45,
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]
],
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"db_id": "C0006826"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"prophylaxis"
],
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"db_id": "C0033107"
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]
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{
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"treatment"
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"db_id": "C0039798"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"ligature"
],
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282,
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]
},
{
"id": "HNO.00480022.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
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}
]
},
{
"id": "HNO.00480022.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"thyroid"
],
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361,
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]
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}
]
},
{
"id": "HNO.00480022.eng.abstr-s2-t6",
"type": "umlsterm",
"text": [
"artery"
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]
],
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}
]
},
{
"id": "HNO.00480022.eng.abstr-s2-t7",
"type": "umlsterm",
"text": [
"carotid artery"
],
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],
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"db_id": "C0162859"
},
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"db_id": "C0007272"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s2-t8",
"type": "umlsterm",
"text": [
"common carotid artery"
],
"offsets": [
[
318,
339
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0162859"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"patients"
],
"offsets": [
[
389,
397
]
],
"normalized": [
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"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"retrospective"
],
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[
417,
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]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0035363"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"therapeutic"
],
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475,
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]
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"db_name": "UMLS",
"db_id": "C0039796"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"use"
],
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}
]
},
{
"id": "HNO.00480022.eng.abstr-s3-t5",
"type": "umlsterm",
"text": [
"procedure"
],
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]
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},
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}
]
},
{
"id": "HNO.00480022.eng.abstr-s3-t6",
"type": "umlsterm",
"text": [
"retrospective study"
],
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417,
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]
],
"normalized": [
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"db_name": "UMLS",
"db_id": "C0035363"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s3-t7",
"type": "umlsterm",
"text": [
"therapeutic use"
],
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[
475,
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]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0039795"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"artery"
],
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[
531,
537
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0003842"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"procedure"
],
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[
596,
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]
],
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"db_id": "C0184661"
},
{
"db_name": "UMLS",
"db_id": "C0025664"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"tumour"
],
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[
609,
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]
],
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{
"db_name": "UMLS",
"db_id": "C0027651"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s4-t4",
"type": "umlsterm",
"text": [
"neck"
],
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[
630,
634
]
],
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{
"db_name": "UMLS",
"db_id": "C0027530"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s4-t5",
"type": "umlsterm",
"text": [
"dissection"
],
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635,
645
]
],
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{
"db_name": "UMLS",
"db_id": "C0012737"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s4-t6",
"type": "umlsterm",
"text": [
"patients"
],
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[
652,
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]
],
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{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s4-t7",
"type": "umlsterm",
"text": [
"carotid artery"
],
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[
523,
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],
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"db_id": "C0162859"
},
{
"db_name": "UMLS",
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}
]
},
{
"id": "HNO.00480022.eng.abstr-s4-t8",
"type": "umlsterm",
"text": [
"operative procedure"
],
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586,
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},
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"db_id": "C0038895"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s4-t9",
"type": "umlsterm",
"text": [
"external carotid artery"
],
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514,
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],
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"db_id": "C0007275"
}
]
},
{
"id": "HNO.00480022.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"emergency"
],
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}
]
},
{
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"procedure"
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}
]
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] |
[] |
[] |
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HNO.00480028.eng.abstr
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HNO.00480028.eng.abstr
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"id": "HNO.00480028.eng.abstr-passage-0",
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"The combined findings of \" normal evoked otoacoustic emissions ( EOAE ) and absent or markedly disturbed auditory evoked potentials from the brainstem and/or cortex \" has been named auditory neuropathy in the English literature . The pure tone thresholds in these patients range from mild to severe loss . The loss of speech comprehension is out of proportion in comparison to the pure tone threshold elevation . This combination of findings suggests that cochlear function and in particular outer hair cell function , is normal in these patients but also suggests that the inner hair cell / VIII nerve functional unit is abnormal . Disruption in neural synchrony has previously been postulated as a reasonable explanation for the absent auditory brainstem response while otoacoustic emissions are preserved . Because the long-latency auditory evoked potentials , not having the stringent synchrony requirements of the ABR , may also be missing , the term synchrony - disruption may be somewhat misleading . The literature about auditory neuropathy is reviewed here : We now know that a set of salient features distinguishes these patients from the majority of patients with sensorineural hearing loss or other described syndromes . The symptoms defining auditory neuropathy are mild , moderate or severe elevation of auditory thresholds to pure tone stimuli by air and bone conduction , absent to severely abnormal ABRs to high level stimuli , present otoacoustic emissions ( that do not suppress with contralateral noise ) , word recognition ability poorer than expected from the pure tone hearing loss configuration ( in cases with mild to moderate hearing threshold elevation ) and absent acoustic reflexes to both ipsilateral and contralateral tones . The entire set of findings , consistently seen in these patients , supports the importance of the crosscheck principle in diagnostic evaluation especially in children with delayed and/or impaired language acquisition . It is of ponderous importance that this disorder is not being confused with sensory hearing loss ."
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HNO.00480033.eng.abstr
|
HNO.00480033.eng.abstr
|
[
{
"id": "HNO.00480033.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Twenty-nine patients ( 26 male and 3 female ) with habitual or obstructive snoring and socially disturbing character were followed over a ten week period . All patients were treated with radiofrequency volumetric tissue reduction ( RFVTR ) of the soft palate . In 21 patients this operation was combined with other surgery of the upper airway , eight patients had soft palate reduction with RFVTR exclusively . With this method an electrode is positioned in the musculatur of the soft palate submucosaly . RFVTR may be performed under local anesthesia and has to be repeated if necessary . Ten weeks postoperatively 24 of 29 patients , respectively their social-partners , reported subjective reduction of snoring after the first treatment . Markable improvement of snoring was seen in 20 of 29 patients postoperatively and reduction of the respiratory-disturbance-index ( RDI ) for more than 10 was noticed in 7/29 patients polysomnographically . 5/8 patients who were treated with RFVTR exclusively , showed reduction of snoring and 3/8 patients had RDI-reduction for more than 10. We conclude , that RFVTR of the soft palate is sucessful in the treatment of snoring and may be helpful in the treatment of mild obstructive-sleep-apnea-syndrome ( OSAS ) ."
],
"offsets": [
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0,
1256
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}
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}
] |
[] |
[] |
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}
] |
HNO.00480041.eng.abstr
|
HNO.00480041.eng.abstr
|
[
{
"id": "HNO.00480041.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Lid retraction in thyroid ophthalmopathy may lead to cosmetic and functional problems . Many surgical procedures are available to correct upper lid retraction . Only those procedures should be used that lead either to a limited lid lengthening or can be reversed in cases with complications . Upper lid gold weight implantation was first used to treat lagophthalmos in patients with facial palsy . Since 1995 only a few reports have appeared which discuss plantinum as an implantation material . We report our experiences with a female patient who developed an upper lid retraction due to thyroid ophthalmopathy . Through implantation of a platinum weight which was adjusted exactly preoperatively , a symmetric palpebral fissure was achieved . Unilateral upper lid retraction with resultant eyelid asymmetry is a new indication for lid loading ."
],
"offsets": [
[
0,
846
]
]
}
] |
[
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],
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18,
25
]
],
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},
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}
]
},
{
"id": "HNO.00480041.eng.abstr-s1-t2",
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],
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[
53,
61
]
],
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}
]
},
{
"id": "HNO.00480041.eng.abstr-s2-t1",
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"surgical"
],
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}
]
},
{
"id": "HNO.00480041.eng.abstr-s2-t2",
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"procedures"
],
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[
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}
]
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{
"id": "HNO.00480041.eng.abstr-s2-t3",
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93,
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]
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{
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}
]
},
{
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172,
182
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}
]
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{
"id": "HNO.00480041.eng.abstr-s3-t2",
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203,
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]
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},
{
"id": "HNO.00480041.eng.abstr-s3-t3",
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],
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[
277,
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]
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}
]
},
{
"id": "HNO.00480041.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"gold"
],
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[
303,
307
]
],
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{
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}
]
},
{
"id": "HNO.00480041.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"weight"
],
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[
308,
314
]
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] |
[] |
[] |
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}
] |
HNO.00480045.eng.abstr
|
HNO.00480045.eng.abstr
|
[
{
"id": "HNO.00480045.eng.abstr-passage-0",
"type": "abstract",
"text": [
"An inflammatory pseudotumor occurs unifocally and is a benign tumor that was initially described in the lung . In the present case report a 24-year-old woman experienced progressive nasal obstruction because of an abnormallity of the nasal septum . A cauliflower-like tumor of the anterior region of the septum cartilage was seen macroscopically and was completely resected . This was diagnosed histologically as an inflammatory pseudotumor . The literature is reviewed and differential diagnoses discussed . Various therapeutic procedures are noted , but the treatment of choice is complete resection of tumor ."
],
"offsets": [
[
0,
612
]
]
}
] |
[
{
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"tumor"
],
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]
],
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}
]
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{
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"lung"
],
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[
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]
],
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}
]
},
{
"id": "HNO.00480045.eng.abstr-s1-t3",
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"inflammatory pseudotumor"
],
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[
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}
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},
{
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"benign tumor"
],
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},
{
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"text": [
"woman"
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{
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},
{
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],
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},
{
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],
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]
},
{
"id": "HNO.00480045.eng.abstr-s3-t1",
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],
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],
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]
},
{
"id": "HNO.00480045.eng.abstr-s3-t2",
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"tumor"
],
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[
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]
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{
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}
]
},
{
"id": "HNO.00480045.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"anterior"
],
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[
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]
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}
]
},
{
"id": "HNO.00480045.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"cartilage"
],
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]
],
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}
]
},
{
"id": "HNO.00480045.eng.abstr-s4-t1",
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] |
[] |
[] |
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}
] |
HNO.00480075.eng.abstr
|
HNO.00480075.eng.abstr
|
[
{
"id": "HNO.00480075.eng.abstr-passage-0",
"type": "abstract",
"text": [
"3D-navigation systems have only recently been introduced into the surgical field . Since then they have gained increasing importance not only in ENT surgery but also in neurosurgery , orthopedic surgery , maxillo-facial surgery , radiology and radiotherapy . Following a brief historical introduction this article reviews existing navigation technologies , in terms of indication , practicability , accuracy , forensic and financial aspects . The selection of the navigation system is strongly influenced by the planned procedure ( endoscopic , microscopic , open approach ) . According to our experience most of these systems provide useful support intraoperatively . The clinical application accuracy regularly lies in the range of 1-2 mm ."
],
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[
0,
742
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]
}
] |
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}
] |
[] |
[] |
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HNO.00480119.eng.abstr
|
HNO.00480119.eng.abstr
|
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"In reconstruction of cartilage defects , autogenous transplantation is known as a reliable and experienced method . Although a clinical application has not been reported until now , tissue engineering permits in vitro production of autogenous cartilage transplants . Nevertheless , in both methods the cartilage is exposed to individually varying resorptive mechanisms . Among other methods for in vivo tissue protection , the encapsulation with a semipermeable polyelectrolytecomplex membrane could guarantee sufficient protection against resorptive influences . Human septal cartilage was encapsulated ( group 1 ) with polyelectrolytecomplex membranes and subcutaneously implanted on the back of thymusaplastic nude mice . Cartilage implants without encapsulation ( group 2 ) were used as control . Scanning electron microscopy and histochemical investigations were performed 1 , 4 , 8 , 12 and 16 weeks after implantation . Group 1 showed no signs of resorption and chronic inflammation at all . In contrast , group 2 presented , correlating to the time of implanta-tion , increasing signs of cell death and fibrotic transformation , representing an increased activity of resorption . In conclusion , tissue encapsulation with a polyelectrolytecomplex membrane could ensure a sufficient protection of human cartilage transplants from resorptive influences . For the plastic-reconstructive surgeon the desired result becomes more calculable ."
],
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] |
[] |
[] |
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] |
HNO.00480129.eng.abstr
|
HNO.00480129.eng.abstr
|
[
{
"id": "HNO.00480129.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Surgical reconstruction of partial defects of the auricle remains an operative challenge . Operative techniques using cartilage frameworks constitute a well established method . According to the localisation and the extend of the defect there are well established procedures . Especially the inferior part of the auricle may cause difficulty due to it's anatomy . In a retrospective study , various reconstruction techniques of partial conchal defects were examined in regard to their aesthetic results . A sytematic operative procedure due to the different techniques was developed . Large defects , extending more than 30% of the concha margin needed a high grade of stability which can be obtained by the use of autologous costal cartilage . According to the localisation of the defect and the available local tissue , the ret-ro-auricular site has to be reconstructed by the use of transposition flaps or split-thickness skin . For the reconstruction of the retroauricular site in the cranial auricular region a combined fascia-fan-flap showed the best results . The inferior auricular region can be reconstructed by the use of an infraauricular transposition flap offering also good opportunities for reconstruction of the lobulus . Second Degree Dysplasias are regarded as conchal defects which can be integrated into surgery ."
],
"offsets": [
[
0,
1333
]
]
}
] |
[
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],
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0,
8
]
],
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}
]
},
{
"id": "HNO.00480129.eng.abstr-s1-t2",
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"defects"
],
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[
35,
42
]
],
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{
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}
]
},
{
"id": "HNO.00480129.eng.abstr-s1-t3",
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"auricle"
],
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[
50,
57
]
],
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},
{
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],
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0,
23
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],
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},
{
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],
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101,
111
]
],
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},
{
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127
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]
},
{
"id": "HNO.00480129.eng.abstr-s3-t1",
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],
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230,
236
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] |
[] |
[] |
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HNO.00480142.eng.abstr
|
HNO.00480142.eng.abstr
|
[
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] |
[] |
[] |
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}
] |
HNO.00480147.eng.abstr
|
HNO.00480147.eng.abstr
|
[
{
"id": "HNO.00480147.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Herpes simplex viruses are known to be among the most common disease-causing microorganisms . Their prevalence can exceed 90% depending on the socioeconomic status of the population . Since the number of immunocompromised patients has increased because of the increased incidence in the acquired immunodeficiency syndrome and an increase in organ transplantation , herpes virus infection may have a greater clinical significance . While treatment of otherwise healthy individuals will not usually cause any clinical problems herpes infection in an immunocompromised patient can have severe consequences . Additionally , development of viral resistance can be observed that may require alternative drugs in treatment . We present a case history of a man with a B-cell chronic lymphocytic leukemia that was associated with a very unusual herpes simplex virus infection in the nasal vestibule . Possible causes for the development of resistance in herpes infections and the use of famciclovir and forscarnet as two therapeutic alternatives to aciclovir are discussed ."
],
"offsets": [
[
0,
1065
]
]
}
] |
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{
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}
] |
[] |
[] |
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"normalized": []
},
{
"id": "HNO.00480147.eng.abstr-s7-r54-t6.1-t7.1",
"type": "diagnoses",
"arg1_id": "HNO.00480147.eng.abstr-s7-t6",
"arg2_id": "HNO.00480147.eng.abstr-s7-t7",
"normalized": []
},
{
"id": "HNO.00480147.eng.abstr-s7-r55-t5.1-t7.1",
"type": "affects",
"arg1_id": "HNO.00480147.eng.abstr-s7-t5",
"arg2_id": "HNO.00480147.eng.abstr-s7-t7",
"normalized": []
},
{
"id": "HNO.00480147.eng.abstr-s7-r56-t6.1-t10.1",
"type": "affects",
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"arg2_id": "HNO.00480147.eng.abstr-s7-t10",
"normalized": []
},
{
"id": "HNO.00480147.eng.abstr-s7-r57-t6.1-t7.1",
"type": "affects",
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"arg2_id": "HNO.00480147.eng.abstr-s7-t7",
"normalized": []
},
{
"id": "HNO.00480147.eng.abstr-s7-r58-t6.1-t9.1",
"type": "interacts_with",
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"arg2_id": "HNO.00480147.eng.abstr-s7-t9",
"normalized": []
},
{
"id": "HNO.00480147.eng.abstr-s7-r59-t1.1-t5.1",
"type": "result_of",
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},
{
"id": "HNO.00480147.eng.abstr-s7-r60-t9.1-t7.1",
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},
{
"id": "HNO.00480147.eng.abstr-s7-r61-t2.1-t1.1",
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},
{
"id": "HNO.00480147.eng.abstr-s7-r62-t8.1-t6.1",
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},
{
"id": "HNO.00480147.eng.abstr-s7-r63-t6.1-t5.1",
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},
{
"id": "HNO.00480147.eng.abstr-s7-r64-t5.1-t2.1",
"type": "measurement_of",
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},
{
"id": "HNO.00480147.eng.abstr-s7-r65-t5.1-t7.1",
"type": "diagnoses",
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"normalized": []
}
] |
HNO.00480170.eng.abstr
|
HNO.00480170.eng.abstr
|
[
{
"id": "HNO.00480170.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Chronic nasal obstruction is a common disorder , mostly caused by hypertrophied inferior turbinates . If there is inadequate response to conservative medical management , the inferior turbinates should be reduced . The choice of treatment is mainly influenced by whether the nasal airway obstruction is due to hypertrophic mucosa or to an enlarged turbinate bone . The first part of this review describes the various surgical modalities for treatment of swelling of the turbinal mucosa . The indications , advantages , disadvantages , complications , and controversies of each modality ( submucous diathermy , cryosurgery , infra-red coagulation , argon-plasma coagulation , radiofrequency , laser surgical techniques ) are reviewed and discussed ."
],
"offsets": [
[
0,
748
]
]
}
] |
[
{
"id": "HNO.00480170.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"disorder"
],
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[
38,
46
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0012634"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"turbinates"
],
"offsets": [
[
89,
99
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0041395"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"nasal obstruction"
],
"offsets": [
[
8,
25
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0027429"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"turbinates"
],
"offsets": [
[
184,
194
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0041395"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"choice"
],
"offsets": [
[
219,
225
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0008300"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"treatment"
],
"offsets": [
[
229,
238
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0087111"
},
{
"db_name": "UMLS",
"db_id": "C0039798"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"hypertrophic"
],
"offsets": [
[
310,
322
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0020564"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"mucosa"
],
"offsets": [
[
323,
329
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0026724"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s3-t5",
"type": "umlsterm",
"text": [
"turbinate"
],
"offsets": [
[
348,
357
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0041395"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s3-t6",
"type": "umlsterm",
"text": [
"bone"
],
"offsets": [
[
358,
362
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0262950"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s3-t7",
"type": "umlsterm",
"text": [
"airway obstruction"
],
"offsets": [
[
281,
299
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0001883"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s3-t8",
"type": "umlsterm",
"text": [
"turbinate bone"
],
"offsets": [
[
348,
362
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0041395"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"review"
],
"offsets": [
[
388,
394
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0282443"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"surgical"
],
"offsets": [
[
417,
425
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0038895"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"treatment"
],
"offsets": [
[
441,
450
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0087111"
},
{
"db_name": "UMLS",
"db_id": "C0039798"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s4-t4",
"type": "umlsterm",
"text": [
"mucosa"
],
"offsets": [
[
479,
485
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0026724"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"complications"
],
"offsets": [
[
535,
548
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0009566"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"diathermy"
],
"offsets": [
[
598,
607
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0012002"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s5-t3",
"type": "umlsterm",
"text": [
"cryosurgery"
],
"offsets": [
[
610,
621
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0010408"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s5-t4",
"type": "umlsterm",
"text": [
"coagulation"
],
"offsets": [
[
634,
645
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0005790"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s5-t5",
"type": "umlsterm",
"text": [
"argon-plasma"
],
"offsets": [
[
648,
660
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0003781"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s5-t6",
"type": "umlsterm",
"text": [
"argon-plasma"
],
"offsets": [
[
648,
660
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0032105"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s5-t7",
"type": "umlsterm",
"text": [
"coagulation"
],
"offsets": [
[
661,
672
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0005790"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s5-t8",
"type": "umlsterm",
"text": [
"laser"
],
"offsets": [
[
692,
697
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0023089"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s5-t9",
"type": "umlsterm",
"text": [
"surgical"
],
"offsets": [
[
698,
706
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0038895"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s5-t10",
"type": "umlsterm",
"text": [
"techniques"
],
"offsets": [
[
707,
717
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0025664"
}
]
},
{
"id": "HNO.00480170.eng.abstr-s5-t11",
"type": "umlsterm",
"text": [
"laser surgical techniques"
],
"offsets": [
[
692,
717
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0023087"
}
]
}
] |
[] |
[] |
[
{
"id": "HNO.00480170.eng.abstr-s1-r1-t2.1-t3.1",
"type": "location_of",
"arg1_id": "HNO.00480170.eng.abstr-s5-t2",
"arg2_id": "HNO.00480170.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s1-r2-t2.1-t1.1",
"type": "location_of",
"arg1_id": "HNO.00480170.eng.abstr-s5-t2",
"arg2_id": "HNO.00480170.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s3-r1-t2.1-t6.1",
"type": "associated_with",
"arg1_id": "HNO.00480170.eng.abstr-s5-t2",
"arg2_id": "HNO.00480170.eng.abstr-s5-t6",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s3-r2-t6.1-t2.1",
"type": "result_of",
"arg1_id": "HNO.00480170.eng.abstr-s5-t6",
"arg2_id": "HNO.00480170.eng.abstr-s5-t2",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s3-r3-t6.1-t4.1",
"type": "produces",
"arg1_id": "HNO.00480170.eng.abstr-s5-t6",
"arg2_id": "HNO.00480170.eng.abstr-s5-t4",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s3-r4-t2.1-t1.1",
"type": "associated_with",
"arg1_id": "HNO.00480170.eng.abstr-s5-t2",
"arg2_id": "HNO.00480170.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s3-r5-t4.1-t2.1",
"type": "location_of",
"arg1_id": "HNO.00480170.eng.abstr-s5-t4",
"arg2_id": "HNO.00480170.eng.abstr-s5-t2",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s3-r6-t6.1-t2.1",
"type": "degree_of",
"arg1_id": "HNO.00480170.eng.abstr-s5-t6",
"arg2_id": "HNO.00480170.eng.abstr-s5-t2",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s3-r7-t2.1-t6.1",
"type": "result_of",
"arg1_id": "HNO.00480170.eng.abstr-s5-t2",
"arg2_id": "HNO.00480170.eng.abstr-s5-t6",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s3-r8-t4.1-t5.1",
"type": "developmental_form_of",
"arg1_id": "HNO.00480170.eng.abstr-s5-t4",
"arg2_id": "HNO.00480170.eng.abstr-s5-t5",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s3-r9-t4.1-t6.1",
"type": "developmental_form_of",
"arg1_id": "HNO.00480170.eng.abstr-s5-t4",
"arg2_id": "HNO.00480170.eng.abstr-s5-t6",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s3-r10-t6.1-t2.1",
"type": "associated_with",
"arg1_id": "HNO.00480170.eng.abstr-s5-t6",
"arg2_id": "HNO.00480170.eng.abstr-s5-t2",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s3-r11-t4.1-t6.1",
"type": "location_of",
"arg1_id": "HNO.00480170.eng.abstr-s5-t4",
"arg2_id": "HNO.00480170.eng.abstr-s5-t6",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s3-r12-t1.1-t6.1",
"type": "associated_with",
"arg1_id": "HNO.00480170.eng.abstr-s5-t1",
"arg2_id": "HNO.00480170.eng.abstr-s5-t6",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s3-r13-t6.1-t1.1",
"type": "associated_with",
"arg1_id": "HNO.00480170.eng.abstr-s5-t6",
"arg2_id": "HNO.00480170.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s3-r14-t2.1-t6.1",
"type": "degree_of",
"arg1_id": "HNO.00480170.eng.abstr-s5-t2",
"arg2_id": "HNO.00480170.eng.abstr-s5-t6",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s3-r15-t4.1-t8.1",
"type": "developmental_form_of",
"arg1_id": "HNO.00480170.eng.abstr-s5-t4",
"arg2_id": "HNO.00480170.eng.abstr-s5-t8",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s3-r16-t1.1-t2.1",
"type": "associated_with",
"arg1_id": "HNO.00480170.eng.abstr-s5-t1",
"arg2_id": "HNO.00480170.eng.abstr-s5-t2",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s4-r1-t1.1-t3.1",
"type": "location_of",
"arg1_id": "HNO.00480170.eng.abstr-s5-t1",
"arg2_id": "HNO.00480170.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s5-r1-t4.1-t9.1",
"type": "method_of",
"arg1_id": "HNO.00480170.eng.abstr-s5-t4",
"arg2_id": "HNO.00480170.eng.abstr-s5-t9",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s5-r2-t1.1-t6.1",
"type": "produces",
"arg1_id": "HNO.00480170.eng.abstr-s5-t1",
"arg2_id": "HNO.00480170.eng.abstr-s5-t6",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s5-r3-t9.1-t8.1",
"type": "uses",
"arg1_id": "HNO.00480170.eng.abstr-s5-t9",
"arg2_id": "HNO.00480170.eng.abstr-s5-t8",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s5-r4-t3.1-t8.1",
"type": "uses",
"arg1_id": "HNO.00480170.eng.abstr-s5-t3",
"arg2_id": "HNO.00480170.eng.abstr-s5-t8",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s5-r5-t1.1-t8.1",
"type": "uses",
"arg1_id": "HNO.00480170.eng.abstr-s5-t1",
"arg2_id": "HNO.00480170.eng.abstr-s5-t8",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s5-r6-t4.1-t1.1",
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"arg1_id": "HNO.00480170.eng.abstr-s5-t4",
"arg2_id": "HNO.00480170.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s5-r7-t7.1-t1.1",
"type": "associated_with",
"arg1_id": "HNO.00480170.eng.abstr-s5-t7",
"arg2_id": "HNO.00480170.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s5-r8-t4.1-t6.1",
"type": "analyzes",
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"arg2_id": "HNO.00480170.eng.abstr-s5-t6",
"normalized": []
},
{
"id": "HNO.00480170.eng.abstr-s5-r9-t5.1-t1.1",
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},
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{
"id": "HNO.00480170.eng.abstr-s5-r25-t4.1-t1.1",
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}
] |
HNO.00480182.eng.abstr
|
HNO.00480182.eng.abstr
|
[
{
"id": "HNO.00480182.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The pathogenetic mechanisms of acute cochleo-vestibular lesions are still unknown , but viral infections and vascular phenomena with impairment of microvascular perfusion are thought to play a major role . Between 1 July , 1986 and 28 February 1998 , 1501 patients were treated with an infusion protocol using cortisone , dextrane 40 and pentoxifylline . Group 1 contained 1001 patients with sudden hearing loss , group 2a 107 patients with isolated tinnitus and group 2b 393 patients with labyrinthine disorders ( among which were 81 patients with cochleovestibular dysfunction ) . The records were evaluated retrospectively . In group 1 complete hearing recovery occurred in 44.8% , partially in 40.4% , no change in 12.1% and worsened in 2.6% . In group 2a with isolated tinnitus 17.9% had a complete recovery , 43.9% partial recovery , 35.5% no change and 2.8% worsened symptoms . In group 2b vertigo disappeared in 56.8% , had partial recovery in 21.0% and did not change in 7.4% . In the 1501 patients treated , no significant side-effects were found to the medical interventions used . From these results we conclude that the infusion protocol is safe and effective in the treatment of cochleo-vestibular disorders ."
],
"offsets": [
[
0,
1223
]
]
}
] |
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{
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{
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]
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{
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{
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{
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{
"id": "HNO.00480182.eng.abstr-s3-t1",
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{
"id": "HNO.00480182.eng.abstr-s3-t4",
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],
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{
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},
{
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{
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]
},
{
"id": "HNO.00480182.eng.abstr-s3-t8",
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},
{
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],
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]
},
{
"id": "HNO.00480182.eng.abstr-s3-t10",
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],
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]
},
{
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],
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{
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}
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},
{
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"hearing"
],
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648,
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}
]
},
{
"id": "HNO.00480182.eng.abstr-s6-t1",
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"tinnitus"
],
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774,
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},
{
"id": "HNO.00480182.eng.abstr-s6-t2",
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],
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]
},
{
"id": "HNO.00480182.eng.abstr-s7-t1",
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"vertigo"
],
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897,
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]
],
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}
]
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{
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{
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]
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{
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],
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1212,
1221
]
],
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{
"db_name": "UMLS",
"db_id": "C0012634"
}
]
}
] |
[] |
[] |
[
{
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"type": "result_of",
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},
{
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},
{
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"arg2_id": "HNO.00480182.eng.abstr-s3-t3",
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},
{
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},
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},
{
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"arg2_id": "HNO.00480182.eng.abstr-s3-t3",
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},
{
"id": "HNO.00480182.eng.abstr-s2-r2-t3.1-t2.1",
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},
{
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},
{
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"arg1_id": "HNO.00480182.eng.abstr-s3-t4",
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"normalized": []
},
{
"id": "HNO.00480182.eng.abstr-s3-r3-t2.1-t11.1",
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},
{
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},
{
"id": "HNO.00480182.eng.abstr-s3-r6-t8.1-t10.1",
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},
{
"id": "HNO.00480182.eng.abstr-s3-r7-t4.1-t10.1",
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},
{
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},
{
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},
{
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},
{
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{
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},
{
"id": "HNO.00480182.eng.abstr-s3-r13-t4.1-t6.1",
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},
{
"id": "HNO.00480182.eng.abstr-s3-r14-t8.1-t2.1",
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"normalized": []
}
] |
HNO.00480189.eng.abstr
|
HNO.00480189.eng.abstr
|
[
{
"id": "HNO.00480189.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The loudness perception of patients with hearing aids was measured with a one-stage category loudness scaling procedure . Data were obtained from 102 ears and were studied primarily in older patients who represented the majority of patients with hearing disorders evaluated in our department . In all , 75% of the patients were older than 45 years and had a mean age of 58 years . The reduction of dynamics at high frequencies was considered to be typical for age-related hearing disorders and was easily quantified with loudness scaling . Findings demonstrated that prediction of recruitment was not possible from pure-tone thresholds or even together with uncomfortable loudness levels , since the slopes of the level-loudness functions revealed a high inter-individual variability . In contrast , the desired compression ratio can be easily calculated with data from the loudness scaling . In this study the loudness perception of patients with mainly non-linear hearing aids fitted with customary procedures was evaluated . The benefit from the hearing aids was proven with the outcome from the loudness scalings , with testing also allowing for a better fitting of the aids ."
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[] |
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] |
HNO.00480195.eng.abstr
|
HNO.00480195.eng.abstr
|
[
{
"id": "HNO.00480195.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Several investigations prove that monaural acoustic deprivation induces detrimental changes in the auditory pathway . So far the major interest focused on degenerative processes on the deprived side , while effects on the contralateral untreated side were not taken into consideration . This ontogenetic study investigates effects of early monaural acoustic deprivation on the functional development of the acoustically evoked auditory brainstem response ( ABR ) in the Mongolian gerbil . Young gerbils were deafened by a single intracochlear application of neomycin sulfate . The ABR development on the contralateral side differed in a late developmental period from that of normally hearing animals . These changes persisted until adulthood . Between day 55 and day 90 a significant 5 dB decrease of the ABR thresholds and a significant shortening of the interpeak latency II-V occured . The results confirm that a complete monaural deprivation during the sensible or critical period leads on the contralateral side to plastic or compensatory changes in the auditory brainstem ."
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[] |
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HNO.00480204.eng.abstr
|
HNO.00480204.eng.abstr
|
[
{
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"The sound transmission properties of three different commercially available middle ear implants and the prototype of a complete middle ear prosthesis ( CoMEP ) were evaluated with a special measurement system that permits standardized conditions . This system uses a mechanical middle ear model ( MMM ) which approximates the impedances of the tympanic membrane and inner ear . The implants were fitted under defined conditions into the MMM . Displacement of the artificial stapes footplate of the MMM was measured with an optical probe . The measurements of different middle ear prostheses showed that the mass of the implant was the most important factor for optimum high frequency transmission . The lightest implant ( 4 mg , titanium ) showed the best results . The CoMEP revealed the highest sensitivity because of a slight enlargement of the diameter of the artificial tympanic membrane . These findings show that the CoMEP is able to restore sound transmission to a normal range . In a second experiment one of the implants was fitted into the MMM with different forces . The increase of stiffness produced a slightly better high frequency transmission at the expense of low frequency sensitivity . Hence , the fitting of the implant may not be too stiff because of its loss of mobility within a significant frequency range ."
],
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0,
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HNO.00480215.eng.abstr
|
HNO.00480215.eng.abstr
|
[
{
"id": "HNO.00480215.eng.abstr-passage-0",
"type": "abstract",
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"Objective : This prospective study reports on the prevalence of hearing impairment in an at-risk neonatal intensive care unit ( NICU ) population ."
],
"offsets": [
[
0,
147
]
]
}
] |
[
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9
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{
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],
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50,
60
]
],
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},
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}
]
},
{
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64,
71
]
],
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116,
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]
],
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]
},
{
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135,
145
]
],
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{
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}
]
},
{
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],
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[
17,
34
]
],
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}
]
},
{
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],
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64,
82
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},
{
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106,
120
]
],
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}
]
},
{
"id": "HNO.00480215.eng.abstr-s1-t9",
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],
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97,
120
]
],
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]
},
{
"id": "HNO.00480215.eng.abstr-s1-t10",
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],
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106,
125
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0021708"
}
]
}
] |
[] |
[] |
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{
"id": "HNO.00480215.eng.abstr-s1-r20-t6.1-t4.1",
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},
{
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},
{
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{
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{
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{
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},
{
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},
{
"id": "HNO.00480215.eng.abstr-s1-r28-t9.1-t3.1",
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"arg2_id": "HNO.00480215.eng.abstr-s1-t3",
"normalized": []
}
] |
HNO.00480221.eng.abstr
|
HNO.00480221.eng.abstr
|
[
{
"id": "HNO.00480221.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Recurrent parotitis is rare in childhood . Its occurrence is characterized by recurrent episodes of swelling and pain in the parotid gland , which are usually accompanied by fever and malaise . Inflammation usually resolves spontaneously during adolescence . The disorder is a condition of unknown etiology . Sialectasis and stricturing occurs in the distal ducts , whereas inflammation of the gland and duct epithelium is probably caused by a low salivary flow rate . Which one can be considered the primary event or secondary change remains unknown . The mainstay of diagnosis is sialography , which depicts typical intraparotidal duct system lesions as strictures or ectasias and excludes sialolithiasis . We here report two 10-year-old male monovular twins who suffered from recurrent swelling and pain in only their left parotid glands . Symptoms were noted approximately every 6 weeks in both patients strictly . Characteristic sialectasis of the distal ducts was demonstrated by magnetic resonance-sialography . Our findings support the hypothesis that recurrent parotitis is caused by a congenital abnormality of the salivary gland ducts . Diagnostic imaging was performed by magnetic resonance imaging during the acute phase of the disease . This technique helps to make the diagnosis without retrograde application of a contrast agent ."
],
"offsets": [
[
0,
1346
]
]
}
] |
[
{
"id": "HNO.00480221.eng.abstr-s1-t1",
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"text": [
"parotitis"
],
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[
10,
19
]
],
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{
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"db_id": "C0030583"
}
]
},
{
"id": "HNO.00480221.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"occurrence"
],
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[
47,
57
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0243132"
}
]
},
{
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}
] |
[] |
[] |
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}
] |
HNO.00480267.eng.abstr
|
HNO.00480267.eng.abstr
|
[
{
"id": "HNO.00480267.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The surgical management of enlarged inferior turbinates has been actively debated for more than a century . The second part of this review decribes the following techniques : laterofracture , submucous turbinectomy , concho-antropexy , partial turbinectomy , anterior turbinectomy , inferior turbinoplasty , total turbinectomy , and vidian neurectomy . Indications , advantages , disadvantages , complications , and controversies of each treatment modalitiy are reviewed and discussed . Partial or submucosal resection should be prefered , because there are moderate side effects and the amount of turbinate excised can be altered according the degree of symptomatology . Total turbinectomy or vidian neurectomy are indicated if all other treatment attemps do not succeed ."
],
"offsets": [
[
0,
773
]
]
}
] |
[
{
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4,
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}
]
},
{
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],
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45,
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]
],
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}
]
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132,
138
]
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}
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},
{
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162,
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},
{
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"complications"
],
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}
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567,
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{
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]
}
] |
[] |
[] |
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}
] |
HNO.00480275.eng.abstr
|
HNO.00480275.eng.abstr
|
[
{
"id": "HNO.00480275.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Facial neuromyography is an objective electrophysiologic measurement used to assess prognosis for recovery from facial paralysis . In the present study variability over time of the amplitude ratio in healthy subjects was investigated . Twenty healthy subjects underwent four neuromyographic tests at intervals of one week . The study group consisted of 12 males and 8 females . Ages ranged from 23 to 36 years . The stimulation intensity required for supramaximal stimulation was 14.6 mA on average . The mean of the intra-individual side-to-side difference of the evoked compound action potential was 32.5% . Results of the four repeated tests ranged from no to 80% side-to-side differences in the same individual . The hypothesis of symmetrical evoked facial compound potentials was not supported by our data . As with previous investigators we found significant side-to-side differences in healthy subjects . Furthermore , we could also show for the first time that the amplitude ratio was not constant in every individual at repeated measurements . We conclude that there is a physiological variability that must be taken into account in the interpretation of facial nerve neuromyography ."
],
"offsets": [
[
0,
1193
]
]
}
] |
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7,
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{
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"objective"
],
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]
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}
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"measurement"
],
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57,
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]
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}
]
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{
"id": "HNO.00480275.eng.abstr-s1-t5",
"type": "umlsterm",
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"paralysis"
],
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[
119,
128
]
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"db_id": "C0030440"
}
]
},
{
"id": "HNO.00480275.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"facial paralysis"
],
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[
112,
128
]
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"time"
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169,
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],
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}
]
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"id": "HNO.00480275.eng.abstr-s4-t1",
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"males"
],
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356,
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]
],
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"db_id": "C0024554"
},
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}
]
},
{
"id": "HNO.00480275.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"females"
],
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368,
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]
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}
]
},
{
"id": "HNO.00480275.eng.abstr-s5-t1",
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"Ages"
],
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378,
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]
],
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},
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}
]
},
{
"id": "HNO.00480275.eng.abstr-s7-t1",
"type": "umlsterm",
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"action potential"
],
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]
],
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}
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{
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],
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]
},
{
"id": "HNO.00480275.eng.abstr-s11-t1",
"type": "umlsterm",
"text": [
"time"
],
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}
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},
{
"id": "HNO.00480275.eng.abstr-s11-t2",
"type": "umlsterm",
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"measurements"
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1038,
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]
},
{
"id": "HNO.00480275.eng.abstr-s12-t1",
"type": "umlsterm",
"text": [
"nerve"
],
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1171,
1176
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[] |
[] |
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HNO.00480281.eng.abstr
|
HNO.00480281.eng.abstr
|
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[] |
[] |
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HNO.00480287.eng.abstr
|
HNO.00480287.eng.abstr
|
[
{
"id": "HNO.00480287.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The benefit of innovative hearing aid technology can be evaluated in clinical trials . The present study describes the comparison of a new digital hearing aid with an analogue device serving as a reference . The tests were carried out with 15 experienced hearing aid wearers . To prevent the influence of different fitting algorithms such as prescriptive or loudness-based the digital devices were not renewed fitted but their level- and frequency-depending gain was adjusted to that of the reference . Different tests concerning loudness perception ( category loudness scaling ) speech discrimination in noise ( the Goettingen sentence test ) and self-assessment of the benefit by questionnaires were performed . All tests yielded slightly better results for the digital hearing aid . The speech audiometric evaluation showed somewhat better discrimination for the test-device . The questionnaires yielded a marked preference for the digital device . Because the study was not blinded influences due to the knowledge of the subjects of testing a new technology generally can occur . On the other hand , the question arises whether present audiometric tests sufficiently consider signal processing of modern hearing systems . Furthermore , one has to take into account that only a few of the features of digital technology such as noise-reduction and feedback-cancellation were considered in this study to allow for a sensible comparison . Because of the large number of possibilities offered by digital technology additional benefit by the hearing aid can be expected ."
],
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0,
1570
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}
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] |
HNO.00480302.eng.abstr
|
HNO.00480302.eng.abstr
|
[
{
"id": "HNO.00480302.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Oral appliances are used to treat snoring and sleep apnea . Yet , their success cannot be predicted without a therapeutical trial . This uncertainty and the high prices of the appliances are the reasons for their limited use . We tested a cheap , custom fit mandibular advancement device ( SnorBan ) for the treatment of sleep disordered breathing in order to assess its efficacy . 39 consecutive patients ( 51,1 +/- 9,2 years , BMI = 27,4 +/- 4,5 kg/m2) with different degrees of sleep disordered breathing ( AHI = 16,6/h +/- 15,6/h) received the device after a thorough clinical examination . After getting used to the device a second polysomnography was performed . The AHI improved significantly from 16,6/h to 8,2/h ( p 0,01 ) in the whole group . The only patient who became worse could not get used to the device . Time with snoring dropped significantly from 16,3% to 6,6% . 59,1% of the sleep apnea patients were successfully treated as their RDI dropped below 10/h. The sleep efficiency remained unchanged . Slow wave sleep and REM-sleep increased significantly from 12% to 16% ( p 0,05 ) . The overall compliance was 75% . The custom fit mandibular advancement device Snorban is a cheap and effective treatment for a number of patients with snoring and sleep apnea . The oral appliance is proven to be a useful and simple , non-surgical treatment option . Polysomnographic follow-up is mandatory as breathing may worsen with the device while asleep ."
],
"offsets": [
[
0,
1461
]
]
}
] |
[
{
"id": "HNO.00480302.eng.abstr-s1-t1",
"type": "umlsterm",
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"appliances"
],
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[
5,
15
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0243112"
}
]
},
{
"id": "HNO.00480302.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"sleep"
],
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[
46,
51
]
],
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] |
[] |
[] |
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},
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"id": "HNO.00480302.eng.abstr-s13-r40-t7.1-t8.1",
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"normalized": []
}
] |
HNO.00480309.eng.abstr
|
HNO.00480309.eng.abstr
|
[
{
"id": "HNO.00480309.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Background : Having one or 2 hearing aids is not a guarantee that a child will wear the instruments constantly . The purpose of this study was to evaluate the hearing aid acceptance by children ( assessed using the daily wearing time ) ."
],
"offsets": [
[
0,
237
]
]
}
] |
[
{
"id": "HNO.00480309.eng.abstr-s1-t1",
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"text": [
"hearing"
],
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[
29,
36
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0018767"
}
]
},
{
"id": "HNO.00480309.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"aids"
],
"offsets": [
[
37,
41
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0021588"
},
{
"db_name": "UMLS",
"db_id": "C0001175"
}
]
},
{
"id": "HNO.00480309.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"child"
],
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[
68,
73
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0008059"
}
]
},
{
"id": "HNO.00480309.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"instruments"
],
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[
88,
99
]
],
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{
"db_name": "UMLS",
"db_id": "C0243113"
}
]
},
{
"id": "HNO.00480309.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"hearing aids"
],
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[
29,
41
]
],
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{
"db_name": "UMLS",
"db_id": "C0018768"
}
]
},
{
"id": "HNO.00480309.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"hearing"
],
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[
159,
166
]
],
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{
"db_name": "UMLS",
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}
]
},
{
"id": "HNO.00480309.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"aid"
],
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167,
170
]
],
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},
{
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}
]
},
{
"id": "HNO.00480309.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"children"
],
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[
185,
193
]
],
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{
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}
]
},
{
"id": "HNO.00480309.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"time"
],
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[
229,
233
]
],
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{
"db_name": "UMLS",
"db_id": "C0040223"
}
]
},
{
"id": "HNO.00480309.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"hearing aid"
],
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[
159,
170
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0018768"
}
]
}
] |
[] |
[] |
[
{
"id": "HNO.00480309.eng.abstr-s1-r1-t1.1-t2.2",
"type": "result_of",
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},
{
"id": "HNO.00480309.eng.abstr-s1-r3-t2.1-t4.1",
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"arg2_id": "HNO.00480309.eng.abstr-s2-t4",
"normalized": []
},
{
"id": "HNO.00480309.eng.abstr-s1-r4-t3.1-t4.1",
"type": "uses",
"arg1_id": "HNO.00480309.eng.abstr-s2-t3",
"arg2_id": "HNO.00480309.eng.abstr-s2-t4",
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},
{
"id": "HNO.00480309.eng.abstr-s1-r6-t2.2-t3.1",
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"arg2_id": "HNO.00480309.eng.abstr-s2-t3",
"normalized": []
},
{
"id": "HNO.00480309.eng.abstr-s1-r7-t1.1-t3.1",
"type": "produces",
"arg1_id": "HNO.00480309.eng.abstr-s2-t1",
"arg2_id": "HNO.00480309.eng.abstr-s2-t3",
"normalized": []
},
{
"id": "HNO.00480309.eng.abstr-s1-r8-t2.2-t1.1",
"type": "result_of",
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},
{
"id": "HNO.00480309.eng.abstr-s1-r9-t3.1-t2.1",
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"normalized": []
},
{
"id": "HNO.00480309.eng.abstr-s1-r10-t4.1-t2.2",
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},
{
"id": "HNO.00480309.eng.abstr-s1-r11-t2.1-t1.1",
"type": "affects",
"arg1_id": "HNO.00480309.eng.abstr-s2-t2",
"arg2_id": "HNO.00480309.eng.abstr-s2-t1",
"normalized": []
},
{
"id": "HNO.00480309.eng.abstr-s1-r12-t4.1-t2.2",
"type": "treats",
"arg1_id": "HNO.00480309.eng.abstr-s2-t4",
"arg2_id": "HNO.00480309.eng.abstr-s2-t2",
"normalized": []
},
{
"id": "HNO.00480309.eng.abstr-s2-r1-t5.1-t2.2",
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},
{
"id": "HNO.00480309.eng.abstr-s2-r2-t1.1-t2.2",
"type": "result_of",
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},
{
"id": "HNO.00480309.eng.abstr-s2-r4-t4.1-t1.1",
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},
{
"id": "HNO.00480309.eng.abstr-s2-r6-t2.1-t5.1",
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},
{
"id": "HNO.00480309.eng.abstr-s2-r7-t3.1-t5.1",
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},
{
"id": "HNO.00480309.eng.abstr-s2-r8-t2.2-t3.1",
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"id": "HNO.00480309.eng.abstr-s2-r9-t1.1-t4.1",
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{
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{
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"normalized": []
},
{
"id": "HNO.00480309.eng.abstr-s2-r12-t2.2-t1.1",
"type": "result_of",
"arg1_id": "HNO.00480309.eng.abstr-s2-t2",
"arg2_id": "HNO.00480309.eng.abstr-s2-t1",
"normalized": []
},
{
"id": "HNO.00480309.eng.abstr-s2-r13-t2.1-t1.1",
"type": "affects",
"arg1_id": "HNO.00480309.eng.abstr-s2-t2",
"arg2_id": "HNO.00480309.eng.abstr-s2-t1",
"normalized": []
}
] |
HNO.00480318.eng.abstr
|
HNO.00480318.eng.abstr
|
[
{
"id": "HNO.00480318.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The monomorphic clinical aspect of destructive mid-face lesions is characterised by inflammation , induration and granulomatous transformation . This feature can be caused by various infections , toxical noxa , Wegener's Granulomatosis and different neoplasms . The case of a 19 year old patient with EBV associated nasal type T-cell lymphoma located at the hard palate is presented . The diagnostic approach and difficulties in diagnosing this entity assessing by using multiple biopsies , serological and molecularbiological detection of EBV association and immunohistochemistry for atypic T-cells are elucidated . In the presented case the treatment with chemotherapy and irradiation following a well-defined therapy concept leaded to a three year recurrence-free survival so far . The comparison of the key-histological findings and the major differential diagnoses is mandatory to establish the final diagnosis of lymphoma . This is the basement for treating this disease with combined chemotherapy and irradiation for optimizing survival ."
],
"offsets": [
[
0,
1045
]
]
}
] |
[
{
"id": "HNO.00480318.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"inflammation"
],
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[
84,
96
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0021368"
}
]
},
{
"id": "HNO.00480318.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"infections"
],
"offsets": [
[
183,
193
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0021311"
}
]
},
{
"id": "HNO.00480318.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"noxa"
],
"offsets": [
[
204,
208
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0028470"
}
]
},
{
"id": "HNO.00480318.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"Granulomatosis"
],
"offsets": [
[
221,
235
]
],
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{
"db_name": "UMLS",
"db_id": "C0018188"
}
]
},
{
"id": "HNO.00480318.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"Granulomatosis"
],
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[
221,
235
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0751995"
}
]
},
{
"id": "HNO.00480318.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"neoplasms"
],
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[
250,
259
]
],
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{
"db_name": "UMLS",
"db_id": "C0027651"
},
{
"db_name": "UMLS",
"db_id": "C0036210"
}
]
},
{
"id": "HNO.00480318.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"old"
],
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[
284,
287
]
],
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{
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"db_id": "C0331059"
}
]
},
{
"id": "HNO.00480318.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"patient"
],
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[
288,
295
]
],
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{
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"db_id": "C0030705"
}
]
},
{
"id": "HNO.00480318.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"EBV"
],
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[
301,
304
]
],
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{
"db_name": "UMLS",
"db_id": "C0014644"
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] |
[] |
[] |
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HNO.00480346.eng.abstr
|
HNO.00480346.eng.abstr
|
[
{
"id": "HNO.00480346.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Motion sickness is a well know nausea and vomiting syndrom whose physical signs occur during travel by sea , automobile , airplane , and space . This review describes current concepts concerning the aetiology , nature and therapy of this common phenomenon . Motion sickness involve a neural mismatch or confusion between the vestibular , visual , and proporioceptive systems . Therapy is directed towards decreasing conflicting sensory input , controlling nausea , and speeding the process of adaptation ."
],
"offsets": [
[
0,
505
]
]
}
] |
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6
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{
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],
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42,
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}
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"signs"
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74,
79
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{
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"travel"
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{
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109,
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}
]
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{
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],
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199,
208
]
],
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}
]
},
{
"id": "HNO.00480346.eng.abstr-s2-t3",
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211,
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] |
[] |
[] |
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},
{
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}
] |
HNO.00480361.eng.abstr
|
HNO.00480361.eng.abstr
|
[
{
"id": "HNO.00480361.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The osteoplastic frontal sinus surgery with obliteration of the sinus has been established in the therapy of frontal sinus diseases that can not be drainaged permanently or healed through an endonasal access . The obliteration of the frontal sinus is endangered in cases of multiple fracturing of the posterior frontal sinus wall or if it has been destroyed by an inflammatory process . In these problematic cases obliteration bears the danger of complications and cranialization of the frontal sinus is therefore the method of choice . We review 8 patients who were operated on using the cranialization technique . Indications for surgery were a combined fracture of the anterior and posterior frontal sinus wall ( 3 ) , a pyocele of the front sinus with extensive destruction of the posterior wall ( 4 ) and a large osteoma of the posterior frontal sinus wall ( 1 ) . The frontal sinus was exposed through a coronal incision , the mucosa and the posterior wall were completely removed and the frontal sinus obliterated with fat tissue . The anterior sinus wall was replaced after obliteration of the sinus or reconstructed with calvarian bone transplants . The follow up period was 1.8 years ( 11 months to 8 years ) . All patients underwent postoperatively a clinical ENT-examination and radiological assessment by CT-scan or MRI . The overall functional and esthetic outcome was excellent . There were no serious complications nor any recurrence . The cranialization of the frontal sinus is a reliable and safe variation of the classical osteoplastic frontal sinus surgery with fat obliteration ."
],
"offsets": [
[
0,
1600
]
]
}
] |
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"sinus"
],
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25,
30
]
],
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]
},
{
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"surgery"
],
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31,
38
]
],
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]
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{
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64,
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98,
105
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]
},
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117,
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] |
[] |
[] |
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] |
HNO.00480372.eng.abstr
|
HNO.00480372.eng.abstr
|
[
{
"id": "HNO.00480372.eng.abstr-passage-0",
"type": "abstract",
"text": [
"After exstirpation of an acoustic neuroma one trends to concentrated on the preservation of hearing and facial function . But how does the surgical removal for an acoustic neuroma , influence the symptoms of tinnitus and vertigo ? Our report follows a retrospective evaluation of 78 patients . Based on these results we will also discuss aspects of the origin of these symptoms . Our patients suffered from tinnitus at a rate of 73% preoperatively and 59% postoperatively . With increasing tumor size tinnitus occurred less often , therefore we considered the size of the tumor exclusively . Also , an intraoperative dissection of the cochlear nerve often did not result in an improvement of the symptoms . Vertigo was stated prooperatively in 44% of the cases , postoperatively in 22% . Again as with tinnitus , there was an inverse relationship between the size of the tumor and the severity of the symptoms . In conclusion a deafferention-like syndrome has to be considered as the major causative factor for the tinnitus in patients with acoustic neuromas . However , in the vertigo cases , the symptoms seem to be caused vestibularily due to the increasing tumor and then after a temporary compensation a cerebellar ataxia occured which the patients often perceive as vertigo ."
],
"offsets": [
[
0,
1281
]
]
}
] |
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33
]
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{
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],
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41
]
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],
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46,
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],
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{
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{
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] |
[] |
[] |
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] |
HNO.00480378.eng.abstr
|
HNO.00480378.eng.abstr
|
[
{
"id": "HNO.00480378.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The influence of the time delay of a nerve suture on axonal regeneration after nerve lesion is still unknown . We used the rat as an animal model and studied the influence of a 14- and 224-day delayed hypoglossal-facial nerve anastomosis ( HFA ) and compared results to immediate HFA . After injection of horseradish peroxidase into the whiskerpad we counted the retrogradely labelled neurons in the hypoglossal nucleus 7-112 days after operation to quantify the axonal reinnervation . Additionally , the amplitude of the evoked compound action potential of the whiskerpad was measured after hypoglossal nerve stimulation . By 112 days after immediate HFA only 931 +/- 27 hypoglossal neurons reinnervated the muscle ( for 75% of normal innervation ) . After 14 days delayed HFA reinnervation was accelerated and enhanced with 1293 +/- 81 ( 104% ) neurons . Even after 224 days delayed HFA reinnervation was possible , with 760 +/- 80 neurons ( 61% ) present . We conclude that short-term delayed nerve suture improves axonal reinnervation ."
],
"offsets": [
[
0,
1040
]
]
}
] |
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] |
[] |
[] |
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HNO.00480383.eng.abstr
|
HNO.00480383.eng.abstr
|
[
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"type": "abstract",
"text": [
"Sound overexposure is known to cause damage to cochlear structures and can induce permanent or temporary hearing loss and tinnitus . Perhaps the most sensitive of these structures to sound overexposure are the tip links . In this paper the elecrophysiological effects of pharmacological destruction of the tip links of outer hair cells was investigated . Outer hair cells treated with elastase ( 20 U/mL ) or BAPTA ( 5 mM ) no longer responded to sinusoidal stimuli . In contrast to common belief , transduction channels opened due to loss of tip links . Such opened channels can allow K+ and Ca2+ to enter the cell from the endolymphatic space and could lead to permanent depolarization . This influx of cations caused by loss of tip links , together with the subsequent hair-cell depolarization , might be a source of sensorineural hearing loss and tinnitus associated with acoustic trauma ."
],
"offsets": [
[
0,
893
]
]
}
] |
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] |
[] |
[] |
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HNO.00480390.eng.abstr
|
HNO.00480390.eng.abstr
|
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],
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0,
414
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] |
HNO.00480394.eng.abstr
|
HNO.00480394.eng.abstr
|
[
{
"id": "HNO.00480394.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The carcinoid tumor of the middle ear is a very rare neoplasm which in general is regarded as benign but may be mistaken for an adenocarcinoma because of its histological heterogeneity . Typical , however , is its neuroendocrine and mucinous differentiation so that an unequivocal diagnosis is possible by means of immunohistochemistry and electron microscopy . As the tumor is very rare , there is no statistical evidence as to whether further treatment is necessary after primary exstirpation of the tumor . Therefore , a review of the literature was performed . We report about a 28-year-old male patient with a carcinoid tumor of the left tympanic cavity . Without any further treatment there has been no evidence for either recurrence or metastases 32 months after surgical resection . As treatment of choice we recommend conservative surgery with complete removal of the tumor and a clinical follow-up on a regular basis ."
],
"offsets": [
[
0,
928
]
]
}
] |
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HNO.00480430.eng.abstr
|
HNO.00480430.eng.abstr
|
[
{
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"type": "abstract",
"text": [
"Successful use of non-biologic implants in reconstructive head and neck surgery is dependent on tissue compatibility and epithelization . This is true not only for epithelial cells , but also for mesenchymatic cells . Therefore we tested several substrates with human fibroblasts or keratinocytes from the oral mucosa in cell culture . In tissue culture keratinocyte outgrowth from small mucosal flaps onto the surface was observed . Preparations were evaluated by histology and scanning electron microscopy . Cellulose-ester , polyvinylidene-difluoride and polyglactin developed monolayers of fibroblasts and keratinocytes in cell cultures . In tissue culture mucosal flaps showed good adherence to the surface of these materials and a fine outgrowth of keratinocytes . Expanded polytetrafluor-ethylene ( ePTFE ) was partially covered by a layer of fibroblasts and keratinocytes in cell culture , but cell adherence was not sufficient . In tissue culture the mucosal flaps failed to attach on ePTFE . These results illustrate that the mesenchymatic and epithelial component of cell and tissue cultures show different qualities of cellular adherence and growth on the surface of non-biologic implants . We propose our method for the development of an in-vitro model for the epithelization of non-biologic implantation materials ."
],
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[
0,
1329
]
]
}
] |
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"id": "HNO.00480430.eng.abstr-s10-r49-t6.2-t8.1",
"type": "interacts_with",
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"arg2_id": "HNO.00480430.eng.abstr-s10-t8",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s10-r50-t8.1-t2.2",
"type": "affects",
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"arg2_id": "HNO.00480430.eng.abstr-s11-t2",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s10-r51-t2.2-t6.2",
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"arg2_id": "HNO.00480430.eng.abstr-s10-t6",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s10-r52-t3.1-t9.1",
"type": "location_of",
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"arg2_id": "HNO.00480430.eng.abstr-s10-t9",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s10-r53-t8.1-t6.1",
"type": "affects",
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"arg2_id": "HNO.00480430.eng.abstr-s10-t6",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s10-r54-t3.1-t2.2",
"type": "location_of",
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"arg2_id": "HNO.00480430.eng.abstr-s11-t2",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s11-r1-t2.1-t3.1",
"type": "produces",
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"arg2_id": "HNO.00480430.eng.abstr-s11-t3",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s11-r2-t2.1-t4.1",
"type": "result_of",
"arg1_id": "HNO.00480430.eng.abstr-s11-t2",
"arg2_id": "HNO.00480430.eng.abstr-s11-t4",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s11-r3-t4.1-t1.2",
"type": "degree_of",
"arg1_id": "HNO.00480430.eng.abstr-s11-t4",
"arg2_id": "HNO.00480430.eng.abstr-s11-t1",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s11-r4-t3.1-t4.1",
"type": "affects",
"arg1_id": "HNO.00480430.eng.abstr-s11-t3",
"arg2_id": "HNO.00480430.eng.abstr-s11-t4",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s11-r5-t4.1-t3.1",
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"arg2_id": "HNO.00480430.eng.abstr-s11-t3",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s11-r6-t1.1-t4.1",
"type": "measurement_of",
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"arg2_id": "HNO.00480430.eng.abstr-s11-t4",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s11-r7-t1.1-t2.1",
"type": "measurement_of",
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"arg2_id": "HNO.00480430.eng.abstr-s11-t2",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s11-r8-t3.1-t2.1",
"type": "affects",
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"arg2_id": "HNO.00480430.eng.abstr-s11-t2",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s11-r9-t4.1-t2.1",
"type": "result_of",
"arg1_id": "HNO.00480430.eng.abstr-s11-t4",
"arg2_id": "HNO.00480430.eng.abstr-s11-t2",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s11-r10-t1.2-t3.1",
"type": "produces",
"arg1_id": "HNO.00480430.eng.abstr-s11-t1",
"arg2_id": "HNO.00480430.eng.abstr-s11-t3",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s11-r11-t2.1-t1.1",
"type": "affects",
"arg1_id": "HNO.00480430.eng.abstr-s11-t2",
"arg2_id": "HNO.00480430.eng.abstr-s11-t1",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s11-r12-t1.2-t4.1",
"type": "result_of",
"arg1_id": "HNO.00480430.eng.abstr-s11-t1",
"arg2_id": "HNO.00480430.eng.abstr-s11-t4",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s11-r13-t4.1-t1.1",
"type": "affects",
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"arg2_id": "HNO.00480430.eng.abstr-s11-t1",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s11-r14-t1.2-t4.1",
"type": "degree_of",
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"arg2_id": "HNO.00480430.eng.abstr-s11-t4",
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},
{
"id": "HNO.00480430.eng.abstr-s11-r15-t1.2-t2.1",
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},
{
"id": "HNO.00480430.eng.abstr-s11-r16-t2.1-t1.2",
"type": "result_of",
"arg1_id": "HNO.00480430.eng.abstr-s11-t2",
"arg2_id": "HNO.00480430.eng.abstr-s11-t1",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s11-r18-t3.1-t1.2",
"type": "affects",
"arg1_id": "HNO.00480430.eng.abstr-s11-t3",
"arg2_id": "HNO.00480430.eng.abstr-s11-t1",
"normalized": []
},
{
"id": "HNO.00480430.eng.abstr-s11-r19-t4.1-t1.2",
"type": "result_of",
"arg1_id": "HNO.00480430.eng.abstr-s11-t4",
"arg2_id": "HNO.00480430.eng.abstr-s11-t1",
"normalized": []
}
] |
HNO.00480436.eng.abstr
|
HNO.00480436.eng.abstr
|
[
{
"id": "HNO.00480436.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Objective : Olfactory dysfunction is a common finding in patients with chronic rhinosinusitis ( CRS ) . The aim of this study was to investigate the relationship between olfaction and nasal flow as determined by active anterior rhinomanometry ( AAR ) ."
],
"offsets": [
[
0,
252
]
]
}
] |
[
{
"id": "HNO.00480436.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"Objective"
],
"offsets": [
[
0,
9
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0018017"
}
]
},
{
"id": "HNO.00480436.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"dysfunction"
],
"offsets": [
[
22,
33
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0031847"
}
]
},
{
"id": "HNO.00480436.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"finding"
],
"offsets": [
[
46,
53
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0243095"
}
]
},
{
"id": "HNO.00480436.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"patients"
],
"offsets": [
[
57,
65
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "HNO.00480436.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"aim"
],
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[
108,
111
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0108800"
}
]
},
{
"id": "HNO.00480436.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"olfaction"
],
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[
170,
179
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0037361"
}
]
},
{
"id": "HNO.00480436.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"anterior"
],
"offsets": [
[
219,
227
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0032008"
}
]
},
{
"id": "HNO.00480436.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"rhinomanometry"
],
"offsets": [
[
228,
242
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0024751"
}
]
}
] |
[] |
[] |
[
{
"id": "HNO.00480436.eng.abstr-s1-r1-t2.1-t1.1",
"type": "uses",
"arg1_id": "HNO.00480436.eng.abstr-s2-t2",
"arg2_id": "HNO.00480436.eng.abstr-s2-t1",
"normalized": []
},
{
"id": "HNO.00480436.eng.abstr-s2-r1-t4.1-t1.1",
"type": "analyzes",
"arg1_id": "HNO.00480436.eng.abstr-s2-t4",
"arg2_id": "HNO.00480436.eng.abstr-s2-t1",
"normalized": []
},
{
"id": "HNO.00480436.eng.abstr-s2-r2-t4.1-t1.1",
"type": "assesses_effect_of",
"arg1_id": "HNO.00480436.eng.abstr-s2-t4",
"arg2_id": "HNO.00480436.eng.abstr-s2-t1",
"normalized": []
},
{
"id": "HNO.00480436.eng.abstr-s2-r3-t1.1-t3.1",
"type": "disrupts",
"arg1_id": "HNO.00480436.eng.abstr-s2-t1",
"arg2_id": "HNO.00480436.eng.abstr-s2-t3",
"normalized": []
},
{
"id": "HNO.00480436.eng.abstr-s2-r4-t3.1-t1.1",
"type": "location_of",
"arg1_id": "HNO.00480436.eng.abstr-s2-t3",
"arg2_id": "HNO.00480436.eng.abstr-s2-t1",
"normalized": []
},
{
"id": "HNO.00480436.eng.abstr-s2-r5-t3.1-t1.1",
"type": "produces",
"arg1_id": "HNO.00480436.eng.abstr-s2-t3",
"arg2_id": "HNO.00480436.eng.abstr-s2-t1",
"normalized": []
}
] |
HNO.00480444.eng.abstr
|
HNO.00480444.eng.abstr
|
[
{
"id": "HNO.00480444.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A lot of different endogenous and exogenous factors are accused to promote squamous cell carcinomas in the upper aerodigestive tract . Main risk factors are the chronic tobacco- and alkohol consumption . The fact , that many patients develop syn- or metachronic carcinomas in this area was first described by Slaughter et al. 1953 and explained with the phenomenon of field cancerisation . Concerning to this hypothesis the whole mucosa of the upper aerodigestive-tract is premalignant damaged . In our study the micronucleus-frequency was determined as a biomarker for the genetic injury to prove the fieldcancerisation on the cellular level at 159 people ( control-group , abuser , patients with HNSCC ) . Our results confirm the hypothesis of fieldcancerisation of the mucosa of the upper aerodigestiv-tract at strong tobacco- and alkohol consumers and patients with head and neck squamous cell carcinoma . Furthermore there is a highly statistically significant correlation between increasing micronucleus frequency and increasing tobacco abuse . As a final result of our study the micronucleus assay seems to be of good value to show a genotoxic damage in healthy mucosa at people with a high risk to develop HNSCC , but it's not usable to give any answer if and when such carcinomas arise ."
],
"offsets": [
[
0,
1296
]
]
}
] |
[
{
"id": "HNO.00480444.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"cell"
],
"offsets": [
[
84,
88
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0007634"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"carcinomas"
],
"offsets": [
[
89,
99
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0007097"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"squamous cell carcinomas"
],
"offsets": [
[
75,
99
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0007137"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"risk"
],
"offsets": [
[
140,
144
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0035647"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"tobacco-"
],
"offsets": [
[
169,
177
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0040329"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"consumption"
],
"offsets": [
[
190,
201
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0009830"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"risk factors"
],
"offsets": [
[
140,
152
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0035648"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"patients"
],
"offsets": [
[
225,
233
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"metachronic"
],
"offsets": [
[
250,
261
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0025646"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"carcinomas"
],
"offsets": [
[
262,
272
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0007097"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"mucosa"
],
"offsets": [
[
430,
436
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0026724"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"premalignant"
],
"offsets": [
[
473,
485
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0032927"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"micronucleus-frequency"
],
"offsets": [
[
513,
535
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0026004"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"micronucleus-frequency"
],
"offsets": [
[
513,
535
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0376249"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s5-t3",
"type": "umlsterm",
"text": [
"biomarker"
],
"offsets": [
[
556,
565
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0005516"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s5-t4",
"type": "umlsterm",
"text": [
"injury"
],
"offsets": [
[
582,
588
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0175677"
},
{
"db_name": "UMLS",
"db_id": "C0021501"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s5-t5",
"type": "umlsterm",
"text": [
"people"
],
"offsets": [
[
650,
656
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0027361"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s5-t6",
"type": "umlsterm",
"text": [
"control-group"
],
"offsets": [
[
659,
672
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0243148"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s5-t7",
"type": "umlsterm",
"text": [
"patients"
],
"offsets": [
[
684,
692
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s6-t1",
"type": "umlsterm",
"text": [
"mucosa"
],
"offsets": [
[
772,
778
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0026724"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s6-t2",
"type": "umlsterm",
"text": [
"tobacco-"
],
"offsets": [
[
821,
829
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0040329"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s6-t3",
"type": "umlsterm",
"text": [
"patients"
],
"offsets": [
[
856,
864
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s6-t4",
"type": "umlsterm",
"text": [
"head"
],
"offsets": [
[
870,
874
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0018670"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s6-t5",
"type": "umlsterm",
"text": [
"neck"
],
"offsets": [
[
879,
883
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0027530"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s6-t6",
"type": "umlsterm",
"text": [
"cell"
],
"offsets": [
[
893,
897
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0007634"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s6-t7",
"type": "umlsterm",
"text": [
"carcinoma"
],
"offsets": [
[
898,
907
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0007097"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s6-t8",
"type": "umlsterm",
"text": [
"squamous cell carcinoma"
],
"offsets": [
[
884,
907
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0007137"
}
]
},
{
"id": "HNO.00480444.eng.abstr-s7-t1",
"type": "umlsterm",
"text": [
"micronucleus"
],
"offsets": [
[
997,
1009
]
],
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[] |
[] |
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] |
HNO.00480451.eng.abstr
|
HNO.00480451.eng.abstr
|
[
{
"id": "HNO.00480451.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In individual patients with head and neck squamous cell carcinomas ( HNSCC ) , established prognostic factors do not satisfactorily predict clinical outcome . For the first time we investigated a total of 100 HNSCC by Comparative Genomic Hybridization ( CGH ) to define chromosomal alterations that are associated with the patients prognosis . Patients were followed for at latest 4 but at least 2 years after surgery or until death . During this observation period twenty-nine of them died because of cancer disease . The Kaplan-Meier method was used plotting survival curves for every single chromosomal alteration as well as every clinico-pathological parameter . The curves were tested for significance by the log rank as well as the Breslow test . Significance of particular prognostic parameters was then evaluated by the Cox regression model . The overall survival time as well as the recurrence free survival time were significantly lower in patients who's tumors showed amplifications of the chromosomal region 11q13 ( p=0.0008 for LR and p=0.0024 for B ) . The survival time of the patients was also lower if the carcinomas carried overrepresentations of chromosome 3q ( p=0.0299 for LR and p=0.0546 for B ) . Multivariate analysis ( Cox's proportional hazards model ) revealed both alterations as most important independent prognostic factors in HNSCC . None of the conventional clinico-pathological parameters ( pT- , pN-status , UICC stage , grading ) achieved statistical significance in the multivariate model . These results suggest that in HNSCC the occurence of 11q13 amplification and 3q overrepresentation are highly significant independent prognostic markers and of better value than the established TNM and grading criteria ."
],
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[
0,
1747
]
]
}
] |
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}
] |
[] |
[] |
[
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HNO.00480462.eng.abstr
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HNO.00480462.eng.abstr
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"Auditory similarities in voices of monozygotic twins have already been described in the literature . However , is there a clinical relevance ? Thus , the present study was designed to identify parameters of vocal performance and acoustic features which are significantly more similar in monozygotic twins than in non-related persons . In our hypothesis , comparable prerequisites for an increased vocal load in a profession or in an artistic education of the voice could be due to these similarities . We compared intra-pair differences with data from a control group . Moreover , we examined the correlation of intra-pair differences with the age of the monozygotic twins . A greater difference in older twin pairs than in younger pairs could show the effect of an exogene influence . In addition to the few phoniatric studies in twins in the literature , we used current methods for acoustic analysis . We examined seven parameters of vocal performance and three acoustic features in 31 monozygotic twin pairs ( median age 36 years , range 18-75 years ) and compared them with 30 control group pairs , which consisted of non-related persons of the same age and sex , newly combined from the group of monozygotic twins ( \" statistical twins \" ) . We found significant differences in seven of ten parameters ( vocal range , highest and lowest vocal fundamental frequency , fundamental speaking frequency , maximum voice intensity , number of partials , vibrato of intensity ; U-test by Mann-Whitney ) . No correlation of the differences of the identical twins with age was found in the examined parameters . The voices of identical twins are significantly more similar than those of non-related persons regarding the above mentioned features . Thus , the suitability of the voices of monozygotic twins for professions with a high demand on voice is comparable . Results of the group comparison correlate largely with the literature . The missing correlation with age could be due to the fact that the environmental effects were not measurable , and/or the development of the voice is more influenced by genetic effects ."
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[] |
[] |
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] |
HNO.00480470.eng.abstr
|
HNO.00480470.eng.abstr
|
[
{
"id": "HNO.00480470.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Squamous cell carcinomas are rare malignant tumors of the major and minor salivary glands in the head region . This is the report of a squamous cell carcinoma within a cyst of the submandibular gland . Clinical , histological and immunohistochemical findings are presented , and the importance as well as the therapeutic strategy of this very rare malignant tumor of the salivary glands are discussed ."
],
"offsets": [
[
0,
402
]
]
}
] |
[
{
"id": "HNO.00480470.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"cell"
],
"offsets": [
[
9,
13
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0007634"
}
]
},
{
"id": "HNO.00480470.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"carcinomas"
],
"offsets": [
[
14,
24
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0007097"
}
]
},
{
"id": "HNO.00480470.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"malignant"
],
"offsets": [
[
34,
43
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0006826"
}
]
},
{
"id": "HNO.00480470.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"tumors"
],
"offsets": [
[
44,
50
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0027651"
}
]
},
{
"id": "HNO.00480470.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"minor"
],
"offsets": [
[
68,
73
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0026193"
}
]
},
{
"id": "HNO.00480470.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"head"
],
"offsets": [
[
97,
101
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0018670"
}
]
},
{
"id": "HNO.00480470.eng.abstr-s1-t7",
"type": "umlsterm",
"text": [
"malignant tumors"
],
"offsets": [
[
34,
50
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0006826"
}
]
},
{
"id": "HNO.00480470.eng.abstr-s1-t8",
"type": "umlsterm",
"text": [
"salivary glands"
],
"offsets": [
[
74,
89
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0036098"
}
]
},
{
"id": "HNO.00480470.eng.abstr-s1-t9",
"type": "umlsterm",
"text": [
"head region"
],
"offsets": [
[
97,
108
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0018670"
}
]
},
{
"id": "HNO.00480470.eng.abstr-s1-t10",
"type": "umlsterm",
"text": [
"Squamous cell carcinomas"
],
"offsets": [
[
0,
24
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0007137"
}
]
},
{
"id": "HNO.00480470.eng.abstr-s1-t11",
"type": "umlsterm",
"text": [
"minor salivary glands"
],
"offsets": [
[
68,
89
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0036099"
}
]
},
{
"id": "HNO.00480470.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"cell"
],
"offsets": [
[
144,
148
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0007634"
}
]
},
{
"id": "HNO.00480470.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"carcinoma"
],
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[
149,
158
]
],
"normalized": [
{
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"db_id": "C0007097"
}
]
},
{
"id": "HNO.00480470.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"cyst"
],
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[
168,
172
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0010709"
}
]
},
{
"id": "HNO.00480470.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"submandibular gland"
],
"offsets": [
[
180,
199
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0038556"
}
]
},
{
"id": "HNO.00480470.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"squamous cell carcinoma"
],
"offsets": [
[
135,
158
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0007137"
}
]
},
{
"id": "HNO.00480470.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"findings"
],
"offsets": [
[
250,
258
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0243095"
}
]
},
{
"id": "HNO.00480470.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"therapeutic"
],
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309,
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]
],
"normalized": [
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"db_id": "C0039796"
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]
},
{
"id": "HNO.00480470.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"malignant"
],
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348,
357
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],
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},
{
"id": "HNO.00480470.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"tumor"
],
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[
358,
363
]
],
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},
{
"id": "HNO.00480470.eng.abstr-s3-t5",
"type": "umlsterm",
"text": [
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],
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348,
363
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],
"normalized": [
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]
},
{
"id": "HNO.00480470.eng.abstr-s3-t6",
"type": "umlsterm",
"text": [
"salivary glands"
],
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[
371,
386
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0036098"
}
]
}
] |
[] |
[] |
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},
{
"id": "HNO.00480470.eng.abstr-s2-r4-t1.1-t2.1",
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},
{
"id": "HNO.00480470.eng.abstr-s2-r5-t4.1-t5.1",
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},
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"id": "HNO.00480470.eng.abstr-s2-r6-t4.1-t3.1",
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},
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{
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{
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},
{
"id": "HNO.00480470.eng.abstr-s3-r3-t5.1-t1.1",
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},
{
"id": "HNO.00480470.eng.abstr-s3-r4-t1.1-t3.1",
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"arg2_id": "HNO.00480470.eng.abstr-s3-t3",
"normalized": []
}
] |
HNO.00480489.eng.abstr
|
HNO.00480489.eng.abstr
|
[
{
"id": "HNO.00480489.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Nitric oxide ( NO ) can play an important role in the regulation of vascular tone and neurotransmission , as well as in non-specific immunoreactions and inflammation in a variety of tissues . Increased quantities of nitric oxide in respired air can be measured during inflammatory processes . However , the exact role and precise sources of NO under physiological and pathophysiological conditions within the airways remain to be defined ."
],
"offsets": [
[
0,
439
]
]
}
] |
[
{
"id": "HNO.00480489.eng.abstr-s1-t1",
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"text": [
"oxide"
],
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[
7,
12
]
],
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{
"db_name": "UMLS",
"db_id": "C0030015"
}
]
},
{
"id": "HNO.00480489.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"role"
],
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42,
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]
],
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"db_id": "C0035820"
}
]
},
{
"id": "HNO.00480489.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"regulation"
],
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[
54,
64
]
],
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{
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"db_id": "C0034982"
},
{
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}
]
},
{
"id": "HNO.00480489.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"inflammation"
],
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[
153,
165
]
],
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"db_id": "C0021368"
}
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},
{
"id": "HNO.00480489.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"tissues"
],
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[
182,
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]
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"db_id": "C0040300"
}
]
},
{
"id": "HNO.00480489.eng.abstr-s1-t6",
"type": "umlsterm",
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"Nitric oxide"
],
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[
0,
12
]
],
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"db_id": "C0028128"
}
]
},
{
"id": "HNO.00480489.eng.abstr-s2-t1",
"type": "umlsterm",
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"oxide"
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[
223,
228
]
],
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}
]
},
{
"id": "HNO.00480489.eng.abstr-s2-t2",
"type": "umlsterm",
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"air"
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241,
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]
],
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}
]
},
{
"id": "HNO.00480489.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"nitric oxide"
],
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216,
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]
],
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"db_id": "C0028128"
}
]
},
{
"id": "HNO.00480489.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"exact"
],
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[
307,
312
]
],
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{
"db_name": "UMLS",
"db_id": "C0059927"
}
]
},
{
"id": "HNO.00480489.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"role"
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313,
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]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0035820"
}
]
}
] |
[] |
[] |
[
{
"id": "HNO.00480489.eng.abstr-s1-r1-t5.1-t6.1",
"type": "produces",
"arg1_id": "HNO.00480489.eng.abstr-s1-t5",
"arg2_id": "HNO.00480489.eng.abstr-s1-t6",
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},
{
"id": "HNO.00480489.eng.abstr-s1-r2-t1.1-t6.1",
"type": "interacts_with",
"arg1_id": "HNO.00480489.eng.abstr-s3-t1",
"arg2_id": "HNO.00480489.eng.abstr-s1-t6",
"normalized": []
},
{
"id": "HNO.00480489.eng.abstr-s1-r3-t6.1-t3.1",
"type": "affects",
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"arg2_id": "HNO.00480489.eng.abstr-s2-t3",
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},
{
"id": "HNO.00480489.eng.abstr-s1-r4-t3.1-t2.1",
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"arg2_id": "HNO.00480489.eng.abstr-s3-t2",
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},
{
"id": "HNO.00480489.eng.abstr-s1-r5-t6.1-t1.1",
"type": "interacts_with",
"arg1_id": "HNO.00480489.eng.abstr-s1-t6",
"arg2_id": "HNO.00480489.eng.abstr-s3-t1",
"normalized": []
},
{
"id": "HNO.00480489.eng.abstr-s1-r6-t1.1-t3.1",
"type": "affects",
"arg1_id": "HNO.00480489.eng.abstr-s3-t1",
"arg2_id": "HNO.00480489.eng.abstr-s2-t3",
"normalized": []
},
{
"id": "HNO.00480489.eng.abstr-s1-r7-t3.1-t6.1",
"type": "produces",
"arg1_id": "HNO.00480489.eng.abstr-s2-t3",
"arg2_id": "HNO.00480489.eng.abstr-s1-t6",
"normalized": []
},
{
"id": "HNO.00480489.eng.abstr-s1-r8-t6.1-t5.1",
"type": "disrupts",
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"arg2_id": "HNO.00480489.eng.abstr-s1-t5",
"normalized": []
},
{
"id": "HNO.00480489.eng.abstr-s1-r9-t3.1-t3.2",
"type": "isa",
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"arg2_id": "HNO.00480489.eng.abstr-s1-t3",
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},
{
"id": "HNO.00480489.eng.abstr-s1-r10-t5.1-t3.1",
"type": "location_of",
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"arg2_id": "HNO.00480489.eng.abstr-s2-t3",
"normalized": []
},
{
"id": "HNO.00480489.eng.abstr-s2-r1-t3.1-t1.1",
"type": "interacts_with",
"arg1_id": "HNO.00480489.eng.abstr-s2-t3",
"arg2_id": "HNO.00480489.eng.abstr-s3-t1",
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},
{
"id": "HNO.00480489.eng.abstr-s2-r2-t3.1-t2.1",
"type": "isa",
"arg1_id": "HNO.00480489.eng.abstr-s2-t3",
"arg2_id": "HNO.00480489.eng.abstr-s3-t2",
"normalized": []
},
{
"id": "HNO.00480489.eng.abstr-s2-r3-t1.1-t2.1",
"type": "isa",
"arg1_id": "HNO.00480489.eng.abstr-s3-t1",
"arg2_id": "HNO.00480489.eng.abstr-s3-t2",
"normalized": []
},
{
"id": "HNO.00480489.eng.abstr-s2-r4-t1.1-t3.1",
"type": "interacts_with",
"arg1_id": "HNO.00480489.eng.abstr-s3-t1",
"arg2_id": "HNO.00480489.eng.abstr-s2-t3",
"normalized": []
}
] |
HNO.00480496.eng.abstr
|
HNO.00480496.eng.abstr
|
[
{
"id": "HNO.00480496.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Beta-trace protein is a lipocalin that was recently identified as prostaglandin D synthase and represents a major constituent of human cerebrospinal fluid . Beta-trace protein , similar to 2-transferrin , has been used as an immunological marker for the detection of cerebrospinal fluid . Between 1982 and 1999 , 130 specimens from 101 patients with suspected cerebrospinal fluid leaks of the anterior or lateral skull base have been investigated for beta-trace protein . The specimens were analyzed by one-dimensional immunoelectrophoresis using Laurrell's electroimmunoassay . In all , beta-trace protein could be detected in 57 specimens and was absent in 73. All case notes were studied retrospectively . In correlation with the clinical course and the findings of CT of the paranasal sinuses , high resolution CT of the petrous bones , CT cisternography , NMR , 111In-DTPA radionuclide cisternography , intraoperative findings , visualization of sodium-fluorescein stained cerebrospinal fluid using endoscopic blue light or testing for glucose , there was no false-positive result . A false-negative result occurred in two cases . These findings show that the beta-trace test has a sensitivity of 97.3% and a specificity of nearly 100% . Our findings show that analysis of beta-trace protein can be a valuable test for detecting CSF leakage and has certain advantages in comparison with the 2-transferrin assay ."
],
"offsets": [
[
0,
1417
]
]
}
] |
[
{
"id": "HNO.00480496.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"Beta-trace"
],
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[
0,
10
]
],
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{
"db_name": "UMLS",
"db_id": "C0053396"
},
{
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"db_id": "C0220914"
},
{
"db_name": "UMLS",
"db_id": "C0040665"
},
{
"db_name": "UMLS",
"db_id": "C0005270"
},
{
"db_name": "UMLS",
"db_id": "C0005223"
},
{
"db_name": "UMLS",
"db_id": "C0005157"
},
{
"db_name": "UMLS",
"db_id": "C0053360"
},
{
"db_name": "UMLS",
"db_id": "C0017954"
}
]
},
{
"id": "HNO.00480496.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"protein"
],
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[
11,
18
]
],
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{
"db_name": "UMLS",
"db_id": "C0033684"
}
]
},
{
"id": "HNO.00480496.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"prostaglandin"
],
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[
66,
79
]
],
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{
"db_name": "UMLS",
"db_id": "C0033554"
}
]
},
{
"id": "HNO.00480496.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"human"
],
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[
129,
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]
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"db_id": "C0020114"
}
]
},
{
"id": "HNO.00480496.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"prostaglandin D"
],
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[
66,
81
]
],
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"db_name": "UMLS",
"db_id": "C0033558"
}
]
},
{
"id": "HNO.00480496.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"cerebrospinal fluid"
],
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[
135,
154
]
],
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{
"db_name": "UMLS",
"db_id": "C0007807"
},
{
"db_name": "UMLS",
"db_id": "C0007806"
}
]
},
{
"id": "HNO.00480496.eng.abstr-s1-t7",
"type": "umlsterm",
"text": [
"prostaglandin D synthase"
],
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[
66,
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]
],
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"db_name": "UMLS",
"db_id": "C0072296"
}
]
},
{
"id": "HNO.00480496.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"Beta-trace"
],
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157,
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]
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"db_id": "C0053396"
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"db_name": "UMLS",
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"db_id": "C0005223"
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"db_name": "UMLS",
"db_id": "C0005157"
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"db_id": "C0053360"
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{
"db_name": "UMLS",
"db_id": "C0017954"
}
]
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{
"id": "HNO.00480496.eng.abstr-s2-t2",
"type": "umlsterm",
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"protein"
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},
{
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"type": "umlsterm",
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"marker"
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{
"id": "HNO.00480496.eng.abstr-s2-t4",
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"cerebrospinal fluid"
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}
]
},
{
"id": "HNO.00480496.eng.abstr-s3-t1",
"type": "umlsterm",
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"patients"
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]
},
{
"id": "HNO.00480496.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"anterior"
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}
]
},
{
"id": "HNO.00480496.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"skull"
],
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]
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]
},
{
"id": "HNO.00480496.eng.abstr-s3-t4",
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"db_name": "UMLS",
"db_id": "C0053360"
},
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"db_name": "UMLS",
"db_id": "C0017954"
}
]
},
{
"id": "HNO.00480496.eng.abstr-s3-t5",
"type": "umlsterm",
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"protein"
],
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[
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]
],
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"db_id": "C0033684"
}
]
},
{
"id": "HNO.00480496.eng.abstr-s3-t6",
"type": "umlsterm",
"text": [
"cerebrospinal fluid"
],
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[
360,
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]
],
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}
]
},
{
"id": "HNO.00480496.eng.abstr-s3-t7",
"type": "umlsterm",
"text": [
"skull base"
],
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[
413,
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]
],
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{
"db_name": "UMLS",
"db_id": "C0149543"
}
]
},
{
"id": "HNO.00480496.eng.abstr-s3-t8",
"type": "umlsterm",
"text": [
"beta-trace protein"
],
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[
451,
469
]
],
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{
"db_name": "UMLS",
"db_id": "C0005171"
}
]
},
{
"id": "HNO.00480496.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"immunoelectrophoresis"
],
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[
519,
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],
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"db_name": "UMLS",
"db_id": "C0020997"
}
]
},
{
"id": "HNO.00480496.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"beta-trace"
],
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[
588,
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]
],
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{
"db_name": "UMLS",
"db_id": "C0053396"
},
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"db_name": "UMLS",
"db_id": "C0220914"
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{
"db_name": "UMLS",
"db_id": "C0040665"
},
{
"db_name": "UMLS",
"db_id": "C0005270"
},
{
"db_name": "UMLS",
"db_id": "C0005223"
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{
"db_name": "UMLS",
"db_id": "C0005157"
},
{
"db_name": "UMLS",
"db_id": "C0053360"
},
{
"db_name": "UMLS",
"db_id": "C0017954"
}
]
},
{
"id": "HNO.00480496.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"protein"
],
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[
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]
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{
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"db_id": "C0033684"
}
]
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] |
[] |
[] |
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HNO.00480508.eng.abstr
|
HNO.00480508.eng.abstr
|
[
{
"id": "HNO.00480508.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The growing popularity of prosthetic voice restoration after total laryngectomy confronts ENT specialists with an increasing number of prosthesis-related complications . The ENT specialist should be familiar with the management of these complications in order to maintain the patients speech and social rehabilitation . In a retrospective study on 108 consecutive patients , complications were encountered in 30% . The incidence was not related to the factors age or primary vs. secondary insertion of the prosthesis . Complications consisted of formation of granulation tissue ( 15,7% ) , shunt dilatation ( 5,5% ) , loss of prosthesis ( 3,7% ) , local cellulitis ( 2,8% ) , extrusion ( 1,9% ) , ingrowth of prosthesis ( 1,9% ) and formation of excessive scar tissue with dislocation of prosthesis ( 0,9% ) . Permanent removal of the prosthesis due to complications was necessary in 3 cases ( 2,8% ) . Therapeutic measures for the management of complications are described and evaluated . The treatment of complications was well tolerated by all patients and led to satisfying results in most cases . Our observations show that prosthetic voice rehabilitation is associated with various difficulties and complications , but that these can be handled quite easily and successfully in the majority of cases ."
],
"offsets": [
[
0,
1307
]
]
}
] |
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] |
[] |
[] |
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HNO.00480517.eng.abstr
|
HNO.00480517.eng.abstr
|
[
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"type": "abstract",
"text": [
"Reconstruction of lip defects presents a challenge to the surgeon . Apart from attaining a good aesthetic result , preserving the function of the oral sphincter is an essential objective . A variety of techniques and modifications of procedures for reconstructing lip defects have been reported in the literature . It is up to the surgeon to select the reconstruction procedure ensuring optimum functional and cosmetic results , depending on the location , size , and depth of the defect . The division of the lips into aesthetic subunits can prove very beneficial in designing lip reconstruction procedures . The upper lip is divided into three aesthetic subunits : two lateral subunits and a median subunit , the philtrum . The lower lip constitutes a single subunit . In this study , established reconstruction techniques are discussed and a concept serving to facilitate the appropriate choice of technique is introduced . This concept differentiates between vermilion defects on the one hand , and partial-thickness and full-thickness lip defects on the other hand . For the lower lip , the full-thickness defects are classified as defects involving one-third , one-third to two-thirds of the lower lip width , and between two-thirds and complete loss of lip tissue . For the upper lip , a distinction is made between isolated defects of the central and lateral subunits and combined defects of the central and lateral subunits . Important principles of surgery and the advantages or disadvantages of different reconstruction techniques are discussed ."
],
"offsets": [
[
0,
1557
]
]
}
] |
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[] |
[] |
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] |
HNO.00480527.eng.abstr
|
HNO.00480527.eng.abstr
|
[
{
"id": "HNO.00480527.eng.abstr-passage-0",
"type": "abstract",
"text": [
"We treated 64 patients with the diagnosis of laryngitis gastrica with Antra ( Omeprazol ) in doses of 10 , 20 , and 40 mg . To determine the success of the therapy , pH monitoring of the esophagus and hypopharynx , the voice status and measurement of vocal penetrating capacity were used . The results prove that a 20-mg dose of Antra is suitable for the therapy of laryngitis gastrica with a high rate of success . Problems which arose during the investigation , consequent changes of the original concept of the project as well as new aspects and questions which resulted from this are discussed with respect to further investigation ."
],
"offsets": [
[
0,
637
]
]
}
] |
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[] |
[] |
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HNO.00480533.eng.abstr
|
HNO.00480533.eng.abstr
|
[
{
"id": "HNO.00480533.eng.abstr-passage-0",
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],
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[
0,
526
]
]
}
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}
] |
[] |
[] |
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HNO.00480562.eng.abstr
|
HNO.00480562.eng.abstr
|
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{
"id": "HNO.00480562.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Looking back at 150 years of the development of septorhinoplasty - 50 of which I have experienced myself - one can conclude that recent developments go back to the nineteenth century . In the era of \" minimal invasive surgery \" the \" open approach \" to septorhinoplasty should no longer be indicated . The sublabial approach in the sense of minimal invasive surgery is recommended ."
],
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0,
382
]
]
}
] |
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[] |
[] |
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HNO.00480573.eng.abstr
|
HNO.00480573.eng.abstr
|
[
{
"id": "HNO.00480573.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Antiphlogistic-rheologic infusion therapy is a widespread and well-established treatment modality for acute idiopathic facial paralysis ( AIFP ) in many German centers of otorhinolaryngology . However , there is still a lack of convincing data concerning this regimen's functional results and side effects . The medical records of 344 patients who were treated for AIFP between 1987 and 1997 were analyzed retrospectively . In 239 cases there was reliable information on functional outcome . Therapy consisted uniformly of intravenous infusion with prednisolone ( 250 mg initially , then tapering over 18 days ) and simultaneous administration of dextran and pentoxifylline . From 239 patients with non-recurrent palsy having received treatment within 12 days after onset , 92 . 1% recovered completely without sequelae . In case of incomplete palsy ( House-Brackmann grade II-V ) , normal facial function was restored in 97,7% of cases . Results were significantly better in the group in which therapy had been started within 3 days after onset of palsy . Adverse effects occurred rarely and were transient and mild in most cases . High-dose prednisolone in combination with low-molecular dextran and pentoxifylline for AIFP is a safe treatment modality leading to recovery rates superior to the most optimistic observations of the natural course of Bell's palsy . In the absence of a definitive controlled trial , the present study , although retrospective , is considered valid to show the effectiveness of our protocol . In the light of our data and of other publications , early treatment with corticosteroids in sufficient dosage seems appropriate , while therapeutic nihilism in AIFP does not seem justified ."
],
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{
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HNO.00480583.eng.abstr
|
HNO.00480583.eng.abstr
|
[
{
"id": "HNO.00480583.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Fine needle aspiration biopsy ( FNAB ) under ultrasound control is an established diagnostic procedure for the head and neck region . Because of the disintegration of tissues , the diagnostic value of the method is limited resulting in only moderate specificity . In a prospective study , we performed a new , semi-automatic biopsy method in patients who had been diagnosed with sonographically confirmed pathologic masses in the head-neck region . This biopsy is carried out with a spring-loaded biopsy pistol which uses a disposable 20-gauge , specially designed cutting needle . Because this method combines the low invasiveness of FNAB with the high specificity of an excisional biopsy , a high tissue quality is obtained . Comparing these bioptic results with those of subsequent excisional biopsies proves that this new method yields a sensitivity of close to 100% for the detection of lymph node metastases of squamous cell carcinomas ( SCC ) . The tissue cylinders have a reproducible size and allow ultrastructural investigations in the transmission electron microscope ( TEM ) on the ultrastructural level . Due to the excellent tissue preservation in the biopsy cylinders , ultrastructural studies , using transmission electron microscopy , may be carried out with the biopsy material . Furthermore , following paraffin embedding of biopsy cylinders , serial sections may be obtained for special staining techniques , and immunohistological investigations are possible which may serve as an adjunct in the diagnosis of , e.g. , lymphoproliferative lesions with a sensitivity of 96% . Summarizing , the new semi-automatic biopsy technique obtains tissue probes of high quality with low invasiveness which enables highly sensitive diagnosis of head and neck lesions ."
],
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{
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}
] |
HNO.00480589.eng.abstr
|
HNO.00480589.eng.abstr
|
[
{
"id": "HNO.00480589.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A metaanalysis on pharmacological and psychological treatment reports was conducted in order to evaluate the overall effectiveness of these treatment conditions in chronic tinnitus . A totality of 109 treatment studies published between 1976 and 3/1995 and meeting minimal inclusion criteria was located , but only 24 studies reporting sufficient information could be analyzed . The methodological quality of the studies was evaluated by a coding scheme , and the resulting index of effectiveness has been weighted by this standard as well as by sample size . Effect sizes of pharmacological studies were ES=1.27 and by this higher than the ones for psychological studies with ES=0.88. This finding is attenuated by high ( unspecific ) placebo effects of ES=0.65 in pharmacological studies compared to ES=0.10 in psychological studies . In general , patients from psychological studies further improve after treatment in cases where catamnestic measurements have been conducted ."
],
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[
0,
979
]
]
}
] |
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{
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14
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{
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]
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109,
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]
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{
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]
},
{
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]
},
{
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]
},
{
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]
},
{
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736,
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]
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{
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]
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{
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]
},
{
"id": "HNO.00480589.eng.abstr-s5-t4",
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902,
917
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],
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{
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]
}
] |
[] |
[] |
[
{
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{
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},
{
"id": "HNO.00480589.eng.abstr-s5-r1-t3.1-t2.1",
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{
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},
{
"id": "HNO.00480589.eng.abstr-s5-r5-t2.1-t1.1",
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},
{
"id": "HNO.00480589.eng.abstr-s5-r6-t3.1-t2.1",
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"arg2_id": "HNO.00480589.eng.abstr-s5-t2",
"normalized": []
}
] |
HNO.00480606.eng.abstr
|
HNO.00480606.eng.abstr
|
[
{
"id": "HNO.00480606.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Maternal anxiety in the event of a false positive result is an argument against universal hearing screening in newborns . The aim of this study was to investigate the mothers ' attitudes towards neonatal hearing screening and their anxiety in case of a positive result ."
],
"offsets": [
[
0,
270
]
]
}
] |
[
{
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[
9,
16
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}
]
},
{
"id": "HNO.00480606.eng.abstr-s1-t2",
"type": "umlsterm",
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"universal"
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80,
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]
],
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}
]
},
{
"id": "HNO.00480606.eng.abstr-s1-t3",
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"hearing"
],
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90,
97
]
],
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}
]
},
{
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98,
107
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}
]
},
{
"id": "HNO.00480606.eng.abstr-s1-t5",
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111,
119
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"aim"
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126,
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}
]
},
{
"id": "HNO.00480606.eng.abstr-s2-t2",
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],
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167,
174
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{
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}
]
}
] |
[] |
[] |
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{
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{
"id": "HNO.00480606.eng.abstr-s2-r6-t5.1-t4.1",
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HNO.00480613.eng.abstr
|
HNO.00480613.eng.abstr
|
[
{
"id": "HNO.00480613.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Sarcoidosis , a systemic granulomatous disease of unknown cause , may involve any body organ . The most common manifestation in the head-neck area is lymphnode sarcoidosis or , alternatively , Heerfordt's syndrome ( with involvement of lacrimal and parotid gland and possible facial palsy ) . Far less common is a isolated laryngeal sarcoidosis . The typical histopathological appearance proves the diagnosis . However , obtaining representative and sufficent biopsy material in some cases may carry risks for the patients or might technically be difficult . In these cases , the clinician can fall back on two other , noninvasive diagnostic procedures : ACE level activity determination in blood serum and 67gallium citrate scintigraphy . Elevated ACE levels in combination with a positive 67gallium scintigraphy have a specificity ( combined ) of 99% . As a valuable side effect , this procedure sensitively may discover additional disease in the body and also serves well as a therapy-control examination . The presented case report shows clearly that these clinical methods , if combined , are sufficient for diagnosis of Heerfordt's syndrome/sarcoidosis ; no additional histopathological examination is required ."
],
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[] |
[] |
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HNO.00480616.eng.abstr
|
HNO.00480616.eng.abstr
|
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[] |
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HNO.00480639.eng.abstr
|
HNO.00480639.eng.abstr
|
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{
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]
}
] |
[] |
[] |
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] |
HNO.00480645.eng.abstr
|
HNO.00480645.eng.abstr
|
[
{
"id": "HNO.00480645.eng.abstr-passage-0",
"type": "abstract",
"text": [
"There is undoubtedly a need for a safe disinfection method of optical instruments used by ENT specialists . So far , a standard method that sufficiently covers the risk of infection for patients and medical staff alike while serving the need of practicability in daily routine has not been established . Therefore , in the ENT departments of the hospitals of Mannheim , Kaiserslautern , and Tuebingen , studies on the disinfection of rigid optical instruments without working channel were performed between February 1999 and May 1999. Instruments were wiped either with an aldehyde or alcohol ( ethanol 80% ) and germs were detected by quantitative swab cultures . As discussed in the article , disinfection with ethanol proved to be at least equally efficient if not better than disinfection with aldehyde . Therefore , it fully serves the requirements of a safe method for disinfection optical instruments without working channels ."
],
"offsets": [
[
0,
934
]
]
}
] |
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{
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{
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] |
[] |
[] |
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}
] |
HNO.00480650.eng.abstr
|
HNO.00480650.eng.abstr
|
[
{
"id": "HNO.00480650.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Background and objective . The high prevalence of aspirin intolerance in asthmatics and patients with nasal polyps as well as reports of familial clustering suggest a genetic disposition of this disease . Our study aimed at obtaining further evidence of hereditary factors in this disease . We included 33 unselected patients from 28 families with aspirin intolerance and rhinosinusitis in this study . Controls were recruited from individuals treated in our ENT clinic for diseases other than aspirin intolerance ( n=52)."
],
"offsets": [
[
0,
522
]
]
}
] |
[
{
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"objective"
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15,
24
]
],
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"db_id": "C0018017"
}
]
},
{
"id": "HNO.00480650.eng.abstr-s2-t1",
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"text": [
"prevalence"
],
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[
36,
46
]
],
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]
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{
"id": "HNO.00480650.eng.abstr-s2-t2",
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"aspirin"
],
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50,
57
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{
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"asthmatics"
],
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73,
83
]
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{
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"patients"
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88,
96
]
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]
},
{
"id": "HNO.00480650.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"polyps"
],
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[
108,
114
]
],
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{
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{
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{
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102,
114
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{
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281,
288
]
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{
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]
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{
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317,
325
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{
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342
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355
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},
{
"id": "HNO.00480650.eng.abstr-s5-t2",
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},
{
"id": "HNO.00480650.eng.abstr-s5-t3",
"type": "umlsterm",
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501
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],
"normalized": [
{
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}
]
}
] |
[] |
[] |
[
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"id": "HNO.00480650.eng.abstr-s2-r6-t7.1-t4.1",
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},
{
"id": "HNO.00480650.eng.abstr-s2-r7-t3.1-t5.1",
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},
{
"id": "HNO.00480650.eng.abstr-s2-r8-t2.1-t3.1",
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},
{
"id": "HNO.00480650.eng.abstr-s2-r9-t8.1-t4.1",
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},
{
"id": "HNO.00480650.eng.abstr-s2-r10-t2.1-t3.1",
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"id": "HNO.00480650.eng.abstr-s2-r14-t8.1-t3.1",
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"id": "HNO.00480650.eng.abstr-s2-r15-t3.1-t4.1",
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},
{
"id": "HNO.00480650.eng.abstr-s2-r17-t2.1-t8.1",
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"id": "HNO.00480650.eng.abstr-s2-r18-t7.1-t5.1",
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},
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"id": "HNO.00480650.eng.abstr-s2-r20-t5.1-t4.1",
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},
{
"id": "HNO.00480650.eng.abstr-s5-r1-t3.1-t1.1",
"type": "affects",
"arg1_id": "HNO.00480650.eng.abstr-s5-t3",
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},
{
"id": "HNO.00480650.eng.abstr-s5-r2-t3.1-t1.1",
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"arg2_id": "HNO.00480650.eng.abstr-s5-t1",
"normalized": []
}
] |
HNO.00480665.eng.abstr
|
HNO.00480665.eng.abstr
|
[
{
"id": "HNO.00480665.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Orbital pseudotumor is a nonspecific inflammatory process of unknown etiology that can be divided histopathologically into three basic types : granulomatous , lymphoid , and sclerosing . Between 1995 and 1998 , 12 patients with pseudotumor orbitae were treated in the ENT Department of the University of Saarland . Histopathological examination showed granulomatous type of pseudotumor in six , lymphoid in three , and sclerosing in three patients . In seven cases the pseudotumor orbitae were medially located and in four cases laterally . In one patient nearly all orbital structures were infiltrated ."
],
"offsets": [
[
0,
604
]
]
}
] |
[
{
"id": "HNO.00480665.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"etiology"
],
"offsets": [
[
69,
77
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0015127"
},
{
"db_name": "UMLS",
"db_id": "C0007463"
}
]
},
{
"id": "HNO.00480665.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"patients"
],
"offsets": [
[
214,
222
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "HNO.00480665.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"University"
],
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[
290,
300
]
],
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{
"db_name": "UMLS",
"db_id": "C0041740"
}
]
},
{
"id": "HNO.00480665.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"Histopathological"
],
"offsets": [
[
315,
332
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0243140"
}
]
},
{
"id": "HNO.00480665.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"patients"
],
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[
439,
447
]
],
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{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "HNO.00480665.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"patient"
],
"offsets": [
[
548,
555
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
}
] |
[] |
[] |
[
{
"id": "HNO.00480665.eng.abstr-s2-r1-t1.1-t2.1",
"type": "uses",
"arg1_id": "HNO.00480665.eng.abstr-s5-t1",
"arg2_id": "HNO.00480665.eng.abstr-s3-t2",
"normalized": []
}
] |
HNO.00480671.eng.abstr
|
HNO.00480671.eng.abstr
|
[
{
"id": "HNO.00480671.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Non-syndromic neurosensory recessive deafness ( NSRD ) is one of the most common human sensory disorders . Mutations in the connexin 26 gene have been established as a major cause of inherited and sporadic non-syndromic deafness in different populations ."
],
"offsets": [
[
0,
255
]
]
}
] |
[
{
"id": "HNO.00480671.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"deafness"
],
"offsets": [
[
37,
45
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0011053"
},
{
"db_name": "UMLS",
"db_id": "C0018772"
}
]
},
{
"id": "HNO.00480671.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"human"
],
"offsets": [
[
81,
86
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0020114"
}
]
},
{
"id": "HNO.00480671.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"disorders"
],
"offsets": [
[
95,
104
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0012634"
}
]
},
{
"id": "HNO.00480671.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"sensory disorders"
],
"offsets": [
[
87,
104
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0152027"
}
]
},
{
"id": "HNO.00480671.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"Mutations"
],
"offsets": [
[
107,
116
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0026882"
}
]
},
{
"id": "HNO.00480671.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"connexin"
],
"offsets": [
[
124,
132
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0110611"
}
]
},
{
"id": "HNO.00480671.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"gene"
],
"offsets": [
[
136,
140
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0017337"
}
]
},
{
"id": "HNO.00480671.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"cause"
],
"offsets": [
[
174,
179
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0015127"
}
]
},
{
"id": "HNO.00480671.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"deafness"
],
"offsets": [
[
220,
228
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0011053"
},
{
"db_name": "UMLS",
"db_id": "C0018772"
}
]
},
{
"id": "HNO.00480671.eng.abstr-s2-t6",
"type": "umlsterm",
"text": [
"populations"
],
"offsets": [
[
242,
253
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0032659"
}
]
}
] |
[] |
[] |
[
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},
{
"id": "HNO.00480671.eng.abstr-s1-r3-t1.1-t4.1",
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{
"id": "HNO.00480671.eng.abstr-s1-r4-t1.2-t4.1",
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"id": "HNO.00480671.eng.abstr-s1-r5-t1.1-t1.2",
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"id": "HNO.00480671.eng.abstr-s1-r6-t1.1-t2.1",
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"id": "HNO.00480671.eng.abstr-s2-r2-t2.1-t1.1",
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"id": "HNO.00480671.eng.abstr-s2-r5-t2.1-t5.2",
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"id": "HNO.00480671.eng.abstr-s2-r6-t4.1-t1.1",
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{
"id": "HNO.00480671.eng.abstr-s2-r7-t2.1-t1.1",
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"id": "HNO.00480671.eng.abstr-s2-r8-t5.2-t4.1",
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},
{
"id": "HNO.00480671.eng.abstr-s2-r9-t4.1-t2.1",
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{
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},
{
"id": "HNO.00480671.eng.abstr-s2-r11-t5.2-t1.1",
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},
{
"id": "HNO.00480671.eng.abstr-s2-r12-t4.1-t1.1",
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{
"id": "HNO.00480671.eng.abstr-s2-r14-t1.1-t4.1",
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},
{
"id": "HNO.00480671.eng.abstr-s2-r15-t2.1-t1.1",
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},
{
"id": "HNO.00480671.eng.abstr-s2-r16-t3.1-t1.1",
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"id": "HNO.00480671.eng.abstr-s2-r17-t4.1-t1.1",
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{
"id": "HNO.00480671.eng.abstr-s2-r18-t1.1-t4.1",
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},
{
"id": "HNO.00480671.eng.abstr-s2-r19-t1.1-t2.1",
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},
{
"id": "HNO.00480671.eng.abstr-s2-r20-t6.1-t1.1",
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},
{
"id": "HNO.00480671.eng.abstr-s2-r21-t1.1-t5.2",
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},
{
"id": "HNO.00480671.eng.abstr-s2-r22-t5.2-t1.1",
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},
{
"id": "HNO.00480671.eng.abstr-s2-r23-t3.1-t1.1",
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{
"id": "HNO.00480671.eng.abstr-s2-r24-t3.1-t2.1",
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{
"id": "HNO.00480671.eng.abstr-s2-r25-t3.1-t5.2",
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},
{
"id": "HNO.00480671.eng.abstr-s2-r26-t1.1-t5.2",
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"normalized": []
},
{
"id": "HNO.00480671.eng.abstr-s2-r27-t5.2-t1.1",
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{
"id": "HNO.00480671.eng.abstr-s2-r28-t4.1-t5.2",
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{
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},
{
"id": "HNO.00480671.eng.abstr-s2-r30-t1.1-t4.1",
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{
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}
] |
HNO.00480684.eng.abstr
|
HNO.00480684.eng.abstr
|
[
{
"id": "HNO.00480684.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Angiosarcomas are very rare but highly malignant soft tissue tumors derived from the vascular endothelium . The tumor is most commonly found in the skin . The cancer is known to cause early and widespread metastases leading to a very poor prognosis of less than 24 months . The therapy of choice is radical surgery followed by adjuvant radiation ."
],
"offsets": [
[
0,
347
]
]
}
] |
[
{
"id": "HNO.00480684.eng.abstr-s1-t1",
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"Angiosarcomas"
],
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[
0,
13
]
],
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"db_id": "C0018923"
}
]
},
{
"id": "HNO.00480684.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"malignant"
],
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[
39,
48
]
],
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}
]
},
{
"id": "HNO.00480684.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"tissue"
],
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[
54,
60
]
],
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{
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"db_id": "C0040300"
}
]
},
{
"id": "HNO.00480684.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"tumors"
],
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[
61,
67
]
],
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{
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"db_id": "C0027651"
}
]
},
{
"id": "HNO.00480684.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"endothelium"
],
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[
94,
105
]
],
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{
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}
]
},
{
"id": "HNO.00480684.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"vascular endothelium"
],
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[
85,
105
]
],
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{
"db_name": "UMLS",
"db_id": "C0014261"
}
]
},
{
"id": "HNO.00480684.eng.abstr-s1-t7",
"type": "umlsterm",
"text": [
"soft tissue tumors"
],
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[
49,
67
]
],
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{
"db_name": "UMLS",
"db_id": "C0037579"
}
]
},
{
"id": "HNO.00480684.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"tumor"
],
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[
112,
117
]
],
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{
"db_name": "UMLS",
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}
]
},
{
"id": "HNO.00480684.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"skin"
],
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148,
152
]
],
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{
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"db_id": "C0037267"
}
]
},
{
"id": "HNO.00480684.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"cancer"
],
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[
159,
165
]
],
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{
"db_name": "UMLS",
"db_id": "C0006826"
}
]
},
{
"id": "HNO.00480684.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"metastases"
],
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[
205,
215
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0027627"
}
]
},
{
"id": "HNO.00480684.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"prognosis"
],
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239,
248
]
],
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}
]
},
{
"id": "HNO.00480684.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"therapy"
],
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278,
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]
],
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{
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},
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}
]
},
{
"id": "HNO.00480684.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"choice"
],
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[
289,
295
]
],
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}
]
},
{
"id": "HNO.00480684.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"surgery"
],
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[
307,
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]
],
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}
]
},
{
"id": "HNO.00480684.eng.abstr-s4-t4",
"type": "umlsterm",
"text": [
"adjuvant"
],
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[
327,
335
]
],
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{
"db_name": "UMLS",
"db_id": "C0001551"
}
]
},
{
"id": "HNO.00480684.eng.abstr-s4-t5",
"type": "umlsterm",
"text": [
"radiation"
],
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[
336,
345
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0851346"
}
]
}
] |
[] |
[] |
[
{
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},
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},
{
"id": "HNO.00480684.eng.abstr-s1-r4-t2.1-t4.1",
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{
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},
{
"id": "HNO.00480684.eng.abstr-s1-r6-t2.1-t1.1",
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},
{
"id": "HNO.00480684.eng.abstr-s1-r7-t5.1-t7.1",
"type": "location_of",
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},
{
"id": "HNO.00480684.eng.abstr-s1-r8-t5.1-t4.1",
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},
{
"id": "HNO.00480684.eng.abstr-s1-r9-t5.1-t1.1",
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},
{
"id": "HNO.00480684.eng.abstr-s1-r10-t6.1-t2.1",
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},
{
"id": "HNO.00480684.eng.abstr-s1-r11-t6.1-t7.1",
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},
{
"id": "HNO.00480684.eng.abstr-s2-r1-t2.1-t1.1",
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},
{
"id": "HNO.00480684.eng.abstr-s2-r2-t2.1-t1.1",
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"normalized": []
},
{
"id": "HNO.00480684.eng.abstr-s2-r3-t1.1-t2.1",
"type": "associated_with",
"arg1_id": "HNO.00480684.eng.abstr-s4-t1",
"arg2_id": "HNO.00480684.eng.abstr-s4-t2",
"normalized": []
},
{
"id": "HNO.00480684.eng.abstr-s3-r1-t3.1-t1.1",
"type": "associated_with",
"arg1_id": "HNO.00480684.eng.abstr-s4-t3",
"arg2_id": "HNO.00480684.eng.abstr-s4-t1",
"normalized": []
},
{
"id": "HNO.00480684.eng.abstr-s3-r2-t1.1-t3.1",
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"arg2_id": "HNO.00480684.eng.abstr-s4-t3",
"normalized": []
},
{
"id": "HNO.00480684.eng.abstr-s4-r1-t1.1-t3.1",
"type": "method_of",
"arg1_id": "HNO.00480684.eng.abstr-s4-t1",
"arg2_id": "HNO.00480684.eng.abstr-s4-t3",
"normalized": []
},
{
"id": "HNO.00480684.eng.abstr-s4-r2-t1.1-t3.2",
"type": "uses",
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"normalized": []
},
{
"id": "HNO.00480684.eng.abstr-s4-r4-t3.1-t1.1",
"type": "associated_with",
"arg1_id": "HNO.00480684.eng.abstr-s4-t3",
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"normalized": []
},
{
"id": "HNO.00480684.eng.abstr-s4-r5-t5.1-t3.1",
"type": "issue_in",
"arg1_id": "HNO.00480684.eng.abstr-s4-t5",
"arg2_id": "HNO.00480684.eng.abstr-s4-t3",
"normalized": []
},
{
"id": "HNO.00480684.eng.abstr-s4-r6-t3.2-t5.1",
"type": "affects",
"arg1_id": "HNO.00480684.eng.abstr-s4-t3",
"arg2_id": "HNO.00480684.eng.abstr-s4-t5",
"normalized": []
},
{
"id": "HNO.00480684.eng.abstr-s4-r7-t1.1-t3.1",
"type": "associated_with",
"arg1_id": "HNO.00480684.eng.abstr-s4-t1",
"arg2_id": "HNO.00480684.eng.abstr-s4-t3",
"normalized": []
}
] |
HNO.00480689.eng.abstr
|
HNO.00480689.eng.abstr
|
[
{
"id": "HNO.00480689.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The case of a 60-year-old female patient with a supraglottic larynx carcinoma ( T3N2CM0) and bilateral enlargement of the laryngeal sacculus is presented . On one side , the sacculus opened atypically into the left vestibular fold . The sacculus is a physiologic part of the roof of Morgagni's ventricle , the size of which can vary greatly . These canal-like structures can be the point of origin of cysts , laryngoceles , mucoceles , and pyoceles ."
],
"offsets": [
[
0,
450
]
]
}
] |
[
{
"id": "HNO.00480689.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"female"
],
"offsets": [
[
26,
32
]
],
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{
"db_name": "UMLS",
"db_id": "C0086287"
},
{
"db_name": "UMLS",
"db_id": "C0015780"
}
]
},
{
"id": "HNO.00480689.eng.abstr-s1-t2",
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"patient"
],
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33,
40
]
],
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{
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"db_id": "C0030705"
}
]
},
{
"id": "HNO.00480689.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"larynx"
],
"offsets": [
[
61,
67
]
],
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{
"db_name": "UMLS",
"db_id": "C0023078"
},
{
"db_name": "UMLS",
"db_id": "C0007107"
}
]
},
{
"id": "HNO.00480689.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"carcinoma"
],
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[
68,
77
]
],
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{
"db_name": "UMLS",
"db_id": "C0007097"
}
]
},
{
"id": "HNO.00480689.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"enlargement"
],
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[
103,
114
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0020564"
}
]
},
{
"id": "HNO.00480689.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"ventricle"
],
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[
294,
303
]
],
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{
"db_name": "UMLS",
"db_id": "C0018827"
}
]
},
{
"id": "HNO.00480689.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"origin"
],
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[
391,
397
]
],
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"db_id": "C0079946"
}
]
},
{
"id": "HNO.00480689.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"cysts"
],
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401,
406
]
],
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"db_id": "C0010709"
}
]
},
{
"id": "HNO.00480689.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"mucoceles"
],
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[
424,
433
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0026683"
}
]
}
] |
[] |
[] |
[
{
"id": "HNO.00480689.eng.abstr-s1-r1-t3.2-t1.1",
"type": "associated_with",
"arg1_id": "HNO.00480689.eng.abstr-s1-t3",
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"id": "HNO.00480689.eng.abstr-s1-r2-t3.2-t5.1",
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{
"id": "HNO.00480689.eng.abstr-s1-r3-t1.2-t3.2",
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{
"id": "HNO.00480689.eng.abstr-s1-r4-t1.2-t5.1",
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{
"id": "HNO.00480689.eng.abstr-s1-r6-t5.1-t1.2",
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{
"id": "HNO.00480689.eng.abstr-s1-r7-t3.2-t5.1",
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{
"id": "HNO.00480689.eng.abstr-s1-r8-t5.1-t1.1",
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{
"id": "HNO.00480689.eng.abstr-s1-r9-t3.2-t1.1",
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{
"id": "HNO.00480689.eng.abstr-s1-r10-t5.1-t3.2",
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}
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HNO.00480728.eng.abstr
|
HNO.00480728.eng.abstr
|
[
{
"id": "HNO.00480728.eng.abstr-passage-0",
"type": "abstract",
"text": [
"\" Telemedicine \" is a major new development with great potential for improving health care delivery . It therefore affects each department in medicine . There is a great deal of telemedicine activity around the world . However , the term telemedicine is not clear . It describes all forms of medical information , transferred from a relevant distance by an electronic transfer media . An essential condition for communication is the intelligibility between transmitter and receiver . Because of different transmitting technologies and networks in distinct countries , towns , or even academic institutions , satisfactory contact is not possible ."
],
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0,
646
]
]
}
] |
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]
}
] |
[] |
[] |
[
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"id": "HNO.00480728.eng.abstr-s1-r7-t4.1-t2.1",
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}
] |
HNO.00480735.eng.abstr
|
HNO.00480735.eng.abstr
|
[
{
"id": "HNO.00480735.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Background and objective . The majority of inflammatory frontal sinus diseases requiring operative intervention can now be managed successfully by endonasal surgery . In problematic cases , however , optimal exposure of the entire frontal sinus and possibly complete mucous membrane removal combined with sinus obliteration must be achieved . In these cases , external frontal sinus surgery is indicated ."
],
"offsets": [
[
0,
405
]
]
}
] |
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{
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15,
24
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}
]
},
{
"id": "HNO.00480735.eng.abstr-s2-t1",
"type": "umlsterm",
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"sinus"
],
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64,
69
]
],
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"db_id": "C0030471"
}
]
},
{
"id": "HNO.00480735.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"diseases"
],
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[
70,
78
]
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"db_id": "C0012634"
}
]
},
{
"id": "HNO.00480735.eng.abstr-s2-t3",
"type": "umlsterm",
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157,
164
]
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"db_id": "C0038894"
},
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"db_name": "UMLS",
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}
]
},
{
"id": "HNO.00480735.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"frontal sinus"
],
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56,
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}
]
},
{
"id": "HNO.00480735.eng.abstr-s3-t1",
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],
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239,
244
]
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}
]
},
{
"id": "HNO.00480735.eng.abstr-s3-t2",
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"mucous"
],
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267,
273
]
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{
"id": "HNO.00480735.eng.abstr-s3-t3",
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"membrane"
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274,
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231,
244
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}
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{
"id": "HNO.00480735.eng.abstr-s3-t6",
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267,
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{
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}
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},
{
"id": "HNO.00480735.eng.abstr-s4-t3",
"type": "umlsterm",
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369,
382
]
],
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{
"db_name": "UMLS",
"db_id": "C0016734"
}
]
}
] |
[] |
[] |
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{
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HNO.00480743.eng.abstr
|
HNO.00480743.eng.abstr
|
[
{
"id": "HNO.00480743.eng.abstr-passage-0",
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] |
[] |
[] |
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}
] |
HNO.00480747.eng.abstr
|
HNO.00480747.eng.abstr
|
[
{
"id": "HNO.00480747.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Background and objective . The treatment success of nCPAP therapy ( nasal continuous positive airway pressure ) depends partly on the relief of symptoms and partly on long-term patient acceptance and the related avoidance of complications . Nasal complaints constitute the most frequently reported side effects and , together with problems of mask application , are among the primary factors causing an nCPAP-therapy to be prematurely discontinued ."
],
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[
0,
449
]
]
}
] |
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{
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15,
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298,
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{
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}
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}
] |
[] |
[] |
[
{
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{
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}
] |
HNO.00480753.eng.abstr
|
HNO.00480753.eng.abstr
|
[
{
"id": "HNO.00480753.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Background and objective . Defects of the frontal skull base can be reconstructed with different types of material . Homologous material possibly involves the risk of infection and thus complicated wound healing . Therefore , alloplastic material seems to be an interesting alternative ."
],
"offsets": [
[
0,
287
]
]
}
] |
[
{
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{
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"Defects"
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[
27,
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]
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{
"id": "HNO.00480753.eng.abstr-s2-t2",
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"skull"
],
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[
50,
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]
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}
] |
[] |
[] |
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] |
HNO.00480765.eng.abstr
|
HNO.00480765.eng.abstr
|
[
{
"id": "HNO.00480765.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Airbag inflation is associated with a loud noise . This very short noise has a peak amplitude of 170 dB sound pressure level and can make otologic injuries . We report a case of acoustic trauma after airbag inflation . The 24-year-old man has hearing loss both side in the 3000- to 6000-Hz range and in the deep-frequency . The possibility of acoustic trauma from airbag noise are probably much more common and need more attention in the clinic ."
],
"offsets": [
[
0,
446
]
]
}
] |
[
{
"id": "HNO.00480765.eng.abstr-s1-t1",
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"Airbag"
],
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[
0,
6
]
],
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"db_id": "C0162697"
}
]
},
{
"id": "HNO.00480765.eng.abstr-s1-t2",
"type": "umlsterm",
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"inflation"
],
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[
7,
16
]
],
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{
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"db_id": "C0021398"
}
]
},
{
"id": "HNO.00480765.eng.abstr-s1-t3",
"type": "umlsterm",
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"noise"
],
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[
43,
48
]
],
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}
]
},
{
"id": "HNO.00480765.eng.abstr-s2-t1",
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"noise"
],
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[
67,
72
]
],
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{
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"db_id": "C0028263"
}
]
},
{
"id": "HNO.00480765.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"sound"
],
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[
104,
109
]
],
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"db_id": "C0037709"
}
]
},
{
"id": "HNO.00480765.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"pressure"
],
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[
110,
118
]
],
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}
]
},
{
"id": "HNO.00480765.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"injuries"
],
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[
147,
155
]
],
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{
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"db_id": "C0175677"
},
{
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}
]
},
{
"id": "HNO.00480765.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"acoustic"
],
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178,
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]
],
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}
]
},
{
"id": "HNO.00480765.eng.abstr-s3-t2",
"type": "umlsterm",
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"trauma"
],
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[
187,
193
]
],
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{
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"db_id": "C0021501"
},
{
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}
]
},
{
"id": "HNO.00480765.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"airbag"
],
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[
200,
206
]
],
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{
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"db_id": "C0162697"
}
]
},
{
"id": "HNO.00480765.eng.abstr-s3-t4",
"type": "umlsterm",
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"inflation"
],
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[
207,
216
]
],
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}
]
},
{
"id": "HNO.00480765.eng.abstr-s3-t5",
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],
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[
178,
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]
],
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]
},
{
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],
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235,
238
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],
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},
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]
},
{
"id": "HNO.00480765.eng.abstr-s4-t2",
"type": "umlsterm",
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],
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307,
321
]
],
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}
]
},
{
"id": "HNO.00480765.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"hearing loss"
],
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243,
255
]
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},
{
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}
]
},
{
"id": "HNO.00480765.eng.abstr-s5-t1",
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],
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[
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351
]
],
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}
]
},
{
"id": "HNO.00480765.eng.abstr-s5-t2",
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],
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},
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},
{
"id": "HNO.00480765.eng.abstr-s5-t3",
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"airbag"
],
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370
]
],
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}
]
},
{
"id": "HNO.00480765.eng.abstr-s5-t4",
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"noise"
],
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371,
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]
],
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{
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}
]
},
{
"id": "HNO.00480765.eng.abstr-s5-t5",
"type": "umlsterm",
"text": [
"attention"
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[
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]
],
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"db_name": "UMLS",
"db_id": "C0004268"
}
]
},
{
"id": "HNO.00480765.eng.abstr-s5-t6",
"type": "umlsterm",
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"acoustic trauma"
],
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[
343,
358
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0018781"
}
]
}
] |
[] |
[] |
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HNO.00480777.eng.abstr
|
HNO.00480777.eng.abstr
|
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[] |
[] |
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HNO.00480801.eng.abstr
|
HNO.00480801.eng.abstr
|
[
{
"id": "HNO.00480801.eng.abstr-passage-0",
"type": "abstract",
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"In the ancient times , Aristotle , Herophilos , and Galen discovered basic anatomical structures . Paul von Aegina , in the seventh century a. c . , had the idea of a nerve suture , which was first performed in an animal 1000 years later by the Italian surgeon Gabriele Ferrara . Systematic investigations on nerve crossing date to the beginning of the nineteenth century and were conducted by Jean Pierre Flourens . Within 1 week in summer 1864 , two French surgeons ( Laugier and Nélaton ) independently carried out the first nerve sutures in humans . Their observations of an immediate functional recovery of the appropriate muscles after suturing were discussed controversially in scientific circles ."
],
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] |
[] |
[] |
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] |
HNO.00480809.eng.abstr
|
HNO.00480809.eng.abstr
|
[
{
"id": "HNO.00480809.eng.abstr-passage-0",
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HNO.00480816.eng.abstr
|
HNO.00480816.eng.abstr
|
[
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],
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] |
[] |
[] |
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] |
HNO.00480822.eng.abstr
|
HNO.00480822.eng.abstr
|
[
{
"id": "HNO.00480822.eng.abstr-passage-0",
"type": "abstract",
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"Background and objective . The cupula in the ampulla of the semicircular canal , like the tectorial membrane in the cochlea , forms the essential link in transferring endolymph fluid movement stimuli to the hair cells . Clear understanding of physiological cupula movement only started evolving towards the end of the 1970s . Currently , the cupula is assumed to adhere firmly to the ampulla wall , with diaphragm-like displacement in the central section and at the base ."
],
"offsets": [
[
0,
472
]
]
}
] |
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108
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{
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191
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78
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{
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90,
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{
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217
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{
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},
{
"id": "HNO.00480822.eng.abstr-s4-t1",
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418
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]
},
{
"id": "HNO.00480822.eng.abstr-s4-t2",
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],
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431
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}
]
}
] |
[] |
[] |
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HNO.00480828.eng.abstr
|
HNO.00480828.eng.abstr
|
[
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],
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]
]
}
] |
[
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]
}
] |
[] |
[] |
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] |
HNO.00480832.eng.abstr
|
HNO.00480832.eng.abstr
|
[
{
"id": "HNO.00480832.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Background and objective . This study compares the results of the outpatient-based program of the Cochlear Implant Center Ruhr with inpatient-based rehabilitation , which is almost exclusively performed in Germany . Patients/methods . The Department of Otorhinolaryngology at the University of Essen in Germany provided 52 patients with either 22- or 24-channel Nucleus cochlear implants from March 1996 to July 1999. Almost all patients ( n=49) were rehabilitated on an outpatient basis , which is the standard in many cochlear implant centers outside Germany ."
],
"offsets": [
[
0,
562
]
]
}
] |
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{
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{
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{
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{
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{
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{
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{
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{
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]
}
] |
[] |
[] |
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HNO.00480839.eng.abstr
|
HNO.00480839.eng.abstr
|
[
{
"id": "HNO.00480839.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The branchio-oto-renal syndrome ( BOR syndrome ) is characterized by auricular abnormalities , lateral cervical fistulas and preauricular tags . The hearing impairment may be a conductive , a sensorineural or a mixed hearing loss . The renal disease is oligomeganephronia , a bilateral , congenital renal abnormality with reduced numbers of nephrons . The BOR syndrome is an autosomal-dominant disease ."
],
"offsets": [
[
0,
403
]
]
}
] |
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] |
[] |
[] |
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] |
HNO.60440492.eng.abstr
|
HNO.60440492.eng.abstr
|
[
{
"id": "HNO.60440492.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The interval between the onset of symptoms in patients with head and neck cancers and the introduction of treatment was evaluated . During a 1-year period , patients were interviewed to determine the duration of any delays from the onset of complaints until the first visit to a doctor . Also asked was how long it took to be referred to an ENT specialist and actual referral to our department . We then determined the interval from diagnosis to the introduction of therapy . It was found that the delay of patients who went directly to an otorhinolaryngologist was shorter ( median , 8 weeks ) than that of patients who first went to their family doctors ( median , 13 weeks ) ( P 0.02 ) . The latter then took an additional 4 weeks before sending patients to an otorhinolaryngologist . Referral from the ENT specialist to our department took another 2 weeks , as well as our staging and pre-therapeutic management . Our findings show that the patient himself is the critical factor in delaying diagnosis and therapy . Tumor patients with greater professional qualification went to their doctors earlier ( P 0.0001 ) or more often went directly to an ENT specialist ( P 0.002 ) . Consultations of physicians without experience in otorhinolaryngology caused yet further delays ."
],
"offsets": [
[
0,
1278
]
]
}
] |
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] |
[] |
[] |
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HNO.60440497.eng.abstr
|
HNO.60440497.eng.abstr
|
[
{
"id": "HNO.60440497.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The term \" flow motion \" stands for the phenomenon of spontaneous and autonomous rhythmic variations of the contractile state of the smooth muscles of small dermal vessels . There also have been a few observations of variations in the microcirculation of the mucosa , but they have not been evaluated in detail to date . The aims of this study were to develop a method for investigation flow motion , especially in the nasal mucosa ; to compare nasal flow motion to that of other skin and mucosal areas ; to evaluate the influence of normal saline solution , as well as a sympathomimetic agent and histamine on flow motion . The microcirculation of the nasal mucosa of 40 healthy volunteers was measured under standardized conditions . In a first series of investigations , the microcirculations of the forehead , lobule of the ear , nose and oral mucosa were compared . In the second series , the microcirculation of the nasal mucosa was measured with laser-Doppler flowmetry before and after provocation with 0.9% saline solution , 0.25 mg oxymetazoline hydrochloride as sympathicomimetic preparation and 0.085 mg histamine in 0.5 ml of 0.9% saline solution . Evaluation of the data included signal analysis of the microcirculatory variations using fast-Fourier transformation and its changes before and after the pharmacological stimulations . Distribution of the power spectra showed that the nasal mucosa was significantly different from that of the skin of the forehead and the ear . Oxymetazoline hydrochloride led to a clear increase and histamine to a significant reduction in the frequencies of the flow motion . The results of this study demonstrated that nasal flow motion could be detected and evaluated with laser-Doppler flowmetry and a special analysis of the data recorded . Specific patterns of the flow motion frequencies could be detected in the nasal mucosa that were distinctive from those of the skin . The pattern of the flow motion frequencies reacted very sensitively to the pharmacological provocations used ."
],
"offsets": [
[
0,
2036
]
]
}
] |
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{
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{
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{
"id": "HNO.60440497.eng.abstr-s2-t3",
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235,
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{
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{
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] |
[] |
[] |
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HNO.60440503.eng.abstr
|
HNO.60440503.eng.abstr
|
[
{
"id": "HNO.60440503.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Most conditions of the frontal sinus requiring surgery can now be managed successfully by endonasal procedures . To date there has been no clear position regarding indications and results of different types of endonasal frontal sinus drainage . In a retrospective study we evaluated long-term results of Draf's type II and III endonasal frontal sinus drainages using endoscopy and computed tomography . Twelve to 98 months following type II drainage , 58% of 83 frontal sinuses were ventilated and normal . A ventilated frontal sinus but with hyperplastic mucosa was seen in 12% . Scarred occlusion with total opacification on CT occurred in 14% . Furthermore , total opacification in 16% was due to recurrent polyposis . Patients were free of symptoms or had only minor problems in 79% . Twelve to 89 months following type III drainage , 59% of 81 frontal sinuses were ventilated and normal . A ventilated frontal sinus with hyperplastic mucosa was seen in 17% . Scarred occlusion with total opacification on CT was present in 7% . Furthermore , total opacification in 16% was due to recurrent polyposis . In all , 95% of the patients were free of symptoms or had only minor problems . Combining our results with those of other authors and utilizing the physiology of wound healing after sinus surgery , we developed a protocol of differential indications for endonasal frontal sinus drainage ."
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[] |
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] |
HNO.60440510.eng.abstr
|
HNO.60440510.eng.abstr
|
[
{
"id": "HNO.60440510.eng.abstr-passage-0",
"type": "abstract",
"text": [
"During surgical resections carotid body tumors may bleed profusely due to their vascularity . Preoperative angiographic embolization of tumor-supplying arteries has reduced intraoperative blood loss significantly . The present study reviews our clinical experiences with 13 paragangliomas of the carotid bifurcation in 12 patients during the past 5 years . In 6 patients ( 46.1% ) computed tomography and magnetic resonance imaging demonstrated extensive spread of the tumor up to the base of the skull . Tumors of this size were initially assessed as being inoperable but curative surgical resections were performed after embolization of tumor-supplying arteries by intravascular injections of Gelfoam and implantations of microcoils . Vascular reconstruction of the internal carotid artery by a saphenous vein graft was required in 4 patients ( 30.7% ) . In 3 malignant paragangliomas ( 23.0% ) adjuvant radiotherapy of 50-60 Gy was administered to the tumor site after surgery . During an average follow-up of 29 months , one malignant paraganglioma was found to have recurred locally 13 months after initial therapy ."
],
"offsets": [
[
0,
1121
]
]
}
] |
[
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],
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15
]
],
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}
]
},
{
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"tumors"
],
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[
40,
46
]
],
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}
]
},
{
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],
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[
27,
39
]
],
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}
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{
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],
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27,
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{
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],
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}
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},
{
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],
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152,
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]
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},
{
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{
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}
]
},
{
"id": "HNO.60440510.eng.abstr-s2-t4",
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],
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188,
198
]
],
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{
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}
]
},
{
"id": "HNO.60440510.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"paragangliomas"
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] |
[] |
[] |
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HNO.60440514.eng.abstr
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HNO.60440514.eng.abstr
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"Following curative minimal-invasive laser resection of T1-T3 laryngeal carcinomas , patients were subjected to an intensive voice rehabilitation . Therapy was effected twice a day for approximately 2 months , utilizing the concept of functional voice therapy . Before and after rehabilitation , acoustic analyses were made by using two different computer-supported measuring systems : ( 1 ) the \" multidimensional voice program \" ( Kay Elementrics Corp. ) and ( 2 ) a novel software program developed in Goettingen that includes a new voice quality parameter based on correlations between frequency bands . Acoustic analyses showed superiority of the glottal versus supraglottal compensatory phonation . Findings showed that not all acoustic parameters equally documented voice improvement after rehabilitation . The standard deviation of fundamental frequency was the only parameter showing a significant post-therapeutic improvement . A further suitable acoustic method proved to be the voice quality parameter that has been newly introduced by us . In contrast to analogous parameters of other methods , this approach is independent of the exact periodicity of the glottal excitation function , thus permitting reliable results to be obtained even with aphonic or heavily dysphonic voices ."
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[] |
[] |
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] |
HNO.60440521.eng.abstr
|
HNO.60440521.eng.abstr
|
[
{
"id": "HNO.60440521.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Klippel-Feil syndrome is characterized by a short-neck and a low occipital hairline due to such deformaties of the cervical spine as aplasia , dysplasia and fusions of the cervical and thoracic vertebrae . Approximately 1/3 of cases have sensorineural deafness , although occasional unilateral or bilateral conductive hearing loss due to middle ear malformations have been described ."
],
"offsets": [
[
0,
384
]
]
}
] |
[
{
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],
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13,
21
]
],
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}
]
},
{
"id": "HNO.60440521.eng.abstr-s1-t2",
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"short-neck"
],
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[
44,
54
]
],
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{
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"db_id": "C0027530"
}
]
},
{
"id": "HNO.60440521.eng.abstr-s1-t3",
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"hairline"
],
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[
75,
83
]
],
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}
]
},
{
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],
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[
75,
83
]
],
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{
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}
]
},
{
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}
] |
[] |
[] |
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}
] |
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