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HNO.60440526.eng.abstr
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HNO.60440526.eng.abstr
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"Until now reports of factitious disease have not been found in the ENT literature . In contrast , the dermatologic literature estimates an incidence from 0.01 to 0.26% . In order to achieve effective treatment for these patients , knowledge of the characteristic symptoms is fundamental . The present paper describes the variety of disease possible , using three cases treated between 1992 and 1994 in the ENT Department of Cologne . According to the literature , females are involved in a ratio of 9:1 , with the majority working in medically related professions . Depression and anorexia are typical symptoms . When a factitious disease is suspected , psychiatric consultation is essential . Confrontation of a suspect patient by the otolaryngologist is not often considered because several reports quote suicidal behavior in up to 25% of self-manipulating patients and tendencies to refuse to follow psychiatric treatment are considerable ."
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[] |
[] |
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HNO.60440559.eng.abstr
|
HNO.60440559.eng.abstr
|
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"id": "HNO.60440559.eng.abstr-passage-0",
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"The brainstem auditory evoked responses ( BAERs ) of 87 patients with chronic renal failure ( average age 51 years ) were examined according to serum creatinine levels , the nature of the chronic renal disease present and the effect of dialysis . Changes recorded were followed over a period of 3 years . Altogether BAERs of 272 ears were evaluated . Results demonstrated changes in wave morphology and abnormal prolongations of all wave latencies and interpeak intervals . Wave V latencies and the interpeak interval for waves I-V showed a correlation to serum creatinine levels . The direct positive effect of dialysis was reflected in shortening of all wave latencies . The nature of the chronic renal disease and the existence of coexistence diseases were not important for changes in central BAER responses . The recording of the intra-individual course of a BAER permitted documentation of worsened cerebral function even in patients with constant uremic conditions ."
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] |
HNO.60440567.eng.abstr
|
HNO.60440567.eng.abstr
|
[
{
"id": "HNO.60440567.eng.abstr-passage-0",
"type": "abstract",
"text": [
"During ENT surgical procedures under general anesthesia contamination of the operating room air through waste anesthetic gases seems unavoidable . A resulting chronic low-level exposure to anesthetic gases in subanesthetic concentrations ( ml/m3=ppm) may cause various negative health effects . The aim of this study was to quantify possible side effects on operating room personnel . By using a highly sensitive , direct reading instrument for determining contamination leakage from a patient's mouth and resulting concentrations in the breathing zone of the surgeon and anesthetist , levels of isoflurane and nitrous oxide were measured at 2-min intervals during 20 ENT surgical procedures performed under usual workplace conditions . Despite high concentrations of anesthetic at the mouth of each patient , personnel-related mean values remained under recommended threshold values ( TLV ) of 10 ppm isoflurane . A TLV of 100 ppm nitrous oxide was exceeded in 20% of the operations . Furthermore , a safe TLV for pregnant staff was 25 ppm nitrous oxide . This value was exceeded during nearly all operations ( 93% ) for the group \" surgeon \" . High leakages at the patient's mouth led to an undesirably high contamination of operating room personnel by nitrous oxide . Although threshold values were mostly not exceeded in available working conditions ( i.e. , adequate air conditioning and intubation cuff pressure control ) , present health and safety regulations concerning pregnant women showed that the values of nitrous oxide were still too high to allow such women to work safely in operating rooms during surgery . However , exposure to isoflurane was too slight to classify ."
],
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0,
1686
]
]
}
] |
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] |
[] |
[] |
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HNO.60440585.eng.abstr
|
HNO.60440585.eng.abstr
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[
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"type": "abstract",
"text": [
"Profiles of fundamental frequency sound pressure levels and voice duration are measured separately in clinical practice . It was the aim of the present study to combine the two examinations , in order to estimate the relationship between pitch , sound pressure level and voice duration and to develop a new computer-assisted graph . A three-dimensional ( 3D ) wireframe phonogram was constructed based on SPL profiles to obtain a general view of the parameters recorded . We have termed this \" phonetography \" . Variable further projections were selected for the analysis of different aspects of parametric relationships . The results in 21 healthy volunteers and 4 patients with hyperfunctional dysphonias demonstrated that there were three typical figures of the 3D phonograms produced , depending on the relationship between voice duration when soft ( \" piano \" ) compared to loud ( \" forte \" ) . In one-third of the healthy volunteers , the values of the piano voice duration were greater than those of forte for almost all pitches examined . In two-thirds of the healthy subjects the values of forte voice duration were partly greater , as were those of piano voice duration . All of the patients showed voice duration values greater for forte than for piano . The results of the study demonstrate that the 3D phonogram is a useful tool for obtaining new insights into various relationships of voice parameters ."
],
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[
0,
1417
]
]
}
] |
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{
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]
},
{
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{
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{
"id": "HNO.60440585.eng.abstr-s9-t3",
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],
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1209,
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]
},
{
"id": "HNO.60440585.eng.abstr-s10-t1",
"type": "umlsterm",
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],
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[
1399,
1404
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0042939"
}
]
}
] |
[] |
[] |
[
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{
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{
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{
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},
{
"id": "HNO.60440585.eng.abstr-s6-r1-t3.1-t4.1",
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},
{
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},
{
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"normalized": []
},
{
"id": "HNO.60440585.eng.abstr-s6-r4-t1.1-t2.1",
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},
{
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},
{
"id": "HNO.60440585.eng.abstr-s6-r6-t1.1-t3.1",
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},
{
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"normalized": []
},
{
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},
{
"id": "HNO.60440585.eng.abstr-s7-r1-t4.1-t2.1",
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},
{
"id": "HNO.60440585.eng.abstr-s9-r1-t1.1-t3.1",
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},
{
"id": "HNO.60440585.eng.abstr-s9-r2-t1.1-t2.1",
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},
{
"id": "HNO.60440585.eng.abstr-s9-r3-t3.1-t1.1",
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"arg2_id": "HNO.60440585.eng.abstr-s10-t1",
"normalized": []
}
] |
HNO.60440590.eng.abstr
|
HNO.60440590.eng.abstr
|
[
{
"id": "HNO.60440590.eng.abstr-passage-0",
"type": "abstract",
"text": [
"We report an unusual injury of the face caused by the spoke of an automatic telescoping umbrella that come loose when the umbrella was opened . Due to the shot-like force of the spoke , the left nostril , septum and right wall of the nasal cavity were pierced . The part with the joint penetrated into the maxillary antrum . In order to remove the spoke , wire scissors had to be used to cuff off the spoke's joint inside the surgically opened maxillary sinus ."
],
"offsets": [
[
0,
461
]
]
}
] |
[
{
"id": "HNO.60440590.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"injury"
],
"offsets": [
[
21,
27
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0175677"
},
{
"db_name": "UMLS",
"db_id": "C0021501"
}
]
},
{
"id": "HNO.60440590.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"face"
],
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[
35,
39
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0015450"
}
]
},
{
"id": "HNO.60440590.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"right"
],
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[
216,
221
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0035621"
}
]
},
{
"id": "HNO.60440590.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"nasal cavity"
],
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[
234,
246
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0027423"
}
]
},
{
"id": "HNO.60440590.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"joint"
],
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[
280,
285
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0022417"
}
]
},
{
"id": "HNO.60440590.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"maxillary"
],
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[
306,
315
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0024947"
}
]
},
{
"id": "HNO.60440590.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"maxillary antrum"
],
"offsets": [
[
306,
322
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0024957"
}
]
},
{
"id": "HNO.60440590.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"wire"
],
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[
356,
360
]
],
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{
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"db_id": "C0005978"
}
]
},
{
"id": "HNO.60440590.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"spoke's"
],
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[
401,
408
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0605770"
}
]
},
{
"id": "HNO.60440590.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"joint"
],
"offsets": [
[
409,
414
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0022417"
}
]
},
{
"id": "HNO.60440590.eng.abstr-s4-t4",
"type": "umlsterm",
"text": [
"maxillary"
],
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[
444,
453
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0024947"
}
]
},
{
"id": "HNO.60440590.eng.abstr-s4-t5",
"type": "umlsterm",
"text": [
"sinus"
],
"offsets": [
[
454,
459
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030471"
}
]
},
{
"id": "HNO.60440590.eng.abstr-s4-t6",
"type": "umlsterm",
"text": [
"maxillary sinus"
],
"offsets": [
[
444,
459
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0024957"
}
]
}
] |
[] |
[] |
[
{
"id": "HNO.60440590.eng.abstr-s1-r1-t1.1-t1.2",
"type": "location_of",
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"normalized": []
},
{
"id": "HNO.60440590.eng.abstr-s3-r1-t3.1-t2.1",
"type": "connected_to",
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},
{
"id": "HNO.60440590.eng.abstr-s3-r2-t1.1-t2.1",
"type": "connected_to",
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"arg2_id": "HNO.60440590.eng.abstr-s4-t2",
"normalized": []
},
{
"id": "HNO.60440590.eng.abstr-s3-r3-t2.1-t3.1",
"type": "interconnects",
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},
{
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},
{
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},
{
"id": "HNO.60440590.eng.abstr-s4-r2-t4.1-t5.1",
"type": "interconnects",
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"arg2_id": "HNO.60440590.eng.abstr-s4-t5",
"normalized": []
},
{
"id": "HNO.60440590.eng.abstr-s4-r3-t5.1-t4.1",
"type": "connected_to",
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},
{
"id": "HNO.60440590.eng.abstr-s4-r4-t2.1-t4.1",
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},
{
"id": "HNO.60440590.eng.abstr-s4-r5-t6.1-t4.1",
"type": "connected_to",
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"normalized": []
},
{
"id": "HNO.60440590.eng.abstr-s4-r6-t4.1-t6.1",
"type": "interconnects",
"arg1_id": "HNO.60440590.eng.abstr-s4-t4",
"arg2_id": "HNO.60440590.eng.abstr-s4-t6",
"normalized": []
},
{
"id": "HNO.60440590.eng.abstr-s4-r7-t4.1-t2.1",
"type": "interconnects",
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"arg2_id": "HNO.60440590.eng.abstr-s4-t2",
"normalized": []
}
] |
HNO.60440592.eng.abstr
|
HNO.60440592.eng.abstr
|
[
{
"id": "HNO.60440592.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The Q-switched ruby laser ( wave length 694 nm ; pulse durations 25 ns or 40 ns ) causes selective damage to natural and artificial skin pigments . Treatable lesions include benign pigmented growths ( benign lentigo , ephelides , café-au-lait spots and Becker's nevi ) , as well as amateur and professional tattoos . The Q-switched ruby laser is also very effective in the treatment of traumatic tattoos . We report our experiences with two patients whose traumatic tattoos resolved completely without any scarring after ruby laser therapy . Our findings show that Q-switched ruby laser treatment may represent the therapy of choice for these tattoos ."
],
"offsets": [
[
0,
652
]
]
}
] |
[
{
"id": "HNO.60440592.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"laser"
],
"offsets": [
[
20,
25
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0023089"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"pulse"
],
"offsets": [
[
49,
54
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0034107"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"skin"
],
"offsets": [
[
132,
136
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0037267"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"pigments"
],
"offsets": [
[
137,
145
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0031916"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"artificial skin"
],
"offsets": [
[
121,
136
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0206238"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"growths"
],
"offsets": [
[
191,
198
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0018270"
},
{
"db_name": "UMLS",
"db_id": "C0220844"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"lentigo"
],
"offsets": [
[
208,
215
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0023321"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"spots"
],
"offsets": [
[
243,
248
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0015230"
},
{
"db_name": "UMLS",
"db_id": "C0312414"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"Becker's"
],
"offsets": [
[
253,
261
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0605770"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"nevi"
],
"offsets": [
[
262,
266
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0027960"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s2-t6",
"type": "umlsterm",
"text": [
"tattoos"
],
"offsets": [
[
307,
314
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0039343"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"laser"
],
"offsets": [
[
337,
342
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0023089"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"treatment"
],
"offsets": [
[
373,
382
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0087111"
},
{
"db_name": "UMLS",
"db_id": "C0039798"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"tattoos"
],
"offsets": [
[
396,
403
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0039343"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"patients"
],
"offsets": [
[
441,
449
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"laser"
],
"offsets": [
[
526,
531
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0023089"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"therapy"
],
"offsets": [
[
532,
539
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0087111"
},
{
"db_name": "UMLS",
"db_id": "C0039798"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"findings"
],
"offsets": [
[
546,
554
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0243095"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"laser"
],
"offsets": [
[
581,
586
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0023089"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s5-t3",
"type": "umlsterm",
"text": [
"treatment"
],
"offsets": [
[
587,
596
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0087111"
},
{
"db_name": "UMLS",
"db_id": "C0039798"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s5-t4",
"type": "umlsterm",
"text": [
"therapy"
],
"offsets": [
[
615,
622
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0087111"
},
{
"db_name": "UMLS",
"db_id": "C0039798"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s5-t5",
"type": "umlsterm",
"text": [
"choice"
],
"offsets": [
[
626,
632
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0008300"
}
]
},
{
"id": "HNO.60440592.eng.abstr-s5-t6",
"type": "umlsterm",
"text": [
"tattoos"
],
"offsets": [
[
643,
650
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0039343"
}
]
}
] |
[] |
[] |
[
{
"id": "HNO.60440592.eng.abstr-s1-r1-t2.1-t3.1",
"type": "measures",
"arg1_id": "HNO.60440592.eng.abstr-s5-t2",
"arg2_id": "HNO.60440592.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s1-r2-t2.1-t1.1",
"type": "uses",
"arg1_id": "HNO.60440592.eng.abstr-s5-t2",
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"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s1-r3-t5.1-t4.1",
"type": "interacts_with",
"arg1_id": "HNO.60440592.eng.abstr-s5-t5",
"arg2_id": "HNO.60440592.eng.abstr-s5-t4",
"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s1-r4-t2.1-t5.1",
"type": "analyzes",
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"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s1-r5-t2.1-t4.1",
"type": "analyzes",
"arg1_id": "HNO.60440592.eng.abstr-s5-t2",
"arg2_id": "HNO.60440592.eng.abstr-s5-t4",
"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s1-r6-t3.1-t2.1",
"type": "location_of",
"arg1_id": "HNO.60440592.eng.abstr-s5-t3",
"arg2_id": "HNO.60440592.eng.abstr-s5-t2",
"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s1-r7-t4.1-t5.1",
"type": "interacts_with",
"arg1_id": "HNO.60440592.eng.abstr-s5-t4",
"arg2_id": "HNO.60440592.eng.abstr-s5-t5",
"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s2-r1-t3.2-t1.1",
"type": "affects",
"arg1_id": "HNO.60440592.eng.abstr-s5-t3",
"arg2_id": "HNO.60440592.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s2-r2-t1.2-t3.2",
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"normalized": []
},
{
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"type": "result_of",
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},
{
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"type": "degree_of",
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"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s2-r5-t1.1-t1.2",
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"normalized": []
},
{
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},
{
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},
{
"id": "HNO.60440592.eng.abstr-s2-r9-t4.1-t3.1",
"type": "affects",
"arg1_id": "HNO.60440592.eng.abstr-s5-t4",
"arg2_id": "HNO.60440592.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s2-r10-t6.1-t1.2",
"type": "associated_with",
"arg1_id": "HNO.60440592.eng.abstr-s5-t6",
"arg2_id": "HNO.60440592.eng.abstr-s2-t1",
"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s2-r11-t3.2-t1.2",
"type": "affects",
"arg1_id": "HNO.60440592.eng.abstr-s5-t3",
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},
{
"id": "HNO.60440592.eng.abstr-s2-r12-t1.2-t1.1",
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},
{
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"type": "associated_with",
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"arg2_id": "HNO.60440592.eng.abstr-s2-t1",
"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s2-r15-t3.1-t1.1",
"type": "result_of",
"arg1_id": "HNO.60440592.eng.abstr-s5-t3",
"arg2_id": "HNO.60440592.eng.abstr-s5-t1",
"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s2-r16-t3.2-t1.2",
"type": "degree_of",
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"arg2_id": "HNO.60440592.eng.abstr-s2-t1",
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},
{
"id": "HNO.60440592.eng.abstr-s2-r17-t1.2-t6.1",
"type": "associated_with",
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},
{
"id": "HNO.60440592.eng.abstr-s2-r18-t3.2-t1.1",
"type": "result_of",
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},
{
"id": "HNO.60440592.eng.abstr-s2-r19-t4.1-t1.1",
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},
{
"id": "HNO.60440592.eng.abstr-s2-r20-t4.1-t3.2",
"type": "affects",
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},
{
"id": "HNO.60440592.eng.abstr-s2-r21-t1.2-t3.1",
"type": "associated_with",
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"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s2-r22-t3.1-t1.1",
"type": "evaluation_of",
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},
{
"id": "HNO.60440592.eng.abstr-s2-r25-t3.1-t1.2",
"type": "associated_with",
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},
{
"id": "HNO.60440592.eng.abstr-s2-r26-t3.2-t1.1",
"type": "evaluation_of",
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"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s2-r27-t6.1-t3.1",
"type": "associated_with",
"arg1_id": "HNO.60440592.eng.abstr-s5-t6",
"arg2_id": "HNO.60440592.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s2-r28-t3.2-t6.1",
"type": "associated_with",
"arg1_id": "HNO.60440592.eng.abstr-s5-t3",
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"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s2-r29-t4.1-t1.2",
"type": "affects",
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},
{
"id": "HNO.60440592.eng.abstr-s2-r30-t1.1-t3.2",
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},
{
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},
{
"id": "HNO.60440592.eng.abstr-s4-r1-t1.1-t2.1",
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},
{
"id": "HNO.60440592.eng.abstr-s4-r2-t3.1-t2.1",
"type": "uses",
"arg1_id": "HNO.60440592.eng.abstr-s5-t3",
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"normalized": []
},
{
"id": "HNO.60440592.eng.abstr-s4-r3-t3.1-t1.1",
"type": "affects",
"arg1_id": "HNO.60440592.eng.abstr-s5-t3",
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},
{
"id": "HNO.60440592.eng.abstr-s4-r4-t1.1-t3.1",
"type": "performs",
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"arg2_id": "HNO.60440592.eng.abstr-s5-t3",
"normalized": []
}
] |
HNO.60440612.eng.abstr
|
HNO.60440612.eng.abstr
|
[
{
"id": "HNO.60440612.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The results of 13 single-stage reconstructions of large and complex defects in the head and neck by using eight free radial forearm flaps as well as five pectoralis major myocutaneous flaps were analyzed . No complete flap loss occurred in any case . The results with radial forearm flap reconstructions proved to be better functionally and aesthetically . Due to the time needed for the microvascular anastomoses , the length of the operations was sometimes prolonged . Pectoralis major flaps were found to be more difficult to handle and were used in those cases in which the application of free radial forearm flaps was expected to produce higher risks ."
],
"offsets": [
[
0,
657
]
]
}
] |
[
{
"id": "HNO.60440612.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"single-stage"
],
"offsets": [
[
18,
30
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0087136"
}
]
},
{
"id": "HNO.60440612.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"single-stage"
],
"offsets": [
[
18,
30
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0027646"
}
]
},
{
"id": "HNO.60440612.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"defects"
],
"offsets": [
[
68,
75
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0243067"
}
]
},
{
"id": "HNO.60440612.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"head"
],
"offsets": [
[
83,
87
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0018670"
}
]
},
{
"id": "HNO.60440612.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"neck"
],
"offsets": [
[
92,
96
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0027530"
}
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] |
[] |
[] |
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HNO.60440616.eng.abstr
|
HNO.60440616.eng.abstr
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[
{
"id": "HNO.60440616.eng.abstr-passage-0",
"type": "abstract",
"text": [
"It remains a controversial question whether or not the anastomosis of sensory nerves is necessary in free transplants of microvasculary reanastomosed radial forearm flaps in the oral cavity and oropharynx . Some authors perform this routinely because they expect fewer complications in a skin with a sensory nerve supply . We carried out clinical and morphological examinations in 20 patients in order to determine the sensory innervation of the transplanted tissue . All patients received free transplants of microvasculary reanastomosed radial forearm flaps during a tumor operation in the oral cavity or oropharynx . Postoperative wound healing proceeded without complications in all but three cases , but these disturbances were insufficient to explain any deficit in sensation in the operated areas . Following surgery , sensation was determined clinically by two-point discrimination . Morphological studies of 20 flap biopsies using conventional colored light microscopy demonstrated nerve fibers in 14 of the biopsies . Immunohistochemical investigations also showed the presence of small nerve fibers by proving S-100 positive Schwann cells . We could not find a correlation between the demonstration of nerve fibers and the use of radiation ( or an increased radiation dosage ) following surgery . These findings suggest that nerve regeneration was completed just before the 6th postoperative month , which was the earliest time recorded in this study . Perivascular ( vegetative ) nerves showed a delayed regeneration and could be demonstrated only 36 months after operation . Histological investigations of the transplanted tissue showed a decrease in keratin with a partial increase in parakeratosis , a loss of skin structures and nearly always chronic inflammation . Our findings verify that a sensory innervation is possible in free transplanted radial forearm flaps by the regeneration of nerves coming from the transplantation bed and/or adjacent ( oral ) mucosa . This leads to a sensation comparable to that of healthy mucosa . These findings also indicate that there is no need for the anastomosis of sensory nerves during transplant surgery ."
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] |
[] |
[] |
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HNO.60440624.eng.abstr
|
HNO.60440624.eng.abstr
|
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HNO.60440630.eng.abstr
|
HNO.60440630.eng.abstr
|
[
{
"id": "HNO.60440630.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Isolated hair cell preparations have gained wide acceptance as a model for studying physiological and molecular properties of the sensory cells involved in the hearing process . Ultrastructural details , such as stereocilia links , lateral membrane substructure or synaptic links are of crucial importance for normal sensory transduction . For this reason , we developed a high-resolution scanning electron microscopy ( SEM ) procedure to study the surface of isolated hair cells . Cells were mechanically and/or enzymatically separated , isolated and immobilized on cover slips by alcian blue and fixed by 2% glutardialdehyde or 1% OsO4. After dehydration , preparations were critical point-dried and sputter-coated with gold-palladium ( 2-4 nm ) . Up to 5 nm resolution was achieved . Optimal fixation kept the cells in their typical cylindrical forms . Preservation of the stereocilia and the apical plates of the outer hair cells depended strongly on the fixation process . Tip- and side-links were observed only sporadically because of the aggressive preparation procedure . The lateral plasma membranes of the cell bodies showed regular granular structures of 5-7 nm diameter at maximal magnification . The granular structure of the cell membrane seemed to correspond to putataive transmembrane proteins believed to generate membrane-based motility . The remnants of the nerve endings and/or supporting cells usually covered the cell base . The preservation of the cells was better when enzymatic isolation was omitted . The technique used allowed for high resolution ultrastructural examination of isolated hair cells and , when combined with immunological labeling , may permit the identification of proteins at a molecular level ."
],
"offsets": [
[
0,
1739
]
]
}
] |
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] |
[] |
[] |
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] |
HNO.60440634.eng.abstr
|
HNO.60440634.eng.abstr
|
[
{
"id": "HNO.60440634.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Radical orofacial tumor resections often result in speech and swallowing dysfunctions . Thus , both communication ability and life quality can be markedly impaired in patients . Dysfunction is mostly related to the amount of tissue removed and the reconstruction technique used . In this prospective study , pre- and postoperative speech intelligibility following reconstruction with either local grafts , free jejunal flaps or myocutaneous/fasciocutaneous flaps was examined by subjective assessment of monosyllables chosen from the Freiburg audiometry test ( \" reverse speech intelligibility test \" ) . It was shown that linguodental affricates and dorsofaucal plosives were especially affected , even preoperatively , in patients with T3 and T4 tumors , while additional deterioration of speech function occurred postoperatively . When comparing reconstruction techniques , use of local grafts showed less postoperative deterioration in the patients with T3 and T4 tumors ( expert rating/student rating -5 . 0% +/- -3 . 8% ) , whereas impairment was much more evident when jejunal flaps ( expert rating/student rating -27 . 9% +/- -35 . 1% ) and myocutaneous and fasciocutaneous flaps ( expert rating/student rating -34 . 2% +/- -48 . 1% ) were used . Results demonstrated that patients should be informed about negative side effects following radical tumor resections and reconstructions of large tissue defects . Surgery should avoid marked motor and sensory nerve lesions whenever possible . Before speech therapy is begun , speech function should be examined carefully . Speech intelligibility should also be documented , e.g. with audio tapes , for quality assessment ."
],
"offsets": [
[
0,
1677
]
]
}
] |
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57
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{
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138
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{
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178,
189
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{
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] |
HNO.60440661.eng.abstr
|
HNO.60440661.eng.abstr
|
[
{
"id": "HNO.60440661.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Surgical therapy of cervical lymph node metastasis is based on their accessibility for en bloc resections . First described by Crile in 1906 as a radical neck dissection , this original approach has since undergone various modifications . This has produced an ongoing controversy with regard to the indications of the individual techniques . In a retrospective study , the data of 438 patients with head and neck malignancies managed at the ENT Department of Hamburg University between 1988 and 1994 were analyzed after surgical treatment of cervical lymph nodes . Results showed that 337 patients ( 76.9% ) required unilateral or bilateral selective neck dissections . In 101 patients ( 23.1% ) in whom a radical neck dissection was performed , the sternocleidomastoid muscle was resected completely . Analysis of these cases showed that intraoperative macroscopic invasion occurred in 12 patients ( 11.9% ) and was confirmed histologically . The vast majority of cases ( n=89; 88.1% ) had an intact muscle resected without tumor involvement . Further analysis showed no difference between radically or functionally neck-dissected stage III or IV patients with oral cavity , oropharyngeal , hypopharyngeal and laryngeal carcinomas . On the basis of these findings , resection of the sternocleidomastoid muscle is not mandatory in patients undergoing primary surgery without previous ( cervical ) radiation and when the muscle is found to be macroscopically intact ."
],
"offsets": [
[
0,
1466
]
]
}
] |
[
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0,
8
]
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{
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9,
16
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{
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] |
[] |
[] |
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] |
HNO.60440672.eng.abstr
|
HNO.60440672.eng.abstr
|
[
{
"id": "HNO.60440672.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The effects of peritonsillar injections of epinephrine and local anesthetics before tonsillectomy on blood loss and postoperative pain were evaluated in a prospective , randomized double-blind trial on 103 children . Patients were randomly assigned into one of three groups : controls given injections of 0.9% NaCl ( n=34), patients injected with 0.4 ml/kg ( 1:200 , 000 ) epinephrine combined with 0.25% bupivacaine ( n=33) and patients given only 1:200 , 000 epinephrine ( n=36). All injections and operations were performed by the same surgeon ( KS ) . Blood loss was calculated by weighing all blood aspirated perioperatively and swabs used during surgery . Postoperative pain was assessed at regular intervals by using three methods : ( 1 ) use of a visual analogue scale by parents and nurses to estimate pain ; ( 2 ) postoperative need for nalbuphin as analgesic ; ( 3 ) the Hannallah-Broadman semi-objective pain score ( including crying , anxiety , restlessness , and changes in blood pressure ) . The mean blood loss in the control group ( given NaCl ) was 132 g , which was significantly increased when compared with the epinephrine/bupivacaine group ( 85 g ) and the group treated with only epinephrine ( 90 g ) . However , analysis of the postoperative pain scores did not reveal any significant differences among groups . These findings indicate that the peritonsillar injection of bupivacaine does not decrease postoperative pain , but peritonsillar injections of epinephrine will significantly reduce blood loss during tonsillectomy ."
],
"offsets": [
[
0,
1550
]
]
}
] |
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{
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],
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43,
54
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],
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],
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]
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{
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],
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[
206,
214
]
],
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},
{
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],
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{
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],
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]
],
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] |
[] |
[] |
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HNO.60440677.eng.abstr
|
HNO.60440677.eng.abstr
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"Unilateral hearing loss ( HL ) caused by an acoustic neuroma ( AN ) is regarded to be neural ( \" non-cochlear \" ) . By using otoacoustic emissions it is possible to prove concurrent sensory ( cochlear ) HL . We prefer distortion-product otoacoustic emissions ( DPOAE ) because these are more frequency-specific and stable . From April 1994 to May 1996 , we examined preoperatively 24 patients with radiologically proven AN . Pure-tone audiometry , DP-grams , brainstem-evoked response audiometry ( BERA ) and vestibular studies were performed in all cases , while special auditory tests ( Fowler , Carhart ) and short increment sensitivity indices were also performed in 12 cases . BERA was pathological in 23 cases and latencies were borderline in one case . After comparing audiograms and DP-grams we found 13 patients with sensory HL , 4 patients with combined sensorineural HL and 7 patients with neural HL . There was a strong correlation between the results of DPOAE and the results of special auditory test ( =0 . 63 ) whereas there was no correlation between tumor size and cochlear function . The result showed that the typical HL caused by AN was a combined sensorineural loss . DPOAE were not suited for the detection of AN but were able to give exact information about any remaining cochlear function ."
],
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0,
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]
}
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[] |
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HNO.60440685.eng.abstr
|
HNO.60440685.eng.abstr
|
[
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"type": "abstract",
"text": [
"Vocal fold vibration patterns during phonation are presented with different digital imaging systems . With newly developed technical equipment color images up to 1000 digital images/s were obtained without light intensifying enhancement techniques via rigid and flexible endoscopy . With this color high-speed system , morphologic structures , such as small blood vessels , were visualized in high-resolution quality as a result of additional color information . In another system , zooming of endoscopic pictures via pixel interpolation algorithms provided full-monitor presentation of vocal fold vibratory patterns . This system allows PC-based synchronization with microphone and electroglottographic signals in a frame-by-frame technique . Although only processing gray scale images , analyses of dynamic changes in modes of vibration were faciliated by the higher frame rate recording of up to 2000 frames/s and , in addition , they display corresponding analog signals . Both methods provide clinically important information . Furthermore , we demonstrated irregular vocal fold vibration patterns in a healthy adult volunteer . In this experiment , the irregular vibratory modes were induced by voluntarily applying asymmetric vocal fold tension . The asymmetric vocal fold vibration pattern resulted in ( functionally induced ) roughness of the voice as predicted by computer models of asymmetric vocal fold vibration . Digital high-speed cinematography proved to be a highly promising technique in the analysis of dysphonia and provided physiological examples that could be compared with models of coupled nonlinear oscillators ."
],
"offsets": [
[
0,
1637
]
]
}
] |
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] |
[] |
[] |
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HNO.60440694.eng.abstr
|
HNO.60440694.eng.abstr
|
[
{
"id": "HNO.60440694.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Vincent's angina ( Plaut-Vincent ) is the most prominent disease caused by coinciding infections from fusibacteria and spirochaeta both belonging to obligate anaerobic bacterias . A possible symbiotic infection of both anaerobics may become manifest on the mucous membranes of the oral cavity and the oropharynx beside the tonsillas . The clinical outcome may be different and pose difficulties in the differential diagnosis . We report the case of a 29 year old female patient with necrotizing ulcera of the soft palate suspicious for stomatitis ulceromembranacea . In case necrotizing inflammations of the oral cavity area were to be found infections due to anaerobic bacterias should be considered mostly occuring as mixed infections . The correct identification by cultivation turnes out to be difficult in that it requires special conditions . Furthermore , reliable detection of these bacterias necessitates careful collection and transport of patients specimens . In case of Fusospirochaetosis ( Fusotreponematose ) a specimen should be prepared for microscopic examination beside setting up a special culture . This is because the staining is the most suitable procedure for bacteril identification to support the clinical diagnosis of stomatitis ulceromembranacea ."
],
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]
}
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] |
[] |
[] |
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}
] |
HNO.70450007.eng.abstr
|
HNO.70450007.eng.abstr
|
[
{
"id": "HNO.70450007.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Few biochemical analyses on the mixed salivary kallikrein-prokallikrein system exist . At present , there is no statistically relevant information about possible relationships between mixed salivary kallikreins and malignant processes , especially oral squamous cell carcinoma ."
],
"offsets": [
[
0,
278
]
]
}
] |
[
{
"id": "HNO.70450007.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"analyses"
],
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[
16,
24
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0002778"
}
]
},
{
"id": "HNO.70450007.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"kallikrein-prokallikrein"
],
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[
47,
71
]
],
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"db_id": "C0022478"
}
]
},
{
"id": "HNO.70450007.eng.abstr-s1-t3",
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"kallikrein-prokallikrein"
],
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47,
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]
],
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"db_id": "C0033024"
}
]
},
{
"id": "HNO.70450007.eng.abstr-s2-t1",
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"kallikreins"
],
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[
199,
210
]
],
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"db_id": "C0022478"
}
]
},
{
"id": "HNO.70450007.eng.abstr-s2-t2",
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"text": [
"malignant"
],
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{
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"cell"
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]
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}
]
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{
"id": "HNO.70450007.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"carcinoma"
],
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267,
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]
],
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]
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{
"id": "HNO.70450007.eng.abstr-s2-t5",
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"squamous cell carcinoma"
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}
] |
[] |
[] |
[
{
"id": "HNO.70450007.eng.abstr-s1-r1-t3.1-t1.1",
"type": "interacts_with",
"arg1_id": "HNO.70450007.eng.abstr-s2-t3",
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},
{
"id": "HNO.70450007.eng.abstr-s1-r2-t1.1-t3.1",
"type": "analyzes",
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"arg2_id": "HNO.70450007.eng.abstr-s2-t3",
"normalized": []
},
{
"id": "HNO.70450007.eng.abstr-s1-r3-t1.1-t3.1",
"type": "measures",
"arg1_id": "HNO.70450007.eng.abstr-s2-t1",
"arg2_id": "HNO.70450007.eng.abstr-s2-t3",
"normalized": []
},
{
"id": "HNO.70450007.eng.abstr-s1-r4-t1.1-t3.1",
"type": "interacts_with",
"arg1_id": "HNO.70450007.eng.abstr-s2-t1",
"arg2_id": "HNO.70450007.eng.abstr-s2-t3",
"normalized": []
},
{
"id": "HNO.70450007.eng.abstr-s2-r1-t1.1-t4.1",
"type": "diagnoses",
"arg1_id": "HNO.70450007.eng.abstr-s2-t1",
"arg2_id": "HNO.70450007.eng.abstr-s2-t4",
"normalized": []
},
{
"id": "HNO.70450007.eng.abstr-s2-r2-t1.1-t2.1",
"type": "diagnoses",
"arg1_id": "HNO.70450007.eng.abstr-s2-t1",
"arg2_id": "HNO.70450007.eng.abstr-s2-t2",
"normalized": []
},
{
"id": "HNO.70450007.eng.abstr-s2-r3-t1.1-t2.1",
"type": "affects",
"arg1_id": "HNO.70450007.eng.abstr-s2-t1",
"arg2_id": "HNO.70450007.eng.abstr-s2-t2",
"normalized": []
},
{
"id": "HNO.70450007.eng.abstr-s2-r4-t2.1-t1.1",
"type": "produces",
"arg1_id": "HNO.70450007.eng.abstr-s2-t2",
"arg2_id": "HNO.70450007.eng.abstr-s2-t1",
"normalized": []
},
{
"id": "HNO.70450007.eng.abstr-s2-r5-t1.1-t5.1",
"type": "affects",
"arg1_id": "HNO.70450007.eng.abstr-s2-t1",
"arg2_id": "HNO.70450007.eng.abstr-s2-t5",
"normalized": []
},
{
"id": "HNO.70450007.eng.abstr-s2-r6-t1.1-t2.1",
"type": "disrupts",
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"arg2_id": "HNO.70450007.eng.abstr-s2-t2",
"normalized": []
},
{
"id": "HNO.70450007.eng.abstr-s2-r7-t2.1-t4.1",
"type": "location_of",
"arg1_id": "HNO.70450007.eng.abstr-s2-t2",
"arg2_id": "HNO.70450007.eng.abstr-s2-t4",
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},
{
"id": "HNO.70450007.eng.abstr-s2-r8-t1.1-t5.1",
"type": "diagnoses",
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"arg2_id": "HNO.70450007.eng.abstr-s2-t5",
"normalized": []
},
{
"id": "HNO.70450007.eng.abstr-s2-r9-t1.1-t4.1",
"type": "affects",
"arg1_id": "HNO.70450007.eng.abstr-s2-t1",
"arg2_id": "HNO.70450007.eng.abstr-s2-t4",
"normalized": []
},
{
"id": "HNO.70450007.eng.abstr-s2-r10-t2.1-t5.1",
"type": "location_of",
"arg1_id": "HNO.70450007.eng.abstr-s2-t2",
"arg2_id": "HNO.70450007.eng.abstr-s2-t5",
"normalized": []
}
] |
HNO.70450011.eng.abstr
|
HNO.70450011.eng.abstr
|
[
{
"id": "HNO.70450011.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The life span of HIV-infected patients has increased because of anti-retroviral therapy and improved means for treating opportunistic infections . However , HIV infection and subsequent immunosuppression result in an increased risk of high-grade B-cell lymphomas . The purpose of this study was to determine the incidence , localization , clinical features , therapy and survival time of patients with HIV-related lymphomas of the head and neck . Between 1988 and 1995 , 280 HIV-infected patients presented with otolaryngologic symptoms . Seventy-two ( 25.7% ) were found to have a neoplastic disease . Fifty-six of these patients ( 20% ) were diagnosed as having Kaposi's sarcoma and 12 ( 4.3% ) had lymphomas . According to the Kiel classification , lymphomas were subdivided into Hodgkin's disease ( 2 cases ) and B-cell lymphomas of high-grade malignancy ( 10 cases ) . These latter cases were centroblastic ( n=4), Burkitt's type ( n=4), anaplastic large cell ( n=1) and not classifiable ( n=1). All patients with HIV-related non-Hodgkin's lymphomas ( NHL ) were men and 8 were homosexuals . The mean age was 36.1 years . In addition to 7 nodal locations , high-grade B-cell lymphomas were found in the oropharynx ( n=2) and palate ( n=1). Four patients underwent chemotherapy , 1 patient underwent radiation therapy and 2 were treated with both methods . Two patients did not receive any treatment and 1 patient underwent laser therapy . The survival time depended on the previous diagnosis of AIDS , the patients ' immune status and the Karnofsky index . In 2 patients the lymphoma led to the diagnosis of HIV infection . Our findings show that any solitary or enlarging tumors or ulcerating lesions in the head and neck region of HIV patients must be examined histologically to exclude HIV-NHL . We also recommend that young patients with high-grade B-cell lymphomas should undergo HIV screening ."
],
"offsets": [
[
0,
1905
]
]
}
] |
[
{
"id": "HNO.70450011.eng.abstr-s1-t1",
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"life"
],
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4,
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]
],
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"db_id": "C0376558"
}
]
},
{
"id": "HNO.70450011.eng.abstr-s1-t2",
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"patients"
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]
],
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{
"id": "HNO.70450011.eng.abstr-s1-t3",
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"text": [
"anti-retroviral"
],
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]
],
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"db_id": "C0003209"
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}
]
},
{
"id": "HNO.70450011.eng.abstr-s1-t4",
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"therapy"
],
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]
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}
]
},
{
"id": "HNO.70450011.eng.abstr-s1-t5",
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"infections"
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}
]
},
{
"id": "HNO.70450011.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"opportunistic infections"
],
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120,
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]
],
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"db_id": "C0029118"
}
]
},
{
"id": "HNO.70450011.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"HIV"
],
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157,
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]
],
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"db_id": "C0019682"
}
]
},
{
"id": "HNO.70450011.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"infection"
],
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]
],
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}
]
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{
"id": "HNO.70450011.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"immunosuppression"
],
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}
]
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{
"id": "HNO.70450011.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"risk"
],
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]
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]
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{
"id": "HNO.70450011.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
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]
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{
"id": "HNO.70450011.eng.abstr-s2-t6",
"type": "umlsterm",
"text": [
"lymphomas"
],
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253,
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{
"id": "HNO.70450011.eng.abstr-s2-t7",
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{
"id": "HNO.70450011.eng.abstr-s2-t9",
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]
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"id": "HNO.70450011.eng.abstr-s3-t3",
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{
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{
"id": "HNO.70450011.eng.abstr-s3-t6",
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"lymphomas"
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"id": "HNO.70450011.eng.abstr-s3-t7",
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{
"id": "HNO.70450011.eng.abstr-s3-t8",
"type": "umlsterm",
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"neck"
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{
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]
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{
"id": "HNO.70450011.eng.abstr-s5-t1",
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{
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]
},
{
"id": "HNO.70450011.eng.abstr-s6-t2",
"type": "umlsterm",
"text": [
"sarcoma"
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},
{
"id": "HNO.70450011.eng.abstr-s6-t3",
"type": "umlsterm",
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"lymphomas"
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},
{
"id": "HNO.70450011.eng.abstr-s7-t1",
"type": "umlsterm",
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]
},
{
"id": "HNO.70450011.eng.abstr-s7-t2",
"type": "umlsterm",
"text": [
"lymphomas"
],
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]
},
{
"id": "HNO.70450011.eng.abstr-s7-t3",
"type": "umlsterm",
"text": [
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],
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{
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},
{
"id": "HNO.70450011.eng.abstr-s7-t6",
"type": "umlsterm",
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],
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]
},
{
"id": "HNO.70450011.eng.abstr-s7-t7",
"type": "umlsterm",
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{
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] |
[] |
[] |
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}
] |
HNO.70450017.eng.abstr
|
HNO.70450017.eng.abstr
|
[
{
"id": "HNO.70450017.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The rehabilitation of profoundly deaf patients by means of cochlear implants has become a well established form of therapy . Recently , large scale studies have pointed out a variety of surgical complications . A multiplicity of new implant types are each placing more specific demands on the surgeons . Based on the experience with about 160 cochlear implantations in total , the most suitable surgical technique for the implantation of the Combi 40 cochlear implant which has been used in 41 cases is presented . An extended retroauricular incision is made and a caudally based flap is fashioned . The implant bed is drilled 0.5-1 cm behind and above the mastoid cavity . Between the implant bed and the mastoid cavity a groove for the electrodes is drilled cranial of the implant site in the right ear and caudal in the left ear . Access to the scala tympani is gained by a promontory cochleostomy via a posterior tympanotomy of 2x3 mm . Videocontrolled microendoscopes are used to inspect the scala tympani prior to electrode insertion . Electrode insertions depths of up to 30 mm are usually achieved . The electrode and the implant are secured with ionomer-based cement . The described technique has up to now been successfully performed in 30 adults and 11 children ."
],
"offsets": [
[
0,
1274
]
]
}
] |
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},
{
"id": "HNO.70450017.eng.abstr-s12-t2",
"type": "umlsterm",
"text": [
"adults"
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{
"id": "HNO.70450017.eng.abstr-s12-t3",
"type": "umlsterm",
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"children"
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1264,
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{
"db_name": "UMLS",
"db_id": "C0008059"
}
]
}
] |
[] |
[] |
[
{
"id": "HNO.70450017.eng.abstr-s1-r1-t3.1-t5.2",
"type": "uses",
"arg1_id": "HNO.70450017.eng.abstr-s12-t3",
"arg2_id": "HNO.70450017.eng.abstr-s1-t5",
"normalized": []
},
{
"id": "HNO.70450017.eng.abstr-s1-r2-t3.1-t4.1",
"type": "performs",
"arg1_id": "HNO.70450017.eng.abstr-s12-t3",
"arg2_id": "HNO.70450017.eng.abstr-s7-t4",
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},
{
"id": "HNO.70450017.eng.abstr-s1-r3-t1.2-t4.1",
"type": "performs",
"arg1_id": "HNO.70450017.eng.abstr-s7-t1",
"arg2_id": "HNO.70450017.eng.abstr-s7-t4",
"normalized": []
},
{
"id": "HNO.70450017.eng.abstr-s1-r4-t3.1-t1.1",
"type": "performs",
"arg1_id": "HNO.70450017.eng.abstr-s12-t3",
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"normalized": []
},
{
"id": "HNO.70450017.eng.abstr-s1-r5-t1.2-t1.1",
"type": "performs",
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{
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{
"id": "HNO.70450017.eng.abstr-s2-r1-t1.1-t3.1",
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},
{
"id": "HNO.70450017.eng.abstr-s4-r1-t6.1-t2.1",
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},
{
"id": "HNO.70450017.eng.abstr-s4-r2-t6.1-t1.1",
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},
{
"id": "HNO.70450017.eng.abstr-s4-r3-t6.1-t6.2",
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},
{
"id": "HNO.70450017.eng.abstr-s4-r4-t5.1-t6.2",
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},
{
"id": "HNO.70450017.eng.abstr-s4-r5-t5.1-t2.1",
"type": "affects",
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},
{
"id": "HNO.70450017.eng.abstr-s4-r6-t5.1-t1.1",
"type": "affects",
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"normalized": []
},
{
"id": "HNO.70450017.eng.abstr-s6-r1-t1.1-t1.2",
"type": "causes",
"arg1_id": "HNO.70450017.eng.abstr-s12-t1",
"arg2_id": "HNO.70450017.eng.abstr-s7-t1",
"normalized": []
},
{
"id": "HNO.70450017.eng.abstr-s7-r1-t1.1-t1.2",
"type": "causes",
"arg1_id": "HNO.70450017.eng.abstr-s12-t1",
"arg2_id": "HNO.70450017.eng.abstr-s7-t1",
"normalized": []
},
{
"id": "HNO.70450017.eng.abstr-s7-r2-t6.1-t1.2",
"type": "location_of",
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"arg2_id": "HNO.70450017.eng.abstr-s7-t1",
"normalized": []
},
{
"id": "HNO.70450017.eng.abstr-s7-r3-t4.1-t1.2",
"type": "location_of",
"arg1_id": "HNO.70450017.eng.abstr-s7-t4",
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"normalized": []
},
{
"id": "HNO.70450017.eng.abstr-s7-r4-t3.1-t1.2",
"type": "causes",
"arg1_id": "HNO.70450017.eng.abstr-s12-t3",
"arg2_id": "HNO.70450017.eng.abstr-s7-t1",
"normalized": []
},
{
"id": "HNO.70450017.eng.abstr-s8-r1-t1.1-t2.1",
"type": "location_of",
"arg1_id": "HNO.70450017.eng.abstr-s12-t1",
"arg2_id": "HNO.70450017.eng.abstr-s12-t2",
"normalized": []
},
{
"id": "HNO.70450017.eng.abstr-s12-r1-t3.1-t1.1",
"type": "uses",
"arg1_id": "HNO.70450017.eng.abstr-s12-t3",
"arg2_id": "HNO.70450017.eng.abstr-s12-t1",
"normalized": []
}
] |
HNO.70450030.eng.abstr
|
HNO.70450030.eng.abstr
|
[
{
"id": "HNO.70450030.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Despite significant improvements in early detection of hearing losses in children , a relatively long interval still exists from initial concern by families to definite audiological identification . The aim of our retrospective cross-sectional study was to identify parental factors contributing to the delay of early detection . The parents of 70 hearing-impaired children were interviewed . All children were fitted with hearing aids in our clinical and had no additional physical or cognitive disabilities . At an average age of 19.5 months , parents or family doctors noticed first signs of a possible hearing impairment . On average it then took an additional 7.2 months until hearing impairment was diagnosed by an expert and the necessary first steps taken for rehabilitation ( fitting of hearing aids ) . Significantly , total hearing loss or profound hearing impairments were detected earlier than mild or moderate hearing impairments . In addition to hearing loss , parental education correlated significantly with an earlier start of rehabilitation . Statistical analysis revealed that children with hearing-impaired close relatives as well as first-born children tended to be diagnosed later . To further improve secondary prevention of hearing loss , the competence of specific parental groups should be taken into consideration ."
],
"offsets": [
[
0,
1343
]
]
}
] |
[
{
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"text": [
"hearing"
],
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[
55,
62
]
],
"normalized": [
{
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"db_id": "C0018767"
}
]
},
{
"id": "HNO.70450030.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"children"
],
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[
73,
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]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0008059"
}
]
},
{
"id": "HNO.70450030.eng.abstr-s1-t3",
"type": "umlsterm",
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[] |
[] |
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] |
HNO.70450036.eng.abstr
|
HNO.70450036.eng.abstr
|
[
{
"id": "HNO.70450036.eng.abstr-passage-0",
"type": "abstract",
"text": [
"It is known that gastroesophageal reflux disease is one of the causal agents for pathological changes in the larynx . The following case report reveals the relation between chronically habitual vomiting ( bulimia ) and alterations in the larynx , representing the findings typically seen in reflux laryngitis . The case describes the history of a 29-year old female patient who has suffered from bulimia for years and consequently developed a disorder of the singing-voice and an irritation of the throat . The medical history , laryngeal findings and the results obtained in the examination of the voice indicate the possible causative typical of gastroesophageal reflux disease are detected in patients with a matching history , corresponding age and gender , bulimia should be considered as one of the causes ."
],
"offsets": [
[
0,
813
]
]
}
] |
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{
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{
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},
{
"id": "HNO.70450036.eng.abstr-s2-t1",
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"vomiting"
],
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{
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298,
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{
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{
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{
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{
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},
{
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{
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{
"id": "HNO.70450036.eng.abstr-s3-t7",
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]
}
] |
[] |
[] |
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HNO.70450069.eng.abstr
|
HNO.70450069.eng.abstr
|
[
{
"id": "HNO.70450069.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The efficacy of intravenous lidocaine therapy in patients suffering form severe tinnitus aurium has been reported for many years although pharmacological mechanisms for its use are not fully understood . In order to evaluate the effectiveness of lidocaine therapy in the treatment of tinnitus we performed a retrospective study on 77 patients suffering from tinnitus who were treated between 1993 and 1995. All patients were given a test dose of lidocaine after a saline placebo infusion . Suppression of tinnitus was classified according to a visual analogue scale . Our results showed that 19 of the 77 patients investigated experienced different degrees of reduced tinnitus . Fourteen of these latter patients also were treated with oral tocainide 3x400 mg/day . Treatment was stopped in 13 of the patients because of side-effects or an insufficient effect on tinnitus . Our findings suggest that lidocaine and tocainide do not have a significant role in pharmacological treatment of tinnitus except in certain cases of long-standing severe tinnitus ."
],
"offsets": [
[
0,
1054
]
]
}
] |
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] |
[] |
[] |
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}
] |
HNO.70450074.eng.abstr
|
HNO.70450074.eng.abstr
|
[
{
"id": "HNO.70450074.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Surgical interventions in the petrous bone have to be performed in close relationship to vital and delicate anatomical structures . In cases of revision surgery or with massive pathological changes 3D computer-assisted navigation provides an essential tool for preoperative planning , definition of target structures and intraoperative orientation . This technology can help to diminish intraoperative risks for the patient and may help to optimize any microsurgery . In this report we present our first experiences in using the ISG Viewing Wand in the petrous bone through a specially designed model . By recording more than 4000 single measurements we found that the ISG Viewing Wand can be used with sufficient precision . We have now outlined the most important conditions necessary for possible application to a patient ."
],
"offsets": [
[
0,
826
]
]
}
] |
[
{
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],
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0,
8
]
],
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{
"id": "HNO.70450074.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"bone"
],
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[
38,
42
]
],
"normalized": [
{
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"db_id": "C0262950"
}
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{
"id": "HNO.70450074.eng.abstr-s1-t3",
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"anatomical"
],
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[
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118
]
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{
"id": "HNO.70450074.eng.abstr-s1-t4",
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HNO.70450081.eng.abstr
|
HNO.70450081.eng.abstr
|
[
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"id": "HNO.70450081.eng.abstr-passage-0",
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"A measurement system was developed that permits objective comparisons of the sound conduction of middle ear implants . The implants are fitted into a mechanical middle ear model which approximates the impedances of the eardrum and the inner ear . A defined signal within the frequency range of 0-5 kHz is provided by a miniaturized loudspeaker at the input to the model and is measured by a probe microphone . Displacement of an artificial stapes footplate at the output of the model is measured by a fiberoptic probe with a sensitivity of 5 nm . The transmission function is calculated as the quotient of the output and the input signal . This system can be used to evaluate the sound-transmitting properties of different middle ear implants excepting other influences , such as surgical techniques . This work details the measurement system and demonstrates basic influences on the sound-transmission of middle ear implants ."
],
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0,
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]
]
}
] |
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[] |
[] |
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] |
HNO.70450086.eng.abstr
|
HNO.70450086.eng.abstr
|
[
{
"id": "HNO.70450086.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Specific hearing aid selection and careful fitting are essential for successful rehabilitation of hearing-impaired children . For this reason the different hearing aid types prescribed , the type and frequency of hearing aid insufficiencies reported and the effectiveness and regularity of our followups were studied evaluating 253 followup exams in 39 children ( 71 ears ) suffering of a sensorineural hearing loss , including all degrees , supplied with a behind-the-ear hearing aid . Most of the devices had been prescribed outside our department on an initial trial basis . After critical evaluation , the number of hearing aid types was reduced from 33 to 23 when corresponding devices failed to match well with the degrees and types of hearing losses present . A further decrease in hearing aid types could not be achieved as a consequence of many being already end-prescribed . Insufficiencies ( n=222) were found in 60% of the hearing aid evaluations : 59% involved dynamic hearing aid adjustments requiring better amplification ( 37% ) , distorsion ( 18% ) and dynamics ( 4% ) . Additionally , 16% affected hearing aid function and another 16% form ( 9% ) and material ( 4% ) of the otoplasty and the tube ( 3% ) . The last 9% of the deficiencies concerned the potentiometer cap : it hadn ' t been fitted in about half of the cases and had been lost in the other half despite being needed . Routine followup evaluations of the hearing aids occurred regularly in 76% of the cases with an effectiveness of 73% . Our results confirm the importance and necessity for pedaudiologic qualitative hearing aid controls in children ."
],
"offsets": [
[
0,
1632
]
]
}
] |
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] |
HNO.70450091.eng.abstr
|
HNO.70450091.eng.abstr
|
[
{
"id": "HNO.70450091.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Warthin's tumour of the larynx is an unusual finding . In present literature only four cases have been reported . Only one case of a woman suffering from Warthin's tumour of the protid gland and the ipsilateral site of the larynx has been published . A case of a 74-year-old woman with an Warthin's tumour of the right parotid gland and the left false cord is presented . The theories about the development of Warthin's tumours are discussed ."
],
"offsets": [
[
0,
443
]
]
}
] |
[
{
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{
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"Warthin's"
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},
{
"id": "HNO.70450091.eng.abstr-s1-t3",
"type": "umlsterm",
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"tumour"
],
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10,
16
]
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}
]
},
{
"id": "HNO.70450091.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"larynx"
],
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[
24,
30
]
],
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]
},
{
"id": "HNO.70450091.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"finding"
],
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45,
52
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],
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},
{
"id": "HNO.70450091.eng.abstr-s2-t1",
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],
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},
{
"id": "HNO.70450091.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"woman"
],
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133,
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]
],
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},
{
"id": "HNO.70450091.eng.abstr-s3-t2",
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"Warthin's"
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{
"id": "HNO.70450091.eng.abstr-s3-t3",
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"Warthin's"
],
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154,
163
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],
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},
{
"id": "HNO.70450091.eng.abstr-s3-t4",
"type": "umlsterm",
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"tumour"
],
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[
164,
170
]
],
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}
]
},
{
"id": "HNO.70450091.eng.abstr-s3-t5",
"type": "umlsterm",
"text": [
"larynx"
],
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[
223,
229
]
],
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},
{
"id": "HNO.70450091.eng.abstr-s4-t1",
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},
{
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{
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{
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},
{
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},
{
"id": "HNO.70450091.eng.abstr-s4-t6",
"type": "umlsterm",
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],
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{
"id": "HNO.70450091.eng.abstr-s4-t7",
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{
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{
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{
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]
}
] |
[] |
[] |
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] |
HNO.70450117.eng.abstr
|
HNO.70450117.eng.abstr
|
[
{
"id": "HNO.70450117.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A safe closure of a dura lesion is necessary on account of the risk of potentially fatal ( late ) meningitis . 161 duraplasties of the frontal skull base carried out from 1979 to 1994 at the ENT-department Fulda were evaluated in a retrospective study in regard to etiology , operative techniques and results . Duraplasty of the rhinobasis was indicated in 70 cases of rhinobasal trauma , 47 cases after paranasal sinus surgery , 36 cases of tumors and 8 malformations . After an average follow-up time of 6 years the patients were interviewed for postoperative liquorrhea , sinusitis treated with antibiotics and meningitis . As an objective measure to verify the tight closure of the treated CSF-leaks a fluoreszein test was performed in 50,9 % 6 to 8 weeks after the operation . Duraplasty was successfull in more than 96 % . The approach and technique to perform a duraplasty have to be choosen individually considering size , location and etiology of the dural defect . In the majority of dural defects in the area of the frontal skull base reconstruction can be carried out now a days via an endonasal approach . By use of allogenic tissue , a mucosal flap from the surrounding area to cover the graft and fibrin clue good results were obtained ."
],
"offsets": [
[
0,
1252
]
]
}
] |
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}
] |
[] |
[] |
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},
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{
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{
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}
] |
HNO.70450128.eng.abstr
|
HNO.70450128.eng.abstr
|
[
{
"id": "HNO.70450128.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Despite significant progress in the therapy of craniofacial injuries permanent consequences of the trauma are still likely to occur . It has been possible to follow-up 105 ( 65,2% ) of the 161 patients who were treated for lateral and central midfacial fractures in our department between 1989 and 1991. Pathological findings on follow-up were found in 48,6% of our patients . Most frequent were persistent disturbances of the sensitivity in the area of the second branch of the trigeminal nerve ( 32,4% ) . Patients who were operated within the first week after trauma did have significantly less sensory disturbances than patients who underwent surgery later . 7,6% of our patients had permanent double vision ( 4,8% in their primary vision field ) . After subciliary incision 3% had an ectropium which was not found after transconjunctival incision . There was no significant difference in the cosmetic outcome of the two approaches . In one patient who received silicone for restoration of the orbital floor the plate did migrate . Other materials that were used for orbital floor reconstruction did not cause problems . Based on the post-operative results improvements for the therapeutic regimen are discussed ."
],
"offsets": [
[
0,
1217
]
]
}
] |
[
{
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],
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36,
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]
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}
]
},
{
"id": "HNO.70450128.eng.abstr-s1-t2",
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"text": [
"injuries"
],
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60,
68
]
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}
]
},
{
"id": "HNO.70450128.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"trauma"
],
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99,
105
]
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]
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{
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"patients"
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193,
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]
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]
},
{
"id": "HNO.70450128.eng.abstr-s2-t2",
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],
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253,
262
]
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}
]
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{
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317,
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}
]
},
{
"id": "HNO.70450128.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"sensitivity"
],
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[
427,
438
]
],
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{
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"db_id": "C0036667"
}
]
},
{
"id": "HNO.70450128.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"nerve"
],
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[
490,
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]
],
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}
]
},
{
"id": "HNO.70450128.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"trigeminal nerve"
],
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[
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]
],
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},
{
"id": "HNO.70450128.eng.abstr-s4-t1",
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"Patients"
],
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]
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}
]
},
{
"id": "HNO.70450128.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"trauma"
],
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}
]
},
{
"id": "HNO.70450128.eng.abstr-s4-t3",
"type": "umlsterm",
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]
},
{
"id": "HNO.70450128.eng.abstr-s4-t4",
"type": "umlsterm",
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}
]
},
{
"id": "HNO.70450128.eng.abstr-s4-t5",
"type": "umlsterm",
"text": [
"sensory disturbances"
],
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[
598,
618
]
],
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},
{
"id": "HNO.70450128.eng.abstr-s5-t1",
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]
},
{
"id": "HNO.70450128.eng.abstr-s5-t2",
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"vision"
],
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]
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]
},
{
"id": "HNO.70450128.eng.abstr-s5-t3",
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"vision"
],
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}
]
},
{
"id": "HNO.70450128.eng.abstr-s5-t4",
"type": "umlsterm",
"text": [
"double vision"
],
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]
],
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"db_id": "C0012569"
}
]
},
{
"id": "HNO.70450128.eng.abstr-s7-t1",
"type": "umlsterm",
"text": [
"cosmetic"
],
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"db_id": "C0010164"
}
]
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{
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"type": "umlsterm",
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"patient"
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]
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}
]
},
{
"id": "HNO.70450128.eng.abstr-s8-t2",
"type": "umlsterm",
"text": [
"silicone"
],
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[
966,
974
]
],
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},
{
"id": "HNO.70450128.eng.abstr-s8-t3",
"type": "umlsterm",
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"floor"
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}
]
},
{
"id": "HNO.70450128.eng.abstr-s8-t4",
"type": "umlsterm",
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"plate"
],
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[
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]
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}
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{
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"floor"
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}
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"cause"
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}
]
},
{
"id": "HNO.70450128.eng.abstr-s10-t1",
"type": "umlsterm",
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"therapeutic"
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[
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1193
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0039796"
}
]
}
] |
[] |
[] |
[
{
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},
{
"id": "HNO.70450128.eng.abstr-s1-r2-t1.1-t3.1",
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{
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},
{
"id": "HNO.70450128.eng.abstr-s2-r1-t2.1-t3.1",
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HNO.70450133.eng.abstr
|
HNO.70450133.eng.abstr
|
[
{
"id": "HNO.70450133.eng.abstr-passage-0",
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"Reliabel methods of reconstruction of the ossicular chain in the situation of an isolated arrosion of the long process of the incus using a tympanoplasty type II have not been available until recently . Instead , the tympanoplasty type III has been generally performed with the interposition of an autologous incus . In this presentation , we are describing two methods for reconstruction of the ossicular chain between the in-situ residing incus and the stapes on the other side so that the direct connection eventually will result in a tympanoplasty type II . In the first case , we used ionomeric cement in a way that features two characteristics : the direct connection between the stapes and the long process of the incus could be achieved as well as an articulation that was created on the head of the stapes . Hence , a too stiff connection between the head of the stapes and the long process of the incus could be avoided . In addition , a new method for precise microapplication of cooled bone cement ( IONOCAP LV ) with a syringe will be presented . In the second method titanium-gold-angle protheses have been crimped to the long process of the incus and positioned onto the head of the stapes in the way of an articulation . So far , comparison of the audiological results of those two methods of a tympanoplasty type II reveal in average better results than postoperative conductive hearing threshholds of the conventional tympanoplasty type III . If the achieved results can be reproduced on a larger number of patients , the expected audiological results are likely to resemble those of stapes surgery ."
],
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] |
[] |
[] |
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] |
HNO.70450140.eng.abstr
|
HNO.70450140.eng.abstr
|
[
{
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],
"offsets": [
[
0,
289
]
]
}
] |
[
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},
{
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{
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{
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},
{
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],
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127,
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]
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]
},
{
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],
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145,
154
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],
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},
{
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]
},
{
"id": "HNO.70450140.eng.abstr-s2-t4",
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],
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162,
169
]
],
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}
]
},
{
"id": "HNO.70450140.eng.abstr-s2-t5",
"type": "umlsterm",
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"hypoxic"
],
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[
183,
190
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0242184"
}
]
}
] |
[] |
[] |
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] |
HNO.70450205.eng.abstr
|
HNO.70450205.eng.abstr
|
[
{
"id": "HNO.70450205.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Central to inner ear research are questions regarding the homeostasis of the high endolymphatic potassium concentration ( ~150 mmol/l ) and the high endocochlear potential ( ~+80 mV ) . Disturbances of the endocochlear potential can lead to the immediate loss of hearing which may be irreversible . The molecular mechanism leading to the generation of the endocochlear potential has not yet been discovered in spite of its clinical relevance . It is long known , however , that the stria vascularis is responsible for both the generation of the endocochlear potential as well as the secretion of potassium into endolymph . Recent investigations have clarified the mechanisms leading to the secretion of potassium and have led to the formulation of a now widely accepted model . This model explaining potassium secretion as well as the generation of the endocochlear potential is discussed in the present article ."
],
"offsets": [
[
0,
913
]
]
}
] |
[
{
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{
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]
],
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}
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{
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],
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58,
69
]
],
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}
]
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{
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],
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96,
105
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{
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],
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119
]
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},
{
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],
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11,
20
]
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},
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],
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263,
270
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}
]
},
{
"id": "HNO.70450205.eng.abstr-s4-t2",
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"secretion"
],
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[
583,
592
]
],
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},
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]
},
{
"id": "HNO.70450205.eng.abstr-s4-t3",
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605
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},
{
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],
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611,
620
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],
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]
},
{
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],
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482,
498
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],
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},
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},
{
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},
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},
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],
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}
]
}
] |
[] |
[] |
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] |
HNO.70450210.eng.abstr
|
HNO.70450210.eng.abstr
|
[
{
"id": "HNO.70450210.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Several different theories exist about the orign of kinetosis and the space adaption syndrome , with individual sensitivities differing significantly . One explanation involves the hypothesis of a different otolith mass between the right and left statolith organ and especially a difference in the utricles . A difference in mass results in a different sensitivity to acceleration . For this reason we measured interindividual variances in saccular and utricular otolith mass . Since the anatomy of the vestibular organ in vertebrates is based as similar principles , we selected fish ( salmon and trout ) as our study model to facilitation preparations . The maximum difference in mass in the saccule was 17% and was generally smaller in the utricle , although in individual cases was much higher . We assume that a misbalanced sensitivity of the statolith organs occurs but is totally compensated for by the vestibular system as long as physiological motion patterns take place . Decompensation leads to kinetosis under non-physiological motion patterns . When the vestibular system is better balanced and has an equally distributed otolith mass to both sides , the possibility for developing kinetosis or space adaption syndrome is much less likely ."
],
"offsets": [
[
0,
1253
]
]
}
] |
[
{
"id": "HNO.70450210.eng.abstr-s1-t1",
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]
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"db_id": "C0007452"
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{
"id": "HNO.70450210.eng.abstr-s1-t2",
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"kinetosis"
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]
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{
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{
"id": "HNO.70450210.eng.abstr-s1-t4",
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"sensitivities"
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{
"id": "HNO.70450210.eng.abstr-s2-t1",
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"otolith"
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{
"id": "HNO.70450210.eng.abstr-s2-t2",
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"right"
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]
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}
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{
"id": "HNO.70450210.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"utricles"
],
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298,
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]
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{
"id": "HNO.70450210.eng.abstr-s3-t1",
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"sensitivity"
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{
"id": "HNO.70450210.eng.abstr-s3-t2",
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"acceleration"
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{
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{
"id": "HNO.70450210.eng.abstr-s5-t1",
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]
},
{
"id": "HNO.70450210.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"vertebrates"
],
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523,
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},
{
"id": "HNO.70450210.eng.abstr-s5-t3",
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"fish"
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{
"id": "HNO.70450210.eng.abstr-s5-t4",
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"salmon"
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{
"id": "HNO.70450210.eng.abstr-s5-t5",
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"trout"
],
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598,
603
]
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}
]
},
{
"id": "HNO.70450210.eng.abstr-s6-t1",
"type": "umlsterm",
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"saccule"
],
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[
694,
701
]
],
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]
},
{
"id": "HNO.70450210.eng.abstr-s6-t2",
"type": "umlsterm",
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"utricle"
],
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743,
750
]
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]
},
{
"id": "HNO.70450210.eng.abstr-s7-t1",
"type": "umlsterm",
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"sensitivity"
],
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829,
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]
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}
]
},
{
"id": "HNO.70450210.eng.abstr-s7-t2",
"type": "umlsterm",
"text": [
"motion"
],
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[
953,
959
]
],
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{
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"db_id": "C0026597"
}
]
},
{
"id": "HNO.70450210.eng.abstr-s8-t1",
"type": "umlsterm",
"text": [
"kinetosis"
],
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[
1006,
1015
]
],
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"db_id": "C0007452"
}
]
},
{
"id": "HNO.70450210.eng.abstr-s8-t2",
"type": "umlsterm",
"text": [
"kinetosis"
],
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[
1006,
1015
]
],
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}
]
},
{
"id": "HNO.70450210.eng.abstr-s8-t3",
"type": "umlsterm",
"text": [
"motion"
],
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[
1040,
1046
]
],
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{
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"db_id": "C0026597"
}
]
},
{
"id": "HNO.70450210.eng.abstr-s9-t1",
"type": "umlsterm",
"text": [
"otolith"
],
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[
1135,
1142
]
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"db_id": "C0029894"
}
]
},
{
"id": "HNO.70450210.eng.abstr-s9-t2",
"type": "umlsterm",
"text": [
"kinetosis"
],
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[
1195,
1204
]
],
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}
]
},
{
"id": "HNO.70450210.eng.abstr-s9-t3",
"type": "umlsterm",
"text": [
"kinetosis"
],
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[
1195,
1204
]
],
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}
]
},
{
"id": "HNO.70450210.eng.abstr-s9-t4",
"type": "umlsterm",
"text": [
"syndrome"
],
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[
1223,
1231
]
],
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{
"db_name": "UMLS",
"db_id": "C0039082"
}
]
}
] |
[] |
[] |
[
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"type": "part_of",
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"type": "affects",
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},
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"id": "HNO.70450210.eng.abstr-s5-r1-t1.1-t2.1",
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{
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{
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},
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},
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},
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},
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},
{
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},
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{
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{
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{
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},
{
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},
{
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},
{
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},
{
"id": "HNO.70450210.eng.abstr-s9-r3-t1.1-t3.1",
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"normalized": []
}
] |
HNO.70450216.eng.abstr
|
HNO.70450216.eng.abstr
|
[
{
"id": "HNO.70450216.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The overall aim of the present investigation was to develop a technique for endoscopic investigation of the cochlea . In the experiments reported here , the possible effect of the endoscope - called the \" cochleoscope \" - on the electrophysiology of the cochlea was investigated by recording the cochlear action potential ( CAP ) threshold tuning curve from ( 0.1-34 kHz ) . The dorsolateral bulla of anesthesized guinea pigs ( with ketamine 60 mg/kg and Rompun 12 mg/kg ) was opened , after which the cochleoscope was introduced under micromanipulator control through the round window membrane . Three cochleoscopes were used and had diameters of 0.29 mm , 0.7 mm and 0.89 mm , respectively , containing 2000 , 3000 and 3000 fibers each . Experiments in 7 animals showed that the cochleoscope did not influence CAP thresholds . Although the present resolution of the endoscopes is limited , the basilar membrane can be clearly distinguished from the osseous spiral lamina . It is anticipated that improved resolution will allow the cochleoscope to be used for diagnostic purposes in cases of sensorineural hearing loss ."
],
"offsets": [
[
0,
1121
]
]
}
] |
[
{
"id": "HNO.70450216.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"overall"
],
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[
4,
11
]
],
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{
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"db_id": "C0282416"
}
]
},
{
"id": "HNO.70450216.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"aim"
],
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[
12,
15
]
],
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{
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"db_id": "C0108800"
}
]
},
{
"id": "HNO.70450216.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"technique"
],
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[
62,
71
]
],
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{
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"db_id": "C0025664"
}
]
},
{
"id": "HNO.70450216.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"cochlea"
],
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[
108,
115
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0009195"
}
]
},
{
"id": "HNO.70450216.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"endoscope"
],
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[
180,
189
]
],
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{
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"db_id": "C0014243"
}
]
},
{
"id": "HNO.70450216.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"cochleoscope"
],
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[
205,
217
]
],
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"db_id": "C0211273"
}
]
},
{
"id": "HNO.70450216.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"cochleoscope"
],
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[
205,
217
]
],
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"db_id": "C0280558"
},
{
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"db_id": "C0068301"
},
{
"db_name": "UMLS",
"db_id": "C0009967"
}
]
},
{
"id": "HNO.70450216.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"electrophysiology"
],
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[
229,
246
]
],
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{
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"db_id": "C0013865"
}
]
},
{
"id": "HNO.70450216.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"cochlea"
],
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[
254,
261
]
],
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{
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"db_id": "C0009195"
}
]
},
{
"id": "HNO.70450216.eng.abstr-s2-t6",
"type": "umlsterm",
"text": [
"action potential"
],
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[
305,
321
]
],
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"db_id": "C0001272"
}
]
},
{
"id": "HNO.70450216.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"bulla"
],
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[
392,
397
]
],
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"db_id": "C0005758"
}
]
},
{
"id": "HNO.70450216.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"guinea"
],
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[
414,
420
]
],
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},
{
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"db_id": "C0018382"
}
]
},
{
"id": "HNO.70450216.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"pigs"
],
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[
421,
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]
],
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{
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"db_id": "C0039005"
}
]
},
{
"id": "HNO.70450216.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"ketamine"
],
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[
433,
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]
],
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"db_id": "C0022614"
}
]
},
{
"id": "HNO.70450216.eng.abstr-s3-t5",
"type": "umlsterm",
"text": [
"Rompun"
],
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[
455,
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"db_id": "C0043366"
}
]
},
{
"id": "HNO.70450216.eng.abstr-s3-t6",
"type": "umlsterm",
"text": [
"cochleoscope"
],
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[
502,
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]
],
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"db_id": "C0211273"
}
]
},
{
"id": "HNO.70450216.eng.abstr-s3-t7",
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] |
[] |
[] |
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"arg2_id": "HNO.70450216.eng.abstr-s7-t5",
"normalized": []
},
{
"id": "HNO.70450216.eng.abstr-s7-r31-t5.1-t1.1",
"type": "evaluation_of",
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"arg2_id": "HNO.70450216.eng.abstr-s7-t1",
"normalized": []
},
{
"id": "HNO.70450216.eng.abstr-s7-r32-t2.3-t1.1",
"type": "result_of",
"arg1_id": "HNO.70450216.eng.abstr-s7-t2",
"arg2_id": "HNO.70450216.eng.abstr-s7-t1",
"normalized": []
}
] |
HNO.70450222.eng.abstr
|
HNO.70450222.eng.abstr
|
[
{
"id": "HNO.70450222.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Ionomer-based cements are obtained by the reaction of an aluminum-fluoro-silicate glass with a polyalcenoic acid . During setting and hardening the cement bonds closely with adjacent hard tissue . The previous implantation of this material in the baboon tibia has held great promise as a possible use in bone replacement . In the present study the cement was tested concerning its biocompatibility and biostability in the middle ears of 64 rabbits . Viscid cement paste was inserted into the epitympanic space of each animal . A preformed cement strut was then placed to serve as a columella between the eardrum and stapes footplate . During a subsequent interval of 28 days up to 2 years middle ear specimens were evaluated under a surgical microscope , following which histologic sections were studied under light microscopic conditions . Findings demonstrated that after insertion of freshly mixed cement a firm adhesion to bone developed that proved to be biocompatible and biostable over time . After 28 days the preformed and fully hardened implants were overgrown by a delicate mucosa normally present in the middle ear . No evidence for any rejection of the implants could be found ."
],
"offsets": [
[
0,
1191
]
]
}
] |
[
{
"id": "HNO.70450222.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"glass"
],
"offsets": [
[
82,
87
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0017596"
},
{
"db_name": "UMLS",
"db_id": "C0015421"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"acid"
],
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[
108,
112
]
],
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{
"db_name": "UMLS",
"db_id": "C0001128"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"bonds"
],
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[
155,
160
]
],
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{
"db_name": "UMLS",
"db_id": "C0028758"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"hard"
],
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[
183,
187
]
],
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{
"db_name": "UMLS",
"db_id": "C0018599"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"tissue"
],
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[
188,
194
]
],
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{
"db_name": "UMLS",
"db_id": "C0040300"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"implantation"
],
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[
210,
222
]
],
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{
"db_name": "UMLS",
"db_id": "C0029976"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"baboon"
],
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[
247,
253
]
],
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"db_name": "UMLS",
"db_id": "C0030362"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"tibia"
],
"offsets": [
[
254,
259
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0040184"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"use"
],
"offsets": [
[
297,
300
]
],
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{
"db_name": "UMLS",
"db_id": "C0042153"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s3-t5",
"type": "umlsterm",
"text": [
"bone"
],
"offsets": [
[
304,
308
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0262950"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"ears"
],
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[
429,
433
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0013443"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"rabbits"
],
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[
440,
447
]
],
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"db_id": "C0034493"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"middle ears"
],
"offsets": [
[
422,
433
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0013455"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"paste"
],
"offsets": [
[
464,
469
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030634"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"animal"
],
"offsets": [
[
518,
524
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0003043"
},
{
"db_name": "UMLS",
"db_id": "C0003062"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s6-t1",
"type": "umlsterm",
"text": [
"eardrum"
],
"offsets": [
[
604,
611
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0041445"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s6-t2",
"type": "umlsterm",
"text": [
"stapes"
],
"offsets": [
[
616,
622
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0038152"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s7-t1",
"type": "umlsterm",
"text": [
"ear"
],
"offsets": [
[
696,
699
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0013443"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s7-t2",
"type": "umlsterm",
"text": [
"surgical"
],
"offsets": [
[
733,
741
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0038895"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s7-t3",
"type": "umlsterm",
"text": [
"histologic"
],
"offsets": [
[
771,
781
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0205462"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s7-t4",
"type": "umlsterm",
"text": [
"light"
],
"offsets": [
[
810,
815
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0023693"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s7-t5",
"type": "umlsterm",
"text": [
"middle ear"
],
"offsets": [
[
689,
699
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0013455"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s8-t1",
"type": "umlsterm",
"text": [
"Findings"
],
"offsets": [
[
841,
849
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0243095"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s8-t2",
"type": "umlsterm",
"text": [
"adhesion"
],
"offsets": [
[
915,
923
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0001511"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s8-t3",
"type": "umlsterm",
"text": [
"bone"
],
"offsets": [
[
927,
931
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0262950"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s8-t4",
"type": "umlsterm",
"text": [
"time"
],
"offsets": [
[
993,
997
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0040223"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s9-t1",
"type": "umlsterm",
"text": [
"mucosa"
],
"offsets": [
[
1085,
1091
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0026724"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s9-t2",
"type": "umlsterm",
"text": [
"ear"
],
"offsets": [
[
1123,
1126
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0013443"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s9-t3",
"type": "umlsterm",
"text": [
"middle ear"
],
"offsets": [
[
1116,
1126
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0013455"
}
]
},
{
"id": "HNO.70450222.eng.abstr-s10-t1",
"type": "umlsterm",
"text": [
"rejection"
],
"offsets": [
[
1149,
1158
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0035015"
}
]
}
] |
[] |
[] |
[
{
"id": "HNO.70450222.eng.abstr-s1-r1-t1.2-t1.1",
"type": "isa",
"arg1_id": "HNO.70450222.eng.abstr-s1-t1",
"arg2_id": "HNO.70450222.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s1-r2-t1.1-t2.1",
"type": "interacts_with",
"arg1_id": "HNO.70450222.eng.abstr-s10-t1",
"arg2_id": "HNO.70450222.eng.abstr-s9-t2",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s1-r3-t2.1-t1.1",
"type": "interacts_with",
"arg1_id": "HNO.70450222.eng.abstr-s9-t2",
"arg2_id": "HNO.70450222.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s2-r1-t2.1-t1.1",
"type": "result_of",
"arg1_id": "HNO.70450222.eng.abstr-s9-t2",
"arg2_id": "HNO.70450222.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s2-r2-t3.1-t1.1",
"type": "location_of",
"arg1_id": "HNO.70450222.eng.abstr-s9-t3",
"arg2_id": "HNO.70450222.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s3-r1-t1.1-t2.1",
"type": "affects",
"arg1_id": "HNO.70450222.eng.abstr-s10-t1",
"arg2_id": "HNO.70450222.eng.abstr-s9-t2",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s3-r2-t5.1-t1.1",
"type": "location_of",
"arg1_id": "HNO.70450222.eng.abstr-s7-t5",
"arg2_id": "HNO.70450222.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s3-r3-t5.1-t2.1",
"type": "part_of",
"arg1_id": "HNO.70450222.eng.abstr-s7-t5",
"arg2_id": "HNO.70450222.eng.abstr-s9-t2",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s3-r4-t3.1-t1.1",
"type": "location_of",
"arg1_id": "HNO.70450222.eng.abstr-s9-t3",
"arg2_id": "HNO.70450222.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s3-r5-t4.1-t1.1",
"type": "measurement_of",
"arg1_id": "HNO.70450222.eng.abstr-s8-t4",
"arg2_id": "HNO.70450222.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s3-r6-t3.1-t2.1",
"type": "part_of",
"arg1_id": "HNO.70450222.eng.abstr-s9-t3",
"arg2_id": "HNO.70450222.eng.abstr-s9-t2",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s4-r1-t1.1-t2.1",
"type": "part_of",
"arg1_id": "HNO.70450222.eng.abstr-s10-t1",
"arg2_id": "HNO.70450222.eng.abstr-s9-t2",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s4-r2-t1.1-t3.1",
"type": "interconnects",
"arg1_id": "HNO.70450222.eng.abstr-s10-t1",
"arg2_id": "HNO.70450222.eng.abstr-s9-t3",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s4-r3-t3.1-t1.1",
"type": "connected_to",
"arg1_id": "HNO.70450222.eng.abstr-s9-t3",
"arg2_id": "HNO.70450222.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s4-r4-t3.1-t2.1",
"type": "part_of",
"arg1_id": "HNO.70450222.eng.abstr-s9-t3",
"arg2_id": "HNO.70450222.eng.abstr-s9-t2",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s7-r1-t1.1-t5.1",
"type": "interconnects",
"arg1_id": "HNO.70450222.eng.abstr-s10-t1",
"arg2_id": "HNO.70450222.eng.abstr-s7-t5",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s7-r2-t5.1-t1.1",
"type": "connected_to",
"arg1_id": "HNO.70450222.eng.abstr-s7-t5",
"arg2_id": "HNO.70450222.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s8-r1-t3.1-t1.1",
"type": "location_of",
"arg1_id": "HNO.70450222.eng.abstr-s9-t3",
"arg2_id": "HNO.70450222.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s9-r1-t1.1-t2.1",
"type": "developmental_form_of",
"arg1_id": "HNO.70450222.eng.abstr-s10-t1",
"arg2_id": "HNO.70450222.eng.abstr-s9-t2",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s9-r2-t2.1-t1.1",
"type": "surrounds",
"arg1_id": "HNO.70450222.eng.abstr-s9-t2",
"arg2_id": "HNO.70450222.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s9-r3-t1.1-t3.1",
"type": "developmental_form_of",
"arg1_id": "HNO.70450222.eng.abstr-s10-t1",
"arg2_id": "HNO.70450222.eng.abstr-s9-t3",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s9-r4-t3.1-t2.1",
"type": "connected_to",
"arg1_id": "HNO.70450222.eng.abstr-s9-t3",
"arg2_id": "HNO.70450222.eng.abstr-s9-t2",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s9-r5-t3.1-t1.1",
"type": "surrounds",
"arg1_id": "HNO.70450222.eng.abstr-s9-t3",
"arg2_id": "HNO.70450222.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s9-r6-t2.1-t3.1",
"type": "interconnects",
"arg1_id": "HNO.70450222.eng.abstr-s9-t2",
"arg2_id": "HNO.70450222.eng.abstr-s9-t3",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s9-r7-t3.1-t1.1",
"type": "connected_to",
"arg1_id": "HNO.70450222.eng.abstr-s9-t3",
"arg2_id": "HNO.70450222.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "HNO.70450222.eng.abstr-s9-r8-t1.1-t3.1",
"type": "surrounds",
"arg1_id": "HNO.70450222.eng.abstr-s10-t1",
"arg2_id": "HNO.70450222.eng.abstr-s9-t3",
"normalized": []
}
] |
HNO.70450227.eng.abstr
|
HNO.70450227.eng.abstr
|
[
{
"id": "HNO.70450227.eng.abstr-passage-0",
"type": "abstract",
"text": [
"One of the major drawbacks using transient evoked otoacoustic emissions ( TEOAEs ) for hearing screening in newborn infants is the high fail rate in normal-hearing children . The purpose of the present study was to improve the overall performance of the test procedure and reduce of the fail rate . Improvement was obtained by 3 modifications : ( 1 ) change of the pass criterion in healthy newborns by requiring TEOAEs in at least one ear and nor both ears , ( 2 ) performing the test only after the second post-partum day , and ( 3 ) using a second-stage screening prior to hospital discharge in new-borns who failed the initial test . In all , 3980 newborns from 2 well-baby clinics and 243 new-borns from a neonatal intensive care unit ( NICU ) were screened using an system ILO-88 system program mode quick-check test was completed in 3820 infants . Considering these modifications , the pass rate of healthy new-borns was improved from 79.5% to > 99% , and only 0.7% of the false-negative ( healthy ) new-borns required further audiological evaluation . Babies from the NICU failed in 3.8% of the screening tests . Overall , the number of new-borns who failed the ILO-88 screening test was significantly reduced and the fail rate minimize when compared to previously published experiences with TEOAEs in new-born hearing screening ."
],
"offsets": [
[
0,
1338
]
]
}
] |
[
{
"id": "HNO.70450227.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"transient"
],
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[
33,
42
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0040704"
}
]
},
{
"id": "HNO.70450227.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"hearing"
],
"offsets": [
[
87,
94
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0018767"
}
]
},
{
"id": "HNO.70450227.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"screening"
],
"offsets": [
[
95,
104
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0220908"
},
{
"db_name": "UMLS",
"db_id": "C0220909"
}
]
},
{
"id": "HNO.70450227.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"newborn"
],
"offsets": [
[
108,
115
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0021289"
}
]
},
{
"id": "HNO.70450227.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"infants"
],
"offsets": [
[
116,
123
]
],
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] |
[] |
[] |
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},
{
"id": "HNO.70450227.eng.abstr-s7-r24-t2.1-t5.1",
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}
] |
HNO.70450367.eng.abstr
|
HNO.70450367.eng.abstr
|
[
{
"id": "HNO.70450367.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The development of modern endonasal sinus surgery is fundamentally based on the introduction of optical instrumentation . Endoscopes and microscopes are commonly used in such surgery . We tested a new combination of a stereoscopic single-channel endoscope with an operating microscope ( ENDO-OPMI ) for endonasal sinus surgery . This combination of the endoscope and microscope are connected in a way that results in a self-carried stereo-endoscope . To date , the ENDO-OPMI has been evaluated in cadaver studies and 7 cases of endonasal sinus surgery for chronic sinusitis . The trial was used to evaluate the clinical use of the current system and its possibilities for future developments ."
],
"offsets": [
[
0,
693
]
]
}
] |
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{
"id": "HNO.70450367.eng.abstr-s1-t1",
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"development"
],
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[
4,
15
]
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}
]
},
{
"id": "HNO.70450367.eng.abstr-s1-t2",
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"sinus"
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36,
41
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"surgery"
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42,
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{
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"instrumentation"
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104,
119
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{
"id": "HNO.70450367.eng.abstr-s2-t1",
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"Endoscopes"
],
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122,
132
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{
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"surgery"
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175,
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{
"id": "HNO.70450367.eng.abstr-s3-t1",
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"endoscope"
],
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246,
255
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},
{
"id": "HNO.70450367.eng.abstr-s3-t2",
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313,
318
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},
{
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"surgery"
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[
319,
326
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],
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},
{
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}
]
},
{
"id": "HNO.70450367.eng.abstr-s4-t1",
"type": "umlsterm",
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"endoscope"
],
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[
353,
362
]
],
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{
"db_name": "UMLS",
"db_id": "C0014243"
}
]
},
{
"id": "HNO.70450367.eng.abstr-s4-t2",
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"stereo-endoscope"
],
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432,
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"id": "HNO.70450367.eng.abstr-s5-t1",
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{
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"cadaver"
],
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[
497,
504
]
],
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}
]
},
{
"id": "HNO.70450367.eng.abstr-s5-t3",
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"sinus"
],
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[
538,
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]
],
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"db_name": "UMLS",
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}
]
},
{
"id": "HNO.70450367.eng.abstr-s5-t4",
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"surgery"
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544,
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}
]
},
{
"id": "HNO.70450367.eng.abstr-s5-t5",
"type": "umlsterm",
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"sinusitis"
],
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[
564,
573
]
],
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{
"db_name": "UMLS",
"db_id": "C0037199"
}
]
},
{
"id": "HNO.70450367.eng.abstr-s6-t1",
"type": "umlsterm",
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"use"
],
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[
620,
623
]
],
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{
"db_name": "UMLS",
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]
},
{
"id": "HNO.70450367.eng.abstr-s6-t2",
"type": "umlsterm",
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"future"
],
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[
672,
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],
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}
]
},
{
"id": "HNO.70450367.eng.abstr-s6-t3",
"type": "umlsterm",
"text": [
"developments"
],
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[
679,
691
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],
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{
"db_name": "UMLS",
"db_id": "C0243107"
},
{
"db_name": "UMLS",
"db_id": "C0020119"
}
]
}
] |
[] |
[] |
[
{
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"id": "HNO.70450367.eng.abstr-s1-r2-t4.1-t2.1",
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"id": "HNO.70450367.eng.abstr-s1-r5-t4.1-t1.1",
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},
{
"id": "HNO.70450367.eng.abstr-s1-r6-t2.1-t1.1",
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},
{
"id": "HNO.70450367.eng.abstr-s1-r7-t1.1-t3.1",
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},
{
"id": "HNO.70450367.eng.abstr-s1-r8-t2.1-t1.1",
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},
{
"id": "HNO.70450367.eng.abstr-s1-r9-t2.1-t3.1",
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},
{
"id": "HNO.70450367.eng.abstr-s2-r1-t1.1-t2.1",
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},
{
"id": "HNO.70450367.eng.abstr-s2-r2-t2.2-t2.1",
"type": "issue_in",
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"normalized": []
},
{
"id": "HNO.70450367.eng.abstr-s3-r2-t1.1-t3.1",
"type": "issue_in",
"arg1_id": "HNO.70450367.eng.abstr-s6-t1",
"arg2_id": "HNO.70450367.eng.abstr-s6-t3",
"normalized": []
},
{
"id": "HNO.70450367.eng.abstr-s3-r3-t2.1-t3.1",
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},
{
"id": "HNO.70450367.eng.abstr-s5-r1-t1.1-t4.1",
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},
{
"id": "HNO.70450367.eng.abstr-s5-r2-t3.1-t4.2",
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"normalized": []
},
{
"id": "HNO.70450367.eng.abstr-s5-r3-t4.2-t1.1",
"type": "affects",
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"normalized": []
},
{
"id": "HNO.70450367.eng.abstr-s5-r4-t3.1-t4.1",
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},
{
"id": "HNO.70450367.eng.abstr-s6-r1-t1.1-t3.1",
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},
{
"id": "HNO.70450367.eng.abstr-s6-r2-t3.1-t2.1",
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},
{
"id": "HNO.70450367.eng.abstr-s6-r3-t1.1-t3.1",
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},
{
"id": "HNO.70450367.eng.abstr-s6-r4-t1.1-t2.1",
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"normalized": []
}
] |
HNO.70450372.eng.abstr
|
HNO.70450372.eng.abstr
|
[
{
"id": "HNO.70450372.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Background : Intraoperative measurements of local intracapillary hemoglobin oxygenation of the human cochlea via the round window membrane have been shown to be possible using the Erlangen microlight-guided spectrophotometer . The aim of the present study was to develop a new microlight guide suitable for measurements in the round window niche and to evaluate electrophysiologically the possible impact of the procedure on the cochlea ."
],
"offsets": [
[
0,
438
]
]
}
] |
[
{
"id": "HNO.70450372.eng.abstr-s1-t1",
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"measurements"
],
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[
28,
40
]
],
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{
"db_name": "UMLS",
"db_id": "C0242485"
}
]
},
{
"id": "HNO.70450372.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"hemoglobin"
],
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65,
75
]
],
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{
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"db_id": "C0019046"
}
]
},
{
"id": "HNO.70450372.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"oxygenation"
],
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[
76,
87
]
],
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{
"db_name": "UMLS",
"db_id": "C0184633"
},
{
"db_name": "UMLS",
"db_id": "C0282636"
}
]
},
{
"id": "HNO.70450372.eng.abstr-s1-t4",
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"human"
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95,
100
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}
]
},
{
"id": "HNO.70450372.eng.abstr-s1-t5",
"type": "umlsterm",
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"cochlea"
],
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101,
108
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"db_id": "C0009195"
}
]
},
{
"id": "HNO.70450372.eng.abstr-s1-t6",
"type": "umlsterm",
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"membrane"
],
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[
130,
138
]
],
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"db_id": "C0025255"
}
]
},
{
"id": "HNO.70450372.eng.abstr-s1-t7",
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"round window"
],
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117,
129
]
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{
"id": "HNO.70450372.eng.abstr-s2-t1",
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]
},
{
"id": "HNO.70450372.eng.abstr-s2-t2",
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"microlight"
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277,
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]
},
{
"id": "HNO.70450372.eng.abstr-s2-t3",
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"measurements"
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307,
319
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},
{
"id": "HNO.70450372.eng.abstr-s2-t4",
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{
"id": "HNO.70450372.eng.abstr-s2-t5",
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},
{
"id": "HNO.70450372.eng.abstr-s2-t6",
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[
327,
339
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],
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{
"db_name": "UMLS",
"db_id": "C0035878"
}
]
}
] |
[] |
[] |
[
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] |
HNO.70450378.eng.abstr
|
HNO.70450378.eng.abstr
|
[
{
"id": "HNO.70450378.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Distortion product otoacoustic emissions ( DPOAEs ) are probably based on the motile properties of the cochlear outer hair cells ( OHCs ) , which are richly innervated by medial olivo-cochlear efferent nerves ( MOCs ) . DPOAEs provide a stimulating model for functional exploration of the efferent system . The influences of contralateral acoustic stimulation were studied on the amplitude of ipsilateral DPOAEs at the frequency 2f1-f2. Fifteen ears of adults with normal hearing ( 7 women , 8 men , mean age ; 23.1 +/- 4.2 years ) were examined . Sound stimulation consisted of exposure to 6 successive series of contralateral pure tones at frequencies between 0.5 and 4.0 kHz and low intensities of 30 dB HL . DP grams were registered with f2 ranging from 708 to 6165 Hz. Contralateral pure tones in the frequency range above 750 Hz and with intensities of 30 dB HL increased the ipsilaterally registered DPOAE amplitudes . The results showed that this increase was frequency specific , at least for frequencies at 1 and 2 kHz . The frequency specificity was especially marked when ipsilateral f2 was near 1 kHz . Contralateral frequencies of 3 and 4 kHz induced a significant , increasing effect , including ipsilateral frequencies around f2=3 kHz ( or 4 kHz ) and also lower frequencies around f2=1 kHz . Our results support the concept that the observed increase in DPOAE amplitudes is mediated by the medial olivo-cochlear efferent system . The rule of OHCs as a cochlear amplifier in the presence of contralateral low-intensity sound stimulation is discussed ."
],
"offsets": [
[
0,
1567
]
]
}
] |
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{
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] |
[] |
[] |
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HNO.70450385.eng.abstr
|
HNO.70450385.eng.abstr
|
[
{
"id": "HNO.70450385.eng.abstr-passage-0",
"type": "abstract",
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"Testing gaze movements is very important for the detection of central vestibular diseases . The intent of this study was to clarify the pathological importance of partially disturbed and completely disturbed smooth pursuit movements . One hundred patients were analyzed and curves of smooth pursuit movements were classified into three groups of different deformations : i . e , regular , partially disturbed and completely disturbed movements . The correlation index of each curve was then calculated . In 16 patients qualitative analysis showed a completely disturbed result in the smooth pursuit test . Nine of the patients ( 56.3% ) showed morphological signs of a central disease . Twenty-nine patients yielded a partially disturbed test result and in 2 of them ( 6.9% ) a central pathological illness was uncovered . Patients with completely disturbed smooth pursuits showed the highest average binocular correlation index ( 1.44 ) . Others with partially disturbed results gave an index of 1.24 , while persons with regular smooth pursuits yielded a value of 1.17. Because of the scattering seen , it was not definitely possible to attach a correlation index to central disease . On the other hand , an index higher than 1.3 should arouse suspicion for a central illness . Only completely disturbed smooth pursuit movements frequently appear in connection with central diseases . As a rule , a partially disturbed result does not indicate diseases of the central nervous system ."
],
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}
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[] |
[] |
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HNO.70450433.eng.abstr
|
HNO.70450433.eng.abstr
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{
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],
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0,
131
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]
}
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[] |
[] |
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HNO.70450442.eng.abstr
|
HNO.70450442.eng.abstr
|
[
{
"id": "HNO.70450442.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Animal experiments with microbiologic examinations and studies in cell cultures have shown that ionomer cement is a biocompatible and biostable bone replacement material in the head and neck region . Clinical and functional results of its use in the human middle ear have proven to be satisfactory during a maximal period of 2.5 years observation . The present trial was continued in order to determine the long-term behavior of ionomer cement ( Ionos partial and total ossicles ) after reconstruction of the ossicular chain . The ossicular chain was reconstructed in 343 cases and included various losses of one or more of the ossicles ( i.e. , incus , incus and malleus , incus and stapes superstructure , and malleus , incus and stapes superstructure ) . Follow-up extended over a maximum period of 5.5 years . Patients were examined under a surgical microscope and a pure-tone audiogram was performed at regular intervals ."
],
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[
0,
927
]
]
}
] |
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] |
[] |
[] |
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] |
HNO.70450448.eng.abstr
|
HNO.70450448.eng.abstr
|
[
{
"id": "HNO.70450448.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A retrospective study over 5 years evaluated the medical records of 78 patients who had suffered lateral skull base fractures . The purpose of the present study was to answer the question of whether antibiotic prophylaxis reduced the risk of meningitis . Fifty-five of 78 patients ( 71% ) were given no antibiotics , among whom four developed meningitis . In 29% of patients treated with antibiotics , two developed meningitis . This difference was not significant . Even when cases with uncomplicated ( \" simple \" ) lateral skull base fractures were separated from those with severe additional lesions related to their injuries , no significant correlation was found in the occurrence of meningitis despite the use of an antibiotic . Eight of 14 patients with initial otoliquorrheas were treated with antibiotics , with two of these 8 patients developing meningitis . None of the patients who did not receive antibiotics developed meningitis . Our findings show that it is not advisible to treat patients who have suffered from lateral skull base fractures with prophylactic antibiotics . Instead , these patients should be examined frequently and appropriate antibiotic therapy prescribed at the first clinical symptoms of meningitis ."
],
"offsets": [
[
0,
1237
]
]
}
] |
[
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15
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{
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{
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{
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[] |
[] |
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HNO.70450453.eng.abstr
|
HNO.70450453.eng.abstr
|
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"Replacement of the tracheal conduit remains an unresolved problem . The microporous material expanded polytetrafluorethylene ( ePTFE ) is suitable for tracheal reconstruction . The aim of our study was to improve the limited mechanical properties of this material by incorporating reinforcement elements and to examine the influence of these elements on host incorporation and epithelialization . In so dours ePTFE prostheses were reinforced with Ionomer cement and porous high density polyethylene ( pHDPE ) rings and implanted into the neck muscle of miniature pigs . One of these prostheses was epithelialized by a cell seeding technique and was thus placed into a tracheal defect . Results were examined grossly by endoscopy and than by light and scanning electron microscopy . The shapes of both types of prostheses showed a high stability . The reinforcement elements did not impair bioincorporation or the ability to epithelialize . In vivo interposition of an incorporated and epithelialized prosthesis to a host led to cell differentiation . The improved biomechanical properties of the prostheses waid and the reproducible formation of epitheliums are important advances in the solution of effectively correcting tracheal defects ."
],
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]
}
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HNO.70450512.eng.abstr
|
HNO.70450512.eng.abstr
|
[
{
"id": "HNO.70450512.eng.abstr-passage-0",
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],
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[
0,
518
]
]
}
] |
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HNO.70450523.eng.abstr
|
HNO.70450523.eng.abstr
|
[
{
"id": "HNO.70450523.eng.abstr-passage-0",
"type": "abstract",
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"The available literature on psychosocial aspects of head and neck cancer surgery from 1950 to 1995 was reviewed in four parts . Part 3 is a detailed description of the findings looked at from four different points of view : ..."
],
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[
0,
227
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}
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] |
[] |
[] |
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{
"id": "HNO.70450523.eng.abstr-s1-r13-t5.2-t6.1",
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}
] |
HNO.70450533.eng.abstr
|
HNO.70450533.eng.abstr
|
[
{
"id": "HNO.70450533.eng.abstr-passage-0",
"type": "abstract",
"text": [
"This report summarizes our experiences with the subjective visual vertical ( SVV ) as a clinical neuro-otological tool . In the SVV test , patients have to orient a dim light bar in an otherwise dark surrounding earth-vertical , using a remote-control . Normal subjects in an upright position did not deviate more than 2 ° from true vertical . After vestibular neurectomy , the SVV was consistently tilted by some 12 ° toward the affected ear . Smaller tilts ( ~7 ° ) of the SVV occured in patients with spontaneous peripheral vestibular diseases . This shift in SVV disappeared within weeks to months , similar to the spontaneous nystagmus . After stapes surgery slight deviations of the SVV towards the unoperated ear were seen in about 20% of the patients , indicating a slight irritation of the otolith organs . Assessed in an upright position , the SVV thus may be regarded as reflecting tonic otolithic input differences between the two ears ."
],
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[
0,
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]
}
] |
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{
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{
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{
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{
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{
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{
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649,
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{
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"db_id": "C0013443"
}
]
}
] |
[] |
[] |
[
{
"id": "HNO.70450533.eng.abstr-s2-r1-t1.1-t3.1",
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{
"id": "HNO.70450533.eng.abstr-s7-r3-t5.1-t2.1",
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},
{
"id": "HNO.70450533.eng.abstr-s7-r4-t4.1-t5.1",
"type": "performs",
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{
"id": "HNO.70450533.eng.abstr-s7-r5-t4.1-t2.1",
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"normalized": []
}
] |
HNO.70450538.eng.abstr
|
HNO.70450538.eng.abstr
|
[
{
"id": "HNO.70450538.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The dynamic behavior of the ossicular chain is very complex and is frequency-dependent . To date , this has still not been fully investigated or understood . There remains a lack of measurement procedures to pick up the motion of the ossicles and ear drum simultaneously with sufficient resolution . The presented paper reports simultanous measurements with laser-Doppler vibrometry at two points of the ossicular chain of cadaver specimens . Motions not observed were derived using mechanical simulation models on a computer and then evaluating appropriate mathematical equations . Using a sound stimulus , the displacement velocities of the umbo and stapes footplate were measured , and the corresponding transfer functions were derived by Fourier transform . Results were used for verification of the computer models . In the current investigations these models were refined and allow for the detailed investigation of the dynamic behavior of the ossicular chain , facilitating the optimal design of passive and active middle-ear implants ."
],
"offsets": [
[
0,
1043
]
]
}
] |
[
{
"id": "HNO.70450538.eng.abstr-s1-t1",
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"behavior"
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[
12,
20
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"db_id": "C0004927"
}
]
},
{
"id": "HNO.70450538.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"frequency-dependent"
],
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[
67,
86
]
],
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{
"db_name": "UMLS",
"db_id": "C0376249"
}
]
},
{
"id": "HNO.70450538.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"date"
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[
92,
96
]
],
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"db_id": "C0011008"
}
]
},
{
"id": "HNO.70450538.eng.abstr-s3-t1",
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"measurement"
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182,
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]
},
{
"id": "HNO.70450538.eng.abstr-s3-t2",
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"text": [
"procedures"
],
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[
194,
204
]
],
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"db_id": "C0184661"
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]
},
{
"id": "HNO.70450538.eng.abstr-s3-t3",
"type": "umlsterm",
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"motion"
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220,
226
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{
"id": "HNO.70450538.eng.abstr-s3-t4",
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},
{
"id": "HNO.70450538.eng.abstr-s3-t5",
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"text": [
"ear drum"
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247,
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{
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{
"id": "HNO.70450538.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"Motions"
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"id": "HNO.70450538.eng.abstr-s5-t2",
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] |
[] |
[] |
[
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}
] |
HNO.70450545.eng.abstr
|
HNO.70450545.eng.abstr
|
[
{
"id": "HNO.70450545.eng.abstr-passage-0",
"type": "abstract",
"text": [
"For the evaluation of neoplastic orbital lesions an interdisciplinary concept is crucial and includes modern imaging techniques as well as rhinosurgical approaches to the orbit . During a 14-year period 6 primary malignant orbital lymphomas and 9 cases of orbital pseudotumors were managed at our department . In most of the cases an exophthalmus with painful swelling of the eyelids , diplopia and a loss of vision were the clinical symptoms . Imaging using CT or MRI revealed homogeneous tissue formations that could not be clearly demarcated from adjacent orbital structures . By a rhinosurgical approach a biopsy was performed of each lesion without surgical complications . Following diagnosis the localized malignant lymphomas of the orbit were irradiated . In one patient systemic spread of tumor required multi-drug chemotherapy . Two patients died as the result of the sequleae of disseminated plasmocytomas . Patients with orbital pseudotumors were treated with systemic steroids . Two patients were also irradiated . No malignant transformation of any orbital pseudotumor was observed in this series . Our experiences show that careful histological evaluation of lymphoid orbital masses is necessary for correct diagnosis , especially since this has great impact on treatment and prognosis . Depending on the localization of a lesion medial orbitotomy by a rhinosurgical approach has proven to be a safe method for performing a biopsy or extirpating tumor ."
],
"offsets": [
[
0,
1468
]
]
}
] |
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[] |
[] |
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},
{
"id": "HNO.70450545.eng.abstr-s13-r23-t2.1-t1.1",
"type": "interacts_with",
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"arg2_id": "HNO.70450545.eng.abstr-s13-t1",
"normalized": []
}
] |
HNO.70450556.eng.abstr
|
HNO.70450556.eng.abstr
|
[
{
"id": "HNO.70450556.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Diseases of the oral cavity , floor of the mouth , and nervous system can be accompanied by disturbances in tongue movement during swallowing . These disturbances can be diagnosed by videosonography whereby the examiner has to evaluate extensive video documentation of lingual motion . It was the aim of this study to facilitate this evaluation by the application of a reproducible computer-assisted quantitative analysis procedure . Video sequences of 56 healthy adults and 19 patients with dysphagias of different etiologies were analysed . A numerical estimation of swallowing movements was carried out in abstraction from the structures imaged ( bolus , air , muscles of the tongue , floor of the mouth , hyoid , etc. ) . Intensity changes of the pixels within previously defined radial image sectors were quantified in relationship to time and depicted as sector curves . The healthy adults demonstrated a characteristic pattern of two motion maxima that appeared within almost all sector curves . These maxima represented bolus transport movements and the reset movement of the tongue . Patients with diseases of the tongue or neuromuscular changes caused by disturbances of the central nervous system showed pathological deviations on videosonography . These appeared as local or general reductions in movement , slow speed motions , repetitive swallowing or unsorted additional movements of the tongue during swallowing ."
],
"offsets": [
[
0,
1429
]
]
}
] |
[
{
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8
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}
]
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{
"id": "HNO.70450556.eng.abstr-s1-t2",
"type": "umlsterm",
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"floor"
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}
]
},
{
"id": "HNO.70450556.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"mouth"
],
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43,
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]
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]
},
{
"id": "HNO.70450556.eng.abstr-s1-t4",
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"nervous"
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}
]
},
{
"id": "HNO.70450556.eng.abstr-s1-t5",
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"tongue"
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}
]
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{
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"movement"
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{
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"oral cavity"
],
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27
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{
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55,
69
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]
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{
"id": "HNO.70450556.eng.abstr-s2-t1",
"type": "umlsterm",
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"documentation"
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]
},
{
"id": "HNO.70450556.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"motion"
],
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{
"id": "HNO.70450556.eng.abstr-s3-t1",
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"aim"
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{
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"evaluation"
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"analysis"
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{
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"procedure"
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{
"id": "HNO.70450556.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"adults"
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{
"id": "HNO.70450556.eng.abstr-s4-t2",
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},
{
"id": "HNO.70450556.eng.abstr-s4-t3",
"type": "umlsterm",
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"dysphagias"
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},
{
"id": "HNO.70450556.eng.abstr-s4-t4",
"type": "umlsterm",
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"etiologies"
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]
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{
"id": "HNO.70450556.eng.abstr-s5-t1",
"type": "umlsterm",
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{
"id": "HNO.70450556.eng.abstr-s5-t2",
"type": "umlsterm",
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"air"
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},
{
"id": "HNO.70450556.eng.abstr-s5-t3",
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"muscles"
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]
},
{
"id": "HNO.70450556.eng.abstr-s5-t4",
"type": "umlsterm",
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"tongue"
],
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},
{
"id": "HNO.70450556.eng.abstr-s5-t5",
"type": "umlsterm",
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{
"id": "HNO.70450556.eng.abstr-s5-t6",
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"mouth"
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]
},
{
"id": "HNO.70450556.eng.abstr-s5-t7",
"type": "umlsterm",
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"hyoid"
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{
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{
"id": "HNO.70450556.eng.abstr-s7-t1",
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"adults"
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{
"id": "HNO.70450556.eng.abstr-s7-t2",
"type": "umlsterm",
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"motion"
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},
{
"id": "HNO.70450556.eng.abstr-s8-t1",
"type": "umlsterm",
"text": [
"transport"
],
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]
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},
{
"id": "HNO.70450556.eng.abstr-s8-t2",
"type": "umlsterm",
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"movements"
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},
{
"id": "HNO.70450556.eng.abstr-s8-t3",
"type": "umlsterm",
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{
"id": "HNO.70450556.eng.abstr-s8-t4",
"type": "umlsterm",
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"tongue"
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}
]
},
{
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"type": "umlsterm",
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]
},
{
"id": "HNO.70450556.eng.abstr-s9-t2",
"type": "umlsterm",
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"diseases"
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{
"id": "HNO.70450556.eng.abstr-s9-t3",
"type": "umlsterm",
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"tongue"
],
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]
},
{
"id": "HNO.70450556.eng.abstr-s9-t4",
"type": "umlsterm",
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},
{
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{
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},
{
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},
{
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"motions"
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},
{
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{
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},
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"db_id": "C0040408"
}
]
}
] |
[] |
[] |
[
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{
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HNO.70450563.eng.abstr
|
HNO.70450563.eng.abstr
|
[
{
"id": "HNO.70450563.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The case of a 24-year-old woman with a plunging ranula is reported . Primarily , the patient noticed extensive swelling of the neck , which had developed 3 months previously . The polycystic , firmly attached tumor and the sublingual and submandibular glands of the right side of the neck were surgically removed . Pathological examination showed a retention cyst by means of a plunging ranula . The etiology , pathogenesis , clinical aspect and diagnostic procedures for the plunging ranula are described . Various therapeutic possibilities are discussed in regard to their value . We prefer surgical treatment with a histological examination to verify the diagnosis . The plunging ranula originates on the sublingual gland ; therefore , its simultaneous extirpation is recommended to avoid recurrences . In extensive cases , the additional removal of the submandibular gland can be advised ."
],
"offsets": [
[
0,
893
]
]
}
] |
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]
}
] |
[] |
[] |
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] |
HNO.70450567.eng.abstr
|
HNO.70450567.eng.abstr
|
[
{
"id": "HNO.70450567.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Bilophila wadsworthia is an obligately anaerobic , gram-negative rod , which was first described in 1989. The natural habitat of this species seems to be the lower intestinal tract where it was recovered from about 60% of the persons investigated . Bilophila wadsworthia is mainly associated with intra-abdominal infections , but the species was also isolated as part of aerobic-anaerobic mixed infections at various extra-abdominal sites . Otological infections due to Bilophila wadsworthia have as yet not been described . In the present paper , we report a case of a patient with postoperative otitis externa following stapedectomy , probably caused by the anaerobes Becteroides fragilis and Bilophila wadsworthia ."
],
"offsets": [
[
0,
718
]
]
}
] |
[
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{
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{
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{
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},
{
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{
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},
{
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},
{
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611
]
],
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"db_id": "C0029878"
}
]
}
] |
[] |
[] |
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HNO.70450610.eng.abstr
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HNO.70450610.eng.abstr
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0,
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[] |
[] |
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HNO.70450618.eng.abstr
|
HNO.70450618.eng.abstr
|
[
{
"id": "HNO.70450618.eng.abstr-passage-0",
"type": "abstract",
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"In a monocenter prospective randomized double-blind clinical trial the efficacy of homeopathic treatment was investigated on children with adenoid vegetations justifying an operation . Patients were treated with either homeopathic remedies such as Nux vomica D200, Okoubaka D3, Tuberculinum D200, Barium jodatum D4 and Barium jodatum D6 or with placebo . The duration of the study for each patient was 3 months . Examination of the ears using a microscope , rhinoscopy , stomatoscopy and pharyngoscopy , as well as tympanometry and audiometry were performed after 4 , 8 and 12 weeks . Out of a total of 97 children studied between the ages of 4 to 10 years 82 could be analyzed . At the end of the study no operation was required in 70.7% of the placebo-treated children and in 78.1% of the children treated with homeopathic preparations . These results show no statistical significance ."
],
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888
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{
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{
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"children"
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}
] |
[] |
[] |
[
{
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},
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},
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},
{
"id": "HNO.70450618.eng.abstr-s1-r6-t4.1-t5.1",
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},
{
"id": "HNO.70450618.eng.abstr-s1-r7-t4.1-t1.1",
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},
{
"id": "HNO.70450618.eng.abstr-s1-r8-t1.1-t5.2",
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},
{
"id": "HNO.70450618.eng.abstr-s1-r9-t4.1-t2.1",
"type": "location_of",
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"normalized": []
},
{
"id": "HNO.70450618.eng.abstr-s2-r1-t5.1-t2.1",
"type": "interacts_with",
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},
{
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},
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},
{
"id": "HNO.70450618.eng.abstr-s2-r4-t1.1-t4.1",
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},
{
"id": "HNO.70450618.eng.abstr-s2-r5-t5.1-t3.1",
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{
"id": "HNO.70450618.eng.abstr-s4-r1-t1.1-t2.1",
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{
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},
{
"id": "HNO.70450618.eng.abstr-s5-r2-t2.2-t1.1",
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},
{
"id": "HNO.70450618.eng.abstr-s6-r1-t3.1-t1.1",
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"arg2_id": "HNO.70450618.eng.abstr-s6-t1",
"normalized": []
}
] |
HNO.70450625.eng.abstr
|
HNO.70450625.eng.abstr
|
[
{
"id": "HNO.70450625.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Laser treatment of various skin changes has become common clinical practice in recent years . Due to its physical properties , the CO2 laser is particularly well suited for cutting and ablating tissue . The high absorption of its wavelength in water ( =10600 nm ) is responsible for its low penetration depth in biological tissue . Shortening the exposure time minimizes thermal side effects , such as carbonization and coagulation . This effect can be lessened with the SilkTouch scanner , since the focussed laser beam is moved over a defined area by rapidly rotating mirrors . This enables a controlled and reliable removal of various dermal lesions . Particularly well-suited for treatment hypertrophic scars , post-acne scarring , perioral and periorbital wrinkles , rhinophymas and benign neoplasms including verruca vulgaris . Cosmetically favorable reepithelialization of the treated skin surfaces occurs within a very short time after treatment . Periorbital resurfacing and correction of a rhinophyma are used as examples of dermal treatment with the CO2 laser and the SilkTouch scanner ."
],
"offsets": [
[
0,
1098
]
]
}
] |
[
{
"id": "HNO.70450625.eng.abstr-s1-t1",
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"Laser"
],
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[
0,
5
]
],
"normalized": [
{
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"db_id": "C0023089"
}
]
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] |
[] |
[] |
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HNO.70450630.eng.abstr
|
HNO.70450630.eng.abstr
|
[
{
"id": "HNO.70450630.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The development of a middle ear cholesteatoma is usually associated with chronic inflammation and displacement of the mucosa present by the invading squamous epithelium . To analyze the clinically different behaviors of both epithelia , we used immunohistochemical methods to study the distribution and expression of interleukin-1 ( Il-1), transforming growth factor-alpha ( TGF- ) , epidermal growth factor ( EGF ) , epidermal growth factor-receptor ( EGF-R ) , the proliferation marker MIB 1 , c-myc proto-oncogene product and activation marker 4F2. Results stromal that keratinocytes in a cholesteatoma exhibited a much higher activation and proliferation rate when compared to middle ear mucosa cells . Middle ear epithelial cells showed no immunoreactivity for TGF-alpha , EGF-R , Il-1 and c-myc in contrast to the markedly positive immunoreactivity found in cholesteatoma matrix . The local release of cytokines and growth factors , such as TGF-alpha , EGF and Il-1 by inflammatory cells seems to be an important factor for the hyperproliferative behavior of cholesteatoma epithelium . Our findings could contribute to the pathogenesis of middle ear cholesteatoma and give a possible explanation for the sustained progression of its growth leading to displacement of the middle ear mucosa ."
],
"offsets": [
[
0,
1296
]
]
}
] |
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] |
[] |
[] |
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HNO.70450638.eng.abstr
|
HNO.70450638.eng.abstr
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[
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"Diagnostics of developmental speech- and language disorders is based primarily on the criteria severity of involvement and pattern . Regarding phonological disorders single word articulation tests are widely used because of efficiency considerations . However they are insufficient for ICD-10 diagnostics , because severity of involvement and pattern are influenced from the fact that children are spontaneously talking or giving single word responses . \" Percentage of Consonants Correct ( PCC ) \" and \" Percentage of Consonants Correct for early , middle and late consonants \" are described as an articulation competence metric , whereas \" Natural Process Analysis \" is proposed to describe the pattern of the disorder . Three case studies are used to outline the methods . Data show that \" Percentage of Consonants Correct \" is a good metric to index severity of involvement and \" Natural Process Analysis \" is a prerequisite to describe the pattern of the disorder ."
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"type": "analyzes",
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"arg2_id": "HNO.70450638.eng.abstr-s6-t1",
"normalized": []
},
{
"id": "HNO.70450638.eng.abstr-s6-r5-t3.1-t1.1",
"type": "associated_with",
"arg1_id": "HNO.70450638.eng.abstr-s6-t3",
"arg2_id": "HNO.70450638.eng.abstr-s6-t1",
"normalized": []
},
{
"id": "HNO.70450638.eng.abstr-s6-r6-t3.1-t2.1",
"type": "isa",
"arg1_id": "HNO.70450638.eng.abstr-s6-t3",
"arg2_id": "HNO.70450638.eng.abstr-s6-t2",
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},
{
"id": "HNO.70450638.eng.abstr-s6-r7-t1.1-t3.1",
"type": "associated_with",
"arg1_id": "HNO.70450638.eng.abstr-s6-t1",
"arg2_id": "HNO.70450638.eng.abstr-s6-t3",
"normalized": []
},
{
"id": "HNO.70450638.eng.abstr-s6-r8-t1.1-t2.1",
"type": "associated_with",
"arg1_id": "HNO.70450638.eng.abstr-s6-t1",
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},
{
"id": "HNO.70450638.eng.abstr-s6-r9-t1.1-t2.1",
"type": "isa",
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"arg2_id": "HNO.70450638.eng.abstr-s6-t2",
"normalized": []
}
] |
HNO.70450643.eng.abstr
|
HNO.70450643.eng.abstr
|
[
{
"id": "HNO.70450643.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Different types of gunshot injuries caused by warning weapons are demonstrated . Most important are contact shots , causing major tissue damage that can differ from that caused by classical projectiles . Possible consequences , besides direct trauma to the eye and ear , are airway distress because of extensive swelling and rupture of major neck vessels . The detailed examination includes endoscopy and radiologic imaging . Any major permanent cavity in the tissue bears a high risk of wound infection . For different reasons the fact of a gunshot wound may be kept secret by the victims ."
],
"offsets": [
[
0,
591
]
]
}
] |
[
{
"id": "HNO.70450643.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"injuries"
],
"offsets": [
[
27,
35
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0175677"
},
{
"db_name": "UMLS",
"db_id": "C0021501"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"gunshot injuries"
],
"offsets": [
[
19,
35
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0043252"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"tissue"
],
"offsets": [
[
130,
136
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0040300"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"direct"
],
"offsets": [
[
236,
242
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0700157"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"trauma"
],
"offsets": [
[
243,
249
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0021501"
},
{
"db_name": "UMLS",
"db_id": "C0043251"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"eye"
],
"offsets": [
[
257,
260
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0015392"
},
{
"db_name": "UMLS",
"db_id": "C0496836"
},
{
"db_name": "UMLS",
"db_id": "C0023924"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"ear"
],
"offsets": [
[
265,
268
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0013443"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s3-t5",
"type": "umlsterm",
"text": [
"rupture"
],
"offsets": [
[
325,
332
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0035955"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s3-t6",
"type": "umlsterm",
"text": [
"neck"
],
"offsets": [
[
342,
346
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0027530"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s3-t7",
"type": "umlsterm",
"text": [
"vessels"
],
"offsets": [
[
347,
354
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0005847"
},
{
"db_name": "UMLS",
"db_id": "C0148346"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"endoscopy"
],
"offsets": [
[
391,
400
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0014245"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"imaging"
],
"offsets": [
[
416,
423
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0011923"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"tissue"
],
"offsets": [
[
460,
466
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0040300"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"risk"
],
"offsets": [
[
480,
484
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0035647"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s5-t3",
"type": "umlsterm",
"text": [
"wound"
],
"offsets": [
[
488,
493
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0021501"
},
{
"db_name": "UMLS",
"db_id": "C0043250"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s5-t4",
"type": "umlsterm",
"text": [
"infection"
],
"offsets": [
[
494,
503
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0021311"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s5-t5",
"type": "umlsterm",
"text": [
"risk of"
],
"offsets": [
[
480,
487
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0035647"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s5-t6",
"type": "umlsterm",
"text": [
"wound infection"
],
"offsets": [
[
488,
503
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0043241"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s6-t1",
"type": "umlsterm",
"text": [
"wound"
],
"offsets": [
[
550,
555
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0021501"
},
{
"db_name": "UMLS",
"db_id": "C0043250"
}
]
},
{
"id": "HNO.70450643.eng.abstr-s6-t2",
"type": "umlsterm",
"text": [
"gunshot wound"
],
"offsets": [
[
542,
555
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0043252"
}
]
}
] |
[] |
[] |
[
{
"id": "HNO.70450643.eng.abstr-s3-r1-t7.2-t2.1",
"type": "causes",
"arg1_id": "HNO.70450643.eng.abstr-s3-t7",
"arg2_id": "HNO.70450643.eng.abstr-s6-t2",
"normalized": []
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{
"id": "HNO.70450643.eng.abstr-s3-r2-t3.1-t3.3",
"type": "part_of",
"arg1_id": "HNO.70450643.eng.abstr-s5-t3",
"arg2_id": "HNO.70450643.eng.abstr-s3-t3",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r3-t7.1-t1.1",
"type": "location_of",
"arg1_id": "HNO.70450643.eng.abstr-s3-t7",
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{
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},
{
"id": "HNO.70450643.eng.abstr-s3-r5-t3.1-t6.1",
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"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r6-t7.2-t3.2",
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"arg1_id": "HNO.70450643.eng.abstr-s3-t7",
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},
{
"id": "HNO.70450643.eng.abstr-s3-r7-t7.1-t3.3",
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"arg1_id": "HNO.70450643.eng.abstr-s3-t7",
"arg2_id": "HNO.70450643.eng.abstr-s3-t3",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r8-t7.2-t2.1",
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"arg1_id": "HNO.70450643.eng.abstr-s3-t7",
"arg2_id": "HNO.70450643.eng.abstr-s6-t2",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r9-t7.2-t5.1",
"type": "treats",
"arg1_id": "HNO.70450643.eng.abstr-s3-t7",
"arg2_id": "HNO.70450643.eng.abstr-s5-t5",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r10-t7.1-t3.2",
"type": "location_of",
"arg1_id": "HNO.70450643.eng.abstr-s3-t7",
"arg2_id": "HNO.70450643.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r11-t3.1-t7.2",
"type": "produces",
"arg1_id": "HNO.70450643.eng.abstr-s5-t3",
"arg2_id": "HNO.70450643.eng.abstr-s3-t7",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r12-t6.1-t7.1",
"type": "adjacent_to",
"arg1_id": "HNO.70450643.eng.abstr-s5-t6",
"arg2_id": "HNO.70450643.eng.abstr-s3-t7",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r14-t3.2-t3.3",
"type": "part_of",
"arg1_id": "HNO.70450643.eng.abstr-s5-t3",
"arg2_id": "HNO.70450643.eng.abstr-s3-t3",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r15-t3.1-t2.1",
"type": "location_of",
"arg1_id": "HNO.70450643.eng.abstr-s5-t3",
"arg2_id": "HNO.70450643.eng.abstr-s6-t2",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r16-t7.1-t6.1",
"type": "adjacent_to",
"arg1_id": "HNO.70450643.eng.abstr-s3-t7",
"arg2_id": "HNO.70450643.eng.abstr-s5-t6",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r17-t6.1-t5.1",
"type": "location_of",
"arg1_id": "HNO.70450643.eng.abstr-s5-t6",
"arg2_id": "HNO.70450643.eng.abstr-s5-t5",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r18-t7.2-t1.1",
"type": "causes",
"arg1_id": "HNO.70450643.eng.abstr-s3-t7",
"arg2_id": "HNO.70450643.eng.abstr-s6-t1",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r19-t1.1-t3.2",
"type": "disrupts",
"arg1_id": "HNO.70450643.eng.abstr-s6-t1",
"arg2_id": "HNO.70450643.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r21-t6.1-t3.1",
"type": "adjacent_to",
"arg1_id": "HNO.70450643.eng.abstr-s5-t6",
"arg2_id": "HNO.70450643.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r22-t1.1-t7.1",
"type": "disrupts",
"arg1_id": "HNO.70450643.eng.abstr-s6-t1",
"arg2_id": "HNO.70450643.eng.abstr-s3-t7",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r23-t3.2-t5.1",
"type": "location_of",
"arg1_id": "HNO.70450643.eng.abstr-s5-t3",
"arg2_id": "HNO.70450643.eng.abstr-s5-t5",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r24-t7.1-t3.2",
"type": "part_of",
"arg1_id": "HNO.70450643.eng.abstr-s3-t7",
"arg2_id": "HNO.70450643.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r25-t7.2-t1.1",
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"arg1_id": "HNO.70450643.eng.abstr-s3-t7",
"arg2_id": "HNO.70450643.eng.abstr-s6-t1",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r26-t1.1-t7.2",
"type": "interacts_with",
"arg1_id": "HNO.70450643.eng.abstr-s6-t1",
"arg2_id": "HNO.70450643.eng.abstr-s3-t7",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r27-t3.2-t1.1",
"type": "associated_with",
"arg1_id": "HNO.70450643.eng.abstr-s5-t3",
"arg2_id": "HNO.70450643.eng.abstr-s6-t1",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r28-t3.2-t5.1",
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"arg1_id": "HNO.70450643.eng.abstr-s5-t3",
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"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r29-t6.1-t1.1",
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"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r30-t7.1-t2.1",
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"arg1_id": "HNO.70450643.eng.abstr-s3-t7",
"arg2_id": "HNO.70450643.eng.abstr-s6-t2",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r31-t7.2-t3.2",
"type": "disrupts",
"arg1_id": "HNO.70450643.eng.abstr-s3-t7",
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"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r32-t6.1-t3.2",
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"arg1_id": "HNO.70450643.eng.abstr-s5-t6",
"arg2_id": "HNO.70450643.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r33-t6.1-t3.2",
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},
{
"id": "HNO.70450643.eng.abstr-s3-r35-t3.2-t1.1",
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},
{
"id": "HNO.70450643.eng.abstr-s3-r36-t1.1-t5.1",
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},
{
"id": "HNO.70450643.eng.abstr-s3-r37-t1.1-t2.1",
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},
{
"id": "HNO.70450643.eng.abstr-s3-r38-t3.1-t5.1",
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"arg1_id": "HNO.70450643.eng.abstr-s5-t3",
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"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r39-t3.2-t3.3",
"type": "affects",
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},
{
"id": "HNO.70450643.eng.abstr-s3-r40-t3.2-t7.2",
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},
{
"id": "HNO.70450643.eng.abstr-s3-r41-t1.1-t3.2",
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"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r42-t1.1-t3.1",
"type": "disrupts",
"arg1_id": "HNO.70450643.eng.abstr-s6-t1",
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"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r43-t1.1-t3.2",
"type": "affects",
"arg1_id": "HNO.70450643.eng.abstr-s6-t1",
"arg2_id": "HNO.70450643.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r44-t3.3-t3.2",
"type": "causes",
"arg1_id": "HNO.70450643.eng.abstr-s3-t3",
"arg2_id": "HNO.70450643.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "HNO.70450643.eng.abstr-s3-r45-t7.2-t3.2",
"type": "diagnoses",
"arg1_id": "HNO.70450643.eng.abstr-s3-t7",
"arg2_id": "HNO.70450643.eng.abstr-s5-t3",
"normalized": []
},
{
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HNO.70450682.eng.abstr
|
HNO.70450682.eng.abstr
|
[
{
"id": "HNO.70450682.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The frequency and possible causes of erosion and necrosis of the long process of the incus induced by various types of prostheses following stapes surgery for otosclerosis are discussed . Between 1987 and 1995 , 1144 stapes operations were performed including 117 revisions of stapes surgery performed by third parties and 27 revisions performed by the author . For the first time , necrosis of the long process of the incus caused by teflon-platinum piston is described on the basis of findings in five cases , in which the platinum loop had completely transmigrated the incudal process in a medial direction . By using pictures of the teflon-platinum piston and a gold piston taken by a scanning electron microscopy and a comparison between the use of a teflon-wire piston and a gold piston in two operations , an hypothesis is made that the winding grooves in the surface of the teflon shaft together with impaired middle ear mechanics were the main causes of a scar being contracted in the direction of the oval window niche with resulting necrosis of the incudal process . Requirements for an optimum stapes prosthesis are summarized as a result of the operative observations made ."
],
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[
0,
1187
]
]
}
] |
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] |
[] |
[] |
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HNO.70450690.eng.abstr
|
HNO.70450690.eng.abstr
|
[
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"Jastreboff und Hazell [ 9 ] developed a neurophysiological approach to tinnitus perception , including the important role of the central nervous system in the maintenance and intrusiveness of tinnitus . They introduced tinnitus-retraining therapy , consisting of four different strategies : ( 1 ) directive and person-centered counseling ; ( 2 ) hearing aids and/or noise generators and/or environmental sounds ; ( 3 ) psychological therapy ; ( 4 ) adjacent therapies . Tinnitus should not be masked as with a tinnitus-masker , but must be able to be heard in addition to the noise ! A noise generator or hearing aid should be worn at least 6-8 h per day over a period of up to 18 months . In additions several clinical visits are required in order to reinforce the counseling . The actual results show complete tinnitus remission for about 20-30% and partial remission for 50-60% of the patients [ 6 ] . We report on a retrospective study in patients wearing hearing aids or tinnitus-maskers over a period of 3 years . We compared the results of patients using partial tinnitus masking to those using complete masking . The tinnitus-related and general psychological complaints were acquired by the 52-item tinnitus questionnaire developed by Hallam et al. [ 4 ] and modified by Goebel and Hiller [ 3 ] . To describe the dimensions of tinnitus-related distress the scales are labelled emotional distress , cognitive distress , emotional and cognitive distress , intrusiveness , auditory perceptual difficulties , sleep disturbance and somatic complaints . Positive changes for the global tinnitus questionnaire score of more than 10 points are significant in the dimensions of tinnitus-related distress and are described as partial tinnitus-reduction . The group with partial masking effects can be compared to those performing retraining therapy to day because directive and personal centered counseling were integrated for all patients . Patients reporting partial masking effects through their aids ( hearing aid or noise generator ) showed more effective treatment results ( reduced or disappeared tinnitus ) than those using complete masking effects ( P 0.05 ) . The reported results are improved by current investigations in Germany showing about 20-30% tinnitus remission and 50-60% significant reduction after 1 year of treatment [ 1 ] . Further scientific investigations must be carried out to evaluate the appropriateness and effectiveness of the retraining therapy and with regard to unique quality standards ."
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HNO.70450702.eng.abstr
|
HNO.70450702.eng.abstr
|
[
{
"id": "HNO.70450702.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A prospective study was performed to compare the sensitivity and accuracy of ultrasound ( US ) , computed tomography ( CT ) , and single photon emission computed tomography ( SPECT ) as a bone scan to detect subclinical invasion of the mandible by squamous cell carcinoma of the oral cavity and floor of mouth ."
],
"offsets": [
[
0,
311
]
]
}
] |
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},
{
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{
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{
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{
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{
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{
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},
{
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},
{
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2,
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{
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{
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},
{
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{
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},
{
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],
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},
{
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],
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]
],
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{
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}
]
}
] |
[] |
[] |
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HNO.70450712.eng.abstr
|
HNO.70450712.eng.abstr
|
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"According to Negus and Pressman the sphincter systems of the vocal folds and the ventricular folds form a respiratory \" laryngeal double valve function \" . Correspondingly , we found a physiological phonation system of the glottis and a pathological-compensatory one of the supraglottis . They appear to be regulated through an automatic phonatory control system with the glottal phonatory function evidently acting as sensor level . In order to confirm this hypothesis , objective voice analyses with glottal-relevant parameters of 26 voice-rehabilitated patients after minimally invasive laser surgery of glottal carcinomas are presented and integrated into a \" hoarseness diagram \" with the coordinates roughness and breathiness . Using statistically deliminated acoustic clusters , our data show a qualitative hierarchy of different postoperative phonation mechanisms . They demonstrate the influence of the vibratory capacity of glottal and supraglottal structures on the quality of the vibratory closure . Both functional parameters evidently determine the resulting voice quality in the sense of our hypothesis ."
],
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0,
1119
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]
}
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] |
[] |
[] |
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"arg2_id": "HNO.70450712.eng.abstr-s4-t9",
"normalized": []
},
{
"id": "HNO.70450712.eng.abstr-s4-r24-t3.1-t1.1",
"type": "uses",
"arg1_id": "HNO.70450712.eng.abstr-s5-t3",
"arg2_id": "HNO.70450712.eng.abstr-s7-t1",
"normalized": []
},
{
"id": "HNO.70450712.eng.abstr-s4-r25-t6.2-t3.1",
"type": "associated_with",
"arg1_id": "HNO.70450712.eng.abstr-s4-t6",
"arg2_id": "HNO.70450712.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "HNO.70450712.eng.abstr-s4-r26-t3.1-t9.1",
"type": "performs",
"arg1_id": "HNO.70450712.eng.abstr-s5-t3",
"arg2_id": "HNO.70450712.eng.abstr-s4-t9",
"normalized": []
},
{
"id": "HNO.70450712.eng.abstr-s4-r27-t5.1-t6.1",
"type": "issue_in",
"arg1_id": "HNO.70450712.eng.abstr-s5-t5",
"arg2_id": "HNO.70450712.eng.abstr-s4-t6",
"normalized": []
},
{
"id": "HNO.70450712.eng.abstr-s4-r28-t3.1-t2.1",
"type": "measures",
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"arg2_id": "HNO.70450712.eng.abstr-s7-t2",
"normalized": []
},
{
"id": "HNO.70450712.eng.abstr-s4-r29-t9.1-t3.1",
"type": "affects",
"arg1_id": "HNO.70450712.eng.abstr-s4-t9",
"arg2_id": "HNO.70450712.eng.abstr-s5-t3",
"normalized": []
},
{
"id": "HNO.70450712.eng.abstr-s5-r1-t3.1-t5.1",
"type": "conceptual_part_of",
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"arg2_id": "HNO.70450712.eng.abstr-s5-t5",
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},
{
"id": "HNO.70450712.eng.abstr-s5-r2-t5.1-t1.1",
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},
{
"id": "HNO.70450712.eng.abstr-s5-r3-t1.1-t5.1",
"type": "result_of",
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"arg2_id": "HNO.70450712.eng.abstr-s5-t5",
"normalized": []
},
{
"id": "HNO.70450712.eng.abstr-s5-r4-t2.1-t5.1",
"type": "measurement_of",
"arg1_id": "HNO.70450712.eng.abstr-s7-t2",
"arg2_id": "HNO.70450712.eng.abstr-s5-t5",
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},
{
"id": "HNO.70450712.eng.abstr-s5-r5-t5.1-t3.1",
"type": "conceptual_part_of",
"arg1_id": "HNO.70450712.eng.abstr-s5-t5",
"arg2_id": "HNO.70450712.eng.abstr-s5-t3",
"normalized": []
}
] |
HNO.70450719.eng.abstr
|
HNO.70450719.eng.abstr
|
[
{
"id": "HNO.70450719.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Cervical lymphadenopathies are widespread diseases in otorhinolaryngology . There are many differential diagnoses which have to be considered when swelling persists . To gain further information it is advisable to perform sonographically controlled fine needle aspiration biopsy ( FNP ) . If there is no reliable result , it is necessary to remove a lymph node . We report on the rare case of isolated histiocytosis X in lymph nodes . A 63-year-old male had noticed a swelling of the right side of the neck about 6 weeks previously . The preliminary examinations ( FNP/blood examinations ) revealed no pathological findings . Only the histological examination delivered the diagnosis of histiocytosis X. Systemic manifestation was excluded by staging examinations . No further therapy was necessary after lymph node extirpation . The report demonstrates how to diagnose and treat this rare disease ."
],
"offsets": [
[
0,
899
]
]
}
] |
[
{
"id": "HNO.70450719.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"lymphadenopathies"
],
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[
9,
26
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0024228"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"diseases"
],
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[
42,
50
]
],
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{
"db_name": "UMLS",
"db_id": "C0012634"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"otorhinolaryngology"
],
"offsets": [
[
54,
73
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0086747"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"differential diagnoses"
],
"offsets": [
[
91,
113
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0011906"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"needle"
],
"offsets": [
[
254,
260
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0027551"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"aspiration"
],
"offsets": [
[
261,
271
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0004056"
},
{
"db_name": "UMLS",
"db_id": "C0004048"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"biopsy"
],
"offsets": [
[
272,
278
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0220797"
},
{
"db_name": "UMLS",
"db_id": "C0005558"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s3-t4",
"type": "umlsterm",
"text": [
"aspiration biopsy"
],
"offsets": [
[
261,
278
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0005560"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"lymph"
],
"offsets": [
[
350,
355
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0024202"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"lymph node"
],
"offsets": [
[
350,
360
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0024204"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s5-t1",
"type": "umlsterm",
"text": [
"lymph"
],
"offsets": [
[
421,
426
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0024202"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"histiocytosis X"
],
"offsets": [
[
402,
417
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0019621"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s5-t3",
"type": "umlsterm",
"text": [
"lymph nodes"
],
"offsets": [
[
421,
432
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0024204"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s6-t1",
"type": "umlsterm",
"text": [
"male"
],
"offsets": [
[
449,
453
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0024554"
},
{
"db_name": "UMLS",
"db_id": "C0086582"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s6-t2",
"type": "umlsterm",
"text": [
"right"
],
"offsets": [
[
484,
489
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0035621"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s6-t3",
"type": "umlsterm",
"text": [
"neck"
],
"offsets": [
[
502,
506
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0027530"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s7-t1",
"type": "umlsterm",
"text": [
"findings"
],
"offsets": [
[
615,
623
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0243095"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s8-t1",
"type": "umlsterm",
"text": [
"diagnosis"
],
"offsets": [
[
674,
683
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0011900"
},
{
"db_name": "UMLS",
"db_id": "C0348026"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s9-t1",
"type": "umlsterm",
"text": [
"therapy"
],
"offsets": [
[
777,
784
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0087111"
},
{
"db_name": "UMLS",
"db_id": "C0039798"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s9-t2",
"type": "umlsterm",
"text": [
"lymph"
],
"offsets": [
[
805,
810
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0024202"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s9-t3",
"type": "umlsterm",
"text": [
"lymph node"
],
"offsets": [
[
805,
815
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0024204"
}
]
},
{
"id": "HNO.70450719.eng.abstr-s10-t1",
"type": "umlsterm",
"text": [
"disease"
],
"offsets": [
[
890,
897
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0012634"
}
]
}
] |
[] |
[] |
[
{
"id": "HNO.70450719.eng.abstr-s1-r1-t1.1-t3.1",
"type": "issue_in",
"arg1_id": "HNO.70450719.eng.abstr-s10-t1",
"arg2_id": "HNO.70450719.eng.abstr-s9-t3",
"normalized": []
},
{
"id": "HNO.70450719.eng.abstr-s1-r2-t2.1-t3.1",
"type": "issue_in",
"arg1_id": "HNO.70450719.eng.abstr-s9-t2",
"arg2_id": "HNO.70450719.eng.abstr-s9-t3",
"normalized": []
},
{
"id": "HNO.70450719.eng.abstr-s3-r1-t2.2-t2.1",
"type": "result_of",
"arg1_id": "HNO.70450719.eng.abstr-s3-t2",
"arg2_id": "HNO.70450719.eng.abstr-s9-t2",
"normalized": []
},
{
"id": "HNO.70450719.eng.abstr-s3-r2-t2.1-t2.2",
"type": "result_of",
"arg1_id": "HNO.70450719.eng.abstr-s9-t2",
"arg2_id": "HNO.70450719.eng.abstr-s3-t2",
"normalized": []
},
{
"id": "HNO.70450719.eng.abstr-s4-r1-t1.1-t2.1",
"type": "connected_to",
"arg1_id": "HNO.70450719.eng.abstr-s10-t1",
"arg2_id": "HNO.70450719.eng.abstr-s9-t2",
"normalized": []
},
{
"id": "HNO.70450719.eng.abstr-s4-r2-t2.1-t1.1",
"type": "connected_to",
"arg1_id": "HNO.70450719.eng.abstr-s9-t2",
"arg2_id": "HNO.70450719.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "HNO.70450719.eng.abstr-s5-r1-t2.1-t1.1",
"type": "produces",
"arg1_id": "HNO.70450719.eng.abstr-s9-t2",
"arg2_id": "HNO.70450719.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "HNO.70450719.eng.abstr-s5-r2-t1.1-t3.1",
"type": "connected_to",
"arg1_id": "HNO.70450719.eng.abstr-s10-t1",
"arg2_id": "HNO.70450719.eng.abstr-s9-t3",
"normalized": []
},
{
"id": "HNO.70450719.eng.abstr-s5-r3-t1.1-t2.1",
"type": "causes",
"arg1_id": "HNO.70450719.eng.abstr-s10-t1",
"arg2_id": "HNO.70450719.eng.abstr-s9-t2",
"normalized": []
},
{
"id": "HNO.70450719.eng.abstr-s5-r4-t3.1-t1.1",
"type": "connected_to",
"arg1_id": "HNO.70450719.eng.abstr-s9-t3",
"arg2_id": "HNO.70450719.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "HNO.70450719.eng.abstr-s5-r5-t3.1-t2.1",
"type": "location_of",
"arg1_id": "HNO.70450719.eng.abstr-s9-t3",
"arg2_id": "HNO.70450719.eng.abstr-s9-t2",
"normalized": []
},
{
"id": "HNO.70450719.eng.abstr-s9-r1-t1.1-t3.1",
"type": "connected_to",
"arg1_id": "HNO.70450719.eng.abstr-s10-t1",
"arg2_id": "HNO.70450719.eng.abstr-s9-t3",
"normalized": []
},
{
"id": "HNO.70450719.eng.abstr-s9-r2-t3.1-t1.1",
"type": "location_of",
"arg1_id": "HNO.70450719.eng.abstr-s9-t3",
"arg2_id": "HNO.70450719.eng.abstr-s10-t1",
"normalized": []
},
{
"id": "HNO.70450719.eng.abstr-s9-r3-t3.1-t1.1",
"type": "connected_to",
"arg1_id": "HNO.70450719.eng.abstr-s9-t3",
"arg2_id": "HNO.70450719.eng.abstr-s10-t1",
"normalized": []
}
] |
HNO.70450749.eng.abstr
|
HNO.70450749.eng.abstr
|
[
{
"id": "HNO.70450749.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Hearing aids have fundamental disadvantages : ( 1 ) stigmatization of the patient ; ( 2 ) the sound is often found to be unsatisfactory due to the limited frequency range and undesired distortion ; ( 3 ) in many patients , the ear canal fitting device generally necessary leads to an occlusion effect ; ( 4 ) acoustic feedback when amplification is high . Conventional hearing aids transmit sound into the ear canal via a small microphone . Sound has the disadvantage of requiring high output sound pressure levels for its transmission . This along with the necessary miniaturization of the loudspeaker as well as the resonances and reflections in the closed ear canal contribute to the disadvantages mentioned . In contrast , implantable hearing aids do not make sound signals but micromechanical vibrations . An implantable hearing aid has an electromechanical transducer instead of the loudspeaker of a conventional hearing aid . The hearing signal does not leave the transducer as sound but as a mechanical vibration which is directly coupled to the auditory system bypassing the air . This implantable hearing aid is either coupled to the tympanic membrane , the ossicular chain , the perilymph of the inner ear , or the skull ."
],
"offsets": [
[
0,
1233
]
]
}
] |
[
{
"id": "HNO.70450749.eng.abstr-s1-t1",
"type": "umlsterm",
"text": [
"aids"
],
"offsets": [
[
8,
12
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0021588"
},
{
"db_name": "UMLS",
"db_id": "C0001175"
}
]
},
{
"id": "HNO.70450749.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"stigmatization"
],
"offsets": [
[
52,
66
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0038330"
}
]
},
{
"id": "HNO.70450749.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"patient"
],
"offsets": [
[
74,
81
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "HNO.70450749.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"sound"
],
"offsets": [
[
94,
99
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0037709"
}
]
},
{
"id": "HNO.70450749.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"frequency"
],
"offsets": [
[
155,
164
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0376249"
}
]
},
{
"id": "HNO.70450749.eng.abstr-s1-t6",
"type": "umlsterm",
"text": [
"patients"
],
"offsets": [
[
212,
220
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0030705"
}
]
},
{
"id": "HNO.70450749.eng.abstr-s1-t7",
"type": "umlsterm",
"text": [
"ear"
],
"offsets": [
[
227,
230
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0013443"
}
]
},
{
"id": "HNO.70450749.eng.abstr-s1-t8",
"type": "umlsterm",
"text": [
"fitting"
],
"offsets": [
[
237,
244
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0036572"
}
]
},
{
"id": "HNO.70450749.eng.abstr-s1-t9",
"type": "umlsterm",
"text": [
"device"
],
"offsets": [
[
245,
251
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0699733"
},
{
"db_name": "UMLS",
"db_id": "C0220819"
}
]
},
{
"id": "HNO.70450749.eng.abstr-s1-t10",
"type": "umlsterm",
"text": [
"leads"
],
"offsets": [
[
272,
277
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0023175"
}
]
},
{
"id": "HNO.70450749.eng.abstr-s1-t11",
"type": "umlsterm",
"text": [
"acoustic"
],
"offsets": [
[
309,
317
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0001166"
}
]
},
{
"id": "HNO.70450749.eng.abstr-s1-t12",
"type": "umlsterm",
"text": [
"feedback"
],
"offsets": [
[
318,
326
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0015744"
}
]
},
{
"id": "HNO.70450749.eng.abstr-s1-t13",
"type": "umlsterm",
"text": [
"Hearing aids"
],
"offsets": [
[
0,
12
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0018768"
}
]
},
{
"id": "HNO.70450749.eng.abstr-s1-t14",
"type": "umlsterm",
"text": [
"ear canal"
],
"offsets": [
[
227,
236
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0013444"
}
]
},
{
"id": "HNO.70450749.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"hearing"
],
"offsets": [
[
369,
376
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0018767"
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] |
[] |
[] |
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HNO.70450758.eng.abstr
|
HNO.70450758.eng.abstr
|
[
{
"id": "HNO.70450758.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Active hearing implants have been developed to varying degrees for conductive hearing loss as well as for sensorineural hearing loss . Implants for conductive hearing loss match impedance transformation by the middle ear . They will be referred to as ITI ( impedance transformation implants ) . Three partial ITIs have been developed for routine clinical use : the Swedish transcutaneous BAHA , the American subcutaneous AUDIANT , and the Japanese P-MEI . Of greater importance with respect to the number of patients are electronic implants for sensorineural hearing loss . These implants are designed to replace parts of the function of the cochlea amplifier ( CA ) . Therefore , in this study , they will be called CAI ( cochlea amplifier implant ) . The CAI consist of four parts : ( 1 ) transducer , ( 2 ) microphone , ( 3 ) control unit , and ( 4 ) battery . A CAI for routine clinical use does not yet exist . Two transducer principles have thus far been developed for use in CAIs : the electromagnetic ( EM ) and the piezoelectric ( PE ) principle . Most of the transducers that have been described are EM transducers . The American Maniglia implant and the American floating mass transducer have been tested in humans . Both belong to the category of high energy consuming ( HEC ) implants with a limited frequency range that does not contain the whole speech spectrum . This is in contrast to the Canadian electromagnetic Fredrickson-HEC implant which is capable of transmitting broad band signals of up to 10 kHz . All ot he HEC-EM transducers lack an implantable microphone and an implantable battery . The German CAI , one of the piezoelectrical implants , was recently implanted acutely in humans . It consists of a piezoelectrical , ossicle coupled , low energy consuming ( LEC ) transducer , as well as an implantable microphone . It allows a broadband signal of up to 10 kHz , yet at a considerably lower level of energy ."
],
"offsets": [
[
0,
1938
]
]
}
] |
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[] |
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HNO.70450769.eng.abstr
|
HNO.70450769.eng.abstr
|
[
{
"id": "HNO.70450769.eng.abstr-passage-0",
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"text": [
"The perspectives for active hearing implants lie in the treatment of patients with sensorineural hearing loss ( SNHL ) . The majority of patients with SNHL suffer from a cochlea amplifier ( CA ) failure which is discernible by a positive recruitment and loss of otoacoustic emissions ( OAE ) . Therefore , the electronic implant is expected to partially replace functions of the CA . Thus , the implant is thought to function as a CAI ( cochlea amplifier implant ) . An approved implant for routine use is not yet available . Clinical studies have thus far only used the high energy consuming ( HEC ) , narrow-band , electromagnetic floating-mass transducer , as well as the Maniglia-HEC implant . The high energie consuming , yet broadband Canadian Fredrickson implant is soon to be used in humans . Of the piezoelectrical implants , a German CAI ( Tuebingen implant ) at present consisting of a piezoelectrical transducer and a microphone has thus far been acutely implanted in first patient . It is a low energy consuming ( LEC ) , broad-band implantable system for patients with sensorineural hearing loss ."
],
"offsets": [
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0,
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]
]
}
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[] |
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HNO.70450775.eng.abstr
|
HNO.70450775.eng.abstr
|
[
{
"id": "HNO.70450775.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In order to overcome the disadvantages of hearing aids , a significant amount of research aimed at replacing them by implanted ossicular-coupled electronic hearing devices is being carried out . The technical and audiological demands on the electromechanical transducer of an implantable hearing aid for moderate to severe sensorineural hearing losses include high transmission quality of the equivalent sound-pressure level without significant linear or nonlinear distortion , and an energy balance suitable for implantation . Fundamental specifications for a transducer are a high spectral bandwidth of up to 10 kHz , an elongation amplitude of at least 100 nm within this range , a small ripple of the elongation frequence response of around +/- 3 dB , a total harmonic distortion ( THD ) of less than 0.5% , and a maximum electric power consumption of 0.1 mW . The demands on construction , such as hermetic sealing , biocompatibility , and biostability , are also discussed in detail . It appears that optimum transducer design is essentially a compromise between the physical requirements which are in part conflicting regardless of the transducer principle employed ."
],
"offsets": [
[
0,
1174
]
]
}
] |
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] |
[] |
[] |
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HNO.70450792.eng.abstr
|
HNO.70450792.eng.abstr
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[
{
"id": "HNO.70450792.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Implantable hearing aids can form the basis of new surgical techniques for dealing with hearing problems originating in the inner ear , provided they are fully implantable . Accordingly , a comprehensive , interdisciplinary , combined project was initiated at the ENT clinic of the University of Tuebingen which was to conclude with operations to improve hearing via fully implantable hearing aids . A novel electromechanical transducer for implantable hearing aids based on the piezoelectric principle is described . Unlike the piezoelectric transducers reported so far , this transducer does not rely on the bimorphic principle but on a circle-shaped , heteromorphic combination system consisting of a piezoceramic disc and metal membrane . The transducer can be hermetically sealed and is designed for implantation into the mastoid . Transfer of mechanical oscillations to an ossicle in the middle ear is effected by a directly fixed coupling rod or via suitable coupling elements . The transducer is highly tuned with a resonance frequency at the upper end of the spectral transfer range ( greater than 10 kHz ) . Below this resonance and down to low frequencies , the frequency response of elongation is smooth with amplitudes of around 20 nm . At low and middle frequencies of up to 1 kHz , these vibration amplitudes correspond to sound-pressure levels of around 90 dB SPL . At higher frequencies of up to 10 kHz , the output level increases to about 130 dB SPL . Nonlinear distortions are also very small at the highest levels ( less than 0.1% ) throughout the whole transfer range . Electric power consumption at maximum levels is in the range of a few microwatts and is therefore significantly lower than that of electromagnetic systems . Particularly , this makes it possible to use the transducer in fully implantable hearing aids for rehabilitation of sensorineural hearing loss ."
],
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[
0,
1893
]
]
}
] |
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] |
HNO.70450816.eng.abstr
|
HNO.70450816.eng.abstr
|
[
{
"id": "HNO.70450816.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Fully implantable hearing aids and cochlea implants of the future require an implantable microphone . A hermetically sealed implantable microphone based on the idea of a microphone implanted in the posterior wall of the auditory canal , as suggested by Ohno et al. in 1988 , is presented . Through consistent technological and clinical design optimization , it was possible to achieve a membrane diameter of only 4.5 mm ( as opposed to 8 mm in the Japanese system ) and a significant volume reduction of nearly 50% . The microphone weights only 0.4 g . In spite of this miniaturization , the performance characteristics of the microphone equal those of the Japanese model or are superior . The sound-pressure transfer function shows a very small ripple and the bandwidth amounts to approximately 10 kHz . Because of its high tuning and high no-load resonance frequency , the microphone is mostly insensitive to post-operational changes to the loading mass on the microphone membrane initiated by the covering skin of the auditory canal . The sound-pressure transfer factor at 1000 Hz is approximately 1.5 mV/Pa . Using different manufacturing technologies , this value can be increased in the range of 6-8 dB with a corresponding reduction in bandwidth . Due to the small mass , the microphone is highly insensitive to environmental mechanical disturbances . The module is made of pure titanium and is hermetically sealed according to Mil-Std 883 D. Full metal encapsulation and additional internal electronic components protect the microphone well against environmental electromagnetic influences ( EMC ) ."
],
"offsets": [
[
0,
1607
]
]
}
] |
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] |
[] |
[] |
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] |
HNO.70450828.eng.abstr
|
HNO.70450828.eng.abstr
|
[
{
"id": "HNO.70450828.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Recently , we presented an implantable piezoelectrical hearing aid transducer . Its characteristics make it suitable for implantation in patients with sensorineural hearing loss . The transducer transmits micromechanical vibrations instead of sound into the hearing organ . Efficiency of the transducer implant was investigated in ten cat ears . After determining preoperative ( acoustical ) BERA threshold , the middle ear was opened and the piezoelectrical transducer coupled to various ossicles or the perilymph . BERA responses were recorded following stimulation of umbo , long incus process , stapes head , stapes foot plate , and vestibulum . By comparing the acoustical and mechanical threshold , a correlation was found between the stimulus level of acoustical and mechanical stimulation . An electrical transducer voltage of 1 Vrms* was equivalent to sound-pressure levels between 100 and 128 dB SPL at the tympanic membrane . To judge hearing impression , stimulus-dependent latencies of the early acoustically and mechanically evoked potentials ( waves P1 to P5) and their thresholds were analyzed . After coupling the piezoelectrical transducer to the long incus process , latencies corresponded well to stimulation . They were almost completely similar when the equivalent sound-pressure level of 100 dB SPL was achieved by the transducer voltage level ."
],
"offsets": [
[
0,
1368
]
]
}
] |
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] |
HNO.70450840.eng.abstr
|
HNO.70450840.eng.abstr
|
[
{
"id": "HNO.70450840.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Prerequisite to implantation of a piezoelectrical transducer of an implantable hearing aid is a shape allowing its implantation into human mastoid and middle ear . To approach this problem , a consecutive series of six transducer prototypes was created in an iterative process . Their functional geometry was evaluated in 50 human temporal bones . A shape for a functioning transducer was found which will enable implantation in 78% of the cases examined ( confidence interval : 61.5%-89.2%). It will allow simultaneous implantation of the transducer into the mastoid and microphone , which is situated transmastoidal in the posterior wall of the ear canal . Furthermore , the transducer may be coupled to the ossicular chain or the perilymph ."
],
"offsets": [
[
0,
744
]
]
}
] |
[
{
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"implantation"
],
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[
16,
28
]
],
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},
{
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"transducer"
],
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[
50,
60
]
],
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]
},
{
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"hearing"
],
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[
79,
86
]
],
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},
{
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"aid"
],
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[
87,
90
]
],
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{
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},
{
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],
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115,
127
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},
{
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],
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[] |
[] |
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] |
HNO.70450847.eng.abstr
|
HNO.70450847.eng.abstr
|
[
{
"id": "HNO.70450847.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Recently , an implantable hearing aid for rehabilitation of sensorineural hearing loss has been developed . One component of the device is the microphone for implantation into the posterior canal wall . The membrane of the microphone can be covered by skin , cartilage , or fascia , avoiding reduction in sound transmission at the same time . In the study presented here , the microphone was implanted into 50 cadaver specimens of human temporal bone . Localization of the microphone was determined by the anatomical situation of the facial nerve . The microphone and the piezoelectric transducer could be implanted in 78% of the temporal bones after total mastoidectomy . In the final version of the microphone , the size was 4.5 mm and total weight 400 mg ."
],
"offsets": [
[
0,
759
]
]
}
] |
[
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{
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37
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HNO.70450855.eng.abstr
|
HNO.70450855.eng.abstr
|
[
{
"id": "HNO.70450855.eng.abstr-passage-0",
"type": "abstract",
"text": [
"During routine middle ear surgery prototypes of implantable piezoelectric hearing aid transducers were coupled to the ossicular chain of 28 patients . Pure tone thresholds in a broad frequency range ( 250 Hz-8 kHz ) and perception of music were the basis of psychoacoustic evaluation of the transfer properties of the prototypes in this human study . The piezoelectric transducer reached an equivalent transducer sound-pressure level of up to 145 dB SPL and frequencies of 10 kHz . The dynamics for music reached 32 dB , which was identical with the results of the preoperative investigations using hi-fi headsets ( 33 dB ) . The low nonlinear distortions of around 0.1% and the frequency range up to 10 kHz are reflected in the positive evaluation of sound quality by 84% of the patients involved . The study is the basis for realizing a piezoelectric transducer designed for routine clinical implantations . The transducer is thought to be part of a totally implantable future hearing aid for rehabilitation of moderate and severe sensory neural hearing loss predominantly in the middle and high frequency range ."
],
"offsets": [
[
0,
1115
]
]
}
] |
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[] |
[] |
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HNO.70450867.eng.abstr
|
HNO.70450867.eng.abstr
|
[
{
"id": "HNO.70450867.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Special coupling devices made of pure gold or titanium have been developed to connect a new implantable hearing aid transducer ( Tuebingen implant ) to the ossicular chain . They allow piezotransducer probe-tip connection to the long process of the incus or the stapedial head . Similar to the design of conventional PORPs ( partial ossicular replacement prostheses ) , the coupling devices can be fixed at the ossicular chain , e.g. , with the eye loop of stapedial piston prostheses or the bell element of golden wire PORPs . A crimp technique allows connection between coupling device and transducer probe tip [ 5 ] . The main disadvantage in connecting the long process of the incus or the stapes having is to drill a dorsal tympanotomy in the posterior wall of the ear canal during surgery . The short distance between tympanotomy and N. facialis contains serious surgical risks . To avoid the risk of facial paralysis , Fredrickson's alternative coupling technique for the body of the incus is investigated in this paper [ 2 ] . In this case , the transducer probe tip will be positioned to the incus body and placed on its surface with controlled elastic displacement of the ossicular chain . The simple direct attachment of the probe-tip end on the surface of the incus , however , will not guarantee a stable long-term connection . Thus , by creating a conical , 0.5- to 0.7-mm-deep hole in the incus , the probe tip will be fitted much better . With a novel surgical Erbium-YAG laser this can be done in a contactless procedure . In this paper , first results of microsurgical laser applications with human temporal bones will be shown ."
],
"offsets": [
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0,
1647
]
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}
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[] |
[] |
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HNO.70450872.eng.abstr
|
HNO.70450872.eng.abstr
|
[
{
"id": "HNO.70450872.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A microphone constructed for implantation in the posterior wall of the auditory canal and a piezoelectric transducer serving as the main components of an implantable hearing aid were temporally implanted in five patients during middle ear surgery under local anesthesia . The microphone was positioned beneath the skin of the auditory canal such that it completely covered the microphone membrane . The vibratory element of the transducer was coupled to the malleus in four patients with normal ossicular chains and directly to the stapes in one patient with missing incus . The microphone and transducer were electrically connected with an external battery-driven signal amplifier . Speech material and music were presented in the operation room at a sound level of 65 dB SPL under free-field conditions . The patients had to estimate the quality of speech , music , and their own voice as well as the effects of bone-conducting noises . All patients were able to hear with the system . An intraoperative talk without vision contact was possible without any problems , as was understanding of numerals ( \" Freiburger Zahlentest \" ) . Perception of music was judged as \" clear and undistorted with all broadband component . \" The estimation was also valid for one patient with a sensorineural hearing loss . One patient declared the music to be \" a little of unnatural . \" Bone-conducted sound was estimated as normal in two patients , better than without an implant in one patient with sensorineural hearing loss , and \" somewhat metallic \" in another patient . Hearing the own voice was considered \" normal \" in two cases \" monotonous \" in one case , and \" a little bit roaring \" in another case . An amplification factor that can be technically realized in an implantable hearing aid was necessary for one of the patients with sensorineural hearing loss to perceive music at a pleasant volume . On the basis of this study , essential requirements for the construction of a fully implantable hearing aid are fulfilled ."
],
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0,
2021
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]
}
] |
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"id": "HNO.70450872.eng.abstr-s15-r2-t2.1-t1.1",
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"normalized": []
}
] |
HNO.70450891.eng.abstr
|
HNO.70450891.eng.abstr
|
[
{
"id": "HNO.70450891.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In Germany about 8500 dog-bite injuries in the face occur every year ; more than 50% of the victims are infants and schoolchildren . Besides dogs , other animals such as cats or horses may be responsible for these accidents . Even human bites are reported . The predominant areas are the nose and the auricles . The tissue defects may be superficial , but they can even cause amputations , including severe vascular and nerve or bony destruction . Systemic antibiotic therapy is needed when the wound is infected . The surgical approach to bite injuries includes local wound cleansing , careful excision of necrotic tissue and primary closure of the wound whenever possible . Regarding the importance of surgery in the head and neck area plastic-reconstructive techniques including autologous transplantations and various local or regional flaps should be used at the time the wound is first repaired ."
],
"offsets": [
[
0,
902
]
]
}
] |
[
{
"id": "HNO.70450891.eng.abstr-s1-t1",
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"Germany"
],
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10
]
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]
},
{
"id": "HNO.70450891.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"dog-bite"
],
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[
22,
30
]
],
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"db_id": "C0012984"
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},
{
"id": "HNO.70450891.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"dog-bite"
],
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22,
30
]
],
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},
{
"id": "HNO.70450891.eng.abstr-s1-t4",
"type": "umlsterm",
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"injuries"
],
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31,
39
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]
},
{
"id": "HNO.70450891.eng.abstr-s1-t5",
"type": "umlsterm",
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"face"
],
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47,
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]
],
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}
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},
{
"id": "HNO.70450891.eng.abstr-s1-t6",
"type": "umlsterm",
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"infants"
],
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}
]
},
{
"id": "HNO.70450891.eng.abstr-s2-t1",
"type": "umlsterm",
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"dogs"
],
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},
{
"id": "HNO.70450891.eng.abstr-s2-t2",
"type": "umlsterm",
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"animals"
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}
]
},
{
"id": "HNO.70450891.eng.abstr-s2-t3",
"type": "umlsterm",
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"cats"
],
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170,
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]
],
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}
]
},
{
"id": "HNO.70450891.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"horses"
],
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178,
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]
],
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}
]
},
{
"id": "HNO.70450891.eng.abstr-s2-t5",
"type": "umlsterm",
"text": [
"accidents"
],
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214,
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]
],
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},
{
"id": "HNO.70450891.eng.abstr-s3-t1",
"type": "umlsterm",
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"human"
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]
],
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}
]
},
{
"id": "HNO.70450891.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"bites"
],
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237,
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]
],
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}
]
},
{
"id": "HNO.70450891.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
"human bites"
],
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231,
242
]
],
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}
]
},
{
"id": "HNO.70450891.eng.abstr-s4-t1",
"type": "umlsterm",
"text": [
"nose"
],
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288,
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]
],
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"db_id": "C0028429"
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]
},
{
"id": "HNO.70450891.eng.abstr-s4-t2",
"type": "umlsterm",
"text": [
"auricles"
],
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301,
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]
],
"normalized": [
{
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"db_id": "C0013453"
}
]
},
{
"id": "HNO.70450891.eng.abstr-s5-t1",
"type": "umlsterm",
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"tissue"
],
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],
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]
},
{
"id": "HNO.70450891.eng.abstr-s5-t2",
"type": "umlsterm",
"text": [
"defects"
],
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],
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]
},
{
"id": "HNO.70450891.eng.abstr-s5-t3",
"type": "umlsterm",
"text": [
"amputations"
],
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]
],
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]
},
{
"id": "HNO.70450891.eng.abstr-s5-t4",
"type": "umlsterm",
"text": [
"nerve"
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]
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{
"id": "HNO.70450891.eng.abstr-s6-t1",
"type": "umlsterm",
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"antibiotic"
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]
},
{
"id": "HNO.70450891.eng.abstr-s6-t2",
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{
"id": "HNO.70450891.eng.abstr-s6-t3",
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{
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"neck"
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{
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"techniques"
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"transplantations"
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]
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{
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"flaps"
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{
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"wound"
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{
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"db_id": "C0040736"
}
]
}
] |
[] |
[] |
[
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{
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HNO.70450909.eng.abstr
|
HNO.70450909.eng.abstr
|
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"Distortion product otoacoustic emissions ( DPOAE ) are generated undoubtedly in the region of overlap between the two travelling waves of primaries f1 and f2 ( the \" primary \" generator ) . Since DPOAE lead to a psychoacoustic perception , it is suspected that the cochlear amplifier is additionally activated at place 2f1-f2 ( the \" secondary \" generator ) leading to a stimulus frequency emission ( SFOAE ) . In suppression experiments we demonstrated that a suppressor tone 25 Hz above the frequency of the postulated secondary generator alters DP-amplitude depending ( 1 ) on the DP-gram fine structure and ( 2 ) the sound pressure level of the suppressor ( -20 to 80 dB SPL ) . At a maximum of the fine structure , low suppressor levels ( 50 dB SPL ) reduced the DP-amplitude , whereas an increase occurred at a minimum . Intermediate suppressor levels ( 50-60 dB SPL ) always clamped the DP-amplitude and extinguished the DP-gram fine structure . Our results support the hypothesis that conventional DPOAE , which are measured in the external ear canal , are the result of an interference of the primary and secondary generator . Depending on the relative phase between the two emissions , a constructive and a destructive interference of the two signals results in an emission pattern which closely resembles the DP-gram fine structure . When the secondary generator is suppressed by intermediate suppressor levels , DPOAE amplitude depends only on the status of the cochlear amplifier near f2. These emissions we call \" single generator \" DPOAE ( sgDPOAE ) ."
],
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}
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[] |
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HNO.70450915.eng.abstr
|
HNO.70450915.eng.abstr
|
[
{
"id": "HNO.70450915.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Management of laryngeal carcinoma located at the anterior commissure remains controversial . Local control rates with radiotherapy or surgery are not as good as those seen after treatment of midcord lesions . The vertical partial laryngectomy with epiglottic reconstruction ( VPLER ) may be a more successful approach to such lesions . The charts of all patients treated for larynx carcinoma between 1991 and 1996 at the authors ' institutions were reviewed to identify those patients treated with VPLER as described by Sedlacek in 1965 , Kambic in 1976 and Tucker in 1979. Indications for performing surgery and outcome data of patients were collected and analyzed according to the indications for surgery , surgical technique , perioperative complications , oncological outcomes and functional results . Twelve patients were identified that had been treated with VPLER . Indications for surgery included five patients with local recurrences following endoscopic laser partial laryngectomies , four cases with previously untreated primary tumors at the anterior commissure ( T2 N0-2 M0), two with local recurrences following radiotherapy , and one with recurrence following frontolateral partial laryngectomy . There were no postoperative complications except for one laryngocutaneous fistula that required secondary repair . All patients were able to swallow at the tenth postoperative day . All had their tracheostomies closed after completion of wound healing , ( a mean of 17 days after surgery ) . Phonatory results were usually poor . Two local recurrences occurred during the follow-up period . However , both patients were salvaged with total laryngectomies and have since been free from disease . All other patients are alive and well . Our findings show that VPLER is an effective surgical approach for carcinoma at the anterior commissure of the larynx that cannot be adequately managed with transoral laser surgery or simple frontolateral partial laryngectomy . This study demonstrates that the procedure can be successfully applied to the treatment of local recurrences following initial raditherapy or surgery . No major complications occurred in our study ."
],
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0,
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]
}
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[] |
[] |
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] |
HNO.70450923.eng.abstr
|
HNO.70450923.eng.abstr
|
[
{
"id": "HNO.70450923.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In the planning of laser surgery for ENT operations , the specialist is often consulted by the anesthesiologist to predict possible intubation problems . Intubation problems in such operations can occur frequently due to the pathological findings present in the upper aerodigestive tract and the different constructions of laser-resistant endotracheal tubes . The aim of this study was to determine if a known predictive parameter could have a sufficient sensitivity and specificity to reliably predict possible intubation problems for ENT-related laser surgery . In a prospective study , 91 patients were included and the Mallampati-score modified by Samsoon and Young was analyzed and compared to a score describing the actual conditions of intubation . The results showed a significant correlation ( p 0.05 , Chi-Square test ) . However , the specificity was only 72% and the sensitivity of 60% was too low to be of practical use . The results were independent of the endotracheal tube used . Although use of the laser for ENT operations provides a special situation for the anesthesiologist , there is still no system that is sensitive and specific enough to be of practical use . This problem is demonstrated in a literature review ."
],
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0,
1238
]
]
}
] |
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] |
[] |
[] |
[
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HNO.70450927.eng.abstr
|
HNO.70450927.eng.abstr
|
[
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"id": "HNO.70450927.eng.abstr-passage-0",
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"Background : The problem of tinnitus in adults is reviewed systematically in nearly all standard otolaryngology reference works , whereas textbooks and monographs that focus on pediatric otorhinolaryngology or audiology and hearing in children and adolescents provide only little information concerning the epidemiology , etiology and therapy of tinnitus . The purpose of this study was to evaluate the psychosomatic aspects of chronic tinnitus in this younger age group . A rational diagnostic approach is discussed as to which diagnostic measures are necessary in the pediatric group for deciding which therapeutic option to chose . The therapeutic outcome of tinnitus counselling in non-severe cases and of parenteral lidocaine infusions in cases of a troublesome tinnitus is presented ."
],
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0,
790
]
]
}
] |
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[] |
[] |
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] |
HNO.70450933.eng.abstr
|
HNO.70450933.eng.abstr
|
[
{
"id": "HNO.70450933.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Benign esophageal strictures in the upper esophagus may be caused by systemic diseases . A rare reason for esophageal strictures are the mechanobullous disorders marked by blister formation following relatively minor trauma , e.g. epidermolysis bullosa . In this report we present a 63-year-old patient who had suffered from epidermolysis bullosa simplex since birth . The epicutaneous symptoms were no longer present but an esophageal stricture had developed . The stricture was treated by X-ray-controlled ballon dilation twice , with a functionally good result . We suggest managing a recurrence recidiv of stricture with balloon dilation to minimize trauma and prevent further lesions ."
],
"offsets": [
[
0,
690
]
]
}
] |
[
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17
]
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{
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"esophagus"
],
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]
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}
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{
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}
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{
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"esophageal strictures"
],
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7,
28
]
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{
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]
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{
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"minor"
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{
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]
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{
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],
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107,
128
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],
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{
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}
]
},
{
"id": "HNO.70450933.eng.abstr-s2-t6",
"type": "umlsterm",
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"epidermolysis bullosa"
],
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231,
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],
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{
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{
"id": "HNO.70450933.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"simplex"
],
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]
],
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]
},
{
"id": "HNO.70450933.eng.abstr-s3-t3",
"type": "umlsterm",
"text": [
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{
"id": "HNO.70450933.eng.abstr-s3-t4",
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],
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},
{
"id": "HNO.70450933.eng.abstr-s3-t5",
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],
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354
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{
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{
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{
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{
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{
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},
{
"id": "HNO.70450933.eng.abstr-s6-t4",
"type": "umlsterm",
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{
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"db_id": "C0004704"
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]
}
] |
[] |
[] |
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] |
HNO.70450967.eng.abstr
|
HNO.70450967.eng.abstr
|
[
{
"id": "HNO.70450967.eng.abstr-passage-0",
"type": "abstract",
"text": [
"We performed 25 fresh cadaver dissections to describe the anatomy of the superficial and deep circumflex iliac artery and the superficial inferior epigastric artery to determine how they could least to used as donor vessels for the free transfer of groin flaps and living iliac bone . With injection of ink the capillary region of these vessels was stained in ( iliac crest ) bone , the internal oblique muscle and skin of the groin and thigh . The superficial and deep circumflex iliac artery were shown to be the main supply vessels of the groin and thigh and could be found in 96%-100% of cases . The venous drainage of this region followed from a superficial system ( superficial circumflex iliac veins ) and a deep venous system ( Vv . comitantes accompaning arterial branches ) . Both venous systems could always be found . The superficial circumflex iliac artery was shown to only supply the skin and was the main donor vessel to the skin and soft tissue transplants . The deep circumflex iliac artery supplied the pelvic bone , the internal oblique muscle and a small constant area of skin above the iliac crest . Bone , muscle and bone , muscle and skin transplants could be obtained with this donor vessel , with enlargement of the skin area possible by combining two arterial branches combined in one transplant . With an average vessel diameter of 1.5 mm ( superficial circumflex iliac artery ) and 3 mm ( deep circumflex iliac artery ) both vessels could be used satisfactorily for microvascular transplantation . Different tissues including muscle , bone and skin could be obtained in adequate amounts to replace composite defects in the upper aerodigestive tract ."
],
"offsets": [
[
0,
1679
]
]
}
] |
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] |
[] |
[] |
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HNO.70450976.eng.abstr
|
HNO.70450976.eng.abstr
|
[
{
"id": "HNO.70450976.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The human temporal bone preparation is an acknowledged model for research of the physical processes affecting the outer ear canal and eardrum . Changes affecting the oscillation and resonance behavior of the tympanic membrane and ear canal between death and temporal bone preparation presently exist in only a few studies . Since the influence of age and physique , as well as the width of ear canal on the ear canal resonance may be important , we prepared two separate studies to analyze these questions . The goal of our first test series involved children and was devised to determine if changes in the outer auditory canal resonances differed according to age . In so doing , canal resonance was recorded with a real ear measurement system . Further , we recorded middle ear pressure , impedance of the tympanic membrane , ear canal volume , height , weight and surface of the body , head and ear size . We found a significant decrease in the resonance frequency of the outer ear which was age-dependent and was 2.75 kHz in the 7-year-old child . In a separate study we wanted to know if results found in the postmortem temporal bone reflected in vivo relationships . A tympanometer and real ear measurement system was used to test the resonance behavior of the auditory canal as well as the vibration of the eardrum in dependence on temperature and the time after death for 9 h . We then proved the absence of significant changes in the auditory canal and eardrum oscillation in this time period before possible postmortem changes occurred . Our findings show that the method of bone preservation after its preparation is decisive for the validity of measurements in the isolated human temporal bone ."
],
"offsets": [
[
0,
1707
]
]
}
] |
[
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],
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9
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],
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19,
23
]
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{
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] |
HNO.70450983.eng.abstr
|
HNO.70450983.eng.abstr
|
[
{
"id": "HNO.70450983.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In this retrospective study , oncologic and functional results of 24 patients treated for glomus jugulare tumor stages C and D are reported . The surgical approach used was a combined transmastoid-transcervical approach , which was modified according to individual tumor growth . As needed , this was combined with a transtemporal or retrosigmoid approach . Complete tumor removal resulted in a cure rate of 100% . Surgically induced cranial nerve palsies developed in 38% of the patients . In 54% of cases it was possible to retain middle ear function . Seven patients had incomplete tumor removal requiring postoperative irradiation , with tumor progression occurring in 2 patients . Radical tumor removal was modified by efforts to reduce mutilating resections . These results show that individually tailored and combined multidirectional surgical approaches can allow total tumor removal to be performed with lower morbidity ."
],
"offsets": [
[
0,
930
]
]
}
] |
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] |
[] |
[] |
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] |
HNO.70450990.eng.abstr
|
HNO.70450990.eng.abstr
|
[
{
"id": "HNO.70450990.eng.abstr-passage-0",
"type": "abstract",
"text": [
"We reviewed 192 patients who had been treated for chronic otitis media . All operations were carried out at the Department of Otolaryngology , University of Tuebingen . No patient had a previous ear operation and revision operations were excluded . The observation period varied from a minimum of 1 year to a maximum of 41/2 years . The ossicular chain was partially destroyed in 43 ears ( 22.4% ) . Ossiculoplasty was performed using autologous ossicles . An inens was used in 31 ears and a malleus in 12 cases . The overall failure rate was 20.8% . Most recurrent perforations were found in middle-aged patients . Children had only a 14% incidence of recurrent perforations . Fascia was the material associated with the highest failure rate ( 28.6% ) . After using perichondrium 6.8% of the cases had recurrent perforations , whereas the perichondrium-cartilage transplant was not successful in 4.8% . Overall , 62.7% of the patients were found to have an air-bone gap of 10 dB or less at 1.5 kHz 3-6 months after surgery . An air-bone gap of 20 dB or less was found in 91.2% of the patients . The main problem seen in the patients with chronic otitis media was not reconstruction of the ossicular chain but a lasting closure of the tympanic membrane . The perichondrium-cartilage transplant permitted the best results and is now recommended especially for patients with unfavorable middle ear conditions . A long-lasting closure of the tympanic membrane was also found in children ( =15 years of age ) . For this reason we also recommend an early operation in order to allow children to lead a normal life ."
],
"offsets": [
[
0,
1610
]
]
}
] |
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}
] |
HNO.70451018.eng.abstr
|
HNO.70451018.eng.abstr
|
[
{
"id": "HNO.70451018.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Variations of the clinical course of the internal carotid artery are reported with an incidence of 15-40% in the literature . They mainly arise from degenerative lesions leading to elongation , slight coiling , and kinking of the vessel . Besides that , a sigmoid tortuosity represents an occasional congenital anomaly . This article reports two cases of tortuosity of the internal carotid artery which resulted in impressions of the pharyngeal wall and minor globus syndromes . The possibility of false diagnoses is demonstrated . The etiology and clinical significance of these variations are discussed in detail ."
],
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[
0,
616
]
]
}
] |
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]
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]
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{
"id": "HNO.70451018.eng.abstr-s1-t5",
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{
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]
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{
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]
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{
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300,
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{
"id": "HNO.70451018.eng.abstr-s4-t5",
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{
"id": "HNO.70451018.eng.abstr-s4-t6",
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{
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]
}
] |
[] |
[] |
[
{
"id": "HNO.70451018.eng.abstr-s3-r1-t4.3-t2.1",
"type": "result_of",
"arg1_id": "HNO.70451018.eng.abstr-s3-t4",
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{
"id": "HNO.70451018.eng.abstr-s3-r2-t1.1-t4.2",
"type": "location_of",
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},
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},
{
"id": "HNO.70451018.eng.abstr-s3-r4-t2.1-t4.2",
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},
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{
"id": "HNO.70451018.eng.abstr-s3-r8-t2.1-t4.3",
"type": "result_of",
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{
"id": "HNO.70451018.eng.abstr-s3-r9-t4.2-t2.1",
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{
"id": "HNO.70451018.eng.abstr-s4-r1-t2.1-t5.1",
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},
{
"id": "HNO.70451018.eng.abstr-s4-r2-t5.1-t2.1",
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{
"id": "HNO.70451018.eng.abstr-s4-r3-t5.1-t2.1",
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"arg2_id": "HNO.70451018.eng.abstr-s6-t2",
"normalized": []
}
] |
HNO.70451022.eng.abstr
|
HNO.70451022.eng.abstr
|
[
{
"id": "HNO.70451022.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Angiofibromas are usually characterized by their occurences in adolescent males with a typical localization and involvement of the posterior nasal cavity and nasopharynx . Even the suspicion of an extranasopharyngeal angiofibroma or an angiofibroma in young children must be viewed in general with skepticism , although reports of angiofibromas with atypical localizations and manifestations in young children have appeared in the literature . Three cases of this fibro-vascular neoplasm with manifestations in the first decade of life and atypical localizations are presented : ( 1 ) an angiofibroma medial to the left lacrimal sac in a 15-month old boy , ( 2 ) a right paranasal localization in a 9-year-old boy and ( 3 ) an angiofibroma limited to the right sphenoid sinus in a 6-year old boy . In all three cases the neoplasm was resected via an endonasal , micro-endoscopic approach that avoided an external incision . According to the literature and based on our own experiences with typical histological findings in all three cases , the clinician has to be aware that the rare angiofibroma can occur in pre-adolescent children with atypical localizations . The endonasal surgical approach is without any doubt the least traumatic one and in selected cases allows resection of a circumscribed tumor considering functional and aesthetic aspects ."
],
"offsets": [
[
0,
1352
]
]
}
] |
[
{
"id": "HNO.70451022.eng.abstr-s1-t1",
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"text": [
"Angiofibromas"
],
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[
0,
13
]
],
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"db_name": "UMLS",
"db_id": "C0206731"
}
]
},
{
"id": "HNO.70451022.eng.abstr-s1-t2",
"type": "umlsterm",
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"adolescent"
],
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[
63,
73
]
],
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}
]
},
{
"id": "HNO.70451022.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"males"
],
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[
74,
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],
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"db_id": "C0024554"
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}
]
},
{
"id": "HNO.70451022.eng.abstr-s1-t4",
"type": "umlsterm",
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"posterior"
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},
{
"id": "HNO.70451022.eng.abstr-s1-t5",
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],
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]
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{
"id": "HNO.70451022.eng.abstr-s1-t6",
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},
{
"id": "HNO.70451022.eng.abstr-s2-t1",
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]
},
{
"id": "HNO.70451022.eng.abstr-s2-t2",
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] |
HNO.80460012.eng.abstr
|
HNO.80460012.eng.abstr
|
[
{
"id": "HNO.80460012.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In recent years the cochlear implant has become an established method for rehabilitation of bilateral sensory deafness in adults and children . Intracochlear multichannel stimulation with sophisticated speech coding strategies has proved to be reliable and safe enough for use in adults as well as young children ; thus , a few cochlear implant systems with different specifications are currently available . The differences in their hardware and software are discussed . Furthermore , the current indications for cochlear implants in patients whose hearing is severely impaired and important aspects of the preoperative evaluation are presented with special emphasis on dificult cases such as deformities , multihandicapped subjects and very young children . Our results after 12 years of experience and more than 700 implantations suggest that the most important prognostic factor is the duration of deafness ."
],
"offsets": [
[
0,
912
]
]
}
] |
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[] |
[] |
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HNO.80460027.eng.abstr
|
HNO.80460027.eng.abstr
|
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{
"id": "HNO.80460027.eng.abstr-passage-0",
"type": "abstract",
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"Development and short-term implantation results of the Tuebingen implantable hearing aid ( TI=Tuebingen implant ) have been presented [ 12 , 24 , 25 ] . The TI is designed for patients with sensorineural hearing loss due to a malfunction of the cochlear amplifier . This can be identified by the presence of positive recruitment and the absence of TEOAE ( transitory evoked otoacoustic emissions ) . The Tuebingen implant functions in two ways : it allows electronic amplification of the auditory signal and electromechanical signal transduction into a micromechanical vibratory stimulus . There are two paths by which vibratory stimulus reaches the cochlea : ( 1 ) directly through a perforation in the stapes foot plate into the perilymph or ( 2 ) via the ossicular chain ."
],
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0,
775
]
]
}
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}
] |
[] |
[] |
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] |
HNO.80460038.eng.abstr
|
HNO.80460038.eng.abstr
|
[
{
"id": "HNO.80460038.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The new technique of non-invasive magnetic resonance ( MR ) sialography was evaluated for normal and various pathologic conditions of the parotid gland . Ten volunteers and 15 patients with various symptomatic diseases of the parotid gland were tested in the present study . Diseases included pleomorphic adenoma , cystadenolymphoma , carcinoma ex pleomorphic adenoma , ductal carcinoma , adenoid cystic carcinoma , lymphoepithelial carcinoma , non-Hodgkin's lymphoma , sialolithiasis , sialadenitis , Heerfordt's syndrome and congenital duct ectasies . In addition to the usually performed T1 and T2 cross-sectional sequences a heavily weighted T2 sequence ( TR 3600 , TE 800 ) was performed and allowed depiction of a fluid-filled parotid duct . Results showed that the main parotid and primary branching ducts were depicted reliably in all normal cases and all patients , except one with sicca syndrome . Pathological conditions such as duct dilatations , duct strictures , obstructing duct calculus and irregular shapes and courses of the ductal system were demonstrable . While X-ray sialography obtained a higher resolution , only MR sialography was able to depict dilated ducts proximal from a complete obstruction , as well as all ductal cysts . Our findings show that MR sialography can be applied successfully to investigations of the parotid gland system . There have been no contraindications or complications to date because MR sialography is non-invasive . The technique will also allow the salivary ducts and lesions to be differentiated from the course of the facial nerve ."
],
"offsets": [
[
0,
1590
]
]
}
] |
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] |
[] |
[] |
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] |
HNO.80460044.eng.abstr
|
HNO.80460044.eng.abstr
|
[
{
"id": "HNO.80460044.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The precision of a new laser-guided navigation system ( the \" MKM \" ) was compared with the \" Viewing Wand \" mechanical navigation system . We describe the inherent deviations in each positioning system as well as errors caused by data acquisition and referencing between the CT data set used for navigation and the original object . Two thousand individual measurements were performed on geometric test models scanned by CT . The technical accuracy of the mechanical navigation system varied between 0.48 mm in the most favorable area of the working field and 1.8 mm in the more inaccurate areas . For the laser-guided system a precision of 0.27 mm was found for all areas of the working field . After referencing between the CT data set and the original object , the error of measurement increased in both navigation systems : i.e. , 0.83 mm for the Viewing Wand and 0.49 mm for the MKM system ."
],
"offsets": [
[
0,
897
]
]
}
] |
[
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],
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370
]
],
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{
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}
]
},
{
"id": "HNO.80460044.eng.abstr-s3-t2",
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"test"
],
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[
399,
403
]
],
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{
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}
]
},
{
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],
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]
],
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[] |
[] |
[
{
"id": "HNO.80460044.eng.abstr-s3-r1-t1.1-t2.1",
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HNO.80460050.eng.abstr
|
HNO.80460050.eng.abstr
|
[
{
"id": "HNO.80460050.eng.abstr-passage-0",
"type": "abstract",
"text": [
"The postoperative pain and stress experienced by tonsillectomy patients are often underestiminated . For this reason traditional methods of analgesia are frequently used but with an ineffective result . Our study involved an analysis of pain sensation with regard to postoperative analgesia after adult tonsillectomies . In all , 150 patients following tonsillectomy were treated with different methods of analgesia , which included Diclofenac monotherapy and combined treatment with Tramadol-retard and Naproxen . Postoperative sensations of pain were realized in a visual analogous painscore , with consideration given to individual experiences of subjective pain . In addition , circulatory and hemopoiesis parameters were controlled . Results showed that the postoperative analgesic effect of Diclofenac was significantly less than that of Tramadol-retard and Naproxen . Diclofenac monotherapy after tonsillectomy was only sufficient in cases involving an individual's low pain sensation . In cases with moderate or stronger pain the tonsillectomy patient requires an effective postoperative analgesia , as achieved with combined therapy using Tramadol retard and Naproxen . Aggravating side effects were not found in both schemes of analgesia ."
],
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0,
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}
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] |
[] |
[] |
[
{
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] |
HNO.80460056.eng.abstr
|
HNO.80460056.eng.abstr
|
[
{
"id": "HNO.80460056.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Acetylcholinesterase ( ACE ) inhibitor-induced angioedema is supposed to be an uncommon cause for oropharyngeal edema . Between January 1 , 1993 and February 1 , 1997 we treated 20 patients with edema of the oropharyngeal region that was not caused by infection or irradiation . The most common reason was an ACE-inhibitor-induced angioedema and occurred in 9 cases , all of whom required inpatient treatment . The medical management consisted of the administra- tion of intravenous ( i.v. ) glucocorticosteroids in all cases , H1-blockers in 6 cases , epinephrine by inhalation in one case and i.v. epinephrine in another case . Tracheostomy had to be performed in one patient . In our experience it is necessary to reconsider ACE inhibitor-induced angioedma in any case of an oropharyngeal edema . However , there is no reason for the routine application of epinephrine in these cases ."
],
"offsets": [
[
0,
888
]
]
}
] |
[
{
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"Acetylcholinesterase"
],
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[
0,
20
]
],
"normalized": [
{
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"db_id": "C0001044"
}
]
},
{
"id": "HNO.80460056.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"ACE"
],
"offsets": [
[
23,
26
]
],
"normalized": [
{
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},
{
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},
{
"db_name": "UMLS",
"db_id": "C0022709"
}
]
},
{
"id": "HNO.80460056.eng.abstr-s1-t3",
"type": "umlsterm",
"text": [
"angioedema"
],
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[
47,
57
]
],
"normalized": [
{
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"db_id": "C0002994"
}
]
},
{
"id": "HNO.80460056.eng.abstr-s1-t4",
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"text": [
"cause"
],
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[
88,
93
]
],
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{
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"db_id": "C0015127"
}
]
},
{
"id": "HNO.80460056.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"edema"
],
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[
112,
117
]
],
"normalized": [
{
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"db_id": "C0013604"
}
]
},
{
"id": "HNO.80460056.eng.abstr-s2-t1",
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"text": [
"patients"
],
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[
181,
189
]
],
"normalized": [
{
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]
},
{
"id": "HNO.80460056.eng.abstr-s2-t2",
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"text": [
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],
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[
195,
200
]
],
"normalized": [
{
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}
]
},
{
"id": "HNO.80460056.eng.abstr-s2-t3",
"type": "umlsterm",
"text": [
"infection"
],
"offsets": [
[
252,
261
]
],
"normalized": [
{
"db_name": "UMLS",
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] |
[] |
[] |
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] |
HNO.80460066.eng.abstr
|
HNO.80460066.eng.abstr
|
[
{
"id": "HNO.80460066.eng.abstr-passage-0",
"type": "abstract",
"text": [
"We report the rare development of a myoepithelial carcinoma in a pleomorphic adenoma involving the minor salivary glands in the buccal mucosa of a 78-year-old female . Tumor presented as a small asymptomatic left buccal mass . The initial dominant component of the neoplasm was a pleomorphic adenoma , while the minor component was a myoepithelial carcinoma . Recurrences of tumor after 2 and then 5 years were excised . Histopathological examination of the last tissue removed showed a pure myoepithelial carcinoma of the minor salivary glands without evidence for a pleomorphic adenoma . The clinical features , therapy , diagnosis , histopathology and literature are reviewed ."
],
"offsets": [
[
0,
680
]
]
}
] |
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{
"id": "HNO.80460066.eng.abstr-s1-t1",
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"development"
],
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19,
30
]
],
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}
]
},
{
"id": "HNO.80460066.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"carcinoma"
],
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50,
59
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"db_id": "C0007097"
}
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{
"id": "HNO.80460066.eng.abstr-s1-t3",
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"adenoma"
],
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77,
84
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},
{
"id": "HNO.80460066.eng.abstr-s1-t4",
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"minor"
],
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99,
104
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"db_id": "C0026193"
}
]
},
{
"id": "HNO.80460066.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"mucosa"
],
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[
135,
141
]
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"db_id": "C0026724"
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},
{
"id": "HNO.80460066.eng.abstr-s1-t6",
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"female"
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165
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"db_id": "C0086287"
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"db_name": "UMLS",
"db_id": "C0015780"
}
]
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{
"id": "HNO.80460066.eng.abstr-s1-t7",
"type": "umlsterm",
"text": [
"pleomorphic adenoma"
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[
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],
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"db_id": "C0026277"
}
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},
{
"id": "HNO.80460066.eng.abstr-s1-t8",
"type": "umlsterm",
"text": [
"salivary glands"
],
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[
105,
120
]
],
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"db_id": "C0036098"
}
]
},
{
"id": "HNO.80460066.eng.abstr-s1-t9",
"type": "umlsterm",
"text": [
"buccal mucosa"
],
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[
128,
141
]
],
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{
"db_name": "UMLS",
"db_id": "C0026639"
}
]
},
{
"id": "HNO.80460066.eng.abstr-s1-t10",
"type": "umlsterm",
"text": [
"minor salivary glands"
],
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[
99,
120
]
],
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"db_id": "C0036099"
}
]
},
{
"id": "HNO.80460066.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"Tumor"
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[
168,
173
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},
{
"id": "HNO.80460066.eng.abstr-s3-t1",
"type": "umlsterm",
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"neoplasm"
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{
"id": "HNO.80460066.eng.abstr-s3-t2",
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"adenoma"
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{
"id": "HNO.80460066.eng.abstr-s3-t3",
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{
"id": "HNO.80460066.eng.abstr-s3-t4",
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"carcinoma"
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{
"id": "HNO.80460066.eng.abstr-s3-t5",
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{
"id": "HNO.80460066.eng.abstr-s4-t1",
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"id": "HNO.80460066.eng.abstr-s5-t5",
"type": "umlsterm",
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"id": "HNO.80460066.eng.abstr-s5-t6",
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"db_id": "C0023866"
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}
] |
[] |
[] |
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HNO.80460102.eng.abstr
|
HNO.80460102.eng.abstr
|
[
{
"id": "HNO.80460102.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Recurrent aphthae ( or aphthoses ) are the most frequent inflammatory lesions of the oral mucosa . Aphthae can clearly be defined , but may also be barely discernible from aphthoid erosions and ulcers of heterogeneous origin . Although a subject of molecular research , the etiopathogenesis of oral aphthoses is still unknown . However , the clinical differentiation of a \" benign \" type of aphthosis from a \" pernicious \" one , such as Behçet's disease ( BD ) , is a diagnostic matter of great significance . BD has been found clinically in increasing numbers in central Europe and represents an ( auto- ) hyperimmune multisystem life-threatening vasculitis . In this disorder possible damage can occur to many visceral organs and/or the cerebrospinal system . The prognosis of BD may depend on the changing involvement of very different organs , as well as the early recognition of the disease per se . The most prominent feature is a multilesional aphthous stomatitis that is almost never absent during acute episodes of BD . Hence , the occurrence of this peculiar type of aphthosis strongly indicates an active BD . The plethora of other aphthoid lesions can be challenging to the diagnostic competence of all physicians and may confuse the correct recognition of the severity of the disease present . This review particularly details the wide range of diagnostic , therapeutic and prognostic aspects of the various oral aphthoses ."
],
"offsets": [
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0,
1437
]
]
}
] |
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] |
[] |
[] |
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}
] |
HNO.80460121.eng.abstr
|
HNO.80460121.eng.abstr
|
[
{
"id": "HNO.80460121.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A fully implantable hearing aid consists of a sound receptor ( microphone ) , an electronic amplifier including active audio-signal processing , an electromechanical transducer ( actuator ) for stimulating the ear by vibration , and an energy source . The energy source may be either a primary cell or a rechargeable ( secondary ) cell . As the energy requirements of an implantable hearing aid are dependent on the operating principle of the actuator , the operating principles of electromagnetic and piezoelectric transducers were examined with respect to their relative power consumption . The analysis showed that the energy requirements of an implantable hearing aid are significantly increased when an electromagnetic transducer is used . The power consumption of a piezoelectric transducer was found to be less than that of the electronic components alone . The energy needed to run a fully implantable hearing aid under these conditions would be 38 mWH per day . Primary cells cannot provide the energy needed for a minimum operation time of 5 years ( 70 WH ) , and therefore rechargeable cells must be used . A theoretical appraisal was carried out on nickel-cadmium , nickel-metal hydride , and lithium-ion cells to determine their suitability as well as to assess the risks associated with their use in an implant . Safety measures were drawn up from the results . Ni-MH cells were found to be the most suitable for use as an energy source for implantable hearing-aids because they are more robust than Li ion cells and their storage capacity is double that of Ni-Cd cells of similar size ."
],
"offsets": [
[
0,
1601
]
]
}
] |
[
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"hearing"
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27
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{
"id": "HNO.80460121.eng.abstr-s1-t2",
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"aid"
],
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[
28,
31
]
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},
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}
]
},
{
"id": "HNO.80460121.eng.abstr-s1-t3",
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"sound"
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},
{
"id": "HNO.80460121.eng.abstr-s1-t4",
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"electronic"
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}
]
},
{
"id": "HNO.80460121.eng.abstr-s1-t5",
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"amplifier"
],
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[
92,
101
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}
]
},
{
"id": "HNO.80460121.eng.abstr-s1-t6",
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"transducer"
],
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]
},
{
"id": "HNO.80460121.eng.abstr-s1-t7",
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"ear"
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[
210,
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]
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}
]
},
{
"id": "HNO.80460121.eng.abstr-s1-t8",
"type": "umlsterm",
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"vibration"
],
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[
217,
226
]
],
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}
]
},
{
"id": "HNO.80460121.eng.abstr-s1-t9",
"type": "umlsterm",
"text": [
"hearing aid"
],
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[
20,
31
]
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]
},
{
"id": "HNO.80460121.eng.abstr-s1-t10",
"type": "umlsterm",
"text": [
"energy source"
],
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[
236,
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]
},
{
"id": "HNO.80460121.eng.abstr-s2-t1",
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"cell"
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]
},
{
"id": "HNO.80460121.eng.abstr-s2-t2",
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"secondary"
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]
},
{
"id": "HNO.80460121.eng.abstr-s2-t3",
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]
},
{
"id": "HNO.80460121.eng.abstr-s2-t4",
"type": "umlsterm",
"text": [
"energy source"
],
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[
256,
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},
{
"id": "HNO.80460121.eng.abstr-s3-t1",
"type": "umlsterm",
"text": [
"hearing"
],
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]
},
{
"id": "HNO.80460121.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
"aid"
],
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]
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] |
[] |
[] |
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},
{
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}
] |
HNO.80460129.eng.abstr
|
HNO.80460129.eng.abstr
|
[
{
"id": "HNO.80460129.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Besides a knowledge of material properties geometric properties are needed to investigate the mechanical behavior of the human eardrum . Although the geometry of the eardrum has been examined methodically , its composition has been described in the literature . The true surface geometry of a cadaver specimen of the human eardrum was examined under a laser-scanning microscope . Forty points ( 85 parameters ) depicted the surface of this cadaver specimen and formed the basis for a finite shell model . Furthermore , the coupling with the malleus and its suspension was simulated . Additional geometric and material parameters were chosen from the available literature . Both static behavior and the influence of a parameter variation to modal behavior of the finite element model were tested . ANSYS 5.1 software was used for this study ."
],
"offsets": [
[
0,
841
]
]
}
] |
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{
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127,
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}
] |
[] |
[] |
[
{
"id": "HNO.80460129.eng.abstr-s1-r1-t3.1-t2.1",
"type": "exhibits",
"arg1_id": "HNO.80460129.eng.abstr-s7-t3",
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"id": "HNO.80460129.eng.abstr-s3-r1-t1.1-t2.1",
"type": "interacts_with",
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},
{
"id": "HNO.80460129.eng.abstr-s3-r2-t2.1-t1.1",
"type": "part_of",
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},
{
"id": "HNO.80460129.eng.abstr-s3-r3-t2.1-t1.1",
"type": "interacts_with",
"arg1_id": "HNO.80460129.eng.abstr-s7-t2",
"arg2_id": "HNO.80460129.eng.abstr-s8-t1",
"normalized": []
},
{
"id": "HNO.80460129.eng.abstr-s7-r1-t4.1-t2.1",
"type": "affects",
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"arg2_id": "HNO.80460129.eng.abstr-s7-t2",
"normalized": []
}
] |
HNO.80460135.eng.abstr
|
HNO.80460135.eng.abstr
|
[
{
"id": "HNO.80460135.eng.abstr-passage-0",
"type": "abstract",
"text": [
"In a series of 9 patients with advanced carcinomas of the posterior wall of the hypopharynx ( 2 patients with T2 tumors and 7 patients with T4 disease ) , we tried to preserve the larynx with surgical therapy . The concept of laryngeal preservation consisted of lateral pharyngotomy with free flap reconstruction of the defect created by the tumor resection . A recommendation for surgery was given to each patient with a neoplasm in the posterior pharyngeal wall and tumor extension > 6 cm in diameter . The maximum tumor diameters ranged between 6.5 cm and 12.5 cm . Reconstruction was performed in 8 cases with radial forearm flaps while a jejunal transplant was used in one case due to the extension of tumor . During each surgical procedure an attempt was made to preserve the superior laryngeal nerves and transplants were adapted exactly to the resection defects . Seven patients achieved oral swallowing within three months of surgery , while one patient needed four months to swallow orally . One patient had persistent aspiration and still needs a percutaneous gastrostomy . Six patients were decannulated successfully , so that laryngectomy was avoided during postoperative follow-up . These results show that surgical therapy of advanced carcinoma of the posterior wall of the hypopharynx is possible with preservation of the larynx . Additionally , functional outcome after treatment of these patients with free flap reconstruction is comparable to other treatment modalities , such as radiochemotherapy ."
],
"offsets": [
[
0,
1518
]
]
}
] |
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},
{
"id": "HNO.80460135.eng.abstr-s1-t2",
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"carcinomas"
],
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40,
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],
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}
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{
"id": "HNO.80460135.eng.abstr-s1-t3",
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"posterior"
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{
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{
"id": "HNO.80460135.eng.abstr-s1-t9",
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"larynx"
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[] |
[] |
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] |
HNO.80460140.eng.abstr
|
HNO.80460140.eng.abstr
|
[
{
"id": "HNO.80460140.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Forty-one patients with locally advanced hypopharyngeal carcinomas were followed for at least 3 years ( median , 60 months ) after simultaneous radiochemotherapy . Conventionally fractionated radiotherapy was administered as 5x2 Gy/week to a total dose of 30 Gy within 3 weeks . From the fourth week an accelerated hyperfractionated schedule was used as 2x1.4 Gy/day five days weekly given exclusively to the first order target volume of macroscopic tumor ( adding up to a total dose of 72 Gy in six weeks ) . The second and third order target volumes received conventional fractionation only to 60 Gy and 50 Gy , respectively . The moderate acceleration of the concomitant boost scheme in the second half was counterbalanced during the first week by the introduction of a 5-fluorouracil bolus of 350 mg/M2 with 200 mg/M2 folinic acid and a subsequent continuous infusion using the same dose each 24 h for 5 days . Additionally , a Mitomycin-C bolus of 10 mg/M2 was infused at the fifth day and on the first day of the sixth week . Six weeks after treatment the patients were restaged . In cases with residual carcinoma salvage surgery was performed ( 11 patients ) . Late effects of therapy were analyzed according to the Lent-Soma index and life quality according to the European Organisation for Research and Treatment of Cancer-Modul . Late effects of treatment were tolerable and were controlled locally . The 3-year-survival rate was 39% , with a local-regional recurrence-free control rate of 71% . Fifty-two percent of all cases of death were caused by distant metastases , secondary carcinomas or other diseases not related to tumor recurrence . The poor prognosis of hypopharyngeal carcinomas despite acceptable local tumor control may be due to specific biological factors present in affected patients ."
],
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[
0,
1814
]
]
}
] |
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] |
[] |
[] |
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] |
HNO.80460146.eng.abstr
|
HNO.80460146.eng.abstr
|
[
{
"id": "HNO.80460146.eng.abstr-passage-0",
"type": "abstract",
"text": [
"A normal ciliary beat frequency of ciliated cells is necessary for the mucociliary clearance of the nose and paranasal sinuses . An in vitro investigation was performed to eval-uate the influence of topical corticosteroids and antihistamines on the ciliary beat frequency of human nasal mucosa . The nasal sprays examined contained the corticosteroids budesonide or fluticasone propionate and the topical antihistamines azelastine or levocabastine . All tests were performed on cell cultures of human nasal mucosa during constant conditions . Three of the four nasal sprays tested contained benzalkonium chloride as preservative . An irreversible cessation of ciliary movement was observed in all cells exposed to nasal sprays containing benzalkonium chloride in a 50 per cent solution . The nasal spray containing budesonide was benzalkonium chloride-free and caused minor but fully reversible decreases in ciliary beat frequency after 20 min . As benzalkonium chloride can cause complete standstill of ciliary beat frequency in vitro in human nasal mucosa , we recommend that this preservative should not be used anymore in topical nasal medications ."
],
"offsets": [
[
0,
1153
]
]
}
] |
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] |
[] |
[] |
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}
] |
HNO.80460152.eng.abstr
|
HNO.80460152.eng.abstr
|
[
{
"id": "HNO.80460152.eng.abstr-passage-0",
"type": "abstract",
"text": [
"Background : Indirect traumatic optic neuropathy represents a severe , potential vision-threatening disease process that requires close interdisciplinary cooperation for treatment . In general , any therapy has been dis-cussed controversially in the literature . Based upon experiences with spinal cord trauma , high-dose steroid therapy is recommended initially to minimize secondary consequences following orbital trauma . The usefulness of surgical decompression of the optic nerve has been confirmed in several studies but is still not recommended in principle ."
],
"offsets": [
[
0,
566
]
]
}
] |
[
{
"id": "HNO.80460152.eng.abstr-s1-t1",
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"text": [
"optic"
],
"offsets": [
[
32,
37
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0029144"
}
]
},
{
"id": "HNO.80460152.eng.abstr-s1-t2",
"type": "umlsterm",
"text": [
"disease"
],
"offsets": [
[
100,
107
]
],
"normalized": [
{
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"db_id": "C0012634"
}
]
},
{
"id": "HNO.80460152.eng.abstr-s1-t3",
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"treatment"
],
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[
170,
179
]
],
"normalized": [
{
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"db_id": "C0087111"
},
{
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"db_id": "C0039798"
}
]
},
{
"id": "HNO.80460152.eng.abstr-s1-t4",
"type": "umlsterm",
"text": [
"optic neuropathy"
],
"offsets": [
[
32,
48
]
],
"normalized": [
{
"db_name": "UMLS",
"db_id": "C0029132"
}
]
},
{
"id": "HNO.80460152.eng.abstr-s1-t5",
"type": "umlsterm",
"text": [
"traumatic optic neuropathy"
],
"offsets": [
[
22,
48
]
],
"normalized": [
{
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"db_id": "C0161398"
}
]
},
{
"id": "HNO.80460152.eng.abstr-s2-t1",
"type": "umlsterm",
"text": [
"therapy"
],
"offsets": [
[
199,
206
]
],
"normalized": [
{
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"db_id": "C0087111"
},
{
"db_name": "UMLS",
"db_id": "C0039798"
}
]
},
{
"id": "HNO.80460152.eng.abstr-s2-t2",
"type": "umlsterm",
"text": [
"literature"
],
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[
250,
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]
],
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{
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}
]
},
{
"id": "HNO.80460152.eng.abstr-s3-t1",
"type": "umlsterm",
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"trauma"
],
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[
303,
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]
],
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]
},
{
"id": "HNO.80460152.eng.abstr-s3-t2",
"type": "umlsterm",
"text": [
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],
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[
322,
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]
],
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}
]
},
{
"id": "HNO.80460152.eng.abstr-s3-t3",
"type": "umlsterm",
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"therapy"
],
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330,
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],
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},
{
"id": "HNO.80460152.eng.abstr-s3-t4",
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"secondary"
],
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375,
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],
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},
{
"id": "HNO.80460152.eng.abstr-s3-t5",
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]
},
{
"id": "HNO.80460152.eng.abstr-s3-t6",
"type": "umlsterm",
"text": [
"spinal cord"
],
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]
],
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{
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{
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{
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},
{
"id": "HNO.80460152.eng.abstr-s3-t7",
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],
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291,
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},
{
"id": "HNO.80460152.eng.abstr-s4-t1",
"type": "umlsterm",
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"surgical"
],
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},
{
"id": "HNO.80460152.eng.abstr-s4-t2",
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],
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]
],
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]
},
{
"id": "HNO.80460152.eng.abstr-s4-t3",
"type": "umlsterm",
"text": [
"nerve"
],
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479,
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]
],
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{
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]
},
{
"id": "HNO.80460152.eng.abstr-s4-t4",
"type": "umlsterm",
"text": [
"surgical decompression"
],
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[
443,
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]
],
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]
},
{
"id": "HNO.80460152.eng.abstr-s4-t5",
"type": "umlsterm",
"text": [
"optic nerve"
],
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[
473,
484
]
],
"normalized": [
{
"db_name": "UMLS",
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},
{
"db_name": "UMLS",
"db_id": "C0029130"
},
{
"db_name": "UMLS",
"db_id": "C0029132"
}
]
}
] |
[] |
[] |
[
{
"id": "HNO.80460152.eng.abstr-s1-r1-t5.1-t2.1",
"type": "result_of",
"arg1_id": "HNO.80460152.eng.abstr-s4-t5",
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},
{
"id": "HNO.80460152.eng.abstr-s1-r2-t3.1-t1.1",
"type": "issue_in",
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},
{
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},
{
"id": "HNO.80460152.eng.abstr-s1-r4-t3.2-t1.1",
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},
{
"id": "HNO.80460152.eng.abstr-s1-r5-t5.1-t3.1",
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},
{
"id": "HNO.80460152.eng.abstr-s1-r6-t2.1-t3.1",
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},
{
"id": "HNO.80460152.eng.abstr-s1-r7-t5.1-t3.1",
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},
{
"id": "HNO.80460152.eng.abstr-s1-r8-t2.1-t5.1",
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},
{
"id": "HNO.80460152.eng.abstr-s1-r9-t3.1-t1.1",
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},
{
"id": "HNO.80460152.eng.abstr-s1-r10-t5.1-t1.1",
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},
{
"id": "HNO.80460152.eng.abstr-s1-r11-t3.1-t5.1",
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"arg1_id": "HNO.80460152.eng.abstr-s4-t3",
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},
{
"id": "HNO.80460152.eng.abstr-s1-r12-t3.1-t5.1",
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},
{
"id": "HNO.80460152.eng.abstr-s1-r13-t2.1-t1.1",
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"arg2_id": "HNO.80460152.eng.abstr-s4-t1",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s3-r1-t2.1-t1.1",
"type": "causes",
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"arg2_id": "HNO.80460152.eng.abstr-s4-t1",
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},
{
"id": "HNO.80460152.eng.abstr-s3-r2-t4.2-t6.1",
"type": "associated_with",
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"arg2_id": "HNO.80460152.eng.abstr-s3-t6",
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},
{
"id": "HNO.80460152.eng.abstr-s3-r3-t6.1-t1.1",
"type": "location_of",
"arg1_id": "HNO.80460152.eng.abstr-s3-t6",
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"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s3-r4-t4.2-t5.1",
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},
{
"id": "HNO.80460152.eng.abstr-s3-r5-t3.1-t6.3",
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},
{
"id": "HNO.80460152.eng.abstr-s3-r6-t4.2-t3.1",
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},
{
"id": "HNO.80460152.eng.abstr-s3-r7-t6.1-t4.2",
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},
{
"id": "HNO.80460152.eng.abstr-s3-r8-t6.1-t5.1",
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},
{
"id": "HNO.80460152.eng.abstr-s3-r9-t2.1-t3.1",
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},
{
"id": "HNO.80460152.eng.abstr-s3-r10-t4.2-t1.1",
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},
{
"id": "HNO.80460152.eng.abstr-s3-r11-t2.1-t6.1",
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},
{
"id": "HNO.80460152.eng.abstr-s3-r12-t3.1-t6.1",
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"arg1_id": "HNO.80460152.eng.abstr-s4-t3",
"arg2_id": "HNO.80460152.eng.abstr-s3-t6",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s3-r13-t3.1-t4.2",
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"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s3-r14-t1.1-t6.3",
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"arg2_id": "HNO.80460152.eng.abstr-s3-t6",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s3-r15-t3.1-t5.1",
"type": "associated_with",
"arg1_id": "HNO.80460152.eng.abstr-s4-t3",
"arg2_id": "HNO.80460152.eng.abstr-s4-t5",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s3-r16-t2.1-t6.3",
"type": "causes",
"arg1_id": "HNO.80460152.eng.abstr-s4-t2",
"arg2_id": "HNO.80460152.eng.abstr-s3-t6",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s3-r17-t2.1-t4.2",
"type": "causes",
"arg1_id": "HNO.80460152.eng.abstr-s4-t2",
"arg2_id": "HNO.80460152.eng.abstr-s3-t4",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s3-r19-t2.1-t6.3",
"type": "affects",
"arg1_id": "HNO.80460152.eng.abstr-s4-t2",
"arg2_id": "HNO.80460152.eng.abstr-s3-t6",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s3-r20-t2.1-t5.1",
"type": "causes",
"arg1_id": "HNO.80460152.eng.abstr-s4-t2",
"arg2_id": "HNO.80460152.eng.abstr-s4-t5",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s3-r21-t6.1-t3.1",
"type": "location_of",
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"arg2_id": "HNO.80460152.eng.abstr-s4-t3",
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},
{
"id": "HNO.80460152.eng.abstr-s3-r22-t1.1-t4.2",
"type": "associated_with",
"arg1_id": "HNO.80460152.eng.abstr-s4-t1",
"arg2_id": "HNO.80460152.eng.abstr-s3-t4",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s3-r23-t3.1-t1.1",
"type": "associated_with",
"arg1_id": "HNO.80460152.eng.abstr-s4-t3",
"arg2_id": "HNO.80460152.eng.abstr-s4-t1",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s3-r24-t1.1-t6.1",
"type": "associated_with",
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"arg2_id": "HNO.80460152.eng.abstr-s3-t6",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s3-r25-t1.1-t5.1",
"type": "associated_with",
"arg1_id": "HNO.80460152.eng.abstr-s4-t1",
"arg2_id": "HNO.80460152.eng.abstr-s4-t5",
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},
{
"id": "HNO.80460152.eng.abstr-s3-r26-t4.2-t6.3",
"type": "associated_with",
"arg1_id": "HNO.80460152.eng.abstr-s3-t4",
"arg2_id": "HNO.80460152.eng.abstr-s3-t6",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s3-r27-t6.1-t2.1",
"type": "produces",
"arg1_id": "HNO.80460152.eng.abstr-s3-t6",
"arg2_id": "HNO.80460152.eng.abstr-s4-t2",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s3-r28-t1.1-t3.1",
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},
{
"id": "HNO.80460152.eng.abstr-s4-r1-t3.1-t1.1",
"type": "issue_in",
"arg1_id": "HNO.80460152.eng.abstr-s4-t3",
"arg2_id": "HNO.80460152.eng.abstr-s4-t1",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s4-r2-t1.1-t3.1",
"type": "result_of",
"arg1_id": "HNO.80460152.eng.abstr-s4-t1",
"arg2_id": "HNO.80460152.eng.abstr-s4-t3",
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},
{
"id": "HNO.80460152.eng.abstr-s4-r3-t3.1-t5.3",
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},
{
"id": "HNO.80460152.eng.abstr-s4-r4-t5.1-t3.1",
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"arg2_id": "HNO.80460152.eng.abstr-s4-t3",
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},
{
"id": "HNO.80460152.eng.abstr-s4-r5-t3.1-t5.3",
"type": "result_of",
"arg1_id": "HNO.80460152.eng.abstr-s4-t3",
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},
{
"id": "HNO.80460152.eng.abstr-s4-r6-t5.1-t1.1",
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},
{
"id": "HNO.80460152.eng.abstr-s4-r7-t5.3-t1.1",
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},
{
"id": "HNO.80460152.eng.abstr-s4-r8-t3.1-t5.1",
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"arg2_id": "HNO.80460152.eng.abstr-s4-t5",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s4-r9-t5.1-t3.1",
"type": "location_of",
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"arg2_id": "HNO.80460152.eng.abstr-s4-t3",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s4-r12-t5.1-t3.1",
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"arg2_id": "HNO.80460152.eng.abstr-s4-t3",
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},
{
"id": "HNO.80460152.eng.abstr-s4-r13-t3.1-t1.1",
"type": "method_of",
"arg1_id": "HNO.80460152.eng.abstr-s4-t3",
"arg2_id": "HNO.80460152.eng.abstr-s4-t1",
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},
{
"id": "HNO.80460152.eng.abstr-s4-r14-t5.3-t3.1",
"type": "associated_with",
"arg1_id": "HNO.80460152.eng.abstr-s4-t5",
"arg2_id": "HNO.80460152.eng.abstr-s4-t3",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s4-r16-t3.1-t5.1",
"type": "result_of",
"arg1_id": "HNO.80460152.eng.abstr-s4-t3",
"arg2_id": "HNO.80460152.eng.abstr-s4-t5",
"normalized": []
},
{
"id": "HNO.80460152.eng.abstr-s4-r17-t5.3-t3.1",
"type": "result_of",
"arg1_id": "HNO.80460152.eng.abstr-s4-t5",
"arg2_id": "HNO.80460152.eng.abstr-s4-t3",
"normalized": []
}
] |
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