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253,052,164 |
{
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"DOI": "10.1080/09500839.2022.2134938",
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|
ABSTRACT This study aimed to prepare a composite of the high-entropy alloy from the Al-Cr-Fe-Mn-Mo system reinforced by in-situ formed carbides using powder metallurgy techniques. The alloyed powder was prepared by mechanical alloying in ball-mill devices from pure elemental powders with the addition of a process control agent, namely stearic acid. Then, the alloyed powder was consolidated by hot-press sintering. The structure and microstructure of powder and bulk samples were investigated. The mechanical properties of the bulk sample were evaluated. The investigations revealed two bcc phases in the mechanically alloyed powder. The powder annealing at 950°C triggered the phase transformations, which led to the formation of the multielement matrix bcc phase (a = 2.91 Å) reinforced by two carbides molybdenum-rich M6C (a = 11.15 Å) and chromium-rich M23C6 (a = 10.66 Å). A similar composite structure was present in the bulk sample. The investigations suggested that the primary carbon source for carbide formation was the process control agent – stearic acid. The produced bulk composite revealed promising mechanical properties, such as very high hardness up to 1223 ± 99 HV2 and Young’s modulus of 246 ± 10 GPa.
|
2022-12-25T02:07:42.784Z
|
182,243,873 |
{
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"DOI": "10.26740/JEPK.V7N1.P45-54",
"MAG": "2945935299",
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"license": null,
"status": null,
"url": null
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|
This study aimed to evaluate the performance of employees after the implementation of the remuneration policy to the Higher Education and identify the reward policy and performance patterns with the pattern payroll employee remuneration and employee satisfaction levels. This study uses secondary data from the financial statements and the primary data in the form of interviews using questionnaire with the selected respondents in the sample, the academic staffs who have earned a salary based on the pattern of a single salary. The results showed that the financial performance in the achievement of 90.11% of payroll pattern showed a good indicator, but there are 0.89% of the budget that is not absorbed, which means the percentage of the expected performance can not be achieved. Analysis of the performance behavior indicate that there are changes in the behavior of post-implementation performance of the employee remuneration. Variance test results indicate that there are significant differences in the pattern of implementation of the remuneration in universities in Indonesia, which is indicated by the indicator system and the implementation of remuneration policies
|
2022-02-08T12:50:09.637Z
|
226,378,246 |
{
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"ArXiv": null,
"DOI": "10.33693/2313-223x-2020-7-2-71-78",
"MAG": "3093682547",
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|
This computational and experimental work is dedicated to the development of promising designs of vehicle drive shafts made of polymer composite materials. The paper analyzes the existing models of drive shafts vehicles and substantiates the use of a carbon-fiber drive shaft with titanium tips. A manufacturing technology for such a product is also presented. Evaluation of structure performance under the action of ultimate loads was carried out by the finite element method considering anisotropic properties of reinforced materials. Prototypes of composite drive shafts were produced for further laboratory tests. According to the tests results, the drive shafts withstands a greater torsional moment than the calculated one. As a result, it was decided to install them on a racing vehicle for carrying out field tests. During the field tests of the composite drive shaft, the mounting structure between titanium tip and composite tube was destroyed. During the full-scale tests there were no loads exceeding 60% of the calculated ones, therefore, the main cause of structural failure is fatigue failure. The next stage of the research was the development of a design that is resistant to long-term cyclic loads and has sufficient reliability. This design was designed, manufactured and tested in the framework of field tests.
|
2022-01-27T08:24:31.006Z
|
199,629,239 |
{
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"ArXiv": null,
"DOI": "10.29252/sjimu.27.2.30",
"MAG": "2964072348",
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"license": "CCBY",
"status": "GOLD",
"url": "http://sjimu.medilam.ac.ir/files/site1/user_files_44b4b4/hasanvand121-A-10-4358-1-f9e8ab5.pdf"
}
|
Introdaction: Lipid metabolism disorders, especially raised levels of cholesterol and triglycerides increases the risk of atherosclerosis. This study aimed to investigate the effect of training type including submaximal continuous and high-intensity interval training on hepatic gene expression of Apolipoprotein A ‐ I, and Apolipoprotein A ‐ II in male Wistar rats. Materials & Methods: This experimental study conducted on 24 male Wistar rats with 8 weeks of age and weight range of 200-250 g. They were randomly assigned into three groups of control (n=8), high-intensity interval training (n=8), and continuous submaximal training (n=8). High-intensity interval training protocol included 30-min interval running 3 days a week for 8 weeks (each interval took 4 min with 85-90% of VO2max and 2-min active recovery with 50-60% of VO2max). In addition, submaximal continuous training group (30-60 min) was subjected to 50-55% intensity activity with maximum oxygen consumption. Finally, gene expressions of Apolipoprotein A ‐ I and Apolipoprotein A ‐ II were measured in this study. study showed an increase in the gene expressions of Apolipoprotein A ‐ I in the high-intensity interval (P=0.034) and continuous submaximal training groups (P=0.047), compared to the control group. Moreover, the results of the Bonferroni post-hoc test showed that there was no difference between high-intensity interval and continuous submaximal training groups (P=0.9). In addition, the results of this study showed that there was no significant difference among the three groups in terms of the gene expression of Apolipoprotein A ‐ II. Discussion & Conclusions: High-intensity interval and continuous submaximal training can play important roles in reducing cardiovascular disease risks, such as atherosclerosis. This is done by increasing hepatic gene expression of Apolipoprotein A ‐ I and the main factor taking cholesterol from the liver and ultimately the high-density lipoprotein receptor.
|
2022-09-10T18:17:36.068Z
|
32,895,136 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1056/NEJM197207202870303",
"MAG": "2020064961",
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"url": null
}
|
Abstract The removal of 250 to 750 ml of blood over one to three weeks' time from nine normal nonsmoking males produced, one to three weeks later, slightly decreased hemoglobin concentrations (mean, 16.2 to 15.0 g per 100 ml). Oxygen pressure at 50 per cent hemoglobin saturation with oxygen (P50) increased from 27.9 to 29.8 torr (mean values) and was significantly correlated (p less than 0.005) with an average increase of erythrocyte glutamic oxalacetic transaminase activity from 4.4 to 5.4 U per gram of hemoglobin, indicating increased numbers of young erythrocytes. 2,3-diphosphoglycerate did not change (mean, 13.1 to 13.0 μmoles per gram of hemoglobin). The improved oxygen unloading afforded by the increased P50 thus seems to have more than compensated for the reduced hemoglobin concentration so that cardiac output could decrease and still maintain an unchanged normal mixed venous oxygen pressure.
|
2022-09-15T04:45:51.581Z
|
150,537,593 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4324/9781315582801-8",
"MAG": "136671943",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
This paper examines state protection as applied to the Roma minority group in the Czech Republic and the link to Roma refugee claimants in Canada. The paper traces measures implemented by the Czech national authorities to improve the situation of the Roma, but also continuing problems of discrimination and violence by state and non-state actors. It also describes the often weak implementation and enforcement of anti-discrimination measures by state officials and the judiciary, among which are the failure to properly investigate and hold accountable public officials, including police officers, accused of misconduct towards members of the Roma minority. The paper then examines the Canadian governmental response to the 2008–09 influx of Czech Roma refugee claimants. It argues that Canada’s response reflected broader trends among receiving states, particularly the effort to reinforce state sovereignty and territorial control, and in concert with efforts to exert greater political influence over the refugee determination process, the response resulted in the weakening of Canada’s obligations under the international refugee regime. This work was prepared as part of a project on Migration and Asylum in Europe and EU-Canada Relations, funded by the European Commission, Directorate-General for External Relations, Relations with the US and Canada. The project aims at providing a better understanding of the conceptual, political, sociological and legal elements and dilemmas characterising the development of common European public responses to these issues, and their implications for the relationship between liberty and security in EU-Canada relations
|
2022-11-11T08:11:49.487Z
|
95,368,982 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1080/19443994.2015.1022807",
"MAG": "1990962956",
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},
"license": "CCBYNCND",
"status": "GREEN",
"url": "https://upcommons.upc.edu/bitstream/2117/102568/1/Article%20Reversibility%20of%20fouling-proof.pdf"
}
|
AbstractMembrane fouling is an inherent phenomenon in ultrafiltration (UF) membrane processes, making it necessary to periodically perform backwashes (BW) and chemical “cleanings in place” (CIP) to restore the initial permeability of the membrane. The objective of this study was (1) to explore systematically the effect of distinct BW-related variables (BW transmembrane pressure, duration, frequency and composition) on the reversibility of UF membrane fouling and on the permeate quality (in terms of total organic carbon, turbidity and UV absorbance) over successive filtration/BW cycles; and (2) to identify which organic fractions were most removed by the membrane and, of these, which were most detached after BW, alkaline and oxidant CIP and acid CIP episodes. For this purpose, a bench-scale outside-in hollow fibre module operated under dead-end filtration mode at constant transmembrane pressure and treating settled water from a drinking water treatment plant was employed. Dissolved organic carbon fractiona...
|
2022-11-13T17:48:01Z
|
198,657,478 |
{
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"ArXiv": null,
"DOI": "10.5937/ANEKSUB1941115V",
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|
This paper puts emphasis not only on employment problems but also on perspective of increasing employment rate in the Republic of Serbia (Serbia) in the field of circular economy. Circular economy, the 21 century concept and model, is a great chance for making employment rate higher, as well as for ecological protection and budget savings. This topic is very important for the Republic of Serbia (Serbia), candidate for the European Union (EU), and in that context greening economy is obligatory. What is one of the key measures for increasing of (green) employment is the state aid for training of employees, and strategic approach in that sense.
|
2022-12-27T05:22:57.217Z
|
140,716,204 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.13083/REVENG.V21I6.414",
"MAG": "1981780941",
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"status": null,
"url": null
}
|
The Mato Grosso state shows irregularities in rainfall patterns, requiring a climate study seeking to establish the optimum planting dates with the lowest risk of hydric deficit. Therefore, this study aimed to identify the best sowing times with less risk climate for growing of upland rice through hydro and thermal analysis of the last five crop years for the town of Tangara da Serra, MT. We used data of temperature and precipitation of the last five years (2007/2008 a 2011/2012) provided by the Instituto Nacional de Meteorologia (INMET). The times less climate risk were determined from the simulation of crop development by calculating the degree-day and by calculating the water balance proposed by Thornthwaite and Mather, comparing with the water needs for the development stages. The duration of the phases of the culture was to E/R1 50 days, 78 days and 103 days for E/R4 E/MC. Later sowings as five times (December 15) and six (December 31) increase the total cycle time, as well as the number of days to flowering. The sowing dates were more favorable to the cultivation was 5 and 6 (December 15 and December 31, respectively).
|
2022-02-09T08:56:54.976Z
|
235,751,031 |
{
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"ArXiv": null,
"DOI": "10.4103/jhrs.jhrs_241_20",
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"PubMedCentral": "8279063"
},
"license": "CCBYNCSA",
"status": "GOLD",
"url": "https://doi.org/10.4103/jhrs.jhrs_241_20"
}
|
Background: One of the causes of male fertility disorders is the exposure of oxidative stress on the human sperm. Understanding the mechanism of disturbance is important to develop a better treatment for infertile or subfertile patients. Aims: The aim of this study was to analyze the effects of hydrogen peroxide (H2O2) on human sperm quality parameters and cell survival. Settings and Design: This study used an experimental design. Materials and Methods: Sperm cells from 15 donors were washed in a Percoll gradient and dissolved in Biggers, Whitter, and Whittingham medium. Cells were incubated with H2O2 at various concentrations from 0 to 250 μM for 2 h. Sperm viability was examined by eosin assay, sperm kinetic by computer-assisted sperm analyzer, sperm penetration by cervical mucus penetration assay, and membrane integrity by hypo-osmotic swelling test. Sperm capacitation, apoptosis, and cell survival were analyzed using western immunoblotting. Statistical Analysis Used: One-way ANOVA on SPSS 21 combined with post hoc LSD test was used to analyze differences among the groups. A P < 0.05 was considered significant. Results: Sperm viability and kinetic were significantly reduced at H2O2 concentrations of 200 and 250 μM. H2O2 reduced sperm capability to penetrate cervical mucus and also damage cell membrane integrity at all concentrations used. H2O2 significantly inhibited sperm capacitation, indicated by reduced total tyrosine phosphorylation. H2O2 exposure stimulated activation of caspase 3 and significantly reduced phosphorylated AKT at all concentrations used. Conclusions: H2O2 comprehensively inhibits sperm qualities related to the capacity to fertilize oocyte, stimulates caspase activity, and inhibits cell survival.
|
2022-11-18T00:11:57.343Z
|
99,787,362 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1002/cctc.201600659",
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|
A potentially viable route for the synthesis of 3‐substituted indoles is presented herein. The methodology is based on a regioselective Rh‐catalysed hydroformylation of prepared 2‐alkyn‐1‐ylanilines. The requisite 2‐alkynylaniline substrates were prepared in high yields (>85 %) using the Pd‐catalysed Sonogashira reaction. A catalyst complex that comprises RhI(CO)(PPh3)3 and 1,2‐bis(diphenylphosphino)ethane as the ligand allowed the quantitative conversions of the alkynyl substrates with selectivities >75 % for the desired 3‐substituted indoles.
|
2022-12-11T01:26:02.229Z
|
203,180,343 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.31926/BUT.ES.2019.12.61.1.9",
"MAG": "2970562867",
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|
Differences in behaviour between generations are becoming increasingly apparent. The young generation of the moment, also known as Generation Z, distinguishes by many elements from the previous generations. The article performs a research among the students of the Faculty of Economic Sciences and Business Administration from the Transilvania University of Brașov in order to analyse some behavioural elements related to the information, acquisition and consumption of tourist products. In manifesting their tourism behaviour, Generation Z members develop attitudes of utmost relevance and importance for professionals in
|
2022-12-24T16:43:24.989Z
|
108,856,793 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.14429/dsj.15.7284",
"MAG": "1554311435",
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|
Study on distribution of dissolved oxygen is important from the point of view of productivity and structure of water masses. Water samples at about 60 stations spread over the northern Arabian Sea were collected and their oxygen content estimated. The study reveals fairly high oxygen content in surface waters off the Bombay coast and along latitude 15 degree N. Progressive lowering in depth of oxygen minimum zone from 24 degree N southwards is also noticed. Subsurface upwelling around 60 degree E, 20 degree N seems to be in progress.
|
2022-02-10T06:45:37.498Z
|
244,163,726 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.24193/subbeng.2021.1.3",
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"license": null,
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}
|
This study was carried out at the Teaching and Research Farm of the Department of Agricultural and Bio-Environmental Engineering, School of Engineering, The Federal Polytechnic, Ado-Ekiti to evaluate the water holding capacities of soil under different fertilizers. The experiment was laid out in randomized complete block design (RCBD). The treatments: control, poultry waste, biochar and urea fertilizer replicated four times were incorporated into the soil and maize seed planted. Data collected were subjected to statistical analysis. Soil samples were analyzed for moisture contents, bulk densities, particle densities and water holding capacities. Maize yield was also analyzed. The result obtained showed a significant (p< 0.05) changes in maize yield for the different fertilizers. It also shows a non-significant (p<0.05) effect on water holding capacities of the soils incorporated with different fertilizers. The study concluded that fertilizers has no effect on the water holding capacity of the soil and that poultry waste amended soil will produce higher yield.
|
2022-01-27T07:58:41.852Z
|
94,937,130 |
{
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"ArXiv": null,
"DOI": "10.1017/S0013091500033939",
"MAG": "1991712862",
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"license": null,
"status": null,
"url": null
}
|
Cayley has shown that if the family of surfaces φ(x, y, z) = λ is one of an orthogonal triad, φ satisfies a differential equation of the third order. If, however, the parameter λ is involved implicitly in the equation of the family, the condition requires modification: for example, although is one of an orthogonal triad, φ does not satisfy Cayley's equation.
|
2022-07-27T05:55:58.629Z
|
24,233,963 |
{
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"ArXiv": null,
"DOI": "10.7748/ns.30.16.41.s45",
"MAG": "2224250278",
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|
AIM
To explore activities, interactions and behaviours during the first appointment in adult care for young people with cystic fibrosis.
METHOD
Observational data were collected at 12 first appointments. Framework analysis was applied to written field notes.
FINDINGS
Interaction enablers and interaction barriers were identified in the data. Practitioners endeavoured to be holistic, addressing personal as well as physical factors. This involved broaching individuals' interests, self-disclosure and humour. Various activities were accomplished. The role of parents in the continued management of cystic fibrosis was not raised at first appointments.
DISCUSSION
Practitioners require clear objectives for first appointments in adult care to ensure young people adapt to this new healthcare setting. Young people should be prepared for transfer so they can respond to and ask questions, and parents should be assisted to relinquish control of their child's condition. Conclusion A modest set of objectives for the first appointment should be set to enable young people to retain information, while introducing them to a new service.
|
2022-09-02T20:46:36.816Z
|
149,261,878 |
{
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"ArXiv": null,
"DOI": "10.1093/APPLIN/AMX026",
"MAG": "2755557441",
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}
|
There is a growing awareness in methodological literature that parametric statistical tests may not be appropriate in studies with a small sample size and non-normal data (Larson-Hall and Herrington 2010; Mizumoto and Plonsky 2016). In addition, the presence of outliers or cases widely different from the rest of the data set poses serious methodological challenges: even a single extreme case can invalidate the estimated statistics in parametric methods (Larson-Hall and Herrington 2010). As Larson-Hall (2010) noted, removing outliers from the data set is undesirable for several reasons. First, such decisions are based on the researcher’s subjective opinion. Secondly, when one outlier is removed another may emerge and the subsequent removal of all outlying cases could drastically reduce the number...
|
2022-09-05T21:20:08.482Z
|
252,063,367 |
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"ArXiv": null,
"DOI": "10.3390/su141710924",
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"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2071-1050/14/17/10924/pdf?version=1662029230"
}
|
Africa is a huge continent with an area equal to 30,244,049 km2 and a population of over 1.3 bn. According to the World Energy Outlook 2021, the electrification rate for Sub-Saharan Africa is at 79% for urban areas and only 28% for the rural areas. Given the low electricity infrastructure in Africa in production, transmission and distribution as well as the very low access in rural areas, it is understood that coordinated activities must take place for both on-grid and off-grid electrification activities, if the targets set for 2030 are to be met. This paper aims to present the challenges faced in the harmonization of the electricity markets in Africa due to the complexities of political continental integration, as well as continental economic integration, by performing a review of the progress made so far. It is one of the few efforts that have aimed to present in a single document the institutional framework of the electricity sector in Africa, and how these institutions collaborate in order to form and deploy policies at the continental and regional levels, affecting ultimately the deployment of policies at the national level. It also presents the current status of the continental electricity market policy framework activities towards the achievement of the 2030 goals in line with Agenda 2063, and the crucial role the African Single Electricity Market (AfSEM) is set to play. Finally, it provides lessons learnt and recommendations on facilitating the way forward in terms of the institutional actors’ collaboration, both for Africa and globally, in terms of developing regional energy markets.
|
2022-09-09T04:38:41.565Z
|
253,006,060 |
{
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"DOI": "10.55251/jmbfs.9270",
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},
"license": "CCBY",
"status": "GOLD",
"url": "https://office2.jmbfs.org/index.php/JMBFS/article/download/9270/3317"
}
|
The main chemical parameters such as content of sugar (glucose and fructose), organic acid (total acids, malic and tartaric acids), total phenolics and the antioxidant activity in 9 dry white wines with PDO of 3 varieties (Pinot Blanc, Riesling, Sauvignon blanc) from 3 countries (Slovakia, Hungary, Austria) were studied in this work in order to identify possible differences in their quality affected by geographical origin. The wine samples were examined by the FTIR and spectrophotometry methods (TPC and DPPH). As supporting parameters, alcohol and glycerol content were used and sensory evaluation of wines was performed. For the statistical evaluation were used ANOVA and PCA methods. Austrian wines in general, were characterized by high glucose and fructose content, high TPC and antioxidant activity. Higher results of these parameters are characteristic especially for the Austrian varieties Pinot blanc and Sauvignon blanc which originated from the same wine-region in Austria. Sauvignon variety from Slovakia was characterized by higher total acid content, especially in the case of tartaric acid. Statistical evaluation was helpful to show several differences, especially in the case of PCA application. Just Riesling variety from all countries of origin was so similar that it was not possible to be strictly distinguished using PCA. Wines from Hungary (Sauvignon and Pinot blanc) showed higher content of alcohol and glycerol, as they are produced by the sugar fermentation. Wines from Slovakia were evaluated as the best samples among selected ones within their sensory evaluation.
|
2022-10-21T14:59:21.738Z
|
253,404,355 |
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"DOI": "10.5210/fm.v27i11.12744",
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},
"license": "CCBYNCSA",
"status": "HYBRID",
"url": "https://doi.org/10.5210/fm.v27i11.12744"
}
|
Existing research has begun to document some of the troubling links between COVID-19 news consumption and emotional and psychological well-being, but precisely which sources of news are more likely to be related to such phenomena is still relatively unknown. Given the greater likelihood of encountering disinformation, rumour and other content of dubious origin via interpersonal networks (e.g., friends and family) on social media, we might assume that this is liable to spark greater confusion, fear, panic, anxiety and other negative emotions in comparison to, say, mainstream media. But through a nationally representative survey of U.K. news users we show that, on the whole, there were no significant statistical or practical differences in audiences’ emotional responses to the news between those who rely on social media as their primary source for COVID-19 news, and those who rely on other sources of news. Rather, we observe similarly high levels of negative and positive emotional responses for all types of news source. Findings are discussed in light of ongoing debates around news sources, emotions and public health.
|
2022-11-11T08:15:48.968Z
|
84,422,420 |
{
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"DOI": "10.1163/156853895X00190",
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|
Water fluxes and daily energy expenditure (DEE) of Gallotia galloti, G. stehlini and G. atlantica, were estimated over a three-year period using the doubly-labelled water (DLW) method. Water influx varied little between seasons and between sexual categories. Juveniles tended to have higher water fluxes in spring in all three species; after a dry period the water turnover tended to decrease for all sexes in G. galloti and G. stehlini, whereas little variation was observed for G. atlantica. The average water influx, combined for all periods, was 46.27, 50.97 and 38.20 ml H 2 O.kg -1 d -1 for the three species respectively; only the last value differs significantly from the remaining two. The mean DEE, for all periods combined, were 189.7, 179.4 and 146.5 J g -1 d -1 for the three species respectively. As for water turnover, only the value for G. atlantica differed significantly. These data suggest that: G. atlantica may be better adaptated to maintain homeostasis during dry periods and that differences in interspecific DEE can also be explained by others factors than differences in habitat, climatic conditions, daily profiles of activity or body temperatures. We suspect that the incidence of intraspecific competition has more importance in G. atlantica than in the two other species.
|
2022-12-16T01:17:47.721Z
|
32,906,328 |
{
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"DOI": "10.1089/NEU.1994.11.447",
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|
Patients with head injury must overcome central as well as peripheral metabolic insults. In addition to specific tissue damage to the brain, a cellular biochemical cascade occurs that can negatively affect organ function, cause a systemic response to injury, and may cause secondary tissue injury. The metabolites involved in this cascade are numerous and complex. Cytokines are important cell-to-cell communication mediators during injury. It is speculated that cytokines, such as interleukin 1 (IL-1), interleukin 6 (IL-6), tumor necrosis factor (TNF), and interleukin 8 (IL-8), which are found in elevated amounts in both human and basic trials after head injury, play a role in the cellular cascade of injury. Some of the metabolic events produced by small doses of cytokine infusion in animals, as well as humans, include fever, neutrophilia, muscle breakdown, altered amino acid metabolism, depression of serum zinc levels, production of hepatic acute phase reactants, increased endothelial permeability, and expression of endothelial adhesion molecules. These are all known sequelae of severe head injury. Cytokines have also been implicated in organ failure. Infusion of cytokines in basic science trials revealed that organ functions of the gut, liver, and lung are negatively altered by high-dose cytokine infusion. Infusion of certain cytokines has been shown to cause death of brain cells, increase blood-brain barrier permeability, and cause cerebral edema. This suggests that cytokines may also play a role in the sequelae of organ demise. These effects of cytokines have been attenuated in basic trials by blocking the initial signaling system of cytokines or by decreasing serum cytokine activity. We hypothesize that cytokines that are elevated after head injury play a role in the pathology of injury, including altered metabolism and organ demise.
|
2023-01-01T17:21:53.383Z
|
110,466,824 |
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"DOI": "10.1117/12.836382",
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},
"license": null,
"status": null,
"url": null
}
|
Infrared imaging fuze is invulnerable to the electromagnetic interference, and it has the ability to recognize the local image of the target. At present, the infrared imaging fuze technology has become one of the key technologies which perform the target detection and the ignition of the warhead in the complex tactical environment. According to the scanning mechanism of the infrared imaging fuze, based on the analysis of features of the infrared image of tank target, this paper presents a feature extraction method based on knowledge to recognize infrared gray image. The geometric features and gray level features are extracted. The geometric features include the corner features and angular features. The corners of the image are extracted through the SUSAN corner detection principle,the angular feature is extracted by Freeman chain code. The hot-zone gray feature is extracted by the template matching and image binarization principle. In order to realize real-time recognition, this paper uses FPGA technology to achieve recognition circuit. The experiments show that the recognition method has a certain anti-interference ability.
|
2022-02-27T12:03:13.547Z
|
216,171,602 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1364/josab.389601",
"MAG": "3013745370",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://backend.orbit.dtu.dk/ws/files/212027365/josab_37_5_1494.pdf"
}
|
Dynamical thermo-optic instabilities in asymmetric dual-core fiber amplifiers are investigated by numerical simulations. A coupled-mode model capable of describing the asymmetric dual-core structure is derived, and structures with various levels of refractive-index asymmetry from $ {{10}^{ - 6}} $10−6 to $ {{10}^{ - 4}} $10−4 are studied. The most viable route to avoid thermally induced power signal field fluctuations is found to be core decoupling via large separation and strong refractive-index asymmetry. A design criterion for this strategy to be effective is suggested based on the numerical results.
|
2022-10-14T00:32:09.453Z
|
4,933,671 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1159/000488209",
"MAG": "2799436565",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This cross-sectional study assessed the relationship between fixed orthodontic treatment duration and caries activity. Two hundred and sixty 10- to 30-year-olds were divided into 4 groups (n = 65): no fixed orthodontic appliances (G0), orthodontic treatment for 1 year (G1), 2 years (G2), or 3 years (G3). Orthodontic treatment duration was significantly associated with active caries: prevalence was 1.5% for G0, 27.7% for G1, and 72.3% for G2 and G3; the median number of lesions was 0 for G0 and G1 and 2 for G2 and G3. No differences were observed between G2 and G3. The longer the duration of orthodontic treatment, the higher the prevalence/extent of active caries lesions.
|
2022-11-30T19:38:46.907Z
|
136,764,783 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1098/rspa.2005.1447",
"MAG": "2021919969",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
An effective interphase model (EIM) and a uniform replacement model (URM) are proposed to study the effect of an inhomogeneous interphase with varying elastic properties in the radial direction on the effective elastic moduli of composites reinforced by fibres/spheres. The central idea of these models is to convert a fibre/sphere with its interphase into a two-phase or homogeneous fibre/sphere. Then, the strain energy changes can be obtained using the three-phase model or Eshelby's solution. Detailed comparisons with the finite-element method (FEM) results of the strain energy changes for various possible material combinations of fibre/sphere, interphase and matrix are carried out to check the validity of the two models. Moreover, the other two existing models, the uniform interphase model (UIM) and differential replacement model (DRM), are compared with the new ones. It is shown that the validity of these analytical models depends on the material combinations. The EIM can be valid for general cases, while the simple URM is only valid for some cases. The validity ranges of the two existing models lie between those of the two new ones. Finally, the expressions of the effective elastic moduli of composites involving an inhomogeneous interphase are given by combining these models and the Mori–Tanaka method. The application of these expressions is illustrated through three examples and further comparisons with FEM results are also given.
|
2022-12-18T11:57:31.428Z
|
209,407,355 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/microorganisms7120700",
"MAG": "2995772298",
"PubMedCentral": "6956236"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2076-2607/7/12/700/pdf"
}
|
Kombucha tea is a refreshing beverage that is produced from the fermentation of tea leaves. In this study, kombucha tea was prepared using 1% green tea, oolong tea, and black tea, and 10% sucrose with acetic acid bacteria and yeast. The pH values of the kombucha tea were found to be in a range of 2.70–2.94 at 15 days of fermentation. The lowest pH value of 2.70 was recorded in the kombucha prepared from black tea. The total acidity of kombucha prepared from black tea was the highest by 16.75 g/L and it was still maintained after heat treatment by boiling and after autoclaved. Six organic acids: glucuronic, gluconic, D-saccharic acid 1,4-lactone, ascorbic, acetic, and succinic acid in kombucha tea were detected by HPLC with the optimization for organic acids detection using isocratic elution buffer with C18 conventional column. The highest level of organic acid was gluconic acid. Kombucha prepared from green tea revealed the highest phenolic content and antioxidation against DPPH radicals by 1.248 and 2.642 mg gallic acid/mL kombucha, respectively. Moreover, pathogenic enteric bacteria: Escherichia coli. E. coli O157:H7. Shigella dysenteriae, Salmonella Typhi, and Vibrio cholera were inhibited by kombucha and heat-denatured kombucha with diameter of the inhibition zones ranged from 15.0 ± 0.0–25.0 ± 0.0 mm. In addition, kombucha prepared from green tea and black tea demonstrated toxicity on Caco-2 colorectal cancer cells. Therefore, kombucha tea could be considered as a potential source of the antioxidation, inhibition of pathogenic enteric bacteria, and toxicity on colorectal cancer cells.
|
2022-12-25T17:51:33.608Z
|
238,690,280 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.34720/8TEX-VE86",
"MAG": "3196048352",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Esta obra es un proyecto llevado a cabo por el Grupo de Investigacion Escenica (GIE), perteneciente a la Universidad de Chile y el Liceo de Adultos Herbert Vargas Wallis, ubicado dentro de la ex penitenciaria del Santiago, donde aborda la labor docente de acompanar a sus alumnos en la finalizacion de estudios de educacion basica y media.
La presente publicacion contiene una serie de escritos en torno a Arte y Educacion en contexto de reclusion, a traves de las palabras del equipo directivo y docente del liceo y de los miembros del GIE, Con esto se persiguen dos objetivos principales: presentar reflexiones respecto al tema en cuestion y generar registro fisico y documental de la importante practica docente que se realiza en este contexto.
Este proyecto esta enmarcado dentro de los Laboratorios de Arte Colaborativo, instancia promovida por la Vicerrectoria de Investigacion y Desarrollo de la Universidad de Chile, espacios gracias a los cuales fue posible la publicacion de este escrito.
|
2022-01-23T02:32:49.439Z
|
120,391,510 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/0253-6102/36/5/620",
"MAG": "1986999093",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We further calculate the dependence of on in high magnetic fields, where denotes susceptibility and is temperature, using our previous research work — Green function's decoupling approximate approach, for the one-dimensional ferrimagnetic chain with alternating spins 1 and 1/2. We find a linear correlation in certain range of magnetic field between the temperature of maximum and the magnetic field. Moreover, we simply analyze its physical meaning by our approach.
|
2022-07-31T09:06:42.769Z
|
143,713,435 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/09596419308720994",
"MAG": "2004548422",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The relations between Muslims and Christians of Cyprus today are tense and this situation is exploited by politicians and historians at the expense of ordinary Cypriots. Especially after July 1974, when the Turkish army intervened to prevent the annexation of the island to Greece by a coup d'etat led by Nicos Sampson, a Greek general, the Greek Cypriots have lived in the south and the Turks in the north of the island. Here, the author aims to portray a different picture of the relations between the two communities from that given in the recent historiography of the island. It is shown that at the beginning of the eighteenth century, contrary to the picture often given, life was not intolerable for Greek Cypriots, and the two religious communities enjoyed much in common and collaborated in almost every aspect of daily life.
|
2022-08-06T07:08:25.515Z
|
59,496,382 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.19044/ESJ.2014.V10N10P%P",
"MAG": "1913694567",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
After the World War II mankind entered a new phase of international relations development. It is characterized by extension of international economic, political and cultural collaboration; intensification of internationalization and globalization processes, further more world community tends to greater integration, greater foreseeability, and growth of organization and development control mechanisms. In this job the accent is laid upon analyses of regional integration, which is one of the key methods of solving globalization challenges. Before dwelling upon integration in Africa, it is necessary to define the notion of integration and globalization, analyze the way they intercourse and trace the way globalization process influences the integration process in Africa.
|
2022-09-04T02:55:08.724Z
|
43,401,668 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1053/j.gastro.2012.01.050",
"MAG": "1987881573",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "http://www.gastrojournal.org/article/S0016508512003010/pdf"
}
|
Question: A 9-year-old girl presented with a history of recurrent episodes of prolonged (about 15 days) fever associated with mild and occasional abdominal pain that have been going on for the past 8 months. Symptoms resolved spontaneously and the patient was completely asymptomatic during periods of apyrexia. Her past medical history was normal. During acute episodes, the physical examination was unremarkable except for fever, spiking usually in the afternoon or evening, with shivering. Routine laboratory investigations showed an important increase of the erythrocytes sedimentation rate (ESR; 68 –78 mm/h; reference range, 0 –20) and only a mild elevation of C-reactive protein (CRP; 4 –5 mg/dL; normal value, 0.5 mg/dL). Complete blood count, liver function tests, electrolytes, immunoglobulins, and other serum chemistries were normal. Blood and urine cultures were negative. Mantoux test was negative. Chest x-ray, abdominal ultrasonography, and echocardiography were unremarkable. Viral and neoplastic markers were negative, documenting only a previous Epstein–Barr virus infection. There were no atypical cells or blasts in the peripheral blood smear. Urinary vanillin-mandelic and homovanillic acid levels were also normal. Autoantibodies tested (ANA, ANCA, Anti-DNA) were negative. To further investigate the source of abdominal pain, a computed tomography of the abdomen was performed (Figure A, B). What is the most likely diagnosis? See the GASTROENTEROLOGY web site (www.gastrojournal.org) for more information on submitting your favorite image to Clinical Challenges and Images in GI.
|
2022-11-11T08:04:02.862Z
|
22,034,767 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1107/S1600536811016370",
"MAG": "1893234237",
"PubMedCentral": "3120552"
},
"license": null,
"status": null,
"url": null
}
|
The title compound, C13H13NO4S, is a racemic mixture of enantiomers. Short intramolecular contacts between sulfonyl O and ester carbonyl C atoms are observed [C⋯O = 2.881 (1), 2.882 (1) and 2.686 (1) Å], indicating the possibility of donor—acceptor interactions between these groups. The dihedral angle between the phenyl and cyclopropyl rings is 79.3 (1)°.
|
2022-11-11T08:18:01.472Z
|
149,419,161 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21831/HSJPI.V4I1.11282",
"MAG": "2765245554",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Penelitian ini bertujuan untuk mengetahui: (1) hubungan antara keterlibatan dalam organisasi BEM dengan keterampilan berpikir kritis, (2) hubungan antara keterlibatan dalam organisasi dengan sikap demokratis, dan (3) hubungan antara keterampilan berpikir kritis dan sikap demokratis mahasiswa STKIP Weetebula. Penelitian ini merupakan penelitian korelasi. Jumlah populasi 30 orang pengurus BEM STKIP Weetebula. Data diperoleh melalui penyebaran angket pada 30 mahasiswa tentang keterlibatan organisasi dan sikap demokratis, serta angket observasi untuk mengetahui keterampilan berpikir kritis. Teknik analisis data yang digunakan adalah analisis korelasi. Uji hipotesis adalah uji parametric dengan rumus korelasi product moment untuk menguji hubungan antara variabel, yaitu keterlibatan dalam organisasi dengan keterampilan berpikir kritis dan sikap demokratis. Hasil penelitian menunjukan bahwa terdapat hubungan yang signifikan antara: (1) keterlibatan organisasi dengan keterampilan berpikir kritis. (2) keterlibatan organisasi dengan sikap demokratis. (3) keterampilan berpikir kritis dengan sikap demokratis. Berdasarkan hasil analisis tersebut maka keterlibatan mahasiswa STKIP Weetebula dalam organisasi BEM memiliki hubungan yang signifikan dengan keterampilan berpikir kritis dan sikap demokratis. Kata kunci : keterlibatan organisasi, keterampilan berpikir kritis dan sikap demokratis mahasiswa THE RELATIONSHIP BETWEEN THE INVOLVEMENT IN THE ORGANIZATION OF STUDENTS' EXECUTIVE BODY AND THE CRITICAL THINKING SKI1LS AND DEMOCRATIC ATTITUDES OF STUDENTS Abstract This study aims to find out the relationship: (1) between the involvement in the organization of SEB and the critical thinking skills, (2) between the involvement in the organization of SEB and their democratic attitudes, and (3) between the critical thinking skills and their democratic attitudes. This research was a correlational study using the quantitative approach. It was a population study; the population comprised 30 students who were board members of SEB of STKIP Weetebula. The data were collected by distributing questionnaires on the involvement in the organizations and democratic attitudes to 30 students and those on their critical thinking skills to several lecturers. The data analysis technique was the correlation technique. The hypothesis testing employed a parametric test using the product moment correlation formula. The results of the study are as follows. (I) There is a significant positive relationship between the involvement in the organization of SEB and the critical thinking skills. (2) There is a significant positive relationship between the involvement in the organization of SEB and the democratic attitudes of students. (3) There is a significant positive relationship between the critical thinking skills and the democratic attitudes. Based on the analysis finding, the result show that the involvement in the organization of students’ executive body has significant positive relationship with the critical thinking skills and democratic attitudes of students of STKIP Weetebula of the regency of Sumba Barat Daya). Keywords: involvement in organization, students' critical thinking skills and democratic attitudes
|
2022-12-11T04:12:08.581Z
|
41,848,220 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.7547/87507315-85-4-226",
"MAG": "2058097283",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A case of osteochondrosis of the tarsal navicular in an adult is presented. The patient was not fully compliant with the recommendations of the physicians involved and, as a result, full recovery has not been accomplished. Left untreated or undertreated, Mueller-Weiss syndrome can result in severe permanent osteoarthritis of the midtarsal joint (talonavicular joint). This may result in permanent deformity and disability. Properly treated with rest and supportive therapy, the condition is self-limiting and should heal without any sequela.
|
2022-12-18T22:01:43.710Z
|
96,544,037 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1063/1.3659831",
"MAG": "2072835738",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Experimental study on dust dynamics in cryogenic plasma is presented. Dust particles are introduced into an rf discharge plasma in the vapor of liquid helium. Charged dust particles are extracted from the rf plasma into a diffused plasma closer to the surface of the liquid helium. The thermophoretic force is found to play an important role in the dynamics of dust particles.
|
2022-12-16T00:10:51.832Z
|
150,116,717 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/01.JU.0000556652.07944.34",
"MAG": "2941003863",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
INTRODUCTION AND OBJECTIVES: Renal transplant is the most desired and cost-effective therapy for patients with end stage renal disease. While a lower urinary tract cause of end-stage renal disease is not an absolute contraindication to renal transplantation, appropriate vesical storage and drainage is imperative for survival and function of the graft. Thus, careful identification of certain transplant patients for preoperative urodynamics (UDS) may prevent post-transplant urological complications and possible graft failure. METHODS: We retrospectively reviewed all patients who underwent a renal transplantation with subsequent UDS testing at our institution between January 2000 to October 2016. None of the patients had preoperative UDS. Twenty-eight patients were identified and 11 were excluded due to missing data. Information collected included demographics, past medical and surgical history, transplant indication, dialysis duration, pre-transplant urine output, reason for urological evaluation, and UDS results. Characteristics of these patients were analyzed to assess for trends that may predict post-transplant urological issues and graft compromise based on pre-transplant risk factors. RESULTS: The most common comorbidities in the cohort were hypertension (88%), diabetes mellitus (53%), coronary artery disease (41%). The most common indications for transplantation were diabetes mellitus (47%) followed by hypertension (41%). Six of the 17 patients (35%) had post-transplant urological issues resulting in potential compromise of their grafts. In order, the most common reasons for post-transplant urological evaluation in these six patients were urinary retention/incomplete emptying, recurrent urinary tract infections, elevated creatinine, and transplant hydronephrosis. Urodynamic findings in these patients revealed incomplete emptying or retention (67%), detrusor overactivity (67%), hypotonic bladder (33%), atonic bladder (33%), poor compliance (33%), and small capacity (33%). CONCLUSIONS: Our findings suggest urological evaluation with urodynamic testing is underutilized in the diagnosis, treatment and optimization of pre-existing urological conditions in order to improve graft success and avoid unforeseen problems in the pre-transplant setting. Currently, there is no consensus in existing guidelines regarding which patients should have formal urological evaluation with urodynamics before undergoing transplantation. Additional efforts in this area is necessary to improve the overall success of renal transplantations. Source of Funding: none
|
2022-12-21T06:47:27.188Z
|
31,747,191 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.23919/ITU-WT.2017.8246841",
"MAG": "2783289596",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The accelerated development of AI brings new opportunities for human life and social improvement. For promoting the holistic integration of AI and economic society and further enhance China's innovation capacity in intelligence technologies, the Chinese government has launched a major R&D program in AI, within the framework of “Science and Technology Innovation 2030”, a national science and technology strategic development plan. The goal of this program is to explore the next generation AI theory and technology, and to focus on five areas: big-data-based AI, internet-based crowd intelligence, cross-media intelligence, hybrid augmented intelligence, and autonomous-intelligent systems. Additionally, in 2008 the National Natural Science Foundation of China (NSFC) launched a major research plan on Cognitive Computing of Visual and Auditory Information (2008–2017), the total expenditure of this plan is about $27M. In this research program, autonomous vehicles have been used as an integrated verification platform for the study of new cognitive computing models. Since 2009, NSFC has held annual autonomous vehicle competitions, called Intelligent Vehicles Future Challenge (IVFC). This keynote speech will give an overview of the Chinese perspective and practice on developing AI and related connected and autonomous vehicle research activities in the last decade, It will also discuss the promising transition from cognitive intelligence towards cyber-physical-social systems (CPSS) based parallel intelligence. On the basis of parallel intelligence, parallel driving aims at offering a unified approach for synergizing connected automated vehicles as well as intelligent transportation.
|
2022-12-21T03:27:54.398Z
|
226,574,977 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.24247/ijmperdjun2020355",
"MAG": "3042956086",
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://doi.org/10.24247/ijmperdjun2020355"
}
|
1PG Student, UIE Civil Engineering, Chandigarh University, Mohali, Punjab, India 2Associate Professor, UIE -Civil Engineering, Chandigarh University, Mohali, Punjab -------------------------------------------------------------------------***-----------------------------------------------------------------------AbstractFrom decades it is common in construction to Consume natural resources. In construction industries, demand of construction materials is never come down and that is why there is need to focus on alternative construction material. If waste material like waste foundry sand, silica fume, glass powder is used as an alternative construction material then it can help to reduce the amount of disposal material. The research is conducted to compare concrete performance between conventional mix trial and a mix with addition of Waste Foundry Sand, Silica fume & Glass powder in different concrete mix trial and check how concrete behave by addition of these (Waste Foundry Sand, Silica fume & Glass powder in different concrete mix trial). By utilizing waste like waste foundry sand as a partial replacement of natural sand in concrete mix to create eco-friendly environment so that we can reduce the consumption of our natural resources. Silica fume can be replaced with cement as it reacts with calcium hydroxide that is formed in the hydration of Portland cement. The strength and durability properties are evaluated with conducting experimental study, where total of 4 concrete mix trial will be prepared and evaluate. First concrete mix trial will be made as a conventional mix trial. Second concrete mix trial will be made as a replacement of natural sand with waste foundry sand by weight (10%,20%,30%). Third mix trial will be made by taking the optimum value of WSF from trial second and silica fume is added with replacement of cement by weight (5%, 10%, 15%). Fourth trial mix will be made as a replacement of natural sand with waste foundry by weight (taking optimum from trial second) and glass powder is added with a replacement of cement by weight of cement (5%,10%, &15%). Compression, splittensile strength & flexural strength test will be carried out on 7th, 14th, 28th, & 56th day. After evaluating the test result of each trial mix, finally we will compare the final result of each trial mix and see how concrete behaves in each concrete mix trials.
|
2022-01-27T01:55:20.633Z
|
64,055,890 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3828/indexer.2005.24.4.11",
"MAG": "2499804322",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Subheadings assist the reader in navigating the webs of information presented by the text. This article, condensed from Facing the text: content and structure in book indexing, provides guidelines for the process of choosing subheadings, emphasizing their function of breaking down the information in the main heading.
|
2022-07-30T16:41:40.634Z
|
79,105,125 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3757/JSER.43.236",
"MAG": "2519254899",
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},
"license": null,
"status": null,
"url": null
}
|
The head-shaking test provokes effectively a latent spontaneous vestibular nystagmus (head-shaking nystagmus). The diagnostic significance of head-shaking nystagmus for the site of lesion was studied on 191 patients who visited our otologic clinic from 1980 to 1982 with complaints of dizziness.1. In 78.7% of the patients of unilateral lesion, the nystagmus was directed contralateral to the site of lesion, and in 21.3%, ipsilateral.2. In 79.3% of the patients of unilateral hearing loss, the nystagmus was directed contralateral to the site of hearing loss, and in 20.7%, ipsilateral.3. In 96.7% of the patients with caloric abnormality, the nystagmus was directed contralateral to the site of canal paresis (CP), and in 3.3%, ipsilateral.In 4 patients with directional preponderance (DP), the nystagmus had the same direction as DP.4. The head-shaking nystagmus, which is directed contralateral to the site of lesion, the site of hearing loss, or the site of CP, is considered as the deficiency nystagmus, while the nystagmus, which is directed ipsilateral, is considered as the recovery nystagmus. The both types of nystagmus can be distinguished from their styles of beating.5. The biphasic nystagmus was observed in 9 patients with peripheral lesions. The 1st phase was considered to be the deficiency nystagmus, and 2nd phase, recovery nystagmus.
|
2022-08-21T03:05:38.954Z
|
51,612,321 |
{
"externalids": {
"ACL": null,
"ArXiv": "1706.03373",
"DOI": "10.1109/TBME.2018.2812602",
"MAG": "2962778826",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A multiple instance dictionary learning approach, dictionary learning using functions of multiple instances (DL-FUMI), is used to perform beat-to-beat heart rate estimation and to characterize heartbeat signatures from ballistocardiogram (BCG) signals collected with a hydraulic bed sensor. DL-FUMI estimates a “heartbeat concept” that represents an individual's personal ballistocardiogram heartbeat pattern. DL-FUMI formulates heartbeat detection and heartbeat characterization as a multiple instance learning problem to address the uncertainty inherent in aligning BCG signals with ground truth during training. Experimental results show that the estimated heartbeat concept obtained by DL-FUMI is an effective heartbeat prototype and achieves superior performance over comparison algorithms.
|
2022-09-15T21:49:35.009Z
|
9,503,545 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3382/ps.2007-00291",
"MAG": "2163462667",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "HYBRID",
"url": "https://doi.org/10.3382/ps.2007-00291"
}
|
This research was conducted to determine the effects of feeding different P levels with and without phytase supplementation on broiler growth performance, bone-breaking strength (BBS), and litter P concentration. An experiment with 4 trials was conducted with 7,840 Ross x Ross straight-run broilers. For each trial, 1,960 broilers were allotted on d 0 to treatments, with 7 replications each and with 70 broilers per replication. The broilers were fed a 4-period feeding program consisting of starter (0 to 14 d), grower (14 to 32 d), finisher (32 to 41 d), and withdrawal (41 to 50 d) periods. For each trial, the same pen was used continuously for each treatment-replication combination, and the litter was not removed between trials. Broilers were fed a control diet [0.43, 0.40, 0.36, or 0.32% nonphytate P (nPP)] in the starter, grower, finisher, and withdrawal periods, respectively, a low Ca and P (LCaP) diet with a 0.05% reduction in nPP in each period, and these 2 diets supplemented with phytase at 600 phytase units/kg (nPP and Ca were reduced by 0.094% in diets with phytase). Diet did not affect (P > 0.10) broiler performance in the starter or withdrawal periods. Generally, both phytase addition and the LCaP diet decreased some aspects of growth performance during the grower and finisher periods. There was no main effect of phytase on BBS, but BBS was decreased in the broilers fed the LCaP diet with phytase addition (nPP x phytase, P < 0.01) in the grower period, and BBS was decreased in the finisher (P < 0.02) and withdrawal (P < 0.01) periods for broilers fed the LCaP diet. Total P, soluble P (SP), and reactive soluble P (RSP) were decreased (P < 0.04) in the litter of broilers fed the LCaP diets. Total P, SP, and RSP were decreased (P < 0.01) in the litter of broilers fed phytase. These data indicate that phytase supplementation at 600 phytase units/kg reduces growth in some periods, has no effect on BBS, and reduces total P, SP, and RSP in the litter.
|
2022-12-19T23:02:23.772Z
|
239,017,988 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.3233/bmr-210051",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
BACKGROUND
To restore core stability, abdominal drawing-in maneuver (ADIM), abdominal bracing (AB), and dynamic neuromuscular stabilization (DNS) have been employed but outcome measures varied and one intervention was not superior over another.
OBJECTIVE
The purpose of this study was to compare the differential effects of ADIM, AB, and DNS on diaphragm movement, abdominal muscle thickness difference, and external abdominal oblique (EO) electromyography (EMG) amplitude.
METHODS
Forty-one participants with core instability participated in this study. The subjects performed ADIM, AB, and DNS in random order. A Simi Aktisys and Pressure Biofeedback Unit (PBU) were utilized to measure core stability, an ultrasound was utilized to measure diaphragm movement and measure abdominal muscles thickness and EMG was utilized to measure EO amplitude. Analysis of variance (ANOVA) was conducted at P< 0.05.
RESULTS
Diaphragm descending movement and transverse abdominis (TrA) and internal abdominal oblique (IO) thickness differences were significantly increased in DNS compared to ADIM and AB (P< 0.05). EO amplitude was significantly increased in AB compared to ADIM, and DNS.
CONCLUSIONS
DNS was the best technique to provide balanced co-activation of the diaphragm and TrA with relatively less contraction of EO and subsequently producing motor control for efficient core stabilization.
|
2022-02-07T20:25:10.354Z
|
239,060,099 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.20473/jsd.v16i2.2021.140-150",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBYNCSA",
"status": "HYBRID",
"url": "https://e-journal.unair.ac.id/DIALEKTIKA/article/download/26512/15440"
}
|
Contraception is an effort used to prevent pregnancy in women of childbearing age. Presently, contraception is not only used for adult women or those who have had a partner, but also for female adolescents. This study aimed to understand the practice of using contraceptives among female adolescents in rural areas. The theory used as an analytical tool was the theory of social construction by Peter L Berger and Thomas Luckmann. This study used a qualitative method. The research subjects in this study were women who used contraceptives as an adolescent. This study showed that the use of contraceptives or family planning by female adolescents in the Kabuh District is a common practice. Female adolescents interpreted family planning practices as prevention of pregnancy. The most commonly used contraceptives are the contraceptive injection and the birth control pill. Adolescents obtained preference for contraceptives from their parents and family. Meanwhile, family planning services were only provided through a midwife using the One-Stop Service method. Cultural values and customs that are deeply rooted in the Manduro community make the practice of pre-marital family planning perpetuated, even though it contradicts information in general and religion. This study concluded that the practice of pre-marital family planning is believed to be the best solution for female adolescents who are engaged but still want to seek new experiences.
|
2022-02-07T07:59:31.009Z
|
151,452,138 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.18276/PZFM.2015.38-12",
"MAG": "2518802790",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Zachowania konsumentow podlegają ustawicznym transpozycjom. Z jednej strony są one modelowane przez ciągly rozwoj technologii teleinformatycznych i dynamiczne zmiany obserwowane na rynku. Z drugiej jednak strony zachowania stają sie czynnikiem sprawczym i przyczyniają sie do kolejnych przeobrazen. Niniejszy artykul ma na celu przedstawienie trendow konsumenckich osob niepelnosprawnych ruchowo, ktore pojawiają sie lub nasilają we wspolczesnym spoleczenstwie konsumpcyjnym w kontekście tendencji do digitalizacji stosunkow spolecznych. Pierwsza tura przeprowadzonych badan ukazala, ze osoby niepelnosprawne coraz cześciej wykazują sklonności do zachowan prosumenckich przez wyrazanie swoich opinii i oczekiwan za pośrednictwem portali spolecznościowych, forow internetowych i stron www producentow. Grupa konsumentow niepelnosprawnych jako podmiot prowadzonych rozwazan zostala wybrana nie bez przyczyny – jest to grupa bardzo liczna, zarowno w Polsce, jak i w na świecie oraz nie jest ona wyczerpująco opisana w literaturze przedmiotu.
|
2022-02-09T03:22:17.518Z
|
13,881,258 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICTC.2015.7354653",
"MAG": "2201616907",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this work, the performance of the sub-optimum improved parametric linear combination pulse (IPLCP) in orthogonal frequency division multiplexing (OFDM) based systems is evaluated. An OFDM-based system, in the presence of carrier phase noise and carrier frequency offset, is evaluated in terms of BER. The IPLCP is characterized by having three additional design parameters, adding extra degrees of freedom to reduce the BER in OFDM-based systems. Two of the constants were fixed, whereas the other one was optimized via numerical simulations for BER reduction. The sub-optimum IPLCP outperforms the other evaluated pulses in terms of BER.
|
2022-02-13T03:11:16.070Z
|
211,162,144 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/00036846.2020.1739224",
"MAG": "3124495571",
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},
"license": "CCBYNCND",
"status": "GREEN",
"url": "https://e-archivo.uc3m.es/bitstream/10016/29633/1/we2001.pdf"
}
|
ABSTRACT The main objective of this article is to analyse the different sources of asymmetric price transmissions in the fuel market for France, Germany and Spain. During the last decades, the EU has carried out several common energy policies to achieve more efficient and competitive markets. However, given the specific characteristics of each country, the question we want to address is if fuel prices across EU members behave differently in response to different market structures. Oil operators have been targeted by competition authorities for conducting non-competitive practices. To figure out whether the common complaint that gasoline prices adjust differently to positive or negative input price changes, dynamic asymmetric models for the mean and variance are developed for each country. Several asymmetric specifications for the mean and variance are considered. The best specification combines double threshold error correction models (DT-ECM) for the mean with asymmetric EGARCH plus an asymmetric dummy variable for the conditional variance. We show that French gasoline prices behave more competitively, adjusting quicker to the long-run equilibrium and with more price volatility. This outcome is consistent with the strong presence of hypermarkets following low-cost pricing strategies in France.
|
2022-12-18T03:53:49.536Z
|
220,836,531 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/000271623216100101",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
THIS volume on &dquo;Modern Insurance Developments&dquo; is a successor to the volumes on &dquo; Modern Insurance Tendencies &dquo; published by the American Academy in March 1987, and &dquo;Modern Insurance Problems&dquo; published by the American Academy in March 1917. Like its predecessors, this volume aims to record the outstanding changes and tendencies of the past five years in the leading types of insurance. Certain tendencies, owing to their noteworthy development and outstanding importance, are given special emphasis in a number of articles. Thus, three articles are devoted to the investment nature of life insurance, a factor greatly stressed during the present industrial depression, and five articles
|
2022-01-27T05:33:16.293Z
|
194,503,220 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.19136/MHR.A1N1.1339",
"MAG": "2430812086",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Algunos pacientes consideran el uso de la medicina alternativa y complementaria (MAC) como una opcion de tratamiento. Hasta el momento no se han reportado estudios que describan el uso de MAC en pacientes con cancer en el estado de Tabasco. Este estudio tiene el objetivo de identificar el uso de medicina alternativa y complementaria en pacientes con cancer de mama que acuden a un Hospital regional de alta especialidad. Metodo: Estudio descriptivo transversal. La muestra estuvo conformada por 105 pacientes con diagnostico de cancer de mama, que acuden a la consulta externa de oncologia de un Hospital de Alta Especialidad en Tabasco, Mexico. La recoleccion de datos se hizo a traves de un cuestionario validado, de uso de MAC (Ezeome y Anarado, 2007) Resultados: El uso de MAC predomino en el 94% de la poblacion, siendo los mas comunes los productos biologicos (42%), donde se considera las plantas medicinales. Seguido de una dieta especial o regimen alimentario (33%). El 81.3% describio que usaban la MAC al mismo tiempo que el tratamiento convencional para que ambos actuaran mejor, segun su percepcion. El 68.8% esperaba que, con el uso de la MAC, se curara o tratara directamente el cancer. Sin embargo, el 45% de los pacientes describio que solo percibio una mejora de su bienestar fisico como uno de los beneficios obtenidos con el uso de estas. Conclusion: El uso MAC es comun en los pacientes con cancer de mama. Es importante que el clinico pregunte acerca del uso de MAC, para llevar mejor control del paciente. Abstract Some patients consider necessary the use of alternative and complementary medicine (ACM) as a treatment option for their illnesses. There are not prior reports describing the use of ASM in patients with cancer in the estate of Tabasco. The objective of this study was to identify the use of alternative and supplementary medicine in patients with breast cancer that attend a regional specialty hospital. Methods: Cross-sectional descriptive study. The sample consisted of 105 patients with breast cancer diagnosis who attended oncology outpatient consultation sessions in a specialty hospital in Tabasco, Mexico. Data was collected using a validated ASM use questionnaire (Ezeome & Anarado, 2007). Results: Use of ASM was reported in 94% of the sample, being biological products, which include medicinal plants, the most used (42%). Special diets were the second most reported option (33%). 81% of the sample reported using ASM along with conventional treatment to improve efficacy of both, according to their perspective. 66.8% of the participants expected that with the use of ASM they would heal or directly treat cancer. Nevertheless, 45% of the sample described only being benefited with physical wellbeing as a result. Conclusion: The use of ASM is frequent in patients with breast cancer. It is important that clinicians ask patients about their use of ASM for a better patient control.
|
2022-02-08T08:14:54.785Z
|
38,088,017 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1080/00325481.1979.11715054",
"MAG": "2412214709",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Heparin and warfarin are antithrombotic agents effective against venous thrombosis as well as pulmonic and systemic emboli. They can exert a favorable effect on mortality and morbidity in a diverse group of illnesses associated with thrombosis. Proper use of these agents will increase their efficacy and diminish the risk of serious hemorrhage.
|
2022-02-12T06:42:39.751Z
|
56,718,122 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/PESGM.2018.8586603",
"MAG": "2906071679",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Due to the increasing replacement of conventional generators with renewable energy sources (RESs), the number of power system stabilizers (PSSs) installed in power systems may decrease in the future, resulting in a reduced capability to control power oscillations. This paper presents a multi-modal power oscillation damping (POD) controller that can improve the damping of multiple low-frequency oscillations. The controller is designed and installed in a proposed future High Voltage Direct Current (HVDC) transmission system modelled in a reduced order dynamic equivalent model of Great Britain (GB) system. The design process has been analyzed concerning variable time delays associated with communication systems used with wide-area measurements. MATLAB and DIgSILENT are used in the design and simulation of the controller. The multi-modal controller is shown to provide a significant improvement in damping of multiple modes of oscillations.
|
2022-02-11T19:10:27.751Z
|
21,755,727 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1089/10445490150504684",
"MAG": "2021638166",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Members of the steroid-thyroid-retinoid receptor superfamily regulate a spectrum of cellular functions, including metabolism and growth and differentiation. We sought to isolate novel members of this family by using degenerate oligonucleotide primers directed to sequences encoding the AF-2 domain of these molecules in a PCR-based approach. The AF-2 domain serves a critical function in recruiting coregulatory molecules and in transcriptional activation. We report the cloning and initial characterization of a novel gene, WDR10, which encodes a 140-kD protein that is highly expressed in pituitary and testis. This protein, WDR10p, contains an AF-2 domain as well as seven N-terminal WD repeats and is highly conserved through evolution. Chromosomal localization studies placed WDR10 at 3q21, near a locus for the Moebius syndrome, Hailey-Hailey disease, and rhodopsin, which is involved in several forms of retinitis pigmentosa. The expression pattern of WDR10 and its chromosomal location makes this novel gene a candidate gene for the hypogonadism associated with some forms of retinitis pigmentosa and the Moebius syndrome.
|
2022-10-23T16:14:14.323Z
|
3,388,908 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/cas.13455",
"MAG": "2769583779",
"PubMedCentral": "5797825"
},
"license": "CCBYNC",
"status": "HYBRID",
"url": "https://doi.org/10.1111/cas.13455"
}
|
DNA replication is one of the fundamental biological processes in which dysregulation can cause genome instability. This instability is one of the hallmarks of cancer and confers genetic diversity during tumorigenesis. Numerous experimental and clinical studies have indicated that most tumors have experienced and overcome the stresses caused by the perturbation of DNA replication, which is also referred to as DNA replication stress (DRS). When we consider therapeutic approaches for tumors, it is important to exploit the differences in DRS between tumor and normal cells. In this review, we introduce the current understanding of DRS in tumors and discuss the underlying mechanism of cancer therapy from the aspect of DRS.
|
2022-12-18T18:50:19.323Z
|
120,514,254 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CLEOPR.1995.521383",
"MAG": "1886762186",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
pabilities of key devices and components suitable for use in photonic packetswitched networks are reviewed. Photonic approaches to packet switching have been motivated by the need for high-capacity optically transparent self-routing swit~hes:~ and add/ drop switches for ring and bus net~ o r k s . 6 . ~ The switching and/or routing fabric in recent demonstrations of photonic packet switching has generally been optical. However, electronic components and circuits remain attractive alternatives to photonic devices in functions such as address processing, switch control, and buffer control. Key issues affecting the operation and implementation of photonic packet switches include contention resolution, buffering, and packet synchronisation. The difficulty in implementing fully-functional photonic equivalents to the electronic shift register makes clocked optical buffering and synchronisation difficult. Possible approaches to the buffering problem include optical buffering usin fibre delay lines either in re~irculating,2.~' serial: or parallel'0,'' configurations. An overview of approaches to optical buffering will be given, and buffer memory capabilities will be reviewed.
|
2022-02-09T22:17:18.661Z
|
31,800,955 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2222/jsv.23.125",
"MAG": "2475332603",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://www.jstage.jst.go.jp/article/jsv1958/23/2/23_2_125/_pdf"
}
|
The authors' virus watch program on an infant asylum in Toyama City revealed that adenoirus type 1 (Adv. 1) was prevailing in the population over a period from May, 1966, to June, 1968. Each individual was examined quantitatively for antibodies against Adv. 1 (NT and HI) in relation to virus isolation from feces. The following results were obtained.1. A systematic pursuit was required for the study of Adv. 1 infection on virus isolation from feces and antibody contents in serum in each individual. In many cases, Adv. 1 was excreted intermittently. No significant antibody reponse was observed over a period from 2 to 4 months after the first virus isolation.2. No antibodies in serum seemed to affect Adv. 1 in feces. The infectivity of Adv. 1 in fecal specimens to HeLa S3 cell culture was low, but remained unchanged even after antibodies against Adv. 1 were detectable in serum.3. HEK cells exhibited a higher susceptibility to Adv. 1 than HEL and HeLa S3 cells, which became as susceptible to Adv. 1 as HEK cells after 2-3 blind passages. Hep-2 cells were less susceptible to the same virus than any of the three types of cells.4. No significant clinical signs were manifested even by children excreting Adv. 1 intermittently for a long period of time.
|
2022-05-29T14:23:28.957Z
|
72,970,267 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.6084/M9.FIGSHARE.892326.V1",
"MAG": "2152766922",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Health care delivery systems throughout the world have undergone significant changes in the past few decades. These changes have been driven—at least partly—by the recent advances in medical science and the emergence and subsequent adoption of new diagnostic and therapeutic technologies. In addition, growing populations, population aging, changes in disease prevalence have led to increased health service utilization (Walburg et al., 2006; Blumenthal, 2009; Walshe & Smith, 2011). The several changes in the health care environment were accompanied by changes in models of health care delivery and organization and in patient utilization patterns, all of which led to substantial increases in health care costs. All these factors call for more effective and more efficient health care management practices (Fisher et al., 2009; Van Herck et al., 2010; Walshe & Smith, 2011). In addition, there are rising demands—further backed by governments, non-governmental organizations, and the media— for greater accountability and better health care service. At the same time, there has been a fall in the implicit trust patients have always had in medical professionals, which can be attributed, at least in part, to the high-profile scandals and failures in a number of health care systems around the world. Also, the increased media coverage and the rise of the Internet as a new mass medium have certainly accelerated the change. Patients, in many parts of the world, call for a greater role in their own health care, greater choice, and more involvement in decisions relating to their treatment. There is now a growing global trend toward reduced professional power and autonomy and a rise in managerialism and clinical governance (Marshall & Campbell, 2002; Buttell et al., 2008). These manifestations are considered to be part of a bigger picture comprising economic and social changes and are often linked to the wider movement and culture of consumerism. A number of forces have contributed to the rise of consumerism in health care including the demographic shifts and changes in populations, the increasing concerns about patient safety, and the relatively higher availability of medical knowledge to the public (Walburg et al., 2006; Ovretveit, 2009; Calnan, 2010; Walshe & Smith, 2011; Ewert & Evers, 2012). There are now raised expectations of greater transparency and more information about health care services, improved health
|
2022-06-04T05:44:43.069Z
|
80,121,625 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4314/TJPR.V16I8.22",
"MAG": "2753331896",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Purpose: To systemically explore the pharmacological mechanisms of traditional Chinese medicine, Yinlai Decoction (YD), used in the clinical management of pediatric diseases such as pneumonia and recurrent respiratory tract infections. Methods: An ingredient-target-disease database of YD was constructed using Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP). First, the molecular targets related to lung and stomach diseases were searched and screened to avoid duplication. Second, the associations between these molecular targets were evaluated via Search Tool for the Retrieval of Interacting Genes/Proteins (STRING) and Gene Ontology (GO) and Pathway enrichment analysis in STRING. Results: A total of 627 chemical ingredients and 654 protein targets in YD were obtained. After further screening, 38 molecular targets linked to respiratory diseases, inflammatory responses and various infections were identified. Finally, 576 GO terms and 75 KEGG pathway terms were obtained by analyzing gene functional annotation clusters and abundance value of these targets. Most of these terms were closely related to the inflammatory response. Conclusion: Based on these in silico findings, the use of YD for treating respiratory diseases, inflammation and various infections, most probably via the suppression of inflammation, has been established. The approach adopted in this study can serve as a model methodology to develop an innovative TCM candidate drug at a network pharmacology level. Keywords: Yinlai Decoction, Network (System) pharmacology, Inflammation, Interacting genes/proteins, Gene ocntology, Pathway enrichment analysis
|
2022-02-11T03:21:46.863Z
|
14,000,829 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3389/fncir.2014.00066",
"MAG": "2091179466",
"PubMedCentral": "4072101"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.frontiersin.org/articles/10.3389/fncir.2014.00066/pdf"
}
|
“Dye-coupling”, whole-mount immunohistochemistry for gap junction channel protein connexin 35 (Cx35), and freeze-fracture replica immunogold labeling (FRIL) reveal an abundance of electrical synapses/gap junctions at glutamatergic mixed synapses in the 14th spinal segment that innervates the adult male gonopodium of Western Mosquitofish, Gambusia affinis (Mosquitofish). To study gap junctions’ role in fast motor behavior, we used a minimally-invasive neural-tract-tracing technique to introduce gap junction-permeant or -impermeant dyes into deep muscles controlling the gonopodium of the adult male Mosquitofish, a teleost fish that rapidly transfers (complete in <20 mS) spermatozeugmata into the female reproductive tract. Dye-coupling in the 14th spinal segment controlling the gonopodium reveals coupling between motor neurons and a commissural primary ascending interneuron (CoPA IN) and shows that the 14th segment has an extensive and elaborate dendritic arbor and more gap junctions than do other segments. Whole-mount immunohistochemistry for Cx35 results confirm dye-coupling and show it occurs via gap junctions. Finally, FRIL shows that gap junctions are at mixed synapses and reveals that >50 of the 62 gap junctions at mixed synapses are in the 14th spinal segment. Our results support and extend studies showing gap junctions at mixed synapses in spinal cord segments involved in control of genital reflexes in rodents, and they suggest a link between mixed synapses and fast motor behavior. The findings provide a basis for studies of specific roles of spinal neurons in the generation/regulation of sex-specific behavior and for studies of gap junctions’ role in regulating fast motor behavior. Finally, the CoPA IN provides a novel candidate neuron for future studies of gap junctions and neural control of fast motor behaviors.
|
2022-09-07T03:07:34.826Z
|
36,064,750 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1126/science.141.3581.649",
"MAG": "2090760430",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Polyploid human cells in culture often have paired sex chromatin masses. They are neither chance juxtapositions of randomly distributed X chromosomes nor manifestations of a propensity for pairing. The pairs are characteristic of the first polyploid interphase. They are thought to reflect the persistent differentiation of X chromosomes, as proposed in the Lyon hypothesis.
|
2022-09-09T03:50:45.307Z
|
98,445,560 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1039/C39790000668",
"MAG": "2065330653",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Chiral hydrazones, obtained by the condensation of (–)-N-aminoephedrine with aryl aldehydes, reacted with Grignard reagents to give chiral hydrazines in almost 100% diastereomeric excess, which were hydrogenolysed to give (R)-α-phenylalkylamines and ephedrine hydrochloride in extremely high enantiomeric excess.
|
2022-09-14T09:28:02.305Z
|
142,550,404 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3917/EG.412.0128",
"MAG": "1532982674",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A la croisee entre modeles spatiaux, scenarios spatialises et concertation sur l’avenir d’un territoire, la geoprospective donne une importance variable a chacun de ces trois volets. L’article analyse comment la modelisation d’accompagnement fait de la geoprospective et sous quelle forme particuliere. La reflexion porte d’abord sur la demarche de modelisation : explication du modele du domaine, co-construction du modele conceptuel, definition de scenarios et leur simulation exploratoire. Ensuite sont abordees les questions sur le niveau de realisme des modeles spatialises, la prise en compte de differentes echelles d’espace et de temps, et la place du modelisateur et des modeles qu’il propose comme objets intermediaires entre les acteurs et leur territoire.
|
2022-10-21T00:51:36.942Z
|
252,681,934 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/tox.23669",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Different subtypes of breast cancer express positively G protein‐coupled estrogen receptor 1 (GPER1). Our previous studies found that tetrachlorobisphenol A (TCBPA) and bisphenol AF (BPAF) significantly promoted SK‐BR‐3 cell proliferation by activating GPER1‐regulated signals. The present study further investigated the effects of TCBPA and BPAF on the migration of SK‐BR‐3 cells and examined the role of phosphatidylinositol 3‐kinase‐protein kinase B (PI3K/Akt) and its downstream signal targets in this process. We found that low‐concentration BPAF and TCBPA markedly accelerated the migration of SK‐BR‐3 cells and elevated the mRNA levels of target genes associated with PI3K/Akt and mitogen‐activated protein kinase (MAPK) signals. TCBPA‐ and BPAF‐induced upregulation of target genes was significantly reduced by GPER1 inhibitor G15, the PI3K/Akt inhibitor wortmannin (WM), and the epidermal growth factor receptor (EGFR) inhibitor ZD1839 (ZD). G15 and WM also decreased cell migration induced by TCBPA and BPAF. The findings revealed that TCBPA and BPAF promoted SK‐BR‐3 cell migration ability by activating PI3K/Akt signaling pathway via GPER1‐EGFR.
|
2022-12-18T07:39:03.041Z
|
110,748,255 |
{
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"DOI": "10.4314/AS.V1I1.1465",
"MAG": "647231400",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Meaningful agricultural development in any society largely hinges on the Extension System in place. The developed economics such as the United States of America have evolved, over time, highly workable extension systems. In spite of this, extension is seen as a dynamic process which requires regular modifications in order to make it relevant in a constantly changing technological world. In Nigeria, much of our extension activities are borrowed from alien technologies, and there are lots of deficiencies. There is need to get Extension going in order to attempt to catch up in the next century.
|
2022-02-10T04:53:15.928Z
|
73,040,832 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1590/S1135-57272005000200002",
"MAG": "2155951956",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
:«El mundo ha cambiado, debemos cam-biar nosotros. Ante todo dejando de fingirque todo es como antes, que podemos seguirviviendo cobardemente una vida normal.Con lo que estAE sucediendo en el mundonuestra vida no puede, no debe ser normal.Deberiamos avergonzarnos de esta normali-dad».Todo en nosotros deberia sublevarse antela sugerencia de que vivimos en una situa-cion «normal». La gente construye sus casassobre la falda del volcAEn, y a partir delsegundo aaeo lo han olvidado ya... Es muyhumano, demasiado humano, pero al mismotiempo resulta inaceptable.2Pocas semanas despuOs de la muerte deTerziani teniamos el barril de petroleo a mAEsde cuarenta y cinco dolares, y todas las sire-nas de alarma aullaban al unisono en la ciu-dad alegre y confiada... iInflacion, desem-pleo, estancamiento, crisis! El dedo acusa-dor seaealaba hacia las torpezas mAEs o menoscriminales Œla criminal guerra de Irak, elacoso torpe de Putin contra la petroleraYukosŒ, pero sobre todo hacia las «causasestructurales»: iel consumo en China y laIndia sube a medida que sustituyen algunasde sus bicicletas por automoviles! Es decir, amedida que hacen precisamente lo que nos-otros Œlos especialistas en «desarrollo»Œ leshemos dicho que hay que hacer.Va acercAEndose el momento de decidir.No hay en este planeta espacio ambiental nibienes ecologicos suficientes para que algu-nos cientos de millones de consumidoresmAEs se incorporen a nuestro «modelo dedesarrollo»: Oste es excluyente por defini-cion (aunque nos hemos venido negando conobstinacion a reconocer esta verdad palma-ria). Ahora, una de dos: o cambiar estemodelo Œy entonces hace falta trabajar, pro-ducir y consumir de otra maneraS, o des-plegar y perfeccionar las estructuras depoder fascistas que in nuceya existen, demanera que la raza de los seaeores dominesobre las razas de los esclavos dentro de unmundo congelado en desigualdades atroces.Tertium non datur .
|
2022-02-11T09:23:30.207Z
|
125,849,864 |
{
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"DOI": "10.12973/EU-JER.5.3.125",
"MAG": "2547699410",
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"license": null,
"status": null,
"url": null
}
|
The main purpose of this study is to determine the amount of time-dependent learning of "solving problems that require establishing of single variable equations of the first order" of the seventh grade students. The study, adopting the screening model, consisted of a total of 84 students, including 42 female and 42 male students at the seventh grade. Data was collected using an assessment tool consisting of 10 open-ended questions. The findings show that the learning group of 84 students were behind the value closest to the full learning level by a score of 0.013. While the female students reached the lower limit of 0.987 specified for the full learning level in a period of 3.2 course hours, the male students reached this limit in 4.0 course hours. The learning amount of 0.999, which is the closest value to the full learning level, was reached by the learning group in a period of 9.7 course hours, the female students in 8.5 course hours, and the male students in 11.3 course hours. In addition to this, the data obtained showed that learning difficulties among to the learning groups decreased as the space below the curve of time and learning amount decreased. As a result of the study, it was recommended that it is possible to determine the closest course periods for the full learning level for each of the gains found in all levels of education and all teaching programmes, which define certain learning outcomes within a certain time.
|
2022-04-03T17:31:36.341Z
|
20,731,197 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1103/PHYSREVB.54.602",
"MAG": "1659547245",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The quasiparticle spectral function is calculated for the 2D Hubbard model of Bi2212 with n similar to 0.9. For momenta k > k(F) we obtain dips and satellite peaks at energies omega < 0 which are caused by strong scattering of quasiparticles on antiferromagnetic spin fluctuations. These structures, which may be observable, become very pronounced below T-c, even for momenta k lying along the node of the d(x2-y2) wave gap. For k along the antinode of the gap we obtain below T-c a shift of the quasiparticle peak and a dip in qualitative agreement with ARPES measurements on Bi2212.
|
2022-09-24T13:30:24.527Z
|
6,098,586 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4085/1062-6050-43.4.359",
"MAG": "1998028201",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://meridian.allenpress.com/jat/article-pdf/43/4/359/1453419/1062-6050-43_4_359.pdf"
}
|
CONTEXT
The deceleration phase of the throwing motion creates large distraction forces at the shoulder, which may result in posterior shoulder tightness and ensuing alterations in shoulder range of motion (ROM) and may result in an increased risk of shoulder injury. Researchers have hypothesized that various stretching options increase this motion, but few data on the effectiveness of treating such tightness are available.
OBJECTIVE
To evaluate the acute effects of "sleeper stretches" on shoulder ROM.
DESIGN
Descriptive with repeated measures.
SETTING
Biomechanics laboratory and 2 separate collegiate athletic training facilities.
PATIENTS OR OTHER PARTICIPANTS
Thirty-three National Collegiate Athletic Association Division I baseball players (15 pitchers, 18 position players; age = 19.8 +/- 1.3 years, height = 184.7 +/- 6.4 cm, mass = 84.8 +/- 7.7 kg) and 33 physically active male college students (age = 20.1 +/- 0.6 years, height = 179.6 +/- 6.6 cm, mass = 83.4 +/- 11.3 kg) who reported no recent participation (within 5 years) in overhead athletic activities.
INTERVENTION(S)
Range-of-motion measurements of the dominant shoulder were assessed before and after completion of 3 sets of 30-second passive sleeper stretches among the baseball players. The ROM measurements in the nonthrower group were taken using identical methods as those in the baseball group, but this group did not perform any stretch or movement between measurements.
MAIN OUTCOME MEASURE(S)
Internal and external glenohumeral rotation ROM and posterior shoulder motion (glenohumeral horizontal adduction).
RESULTS
In the baseball group, posterior shoulder tightness, internal rotation ROM, and external rotation ROM were -3.5 degrees +/- 7.7 degrees , 43.8 degrees +/- 9.5 degrees , and 118.6 degrees +/- 10.9 degrees , respectively, before the stretches and were -1.2 degrees +/- 8.8 degrees , 46.9 degrees +/- 9.8 degrees , and 119.2 degrees +/- 11.0 degrees , respectively, after the stretches. These data revealed increases in posterior shoulder motion (P = .01, effect size = 0.30) and in internal shoulder rotation (P = .003, effect size = 0.32) after application of the stretches. No other differences were observed in the baseball group, and no differences were noted in the nonthrower group.
CONCLUSIONS
Based on our results, the sleeper stretches produced a statistically significant acute increase in posterior shoulder flexibility. However, this change in motion may not be clinically significant.
|
2022-11-17T01:39:21.004Z
|
27,375,881 |
{
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"DOI": "10.1104/pp.15.00049",
"MAG": "2017713186",
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},
"license": null,
"status": "BRONZE",
"url": "http://www.plantphysiol.org/content/plantphysiol/167/4/1643.full.pdf"
}
|
An unusual multidomain glutaredoxin and its protein partner affect plant development and flowering time in relation to photoperiod in Arabidopsis. Glutaredoxins (GRXs) catalyze the reduction of protein disulfide bonds using glutathione as a reductant. Certain GRXs are able to transfer iron-sulfur clusters to other proteins. To investigate the function of Arabidopsis (Arabidopsis thaliana) GRXS17, we applied a strategy combining biochemical, genetic, and physiological approaches. GRXS17 was localized in the nucleus and cytosol, and its expression was elevated in the shoot meristems and reproductive tissues. Recombinant GRXS17 bound Fe2S2 clusters, a property likely contributing to its ability to complement the defects of a Baker’s yeast (Saccharomyces cerevisiae) strain lacking the mitochondrial GRX5. However, a grxs17 knockout Arabidopsis mutant exhibited only a minor decrease in the activities of iron-sulfur enzymes, suggesting that its primary function is as a disulfide oxidoreductase. The grxS17 plants were sensitive to high temperatures and long-day photoperiods, resulting in elongated leaves, compromised shoot apical meristem, and delayed bolting. Both environmental conditions applied simultaneously led to a growth arrest. Using affinity chromatography and split-Yellow Fluorescent Protein methods, a nuclear transcriptional regulator, the Nuclear Factor Y Subunit C11/Negative Cofactor 2α (NF-YC11/NC2α), was identified as a GRXS17 interacting partner. A mutant deficient in NF-YC11/NC2α exhibited similar phenotypes to grxs17 in response to photoperiod. Therefore, we propose that GRXS17 interacts with NF-YC11/NC2α to relay a redox signal generated by the photoperiod to maintain meristem function.
|
2022-12-21T03:08:33.775Z
|
255,206,750 |
{
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"DOI": "10.22146/jsds.5234",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBYSA",
"status": "GOLD",
"url": "https://jurnal.ugm.ac.id/v3/JSDS/article/download/5234/2202"
}
|
Abstrak
Keberadaan komunitas pengungsi seringkali dipersepsikan sebagai komunitas yang tidak memiliki kemampuan untuk menjamin keberlangsungan hidupnya secara berkelanjutan. Tulisan ini berfokus pada upaya pemberdayaan komunitas pengungsi yang berada di wilayah Inggris melalui keterlibatan organisasi nonprofit yakni Sona Circle sebagai perantara antara pengungsi dan penyedia lapangan kerja. Penelitian ini menggunakan metode studi Pustaka integratif dengan penyampaian naratif. Melalui pemberdayaan komunitas diproyeksikan mampu meningkatkan taraf kesejahteraan hidup pengungsi di Inggris demi mendapatkan kesejahteraan yang berkelanjutan. Dengan menerapkan konsepsi mengenai pengungsi, integrasi finansial pengungsi, pembangunan berkelanjutan dan pemberdayaan komunitas maka peneliti mampu mengemukakan hasil penelitian yakni Sona Circle memberi pengaruh dalam mendorong integrasi finansial pada pengungsi melalui program yang bertujuan untuk menjembatani kesenjangan dengan menginisiasi pelatihan dasar sesuai pekerjaan yang diminati serta memberikan peluang magang dan pemberdayaan potensi untuk komunitas pengungsi demi tercapainya kesejahteraan hidup yang berkelanjutan.
Kata kunci: Pemberdayaan komunitas pengungsi, Integrasi Finansial, Sona Circle
Abstract
The existence of a refugee community is often perceived as a community that cannot sustainably ensure its sustainability. This study proposes an effort to empower the refugee community in the UK through the involvement of a non-profit organization, namely Sona Circle as an intermediary between refugees and job providers. This study uses an integrative literature studies method in narrative way . Through community empowerment, it is projected to be able to improve the living standards of refugees in the UK to obtain sustainable welfare. By applying the concept of refugees, financial integration of refugees, sustainable development, and community empowerment, the researcher can present the results of the study, namely Sona Circle influences encouraging financial integration of refugees through programs that aim to bridge the gap by initiating basic training according to the work they are interested in and provide opportunities internships and empowerment of potential for the refugee community to achieve sustainable welfare.
Keywords: Community Empowerment, Financial Integration, Sona Circle
|
2022-12-30T17:38:26.892Z
|
222,426,126 |
{
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"DOI": "10.1086/435969",
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"url": "http://www.journals.uchicago.edu/doi/pdfplus/10.1086/435969"
}
|
(25 Ap. 'I2.) ANDREWS, BENJAMIN R. The school of arts of Columbia University. Sci. Am. 106:326-27. (I3 Ap. '2.) AYDELOTTE, FRANK. English as training in thought. Educa. R. 43:354-77. (Ap. 'I2.) AYRES, LEONARD P. Measuring educational processes through educational results. School R. 20:300-9. (My. '12.) BLISS, HENRY E. Departmental libraries in universities and colleges. Educa. R. 43:387-409. (Ap. '12.) BOUGHTON, ALICE C. Administration of school luncheons. Psychol. Clinic 6:44-51. (Ap. '12.) BRYANT, LOUISE STEVENS. The school feeding movement. Psychol. Clinic 6:29-43. (Ap. '12.) (The) camp fire girls of America and their aims. R. of Rs. 45:577-81. (My.
|
2022-01-24T18:52:41.260Z
|
157,665,391 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S1468109916000281",
"MAG": "2521279987",
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},
"license": null,
"status": null,
"url": null
}
|
In the above paper one of the acronyms was expanded incorrectly. ‘COB’ is mentioned as ‘Coordination of Benefits’ (page 435) but the correct expansion is the following ‘Citizens’ Outlooks Barometer’.
|
2022-02-09T00:08:38.741Z
|
160,931,189 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4000/cediscor.552",
"MAG": "284211885",
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},
"license": null,
"status": "BRONZE",
"url": "https://journals.openedition.org/cediscor/pdf/552"
}
|
A partir de la notion d’heterogeneite, on interroge le meme texte oral que celui analyse par F. Sitri, en mettant cette fois en evidence des traces meta-enonciatives, essentiellement (auto-citations, mentions de noms propres faisant ou non « autorite », instances enonciatives diverses...). On voudrait montrer comment celles-ci participent de l’argumentation que construit le locuteur.
|
2022-07-08T00:48:37.957Z
|
153,982,742 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2307/3865989",
"MAG": "1981043248",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
SINCE the end of World War II, Canada has undergone a period of rapid economic development which has been accompanied by a rising inflow of private long-term capital from the United States. Over much of the period, and especially since the introduction of a fluctuating exchange rate in October 1950, there have also been important movements of short-term funds. Canadian experience with both types of foreign capital has been extensive enough to be of general interest as an illustration of the conditions which attract foreign capital, and of the impact of that capital on the domestic economy as well as on the payments position and exchange rate policy. Between 1946 and 1953 the net inflow of private capital into Canada amounted to about $1,540 million, plus over $1,200 million in reinvested profits.' Virtually the whole of these receipts originated in the United States, and the gross value of U.S. long-term holdings rose from $5,000 million in 1946 to $8,600 million in 1953. Holdings by overseas countries rose meanwhile by $500 million, to $2,600 million, entirely as a result of reinvested profits. Long-term receipts from the United States, apart from reinvested profits, consisted principally of direct investment by U.S. business firms in affiliated Canadian companies or branches. Before 1951 direct investment receipts were largely offset by net redemptions of portfolio securities; since that year, however, there have also been important net receipts from the proceeds of new issues. The wartime inflow of short-term funds came to an end in 1946, and transactions thereafter were light through 1949. Since then, short-term capital movements have been more volatile, first reinforcing and then neutralizing the longterm flow. In 1950, the expectation of an appreciation of the Canadian dollar led to an inflow of $770 million. The movement reversed itself after the middle of 1951, and in 1952 there was an outflow ($600 million), which continued, though on a much reduced scale, through 1953. The postwar inflow of long-term capital has coincided, like capital receipts in earlier years, with a period of heavy domestic investment. However, external receipts of new long-term capital were equivalent to
|
2022-07-28T06:24:45.699Z
|
95,208,644 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2116/ANALSCI.9.885",
"MAG": "2031399131",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A unique ring system of bicyclo[7.3.0]dodecadienediyne in neocarzinostatin chromophore has been recognized to be responsible for the antitumor activities of the antibiotic neocazinostatin. Nakatani et al.' became interested in the synthesis of stereo-defined acyclic dienendiyne systems which are closely related to the neocarzinostatin chromophore because the systems were expected to show comparable biological activities to that of neocarzinostatin. The optically active acetylene is an essential part of the systems, but two stereoisomers (II) were obtained by reaction of ketone (I) with lithium trimethylsilylacetylide or lithium acetylene (Fig. 1). Although the ketone was prepared from D-isoascorbic acid, usual spectroscopic methods could not distinguish the absolute configurations of the asterisked carbon atoms in the two isomers. The present X-ray analysis was carried out to determine unequivocally the absolute configuration of the isomer which is more polar. A colorless prism crystal (0.3X0.3X0.3 mm) was obtained from an acetone solution. The crystal and experimental data are given in Table 1. The intensity data were measured with graphite-monochromated Cu Ka radiation using an w-20 scan up to 201500.
|
2022-10-14T01:10:38.926Z
|
13,966,067 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4184/asj.2018.12.2.224",
"MAG": "2799949248",
"PubMedCentral": "5913012"
},
"license": "CCBYNC",
"status": "GOLD",
"url": "http://www.asianspinejournal.org/upload/pdf/asj-12-224.pdf"
}
|
Study Design A retrospective study of the ventral displacement of dorsal spinal cord (VDDSC) spectrum pathophysiology and grading. Purpose This study aimed at examining the pathophysiology of VDDSC between D3 and D7, using magnetic resonance imaging (MRI) correlation and severity grading. Overview of Literature The pathologies that lead to VDDSC were previously discussed in various articles. We attempted to group these pathological conditions under a single spectrum, and grade them according to their severity. Methods We reviewed the MRI images of the dorsal spines of 1,350 patients over a period of 4 years (February 2013–February 2017); all MRI images were analyzed by two experienced radiologists. Results Of the 1,350 patients, 28 exhibited VDDSC between D3 and D7. Additional findings included ventral transdural herniation of the spinal cord (n=10), anterior spinal cord adhesion (n=7), arachnoid web (n=6), and arachnoid cyst (n=5). Conclusions We grouped the pathologies that lead to VDDSC at the thoracic level into a single spectrum of varying severity and graded VDDSC, from mild to severe.
|
2022-10-28T00:34:15.514Z
|
33,340,763 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3233/BME-1997-7302",
"MAG": "2285148845",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The mechanical properties of a contracting smooth muscle can be changed by changing its length. A viscoelastic material model was developed to predict the length-dependent stiffness changes when a constrained muscle is allowed to shorten under a constant external force. Three-dimensional finite element simulations were carried out to estimate the stiffness changes and compared to available experimental data. A good agreement was found indicating that the viscoelastic material model developed gives a valid representation of the length dependent stiffness changes of a smooth muscle. Sensitivity analysis was carried out to determine the relative effects of material constants in the model on the length dependent stiffness.
|
2022-08-30T11:14:52.717Z
|
123,618,787 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/0264-9381/16/6/318",
"MAG": "2073641839",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The gravitomagnetic clock effect is the difference in periods of a test particle revolving in prograde and retrograde circular geodesic orbits around a rotating body. We study this effect for a cylindrically symmetric system, but our analysis also applies to orbits around the Kerr source in its plane of symmetry. The effect depends on the coordinate system, and we find the condition that it can be reduced to zero by a suitable choice of rotating axes. We apply our formulae to the van Stockum metric for a rotating dust cylinder, and to the Kerr solution. In the former there is a gravitomagnetic clock effect only in the case of low mass per unit length, and the coordinate system in which the effect vanishes is the one in which the distant stars would be at rest. In Kerr spacetime the gravitomagnetic clock effect can be made to vanish, but only by choosing a frame rotating with respect to the distant stars.
|
2022-10-25T10:51:57.726Z
|
237,857,988 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.18764/2447-6498.v7n1p1-13",
"MAG": "3180438991",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://doi.org/10.18764/2447-6498.v7n1p1-13"
}
|
O texto abre uma reflexão sobre a importância da arte, dos artistas e principalmente do cinema para conseguir digerir e viver bem nos tempos atuais os quais estamos vivendo em pânico. A arte proporciona a quem faz e a quem recebe diferentes níveis de abstração que nos fazem ampliar a percepção de uma compreensão do mundo. Nada existe até eu fazer um filme sobre o assunto, ou assistir um que me leve à reflexão. Através de uma retrospectiva da relação com o cinema em minha vida, escrevo sobre as razões que me motivaram a flertar, a seguir este caminho e a pensar sobre a vida através de três filmes meus: Amniogênese; O homem que ri e Casa Vazia. The Reflective Character of Cinema: the 7th art as a way of lifeABSTRACTThe text opens a reflection on the importance of art, artists and especially cinema to be able to digest and live well in the current times we are living in panic. Art provides those who make and those who receive different levels of abstraction that make us broaden the perception of an understanding of the world. Nothing exists until I make a movie about it, or watch one that makes me think. Through a retrospective of the relationship with cinema in my life, I write about the reasons that motivated me to flirt, to follow this path and to think about life through three of my films: Amniogenesis; The Man Who Laughs and an Empty House.Keywords: Cinema. Reflection through art. Art.
|
2022-11-18T00:52:56.842Z
|
247,470,552 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/axioms11030130",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2075-1680/11/3/130/pdf?version=1648001160"
}
|
This paper is centered around the creation of new fuzzy connectives using automorphism functions. The fuzzy connectives theory has been implemented in many problems and fields. In particular, the N-negations, t-norms, S-conorms and I-implications concepts played crucial roles in forming the theory and applications of the fuzzy sets. Thus far, there are multiple strategies for producing fuzzy connectives. The purpose of this paper is to provide a new strategy that is more flexible and fast in comparison with the rest. In order to create this method, automorphism and additive generator functions were utilized. The general formulas created with this method can provide new fuzzy connectives. The main conclusion is that new fuzzy connectives can be created faster and with more flexibility with our strategy.
|
2022-11-23T17:34:48.647Z
|
167,211,153 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5578/mb.67796",
"MAG": "2960729376",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
HBV is a DNA virus and the causative agent of hepatitis B infection. Hepatitis B is a contagious disease and is still a major health problem all over the world. When the infection become chronic, it may cause serious diseases such as fibrosis, cirrhosis and/or hepatocellular carcinoma. Interferon/pegylated interferon by intravenous route and nucleoside/nucleotide (NA) analogues such as lamivudine, adefovir, entecavir, telbivudine and tenofovir given by oral route are used in the treatment. Antivirals given by oral route are mostly preferred in the treatment. However, because of the replication strategy and biological properties of HBV, mutations that cause antiviral resistance against these drugs can occur at different rates, although they can vary from drug to drug over time. It is possible that drug resistant virus may transmit from patient to healthy individuals. Therefore, there is a possibility of infection with drug-resistant HBV before treatment. Antiviral resistance mutations are divided into four categories; i) Nucleos(t)ide analog resistance (NAr)-related mutations, ii) primary drug resistance mutations, iii) secondary/compensatory mutations, iv) putative antiviral resistance mutations and pre-treatment variations. Recent studies have focused particularly on putative mutations and pre-treatment variations. The aim of this study was to better understanding of the antiviral resistance profiles of chronic hepatitis B (CHB) patients treated and untreated with NA, and help to prevent unnecessary drug use, minimize the side effects and economic damages. A total of 124 patients who have received nucleoside analog (NA) drug treatments (n= 72) and patients without NA treatment (n= 52) were included in the study. Viral DNA was isolated from the plasma samples of the patients. A DNA fragment, which is 551 bp, was amplified and sequenced including the binding side of all nucleoside analogs containing the B, C and D domains located in the reverse transcriptase region in the HBV genome. Different types of mutations were detected in 13 (18.05%) of 72 treated patients and in 18 (34.61%) of 52 untreated patients (p< 0.05). Primary drug resistance mutations such as rtI169T, rtA181T/V, rtT184A/C/F/G/I/L/M/S, rtA194T, rtS202C/G/I, rtM204I/V/S, rtN236T, rt M250I/L/V and rtV173L were not detected in any of the patient samples. However, potential drug resistance mutations such as rtR164R, rtG165D/A, rtG172Q, rtS176N, rtF178V, rtA181G, rtS185N/G/C, rtV207M, rtQ215H/S, rtL231V, rtI233K, rtN238S, rtV253T, rtC256G/S and rtI266R/V were detected in untreated patient samples in B, C, D and D domains of reverse transcriptase region. Our results have suggested that the detection of pretreatment variations could be helpful for choosing the correct antiviral drug for the better treatment management.
|
2022-06-05T01:41:18.546Z
|
153,774,099 |
{
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"DOI": "10.17556/JEF.11714",
"MAG": "1922520329",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this research, competency level of education and training of the physical training guide books, implemented in the 2006-2007 acedemic year, have been researched in the direction evaluation of physical education teachers. 451 physical education teachers who work in elementary schools form the study group. To determine the opinions of the participants survey screening model is used. About the guidance book, in the views of physical education teachers (X=3,61), because of the surplus total of the classrooms (x=3.37) and teachers run courses according to old system without depending the guide book (x=3.15). Hence, subject headings and subheadings of the guide book should be held more understandable and simply to facilitate practibility of the guide book in physical education lessons, physical education field and facility should be made sufficient and provided the equipment, to reduce the number of crowded classes in schools necessary works are needed in conclusion of the research.
|
2022-02-09T02:09:39.616Z
|
103,211,603 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3866/PKU.WHXB20110307",
"MAG": "2783243556",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Sulfonated carbon nanotubes (CNTs)/activated carbon composite beads were obtained by suspension polymerization, carbonization, activation, and further sulfonation using the diazonium salt coupling method. Adsorption of low density lipoprotein (LDL) was explored with these composite beads. The results showed that the composite beads had good sphericity, smooth surface, developed mesopores and were sulfonated by p-aminobenzenesulfonic acid. With the increase of CNTs mass ratio, the adsorption capacity of LDL increased. When the CNTs mass fraction was 45% , the amount of LDL adsorption reached 6.564 mg·g-1 and was 3.3 times as large as that of the beads without CNTs. Therefore, the composite beads have good prospects as LDL adsorbents in hemoperfusion.
|
2022-02-10T09:23:51.201Z
|
29,104,817 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1159/000181787",
"MAG": "2089525298",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The reproducibility of measurements of nocturnal spontaneous secretion of growth hormone (GH) was assessed. The study population consisted of 15 short children with a variety of pathological conditions. Blood samples were taken every 20 min from each subject during sleep on two consecutive nights. The analysis of variance of matched series indicated a global reproducibility, but also demonstrated significant individual variabilities (with-in-subject effect) of both peak amplitude (p = 0.05) and mean concentration (p = 0.02). We did not find any link between the variation of the GH parameters and the variations of the clinical sleep score in 11 patients.
|
2022-02-12T13:43:53.380Z
|
204,331,104 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1136/vr.l5963",
"MAG": "2979770988",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
ffinlo Costain argues that the focus on ruminant methane in causing global warming is ill-informed and in fact restoration of grass-based systems can result in net zero emissions from UK agriculture by 2030.
|
2022-07-31T20:50:15.863Z
|
248,358,935 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/buildings12050532",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2075-5309/12/5/532/pdf?version=1650794438"
}
|
Maintenance is crucial for healthcare facilities in terms of both the continuity of operations and annual costs. Many maintenance issues are associated with design decisions that pave the way for added costs in later lifecycle stages. Some systems, e.g., elevators, are sources of maintenance costs; additionally, elevator outages are significant issues for multi-floor healthcare facilities. Considering the maintainability of elevators from the early design stages helps to highlight potential maintenance issues in later stages. This also assists in mitigating costs by avoiding design decisions that result in future maintenance costs. This research uses the expertise of facility managers who have experience with maintenance issues resulting from design decisions. A list of 35 elevator maintenance issues caused by design flaws is presented in this paper, based on the literature and semi-structured interviews with a representative sample of six healthcare facility management experts. Then, a questionnaire using convenience sampling was conducted with facility management professionals to evaluate and rank the maintenance issues. While 60 professionals responded, only 30 attempted the four-parameter evaluation of all listed maintenance issues. The results of the questionnaire determined elevator car jams, sudden stops, and working space conditions to be the most critical issues faced by facility managers in healthcare facilities. The output of this study can help designers of new healthcare facilities to avoid decisions that result in unwarranted maintenance issues with costly impacts.
|
2022-09-04T18:08:13.958Z
|
167,790,246 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/108056999605900103",
"MAG": "2061405069",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Management students need to learn both analytic and communication skills to be successful in the university and at work. Communicative methods used to teach English as a Second Language (ESL), such as collaborative learning, dialogue journals, peer review, and oral presentations, can be adapted readily to teaching analytical and communication skills to native and nonnative speakers of English. ESL strategies work well to enable learners to analyze readings and form and communicate well-developed opinions in the context of case studies and media critiques used in business communication.
|
2022-09-11T15:15:16.350Z
|
35,412,576 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1053/J.JFAS.2007.10.008",
"MAG": "2045896761",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Early mobilization exercises are advocated following Achilles tendon (AT) repair, but forces on the repair during passive range of motion are unknown. The extent to which these forces change with flexion of the knee is also not known. Estimated AT forces were measured using 3 models: cadaveric, uninjured subjects, and in both legs of subjects 6 weeks following unilateral AT repair. For cadaveric testing, estimated AT force was recorded using a force transducer while cycling the ankle from 10 degrees plantarflexion to maximum dorsiflexion at 3 different knee flexion angles (0 degrees , 45 degrees , and 90 degrees ). For in vivo testing, subjects were seated in an isokinetic dynamometer, and their ankles passively cycled from plantarflexion to dorsiflexion with the knee extended and flexed 50 degrees . Passive plantarflexion moment recorded by the dynamometer was converted to AT force by estimating the AT moment arm. In the cadaveric model, knee flexion reduced estimated AT forces during dorsiflexion by more than 40% (P < .036). In vivo testing showed that estimated AT force was reduced in knee flexion in healthy subjects (P < .001) and in the uninvolved leg AT repair subjects (P = .021), but not in the AT repaired leg (P = .387). Normal AT showed a marked reduction in estimated AT force with knee flexion which was not present in repaired AT. This could be because of elongation of the repair, causing more slack in the tendon that would need to be taken up before force transmission occurs. ACFAS Level of Clinical Evidence: 4.
|
2022-09-21T14:25:11.455Z
|
5,107,515 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/ic800513t",
"MAG": "1997700486",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Knowledge of the coordination chemistry and reactivity of isocyanide ligands in transition-metal complexes forms the basis for understanding the adsorption and reactions of isocyanides on metal surfaces. In this overview, we explore reactions (often catalytic) of isocyanides adsorbed on metal surfaces that reflect their patterns of reactivity in metal complexes. We also examine applications of isocyanide adsorption to the stabilization of metal nanoparticles, the functionalization of metal electrodes, and the creation of conducting organic-metal junctions in molecule-scale electronic devices.
|
2022-12-03T17:00:23.502Z
|
25,123,614 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1073/PNAS.0403198102",
"MAG": "2099298455",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We investigated the functions of Akt during vascular development and remodeling by using an inducible endothelial cell-specific driver of the dominant-active myrAkt. We found that sustained signaling in response to overexpression of myrAkt led to embryonic lethality, edema, and vascular malformations. In addition to the morphological malformations, the vascular phenotype was consistent with a failure in remodeling, such that the normal patterning and vessel hierarchy was disturbed. Examination of the well studied retinal vasculature during the remodeling phases revealed that transient expression of myrAkt was capable of altering the normal response to oxygen-induced remodeling without causing vascular malformations. These findings suggest that physiological levels of Akt signaling modulated microvascular remodeling and support the hypothesis that, although Akt may be required for vascular growth and homeostasis, appropriate down-regulation is also an essential aspect of normal vascular patterning.
|
2022-12-20T04:09:31.107Z
|
145,481,728 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1521/JSCP.23.2.260.31022",
"MAG": "2128089267",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract Previous research has established an inverse relationship between materialism and psychological well-being (e.g., Belk, 1984). To test the hypothesis that the link between materialism and affect is due in part to an individual's level of self-presentational concern, American college students ( N = 297) completed the Richins and Dawson (1992) measure of materialism, the Brief Fear of Negative Evaluation Scale (FNE), the Social (SAI) and Personal (PAI) Identity Subscales of the Aspects of Identity Questionnaire, and the Brief Measures of Positive and Negative Affect Scales. Results indicated that the significant relationship between materialism and negative affect disappeared when FNE or SAI were statistically controlled, and that the significant relationship between materialism and positive affect disappeared when FNE was statistically controlled. Results are discussed in relation to other research that has explored reasons why materialism is related to lower level of psychological well-being.
|
2022-12-17T11:59:24.255Z
|
192,514,055 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.12957/REVMAR.2014.13756",
"MAG": "2043053276",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
DARNTON, Robert. Poesia e policia: redes de comunicacao na Paris do seculo XVIII. Traducao Rubens Figueiredo. Sao Paulo, Companhia das Letras, 2014.
|
2022-12-30T18:10:49.499Z
|
191,258,868 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.22409/ANTROPOLITICA2012.0I33.A138",
"MAG": "1515479673",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A danca das regras: a invencao dos estatutos e o lugar do respeito nas gafieiras cariocas O presente artigo versa sobre a constituicao dos “estatutos da gafieira”, quadro de regras situado na entrada e no salao da Gafieira Estudantina, famosa casa de danca localizada na Praca Tiradentes. Buscam-se identificar os processos de construcao moral das ambiencias urbanas e as praticas sociais cotidianas relacionadas a danca social no Centro do Rio de Janeiro. Nesses ambientes, a ideia de “respeito” se impoe como categoria fundamental na conformacao de um genero particular de divertimento associado a metropole carioca. Nesse contexto, as gafieiras promovem um encontro singular entre a danca de salao, a musica dos conjuntos e orquestras e a administracao familiar comandada por imigrantes galego-espanhois. Por meio de um sofisticado quadro de regras, que define modos de vestir e de se comportar, as gafieiras dramatizam uma delicada hospitalidade altamente ritualizada e complexas relacoes entre os chamados mundos da arte, configurando-se como um espaco de convergencia interclasse.
|
2022-03-05T12:52:15.563Z
|
164,570,799 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3366/MOD.2017.0172",
"MAG": "2620608257",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Aside from the familiar story of Vorticists and Imagists before the war, no detailed analysis of manifestos in Britain (or Ireland) exists. It is true that, by 1914, there had been such an upsurge in manifesto writing that a review of BLAST in The Times (1 July 1914) began: ‘The art of the present day seems to be exhausting its energies in “manifestoes.”’ But after the brief fire ignited by the arrival of Italian Futurism died out, Britain again became a manifesto-free zone. Or did it? While a mania for the militant genre did not take hold in Britain and Ireland the same way it did in France, Italy, Germany, or Russia, the manifesto did enjoy a small but dedicated following that included Whistler, Wilde, and Yeats; Patrick Geddes and Hugh MacDiarmid; Wyndham Lewis and Ezra Pound; Dora Marsden and Virginia Woolf; and Auden, MacNeice, and Spender. Through these and other figures it is possible to trace the development of a manifesto tradition specific to Britain and Ireland.
|
2022-03-06T21:06:43.819Z
|
22,055,919 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3748/WJG.V10.I23.3528",
"MAG": "309051634",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
AIM
To study the effect of environmental hyperthermia on gastrin, somatostatin and motilin in rat ulcerated antral mucosa.
METHODS
Forty-two Wistar rats were equally divided into six groups, according to the room temperature (high and normal) and the treatment (acetic acid, normal saline and no treatment). Levels of gastrin, somatostatin and motilin in rat ulcerated antral mucosa were measured with a radioimmunoassay method.
RESULTS
The average temperature and humidity were 32.5 degrees and 66.7% for the high temperature group, and 21.1 degrees and 49.3% for the normal temperature group, respectively. Gastric ulcer model was successfully induced in rat injected with 0.05 mL acetic acid into the antrum. In rats with gastric ulcers, the levels of gastrin and motilin increased, whereas the somatostatin level declined in antral mucosa, compared with those in rats treated with normal saline and the controls. However, the change extent in the levels of gastrin, motilin and somatostatin in antral mucosa was less in the high temperature group than in the normal temperature group.
CONCLUSION
The levels of gastrin, somatostatin and motilin in rat ulcerated antral mucosal tissue remain relatively stable in a high temperature environment, which may relate to the equilibration of the dynamic system.
|
2022-07-01T00:50:29.005Z
|
52,018,964 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2312/PE/VE2007Short/021-026",
"MAG": "2461602618",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We present a novel stereoscopic projection system. It combines all the advantages of modern single-chip DLP technology - attractive price, great brightness, high contrast, superior resolution and color quality - with those of active stereoscopy: invariance to the orientation of the user and an image separation of nearly 100. With a refresh rate of 60 Hz per eye (120 Hz in total) our system is flicker-free even for sensitive users. The system permits external projector synchronisation which allows to build up affordable stereoscopic multi-projector systems, e.g., for immersive visualisation.
|
2022-09-13T22:55:12.569Z
|
221,276,541 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1101/2020.08.20.258764",
"MAG": "3076541902",
"PubMedCentral": "7902599"
},
"license": "CCBY",
"status": "GREEN",
"url": "https://link.springer.com/content/pdf/10.1007/s00497-020-00400-1.pdf"
}
|
Key message Arabidopsis pollen transcriptome analysis revealed new intergenic transcripts of unknown function, many of which are long non-coding RNAs, that may function in pollen-specific processes, including the heat stress response. Abstract The male gametophyte is the most heat sensitive of all plant tissues. In recent years, long noncoding RNAs (lncRNAs) have emerged as important components of cellular regulatory networks involved in most biological processes, including response to stress. While examining RNAseq datasets of developing and germinating Arabidopsis thaliana pollen exposed to heat stress (HS), we identified 66 novel and 246 recently annotated intergenic expressed loci (XLOCs) of unknown function, with the majority encoding lncRNAs. Comparison with HS in cauline leaves and other RNAseq experiments indicated that 74% of the 312 XLOCs are pollen-specific, and at least 42% are HS-responsive. Phylogenetic analysis revealed that 96% of the genes evolved recently in Brassicaceae . We found that 50 genes are putative targets of microRNAs and that 30% of the XLOCs contain small open reading frames (ORFs) with homology to protein sequences. Finally, RNAseq of ribosome-protected RNA fragments together with predictions of periodic footprint of the ribosome P-sites indicated that 23 of these ORFs are likely to be translated. Our findings indicate that many of the 312 unknown genes might be functional and play a significant role in pollen biology, including the HS response.
|
2022-11-25T00:07:39.667Z
|
52,269,655 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2147/CMAR.S166417",
"MAG": "2889311395",
"PubMedCentral": "6124794"
},
"license": null,
"status": null,
"url": null
}
|
Objective To explore the value of carcinoembryonic antigen (CEA) and carbohydrate antigen 19-9 (CA19-9) in predicting downstaging to stage 0–I cancer after neoadjuvant chemoradiotherapy (nCRT) in locally advanced rectal cancer. Materials and methods We respectively investigated pretreatment CEA, pretreatment CA19-9, posttreatment CEA, posttreatment CA19-9, pre–post-CA19-9 ratio, and pre–post-CEA ratio in 674 patients with locally advanced rectal cancer receiving nCRT and determined the patients’ thresholds by using the receiver operating characteristic curve analysis. The association between downstaging (stage 0–I after nCRT), pathological complete response, and clinicopathological parameters was evaluated using the Pearson χ2 test. The clinicopathological parameters which were found to be significantly associated with downstaging were analyzed by logistic regression models and were incorporated into a scoring system. Results Multivariate analysis showed that pretreatment CA19-9 level, posttreatment CEA level, pre–post-CEA ratio, and pre–post-CA19-9 ratio were significantly correlated with downstaging. Area under the curve of the scoring system was higher than that of parameters alone. Conclusion The 4-factor scoring system with CA19-9 level, posttreatment CEA level, pre– post-CEA ratio, and pre–post-CA19-9 ratio is of more value in predicting downstaging to stage 0–I patients with locally advanced rectal cancer after nCRT than using the parameters alone.
|
2022-12-15T23:35:26.336Z
|
135,837,575 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1515/NTREV-2014-0022",
"MAG": "1979050618",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Nanotechnology has been considered as a main hub for the convergence and multidisciplinarity of research fields. Since it emerged, a number of researchers with a variety of backgrounds, including, but not limited to, chemistry, biology, and physics, have converged in this academic melting pot, where synergetic designs of merging multiple principles have been conducted to generate substantial and unprecedented outputs. Based on this interdisciplinary nature, nanotechnology plays a central role nowadays as a bridge to interconnect multiple scientific boundaries. During the convergence in nanotechnology, however, there were unexpected challenges and debates that suppressed the progress of the research development. For example, the integration of different scientific disciplines that were already established in their own fields sometimes had to face troubles owing to the lack of gold standards and clarified definitions. In some cases, reproducibility of the research results was doubted. One suitable example is the case of nanoparticle syntheses. The shape and size of certain types of nanoparticles were often unable to be systematically controlled as reported in literature. The era of uncertainty of nanotechnology, however, is almost over. The gold standards in a variety of fields of nanotechnology are being set up, and the necessary definitions have been prepared, or at least they are ongoing. For example, there are ongoing activities on the creation of the systematic nomenclature of nanomaterials. The systematic and worldwide evaluation of the toxicity of nanomaterials is also in progress. The development of molecular spectroscopy has clearly elucidated the role of trace impurities in synthesis of nanoparticles, which had not been carefully discussed in conventional chemical reactions. Based on such accomplishments today, nanotechnology has not only consolidated its territory as an independent research area but also expanded to divergent areas as a starting point. That is, nanotechnology does not simply merge things together just to see something new anymore, but has begun to provide divergent views and scopes to researchers to better understand and investigate their own sciences. The reviews in this special issue distinctly demonstrate both the convergent and divergent aspects of nanotechnology, by reporting the recent studies and results in their own fields in view of nanotechnology. The investigation of perovskite-type superconducting copper oxides by electron microscopy and diffraction is explained by Oku, where nanotechnology certainly provides a stateof-the-art tool for materials science and physics. The conventional photonics in combination of nanotechnology for the investigation of DNA is outlined by Bregadze et al., where nanotechnology is taken advantage of for biological investigation. The modeling of mass transfer at nanoscale is demonstrated by Kalinitchev, which is an exemplary review of using nanotechnology for investigating theoretical physics. Lee’s review on the silver nanomaterials for the detection of chemical and biological targets deals with how new nanomaterials can be utilized for practical purposes in our lives, with respect to both chemistry and biology. Finally, in a research highlight, the advantages of noble metal nanoparticle catalysts over the conventional ones are reviewed in association with their synthetic methods by Sergeev et al., which obviously show that chemistry can also be an ultimate destination from nanotechnology based on its divergence. All these articles provide excellent demonstrations of advances in diverging nanotechnology heading to the distinctive, major sciences, such as materials science, biology, physics, and chemistry. This collection indicates that such divergence of nanotechnology is definitely noticeable, as a part of the scientific research orientation. As the beginning of convergence of nanotechnology showed troubles, however, the effort to understand the conventional sciences through the window of nanotechnology may also have potential difficulties. Plenty of discussions and communications would be needed to guide researchers in an appropriate way in the future, and I believe that this special issue could be a good point to begin with.
|
2022-02-09T11:29:17.930Z
|
42,684,377 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/jhrm.5600240204",
"MAG": "2069416662",
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},
"license": null,
"status": null,
"url": null
}
|
INTRODUCTION Risk managers’ days are consumed with regulatory compliance, accreditation requirements and day-to-day crises. There may not be a lot of time left to manage claims. Whether responsible for a small number of claims or several hundred, it is important for risk managers to have monitoring processes in place to help ensure the best possible outcome. Claims management tools and processes can assist in managing professional and general liability claims. Large health systems that acquire new facilities may be faced with the assumption of past liabilities, resulting in the management of various types of claims with different insurance programs. Smaller community hospitals may have had frequent changes in their insurance programs presenting challenges in appropriately sorting and managing the applicable coverages for claims. Claims management may involve full insurance or self-insurance or a mixture of both. There may be some policy periods with the primary coverage being self-insured with commercial excess insurance or primary insurance with no excess. The insurance programs may vary between occurrence and claims made. With so many different variations of applicable insurance programs, a process to manage claims and risk is important.
|
2022-02-12T02:42:59.473Z
|