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201,735,159 |
{
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"DOI": "10.2478/ausm-2019-0012",
"MAG": "2969814670",
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},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://www.sciendo.com/pdf/10.2478/ausm-2019-0012"
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|
Abstract The purpose of this paper is to introduce a class of functions ℱλ, λ ∈ [0, 1], consisting of analytic functions f normalized by f(0) = f´(0) − 1 = 0 in the open unit disk U which satisfies the subordination condition that zf′(z)/{ (1-λ)f(z)+λz }≺q(z), z∈𝕌, $${\rm{z}}f'\left( {\rm{z}} \right)/\left\{ {\left( {1 - \lambda } \right){\rm{f}}\left( {\rm{z}} \right) + \lambda {\rm{z}}} \right\} \prec {\rm{q}}\left( {\rm{z}} \right),\,\,\,\,\,{\rm{z}} \in {\rm{\mathbb{U},}}$$ where q(z)=1+z2+z ${\rm{q}}\left( {\rm{z}} \right) = \sqrt {1 + {{\rm{z}}^{\rm{2}}}} + {\rm{z}}$ . Some basic properties (including the radius of convexity) are obtained for this class of functions.
|
2022-10-25T11:31:07.189Z
|
127,421,685 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1029/2000JB900437",
"MAG": "749892150",
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},
"license": null,
"status": null,
"url": null
}
|
The Earth's magnetic field can be subdivided into core and crustal components and we seek to characterize the crustal part through its spatial power spectrum (R(sub l)). We process vector Magsat data to isolate the crustal field and then invert power spectral densities of flight-local components along-track for R(sub l) following O'Brien et al. [1999]. Our model (LPPC) is accurate up to approximately degree 45 (lambda=900 km) - this is the resolution limit of our data and suggests that global crustal anomaly maps constructed from vector Magsat data should not contain features with wavelengths less than 900 km. We find continental power spectra to be greater than oceanic ones and attribute this to the relative thicknesses of continental and oceanic crust.
|
2022-11-11T08:22:25.644Z
|
236,213,352 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/cancers13143417",
"MAG": null,
"PubMedCentral": "8303518"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2072-6694/13/14/3417/pdf?version=1625734486"
}
|
Simple Summary The classical approach to study the immune response against a tumor was mixing immune cells with tumor cell suspensions in several experimental settings. These models lack the appropriate tissue architecture in which the immune response takes place and do not consider other cellular and extracellular players of the tumor microenvironment essential to understand the anti-tumor immune response. Thus, to confirm in vitro data, in vivo experiments have been extensively performed, using animal models that may not fully reproduce what happens in humans. Indeed, in animal-based studies, tumors are artificially generated in a short time, and immune cell subsets and receptor-ligands pairs, involved in tumor cells recognition by the immune system, are often different from human counterparts. To reduce the number of animals used, and possibly replace animal models, alternative methods of culture have been developed. Herein, some of these approaches will be described, highlighting their advantages and disadvantages, focusing on natural killer cells as the first line of anti-tumor effector cells able to contrast tumor growth. Abstract Several approaches have shown that the immune response against tumors strongly affects patients’ clinical outcome. Thus, the study of anti-tumor immunity is critical to understand and potentiate the mechanisms underlying the elimination of tumor cells. Natural killer (NK) cells are members of innate immunity and represent powerful anti-tumor effectors, able to eliminate tumor cells without a previous sensitization. Thus, the study of their involvement in anti-tumor responses is critical for clinical translation. This analysis has been performed in vitro, co-incubating NK with tumor cells and quantifying the cytotoxic activity of NK cells. In vivo confirmation has been applied to overcome the limits of in vitro testing, however, the innate immunity of mice and humans is different, leading to discrepancies. Different activating receptors on NK cells and counter-ligands on tumor cells are involved in the antitumor response, and innate immunity is strictly dependent on the specific microenvironment where it takes place. Thus, three-dimensional (3D) culture systems, where NK and tumor cells can interact in a tissue-like architecture, have been created. For example, tumor cell spheroids and primary organoids derived from several tumor types, have been used so far to analyze innate immune response, replacing animal models. Herein, we briefly introduce NK cells and analyze and discuss in detail the properties of 3D tumor culture systems and their use for the study of tumor cell interactions with NK cells.
|
2022-12-11T00:12:00.403Z
|
54,853,635 |
{
"externalids": {
"ACL": null,
"ArXiv": "1801.02588",
"DOI": "10.1093/mnras/sty145",
"MAG": "2783374766",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "http://arxiv.org/pdf/1801.02588"
}
|
The last decade has seen the detection of fast moving stars in the Galactic halo, the so-called hypervelocity stars (HVSs). While the bulk of this population is likely the result of a close encounter between a stellar binary and the supermassive black hole (MBH) in the Galactic Centre (GC), other mechanims may contribute fast stars to the sample. Few observed HVSs show apparent ages which are shorter than the flight time from the GC, thereby making the binary disruption scenario unlikely. These stars may be the result of the breakup of a stellar triple in the GC which led to the ejection of a hypervelocity binary (HVB). If such binary evolves into a blue straggler star due to internal processes after ejection, a rejuvenation is possible that make the star appear younger once detected in the halo. A triple disruption may also be responsible for the presence of HVBs, of which one candidate has now been observed. We present a numerical study of triple disruptions by the MBH in the GC and find that the most likely outcomes are the production of single HVSs and single/binary stars bound to the MBH, while the production of HVBs has a probability ≲1% regardless of the initial parameters. Assuming a triple fraction of ≈10% results in an ejection rate of ≲1 Gyr−1, insufficient to explain the sample of HVSs with lifetimes shorter than their flight time. We conclude that alternative mechanisms are responsible for the origin of such objects and HVBs in general.
|
2022-12-14T07:05:58.101Z
|
354,844 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/BI00361A001",
"MAG": "1988569168",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
31P and 2H solid-state NMR studies of dry trehalose (TRE) and 1,2-dipalmitoyl-sn-phosphatidylcholine (DPPC) mixtures are reported. 31P spectra are consistent with a rigid head group above and below the calorimetric phase transition for both dry DPPC and a dry 2:1 TRE/DPPC mixture. In addition, 2H spectra of DPPC labeled at the 7-position of the sn-2 chain (2[7,7-2H2]DPPC) show exchange-narrowed line shapes with a width of 120 kHz over the temperature range 25-75 degrees C. These line shapes can be simulated with a model involving two-site jumps of the deuteron. In contrast, the 2H NMR spectrum of a dry 2:1 TRE/2[7,7-2H2]DPPC mixture above the phase transition (Tc = 46 degrees C) is narrowed by a factor of approximately 4 to a width of 29 kHz. Simulation of this spectrum requires a model involving four-site jumps of the deuteron and is indicative of highly disordered lipid acyl chains similar to those found in the L alpha-phases of hydrated lipids. Thus, TRE/DPPC mixtures above their transition temperatures exist in a new type of liquid crystalline like phase, which we term a lambda-phase. The observation of the dynamic properties of this new phase indicates the mechanism by which anhydrobiotic organisms maintain the integrity of their membranes upon dehydration.
|
2022-12-19T15:33:10.576Z
|
210,005,431 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1748-0221/14/09/C09045",
"MAG": "2977952365",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The high luminosity expected from the HL-LHC will be a challenge for the CMS detector. The increased rate of particles coming from the collisions and the radioactivity induced in the detector material could cause significant damage and result in a progressive degradation of its performance. Simulation studies are very useful in these scenarios as they allow one to study the radiation environment and the impact on detector performance. Results are presented for CMS RPC stations considering the operating conditions expected at the HL-LHC.
|
2022-12-23T02:26:27.352Z
|
96,649,063 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1116/1.581870",
"MAG": "2086025958",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We have used scanning tunneling microscopy (STM) and Auger electron spectroscopy to characterize B/Si(001) surface structures and the dependence of their density and location on high-temperature annealing. While annealing of heavily B-doped Si(001) surfaces is known to result in periodic SB step “fingers” whose density depends strongly on temperature, we have found that, on the time scale of formation of the step fingers, the atomic-scale properties of these surfaces are not altered significantly by high-temperature processing. B structures were found to decorate SA step edges. Hot STM was used to study the dynamics of finger formation and the interaction between atomic-scale B/Si(001) structures and fluctuating dimer rows.
|
2022-09-02T09:29:16.367Z
|
120,156,986 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1467-9892.1994.TB00175.X",
"MAG": "1998979007",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
. The paper is devoted to random aggregation of multivariate autoregressive moving-average (ARMA) processes. We derive second-order characteristics of random aggregate models. We show that random aggregation preserves the ARMA structure. Moreover, we specify a functional relation between the initial model poles and aggregate ones. We then examine the case of univariate ARMA processes. Theorem 4 shows that, if the initial process is ARMA(p, q), the random aggregate process is an ARMA(p*, q*) model with p* at most equal to p; * depends, among other things, on the sampling distribution L. This theorem generalizes the well-known results on the topic of time interval aggregation without overlapping.
|
2022-09-12T08:59:27.849Z
|
154,688,478 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5539/IES.V1N1P69",
"MAG": "2075399820",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
As for the heated problem of the Internationalized Higher Education (IHE), the thesis makes a deep research stating the tendency of IHE and focusing on the strategy and the issues that must be paid more attention to in the realization of the Internationalized Higher Education (IHE).
|
2022-10-14T00:57:08.428Z
|
245,770,242 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/tropej/fmab102",
"MAG": null,
"PubMedCentral": "8690266"
},
"license": null,
"status": "BRONZE",
"url": "https://academic.oup.com/tropej/article-pdf/67/6/fmab102/41854910/fmab102.pdf"
}
|
Abstract Objective The aim of this study was to compare the clinical and laboratory findings in SARS-CoV-2 (COVID-19) with those of other respiratory viruses in critically ill children. Methods It is a single center retrospective descriptive study conducted in a 32-bed pediatric intensive care unit (PICU). Our study was performed in Ankara City Hospital, Ankara, Turkey, between March 1, 2020, and March 1, 2021. Demographic and clinical characteristics of the patients were collected, and we recorded antibiotic use, antiviral treatments, respiratory and extracorporeal supports, PICU stay, and survival rates. Results A total of 202 pediatric patients who tested positive for either COVID-19 or for another respiratory virus (RVP) were included in the study. Seventy-two patients were COVID-19 positive. The median age of COVID-19 positive patients and RVP positive patients was 97 and 17 months, respectively. Hypoxia was much more common in patients with RVP than in COVID-19 patients. Low oxygen saturation in arterial blood (SaO2), increased oxygen saturation index (OSI), and fraction of inspired oxygen (FiO2) needs were more significant in RVP patients than in COVID-19 patients. Respiratory support therapies, such as high-flow nasal cannula (HFNC) and non-invasive ventilation (NIV), were used more frequently in RVP patients than in COVID-19 patients. Conclusion It is important to distinguish between Covid-19 and RVP cases in order to prioritize intensive care needs in these patients. In addition, non-Covid diseases should not be left aside in the pandemic and appropriate care should be provided to them.
|
2022-10-19T14:37:00.609Z
|
226,331,735 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.12737/2587-9111-2020-64-72",
"MAG": "3093497721",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
An integrated approach to the analysis of the potential of the phases and participants of the reproduction process at the stage of forming the product policy of a machine-building enterprise and its development in critical directions is proposed. This allows, from a unified standpoint on the mismatch between the target and the achieved level of potential, to identify critical participants in the reproduction cycle, whose internal capabilities are insufficient to optimize the economic result from the product program and to identify the contribution of each participant based on the analysis of the hierarchy of cause-and-effect relationships of the variables of the utility function with the elements of their potential, as well as assess and select local development strategies for critical participants. The materials of the article can be useful to specialists dealing with the problems of developing a product policy and developing enterprises.
|
2022-12-09T21:08:09.239Z
|
7,459,407 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1371/journal.pgen.0030190",
"MAG": "2094174059",
"PubMedCentral": "2039766"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.0030190&type=printable"
}
|
Genome-wide association scans (GWASs) using single nucleotide polymorphisms (SNPs) have been completed successfully for several common disorders and have detected over 30 new associations. Considering the large sample sizes and genome-wide SNP coverage of the scans, one might have expected many of the common variants underpinning the genetic component of various disorders to have been identified by now. However, these studies have not evaluated the contribution of other forms of genetic variation, such as structural variation, mainly in the form of copy number variants (CNVs). Known CNVs account for over 15% of the assembled human genome sequence. Since CNVs are not easily tagged by SNPs, might have a wide range of copy number variability, and often fall in genomic regions not well covered by whole-genome arrays or not genotyped by the HapMap project, current GWASs have largely missed the contribution of CNVs to complex disorders. In fact, some CNVs have already been reported to show association with several complex disorders using candidate gene/region approaches, underpinning the importance of regions not investigated in current GWASs. This reveals the need for new generation arrays (some already in the market) and the use of tailored approaches to explore the full dimension of genome variability beyond the single nucleotide scale.
|
2022-12-17T12:27:34.270Z
|
15,356,994 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4314/ovj.v6i3.13",
"MAG": "2560673013",
"PubMedCentral": "5155138"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.ajol.info/index.php/ovj/article/download/149283/138782"
}
|
A 4-year-old male Japanese Shiba Inu presented with recurrent chylothorax. The thoracic duct was successfully imaged using computed tomography after the injection of an iodine contrast agent into the subcutaneous tissue surrounding the anus. The thoracic duct was successfully ligated and pericardectomy performed via an open thoracotomy. Pleural effusion improved but relapsed a week after the surgery. A second lymphography revealed a collateral thoracic duct that was not detected during the first lymphography. The collateral duct was ligated and chylothorax was resolved after the second surgery. The lymphography applied in this study was minimally-invasive and easily provided images of the thoracic duct in a dog with chylothorax.
|
2022-12-20T11:33:02.310Z
|
17,763,184 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1145/2350716.2350749",
"MAG": "1997311079",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper presents an adaptation of the Ant System method to find the optimal control input for blood glucose regulation using Model Predictive Control (MPC). The Ant System optimization method was implemented to solve a linear MPC problem and performance was compared with the interior point method for optimization. The Ant System was found to perform well for the linear MPC problem and has the advantage over the interior point method as it can extended for use with non-linear MPC problems.
|
2022-12-22T15:05:02.747Z
|
23,546,704 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1098/rspb.1998.0516",
"MAG": "2027950004",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc1689375?pdf=render"
}
|
Costs of reproduction include costs of producing eggs and of mating itself. In the present study, we made an experimental investigation of costs of reproduction in the Mediterranean fruit fly (medfly, Ceratitis capitata). We demonstrated that virgins live longer than non–virgin females. However, in strong contrast to most findings within the Diptera, non–virginity had no detectable effect on egg production. Therefore the increased longevity of the virgin females cannot be attributed to an increase in egg production in non–virgin females, and instead indicates a cost of mating. A comparison of the life spans of normal females and those sterilized by low doses of X–irradiation, revealed an additional cost of egg production. There were no significant differences in remating levels between females that did and did not lay eggs, showing that the cost of producing eggs is independent of mating frequency. Medfly females therefore suffer a decrease in survival as a result of egg production and of mating, and these costs are independent of one another. To put our results into context, we reviewed the existing literature on the effects of mating on longevity, egg production and sexual receptivity for 64 species of Diptera, and examined the pattern of mating effects that emerged.
|
2022-12-26T05:56:11.815Z
|
25,775,885 |
{
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"ArXiv": null,
"DOI": "10.1109/ESTEL.2012.6400203",
"MAG": "1967092297",
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},
"license": null,
"status": null,
"url": null
}
|
The aim of this paper is to present different launch vehicle options in order to serve a wide range of satellites markets. These options are achieved through different vehicle architectures that can be synthesized by the following points: ; VEGA baseline configuration capable to serve mainly EO satellites on different mass ranges and arrangements; according to current performance capability we address payloads ranging from few kilograms up to 2 tons in LEO ; VEGA consolidation (VEGA-E1) with improved stages and associated technologies, this configuration allows a 2.4 tons in LEO payload ; VEGA evolution improved (VEGA-E2) could be capable to put 3.1 tons payload in LEO with 3 m fairing size ; VEGA evolution with an advanced propulsion module could serve ISS as well as high altitude missions; this version will be equipped with a debris mitigation system representing a breakthrough in launch vehicle operations. This vehicle constitute also a very low cost solar planets exploration system. For each vehicle a technology summary, a performance map and a mission profile will be shown. Launch vehicle design drivers for every option are the same that made VEGA baseline a mission success development programme, which are: LV launch service cost, customer & payload comfort, mission flexibility and the commonality with the Ariane family. Regarding the last point, the complementary with respect to existing family fleet (Soyuz and Ariane) has been considered in order to make the best possible synergy among launch systems, also completing the European launch capability. It is worth to note that VEGA launchers will be capable to serve both consolidated and emerging satellite markets. In particular, a service market-matrix showing benefits for citizens worldwide will be shown and explicated, also taking into consideration the contribution to the global space value chain (i.e. impacts on everyday life, human activities monitoring, natural disaster mitigation and so on). Finally a roadmap to address future developments will be proposed and an overall operational scenario will be presented.
|
2022-02-12T18:03:54.989Z
|
243,811,088 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1364/josaa.440863",
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"status": null,
"url": null
}
|
Autofocusing Airy-like beams have been designed based on the self-accelerating beams along arbitrary polynomial paths. The evolutions of the autofocusing beam in free space and turbulent atmosphere have been studied. Results show that the energy concentration of the autofocusing beam near the focal plane has a close relationship with its accelerating trajectory. The spot size of the autofocusing beam in the focal plane varies with the acceleration trajectory. The influence of turbulence on different autofocusing beams is different and has a relation with the degree of the curvature of the accelerating beam. The autofocusing beam propagating along a small curvature path has better resistance against turbulence.
|
2022-02-25T07:45:34.892Z
|
144,124,470 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3989/HISPANIA.2007.V67.I226.53",
"MAG": "2008063353",
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},
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"status": null,
"url": null
}
|
This article analyses the appearance and developement of the pressure group « Damas Rojas », linked with radical republicanism, which was founded in Madrid by the Barcelona group of the same name, so crucial during the «Semana Tragica». An analysis is made of the precedents, protagonists and activities carried out by the group as well as the reactions that these provoked. An evaluation is made of the group as an example of a partially trangressing collective, which provided an important experience in the exercise of citizenship for these women, and trough which they gained a voice and were able to express their vindications in favour of social and political rights.
|
2022-12-10T18:01:39.712Z
|
7,748,096 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1287/ISRE.1040.0027",
"MAG": "2117826245",
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},
"license": null,
"status": null,
"url": null
}
|
Internet fraud has been on the rise in online consumer-to-consumer (C2C) auction markets, posing serious challenges to people's trust in electronic markets. Among various remedies to promote trust and reduce trader's risk, online escrow service has been proposed as a trusted third party to protect online transactions from Internet fraud. However, whether an escrow service constitutes a viable business model for a trusted third party to effectively block Internet fraud remains an open question. This research proposes a dynamic game model for online traders and a profit maximization model for the escrow service provider. Through the investigation of the optimal strategies of online traders, we explore the relationships among traders' decision making, escrow service fee rates, and adoption rates. We reveal the demand for escrow services and establish the optimal pricing rule for the escrow service provider. A numerical study based on the theoretical analysis is conducted to provide detailed guidelines of the model application for an escrow service provider and to explore if the escrow service is a viable business model in C2C auction markets.
|
2022-12-21T03:50:25.916Z
|
2,230,093 |
{
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"ArXiv": null,
"DOI": "10.1002/smll.200700888",
"MAG": "2170649768",
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},
"license": null,
"status": null,
"url": null
}
|
State Key Laboratory of Electroanalytical Chemistry, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, Jilin 130022, People’s Republic of China, and Graduate School of the Chinese Academy of Sciences, Beijing, 100039, People’s Republic of China We also examine the influence of the amount of reducing agent and the diameter of nanoparticles on SERS spectra. When the concentration of ascorbic acid was decreased from 7.6 mM to 3.6 mM, the SERS spectra collected from the silver/gold microtubes contained dominant a1 vibrational modes even with a deposition time for silver atoms of only 3 min, indicating that an uniform and complete silver shell on gold nanoparticles can be prepared easily by decreasing in the deposition rate of the silver atoms. As the deposition time of silver shells increases, the SERS intensity of 4-ATP also increases (Figure S1 shown in supporting information), which can be due to an increased nanoparticles diameter.
|
2022-12-20T04:13:09.765Z
|
127,245,364 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.7146/politica.v47i2.131468",
"MAG": "829973611",
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},
"license": null,
"status": "GOLD",
"url": "https://tidsskrift.dk/politica/article/download/131468/176956"
}
|
Den svenska välfärdsstaten har under senare år reformerats på ett sätt som skapat omfattande valfrihetssystem för tjänster inom vård, skola och omsorg. Motivet till detta har varit att individualisera tjänsterna på ett sätt som ger ökad personlig frihet samt konkurrens som leder till högre effektivitet och bättre kvalitet. Men är just valfrihet på kvasi-marknader det enda sättet att nå detta mål? Denna artikel undersöker hur medskapande (co-production) kan användas för att nå samma eller liknande mål. Med hjälp av resultat från ett forskningsprojekt undersöks möjligheterna med medskapande med hänsyn till dess olika effekter på produktionen av välfärdstjänster och vad Marshall kallade det sociala medborgarskapet. Resultatet visar att både kvasi-marknader och medskapande har sina begränsningar i hur de fungerar – särskilt i relation till marginaliserade grupper – men att medskapande har möjlighet att förena individualisering med social sammanhållning om den politiska viljan finns.
|
2022-07-04T21:27:41.162Z
|
232,774,461 |
{
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"ArXiv": null,
"DOI": "10.3390/ma14071655",
"MAG": null,
"PubMedCentral": "8037605"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/1996-1944/14/7/1655/pdf?version=1617937519"
}
|
The presented studies are focused on the wear resistance and friction coefficient changes of the thermal diffusion (TD) zinc coating deposited on steel. The aim of research was to evaluate the variation in coating properties during dry friction as a result of the method of preparation of the basis metal. The measured properties were compared to those obtained after classic hot-dip (HD) zinc galvanizing—heat treated and untreated. Thermal diffusion zinc coatings were deposited in industrial conditions (according to EN ISO 17668:2016-04) on disc-shaped samples. The results obtained during the tribological tests (T11 pin-on-disc tester) were analysed on the basis of microscopic observations (with the use of optical and scanning microscopy), EDS (point and linear) analysis and microhardness measurements. The obtained results were similar to effects observed after heat treatment of HD zinc coating. The conducted analysis proved that the method of initial steel surface preparation results in changes in the coating’s hardness, friction coefficient and wear resistance.
|
2022-12-12T12:37:54.235Z
|
2,839,475 |
{
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"ArXiv": null,
"DOI": "10.1182/BLOOD.V54.2.477.477",
"MAG": "2413080461",
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"license": null,
"status": null,
"url": null
}
|
Previous studies in dogs given 1 200 R and a hemopoietic graft from DLA-identical littermates have shown that marrow graft rejection generally does not occur when the recipient is untransfused (58 of 59 achieved sustained engraftment) but is seen after a single transfusion of blood from the marrow donor on day -10 (13 of 18 rejected) and even after multiple transfusions of random blood (3 of 1 1 rejected). This study extends those initial observations by determining the incidence of rejection of DLA-identical littermate marrow grafts following administration of different cells from the marrow donor on days 24, 1 7, and 10 prior to transplantation. Using this protocol, the following results and conclusions were established. (1 ) All 1 9 dogs given transfusions of whole blood rejected their grafts. This 1 00% incidence of rejection after three transfusions mdicates that more than one minor histocompatibility system outside of DLA is involved in transfusion-induced sensitization and subsequent marrow graft rejection. (2) Six dogs given subcutaneous injections of cultured skin epithelial cells rejected their subsequent marrow grafts. Hence, antigens mediating rejection are not restricted to hemopoietic cells but are also expressed on at least one other tissue. (3) Seven of 15 dogs given transfusions of platelet concentrates (“free” of white and red blood cells) rejected the marrow graft, while 8 showed sustained engraftment. (4) Five of 14 dogs given transfusions of red blood cells (free of white blood cells and platelets) rejected the marrow graft, while 9 had sustained engraftment. This suggests that only some (and perhaps none) of the non-DLA antigens responsible for rejection reside on platelets and red blood cells. To definitively answer this question, the current blood cell separation techniques must be improved further to provide pure red blood cells and platelets for transfusion studies. Assays of lymphocytotoxic antibodies. mixed leukocyte culture reactivity. and survival of donor platelets in the recipient did not predict the fate of the subsequent marrow graft. These findings in DLA-identical canine marrow graft recipients are of potential practical importance for planning platelet and red blood cell support of human marrow graft candidates.
|
2022-12-16T01:12:00.449Z
|
45,128,303 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1037/a0017117",
"MAG": "91440547",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
This pilot study explored the associations between parent and adolescent reports of adolescent attachment and glycemic control in adolescents with Type 1 diabetes. We hypothesized that more secure attachment would correlate with more optimal diabetes control. Thirty-one families completed written self-report questionnaires about adolescent attachment, demographic data, and diabetes control. Adolescents and parents reported on their perceptions of adolescents' attachment to mothers and fathers. Mean HbA1c for the sample was 7.6% (SD = 1.14). Mothers' perceptions of adolescents' attachment were significantly correlated with adolescents' hemoglobin A1c (r = -.42, p = .022), indicating that maternal perceptions of more secure attachment was associated with better glycemic control. Neither fathers' perceptions nor adolescents' reports of attachment was significantly correlated with glycemic control. Attachment appears to be associated with glycemic control in this population though the mechanisms are unclear. Mothers' perceptions of attachment had the strongest associations with control, not adolescent reports. Further research is needed to understand the mechanisms through which parent reports of adolescent attachment are associated with glycemic control.
|
2022-12-19T18:43:38.309Z
|
210,863,169 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/all.14194",
"MAG": "3001973652",
"PubMedCentral": null
},
"license": "CCBYNC",
"status": "HYBRID",
"url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/all.14194"
}
|
and Sanofi/Genzyme/Regeneron.
|
2022-12-28T14:54:06.268Z
|
227,274,739 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1751-8369.1995.TB00706.X",
"MAG": "2083582951",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A small mammal collection from the Kolyma region in northeastern Siberia collected by the Norwegian trapper and naturalist Johan Koren between 1915 and 1917 comprises 152 specimens of 17 species. The collection was brought to Norway with Roald Amundsen's “Maud” expedition through the Northeast Passage and has been held by the Zoological Museum, University of Oslo. When comparing the collection with the current distribution of small mammals in the region, it is not possible to detect changes in the small mammal fauna. As several species which are common today are missing in the collection, the collection apparently does not give a complete account of the small mammal fauna in the Kolyma region from 1915 to 1917. This discrepancy can largely be explained by the fact that Koren caught small mammals only in parts of the Kolyma region and not in those areas where the missing species are found in abundance.
|
2022-02-07T23:33:01.054Z
|
74,141,855 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/009286159803200431",
"MAG": "2173789161",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The pharmaceutical industry must always endeavor to collect and evaluate information on efficacy, safety, and quality of drugs, and in a timely manner provide relevant information to medical professionals as well as to patients. Daiichi Pharmaceutical Co. Ltd 's PMS Administration Department developed a drug information database system (Advanced Medical Online Network of Daiichi [AMOND]), and upgraded the system (AMOND-II) in December 1993. This upgraded system included a function for a package insert information system where drug information obtained during development and after launch can be retrieved. From results of analysis of utilization of the new system, it was realized that medical representatives (MRs) and the MR support staff at branch offices need information on only a few specific products, and retrieve package insert information on those products using this system. In contrast, the needs of headquarters staff are not limited to information on specific products and they use this system to obtain information on drugs meeting specific requirements. How package insert information should be provided has been the subject of active discussion. This paper presents the functions of the package insert information system developed at Daiichi Pharmaceutical, its utilization within the company, and Daiichi Pharmaceutical's perspective on the system.
|
2022-02-11T08:21:54.867Z
|
216,495,458 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/00268976.2020.1742935",
"MAG": "3010890155",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://hal.archives-ouvertes.fr/hal-02519071/file/TMPH-2019-0513_Proof_hi%281%29_preprint.pdf"
}
|
In this paper, the non-local density functional theory is used in combination with SAFT-VR, to investigate the pore pressure behaviour of water confined in various nanopores. Due to the efficiency and low computational cost of the method, many configurations and thermodynamic conditions are explored. In particular, capillary condensation and evaporation of water, their impact on the pore pressure, and the effect of surface activation are evaluated. Successive first-order phase transitions of ultra-confined water monolayer are also highlighted. GRAPHICAL ABSTRACT
|
2022-12-30T00:24:23.101Z
|
137,523,923 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21236/ada389094",
"MAG": "335411987",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract : A new class of high temperature metastable oxides (Cerablak(Trademark)) based on aluminum phosphate composition was investigated under this program. The study included further understanding the sol-gel synthetic procedure, the structural evolution of the material from the precursor state to the calcined form, extensive microstructural and spectroscopic characterization of powders, and development of coatings targeted toward Air Force applications. Evidence collected showed that the thermal stability limit for the material is above 1400 deg C in air and the stability is enhanced by the amount of excess aluminum present beyond the 1:1 stoichiometric aluminum phosphate composition. While much of the structural details are still unknown, the presence of Al-O-Al bonds in the amorphous network appears to play an important role in extending the metastability. The hypothesis for the extended metastability has been attributed to low mobility of atoms in the amorphous network which resists crystallization. Thin, dense, and pore-free films were easily deposited on various metal, alloy, and ceramic substrates by a simple dip-coating process. The low mobility of oxygen was demonstrated through pronounced evidence of oxidation protection of stainless steel coupons coated with Cerablak(Trademark). The study also included synthesis of Cerablak(Trademark) in various forms, determination of key properties and investigating its applicability to specific Air Force applications.
|
2022-02-09T10:34:20.328Z
|
57,588,890 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5794/JJOMS.52.366",
"MAG": "2313182811",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Obstructive sleep apnea syndrome (OSAS) is a life-threatening breathing disorder. We describe a patient with micrognathia and OSAS who underwent mandibular advancement by bilateral mandibular distraction osteogenesis. A 36-year-old man had micrognathia due to neonatal bilateral temporomandibular joint ankylosis. He also had severe OSAS. Conservative treatment for OSAS, such as continuous positive airway pressure, had been attempted at another hospital, but was not successful. Before mandibular distraction, sleep apnea was severe; the apnea hyponea index (AHI) was 63, and the Epworth sleepiness scale (ESS) was 8. After distraction, AHI and ESS greatly improved to 8 and 1, respectively. Cephalometric analysis showed that the widths of the upper airways had increased. In conclusion, mandibular advancement by distraction osteogenesis was effecttive for correcting micrognathia associated with OSAS. There has been no relapse of malocclusion and no recurrence of OSAS for 2 years after the operation.
|
2022-02-11T17:51:10.542Z
|
144,597,848 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/001654928603800113",
"MAG": "2045013042",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Results of one set of these measurements were presented as they applied mostly to the English-language newspapers in four differing political venues (one kingdom, Touga; one British colony on the verge of independence, Fiji ; one United States dependency, American Samoa, and one independent island nation, Western Samoa) concluding that there is &dquo;little evidence of systematic inclusion of such material [the ’Inspector General’ content] .1 In fact, &dquo;so-called ’minimum effort’ types of information that which would tend to gravitate normally to a newspaper dominated measurable content, with the top four categories [of eight total] accumulating 75.35 per cent of the total points&dquo; [in the measure] :
|
2022-02-09T06:53:30.856Z
|
142,947,105 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.32734/psikologia.v8i1.2563",
"MAG": "1587184070",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://talenta.usu.ac.id/jppp/article/download/2563/1946"
}
|
Tujuan penelitian ini adalah mendapatkan gambaran resiliensi perantau dari suku Minangkabau yang berwirausaha di Kota Medan. Suku Minangkabau sebagai salah satu suku di Indonesia memiliki budaya merantau. Sebagian besar dilakukan saat merantau ialah berwirausaha. Saat merantau dan berwirausaha akan menghadapi beberapa kesulitan. Dalam berwirausaha dan merantau butuh adanya kemampuan resiliensi. Penelitian ini melibatkan 296 wirausahawan perantau Minangkabau yang bertempat tinggal di Medan. Skala yang digunakan dalam penelitian ini ialah adaptasi dari Resiliency Quotient Test (RQ test ) oleh Reivich dan Shatte (2002). Hasil penelitian menunjukkan mayoritas perantau Minangkabau yang berwirausaha memiliki resiliensi yang tergolong tinggi. Tidak ada perantau Minangkabau yang berwirausaha memiliki resiliensi yang tergolong rendah.
|
2022-02-09T07:47:32.471Z
|
248,464,377 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.24018/ejmed.2022.4.2.1304",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.ej-med.org/index.php/ejmed/article/download/1304/778"
}
|
Since the beginning of the COVID-19 pandemic, many cases of SARS-CoV-2 co-infection with other respiratory pathogens have been reported. These situations may be a source of under-diagnosis leading to the spread of SARS-COV-2. We report the first case of triple infection involving SARS-CoV-2, Adenovirus and Respiratory Syncytial Virus in 4 months old infant. Initially admitted with symptoms of viral bronchiolitis. The aim is to highlight the importance of using multiplex PCR for the syndromic approach of respiratory infections in this pandemic period, especially in children, in order to limit spread of COVID-19 to others.
|
2022-06-24T12:45:05.298Z
|
137,097,951 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/IMNC.2000.872718",
"MAG": "1807588360",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The effect of SF/sub 6/ addition in O/sub 2/ plasma on the etching characteristics of polyimide-one of the promising low-k interlayer dielectrics-has been studied. Plasma etching of polyimide with an O/sub 2//SF/sub 6/ mixture gas is desirable due to the improved etch topography and lowered dielectric constant in spite of reduced etch rate and etching selectivity to SiO/sub 2/ hard mask.
|
2022-09-01T08:49:03.652Z
|
219,767,791 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/cdn/nzaa040_017",
"MAG": "3032872738",
"PubMedCentral": null
},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://academic.oup.com/cdn/article-pdf/4/Supplement_2/17/33312969/nzaa040_017.pdf"
}
|
To investigate the role of bioactive lipids (BAL) in ageing associated disorders such as obesity, type 2 diabetes mellitus, hypertension, coronary heart disease, immune dysfunction and cancer.
We recruited known patients of type 2 diabetes mellitus, hypertension, coronary heart disease, diabetic nephropathy and cancer and collected their blood samples for the study. In these samples the concentrations of various BAL such as linoleic acid, gamma-linolenic acid, dihomo-gamma-linolenic acid, arachidonic acid, alpha-linolenic acid, eicosapentaenoic acid, docosahexaenoic acid and other lipids in their phospholipid fraction was measured. The role of these BAL in these diseases was also studied in animal models of diabetes mellitus and cancer. To evaluate the mechanism of action of BAL, in animal models of type 2 diabetes mellitus and cancer, the expression of NF-kB, IKB, COX-1, COX-2 and LOX and plasma levels of IL-6, TNF, nitric oxide and lipid peroxides was also studied.
Plasma levels of arachidonic acid in the phospholipid fraction was found to be low in all the patients recruited in the study. In some of these patients plasma levels of gamma-linolenic acid, eicosapentaenic acid and docosahexaenoic acid were also found to be altered. But, of all the lipids estimated, arachidonic acid was found to be consistently low in those with obesity, type 2 diabetes mellitus, hypertension, coronary heart disease and cancer. In animal models of type 2 diabetes mellitus, hypertension and cancer, administration of arachidonic acid produced significant amelioration of these conditions suggesting a critical role for this lipid in these diseases. Further studies revealed that arachidonic acid suppresses inflammation and enhanced the formation of lipoxin A4 (LXA4), which is a potent anti-inflammatory compound. A significant suppression of pro-inflammatory genes and restoration of anti-oxidant status to normal.
Based on the results of the present study, ageing associated diseases such as obesity, type 2 diabetes mellitus, hypertension, coronary heart disease, and cancer are inflammatory conditions with low circulating concentrations of arachidonic acid and lipoxin A4. These results imply that appropriate administration of arachidonic acid and lipoxin A4 could be of benefit in ageing and ageing associated diseases.
Nil.
|
2022-11-11T08:15:38.203Z
|
1,233,093 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/jhered/ess029",
"MAG": "2123589275",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://academic.oup.com/jhered/article-pdf/103/4/493/3431864/ess029.pdf"
}
|
We studied the chromosomal distribution of telomere repeats (TTAGGG)(n) in 8 species of Sigmodon (cotton rats) using chromosome paints fluorescent in situ hybridization (FISH) from Sigmodon hispidus. In 2 species with the proposed primitive karyotype for the genus, telomere repeats were restricted to telomeric sites. But in the other 6 species that include 3 with proposed primitive karyotypes and 3 with highly rearranged karyotypes, telomere repeats were found on both telomeric sites and within interstitial telomeric sites (ITSs). To explain the distribution of ITS in Sigmodon, we gather data from C-bands, silver nitrate staining, G-bands, and chromosomal paint data from previous published studies. We did find some correlation with ITS and heterochromatin, euchromatic chromosomal rearrangements, and nucleolar organizing regions. No one type of chromosomal structure explains all ITS in Sigmodon. Multiple explanations and mechanisms for movement of intragenomic sequences are required to explain ITS in this genus. We rejected the hypothesis that age of a lineage correlates with the presence of ITS using divergence time estimate analyses. This multigene phylogeny places species with ITS (S. arizonae, S. fulviventer, S. hispidus, S. mascotensis, S. ochrognathus, and S. toltecus) in the clade with a species without ITS (S. hirsutus). Lineages with ITS (S. arizonae and S. mascotensis) arose independently from a lineage absent of ITS (S. hirsutus) around 0.67 to 0.83 Ma. The rearranged karyotypes of S. mascotensis and S. arizonae appear to be an independently derived autapomorphic characters, supporting a fast rate of chromosomal changes that vary among species.
|
2022-11-16T17:14:41.190Z
|
233,865,673 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/11795476211009234",
"MAG": null,
"PubMedCentral": "8064658"
},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://journals.sagepub.com/doi/pdf/10.1177/11795476211009234"
}
|
Hypoglycemic syndrome is a life-threatening condition that can lead to hypoglycemic coma and death. Surreptitious hypoglycemic syndrome is the deliberate use of insulin preparations or oral hypoglycemic drugs aimed to reduce blood glucose level. If human insulin is injected, high level of immunoreactive insulin (IRI) and low level of C-peptide at the moment of hypoglycemia are always detected. However, the fact of deliberate administration of insulin analogs is difficult to prove. In these cases if insulin kit test with low cross-reactivity with insulin analogs is used, the low levels of IRI and C-peptide will be suspected. Some experts suggest the presence of cross reactivity with analogs of insulin in a number of commercial kits, which makes it possible to detect cases of surreptitious hypoglycemia. We present a clinical case of a patient with surreptitious hypoglycemia due to the administration of insulin analogs and discuss the problems of its laboratory diagnosis.
|
2022-11-17T18:03:30.987Z
|
248,479,218 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3389/fphar.2022.851267",
"MAG": null,
"PubMedCentral": "9108379"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.frontiersin.org/articles/10.3389/fphar.2022.851267/pdf"
}
|
Tiaoganquzhi Decoction (TGQZD) is a traditional Chinese herbal formulation demonstrated to be a clinically effective treatment for nonalcoholic fatty liver disease (NAFLD), although details concerning its clinical mechanism are poor. This study aimed to explore the mechanism of TGQZD on improvement of inflammatory damage and dyslipidemia caused by NAFLD through the CGI-58/ROS/NLRP3 inflammasome pathway. In our research, the in vivo protective effects of TGQZD on HFD-induced liver injury in rats and in vitro using lipopolysaccharide (LPS)+palmitate (PA)-stimulated HepG-2 cells model. Histological changes were evaluated by hematoxylin-eosin and Oil Red O staining. Inflammatory cytokines and protein expression were analyzed by ELISA, Real time PCR and western blotting. Liver function, blood lipids, free fatty acids (FFA), and reactive oxygen species (ROS) were determined by biochemical detection. Our results indicated that TGQZD exhibited anti-inflammatory activity, reduced the severity of NAFLD and ameliorated the pathological changes. Further, TGQZD improved liver function and lipid metabolism in NAFLD rats. TGQZD lowered serum aspartate aminotransferase, alanine aminotransferase, triglyceride, and total cholesterol levels. TGQZD suppressed the formulation of FFA and ROS. It also reduced the expression and release of the inflammatory cytokine interleukin-1β by promoting CGI-58 expression and inhibiting the expression of FFA, TNF-α, and the NLRP3 inflammasome induced by ROS. TGQZD exhibited anti-inflammatory effects via the CGI-58, ROS and NLRP3 inflammasome pathway in vivo and in vitro, respectively. Our findings demonstrated that TGQZD is a useful and effective therapeutic agent for treating NAFLD via promotion of CGI-58 to inhibit the expression of ROS-induced NLRP3 inflammasome.
|
2022-12-11T18:34:39.644Z
|
119,196,039 |
{
"externalids": {
"ACL": null,
"ArXiv": "1106.2047",
"DOI": "10.1088/0004-637X/738/1/35",
"MAG": "2146642652",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Massive planetary cores (∼10 Earth masses) trigger rapid gas accretion to form gas giant planets such as Jupiter and Saturn. We investigate the core growth and the possibilities for cores to reach such a critical core mass. At the late stage, planetary cores grow through collisions with small planetesimals. Collisional fragmentation of planetesimals, which is induced by gravitational interaction with planetary cores, reduces the amount of planetesimals surrounding them, and thus the final core masses. Starting from small planetesimals that the fragmentation rapidly removes, less massive cores are formed. However, planetary cores acquire atmospheres that enlarge their collisional cross section before rapid gas accretion. Once planetary cores exceed about Mars mass, atmospheres significantly accelerate the growth of cores. We show that, taking into account the effects of fragmentation and atmosphere, initially large planetesimals enable formation of sufficiently massive cores. On the other hand, because the growth of cores is slow for large planetesimals, a massive disk is necessary for cores to grow enough within a disk lifetime. If the disk with 100 km sized initial planetesimals is 10 times as massive as the minimum mass solar nebula, planetary cores can exceed 10 Earth masses in the Jovian planet region (>5 AU).
|
2022-12-17T10:21:25.691Z
|
86,326,537 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1671/0272-4634(2007)27[881:AAFOTP]2.0.CO;2",
"MAG": "2168181194",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract For more than 100 years, most pterosaur workers have accepted the traditional reconstruction of the pteroid, articulated in the fovea of the preaxial carpal and directed medially along the anterior margin of a small propatagium in order to control it. A few workers have rejected the traditional reconstruction and advocated an alternative reconstruction with the pteroid directed anteriorly and controlling a large propatagium extending laterally past the wrist. Articulated specimens of a wide range of pterosaurs preserve a sesamoid associated with the tendon of M. flexorcarpi ulnaris in the fovea of the preaxial carpal. No specimen preserves the pteroid articulated in the fovea, and because the sesamoid articulated there, the pteroid could not. Therefore, both the traditional and alternative reconstructions, which are based on the assumption that the pteroid articulated in the fovea, are falsified. The preaxial carpal acted as a strut to increase the leverage of M. flexor carpi ulnaris for wrist extension. The pteroid articulated with the side of the carpal, was directed medially toward the shoulder, and could be extended and depressed to control the propatagium.
|
2022-12-20T09:59:14.576Z
|
149,263,073 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S0008413100025457",
"MAG": "2791147405",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The following notes are based on findings obtained in a pilot study of the speech of English-speaking residents of Montreal, which was carried out from 1957 to 1958. The data was obtained by circulating a questionnaire designed to elicit information on vocabulary, pronunciation, and grammar and syntax. In general, the choice of items for inclusion in this questionnaire was restricted to those which illustrate differences between British and American usage. In the vocabulary section, a further restriction was made in that no items pertaining exclusively to rural life were included. With respect to the selection of informants there were several deviations from the established methods of linguistic surveys. In most surveys it is usual to insist that informants belong to families which have been established in the area under investigation for several generations, and that they speak no other language but English.
|
2022-09-11T14:44:45.573Z
|
81,429,800 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.26442/2075-082X_13.1.15-21",
"MAG": "2884397436",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Aim. Compare the effectiveness of treatment with bisoprololum or sotalolum in patients with hypertensive disease (HD) and ventricular arrhythmias (VA) taking into account quantitative evaluation of the regulatory adaptive status (RAS).Materials and methods. 48 patients with HD of stages II-III and VA of grade I-IV based on the В.Lown grading system, II-III groups based on J.Bigger grading system took part in the research, they were randomized into two groups for treatment with bisoprololum (6.2±1.7 mg/day) or sotalolum (159.1±47.4 mg/day). As part of combination therapy, patients were administered lisinoprilum (12.8±4.2 mg/day and 13.7±4.5 mg/day), acetylsalicylic acid when required (93.1±19.0 and 95.0±16.2 mg/day), atorvastatinum (15.9±4.6 mg/day and 15.6±4.9 mg/day), respectively. Initially and 6 months after therapy, the following was done: quantitative assessment of RAS (by cardio-respiratory synchronism test), echocardiography, triplex scanning of brachiocephalic arteries, treadmill test, six-minute walk test, all-day monitoring of blood pressure and electrocardiogram, subjective assessment of quality of life.Results. Both drug regimens comparably improved structural and functional condition of the heart, increased exercise tolerance, controlled arterial hypertension, effectively suppressed ventricular arrhythmia, improved the quality of life. At the same time, the use of sotalolum decreased the RAS to a lesser degree than the use of bisoprololum.Conclusion. In patients with HD of stages II-III and VA the use of sotalolum as part of combination therapy may be preferable to bisoprololum due to its less negative impact on the RAS.
|
2022-12-02T11:44:09.658Z
|
143,031,764 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3818/JRP.2.2.2000.37",
"MAG": "1968880071",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper uses a recent process evaluation of Residential Substance Abuse Treatment (RSAT) block grant programs to illustrate the rationale for a systems approach to corrections-based treatment. First, the paper briefly discusses the history of treatment for the criminal justice offender and the origins of the “boundaryless” organization concept. Second, it presents results from a process evaluation of several jail-based drug treatment programs. These findings are then used to highlight the central components of “boundaryless” organizations and the respective policy and operational changes (e.g., assessment and treatment) needed to focus on improved offender outcomes, especially the client's completion of the treatment program. It provides a rationale for focusing on a systems approach as a means to use treatment as a crime prevention tool.
|
2022-12-14T03:06:18.302Z
|
203,387 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/26.780443",
"MAG": "2099166397",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
This article proposes a method to design a vector quantizer (VQ) for robust performance under noisy channel conditions. By re-optimizing the quantizer at progressively lower levels of assumed channel noise, the design is less susceptible to poor local optima. The method is applied to: (1) channel-optimized VQ design; and (2) index assignment for a source-optimized VQ. For both problems, we demonstrate substantial performance improvements over commonly used techniques.
|
2022-12-14T11:29:34.132Z
|
155,246,210 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2139/ssrn.2207771",
"MAG": "2293408023",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Using a new tax on fringe benefits initiated in India in 2005, this paper seeks evidence for the hypothesis that the difference in higher marginal tax rates on wages, relative to lower rates on fringe benefits, induces a reallocation of the total compensation package toward fringe benefits. Firm-level panel data on employee total compensation and wages across all industries is used to link their marginal tax rate on fringe benefits and choice of compensation. The key finding is that a tax on fringe benefits only affects the wage allocation of highly paid employees relative to employees lower on the pay scale. Using my most conservative estimate, I find that an increase in fringe-tax by 1 percentage point increases wages by one percent. Another major finding in this paper is that fringes are heterogeneous in nature and their provision can be for enhancing the productivity of an employee. In provision of such productivity enhancing fringes the firms observes a hierarchy among its employees.
|
2022-02-09T01:25:15.980Z
|
22,623,148 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1346-8138.2005.tb00722.x",
"MAG": "2013588763",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Psoriasis arthropathy (PsA) is a chronic inflammatory arthropathy characterized by the association of arthritis with psoriasis. In this study, clinical, laboratory and radiographic signs of 21 patients (12 males and 9 females), mean age of 42.2 years old, with PsA were assessed. The clinical forms defined by Moll and Wright revealed that oligoarticular pattern was most commonly observed in ten patients (47.6%), followed by polyarticular (5 patients), distal (3 patients), spondyloarthropathy (2 patients), and mutilans (1 patient). Positive rheumatoid factor was detected in three patients and antinuclear antibodies in eight patients, suggesting the involvement of immunological disregulation in this disorder. Twelve patients were onychopathic, of whom 11 showed distal interphalangeal (DIP) joint arthritis. Based on radiologic observation, spur formation of the calcaneus (1 patient) and destructive changes of the articulatio coxa (1 patient) were seen, in addition to the findings such as joint space narrowing, erosive changes, resorptive changes and ‘pencil‐in‐cup’ appearances. Non‐steroidal anti‐inflammatory drugs (NSAIDs) were used in all cases for the control of joint pain, solely or in combination with immunomodulatory drugs such as bucillamine, sulfasalazine, methotrexate, cyclosporin, etretinate, and mizoribine. However, some of those drugs were often ineffective for the joint pain, while effective for cutaneous psoriasis. Immunohistological studies of the biopsied synovial tissues from two patients showed increased expressions of CD45RO and HLA‐DR, suggesting that the vast majority of inflammatory cells are mature and activated T‐cells. Parallel immunostaining using the involved psoriatic skin from one of the patients also showed enhanced expression of CD45RO, but less expression of HLA‐DR as compared with its expression in the synovium. On the other hand, cutaneous leukocyte antigen (CLA) was abundantly detected in the inflammatory cells in the lesional skin, although less expressed in the synovium. These results are consistent with earlier observations suggesting a different subpopulation of inflammatory cells in the skin than the joint.
|
2022-10-18T19:06:51.779Z
|
122,670,852 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/TMAG.1983.1062425",
"MAG": "2086154706",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A calibration measurement for the temperature mapping system in use at CERN for superconducting accelerating cavities immersed in subcooled liquid helium is presented. It allows a study of cavity losses in a quantitative way by relating the temperature increase (ΔT) at the cavity outside wall to the power dissipated at the inside. The calibration set up simulates an isolated lossy region in a superconducting cavity. The influence of the bath temperature and the orientation of the heated surface have been investigated. ΔT is determined by the heat current density Q at the resistor location according to Δ T = α Q3/4. The proportionality constant α depends on the particular experimental conditions. The experimental results are compared with heat transfer calculations in subcooled helium. As an application typical loss mechanisms in superconducting cavities are described.
|
2022-12-13T09:58:55.176Z
|
206,370,621 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/pmic.201500038",
"MAG": "1994817306",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc4487608?pdf=render"
}
|
Efficient HIV transcription requires P‐TEFb, an essential co‐factor for Tat. In actively replicating cells, P‐TEFb is incorporated into the 7SK snRNP complex together with the repressor protein HEXIM1. Using an affinity purification‐tandem mass spectrometry approach to identify modification sites on HEXIM1 that regulate the sequestration of P‐TEFb by 7SK snRNP, we found that HEXIM1 can be phosphorylated on adjacent residues in a region immediately upstream of the coiled‐coil dimerization domain (Ser268, Thr270, Tyr271, and Tyr274). Phosphomimetic mutations of Tyr271 and Tyr274 disrupted the assembly of P‐TEFb and HEXIM1 into the 7SK snRNP complex. Although Y271E/Y274E did not adversely affect the nuclear localization pattern of HEXIM1, it induced the redistribution of the CDK9 subunit of P‐TEFb into the cytoplasm. By contrast, the Y271F/Y274F HEXIM1 mutant assembled normally with P‐TEFb within the 7SK snRNP complex but severely reduced proviral gene expression in T cells in response to activation signals and caused a severe growth defect of Jurkat T cells. Thus, Y271F/Y274F, which cannot be phosphorylated on these residues, appears to block the exchange of active P‐TEFb from the 7SK complex, thereby limiting the level of P‐TEFb below the threshold required to support transcription elongation of the HIV provirus and cellular genes.
|
2022-12-20T09:38:39.243Z
|
72,749,907 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.9734/BJMMR/2014/8379",
"MAG": "2056363536",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
data data Data Findings ABSTRACT Aims: This study investigated the role of graduated drivers licensing, implemented by the Traffic Police of Iran, on reducing the severity and incidence of road traffic injuries. Study Design: It was an evaluation of the effectiveness of intervention by looking at the data before and after intervention. Place and Duration of Study: Data on road traffic crashes and injuries from one year before, one year after and two years after the implementation of educated drivers licensing were obtained from Iran Traffic Police database in 2010. Methodology: In this study the effectiveness of provisional license intervention by looking at the data before and after intervention was evaluated. After data cleaning and stratification of traffic injuries and mortalities, the post-education records of drivers, in their early years of driving experience, were compared against their pre-education driving experience. holders of provisional B1 type driving license (p<0.001). Conclusion: Intervention is an effective way of reducing the number and severity of traffic injuries, particularly among the young and novice drivers are at a greater risk of RTIs. Such drivers can particularly benefit from graduated drivers licensing program which is proven to reduce the incidence and severity of road traffic injuries.
|
2022-12-30T00:13:01.688Z
|
122,774,115 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1063/1.1559437",
"MAG": "2088710910",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We report an avalanche photodiode with an undepleted p-type InGaAs absorption region and a thin InAlAs multiplication layer. The motivation for utilizing an undepleted absorption layer, which is similar to that in the unitraveling carrier photodiode, is to reduce the dark current. A dark current below 1 nA at a gain of 10 and a gain–bandwidth product of 160 GHz are demonstrated.
|
2022-12-31T20:09:36.453Z
|
143,768,733 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2298/gei0351097d",
"MAG": "1974187465",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://doi.org/10.2298/gei0351097d"
}
|
Investigation was carried out in north-east Serbia, in the region which is known for more freedom in male, female relations and marriages between minors. To prepare children for early marriage, the community takes care to introduce them to the world of adulthood through customs and to speed up their sexual maturity. Thus, on certain holidays, freedom in the behaviour of the young and the possibility of their getting to know each other more intimately was the accepted and publicly approved custom, although at the same time the strict rules of patriarchal morals, which prescribed the submissiveness in the behaviour of youth in daily life, were valid.
|
2022-02-09T07:19:29.241Z
|
164,210,027 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.24966/aas-8292/100004",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://doi.org/10.24966/aas-8292/100004"
}
|
Potato Tuber Moth (PTM), Phthorimaea operculella Zeller (Lepidoptera: Gelechiidae), is an important pest of potato. It is common that there is in most countries where potatoes are grown. The chemical insecticides are used to control PTM. Because of chemical adverse effect, there is need to find safe alternative to chemical insecticides. For this porpoise, the effect of two botanical insecticides and two new pesticides were investigated on PTM
|
2022-07-15T05:50:16.619Z
|
228,922,832 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1361-6463/abca60",
"MAG": "3100019219",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The high theoretical capacity of tin antimony (SnSb) alloys in lithium storage has gained a great deal of attention with respect to its application inbattery anodes. , The unstable structure of this alloy in terms of cycling is a huge limitation for this material; however, this can be effectively exterminated by doping with intermetallics. This work reports the improved electrochemical charcteristics of tin antimonide nanoparticles when nickel and iron are incorporated into the matrix. The as-prepared pristine and the Ni and Fe doped SnSb nanoparticles are analyzed in terms of their physiochemical properties via x-ray diffraction (with Rietveld refinement), Raman spectroscopy, Fourier transform infrared spectroscopy, scanning electron microscopy with energy dispersive x-ray analysis. The absence of any metal oxides in the SnSb: Fe, Ni system is confirmed by the x-ray photoelectron spectroscopy. The prepared alloy is subjected as an anode to cyclic voltammetry analysis for both aqueous and non-aqueous electrolytes, and their performance is satisfactory, exhibiting reversibility and improved specific capacity. Furthermore, the SnSb: Ni, Fe matrix exhibits a high electrical conductivity of 9.27 × 10−4 S cm−1 at room temperature, indicating improved anodic properties.
|
2022-07-31T09:10:31.045Z
|
5,753,871 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1136/gut.14.1.64",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://gut.bmj.com/content/gutjnl/14/1/64.full.pdf"
}
|
Two patients are presented in whom ischaemic colitis followed some years after abdomino-perineal excision of the rectum for carcinoma. The first patient was a young man without evidence of arterial disease and the second patient suffered from auricular fibrillation, thought to be due to ischaemic heart disease. Ligation of the inferior mesenteric artery in the operation of abdomino-perineal excision of the rectum may reduce the blood flow through the marginal artery of Drummond rendering the remaining colon more liable to ischaemic damage. Patients who pass bright blood through a colostomy following abdomino-perineal excision of the rectum for carcinoma may have ischaemic colitis rather than a recurrence of the neoplasm.
|
2022-10-07T00:33:39.072Z
|
93,965,005 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2116/ANALSCI.2.335",
"MAG": "1985062808",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A new synthetic multi-element reference material (SyRM) with polyacrylate-acrylamide gel matrix was prepared by co-polymerization reactions of homogeneous aqueous solutions of a mixture of acrylic acid and acrylamide containing known amounts of the elements of interest. The matrix elements are analogous to those of biological materials and their composition can simulate the biological samples to be analyzed. The excellent homogeneity and the quantitative retention of minor and trace elements were ascertained by using a radiotracer technique.
|
2022-10-14T00:38:52.385Z
|
32,541,387 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1128/iai.62.5.2129-2131.1994",
"MAG": "1947764520",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc186481?pdf=render"
}
|
Streptococcus gordonii DL1 (Challis) colonized the oral cavities of BALB/c mice that lacked streptococci, enterococci, and lactobacilli (LF mice) as members of an otherwise complex digestive tract microflora. Conventional mice, in comparison, were refractory to colonization by S. gordonii. Mice that harbored lactobacilli but were free of streptococci and enterococci (EF mice) had a lower incidence of colonization by S. gordonii than LF animals. The LF mouse system should be useful in the study of the molecular mechanisms that enable S. gordonii to inhabit the oral cavity.
|
2022-11-11T07:40:55.606Z
|
216,519,519 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/ijgi9040231",
"MAG": "3015714164",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2220-9964/9/4/231/pdf?version=1587431090"
}
|
Building pattern recognition is fundamental to a wide range of downstream applications, such as urban landscape evaluation, social analyses, and map generalization. Although many studies have been conducted, there is still a lack of satisfactory results, due to the imprecision of the relative direction model of any two adjacent buildings and the ineffective extraction methods. This study aims to provide an alternative for quantifying the direction and the spatial continuity of any two buildings on the basis of the Delaunay triangulation for the recognition of linear building patterns. First, constrained Delaunay triangulations (CDTs) are created for all buildings within each block and every two adjacent buildings. Then, the spatial continuity index (SCI), the direction index (DI), and other spatial relations (e.g., distance) of every two adjacent buildings are derived using the CDT. Finally, the building block is modelled as a graph based on derived matrices, and a graph segmentation approach is proposed to extract linear building patterns. In the segmentation process, the edges of the graph are removed first, according to the global thresholds of the SCI and distance, and are subsequently subdivided into subgraphs on direction rules. The proposed method is tested using three datasets. The experimental results suggest that the proposed method can recognize both collinear and curvilinear building patterns, given that the correctness values are all above 92% for the three study areas. The results also demonstrate that the novel SCI can effectively filter many insignificant neighbor relationships in the graph segmentation process. It is noteworthy that the proposed DI is capable of measuring building relative directions accurately and works efficiently in linear building pattern extraction.
|
2022-11-25T01:19:59.135Z
|
10,805,795 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1108/EL-04-2012-0037",
"MAG": "1486784541",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Purpose – The purpose of this study was to survey the level of readiness of three universities in Nigeria towards managing their digital records by assessing the e-records frameworks, infrastructures, and structural facilities that are available. Design/methodology/approach – The population of the study was 30 staff of the Registry Department in three Nigerian universities. Questionnaires, oral interviews, and check list were used during data collection. Data were analyzed using frequency tables, simple percentages, and bar charts. Findings – The paper found that universities in Nigeria are not ready to manage electronic records due to weak legislative and organizational frameworks. The paper recommends creation of awareness about e-records management, training of records personnel, adoption of hybrid records management and periodic auditing, provision of sustainable framework and infrastructure, among other things in Nigerian universities. Research limitations/implications – This study was carried out on...
|
2022-12-16T21:27:23.302Z
|
182,668,475 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/ACSSUSCHEMENG.9B01699",
"MAG": "2945866781",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Good design and fabrication of low-cost and efficient bifunctional electrocatalysts for both oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) are pivotal for rechargeable metal–a...
|
2022-12-18T23:49:10.761Z
|
55,418,337 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/0029-5515/54/2/023007",
"MAG": "2291882050",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
A comparison of the L–H power threshold (Pthr) in JET with all carbon, JET-C, and beryllium/tungsten wall (the ITER-like choice), JET-ILW, has been carried out in experiments with slow input power ramps and matched plasma shapes, divertor configuration and IP/BT pairs. The low density dependence of the L–H power threshold, namely an increase below a minimum density ne,min, which was first observed in JET with the MkII-GB divertor and C wall and subsequently not observed with the current MkII-HD geometry, is observed again with JET-ILW. At plasma densities above ne,min, Pthr is reduced by ∼30%, and by ∼40% when the radiation from the bulk plasma is subtracted (Psep), with JET-ILW compared to JET-C. At the L–H transition the electron temperature at the edge, where the pedestal later develops, is also lower with JET-ILW, for a given edge density. With JET-ILW the minimum density is found to increase roughly linearly with magnetic field, , while the power threshold at the minimum density scales as . The H-mode power threshold in JET-ILW is found to be sensitive both to variations in main plasma shape (Psep decreases with increasing lower triangularity and increases with upper triangularity) and in divertor configuration. When the data are recast in terms of Psep and Zeff or subdivertor neutral pressure a linear correlation is found, pointing to a possible role of Zeff and/or subdivertor neutral pressure in the L–H transition physics. Depending on the chosen divertor configuration, Pthr can be up to a factor of two lower than the ITPA scaling law for densities above ne,min. A shallow edge radial electric field well is observed at the L–H transition. The edge impurity ion poloidal velocity remains low, close to its L-mode values, ⩽5 km s−1 ± 2–3 km s−1, at the L–H transition and throughout the H-mode phase, with no measureable increase within the experimental uncertainties. The edge toroidal rotation profile does not contribute to the depth of the negative Er well and thus may not be correlated with the formation of the edge transport barrier in JET.
|
2022-12-28T18:19:48.724Z
|
129,382,793 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3997/2214-4609.20130588",
"MAG": "2008664096",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The recently completed Congo regional seismic survey shows regional scale features in high detail. Individual channel systems have been recognized and exploited but now the regional scale extent of these systems can be clearly visualized. The hydrocarbon bearing formations of the Congo Basin were formed by the rifting of the African and South American plates during the Late Jurassic. Four distinct phases of deposition and deformation are recognized in the Congo Basin; Pre-Rift, Syn-Rift, Post-Rift deposition, and Salt Tectonic deformation and while petroleum systems are found in all phases this paper focuses on the Upper Miocene sequence comprising deeper marine turbidite systems with sediment sourced via the Congo River. Extractions of amplitude anomalies within different time intervals show the details of multiple “meander-form” channel systems traversing the deep basin and terminating in fan shaped topography. These channels systems are 1 to 2km wide and trend generally from SE to NW. The source of the sediments carried in the channels is the Congo River Delta. Viewed regionally these features may be interpreted to provide information on paleocurrent direction, flow changes over time as well as displacement of channel systems due to offset by faulting and salt domes.
|
2022-02-09T14:46:17.013Z
|
225,417,595 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/23273798.2020.1797839",
"MAG": "3045429522",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
ABSTRACT Events unfold over time, i.e. they have a beginning and endpoint. Previous studies have illustrated the importance of endpoints for event perception and memory. However, this work has only discussed events with a self-evident endpoint, and the internal temporal structure of events has not received much attention. In this study, we hypothesise that event cognition computes boundedness, an abstract feature of the internal temporal structure of events. We further hypothesise that sensitivity to boundedness affects how individual temporal slices of events (such as event midpoints or endpoints) are processed and integrated into a coherent event representation. The results of three experiments confirm these hypotheses. In Experiment 1, viewers identified the class of bounded (non-homogeneous, culminating) and unbounded (homogeneous, non-culminating) events in a categorisation task. In Experiments 2 and 3, viewers reacted differently to temporal disruptions in bounded versus unbounded events. We conclude that boundedness shapes how events are temporally processed.
|
2022-09-24T15:56:18.434Z
|
5,704,944 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/SICE.2006.315462",
"MAG": "2062688231",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper describes localization and error correction of a mobile robot with a visual device which we have developed. The device can track floor image with natural texture and estimate the motion of a camera mounted in the robot. The robot is localized and controlled in real time according to information of position and direction estimated by the device. As a benefit of this method, accumulated errors of position and direction for a section in a path can be eliminated by finding an original floor image memorized at each target point where the robot reaches in the whole running. The robots have run a closed path repeatedly without a digression of the track by correcting the accumulated error. The method has a feature that double roles of both internal and external sensor are realized by a single image sensor
|
2022-12-12T04:49:41.663Z
|
234,436,217 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.9771/AA.V0I62.42892",
"MAG": "3129078595",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Resenha de: GONCALVES, Guilherme Leite; COSTA, Sergio. Um porto no capitalismo global: desvendando a acumulacao entrelacada no Rio de Janeiro . Sao Paulo: Boitempo, 2020. 152p.
|
2022-12-16T15:50:15.305Z
|
73,080,466 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4081/HLS.2015.4471",
"MAG": "2101688275",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
District health systems (DHS) are central to the global efforts to improve health outcomes but many remain ineffective. In many lowresource settings, despite the generally weak DHS there is evidence that some districts consistently perform well against the odds, and this is often attributed to the calibre of managers leading such districts and their management and leadership (M&L) skills. This paper examines the M&L practices of district health managers in high and low performing districts in Indonesia in an attempt to understand whether the differences in the performance of DHS can be explained, at least in part, by the differences in the performance of their health managers. We employed a mixed methods case study design focusing on two purposefully selected districts. Data were collected in 2011 using questionnaires and in-depth interviews. The preliminary results suggest that M&L practices of managers in the high and low performing districts are similar and provide little explanation for the differences in the performance of the two DHS. Contextual and health system factors offered a much better explanation for the variations in DHS performance.
|
2022-12-18T05:57:56.136Z
|
41,952 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/np400964w",
"MAG": "2326714760",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The leaves of Ageratina cylindrica afforded a thymol derivative that was characterized by physical and spectroscopical methods as (8S)-8,9-epoxy-6-hydroxy-l0-benzoyloxy-7-oxothymol isobutyrate (1). The absolute configuration of 1 was established as 8S by vibrational circular dichroism spectroscopy in combination with density functional theory calculations and by evaluation of the Flack and Hooft X-ray parameters. Compound 1 showed weak antiprotozoal activity against Entamoeba histolytica and Giardia lamblia trophozoites and a high inhibitory effect on hyperpropulsive movement of the small intestine in rats.
|
2022-12-18T21:32:58.377Z
|
77,434,203 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2298/VSP0401035J",
"MAG": "2422006105",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Background. Technetium-99m (99mTc) tetrofosmin scintigraphy is a new imaging method for the diagnosis of various malignancies, such as lung, thyroid, and most frequently breast neoplasms. The aim of this study was to evaluate the diagnostic reliability of 99mTc-Tetrofosmin breast scintigraphy in the detection of malignant breast disease. Methods. 99mTc -Tetrofosmin scintimammography (SMM) was performed in 28 patients with 30 breast lesions suspicious for malignancy. Standard mammography (MM) was also done. After surgery, the results of SMM and MM were compared to definitive histopathological findings as the "gold standard". After intravenous injection of radiotracer, SMM was performed in prone and supine views of the thorax, using large field-of-view Gamma camera. Results. The results of SMM were interpreted visually and semiquantitatively, and evaluated as positive or negative. Sensitivity, specificity and accuracy, positive (PPV) and negative predictive value (NPV) were obtained in relation to histopathology. After comparing the results of SMM and MM, SMM was proved more sensitive (95% for SMM vs. 80% for MM), while the specificity of both methods was similar. Conclusion. The results of this study indicate that the contribution of SMM as a nuclear medicine procedure has its place in the diagnostic protocol for patients suspected of malignant breast cancer.
|
2022-04-22T05:00:15.755Z
|
208,361,597 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/140349487600400103",
"MAG": "1716010684",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Hospital treatment of addicts arrested for intoxication in Finland. Niemi, T. (Dept. of Public Health Sciences, Univ. of Helsinki, Finland). In the present study the treatment of addicts as performed by the Finnish police was investigated. The intention was to evaluate how the treatment procedure functioned in meeting the need for medical care and safety of the addict. The series was collected from the police district of Helsinki, the Finnish capital, and comprised all addicts arrested and transported to hospital during 1969. The series totalled 859 cases, which is about 2% of all addicts arrested in Helsinki during 1969. The reasons for transportation to hospital were: external injuries (60%) and the addict's complaints of an injury or illness (17%). Of all subjects, 44 were admitted to a hospital ward and of these, 2 died later on the ward. Furthermore, 7 addicts had died at the police station, on the way to hospital, or at the out-patients' department. Thus the number of deaths totalled 9. On investigating the cases of death in detail it was found that omission of or delay in the transport to hospital may have been of decisive influence on the addict's death in 4 cases. It was estimated that, had the police not transported any of the addicts to hospital, the number of deaths would have been about 20. When the cost of hospital treatment and transport to hospital is used as an evaluation factor the effort of the activity covered by the present study is 98500 Fmk (U.S. 23 200). The output is the number of lives saved, i.e. 11. The efficiency of the activity is thus the saving of one life at the cost of about 9 000 Fmk (about 2 100 U.S.). The social characteristics of the addict were not found to have had a decisive bearing on the question of transportation to hospital. Differences between the various points of activity were observed in the relative numbers of the addicts arrested and transported to hospital.
|
2022-07-10T03:59:52.641Z
|
250,865,112 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/0256-307X/18/2/303",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The quantum fluctuations of the charge and current in a non-dissipative mesoscopic circuit with coupled inductors and capacitors are studied for the squeezed vacuum state. The influence of the phase angle upon the quantum fluctuations is discussed in particular. Our results indicate that when the circuit parameters remain constant and the phases θ of the two circuits are equal, the squeezing of the charge or its conjugate variable increases. When the difference of the two phases equals π, the squeezing will deteriorate. Therefore, if we want to decrease the quantum noise, we should not only control the amplitude r, but also control the phase θ carefully.
|
2022-07-31T01:49:41.204Z
|
251,685,138 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/agronomy12081937",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2073-4395/12/8/1937/pdf?version=1661392538"
}
|
Automated agricultural operations must be planned and organized to reduce risk and failure potential while optimizing productivity and efficiency. However, the diversity of natural outdoor environments and the varied data types and volumes required to represent an agricultural setting comprise critical challenges for the deployment of fully automated agricultural operations. In this regard, this study develops an integrated system for enabling an unmanned aerial vehicle (UAV) supported route planning system for unmanned ground vehicles (UGVs) in the semi-structured environment of orchards. The research focus is on the underpinning planning system components (i.e., world representation or map generation or perception and path planning). In particular, the system comprises a digital platform that receives as input a geotagged depiction of an orchard, which is obtained by a UAV. The pre-processed data define the agri-field’s tracks that are transformed into a grid-based map capturing accessible areas. The grid map is then used to generate a topological path planning solution. Subsequently, the solution is translated into a sequence of coordinates that define the calculated optimal path for the UGV to traverse. The applicability of the developed system was validated in routing scenarios in a walnuts’ orchard using a UGV. The contribution of the proposed system entails noise reduction techniques for the accurate representation of a semi-deterministic agricultural environment for enabling accuracy in the route planning of utilized automated machinery
|
2022-09-02T05:43:03.346Z
|
145,204,236 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/15427609.2005.9683345",
"MAG": "2089585612",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Many aging changes in the brain are separate from clinical disease and show evidence of adaptive compensation. The many levels of compensation are illustrated with age-related changes in dopamine neurotransmitter systems, myelination, gross structure, processing speed, and performance on neuropsychological and psychometric tests in middle and older ages. Major declines in very low-level processes that are not simultaneously paralleled by performance declines may indicate compensatory mechanisms that mask prodromal dementia. These patterns of change follow a model of biologically (genetically) programmed adaptive responses to aging in brain cells. Moreover, adaptive mechanisms also interact with the individual's environment, as suggested by the role of socioeconomic status and childhood experience in risk of cognitive impairment in old age. These findings support evolutionary mechanisms of natural selection along with extensive social support in brain aging that may be unique to humans.
|
2022-09-07T05:13:39.632Z
|
229,240,911 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1039/d0ra09067k",
"MAG": "3096937053",
"PubMedCentral": "9057476"
},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://pubs.rsc.org/en/content/articlepdf/2020/ra/d0ra09067k"
}
|
Using an open-cage C60 derivative possessing an orifice designed on the basis of computational studies, we have experimentally demonstrated the quantitative encapsulation of H2O as well as effective conversion into H2O@C60 in an overall yield remarkably higher than the previously reported methods by ca. 2–5 times.
|
2022-10-14T01:22:04.858Z
|
96,918,170 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/00222338508056616",
"MAG": "2049732323",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract Cationic polymerizations of β-propriolactone (Prop), ∊-caprolactone (Capr), and glycolide (Glyc) were initiated by various alkylsulfonates, such as methyl fluorosulfate, ethyl fluorosulfate, methyl trifluoromethanesulfonate (triflate), methyl methanesulfonate, methyl p-nitrobenzene sulfonate, γ-propane sultone, and δ-butane sultone. Systematic variation of reaction time and temperature revealed that only methyl fluorosulfate and methyl triflate can give high yields, yet the temperature must be kept in a narrow range (50 ± 10°C). Due to the living character of the cationic endgroups, high temperatures may cause rapid degradation of the initially formed polylactones. However, at appropriate temperatures, the living chain ends permit the synthesis of block copolyesters. The sequences of the two-block copolyesters built up of Prop and Glyc or Capr and Glyc units were characterized by means of 13C-NMR spectra and compared to random copolylactones. The DSC curves of the two-block copolyesters display t...
|
2022-10-30T16:09:55.977Z
|
84,815,943 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1439-0310.1997.TB00159.X",
"MAG": "2035626207",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Scent counter-marking, in which one individual deposits scent in close proximity to the scent of another individual, is a widespread but poorly understood aspect of olfactory communication. Recent work with golden hamsters suggests that animals may have specially evolved mechanisms for determining which individual has marked most recently, and this work emphasizes the need for studies with other species. In Experiment 1 it was shown for the first time that male meadow voles, Microtus pennsylvanicus, scent mark with urine and anogenital scents and probably also counter-mark with these scents. Female meadow voles, after investigation of an area marked by two males, preferred the whole-body odours of the male that had marked the arena most recently (Experiment 2). After females investigated a male's home cage that had just been marked by another male, they again preferred the whole-body odours of the male that had marked in the cage most recently (Experiment 3). These results demonstrate that female voles, like male hamsters, can distinguish the top or most recent individual's scent from the bottom or older scent in places marked by two males, and further indicate that female voles may prefer the individual that deposited the top scent. Taken together, the results suggest that counter-marking by male voles may be a type of competitive advertising and that females may base mate-choice decisions on information from the pattern of such counter-marks.
|
2022-12-02T16:49:57.420Z
|
206,386,993 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1108/14654659910280910",
"MAG": "1985107589",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Companies needing to establish competitive advantage must ensure their products are brought to market quickly, with the quality features sought by potential customers. Concurrent Engineering techniques can reduce time scales, but quality issues are more difficult, as customers’ needs are not readily available to the project team throughout the design process, so design effort may focus on satisfying a functional specification, imperfectly translated from customer requirements, rather than on satisfying the real customer needs as perceived in the market. The research reported here demonstrates how a Concurrent Engineering environment and Quality Function Deployment techniques can be brought together to provide an extended design team with valuable, shared information throughout the design process.
|
2022-12-13T01:02:45.657Z
|
36,124,647 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1086/598629",
"MAG": "67423274",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://academic.oup.com/cid/article-pdf/29/3/536/876406/29-3-536.pdf"
}
|
The course of pneumonia caused by pyogenic bacteria and Pneumocystis carinii was examined in a multicity cohort study of HIV infection. The median duration of survival among 150 individuals following initial bacterial pneumonia was 24 months, compared with 37 months among 299 human immunodeficiency virus (HIV)-infected control subjects matched by study site and CD4 lymphocyte count (P<.001). For 152 subjects with P. carinii pneumonia, median survival was 23 months, compared with 30 months for 280 matched control subjects (P = .002). Median durations of survival associated with the two types of pneumonia differed by only 47 days, despite a higher median CD4 lymphocyte count associated with bacterial pneumonia. These results suggest that both P. carinii pneumonia and bacterial pneumonia are associated with a significantly worse subsequent HIV disease course. The similarity of prognosis after one episode of bacterial pneumonia vs. an AIDS-defining opportunistic infection and the proportion of cases occurring in association with a CD4 lymphocyte count of >200 suggest that measures to prevent bacterial pneumonia should be emphasized.
|
2022-12-16T15:47:00.865Z
|
224,373,016 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3877/CMA.J.ISSN.2095-3216.2016.01.009",
"MAG": "3031711928",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In the last 20 years, the population of overweight and obesity has been growing rapidly. And obesity-related glomerulopathy (ORG), which can be directly induced by obesity, has received more and more attention. The pathogenesis of ORG is complex, including hemodynamic dysfunction, kidney hypoxia, insulin resistance, over-activation of sympathetic nerve, and so on, in which podocyte injury appears to play a central role. The typical renal histologic features of ORG consisted of simple obesity-associated glomerular hypertrophy, and obesity- associated focal segmental glomerulosclerosis. The most striking clinical characteristic of ORG is the existence of massive proteinuria with very low incidence of nephrotic syndrome. The treatment for ORG mainly aims at the proper control of the associated risk factors, such as weight control, ameliorating insulin resistance, inhibiting over-activation of RAAS, etc, in order to delay the deterioration of renal functions.
Key words:
Obesity-related glomerulopathy; Pathogenesis; Pathology; Clinical characteristics; Treatment
|
2022-01-27T09:59:30.601Z
|
87,289,184 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5264/EIYOGAKUZASHI.53.247",
"MAG": "2334932256",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Medium chain triglyceride (MCT) の添加量の違いが, シューの形状に及ぼす影響を, 常法と冷凍法について検討した。1) 焙焼による重量減少は, 常法ではMCT添加の影響は認められなかったが, 冷凍法ではMCT添加量90g, 105gのシューが有意に少なかった (p<0.01)。2) 水分比率は, 冷凍法に比べ常法では比率が高く, MCT添加量の増加とともに減少した。3) 常法・冷凍法とも, MCT添加により硬くなった。また, 体積は常法ではMCT添加量が増加するにつれて大きくなり, 冷凍法では減少した (p<0.05)。4) 常法では, 添加量の増加とともに底辺及び最大径に対する高さの比率は小さくなり, 冷凍法では, 底辺に対する高さの比率のみ小さくなった。5) シューの断面は, MCT添加量の増加とともに常法では横広がりとなり, 冷凍法では小さくなった。空洞の形成は, 常法よりも冷凍法が悪かった。6) 色については, MCT添加量の違いによる影響はほとんど認められなかったが, 冷凍法では明度, 白色度は常法より低値であった。7) MCT添加量が45g, 60g, 75g, 90gのシューについて順位法を用いて官能検査を行ったところ, 冷凍法のMCT45g添加シューが有意に好まれ, 90g添加シューは有意に好まれなかった。
|
2022-02-10T21:41:06.867Z
|
85,139,321 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1071/MU08019",
"MAG": "2070963250",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract The onset and duration of primary moult were investigated for adult Red-billed Queleas (Quelea quelea) in southern Africa. The duration of moult was shortest in Namibia (75 days), intermediate in Botswana (83 days) and longest in Gauteng Province (101 days) and the Eastern Cape (124 days), South Africa. The timing of the onset of moult was similar in Namibia and Botswana (21 and 31 May respectively), but considerably earlier in the Eastern Cape and Gauteng Province (6 and 23 April respectively). Completion of primary moult was well synchronised, ending in August in all sub-regions. Production of feather mass was uniform and speed of moult was controlled by the rate of growth of individual primaries. When moult was faster, fewer feathers grew simultaneously, possibly to reduce the aerodynamic effect of the wing-gap. Red-billed Queleas are thought to migrate relative to the movement of rain fronts, allowing possible multiple breeding events in one season. In southern Africa, Queleas are present throughout their range all year, and a proportion of the population moves short distances in apparently random directions. The large differences in timing and duration of moult in this study only support the short-distance ‘rainfall-migration’ model.
|
2022-02-10T23:40:07.030Z
|
209,461,268 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/09513590.2019.1706081",
"MAG": "2997027487",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract The aim of our study was to assess the value of serum AMH in prediction of metaphase II oocytes in poor responders. We performed a prospective cohort study included 206 poor responders candidate for ICSI using antagonist protocol. They were classified into 3 groups. Group I included 50 women with AMH < 0.3 ng/ml, group II included 85 women with AMH 0.3–0.7 ng/ml and group III included 71 women with AMH > 0.7–1.0 ng/ml. The primary outcome parameter was the number of MII oocytes. There was a highly significant difference between the study groups regarding E2 at triggering (481.41 ± 222.653, 648.17 ± 264.353 and 728.74 ± 305.412 respectively, number of oocyte retrieved (2.37 ± 1.178, 3.38 ± 1.622 and 3.80 ± 1.427 respectively), number of MII oocytes (1.66 ± 1.039, 2.35 ± 1.171 and 2.61 ± 1.080 respectively), number of fertilized oocytes (1.39 ± 0.919, 1.91 ± 0.983 and 2.21 ± 0.937 respectively), , total number of embryos (1.34 ± 0.938, 1.76 ± 0.956 and 2.09 ± 0.907 respectively), clinical pregnancy rates (4.9 vs. 7.7 and 19.7% respectively). We concluded that AMH is a good predictor for number of MII oocytes in poor responders undergoing ICSI.
|
2022-05-31T03:16:48.715Z
|
251,601,621 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.53550/eec.2022.v28i04s.037",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "http://www.envirobiotechjournals.com/EEC/augsuppl2022/EEC-36.pdf"
}
|
Gold (I) sulphide is the inorganic compound with the formula Au2 S. It is the principal sulphide of gold. Itdecomposes to gold metal and elemental sulphur, illustrating the nobility of gold. Recovering gold fromsulphide refractory gold ore has been an important guarantee for the sustainable development of goldindustry, while there are many challenges in the treatment of sulphide refractory gold ore, such asenvironmental pollution and low gold recovery. In this study we aimed at separating gold sulphide fromBanded Magnetite Quartzite (BMQ) of Goa. The BMQ sample wasdried, powdered, concentrated by panningmethod and subjected to magnetic separation using neodymium magnet and sieved into different fractionswith the sieve size of 250, 150, 106, 53 μm. Powdered sample was tested for presence of gold sulphide byICP-AES, SEM-EDX, CHNOS Analysis methods.
|
2022-08-19T19:01:56.417Z
|
197,277,130 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/10426500490427033",
"MAG": "2952693357",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
1-(2,4,6-Tri-tert-butylphenyl)-2-phosphaethyne (1) was allowed to react with 0.5 equiv of an alkyllithium and subsequently with an alcohol to afford a bulky 1,3-diphosphacyclobutene, and its structure and coordination properties on transition metals were investigated. On the other hand, 1 was allowed to react with an alkyllithium and iodomethane to form a stable biradical, 1,3-diphosphacyclobutane-2,4-diyl.
|
2022-09-07T04:09:39.495Z
|
67,782,807 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.18805/LR.V40I04.9007",
"MAG": "2751336228",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The effects of chloride salts (NaCl, MgCl2 and CaCl2) with the same electrical conductivity (EC) values on germination, emergence, seedling growth and Cl content of seedling in chickpea cultivars (Akcin 91, Aziziye, Gokce, Inci, Ioýk-05 and Yaoa-05) were investigated. The EC values of the chloride salts were adjusted to 4, 8 and 16 dS m-1 and the distilled water was served as control. Germination percentage, mean germination time, radicula and plumula lengths, fresh and dry radicula and plumula weight, chloride (Cl-) content of seedling in germination test, and seedling length, fresh and dry seedling weight in emergence test were measured. The results revealed that increasing salt doses caused a significant reduction in parameters of all cultivars. The dose of 16 dS m-1 from each salt was found to be lethal. Cl- content of seedling was increased from 0.05 ppm in control to 4.10 ppm in 16 dS m-1; resulting in decreasing germination, emergence and seedling growth. The cultivar Aziziye presented better performance and gave higher emergence rates in NaCl, while Ioýk-05 in CaCl2 and Gokce in MgCl2; indicating that there was a genotypic variation towards different salt sources. It was concluded that emergence and seedling growth were severely influenced by increasing salinity without changing germination and emergence was not possible at 16 dS m-1.
|
2022-09-21T15:58:25.157Z
|
138,092,728 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.17950/IJER/V3S4/423",
"MAG": "2340014185",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Nanotechnology is playing an increasingly important role in the development of biosensors. The sensitivity and performance of biosensors is being improved by using nanomaterials for their construction. The use of these nanomaterials has allowed the introduction of many new signal transduction technologies in biosensors. Because of their submicron dimensions, nanosensors,nanoprobes and other nano systems have allowed simple and rapid analyses in vivo. Portable instruments capable of analyzing multiple components are becoming available. This work reviews the status of the various nanostructure-based biosensors. Use of the self-assembly techniques and nano-electromechanical systems (NEMS) in biosensors is discussed.
|
2022-09-21T19:00:17.418Z
|
113,651,516 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/BAPI.201610019",
"MAG": "2478183009",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Energiesparendes Bauen erfordert zusätzlich zu einem hohen Wärmeschutz der Gebäude eine hohe Luftdichtheit der Gebäudehülle. Leckagen in Außenbauteilen sind aus diesem Grund und aufgrund der Tatsache, dass sie Ursache für feuchtebedingte Bauschäden sein können, zu vermeiden bzw. zu beheben. Zur Detektion von Leckagen können Thermografiebilder verwendet werden, die bisher jedoch nur eine lokale Ortung und keine Spezifikation des Energieverlusts durch die Leckage erlauben. Ziel der hier vorgestellten Analyse war es, das Potenzial der Thermografie hinsichtlich eines einfachen, schnellen und präzisen Verfahrens zur quantitativen Bestimmung des Energieverlusts infolge der Luftströmung durch eine Leckage abzuschätzen. Dazu wurde ein Versuchsstand entwickelt und experimentelle Untersuchungen wurden durchgeführt. Diese wurden mit numerischen Strömungssimulationen verglichen, wobei eine sehr gute Übereinstimmung zwischen Experiment und Simulation festgestellt wurde. Darüber hinaus konnte gezeigt werden, dass das Thermografiebild hoch sensitiv ist bezüglich der Strömungsgeschwindigkeit und der bauphysikalischen Kenngrößen des Baustoffs, der die Leckage besitzt. Dies zeigt, dass großes Potenzial darin besteht, aus dem Thermografiebild einer durchströmten Leckage Rückschlüsse auf den Energieverlust durch die Leckage ziehen zu können.
|
2022-03-31T23:54:44.835Z
|
144,811,059 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/014616727600200416",
"MAG": "2054089845",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In a brief discussion of some of the issues concerning the nature of social psychology which have been raised in recent articles by Gergen, Schlenker, Manis, and Thorngate, it is argued that there is a view about the nature of social psychology which takes advantage of and to some extent reconciles both Gergen's arguments for social psychology as history and Schlenker's argu ments for social psychology as science.
|
2022-07-31T04:08:52.260Z
|
54,732,118 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1155/2012/640568",
"MAG": "2106271003",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "http://downloads.hindawi.com/journals/aaa/2012/640568.pdf"
}
|
The generalized practical synchronization (GPS) of uncertain Duffing-Holmes chaotic systems with parameter mismatching, unknown external excitation, plant uncertainties, and uncertain deadzone nonlinearities is investigated. Based on the composite control approach, a tracking control is derived to realize the GPS for the uncertain Duffing-Holmes chaotic systems with parameter mismatching, unknown external excitation, plant uncertainties, and uncertain deadzone nonlinearities. Besides, the guaranteed exponential decay rate, convergence radius, and desired scaling factor can be prespecified. Finally, numerical simulations are provided to illustrate the feasibility and effectiveness of the proposed GPS scheme.
|
2022-09-01T07:17:46.347Z
|
213,959,218 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21769/bioprotoc.3506",
"MAG": "3004688878",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://bio-protocol.org/pdf/Bio-protocol3506.pdf"
}
|
Chlamydia trachomatis is an obligate human pathogen. It infects the genital tract of humans ascending into the fallopian tube, exacerbated by chronic pelvic pain, pelvic inflammatory disease, and fallopian tube scaring resulting in infertility and other malignancies. The major hurdle in controlling chlamydial spread is that the infection remains asymptomatic, thus leading to chronic, recurrent and persistent infections, with no vaccines developed so far. Being a human pathogen, we do not have an in vivo model of C. trachomatis infection. C. trachomatis do not cause ascending infections and fallopian tube pathology in the mouse urogenital tract when infected vaginally. To overcome this hurdle trans cervical method of infection must be adapted. In this protocol the method of establishing trans-cervical Chlamydial infection with the procedure to determine the bacterial load is detailed. This method will facilitate to deliver the bacteria past the cervix establishing an ascending infection into the uterine horns reciprocating human fallopian tube infections.
|
2022-09-02T04:50:48.237Z
|
249,939,335 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3389/fpsyg.2022.886619",
"MAG": null,
"PubMedCentral": "9253821"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.frontiersin.org/articles/10.3389/fpsyg.2022.886619/pdf"
}
|
Cognitive neuropsychology seeks a potential alignment between structural and functional brain features to explain physiological or pathological processes, such as Alzheimer’s disease (AD). Several structural and functional brain changes occurring during the disease, including cognitive impairment, are found at the end of the patient’s life, but we need to know more about what happens before its onset. In order to do that, we need earlier biomarkers at preclinical stages, defined by those biomarkers, to prevent the cognitive impairment. In this minireview, we have tried to describe the structural and functional changes found at different stages during AD, focusing on those features taking place before clinical diagnosis.
|
2022-09-16T05:24:20.640Z
|
167,911,106 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5367/ihe.2013.0146",
"MAG": "2058906839",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In a rapidly changing world of knowledge exchange, innovation and technological advancements, entrepreneurship continues to fuel economic growth in both developed and developing countries. In the developed world, an increased influx of graduate entrepreneurs sustains economic growth whilst, in contrast, developing countries continue to suffer from a dearth of entrepreneurial learning mechanisms. To remedy this situation in Ghana a collaborative and interdisciplinary venture, involving the Business School of the Kwame Nkrumah University of Science and Technology and an international panel of experts, has developed the Kite Vision Actualization Laboratory (KVAL). The raison d'être of the KVAL is to support and nurture talent, develop and implement business solutions and innovations, encourage the development of entrepreneurial undergraduate and postgraduate programmes and stimulate graduate business start-ups. The KVAL integrates four development stages of entrepreneurial learning: knowledge transfer and exchange; innovations and inventions; technology and enterprise development; and panel review, assessment and final approval protocols. The innovative KVAL framework mirrors demand-led transformation and self-actualization processes that represent a departure from traditional offerings in entrepreneurship education.
|
2022-02-08T18:42:45.178Z
|
31,786,327 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/03014460500097443",
"MAG": "1992614009",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Background: Anthropometric variation can be fruitfully utilized to investigate microevolutionary processes. Anthropometric variations in the Indian subcontinent based on stature and three indices (Cephalic Index, Nasal Index, and Total Facial Index) are highly variable and discriminative among populations across geographical regions. Aims: Anthropometric variation in stature, Cephalic Index (CI), Nasal Index (NI) and Total Facial Index (TFI) were investigated with respect to ethnic, linguistic, geographical and climatic affiliation, across the Indian subcontinent. Subjects and methods: Published data on anthropometric variations of 531 populations from the Indian subcontinent were analysed using discriminant analysis and spatial autocorrelation analysis. Results: Discriminant analysis of the four anthropometric variables shows that stature and NI are good discriminators for populations of different languages. Stature, NI and CI discriminate well among populations of diverse ethnic origin and climatic conditions in different regions. TFI is not a good discriminator for populations of diverse ethnic, linguistic and climatic attributes. Spatial autocorrelation analysis showed significant departure from randomness, suggesting geographic structuring. The Moran's I estimate is positive and statistically significant for the four variables at low distances but exhibits significant negative association at higher values. Conclusion: The results suggest geographical clines for the four anthropometric variables and indicate the influence of population structure on the studied variables.
|
2022-12-23T16:30:08.283Z
|
164,813,374 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5325/weslmethstud.7.1.0121",
"MAG": "2755827244",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This article contains annotated transcriptions of several previously unknown letters between John Wesley and Revd John Lewis of Holt, Wiltshire, in the mid-1740s. Holt's letters articulate the concerns of a typical Anglican parish priest about irregular ecclesial practices and some doctrinal emphases of the Methodist revival. Wesley's responses contain his most frank (or pessimistic) evaluation of Anglican clergy—that two thirds of those he has known are ‘blind leaders of the blind, dumb dogs that cannot bark, priests of Baal rather than God’. Together the letters provide an instructive window into the reception of early Methodism.
|
2022-01-27T09:50:54.413Z
|
191,415,676 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21176/PROTAN.V2I8.155",
"MAG": "1557224177",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Fotosintesis berperan memproduksi hasil tanaman yang diperoleh dari energi cahaya matahari. Efisiensi fotosintesis dapat dilakukan dengan modifikasi lingkungan dengan penggunaan mulsa dan ajir. Penelitian ini betujuan untuk mengetahui jenis mulsa yang tepat dan penggunaan ajir pada budidaya kentang dalam mening-katkan produksi umbi kentang varietas Gra-nola. Penelitian dilaksanakan pada bulan September 2013 sampai dengan bulan Desember 2013, di Dusun Junggo, Desa Tulungrejo, Kec. Bumiaji, Kota Batu. Metode penelitian yang digunakan adalah Ran-cangan Acak Kelompok (RAK) dengan 8 perlakuan yang diulang 4 kali. Penggunaan ajir dan mulsa pada tanaman kentang ( Solanum tuberosum L.) memberikan pe-ngaruh pada pertumbuhan tanaman dan hasil produksi umbi kentang varietas Gra-nola. Hasil penelitian menunjukkan penggu-naan ajir dan mulsa plastik hitam perak menigkatkan bobot segar umbi panen 32,87 % lebih besar dibandingkan dengan perla-kuan tanpa ajir + mulsa plastik hitam perak, 64,62 % lebih besar ajir + tanpa mulsa dan 69,13 % lebih besar dibandingkan dengan perlakuan tanpa ajir dan tanpa mulsa. Peng-gunaan ajir dan mulsa plastik perak me-nigkatkan bobot segar umbi panen 19,04 % lebih besar dibandingkan dengan perlakuan tanpa ajir + mulsa plastik perak, 43,62 % le-bih besar ajir + tanpa mulsa dan 47,56 % lebih besar dibandingkan dengan perlakuan tanpa ajir dan tanpa mulsa. Kata kunci : Solanum tuberosum L, Varietas Granola, Ajir, Mulsa
|
2022-02-08T09:06:09.706Z
|
61,760,479 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5100/JJE.22.239",
"MAG": "2332452711",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
本研究は, 操舵角ゲインおよび操舵力 (復元力, 慣性力および乾性摩擦力) を変化する機能を有する操舵シミュレータの被験者を観察し, 操舵角ゲインおよび操舵力が操舵角制御に及ぼす影響を検討したものである. 被験者が追跡制御を行っているときの制御成績, 主観的評点および生体反応 (SPL, SPR, EMG) の評価を行った. その結果, 主として次の諸点が明らかになった.(1) 被験者は, 操舵角ゲインが大きい場合には精神的負担を受け, 逆にそれが小さい場合には筋的負担を受ける.(2) 操舵角ゲインが大きい場合, ある程度の復元力により制御成績が改善される.(3) わずかの慣性力またはわずかの乾性摩擦力により制御成績は向上する傾向がある.
|
2022-02-11T15:35:39.923Z
|
170,591,998 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/0040571X9209500103",
"MAG": "2332534326",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The question which I am ultimately trying to address in this article is: what does the Trinity have to do with human individuality? My question reflects the renewal of interest in trinitarian theology amongst systematic theologians in the West which followed their familiarization with the social conceptions of the Orthodox churches.' But why should the availability of social and relational frames of reference for the Trinity have proved so reinvigorating for systematics in the West? There are two reasons, I think. The first is that the social understanding of the Trinity seems to offer a way of taking conventional Christian doctrine seriously whilst avoiding the obscurity and mystification of metaphysical conceptions. The second is that it provides an immediate and obvious connection with theological anthropology, and hence with practical theology in general and with political theology in particular. For in using social terms to conceptualize the Trinity, one is bound to formulate a conception of
|
2022-09-12T02:19:48.094Z
|
1,919,386 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/APSEC.1996.566749",
"MAG": "1898730719",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Based on the capability maturity model (CMM), process improvement at OMRON, a Japanese microprocessor manufacturer, increased project predictability in three ways: accuracy, variability, and performance. The authors use the project visibility index (PVI) and other measurements to quantitatively demonstrate this. Qualitative analysis of how and why OMRON achieved higher project visibility and increases in the QCD (quality, cost, and delivery on time) factors are supported with data on review-effort ratios and productivity. They identify factors directly affected by high project visibility.
|
2022-09-13T06:48:28.870Z
|
253,194,152 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3897/bdj.10.e90103",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://bdj.pensoft.net/article/90103/download/pdf/"
}
|
Historical field data in ecology are exceedingly rare and, therefore, their preservation and publication is of high importance, especially as these data can function as a point of reference for present day biodiversity research. Therefore, we digitised a 65-year-old dataset on ground-dwelling beetles caught with pitfall traps in the coastal dune area "Meijendel", situated in the western part of the Netherlands.
The data presented in this paper has never been published in a systematic way before and has had a long journey from moment of capture to the current digitisation. From 1953 through to 1960, 100 pitfalls were active and catches were collected once a week. A total of 36,400 samples were aggregated with approximately 90,000 occurrences recorded. All captures were identified up to species level and counted and sex determined where possible. The database has been registered in the Global Biodiversity Information Facility (GBIF) and can be found under: https://www.gbif.org/dataset/9d02b439-aa5c-4c22-b1d9-d27fbde9e3ee.
|
2022-12-16T15:47:54.040Z
|
22,110,968 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1476-5381.1995.tb17217.x",
"MAG": "2058487112",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://bpspubs.onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1476-5381.1995.tb17217.x"
}
|
1 . We have shown earlier that pilocarpine strongly inhibits mouse and human liver coumarin 7‐hydroxylase activity of CYP 2A and pentoxyresorufin O‐deethylase activity of CYP 2B in vitro. Since pilocarpine, like coumarin, contains a lactone structure we have studied in more detail its inhibitory potency on mouse and human liver coumarin 7‐hydroxylation. 2 . Pilocarpine was a competitive inhibitor of coumarin 7‐hydroxlase in vitro both in mouse and human liver microsomes although it was not a substrate for CYP 2A5. Ki values were similar, 0.52 ± 0.22 μm in mice and 1.21 ±0.51 μm in human liver microsomes. 3 . Pilocarpine induced a type II difference spectrum in mouse, human and recombinant CYP 2A5 yeast cell microsomes, with Ka values of 3.7 ±1.6, 1.6 ±1.1 and 1.5 ±0.1 μm, respectively. 4 . Increase in pH of the incubation medium from pH 6 to 7.5 increased the potency of inhibition of coumarin 7‐hydroxylation by pilocarpine. 5 . Superimposition of pilocarpine and coumarin in such a way that their carbonyls, ring oxygens and the H‐7′ of coumarin and N‐3 of pilocarpine overlap yielded a common molecular volume of 82%. 6 . The results indicate that pilocarpine is a competitive inhibitor and has a high affinity for mouse CYP 2A5 and human CYP 2A6. In addition the immunotype nitrogen of pilocarpine is coordinated towards the haem iron in these P450s.
|
2022-12-19T03:09:06.923Z
|
26,583,382 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1056/NEJM197508282930906",
"MAG": "2040925731",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Copper bearing intrauterine devices have become the most reputable effective and safe IUDs available. The reaction between the copper and the body prevents fertilization. An infiltration of polymorphonuclear leukocytes occur in the uterine lumen as a result of the IUD. The daily released copper is equivalent to 1% of the copper taken orally by day. Alpha amylase activity is depressed; cyclic increase in glycogen synthetase is eliminated. Copper can inhibit enzyme activity even if cupric ions from the metal are at a low concentration. The effect of copper on the myometrium accounts for the lower initial expulsion rates for copper bearing devices. The uterus loses its ability to contract after prolonged exposure to copper. The chemical breakdown between cuprous oxide and saline produces a cuprous complex which yields cupric ion and free radicals. The inhibition of the implantation process of the copper may lead to an explanation. Metallic copper liquifies endometrial mucoids. Cupric ions increase the biosynthesis of certain prostaglandins. Prostaglandins may be another explanation of implantation inhibition. Further research on implantation is needed.
|
2022-12-19T20:12:46.230Z
|
2,220,080 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1115/1.1992528",
"MAG": "2137610248",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "http://www-mech.eng.cam.ac.uk/profiles/fleck/papers/190.pdf"
}
|
An experimental study has been conducted on the penetration of silicone rubbers and human skin in vivo by sharp-tipped and flat-bottomed cylindrical punches. A penetrometer was developed to measure the penetration of human skin in vivo, while a conventional screw-driven testing machine was used to penetrate the silicone rubbers. The experiments reveal that the penetration mechanism of a soft solid depends upon the punch tip geometry: a sharp tipped punch penetrates by the formation and wedging open of a mode I planar crack, while a flat-bottomed punch penetrates by the growth of a mode II ring crack. The planar crack advances with the punch, and friction along the flanks of the punch leads to a rising load versus displacement response. In contrast, the flat-bottomed punch penetrates by jerky crack advance and the load on the punch is unsteady. The average penetration pressure on the shank cross section of a flat-bottomed punch exceeds that for a sharp-tipped punch of the same diameter In addition, the penetration pressure decreases as the diameter of the sharp-tipped punch increases. These findings are in broad agreement with the predictions of Shergold and Fleck [Proc. R. Soc. London, Ser. A (in press)] who proposed models for the penetration of a soft solid by a sharp-tipped and flat-bottomed punch.
|
2022-12-28T23:01:48.468Z
|
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