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Mult-iomic integrated curvature study on pan-cancer genomic data
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bioinformatics
|
Charge transfer of unconfined regions in quasi-periodic quantum wells : DNA nanostructure study
|
biophysics
|
Model biomolecular condensates have heterogeneous structure quantitatively dependent on the interaction profile of their constituent macromolecules
|
biophysics
|
NADK upregulation is an essential metabolic adaptation that enables breast cancer metastatic colonization
|
cancer biology
|
AMP-kinase mediates adaptation of glioblastoma cells to conditions of the tumour microenvironment
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cancer biology
|
CRISPR-induced exon skipping of β-catenin reveals tumorigenic mutants driving distinct subtypes of liver cancer
|
cancer biology
|
S6K1 phosphorylates Cdk1 and MSH6 to regulate DNA repair.
|
cancer biology
|
LAMC2 marks a tumor-initiating cell population with an aggressive signature in pancreatic cancer
|
cancer biology
|
Integrative single cell and spatial transcriptomic analysis reveal reciprocal microglia - plasma cell crosstalk in the mouse brain during chronic Trypanosoma brucei infection
|
pathology
|
Leaf nitrogen does not explain changes in soybean radiation-use efficiency in vegetative and early reproductive stages
|
physiology
|
Deep Phenotyping and Lifetime Trajectories Reveal Limited Effects of Longevity Regulators on the Aging Process in C57BL/6J Mice
|
physiology
|
Establishing a reproducible approach for the controllable deposition and maintenance of plants cells with 3D bioprinting
|
plant biology
|
Complex developmental and transcriptional dynamics underlie pollinator-driven evolutionary transitions in nectar spur morphology in Aquilegia (columbine)
|
plant biology
|
Polymer nanoparticles pass the plant interface
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plant biology
|
Animal-reliance bias in publishing is a potential barrier to scientific progress
|
scientific communication and education
|
Improving patient survival by direct targeting of chimeric protein-protein interaction networks
|
systems biology
|
Protein synthesis inhibition and loss of homeostatic functions in astrocytes from an Alzheimer's disease mouse model: a role for ER-mitochondria interaction.
|
neuroscience
|
The general anesthetic isoflurane inhibits calcium activity in cerebrovascular endothelial cells and disrupts vascular tone
|
neuroscience
|
Subjective cognitive decline predicts lower cingulo-opercular network functional connectivity in individuals with lower neurite density in the forceps minor
|
neuroscience
|
Pharmacological manipulations of physiological arousal and sleep-like slow waves modulate sustained attention
|
neuroscience
|
Synthetic torpor triggers a neuroprotective and regulated mechanism in the rat brain, leading to the reversibility of Tau protein hyperphosphorylation.
|
neuroscience
|
A Spinal Circuit That Transmits Innocuous Cool Sensations
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neuroscience
|
Sex-specific effects of chronic paternal stress on offspring development are partially mediated via mothers.
|
neuroscience
|
Intact maternal buffering of stress response in infant rats despite altered responsivity towards maternal olfactory cues in the valproic acid model of autism-like behavior
|
neuroscience
|
Microglial TNFα orchestrates brain phosphorylation during the sleep period and controls homeostatic sleep.
|
neuroscience
|
Sex-specific role of the circadian transcription factor NPAS2 in opioid tolerance, withdrawal, and analgesia
|
neuroscience
|
Robust Estimation of 1/f Activity Improves Oscillatory Burst Detection
|
neuroscience
|
Single-cell Transcriptomic Atlas of the Human Substantia Nigra in Parkinson's Disease
|
neuroscience
|
Enhanced short-wavelength sensitivity in the blue-tongued skink,Tiliqua rugosa
|
neuroscience
|
Resting-state connectivity underlying cognitive controls association with perspective taking in callous-unemotional traits
|
neuroscience
|
The role of optogenetic stimulations of parvalbumin-positive interneurons in the prefrontal cortex and the ventral hippocampus on an acute MK801 model of schizophrenia-like cognitive inflexibility
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neuroscience
|
TNFR2 costimulation differentially impacts regulatory and conventional CD4+ T-cell metabolism
|
immunology
|
Rapid differentiation of regulatory CD4+ T cells in the infarcted myocardium blunts in situ inflammation
|
immunology
|
Multiple alr genes exhibit allorecognition-associated variation in the colonial cnidarian Hydractinia
|
immunology
|
A gut commensal protozoa remotely shapes a lung niche for asthma-promoting eosinophils.
|
immunology
|
Phase Separation of a Nodulin Sec14-like protein Maintains Auxin Efflux Carrier Polarity at Arabidopsis Plasma Membranes
|
cell biology
|
Exosomally targeting microRNA23a ameliorates microvascular endothelial barrier dysfunction following rickettsial infection
|
cell biology
|
Development of a Novel Microfluidic Co-culture model to study Organoid Vascularization
|
cell biology
|
Lis1-dynein drives corona compaction and error-correction at kinetochores
|
cell biology
|
Paf1C denoises transcription and growth patterns to achieve organ shape reproducibility
|
developmental biology
|
High-resolution Ribosome Profiling Reveals Translational Selectivity for Transcripts in Bovine Preimplantation Embryo Development
|
developmental biology
|
Utilisation of Oxford Nanopore sequencing to generate six complete gastropod mitochondrial genomes as part of a biodiversity curriculum
|
ecology
|
qad: An R-package to detect asymmetric and directed dependence in bivariate samples
|
ecology
|
Novel Methods for Multi-ancestry Polygenic Prediction and their Evaluations in 3.7 Million Individuals of Diverse Ancestry
|
genetics
|
SpyChIP identifies cell type-specific transcription factor occupancy from complex tissues
|
genetics
|
Comparative assessment of computed tomography and magnetic resonance imaging of the spider morph of Python regius and wild type Python regius to evaluate the morphological correlate of the wobble syndrome.
|
genetics
|
Limitations of principal components in quantitative genetic association models for human studies
|
genetics
|
Genome-wide signatures of geographic expansion and breeding process in soybean
|
genomics
|
PeerPub: A device for concurrent operant oral self-administration by multiple rats
|
animal behavior and cognition
|
Structure of the connexin-43 gap junction channel reveals a closed sieve-like molecular gate
|
biochemistry
|
Pre-equilibrium biosensors: A new approach towards rapid and continuous molecular measurements
|
bioengineering
|
Multiplexed Label-Free Biomarker Detection by Targeted Disassembly of Variable-Length DNA Payload Chains
|
bioengineering
|
ChromDMM: A Dirichlet-Multinomial Mixture Model For Clustering Heterogeneous Epigenetic Data
|
bioinformatics
|
ViPal: A Framework for Virulence Prediction of Influenza Viruses with Prior Viral Knowledge Using Genomic Sequences
|
bioinformatics
|
Exploring intra-species diversity through non-redundant pangenome assemblies
|
bioinformatics
|
Solution structure of NPSL2, a regulatory element in the oncomiR-1 RNA
|
biophysics
|
Targeting tumor stemness switch phenotype by activating pathogen induced stem cell niche defense
|
cancer biology
|
Adversary of DNA integrity: a long non-coding RNA stimulates driver oncogenic chromosomal rearrangement in human thyroid cells
|
cancer biology
|
CHA1: A New Combinatorial Therapy That Reciprocally Regulates Wnt and JAK/STAT/Interferon Signaling to Re-program Breast Tumors and the Tumor-Resident Landscape.
|
cancer biology
|
A cancer stem cell population underlies a multi-lineage phenotype and drug resistance in prostate cancer
|
cancer biology
|
Cuticle and cuticular sensilla in Agnostina
|
paleontology
|
Physiological and molecular mechanisms regulated mesophyll conductance under severe drought in water-saving drought-resistant rice
|
physiology
|
SegVeg: Segmenting RGB images into green and senescent vegetation by combining deep and shallow methods
|
plant biology
|
SWEET11 and SWEET12 transporters function in tandem to modulate sugar flux in Arabidopsis: An account of the underlying unique structure-function relationship
|
plant biology
|
Digital twins and hybrid modelling for simulation of physiological variables and stroke risk
|
systems biology
|
An anchored experimental design and meta-analysis approach to address batch effects in large-scale metabolomics
|
systems biology
|
ALS sensitive spinal motor neurons enter a degenerative downward spiral of impaired splicing and proteostasis
|
neuroscience
|
Retinotopic tiling of retinal ganglion cell axons at single-cell precision in the mouse superior colliculus
|
neuroscience
|
Xenon LFP Analysis Platform is a Novel Graphical User Interface for Analysis of Local Field Potential from Large-Scale MEA Recordings
|
neuroscience
|
Effects of variability in manually contoured spinal cord masks on fMRI co-registration and interpretation
|
neuroscience
|
Females outperform males in spatial learning despite increased amyloid plaques and microgliosis in a TgF344-AD rat model of Alzheimer's disease
|
neuroscience
|
siRNA-mediated gene knockdown via electroporation in hydrozoan jellyfish embryos
|
developmental biology
|
Myosin waves and a mechanical asymmetry guide the oscillatory migration of Drosophila cardiac progenitors
|
developmental biology
|
Strategies for sampling pseudo-absences for species distribution models in complex mountainous terrain
|
ecology
|
Footprints of domestication in dry-cured meat Penicillium fungi: convergent specific phenotypes and horizontal gene transfers
|
evolutionary biology
|
Metabolism of glucose activates TORC1 through multiple mechanisms in Saccharomyces cerevisiae
|
genetics
|
Mobile elements in human population-specific genome and phenotype divergence
|
genetics
|
Multiplexed microfluidic chip for cell co-culture
|
bioengineering
|
ScanExitronLR: characterization and quantification of exitron splicing events in long-read RNA-seq data
|
bioinformatics
|
BET inhibition sensitizes immunologically-cold Rb-deficient prostate cancer to immune checkpoint blockade
|
cancer biology
|
Single Nucleus RNA Sequencing of Pre-Malignant Liver Reveals Disease-Associated Hepatocyte State with HCC Prognostic Potential
|
cancer biology
|
Genetic mechanisms and biological processes underlying host response to ophidiomycosis (Snake Fungal Disease) inferred from tissue-specific transcriptome analyses.
|
pathology
|
HPCA1 is required for systemic ROS and calcium cell-to-cell signaling and plant acclimation to stress
|
plant biology
|
Petascale pipeline for precise alignment of images from serial section electron microscopy
|
neuroscience
|
UBQLN2 restrains the domesticated retrotransposon PEG10 to maintain neuronal health in ALS
|
cell biology
|
Environmental predictors of electroactive bacterioplankton in small boreal lakes.
|
microbiology
|
Antiviral roles of interferon regulatory factor (IRF)-1, 3 and 7 against human coronavirus infection
|
microbiology
|
The Envelope Protein of SARS-CoV-2 Inhibits Viral Protein Synthesis and Infectivity of Human Immunodeficiency Virus type 1 (HIV-1)
|
microbiology
|
Optimized production and fluorescent labelling of SARS-CoV-2 Virus-Like-Particles to study virus assembly and entry.
|
microbiology
|
Engineering a Vaccine Platform using Rotavirus A to Express SARS-CoV-2 Spike Epitopes
|
microbiology
|
The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction
|
molecular biology
|
Telomere to telomere sequence of model Aspergillus fumigatus genomes
|
genomics
|
The aggregation potential of Zika virus proteome
|
biophysics
|
MS1/MMD1 homologs in the moss P. patens are required for male and female gametogenesis and likely for sporogenesis
|
plant biology
|
Characteristics of N6-methyladenosine modification during sexual reproduction of Chlamydomonas reinhardtii
|
plant biology
|
Transcriptome analysis reveals robust transcriptional reprogramming during early stages of Cicer-Ascochyta interaction
|
plant biology
|
CryoET Reveals Organelle Phenotypes in Huntington Disease Patient iPSC-Derived and Mouse Primary Neurons
|
neuroscience
|
T cells induce interferon-responsive oligodendrocytes during white matter aging
|
neuroscience
|
Variation in TAF1 expression in female carrier induced pluripotent stem cells and human brain ontogeny has implications for adult neostriatum vulnerability in X-linked Dystonia Parkinsonism
|
neuroscience
|
A Bayesian approach to incorporate structural data into the mapping of genotype to antigenic phenotype of influenza A(H3N2) viruses
|
microbiology
|
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