CShorten/CORD19-Chunk-2 · Datasets at Hugging Face

Unnamed: 0 int64 0 10k	title stringlengths 3 547	abstract stringlengths 10 122k ⌀
5,300	Abstracts of the 9th Congress of the International Pediatric Nephrology Association, August 30–September 4, 1992, Jerusalem, Israel	null
5,301	Neuroimmunomodulation: Stress and immune function: The Lovelace Institutes, Albuquerque, New Mexico 7–9 October 1994	null
5,302	Hinweise auf Artikel in dieser Ausgabe	null
5,303	Joint Esctaic – Sfimar Meeting	null
5,304	Biomedical vignette	null
5,305	Book reviews	null
5,306	Nierenerkrankungen undihre Beziehungen zu Infektherden im Hals-Nasen-Ohrengebiet und an den Zähnen	null
5,307	15(th) Congress of the International Pediatric Nephrology Association: 29 August – 2 September, 2010 New York, NY, USA	null
5,308	ESCP 36th European Symposium on Clinical Pharmacy ‘Implementing Clinical Pharmacy in Community and Hospital Settings: Sharing the Experience’, Istanbul, Turkey 25–27 October 2007; Abstracts	null
5,309	Irish Society of Gastroenterology: Proceedings for summer meeting – 26th/27th May 1995 in Galway	null
5,310	Successive changes in the ultrastructure ofOryza sativa L. cells during growth and aging	The ultrastructure ofOryza sativa L. cells in suspension was determined as cells developed, matured and senesced at 3, 10, and 17 days, respectively, after transfer to fresh medium. Although cultures of 3-day-old cells contained some senescent cells, the symptoms of cell aging were very conspicuous at 10 days and were most pronounced at 17 days. The amount of cytoplasm decreased as the number of lytic areas, myelin figures and vesicle bodies increased. Other noticeable subcellular changes observed were ultrastructural modifications of mitochondria, proplastids, amyloplasts, and nuclei. Such changes were associated with a general deterioration of the lipoprotein complex of the cell during its growth. A fibrous structure without an external membrane was observed and its reported for the first time for cells grown in suspension culture.
5,311	Abstract 7th International Symposium Supportive Care in Cancer, Luxembourg, 20–23 September 1995	null
5,312	The ultrastructure of plasmodesmata	It is suggested that the central strand which traverses plasmodesmata is in open continuity with the endoplasmic reticulum of adjacent cells, and that this strand (desmotubule) represents a modulation of a normal ER membrane so that it comprises solely spherical protein subunits. This concept is used to illustrate how plasmodesmata could form a median nodule or anastomosing central strands. The implications of this model in relation to current theories of symplasmic transport are discussed, and the possibility for further experimental work is outlined.
5,313	Seventeenth Sir Peter Freyer memorial lecture and surgical symposium: September 23rd & 24th, 1993	null
5,314	31st Workshop for Pediatric Research: held at the Kinderklinik of the Georg-August-Universität Göttingen 16–17 February 1995	null
5,315	Irish Society of Gastroenterology: Proceedings of winter meeting held in Dublin on 25th/26th November 1994.	null
5,316	Abstracts of the 64th Annual Conference of IACTS, February 2018	null
5,317	Strongyloidiasis: Epidemiology, clinical manifestations and new methods for diagnosis and treatment	Strongyloidosis is a parasitic disease of the intestines, seen mainly in tropical areas. It is quite likely that, because its manifestations are milder than those of other tropical diseases, it may be overlooked in regions where parasitic diseases such as hookworms and roundworms are endemic. With future improvements in hygiene and the resulting decreases in parasitic diseases, increasing attention will be focused on strongyloidiasis in tropical regions — a phenomenon currently being observed in Okinawa. Studies on the diagnosis and treatment of apparently healthy Strongyloides carriers have only just started. These studies can be expected to play a major role in improving the near-future health and welfare of people in tropical regions of the world. Parasitic diseases in Japan have a strong local character; a long-term eradication program, with due consideration to HTLV-1 infection, must be instituted.
5,318	Abstracts Jahrestagung 2015 der Österreichischen Gesellschaft für Pneumologie: Graz, 15.–17. Oktober 2015	null
5,319	2012 CIS Annual Meeting: Primary Immune Deficiency Diseases North American Conference	null
5,320	Abstracts of the European Association of Nuclear Medicine Congress: 20–24 May, 1990 Amsterdam, The Netherlands	null
5,321	10th Asian Congress of Pediatric Nephrology 2008 (ACPN 2008) Innovation in Prevention and Therapeutic Strategies August 28–30, 2008 Centara Grand & Bangkok Convention Centre at Central World, Bangkok, Thailand	null
5,322	Abstract	null
5,323	20th ECP	null
5,324	Beijing's Hard and Soft Repression in Hong Kong	Hong Kong's new Police Commissioner Chris Tang announced in Beijing on December 7, 2019, that he would use “both hard and soft approaches” to end the anti-government protests. This article argues that such “approaches” amount to physical and non-physical repression—hard power, but employed by Hong Kong, rather than mainland, forces, combined with sharp power exercised by both Beijing and the local authorities. These measures are responses to the limits on what Beijing can do under the “one country, two systems” model. As Beijing cannot send the People's Liberation Army (PLA), it has subverted Hong Kong's once-respected civilian police force to act like the mainland's public security. And as Hong Kong's judiciary is relatively autonomous and many of the arrested would not be convicted or sentenced, the police have resorted to a decapacitation campaign to inflict direct violence on protesters. Moreover, as the city's freedom has allowed the public to support protesters in various ways, Beijing has launched a program of dismissal of pro-democracy individuals in both public and private sectors. To zoom in on Beijing's hard and soft repression, this article examines in closer detail the other “frontliners” at protest sites who provide professional services vital to the sustainability of protests: medics, firefighters, lawyers, journalists, and educators.
5,325	Les exacerbations sévères de l’asthme : quels sont les acteurs saisonniers ? Les infections virales	null
5,326	ESPR 2017	null
5,327	In Kürze	null
5,328	Abstracts_Poster presentations	null
5,329	SPR 2013	null
5,330	Abstract	null
5,331	Abstracts Scientific Papers Honorary Lectures Categorical Courses Workshops State-of-the-Art Symposia	null
5,332	Satellite Symposia and Meet-the-Professor Sessions: Satellite Symposium I	null
5,333	B scientific sessions (SS)	null
5,334	2001 Scientific Session of the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) St. Louis, Missouri, USA, 18–21 April 2001 Poster presentations	null
5,335	C scientific exhibits (SE)	null
5,336	Posters	null
5,337	Scientific Programme — Abstracts	null
5,338	3rd Central European Congress of Surgery, Norman Barrett Symposium & 5th Croatian Congress of Surgery with International Participation. Dubrovnik, April 28–May 1, 2010. Guest Editor: Božidar Župančić (Zagreb, Croatia)	null
5,339	25th Annual Meeting of the Austrian Society of Transplantation, Transfusion and Genetics Graz, October 19–21, 2011	null
5,340	8th Annual Meeting of Chinese College of Surgeons and 19th Annual Meeting of the European Society of Surgery: Beijing, May 15—17, 2015	null
5,341	34th Seminar of the Austrian Society for Surgical Research. Wagrain, November 11–13, 2010. Guest Editor: H. Cerwenka, Graz, Austria	null
5,342	48th Annual Meeting of the Austrian Society of Surgery, Graz, June 7–9, 2007	null
5,343	50th Annual Meeting of the Austrian Society of Surgery. Vienna, June 18–20, 2009. Guest Editors: Albert Tuchmann, Erhard Schwanzer, Benedikt Walzel	null
5,344	55th Annual Meeting of the Austrian Society of Surgery: Graz, June 25—27, 2014	null
5,345	Abstracts of the world congresses	null
5,346	National scientific medical meeting 1996 abstracts	null
5,347	Review of the proceedings	null
5,348	Waterford Surgical October Club Royal Academy of Medicine, Surgical Section proceedings of meeting held 19th October 1996 at Waterford Regional Hospital	null
5,349	Postgraduate Course: Integrating Basic Science into Clinical Practice	null
5,350	Potential therapies for coronaviruses	Coronavirus replication offers several attractive targets for chemotherapy. These include: viral entry (inhibited by chloroquine and peptides); viral RNA (targeted by antisense approaches/RNAi); the main protease 3CLpro (inhibited by peptidic molecules such as HIV-1 protease inhibitors and miscellaneous compounds); the accessory protease(s) PLpro(s) (inhibited by zinc ions); RNA-dependent RNA polymerase (inhibited by aurintricarboxylic acid and antisense approaches); and helicase (inhibited by bananins). Chloroquine and HIV-1 protease inhibitors (with well-known toxicity profiles) should be considered for clinical tests if severe acute respiratory syndrome (SARS) re-emerges; however, there are other attractive compounds. Lessons should be learnt from AIDS research for choosing the best strategies.
5,351	Symposium	null
5,352	Posters	null
5,353	10th Congress of International Society of Systemic Auto-Inflammatory Diseases (ISSAID): Genoa, Italy. 31 March - 3 April 2019	null
5,354	Symposia	null
5,355	April 2020 People & Events	null
5,356	Calendar	null
5,357	Komkommertijd	null
5,358	Posttraumatic stress disorder in survivors of acute respiratory distress syndrome (ARDS) and septic shock	Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) define medical conditions of acute respiratory insufficiency deriving from direct and indirect damage of the alveolar parenchyma and often associated with multiorgan dysfunction (MODS). As a rule, intensive care is based on mechanical ventilation often requiring high doses of sedatives and narcotics. Despite major progress in intensive care medicine the rate of mortality is still very high. Whereas in the past the level of medical progress has been rated based on the mortality rate alone, the many negative somatic and psychological sequelae in long-term-survivors of ARDS are only now being appreciated. From a perspective of C/L psychiatry persisting cognitive dysfunctions, anxiety and mood disorders, posttraumatic stress disorders (PTSD) in their negative impact on health-related quality of life are intensively investigated. In the etiopathogenesis of PTSD associated with ALI/ARDS, many influences have to be discussed, e.g., increases in CO(2) triggering panic affects, a mismatch of norepinephric overstimulation and cortisol insufficiency, negative effects of high doses of benzodiazepines resulting in oversedation, prolonged phases of weaning and more frequent states of delirium. Consolidation and retrieval of traumatic memories of the ICU stay are influenced by complex factors. From a clinical point of view prophylactic stress doses of hydrocortisone may reduce the major risk of PTSD associated with ALI / ARDS.
5,359	Physicians Poster Sessions	null
5,360	1345 The Use of Hood Cpap to Improve Compliance with Non-Invasive Ventilation (NIV): A Single Centre Experience	Background: The Ca-Star CPAP (Continuous Positive Airway pressure) Hood is a relatively novel method of delivering CPAP to infants and children. Aims: To report the experience of a single centre in the application of Hood CPAP for provision of NIV. Methods: We retrospectively analysed all children admitted to a six bedded PCCU for NIV over a 2 year period. Children included in the study were those who had failed conventional mask CPAP yet gone on to tolerate Hood CPAP for >24 hours or until NIV was no longer required. Results: Six patients (4 males) were identified with mean age of 14 months (range 6 months - 3 years). The reasons for failing conventional CPAP were pressure areas on face (1), child intolerance of mask pressing on face (4) and inability to get seal due to facial abnormalities (1). The indications for CPAP included primary Respiratory condition (5) and neuromuscular (1). The underlying co-morbidities were ex pre-maturity (2), Trisomy 21 (2), congenital abnormalities (1) and none (1). Hypothermia was observed as a complication in 2 patients. Conclusions: Intolerance of the mask is a problem in the ‘toddler’ age range, and in our experience the HOOD is an under-utilised but useful interface to provide CPAP in these patient groups. It can be used successfully as an alternative to intubation, for relief of facial pressure areas and to provide an effective seal in case of facial abnormalities.
5,361	Scientific Abstracts	null
5,362	THE EFFECT OF GESTATIONAL AGE AND LABOR UPON INTRACELLULAR SURVIVAL OF HERPES SIMPLEX VIRUS (HSV)	Neonatal HSV infection is often characterized by rapid, life-threatening dissemination. Perinatal immunologic factors examined to date incompletely account for this tendency to disseminate, for the rapid disappearance of this vulnerability early in postnatal life, and for the disproportionate occurrence in prematures. To determine a possible influence of gestational age or perinatal events upon this phenomenon, we studied 29 placental specimens of varying gestational age and mode of delivery. The intracellular survival of type 2 HSV within placental lymphocytes was assessed at 48 hour intervals for 6 days to determine the frequency and magnitude of virus titer changes. Early (0-48hrs) titer increases were significantly (p=0.015) more frequent in specimens with gestational age ≤ 35 wks (3/8) than those with ≥ 36 wks (0/21) gestations. Titer increases from 48 to 96 hours were common (14/29) but bore no relationship to gestational age, labor, or mode of delivery. Most importantly, late (>96 hrs) titer increases were most influenced by the occurrence of labor and unrelated to gestational age. Late titer increases did not occur in specimens from caesarian section without labor(0/12) and were significantly (p=0.023) more frequent in specimens where labor occurred (7/17). These findings are consistent with the hypothesis that early gestational age and the occurrence of labor transiently provide a more permissive intracellular environment for HSV replication and dissemination.
5,363	Publication only	null
5,364	POSTER SESSION I	null
5,365	President’s Plenary Session	null
5,366	Scientific Abstracts	null
5,367	Pathobiology	null
5,368	Scientific Abstracts	null
5,369	DETECTION OF DONOR'S LYMPHOCYTES IN THE PERIPHERAL BLOOD OF NEONATES FOLLOWING EXCHANGE-TRANSFUSION	Twenty preterm and term female neonates were exchange-transfused with males donor fresh blood during their first days of life because of hyperbilirubinaemia or severe septicaemia. In order to study the presence of donor lymphocytes in the neonates peripheral blood, chromosome studies were performed immediately after,12 and 72 hours following the exchange transfusion. We used the fluorescent-binding technique in order to distinguish the donor's cells by the presence of the γ-chromosone or other fluorescent markers in at least 300 mitotic figures in each speciment. We found that in jaundiced babies immediately following exchange transfusion less than 10% of the lymphocytes came from the donor and 12 hours later only 1-2% were still present.However in neonates exchange-transfusion for septicaemia the percentage of donor's lymphocytes immediately following the proceedure sometimes reached 50% and dropped to less than 10% by 12 hours.This shows the inability of the depressed by the infection host defence mechanisms of the newborn to deal with the donor's lymphocytes.
5,370	Techniques	null
5,371	POLYMORPHONUCLEAR LEUKOCYTE SUPEROXIDE ANION GENERATION IN CRITICALLY ILL CHILDREN	Generation of active oxygen species by activated PMNs plays a paramont role in human immunologic defenses. However, numerous in vitro experiments have demonstrated that inadvertant release of highly reactive oxygen metabolites by the PMN into the surrounding milieu results in autoinjury and is associated with diffuse capillary leak syndromes (septic shock, ARDS). NADPH oxidoreductase, the superoxide anion generating enzyme, is a PMN membrane bound flavoprotein normally dormant but inducible by a variety of agents. We studied the specific activity of this enzyme in critically ill children to determine if detection of its activation might provide an early clue of impending in inflammatory amplification injury. Venous blood specimens from 12 healthy young adult controls reflected an induced enzyme activity of 8.23 ± 2.1 nmoles superoxide/min./10(6) PMNs ± S.D. Similarly the induced activity in a group of 6 pediatric intensive care patients without evidence of capillary leak syndrome was 7.3 ± 2.2 . In constrast the mean induced activity from a group of 6 critically ill children with evidence of capillary leak syndrome was 3.0 ± 1.1 (p<.001). No activity was demonstrated in non-induced PMNs from any group. No differences in induced enzyme activity were appreciated between venous and arterial blood samples. Such findings may demonstrate the phenomena of desensitization of previously in vivo activated neutrophils to additional stimulation, and may represent a host defense which minimizes autoinjury.
5,372	Scientific Abstracts	null
5,373	Bone and Soft Tissue Pathology	null
5,374	Genitourinary	null
5,375	Scientific Abstracts	null
5,376	Pathobiology	null
5,377	1347 Non Invasive Ventilation in Pediatric Intensive Care Unit	Objective: The aim of this study was to investigate the benefit of the Non Invasive Ventilation (NIV) in children admitted to the Pediatric Intensive Care Unit (PICU). Methods: We studied 22 children supported by NIV, aged 1 month to 15 years. The duration of the study was 4 years (January 2006- December 2009). The total number of admissions to ICU during this period was 759 (2,9% supported by NIV). The causes of the respiratory failure in these children supported by NIV were: chronic diseases-infection (n=11; 50%), neuromuscular diseases (n=4; 18,18%), renal transplantations-immunosuppression (n=3; 13,63%), leukemias (n=2; 9,09%), respiratory infections (n=2; 9,09%). We selected the Biphasic Ventilation mode (Bi-Vent) by facial mask, because our patients were in severe respiratory distress. The parameters in this mode were as follow: PIP: 10-16 cmH2O and PEEP 6-12 cmH2O. The mean duration of NIV was 4 days (3 hours to 14 days). Results: Facial mask was well tolerated and with no injuries from her use. Results showed that 19 patients (86,36%) recovered and 3 patients (13,63%) died because of their underlying disease and not from the respiratory failure. Two of our patients continued the NIV ventilation as home care treatment. Conclusions: NIV support of respiratory failure is a very useful tool in the pediatric intensivists' hands because it is good alternative to mechanical ventilation. It is well tolerated, reduces the need of sedation and the PICU stay in these patients.
5,378	CEFOTAXIME IN THE TREATMENT OF BACTERIAL MENINGITIS	We evaluated the efficacy of cefotaxime in the treatment of bacterial meningitis and the diffusion of the drug into CSF. Eleven children(9 days to 5 yrs) with meningitis due to H. influenzae (7 cases), S. pneumoniae(2) , group B streptococcus (1) , and Salmonella sp.(1), were treated with 40 mg/kg of IV cefotaxime q6hrs. Cefotaxime levels were determined by HPLC. The mean cefotaxime plasma level 3 hrs after a dose early in the treatment was 14.1 mg/L(range 5.1-42.2 mg/L), and the mean CSF level was 3.9 mg/L(0.7-16.6 mg/L). The mean CSF diffusion rate was 26.4%. At the end of treatment, the mean plasma level was 7.9 mg/L(1.5-13.6 mg/L) and the mean CSF level was 1.23 mg/L(0.5-3.1 mg/L) representing a mean diffusion rate of 21.9%. Cefotaxime MBC for the infecting organisms ranged between 0.015 mg/L and 0.25 mg/L. CSF was bactericidal to the infecting organisms at dilutions between 8 and 256. The CSF diffusion correlated positively with the cefotaxime plasma level (r=0.86), CSF protein (r=0.63), CSF leukocyte count (r=0.61) and negatively with CSF sugar (r=-0.37).All patients responded well to treatment with no apparent sequelae. Serial levels were also determined in 5 infants with ventriculostomies. Following a single dose of 40 mg/kg, the mean cefotaxime CSF levels (and mean plasma levels) were 6.6 mg/L(28.4 mg/L) at 2 hrs, 5.7 mg/L(8.9 mg/L) at 4 hrs, and 4.5 mg/L (1.8 mg/L) at 6 hrs. Cefotaxime diffuses sufficiently and consistently into CSF. Further assessment of its efficacy in the treatment of childhood meningitis is warranted.
5,379	Infectious Disease Pathology	null
5,380	Physicians Poster Abstracts: EBMT 2012	null
5,381	President’s Plenary Session	null
5,382	Bone and Soft Tissue Pathology	null
5,383	1348 Influenza a H1N1 Virus Infection in a Pediactric Intensive Care Unit	Background: the main form of clinical presentation in critically ill patients with H1N1 infection is rapidly progressive respiratory failure, shock, neurological involvement and renal failure. Children with comorbidity and aged < 2 years are at particular risk. Methods: a descriptive, retrospective study on the clinical presentation and management of patients with H1N1 infection was performed in a Pediatric Intensive Care Unit (PICU). All children admitted in PICU of Coimbra's Pediatrics Hospital (CPH) were described, from July 15(th) to November 30(th) of 2009. Results: during this period, 241 children with laboratory confirmation of H1N1 infection were observed in CPH, of whom 38 (16%) required hospitalization, 4 (1.7%) in PICU-CPH. The age ranged from 4 months to 21 years. Three patients had previous co-morbidities. All met clinical criteria for H1N1 infection and were admitted with respiratory distress (4), rapidly progressive and evolution to ARDS (2), associated with shock (2) and lethargy (2). Three patients required mechanical ventilation (conventional and high-frequency oscillatory ventilation); the duration ranged between 4-12 days. Two patients received intravenous catecholamines support, two developed acute renal failure and two had pancytopenia. There were two bacterial coinfections. All received treatment with oseltamivir. Length of PICU stay ranged from 5-22 days, with a favorable outcome in all cases. Conclusion: in the 1st peak of H1N1 outbreak, 10% of the hospitalized children required PICU admission. Despite severe respiratory disease and multiple organ dysfunction, a good outcome was achieved, with no mortality.
5,384	1346 Flutisane Propionate in Prevention of Rhynitis Alergica with Children	Introduction: In childhood rhynitis alergica is medical and social problem. The nasal mucous membrane first gets in touch with a lot of causes, including causes of allergy. Objective: Improvement of quality of the life with children who are treated with Fluticasone propionate. Material and Methods: We processed the data from medical records of 58 children on the age of 6 and 12 years in the period of 2 years (2008 - 2009), and 43 children from them were put on prevention with Fluticasone propionate. For processing the data we used analytic and descriptive method. Results: We processed 58 cases with rhynitis alergica proved with: skin tests or RIDA screen tests, total IgE, eosinophyles in nose and drainage secretion. 15 children were put only on symptom's therapy, and 43 children were put on therapy with Fluticasone propionate in a period of a few months. With 9 children rhinitis alergica was followed by conjuctivitis alergica and they get antihistaminic medicaments. All children that were put on prevention had minimal symptoms of Rhynitis and they had normal physical activities and attend a school regularly. Conclusion: Suitable and therapy on time allows normal and healthy life and free activity with children who have proved rhynitis alergica.
5,385	Scientific Abstracts	null
5,386	Infectious Disease Pathology	null
5,387	Scientific Program & Abstracts: 57™ Annual Meeting March 24–27, 2010	null
5,388	Scientific Abstracts	null
5,389	Design and application of the method for isolating magnetotactic bacteria	A simple apparatus was designed to effectively isolate magnetotactic bacteria from soils or sediments based on their magnetotaxis. Through a series of processes including sample incubation, MTB harvesting, isolation, purification and identification, several strains of bacteria were isolated from the samples successfully. By Transmission Electron Microscopy (TEM) and Energy-Dispersive X-ray Analysis (EDXA), these bacteria were certificated to be magnetotactic bacteria. The phylogenetic relationship between the isolated magnetic strains and some known magnetotactic bacteria was inferred by the construction of phylogenetic tree based on 16SrDNA sequences. This apparatus has been proven to have the advantages of being inexpensive, simple to assemble, easy to perform and highly efficient to isolate novel magnetotactic bacteria. The research indicated that the combined approach of harvesting MTB by home-made apparatus and the method of plate colony isolation could purify and isolate magnetotactic bacteria effectively.
5,390	A GMC Oxidoreductase GmcA Is Required for Symbiotic Nitrogen Fixation in Rhizobium leguminosarum bv. viciae	GmcA is a FAD-containing enzyme belonging to the GMC (glucose-methanol-choline oxidase) family of oxidoreductases. A mutation in the Rhizobium leguminosarum gmcA gene was generated by homologous recombination. The mutation in gmcA did not affect the growth of R. leguminosarum, but it displayed decreased antioxidative capacity at H(2)O(2) conditions higher than 5 mM. The gmcA mutant strain displayed no difference of glutathione reductase activity, but significantly lower level of the glutathione peroxidase activity than the wild type. Although the gmcA mutant was able to induce the formation of nodules, the symbiotic ability was severely impaired, which led to an abnormal nodulation phenotype coupled to a 30% reduction in the nitrogen fixation capacity. The observation on ultrastructure of 4-week pea nodules showed that the mutant bacteroids tended to start senescence earlier and accumulate poly-β-hydroxybutyrate (PHB) granules. In addition, the gmcA mutant was severely impaired in rhizosphere colonization. Real-time quantitative PCR showed that the gmcA gene expression was significantly up-regulated in all the detected stages of nodule development, and statistically significant decreases in the expression of the redoxin genes katG, katE, and ohrB were found in gmcA mutant bacteroids. LC-MS/MS analysis quantitative proteomics techniques were employed to compare differential gmcA mutant root bacteroids in response to the wild type infection. Sixty differentially expressed proteins were identified including 33 up-regulated and 27 down-regulated proteins. By sorting the identified proteins according to metabolic function, 15 proteins were transporter protein, 12 proteins were related to stress response and virulence, and 9 proteins were related to transcription factor activity. Moreover, nine proteins related to amino acid metabolism were over-expressed.
5,391	The polymerase chain reaction and pathology practice	Pathology practice is increasingly augmented with molecular tests for improved diagnostics and patient management. The polymerase chain reaction (PCR) is foremost amongst these techniques. This review explains the principles of PCR and the methodological factors that contribute to a successful assay. Key PCR technique variations, such as reverse transcription (RT)-PCR and quantitative real-time (q) PCR, are described and an overview is provided of how PCR products are analysed. The review includes examples of PCR usage in clinical practice for the detection of infectious and genetic diseases, for tumour diagnostics and in molecular forensic applications such as specimen identity confirmation.
5,392	News in Brief	null
5,393	Rodent Diagnostic Testing	Clinical medicine is an important part of scientific medicine that is all too often neglected when treating rodents and small mammal pets. As with more traditional pets, a progressive diagnostic regimen should include a thorough history, clinical signs, physical examination, and laboratory findings.
5,394	The American Organization of Nurse Executives and Global Citizenship	Globalization is impacting many aspects of American society, and nursing has especially been impacted over the past few decades. Global issues such as nurse migration, pandemic infections, natural disasters, man-made disasters, and geopolitical unrest have made it clear that no nation can remain isolated and unaffected by world events and trends. With these facts, the American Organization of Nurse Executives' (AONE) leaders and members increasingly understand that leaders along with their communities and health care organizations work in all arenas, from local to national and international.
5,395	Paraplegia in a Domestic Ferret (Mustela Putorius Furo) Secondary to Metastatic Adrenocortical Carcinoma with Myxoid Differentiation	Neurologic disease is a common presentation of domestic ferrets (Mustela putorius furo) with infectious, neoplastic, and traumatic etiologies documented. Adrenocortical neoplasia is also well documented in domestic ferrets, with metastatic lesions rarely described. This case report describes an abnormal presentation of adrenocortical adenocarcinoma with myxoid differentiation and subsequent metastasis to the spinal cord and vertebral bodies, resulting in hind limb paraplegia in an adult spayed female ferret.
5,396	Systemic Infection Due to Candida parapsilosis in a Domestic Ferret (Mustela putorius furo)	An 18-month-old castrated male ferret (Mustela putorius furo) was presented to the veterinary hospital for acute collapse but died despite initiation of emergency treatment. The body was submitted for a complete postmortem examination. The pathologist determined the ferret was suffering from severe necrotizing encephalitis, necrogranulomatous mediastinal lymphadenitis, and ulcerative dermatitis attributable to systemic Candida parapsilosis. This is the first report of systemic Candida parapsilosis in a ferret.
5,397	Current Approach to Rodents as Patients	Rodent species are routinely presented to veterinary hospitals for wellness checks and different illnesses. When rodents are presented to the veterinarian for diagnosis and treatment, they deserve the same thorough approach that any other domestic species receives. The purpose of this article is to provide readers a review of the current information regarding examination, diagnosis, and treatment of some of the most common conditions for which rodent patients are presented. This article will cover 5 of the most common rodent species presented to veterinarians: guinea pigs, chinchillas, rats, mice, and hamsters.
5,398	Technology confronts SARS	null
5,399	Respiratory pharmacology: In defense of the lung: innovations to bolster or prevent acute and chronic lung diseases	null

5,300

Abstracts of the 9th Congress of the International Pediatric Nephrology Association, August 30–September 4, 1992, Jerusalem, Israel

null

5,301

Neuroimmunomodulation: Stress and immune function: The Lovelace Institutes, Albuquerque, New Mexico 7–9 October 1994

null

5,302

Hinweise auf Artikel in dieser Ausgabe

null

5,303

Joint Esctaic – Sfimar Meeting

null

5,304

Biomedical vignette

null

5,305

Book reviews

null

5,306

Nierenerkrankungen undihre Beziehungen zu Infektherden im Hals-Nasen-Ohrengebiet und an den Zähnen

null

5,307

15(th) Congress of the International Pediatric Nephrology Association: 29 August – 2 September, 2010 New York, NY, USA

null

5,308

ESCP 36th European Symposium on Clinical Pharmacy ‘Implementing Clinical Pharmacy in Community and Hospital Settings: Sharing the Experience’, Istanbul, Turkey 25–27 October 2007; Abstracts

null

5,309

Irish Society of Gastroenterology: Proceedings for summer meeting – 26th/27th May 1995 in Galway

null

5,310

Successive changes in the ultrastructure ofOryza sativa L. cells during growth and aging

The ultrastructure ofOryza sativa L. cells in suspension was determined as cells developed, matured and senesced at 3, 10, and 17 days, respectively, after transfer to fresh medium. Although cultures of 3-day-old cells contained some senescent cells, the symptoms of cell aging were very conspicuous at 10 days and were most pronounced at 17 days. The amount of cytoplasm decreased as the number of lytic areas, myelin figures and vesicle bodies increased. Other noticeable subcellular changes observed were ultrastructural modifications of mitochondria, proplastids, amyloplasts, and nuclei. Such changes were associated with a general deterioration of the lipoprotein complex of the cell during its growth. A fibrous structure without an external membrane was observed and its reported for the first time for cells grown in suspension culture.

5,311

Abstract 7th International Symposium Supportive Care in Cancer, Luxembourg, 20–23 September 1995

null

5,312

The ultrastructure of plasmodesmata

It is suggested that the central strand which traverses plasmodesmata is in open continuity with the endoplasmic reticulum of adjacent cells, and that this strand (desmotubule) represents a modulation of a normal ER membrane so that it comprises solely spherical protein subunits. This concept is used to illustrate how plasmodesmata could form a median nodule or anastomosing central strands. The implications of this model in relation to current theories of symplasmic transport are discussed, and the possibility for further experimental work is outlined.

5,313

Seventeenth Sir Peter Freyer memorial lecture and surgical symposium: September 23rd & 24th, 1993

null

5,314

31st Workshop for Pediatric Research: held at the Kinderklinik of the Georg-August-Universität Göttingen 16–17 February 1995

null

5,315

Irish Society of Gastroenterology: Proceedings of winter meeting held in Dublin on 25th/26th November 1994.

null

5,316

Abstracts of the 64th Annual Conference of IACTS, February 2018

null

5,317

Strongyloidiasis: Epidemiology, clinical manifestations and new methods for diagnosis and treatment

Strongyloidosis is a parasitic disease of the intestines, seen mainly in tropical areas. It is quite likely that, because its manifestations are milder than those of other tropical diseases, it may be overlooked in regions where parasitic diseases such as hookworms and roundworms are endemic. With future improvements in hygiene and the resulting decreases in parasitic diseases, increasing attention will be focused on strongyloidiasis in tropical regions — a phenomenon currently being observed in Okinawa. Studies on the diagnosis and treatment of apparently healthy Strongyloides carriers have only just started. These studies can be expected to play a major role in improving the near-future health and welfare of people in tropical regions of the world. Parasitic diseases in Japan have a strong local character; a long-term eradication program, with due consideration to HTLV-1 infection, must be instituted.

5,318

Abstracts Jahrestagung 2015 der Österreichischen Gesellschaft für Pneumologie: Graz, 15.–17. Oktober 2015

null

5,319

2012 CIS Annual Meeting: Primary Immune Deficiency Diseases North American Conference

null

5,320

Abstracts of the European Association of Nuclear Medicine Congress: 20–24 May, 1990 Amsterdam, The Netherlands

null

5,321

10th Asian Congress of Pediatric Nephrology 2008 (ACPN 2008) Innovation in Prevention and Therapeutic Strategies August 28–30, 2008 Centara Grand & Bangkok Convention Centre at Central World, Bangkok, Thailand

null

5,322

Abstract

null

5,323

20th ECP

null

5,324

Beijing's Hard and Soft Repression in Hong Kong

Hong Kong's new Police Commissioner Chris Tang announced in Beijing on December 7, 2019, that he would use “both hard and soft approaches” to end the anti-government protests. This article argues that such “approaches” amount to physical and non-physical repression—hard power, but employed by Hong Kong, rather than mainland, forces, combined with sharp power exercised by both Beijing and the local authorities. These measures are responses to the limits on what Beijing can do under the “one country, two systems” model. As Beijing cannot send the People's Liberation Army (PLA), it has subverted Hong Kong's once-respected civilian police force to act like the mainland's public security. And as Hong Kong's judiciary is relatively autonomous and many of the arrested would not be convicted or sentenced, the police have resorted to a decapacitation campaign to inflict direct violence on protesters. Moreover, as the city's freedom has allowed the public to support protesters in various ways, Beijing has launched a program of dismissal of pro-democracy individuals in both public and private sectors. To zoom in on Beijing's hard and soft repression, this article examines in closer detail the other “frontliners” at protest sites who provide professional services vital to the sustainability of protests: medics, firefighters, lawyers, journalists, and educators.

5,325

Les exacerbations sévères de l’asthme : quels sont les acteurs saisonniers ? Les infections virales

null

5,326

ESPR 2017

null

5,327

In Kürze

null

5,328

Abstracts_Poster presentations

null

5,329

SPR 2013

null

5,330

Abstract

null

5,331

Abstracts Scientific Papers Honorary Lectures Categorical Courses Workshops State-of-the-Art Symposia

null

5,332

Satellite Symposia and Meet-the-Professor Sessions: Satellite Symposium I

null

5,333

B scientific sessions (SS)

null

5,334

2001 Scientific Session of the Society of American Gastrointestinal and Endoscopic Surgeons (SAGES) St. Louis, Missouri, USA, 18–21 April 2001 Poster presentations

null

5,335

C scientific exhibits (SE)

null

5,336

Posters

null

5,337

Scientific Programme — Abstracts

null

5,338

3rd Central European Congress of Surgery, Norman Barrett Symposium & 5th Croatian Congress of Surgery with International Participation. Dubrovnik, April 28–May 1, 2010. Guest Editor: Božidar Župančić (Zagreb, Croatia)

null

5,339

25th Annual Meeting of the Austrian Society of Transplantation, Transfusion and Genetics Graz, October 19–21, 2011

null

5,340

8th Annual Meeting of Chinese College of Surgeons and 19th Annual Meeting of the European Society of Surgery: Beijing, May 15—17, 2015

null

5,341

34th Seminar of the Austrian Society for Surgical Research. Wagrain, November 11–13, 2010. Guest Editor: H. Cerwenka, Graz, Austria

null

5,342

48th Annual Meeting of the Austrian Society of Surgery, Graz, June 7–9, 2007

null

5,343

50th Annual Meeting of the Austrian Society of Surgery. Vienna, June 18–20, 2009. Guest Editors: Albert Tuchmann, Erhard Schwanzer, Benedikt Walzel

null

5,344

55th Annual Meeting of the Austrian Society of Surgery: Graz, June 25—27, 2014

null

5,345

Abstracts of the world congresses

null

5,346

National scientific medical meeting 1996 abstracts

null

5,347

Review of the proceedings

null

5,348

Waterford Surgical October Club Royal Academy of Medicine, Surgical Section proceedings of meeting held 19th October 1996 at Waterford Regional Hospital

null

5,349

Postgraduate Course: Integrating Basic Science into Clinical Practice

null

5,350

Potential therapies for coronaviruses

Coronavirus replication offers several attractive targets for chemotherapy. These include: viral entry (inhibited by chloroquine and peptides); viral RNA (targeted by antisense approaches/RNAi); the main protease 3CLpro (inhibited by peptidic molecules such as HIV-1 protease inhibitors and miscellaneous compounds); the accessory protease(s) PLpro(s) (inhibited by zinc ions); RNA-dependent RNA polymerase (inhibited by aurintricarboxylic acid and antisense approaches); and helicase (inhibited by bananins). Chloroquine and HIV-1 protease inhibitors (with well-known toxicity profiles) should be considered for clinical tests if severe acute respiratory syndrome (SARS) re-emerges; however, there are other attractive compounds. Lessons should be learnt from AIDS research for choosing the best strategies.

5,351

Symposium

null

5,352

Posters

null

5,353

10th Congress of International Society of Systemic Auto-Inflammatory Diseases (ISSAID): Genoa, Italy. 31 March - 3 April 2019

null

5,354

Symposia

null

5,355

April 2020 People & Events

null

5,356

Calendar

null

5,357

Komkommertijd

null

5,358

Posttraumatic stress disorder in survivors of acute respiratory distress syndrome (ARDS) and septic shock

Acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) define medical conditions of acute respiratory insufficiency deriving from direct and indirect damage of the alveolar parenchyma and often associated with multiorgan dysfunction (MODS). As a rule, intensive care is based on mechanical ventilation often requiring high doses of sedatives and narcotics. Despite major progress in intensive care medicine the rate of mortality is still very high. Whereas in the past the level of medical progress has been rated based on the mortality rate alone, the many negative somatic and psychological sequelae in long-term-survivors of ARDS are only now being appreciated. From a perspective of C/L psychiatry persisting cognitive dysfunctions, anxiety and mood disorders, posttraumatic stress disorders (PTSD) in their negative impact on health-related quality of life are intensively investigated. In the etiopathogenesis of PTSD associated with ALI/ARDS, many influences have to be discussed, e.g., increases in CO(2) triggering panic affects, a mismatch of norepinephric overstimulation and cortisol insufficiency, negative effects of high doses of benzodiazepines resulting in oversedation, prolonged phases of weaning and more frequent states of delirium. Consolidation and retrieval of traumatic memories of the ICU stay are influenced by complex factors. From a clinical point of view prophylactic stress doses of hydrocortisone may reduce the major risk of PTSD associated with ALI / ARDS.

5,359

Physicians Poster Sessions

null

5,360

1345 The Use of Hood Cpap to Improve Compliance with Non-Invasive Ventilation (NIV): A Single Centre Experience

Background: The Ca-Star CPAP (Continuous Positive Airway pressure) Hood is a relatively novel method of delivering CPAP to infants and children. Aims: To report the experience of a single centre in the application of Hood CPAP for provision of NIV. Methods: We retrospectively analysed all children admitted to a six bedded PCCU for NIV over a 2 year period. Children included in the study were those who had failed conventional mask CPAP yet gone on to tolerate Hood CPAP for >24 hours or until NIV was no longer required. Results: Six patients (4 males) were identified with mean age of 14 months (range 6 months - 3 years). The reasons for failing conventional CPAP were pressure areas on face (1), child intolerance of mask pressing on face (4) and inability to get seal due to facial abnormalities (1). The indications for CPAP included primary Respiratory condition (5) and neuromuscular (1). The underlying co-morbidities were ex pre-maturity (2), Trisomy 21 (2), congenital abnormalities (1) and none (1). Hypothermia was observed as a complication in 2 patients. Conclusions: Intolerance of the mask is a problem in the ‘toddler’ age range, and in our experience the HOOD is an under-utilised but useful interface to provide CPAP in these patient groups. It can be used successfully as an alternative to intubation, for relief of facial pressure areas and to provide an effective seal in case of facial abnormalities.

5,361

Scientific Abstracts

null

5,362

THE EFFECT OF GESTATIONAL AGE AND LABOR UPON INTRACELLULAR SURVIVAL OF HERPES SIMPLEX VIRUS (HSV)

Neonatal HSV infection is often characterized by rapid, life-threatening dissemination. Perinatal immunologic factors examined to date incompletely account for this tendency to disseminate, for the rapid disappearance of this vulnerability early in postnatal life, and for the disproportionate occurrence in prematures. To determine a possible influence of gestational age or perinatal events upon this phenomenon, we studied 29 placental specimens of varying gestational age and mode of delivery. The intracellular survival of type 2 HSV within placental lymphocytes was assessed at 48 hour intervals for 6 days to determine the frequency and magnitude of virus titer changes. Early (0-48hrs) titer increases were significantly (p=0.015) more frequent in specimens with gestational age ≤ 35 wks (3/8) than those with ≥ 36 wks (0/21) gestations. Titer increases from 48 to 96 hours were common (14/29) but bore no relationship to gestational age, labor, or mode of delivery. Most importantly, late (>96 hrs) titer increases were most influenced by the occurrence of labor and unrelated to gestational age. Late titer increases did not occur in specimens from caesarian section without labor(0/12) and were significantly (p=0.023) more frequent in specimens where labor occurred (7/17). These findings are consistent with the hypothesis that early gestational age and the occurrence of labor transiently provide a more permissive intracellular environment for HSV replication and dissemination.

5,363

Publication only

null

5,364

POSTER SESSION I

null

5,365

President’s Plenary Session

null

5,366

Scientific Abstracts

null

5,367

Pathobiology

null

5,368

Scientific Abstracts

null

5,369

DETECTION OF DONOR'S LYMPHOCYTES IN THE PERIPHERAL BLOOD OF NEONATES FOLLOWING EXCHANGE-TRANSFUSION

Twenty preterm and term female neonates were exchange-transfused with males donor fresh blood during their first days of life because of hyperbilirubinaemia or severe septicaemia. In order to study the presence of donor lymphocytes in the neonates peripheral blood, chromosome studies were performed immediately after,12 and 72 hours following the exchange transfusion. We used the fluorescent-binding technique in order to distinguish the donor's cells by the presence of the γ-chromosone or other fluorescent markers in at least 300 mitotic figures in each speciment. We found that in jaundiced babies immediately following exchange transfusion less than 10% of the lymphocytes came from the donor and 12 hours later only 1-2% were still present.However in neonates exchange-transfusion for septicaemia the percentage of donor's lymphocytes immediately following the proceedure sometimes reached 50% and dropped to less than 10% by 12 hours.This shows the inability of the depressed by the infection host defence mechanisms of the newborn to deal with the donor's lymphocytes.

5,370

Techniques

null

5,371

POLYMORPHONUCLEAR LEUKOCYTE SUPEROXIDE ANION GENERATION IN CRITICALLY ILL CHILDREN

Generation of active oxygen species by activated PMNs plays a paramont role in human immunologic defenses. However, numerous in vitro experiments have demonstrated that inadvertant release of highly reactive oxygen metabolites by the PMN into the surrounding milieu results in autoinjury and is associated with diffuse capillary leak syndromes (septic shock, ARDS). NADPH oxidoreductase, the superoxide anion generating enzyme, is a PMN membrane bound flavoprotein normally dormant but inducible by a variety of agents. We studied the specific activity of this enzyme in critically ill children to determine if detection of its activation might provide an early clue of impending in inflammatory amplification injury. Venous blood specimens from 12 healthy young adult controls reflected an induced enzyme activity of 8.23 ± 2.1 nmoles superoxide/min./10(6) PMNs ± S.D. Similarly the induced activity in a group of 6 pediatric intensive care patients without evidence of capillary leak syndrome was 7.3 ± 2.2 . In constrast the mean induced activity from a group of 6 critically ill children with evidence of capillary leak syndrome was 3.0 ± 1.1 (p<.001). No activity was demonstrated in non-induced PMNs from any group. No differences in induced enzyme activity were appreciated between venous and arterial blood samples. Such findings may demonstrate the phenomena of desensitization of previously in vivo activated neutrophils to additional stimulation, and may represent a host defense which minimizes autoinjury.

5,372

Scientific Abstracts

null

5,373

Bone and Soft Tissue Pathology

null

5,374

Genitourinary

null

5,375

Scientific Abstracts

null

5,376

Pathobiology

null

5,377

1347 Non Invasive Ventilation in Pediatric Intensive Care Unit

Objective: The aim of this study was to investigate the benefit of the Non Invasive Ventilation (NIV) in children admitted to the Pediatric Intensive Care Unit (PICU). Methods: We studied 22 children supported by NIV, aged 1 month to 15 years. The duration of the study was 4 years (January 2006- December 2009). The total number of admissions to ICU during this period was 759 (2,9% supported by NIV). The causes of the respiratory failure in these children supported by NIV were: chronic diseases-infection (n=11; 50%), neuromuscular diseases (n=4; 18,18%), renal transplantations-immunosuppression (n=3; 13,63%), leukemias (n=2; 9,09%), respiratory infections (n=2; 9,09%). We selected the Biphasic Ventilation mode (Bi-Vent) by facial mask, because our patients were in severe respiratory distress. The parameters in this mode were as follow: PIP: 10-16 cmH2O and PEEP 6-12 cmH2O. The mean duration of NIV was 4 days (3 hours to 14 days). Results: Facial mask was well tolerated and with no injuries from her use. Results showed that 19 patients (86,36%) recovered and 3 patients (13,63%) died because of their underlying disease and not from the respiratory failure. Two of our patients continued the NIV ventilation as home care treatment. Conclusions: NIV support of respiratory failure is a very useful tool in the pediatric intensivists' hands because it is good alternative to mechanical ventilation. It is well tolerated, reduces the need of sedation and the PICU stay in these patients.

5,378

CEFOTAXIME IN THE TREATMENT OF BACTERIAL MENINGITIS

We evaluated the efficacy of cefotaxime in the treatment of bacterial meningitis and the diffusion of the drug into CSF. Eleven children(9 days to 5 yrs) with meningitis due to H. influenzae (7 cases), S. pneumoniae(2) , group B streptococcus (1) , and Salmonella sp.(1), were treated with 40 mg/kg of IV cefotaxime q6hrs. Cefotaxime levels were determined by HPLC. The mean cefotaxime plasma level 3 hrs after a dose early in the treatment was 14.1 mg/L(range 5.1-42.2 mg/L), and the mean CSF level was 3.9 mg/L(0.7-16.6 mg/L). The mean CSF diffusion rate was 26.4%. At the end of treatment, the mean plasma level was 7.9 mg/L(1.5-13.6 mg/L) and the mean CSF level was 1.23 mg/L(0.5-3.1 mg/L) representing a mean diffusion rate of 21.9%. Cefotaxime MBC for the infecting organisms ranged between 0.015 mg/L and 0.25 mg/L. CSF was bactericidal to the infecting organisms at dilutions between 8 and 256. The CSF diffusion correlated positively with the cefotaxime plasma level (r=0.86), CSF protein (r=0.63), CSF leukocyte count (r=0.61) and negatively with CSF sugar (r=-0.37).All patients responded well to treatment with no apparent sequelae. Serial levels were also determined in 5 infants with ventriculostomies. Following a single dose of 40 mg/kg, the mean cefotaxime CSF levels (and mean plasma levels) were 6.6 mg/L(28.4 mg/L) at 2 hrs, 5.7 mg/L(8.9 mg/L) at 4 hrs, and 4.5 mg/L (1.8 mg/L) at 6 hrs. Cefotaxime diffuses sufficiently and consistently into CSF. Further assessment of its efficacy in the treatment of childhood meningitis is warranted.

5,379

Infectious Disease Pathology

null

5,380

Physicians Poster Abstracts: EBMT 2012

null

5,381

President’s Plenary Session

null

5,382

Bone and Soft Tissue Pathology

null

5,383

1348 Influenza a H1N1 Virus Infection in a Pediactric Intensive Care Unit

Background: the main form of clinical presentation in critically ill patients with H1N1 infection is rapidly progressive respiratory failure, shock, neurological involvement and renal failure. Children with comorbidity and aged < 2 years are at particular risk. Methods: a descriptive, retrospective study on the clinical presentation and management of patients with H1N1 infection was performed in a Pediatric Intensive Care Unit (PICU). All children admitted in PICU of Coimbra's Pediatrics Hospital (CPH) were described, from July 15(th) to November 30(th) of 2009. Results: during this period, 241 children with laboratory confirmation of H1N1 infection were observed in CPH, of whom 38 (16%) required hospitalization, 4 (1.7%) in PICU-CPH. The age ranged from 4 months to 21 years. Three patients had previous co-morbidities. All met clinical criteria for H1N1 infection and were admitted with respiratory distress (4), rapidly progressive and evolution to ARDS (2), associated with shock (2) and lethargy (2). Three patients required mechanical ventilation (conventional and high-frequency oscillatory ventilation); the duration ranged between 4-12 days. Two patients received intravenous catecholamines support, two developed acute renal failure and two had pancytopenia. There were two bacterial coinfections. All received treatment with oseltamivir. Length of PICU stay ranged from 5-22 days, with a favorable outcome in all cases. Conclusion: in the 1st peak of H1N1 outbreak, 10% of the hospitalized children required PICU admission. Despite severe respiratory disease and multiple organ dysfunction, a good outcome was achieved, with no mortality.

5,384

1346 Flutisane Propionate in Prevention of Rhynitis Alergica with Children

Introduction: In childhood rhynitis alergica is medical and social problem. The nasal mucous membrane first gets in touch with a lot of causes, including causes of allergy. Objective: Improvement of quality of the life with children who are treated with Fluticasone propionate. Material and Methods: We processed the data from medical records of 58 children on the age of 6 and 12 years in the period of 2 years (2008 - 2009), and 43 children from them were put on prevention with Fluticasone propionate. For processing the data we used analytic and descriptive method. Results: We processed 58 cases with rhynitis alergica proved with: skin tests or RIDA screen tests, total IgE, eosinophyles in nose and drainage secretion. 15 children were put only on symptom's therapy, and 43 children were put on therapy with Fluticasone propionate in a period of a few months. With 9 children rhinitis alergica was followed by conjuctivitis alergica and they get antihistaminic medicaments. All children that were put on prevention had minimal symptoms of Rhynitis and they had normal physical activities and attend a school regularly. Conclusion: Suitable and therapy on time allows normal and healthy life and free activity with children who have proved rhynitis alergica.

5,385

Scientific Abstracts

null

5,386

Infectious Disease Pathology

null

5,387

Scientific Program & Abstracts: 57™ Annual Meeting March 24–27, 2010

null

5,388

Scientific Abstracts

null

5,389

Design and application of the method for isolating magnetotactic bacteria

A simple apparatus was designed to effectively isolate magnetotactic bacteria from soils or sediments based on their magnetotaxis. Through a series of processes including sample incubation, MTB harvesting, isolation, purification and identification, several strains of bacteria were isolated from the samples successfully. By Transmission Electron Microscopy (TEM) and Energy-Dispersive X-ray Analysis (EDXA), these bacteria were certificated to be magnetotactic bacteria. The phylogenetic relationship between the isolated magnetic strains and some known magnetotactic bacteria was inferred by the construction of phylogenetic tree based on 16SrDNA sequences. This apparatus has been proven to have the advantages of being inexpensive, simple to assemble, easy to perform and highly efficient to isolate novel magnetotactic bacteria. The research indicated that the combined approach of harvesting MTB by home-made apparatus and the method of plate colony isolation could purify and isolate magnetotactic bacteria effectively.

5,390

A GMC Oxidoreductase GmcA Is Required for Symbiotic Nitrogen Fixation in Rhizobium leguminosarum bv. viciae

GmcA is a FAD-containing enzyme belonging to the GMC (glucose-methanol-choline oxidase) family of oxidoreductases. A mutation in the Rhizobium leguminosarum gmcA gene was generated by homologous recombination. The mutation in gmcA did not affect the growth of R. leguminosarum, but it displayed decreased antioxidative capacity at H(2)O(2) conditions higher than 5 mM. The gmcA mutant strain displayed no difference of glutathione reductase activity, but significantly lower level of the glutathione peroxidase activity than the wild type. Although the gmcA mutant was able to induce the formation of nodules, the symbiotic ability was severely impaired, which led to an abnormal nodulation phenotype coupled to a 30% reduction in the nitrogen fixation capacity. The observation on ultrastructure of 4-week pea nodules showed that the mutant bacteroids tended to start senescence earlier and accumulate poly-β-hydroxybutyrate (PHB) granules. In addition, the gmcA mutant was severely impaired in rhizosphere colonization. Real-time quantitative PCR showed that the gmcA gene expression was significantly up-regulated in all the detected stages of nodule development, and statistically significant decreases in the expression of the redoxin genes katG, katE, and ohrB were found in gmcA mutant bacteroids. LC-MS/MS analysis quantitative proteomics techniques were employed to compare differential gmcA mutant root bacteroids in response to the wild type infection. Sixty differentially expressed proteins were identified including 33 up-regulated and 27 down-regulated proteins. By sorting the identified proteins according to metabolic function, 15 proteins were transporter protein, 12 proteins were related to stress response and virulence, and 9 proteins were related to transcription factor activity. Moreover, nine proteins related to amino acid metabolism were over-expressed.

5,391

The polymerase chain reaction and pathology practice

Pathology practice is increasingly augmented with molecular tests for improved diagnostics and patient management. The polymerase chain reaction (PCR) is foremost amongst these techniques. This review explains the principles of PCR and the methodological factors that contribute to a successful assay. Key PCR technique variations, such as reverse transcription (RT)-PCR and quantitative real-time (q) PCR, are described and an overview is provided of how PCR products are analysed. The review includes examples of PCR usage in clinical practice for the detection of infectious and genetic diseases, for tumour diagnostics and in molecular forensic applications such as specimen identity confirmation.

5,392

News in Brief

null

5,393

Rodent Diagnostic Testing

Clinical medicine is an important part of scientific medicine that is all too often neglected when treating rodents and small mammal pets. As with more traditional pets, a progressive diagnostic regimen should include a thorough history, clinical signs, physical examination, and laboratory findings.

5,394

The American Organization of Nurse Executives and Global Citizenship

Globalization is impacting many aspects of American society, and nursing has especially been impacted over the past few decades. Global issues such as nurse migration, pandemic infections, natural disasters, man-made disasters, and geopolitical unrest have made it clear that no nation can remain isolated and unaffected by world events and trends. With these facts, the American Organization of Nurse Executives' (AONE) leaders and members increasingly understand that leaders along with their communities and health care organizations work in all arenas, from local to national and international.

5,395

Paraplegia in a Domestic Ferret (Mustela Putorius Furo) Secondary to Metastatic Adrenocortical Carcinoma with Myxoid Differentiation

Neurologic disease is a common presentation of domestic ferrets (Mustela putorius furo) with infectious, neoplastic, and traumatic etiologies documented. Adrenocortical neoplasia is also well documented in domestic ferrets, with metastatic lesions rarely described. This case report describes an abnormal presentation of adrenocortical adenocarcinoma with myxoid differentiation and subsequent metastasis to the spinal cord and vertebral bodies, resulting in hind limb paraplegia in an adult spayed female ferret.

5,396

Systemic Infection Due to Candida parapsilosis in a Domestic Ferret (Mustela putorius furo)

An 18-month-old castrated male ferret (Mustela putorius furo) was presented to the veterinary hospital for acute collapse but died despite initiation of emergency treatment. The body was submitted for a complete postmortem examination. The pathologist determined the ferret was suffering from severe necrotizing encephalitis, necrogranulomatous mediastinal lymphadenitis, and ulcerative dermatitis attributable to systemic Candida parapsilosis. This is the first report of systemic Candida parapsilosis in a ferret.

5,397

Current Approach to Rodents as Patients

Rodent species are routinely presented to veterinary hospitals for wellness checks and different illnesses. When rodents are presented to the veterinarian for diagnosis and treatment, they deserve the same thorough approach that any other domestic species receives. The purpose of this article is to provide readers a review of the current information regarding examination, diagnosis, and treatment of some of the most common conditions for which rodent patients are presented. This article will cover 5 of the most common rodent species presented to veterinarians: guinea pigs, chinchillas, rats, mice, and hamsters.

5,398

Technology confronts SARS

null

5,399

Respiratory pharmacology: In defense of the lung: innovations to bolster or prevent acute and chronic lung diseases

null