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25,047,063
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/PESTSE.2016.7516439", "MAG": "2493969149", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This paper presents the design and implementation of sliding mode control law to the output voltage control of DC to DC buck converter. The robustness of the sliding mode controller is tested by changing the different circuit components and comparing the results with conventional linear controller. The result shows that the sliding mode controller performs better in the transient condition over a wide range of operation when compared with linear controller. Sliding mode controllers by using hysteresis modulation and pulse width modulation are implemented in MATLAB/simulink. The disadvantages of sliding mode controller by using hysteresis modulation is overcome by using pulse width modulation.
2022-12-10T16:20:18.082Z
127,826,741
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1079/9781845930981.0000", "MAG": "389525565", "PubMedCentral": null }, "license": null, "status": null, "url": null }
* Foreword, J C Gordon, former Dean and Emeritus Professor, Yale School of Forestry and Environmental Studies, President Interforest LLC * Introduction, K A Vogt, J M Honea, D J Vogt, R L Edmonds, T Patel-Weynand, R Sigurdardottir and M G Andreu * Historical Perceptions and Uses of Forests, K A Vogt and R I Gara, University of Washington, USA, J M Honea, USA, D J Vogt, T Patel-Weynand, A Fanzeres, Rio de Janeiro, Brazil, R Sigurdardottir, and P A Roads, Ohio, USA * Global Societies and Forest Legacies Creating Today's Forest Landscapes, K A Vogt, J M Honea, D J Vogt, R L Edmonds, R Sigurdardottir, T Patel-Weynand, D G Briggs, University of Washington, USA, and M G Andreu * Human Dimensions of Forests: Democratization and Globalization of Forests, K A Vogt, T Patel-Weynand, J M Honea, R I Gara, D J Vogt, R Sigurdardottir, A Fanzeres, M G Andreu * Ecology and Conservation of Forests, J M Honea and K A Vogt * Human and Natural Disturbances Impacting Forests, R L Edmonds, K A Vogt, T Patel-Weynand * Forests and the Carbon Cycle, D J Vogt, R Sigurdardottir, D Zabowski, University of Washington, USA, and T Patel-Weynand * Emerging Issues in Forests, K A Vogt, T Patel-Weynand, M G Andreu, G K Muller, National Wildlife Federation, USA, J M Honea, D J Vogt, R L Edmonds, and R Sigurdardottir * It's a Small World After All, D J Vogt, and P A Roads.
2022-12-07T16:59:30.086Z
203,449,322
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.4187/respcare.05304", "MAG": "2619334489", "PubMedCentral": null }, "license": null, "status": "BRONZE", "url": "http://rc.rcjournal.com/content/respcare/62/6/776.full.pdf" }
Pediatric lung transplant is a viable option for treatment of end-stage lung disease in children, with > 100 pediatric lung transplants reported to the Registry of the International Society of Heart and Lung Transplantation each year. Long-term success is limited by availability of donor organs, debilitation as a result of chronic disease, impaired mucus clearance resulting from both surgical and pharmacologic interventions, increased risk for infection resulting from immunosuppression, and most importantly late complications, such as chronic lung allograft dysfunction. Opportunities for investigation and innovation remain in all of these domains: (1) Ex vivo lung perfusion is a promising technology with the potential for increasing the lung donor pool, (2) evolving extracorporeal support strategies coupled with effective rehabilitation will effectively bridge critically ill patients to transplant, and most importantly, (3) research efforts intended to increase our understanding of the underlying mechanisms of chronic lung allograft dysfunction will ultimately lead to the development of effective therapies to prevent or treat the variety of chronic lung allograft dysfunction presentations.
2022-12-17T18:24:25.948Z
146,479,671
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1068/a4611", "MAG": "2167853503", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Stakeholders and citizens today are often invited to deliberate in controversial processes of scientific and technological decision making. Scholars in the field of science and technology studies (STS) have long supported these initiatives to transcend strong expert–lay divides. However, despite many such contributions, there is no agreement on how such broadened participation should be performed, either in theory or in practice. The theoretical ambition of this paper is to reformulate the opposing viewpoints of Michel Callon and Harry Collins on public participation in scientific and technological decision making. It is argued that they try to ‘heat up’ (Callon) or ‘cool down’ (Collins) the issues they study: that is, that they enact them differently. The performative outcomes of these two strategies for participation are analysed. The empirical ambition is to study recent developments in participatory approaches to radioactive waste management in Belgium and Sweden and the role of social science in connection with these. Due to public criticism of earlier top-down technocratic approaches, this field has played a significant role in enacting and supporting broadened participation. Moreover, while the waste programmes in Belgium and Sweden have both been internationally recognised as taking participation seriously, they have varied considerably in terms of participatory technologies and involvement of social science. A conclusion is that social science research has influenced how participatory engagements are organised in radioactive waste programmes, and thereby has become involved in processes of ‘heating up’ and ‘cooling down’. However, social scientists, as well as all actors, need to be more aware of their own preconceptions about the issue at stake—in terms of its being “hot” or “cold”—and the consequences of these enactments.
2022-12-19T00:50:53.876Z
137,642,010
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.4028/www.scientific.net/KEM.270-273.1038", "MAG": "1967331233", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This study was carried out to develop a sensor to detect weeds in paddy field. A machine vision system consisted of an optical band-pass filter equipped monochrome CCD camera and a frame grabber installed on a personal computer was selected for the purpose. Three optical filters of center wavelengths of 560, 680 and 800 [nm] with a bandwidth of 10 [nm] were tested before developing algorithms for the system. An algorithm for the vision system was developed using image processing procedures and pattern recognition techniques. Actual field images of weeds and rice were taken using the vision system at several growth stages of rice. Images of the plants (weeds and rice) were easily distinguished from wet soil background by the thresholding process. To discriminate between weeds and rice from the images of plants, a classifier using features based on pixel values and numbers of the plant images was developed. The minimum distance method of pattern recognition was applied to develop a classifier. Image processing algorithms to detect weed images was developed using the classifier. Performance of the machine vision system using the developed algorithms was tested with all the images taken. The test resulted that the developed system is favorable but requires more study for practical use.
2022-12-19T18:44:16.531Z
120,176,210
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1117/12.204690", "MAG": "1765648738", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Light-emitting diodes (LED5) based on organic semiconductors have received much attention recently due to their promise as cheap, novel light sources for electro-optical applications. Unlike conventional diodes, light emission from these organic LEDs is achieved by double injection of electrons from a low-work-function electrode and holes from a high-work-function electrode into the organic polymer light-emitting layer. By appropriately engineering the polymer backbone, emission of various visible colors has been demonstrated. Our work in this field has concentrated on organic block copolymers as the active light-emitting materials. We demonstrate that the use of copolymer systems leads to large enhancement of device performance.
2022-08-29T02:54:15.178Z
169,437,039
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.4312/LINGUISTICA.52.1.349-362", "MAG": "439017757", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The dual is a grammatical expression of number in some languages (e.g. Slovene, Sorbian or Modern Standard Arabic) that denotes two persons or objects. In modern Indo-European languages, the dual is an archaism and one that has been preserved only in a small number of Slavonic languages: in Slovene, Upper and Lower Sorbian and Cassubian; in other Indo-European languages the dual has been replaced by the plural. This paper will present this specific grammatical category as preserved to the present day in Standard Slovene, Colloquial Slovene and various Slovene dialects, and enable more precise comparisons and contrasts to be drawn with the dual in all three forms of the Slovene language.
2022-09-10T04:22:26.903Z
30,402,201
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1002/cncr.22810", "MAG": "2063556517", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This study summarizes long‐term outcomes from treatment of prostate cancer with increased risk of extracapsular cancer extension (ECE) using brachytherapy‐based treatment.
2022-12-09T13:29:22.881Z
94,462,517
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1021/CG200356X", "MAG": "1966192135", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The feasibility of the Depressurization of an Expanded Liquid Organic Solution (DELOS) method to process different active pharmaceutical ingredients (APIs) as finely divided powders with narrow particle size distribution, high crystallinity degree, high polymorphic purity, and free from residual solvent has been demonstrated. Cholesterol, acetylsalicylic acid (aspirin), naproxen, acetaminophen, and ibuprofen were chosen as model drugs. It has been demonstrated that the supersaturation ratio attained during crystallization from CO2-expanded solvents can be modulated through appropriate variations of process parameters  CO2 content and concentration of the initial solution. In view of the potential application that compressed fluidsbased technologies have in the pharmaceutical industry, a preliminary scalability study of the process in compliance with the constraints imposed by the Good Manufacturing Practices (GMP) specifications is presented herein
2022-12-15T03:34:35.292Z
27,028,464
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/fuzz-ieee.2012.6250780", "MAG": "1986428756", "PubMedCentral": null }, "license": "CC0", "status": "GREEN", "url": "https://zenodo.org/record/1268569/files/article.pdf" }
In this paper, we explored the use of features that represent body posture and movement for automatically detecting people's emotions in non-acted standing scenarios. We focused on four emotions that are often observed when people are playing video games: triumph, frustration, defeat, and concentration. The dataset consists of recordings of the rotation angles of the player's joints while playing Wii sports games. We applied various machine learning techniques and bagged them for prediction. When body pose and movement features are used we can reach an overall accuracy of 66.5% for differentiating between these four emotions. In contrast, when using the raw joint rotations, limb rotation movement, or posture features alone, we were only able to achieve accuracy rates of 59%, 61%, and 62% respectively. Our results suggest that features representing changes in body posture can yield improved classification rates over using static postures or joint information alone.
2022-12-17T07:09:31.119Z
255,285,599
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3390/electronics12010149", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
Cancer of the brain is most common in the elderly and young and can be fatal in both. Brain tumours can heal better if they are diagnosed and treated quickly. When it comes to processing medical images, the deep learning method is essential in aiding humans in diagnosing various diseases. Classifying brain tumours is an essential step that relies heavily on the doctor’s experience and training. A smart system for detecting and classifying these tumours is essential to aid in the non-invasive diagnosis of brain tumours using MRI (magnetic resonance imaging) images. This work presents a novel hybrid deep learning CNN-based structure to distinguish between three distinct types of human brain tumours through MRI scans. This paper proposes a method that employs a dual approach to classification using deep learning and CNN. The first approach combines the unsupervised classification of an SVM for pattern classification with a pre-trained CNN (i.e., SqueezeNet) for feature extraction. The second approach combines the supervised soft-max classifier with a finely tuned SqueezeNet. To evaluate the efficacy of the suggested method, MRI scans of the brain were used to analyse a total of 1937 images of glioma tumours, 926 images of meningioma tumours, 926 images of pituitary tumours, and 396 images of a normal brain. According to the experiment results, the finely tuned SqueezeNet model obtained an accuracy of 96.5%. However, when SqueezeNet was used as a feature extractor and an SVM classifier was applied, recognition accuracy increased to 98.7%.
2022-12-31T17:46:42.837Z
219,093,723
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.21608/ajs.2020.23708.1167", "MAG": "3019496966", "PubMedCentral": null }, "license": "CCBYNCSA", "status": "GOLD", "url": "https://ajs.journals.ekb.eg/article_83167_b134b6c09b0705181974ad7440d94545.pdf" }
إن الاتجاه حالیا فى معظم دول العالم سواء المتقدمة أو النامیة هو کیفیة الحصول على اکبر قدر ممکن من المکاسب فى ظل ما تملکه الدولة من موارد متاحه وطرق الإنتاج المستخدمة وکیفیة إدارة تلک الموارد فى ظل مناخ استثمارى یتوافق مع تلک المتغیرات ، ولا تستطیع أی دولة أن تعیش بمعزل عن سائر الدول الأخرى فی العالم سواء کانت تلک الدولة غنیة بالموارد ولها فائض فی الإنتاج و ترغب فی تصریفه أو کانت فی حاجة إلى الدول الأخرى فی الحصول على قدر کاف من سلعة ما تکفی احتیاجات سکانها . وعلى الرغم من الأهمیة التصدیریة الکبیرة لمحصول الموالح المصریة واحتلاله المرتبة الأولى فی قائمة الصادرات الزراعیة المصریة، واحتلال مصر المرتبة الثالثة عالمیا فی تصدیرها ، إلا أن صادراته قد اتسمت بالتذبذب وعدم الاستقرار خلال الفترة(2018-2001) وهو ما یؤدی الی تذبذب العائد من هذه الصادرات ، الأمر الذی یتطلب ضرورة الوقوف على محددات الطلب الخارجی على هذه الصادرات فی مختلف الأسواق العالمیة لتوفیر السبل اللازمة لتنمیة هذه الصادرات والنهوض بها والمحافظة على أسواقها الحالیة وفتح أسواق جدیدة لها وفی ضوء مشکلة الدراسة وفی محاولة للتعرف علی أهم المتغیرات المحلیة والعالمیة التی تؤثر فی الطلب علی الموالح المصریة قد استخدمت الدراسة نموذج انی متعدد المعادلات ، حیث أوضح أن أکثر العوامل تأثیرا علی متوسط نصیب الفرد السعودی من کمیة الصادرات المصریة من الموالح هو السعر التصدیری لسوریا ، والسعر التصدیری للأردن، إذ تشیر قیمة "ف" إلى معنویة المعادلة المقدرة إحصائیا عند مستوى 0.05، کما أظهر معامل التحدید المعدل أن حوالی 95% من التغیرات الحادثة فى متوسط نصیب الفرد السعودی من الصادرات المصریة من الموالح للسعودیة تعزى إلى المتغیرات المستقلة سالفة الذکر کما أظهرت نتائج التحلیل الاحصائی أن أکثر العوامل تأثیرا علی متوسط نصیب الفرد الروسی من کمیة الصادرات المصریة من الموالح هو سعر تصدیر ترکیا للموالح ، ومتوسط نصیب الفرد الروسی من الدخل القومی ، إذ تشیر قیمة "ف" إلى معنویة المعادلة إحصائیا عند مستوى 0.05، کما توضح قیمة معامل التحدید المعدل أن حوالى 81% من التغیرات فى متوسط نصیب الفرد الروسی من الصادرات المصریة من الموالح لروسیا تعزى إلى المتغیرات المستقلة سالفة الذکر .
2022-01-24T17:25:11.134Z
199,539,004
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1556/650.2019.31521", "MAG": null, "PubMedCentral": null }, "license": null, "status": "GREEN", "url": "http://real.mtak.hu/97119/1/650.2019.31521.pdf" }
Introduction: Despite all new promising agents of oncotherapy, it is still liver resection that gives potential curative solution for primary and secondary liver tumors. The size of tumorous liver section for resection means no question any more but major vessel infiltration of tumor proposes challenge in liver surgery. Patients and method: Retrospective analysis was carried out covering 33 patients who underwent liver resection in St. Janos Hospital Surgery Department between 1st May 2017 and 1st May 2019. Demographic, surgical, histological data and postoperative course were taken into consideration and comparison with two of our patients who needed vena cava excision simultaneously with liver resection. Results: Patients with liver resection only (LR) had a mean operation time of 91.7 minutes, while operation time for patients with cava resection (CR) was 250 minutes. The average amount of blood transfusion was 1.2 units (200 ml) in group LR and 5 units in group CR. Among LR patients, resection was rated R0 in 23 and R1 in 8 cases, R2 resection could be performed in 2 cases, in group CR in both cases R1 resection was registered. 5 patients with colorectal liver metastasis were operated after previous chemotherapy. Two patients underwent laparoscopic liver resection and two had synchronous colorectal and liver resection, one of these was treated via laparoscopic approach. Conclusion: Liver resections in case of large vessel (vena cava, hepatic vein) infiltrating by liver tumors are indicated the most challenging procedures of liver surgery. The relating literature refers to oncological liver resections with vena cava excision and reconstruction to be safe and applicable. Orv Hetil. 2019; 160(33): 1304-1310.
2022-02-08T05:38:04.939Z
244,240,375
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.53782/280", "MAG": "3203594995", "PubMedCentral": null }, "license": null, "status": null, "url": null }
O currículo é usado na Educação o tempo inteiro. Para avaliar as crianças, devemos ter um olhar sensível, a fim de verificar se estão se desenvolvendo e atingindo os objetivos estabelecidos no plano pedagógico. Trata-se de um trabalho constante e complexo, o qual deve ser aperfeiçoado para se tornar ainda mais minucioso, mais objetivo e mais claro, para que as famílias compreendam o processo e os critérios pelos quais seus filhos são avaliados. O currículo na Educação Infantil parte de um importante processo de ensino e aprendizagem, tornando-se tema de muitas pesquisas, debates e discussões acadêmicas. Avaliar tem por conceito não julgar, não apontar, mas acompanhar o percurso de vida da criança, por meio de registros e olhares, com a intenção de favorecer o seu desenvolvimento. É por meio do currículo que se pode avançar e construir conhecimento a partir do erro.
2022-01-27T08:16:51.451Z
238,816,784
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.21727/rs.v12i2.2462", "MAG": "3191525019", "PubMedCentral": null }, "license": "CCBY", "status": "GOLD", "url": "http://editora.universidadedevassouras.edu.br/index.php/RS/article/download/2462/1667" }
As coagulopatias estão associadas à elevada morbimortalidade, principalmente no paciente criticamente doente. Podem ser divididas em congênitas ou adquiridas, dentre as quais a coagulação intravascular disseminada (CIVD) tem maior prevalência. Conhecer como se distribuem no Brasil as coagulopatias no primeiro ano de vida e se representam importante causa de óbito é fundamental para se traçar estratégias de cuidados dos pacientes em risco. O objetivo deste trabalho é conhecer a importância das coagulopatias como causa de óbito através das taxas de mortalidade e mortalidade proporcional em menores de 1 ano no Brasil de 2006 a 2017. Foi realizado estudo ecológico de séries históricas das taxas de mortalidade e mortalidade proporcional por coagulopatias e por todas as causas em menores de um ano, no Brasil, de 2006 a 2017. Dados de nascidos vivos obtidos pelo SINASC / DATASUS / MS e óbitos obtidos no SIM/DATASUS/MS. As coagulopatias representaram 33% dos óbitos por doenças relacionadas ao sangue, sendo a principal causa neste grupo. A taxa de mortalidade foi de 2,10 por 100.000 nascidos vivos e mortalidade proporcional por todas as causas de 15,15%. Dentre as coagulopatias a CIVD foi responsável por 47,4%, sendo identificada como principal causa de mortalidade por coagulopatia no grupo etário estudado, a qual possui diversas causas precipitantes, sendo a mais importante nessa população a infecciosa. Conhecer o perfil epidemiológico de mortalidade infantil é importante para instituir medidas de melhoria da assistência em saúde, fornecendo subsídios para o desenvolvimento de intervenções e redução da mortalidade.
2022-07-10T04:34:08.305Z
96,592,273
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3952/PHYSICS.V50I2.1981", "MAG": "2057434552", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The investigation of the ozone formation and destruction is of great interest because ozone influences the atmospheric chemistry and plays an important role in the climate change. The ground-level ozone lifetime alters depending on physical and chemical properties of the locality, meteorological factors, atmospheric turbulence, and other conditions. In this paper, the method of estimation of the ozone lifetime under rural conditions is presented. The discrepancy between the solar intensity as well as related turbulent air mixing maximum and the ozone concentration maximum during the day was used in the lifetime calculations. The solar radiation intensity and duration were taken as main parameters in calculating the ozone lifetime by estimating the ozone enrichment at the ground level. In the calculations the least-squares method was applied. The groundlevel average ozone lifetime was estimated to be in the range of 3.6–5.6 hours at the rural Preila station and in the range of2.8–3.9 hours at the Rūgsteliskis station during different seasons. Keywords: ozone lifetime, solar radiation intensity and duration, seasons, rural conditions
2022-09-09T13:01:56.044Z
3,835,823
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1371/journal.pone.0022693", "MAG": "2084057728", "PubMedCentral": "3145655" }, "license": "CCBY", "status": "GOLD", "url": "https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0022693&type=printable" }
Background Socioeconomic, demographic, and geographic factors are known determinants of stroke and myocardial infarction (MI) risk. Clustering of these factors in neighborhoods needs to be taken into consideration during planning, prioritization and implementation of health programs intended to reduce disparities. Given the complex and multidimensional nature of these factors, multivariate methods are needed to identify neighborhood clusters of these determinants so as to better understand the unique neighborhood profiles. This information is critical for evidence-based health planning and service provision. Therefore, this study used a robust multivariate approach to classify neighborhoods and identify their socio-demographic characteristics so as to provide information for evidence-based neighborhood health planning for stroke and MI. Methods and Findings The study was performed in East Tennessee Appalachia, an area with one of the highest stroke and MI risks in USA. Robust principal component analysis was performed on neighborhood (census tract) socioeconomic and demographic characteristics, obtained from the US Census, to reduce the dimensionality and influence of outliers in the data. Fuzzy cluster analysis was used to classify neighborhoods into Peer Neighborhoods (PNs) based on their socioeconomic and demographic characteristics. Nearest neighbor discriminant analysis and decision trees were used to validate PNs and determine the characteristics important for discrimination. Stroke and MI mortality risks were compared across PNs. Four distinct PNs were identified and their unique characteristics and potential health needs described. The highest risk of stroke and MI mortality tended to occur in less affluent PNs located in urban areas, while the suburban most affluent PNs had the lowest risk. Conclusions Implementation of this multivariate strategy provides health planners useful information to better understand and effectively plan for the unique neighborhood health needs and is important in guiding resource allocation, service provision, and policy decisions to address neighborhood health disparities and improve population health.
2022-09-13T19:39:45.264Z
154,769,923
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2307/1239301", "MAG": "2079830194", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The impacts of major exogenous forces on the farm sector are measured using a seven equation model. Annual estimates of the parameters of an aggregate Cobb-Douglas production function are obtained by using relative market shares. First order conditions for four groups of inputs are derived. Time series and ordinary least squares are used to estimate the supply for farm labor and the demand for farm output. Technological change, exogenous price changes, and population growth are the major exogenous influences. Roughly 90 percent of farm program benefits have accrued to landowners.
2022-09-12T05:20:49.253Z
191,490,506
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.4000/VERTIGO.14419", "MAG": "2084861284", "PubMedCentral": null }, "license": null, "status": null, "url": null }
La question des dechets est devenue au fil du temps de plus en plus problematique en raison notamment de leur augmentation considerable. Cependant, la prise de conscience de la necessite d’une gestion des ordures – ordures menageres, excrements, boues, etc. – efficace n’est apparue que tardivement dans les esprits. L’objectif de cet article est donc de presenter, a travers une approche essentiellement bibliographique, la maniere dont les humains ont cohabite et ont gere leurs dechets de la Prehistoire a la fin du XIXe siecle.
2022-10-24T16:03:47.550Z
42,797,397
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1177/1077801204271722", "MAG": "2096765203", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This article examines the effect of convictions for domestic violence or a related charge on the recidivism of batterers. Findings indicate that convictions reduce the likelihood of domestic violence recidivism. The variance explained by the conviction variable is modest; however, conviction remains significant when the batterers’histories of domestic violence charges and other background variables are introduced. The article also explores the associations between batterers’background characteristics and court convictions, as well as the effect of sanctions on the recidivism of convicted batterers.
2022-12-12T10:48:00.366Z
59,516,999
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1071/MF03021", "MAG": "2114759647", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This study explores how differences in ionic composition of south-eastern Australian saline lake waters, caused by path differentiation according to the Eugster–Jones–Hardie models of solute evolution and halite recycling, influence species composition of ostracod faunas. Ostracod occurrences are reported as physiologically important ionic ratios set in a marine–meteoric framework, with chemical boundaries determined by mixing and evaporation models. The occurrence of halophilous ostracods coincides with changes in the ionic structure of lake waters. Chemical diversity is found to be biologically important, with most ostracods preferring a specific pathway of the Eugster–Jones–Hardie models. Path preference predominantly reflects the different tolerance ranges of species to a combination of Na+/H+, Na+/Ca2+ and alkalinity/Cl– activity ratios, which probably govern acid–base balance and Na+ and Ca2+ regulation. An alkalinity/Cl– activity ratio of ~–2.3 corresponds to the main division in the ostracod data and reflects the abrupt change in alkalinity/Cl– ratios that occurs when a seawater-like solute matrix is diluted with a large amount of meteoric water (95%). Most halobiont ostracods occur in waters enriched with Na–Cl as a result of halite recycling. Evidence is presented that the same geochemical processes are relevant to other aquatic organisms (e.g. zooplankton, diatoms, insects) found in salt lakes.
2022-12-12T16:27:02.583Z
220,128,401
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.7717/peerj.9375", "MAG": "3036129899", "PubMedCentral": "7307571" }, "license": "CCBY", "status": "GOLD", "url": "https://doi.org/10.7717/peerj.9375" }
Grazing as one of the most important disturbances affects the abundance, diversity and community composition of arbuscular mycorrhizal (AM) fungi in ecosystems, but the AM fungi in response to grazing in wetland ecosystems remain poorly documented. Here, we examined AM fungi in roots and soil in grazing and non-grazing plots in Zoige wetland on the Qinghai-Tibet plateau. Grazing significantly increased AM fungal spore density and glomalin-related soil proteins, but had no significant effect on the extra radical hyphal density of AM fungi. While AM fungal richness and community composition differed between roots and soil, grazing was found to influence only the community composition in soil. This study shows that moderate grazing can increase the biomass of AM fungi and soil carbon sequestration, and maintain the AM fungal diversity in the wetland ecosystem. This finding may enhance our understanding of the AM fungi in response to grazing in the wetland on the Qinghai-Tibet plateau.
2022-12-20T00:48:57.452Z
73,574,551
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.12915/PE.2014.12.13", "MAG": "2139377657", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The paper describes the investigation of saturation effect in newly developed MgAl2O4:Co saturable absorber with the aim of thermally bounding it with the active media such as erbium glasses. On the basis of the experimental results the most important parameters, from the point of view of laser generation, such as ground state absorption cross section, excited state absorption cross section and dissipative losses were calculated. The comparison of this parameters with the parameters presented in the literature was done showing the advantages of the newly developed saturable absorber over commercially available ones.
2022-02-11T08:56:39.007Z
136,739,413
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1364/BODA.2013.BTH1A.2", "MAG": "1966314134", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Random access two-photon microscopy based on acousto-optic deflector has been developed to track the fast activation pattern of the neuronal networks, including the principle, the instrumentation, and signal interpretation.
2022-02-09T10:59:06.939Z
138,754,564
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2115/FIBER.49.8_448", "MAG": "2323919384", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Characteristics of Water Absorption of Cotton Terry Towel Treated with Household Softeners Kunio Yoshizumi*1, Kyoko Harada*1, Yukiko Kobayashi*1, Miho Aita*1; Masuzo Nagayama*2, and Yoko Yamaguchi* 2 *1 Kyoritsu Women's University, 2-2-1 Hitotsubashi, Chiyoda-ku, Tokyo, 101 Japan *2 Kyoritsu Women's Junior College, 2.2-1 Hitotsubashi, Chiyoda-ku, Tokyo, 101 Japan Abstract: Water absorption of a cotton towel treated with two types of household softeners was examined by Larose method. The conventional and latest ones contain distearyl dimethyl ammonium chloride and dioleyl dimethyl ammonium chloride, respectively, as a softener base. The former caused the deteriorated water absorption of the towel according to the increase of its bath concentration. However, almost normal water absorption was found in the latter's case over all the concentration range examined here. The latest softener would give the consumer's satisfactory water absorption even in its excess use. In addition, the consistency between Larose and Bilec methods was observed in the order. (ReceivedSeptember 10, 1992)
2022-06-08T17:56:05.999Z
144,944,898
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3989/arbor.2014.770n6002", "MAG": "1554686809", "PubMedCentral": null }, "license": "CCBY", "status": "GOLD", "url": "http://arbor.revistas.csic.es/index.php/arbor/article/download/1983/2369" }
Abstract My treatment of Gómez de Avellaneda is based on the principle that Seville — described in detail in her account of her travels with her cousin, Eloísa — marks a turning point in her literary career between 1838 and 1840: it was then that she became known as a poet through newspaper reports; that she wrote her final novel, Sab; and that her play, Leoncia — though lacking maturity as her first attempt in this genre — was performed successfully. ‘Letters to Cepeda’, about her first and passionate love, are today the most interesting documents of this period from both the autobiographical and metaliterary points of view. In fact, all the works of this period can be read as autobiographical dramas which anticipate her peculiarly female destiny. After a prolific literary career, Seville becomes the setting for the final stage of her career and for the preparation of her complete works in the late 1860s. By now she is widowed, prematurely aged, and tired. The final Madrid phase is brief, marked by her death and burial in the Sacramental San Martín attended by a small group of mourners. Vanitas vanitatis! In accordance with her last wishes, her remains now rest in Seville’s San Fernando cemetery. This article, focusing on the Seville years of the then increasingly famous writer, is conceived as a tribute on the bicentennial of her birth.
2022-08-31T15:06:50.907Z
253,343,194
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.18540/jcecvl8iss8pp14822-01e", "MAG": null, "PubMedCentral": null }, "license": "CCBYNCSA", "status": "GOLD", "url": "https://periodicos.ufv.br/jcec/article/download/14822/7528" }
O presente trabalho propõe uma integração energética a partir de um ciclo de trocadores de calor dentro de uma planta produtora de xilitol, com o objetivo da redução dos custos de operação e emissões de gases poluentes ao meio ambiente. A partir do fluxograma de produção de xilitol, foi possível realizar o levantamento das correntes quentes que precisam ser resfriadas e das correntes frias que precisam ser aquecidas, e assim realizar o posicionamento dos trocadores de calor em formato cíclico para que todas as correntes de saída dos trocadores de calor sejam aproveitadas, reduzindo assim o consumo com utilidades (vapor e água) externa ao processo para aquecer ou resfriar os equipamentos que necessitam atingir uma determinada temperatura. Os cálculos do balanço de energia pro processo foram realizados para os dois cenários estudados, sem integração e com integração energética na presença de um ciclo de trocadores de calor. A partir desses resultados conclui-se que houve uma redução no consumo de utilidades quentes (vapor) de 100% e utilidades frias (água) de 41,97%.  Assim, é possível afirmar que a integração energética por ciclo de trocadores de calor nesse caso, tornou o processo viável desde o ponto de vista produtivo ao ambiental, pois além das reduções com o custo de produção, devido a economia com utilidades quentes (vapor) e utilidades frias (água), também é possível reduzir a emissão de gases na atmosfera
2022-11-06T17:23:44.729Z
7,651,725
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1093/nar/5.1.205", "MAG": "2134901903", "PubMedCentral": null }, "license": null, "status": "GREEN", "url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC341972" }
Initiation of adenovirus transcription was analyzed by incubation of isolated nuclei from virus infected cells in the presence of beta-32P GTP or beta-32P ATP. Nucleotide analysis of RNA from nuclei incubated with beta-32P GTP shows that the label is incorporated exclusively into pppGp and ppGp. Under similar incubation conditions, the label from beta-32P ATP was incorporated primarily into the 5' phosphate of 5', 3' mononucleoside diphosphates, but label was also detected in pppAp, pppGp and in the 3' nucleoside monophosphates. Analysis of RNA, synthesized in the presence of different concentrations of alpha-amanitin, shows that only RNA polymerase III initiates virus specific transcription in isolated nuclei. The virus specific transcripts containing pppAp and pppGp in their 5' termini were identified as the 5.5S and 5.2S viral RNA species by hybridization and finger printing.
2022-12-17T08:31:07.262Z
51,905,038
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/TIFS.2018.2850319", "MAG": "2810685556", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The SAT-based attacks are extremely successful in deobfuscating the traditional combinational logic locking and IC camouflaging schemes. While several SAT-resilient protection schemes that increase the minimum query count of the attack have been proposed recently, none of them satisfy the output corruptibility (error) criteria. Therefore, most of them were combined with high corruptibility schemes to achieve both corruptibility and high query count. These “compound” schemes are successful since existing SAT attacks are agnostic to the corruptibility of the protection scheme. In this paper, we propose an approximate SAT-based attack framework which focuses on the iterative convergence of an attack toward a better solution. This helps our attack reduce a compound scheme to a standalone SAT-resilient scheme. In addition, we relate the problem of minimum query count to a well-known graph problem, and we propose a novel technique to increase the corruptibility of SAT-resilient protection schemes in a controllable manner. This creates protection schemes that have both high query count and corruptibility. Furthermore, due to the approximation resiliency property of these schemes, approximate attacks provide no advantage over exact attacks when attacking them.
2022-12-19T12:54:34.302Z
122,684,450
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1088/0022-3727/46/50/505308", "MAG": "2145905560", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Using first-principles calculations, we have systematically investigated the geometric and electronic structure of MoS2–WS2 and MoS2–MoTe2 monolayer (ML) heterostructures. Analysis of the variation of the total density of states and partial density of states of the specific atoms in the interfaces demonstrates that the two heterostructures show rather different properties and different changes from the initial MoS2 ML. The MoS2–WS2 ML heterostructure is still a semiconductor with a band gap of 1.58 eV, which is smaller than that of MoS2 and WS2 MLs. However, the strong interactions between MoS2and MoTe2 at the interfacial sites induce the MoS2–MoTe2 ML heterostructure to display metallic characteristics. Our results indicate that the ML heterostructures of MoS2–WS2 and MoS2–MoTe2 are expected to be a possible way to extend the application of the transition-metal dichalcogenides.
2022-12-24T18:19:58.066Z
251,077,376
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1039/d2cc03592h", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
Herein, two mitochondria-targeting photosensitizers (PSs, CCVJ-Mito-1 and CCVJ-Mito-2) that exhibit a turn-on fluorescence response towards increasing viscosity are reported. Notably, CCVJ-Mito-2 exhibits absorption in the near-infrared (NIR) region, and can be employed as a NIR PS targeting mitochondria and a fluorescent probe for tracking mitochondrial viscosity changes during photodynamic therapy (PDT). This dual functional PS can help to shed light on the dynamic changes of the cellular microenvironment during PDT and further guide the PDT process.
2022-12-26T16:40:19.188Z
118,630,975
{ "externalids": { "ACL": null, "ArXiv": "1904.08295", "DOI": "10.1051/0004-6361/201832805", "MAG": "3100835580", "PubMedCentral": null }, "license": null, "status": "BRONZE", "url": "https://www.aanda.org/articles/aa/pdf/2019/06/aa32805-18.pdf" }
Context. In tight binary star systems, tidal interactions can significantly influence the rotational and orbital evolution of both stars, and therefore their activity evolution. This can have strong effects on the atmospheric evolution of planets that are orbiting the two stars. Aims. In this paper, we aim to study the evolution of stellar rotation and of X-ray and ultraviolet (XUV) radiation in tight binary systems consisting of two solar mass stars and use our results to study planetary atmosphere evolution in the habitable zones of these systems. Methods. We have applied a rotation model developed for single stars to binary systems, taking into account the effects of tidal interactions on the rotational and orbital evolution of both stars. We used empirical rotation-activity relations to predict XUV evolution tracks for the stars, which we used to model hydrodynamic escape of hydrogen dominated atmospheres. Results. When significant, tidal interactions increase the total amount of XUV energy emitted, and in the most extreme cases by up to factor of ~50. We find that in the systems that we study, habitable zone planets with masses of 1 M⊕ can lose huge hydrogen atmospheres due to the extended high levels of XUV emission, and the time that is needed to lose these atmospheres depends on the binary orbital separation. For some orbital separations, and when the stars are born as rapid rotators, it is also possible for tidal interactions to protect atmospheres from erosion by quickly spinning down the stars. For very small orbital separations, the loss of orbital angular momentum by stellar winds causes the two stars to merge. We suggest that the merging of the two stars could cause previously frozen planets to become habitable due to the habitable zone boundaries moving outwards.
2022-12-30T01:18:53.073Z
56,261,787
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.7124/BC.0003F3", "MAG": "2027273501", "PubMedCentral": null }, "license": null, "status": null, "url": null }
DNA fingerprinting is known to be widely used in medical expertise, in­ vestigations needing genetic markers, population studies, practical selec­ tion etc [1, 2]. A probe based on M13 phage sequences belongs to those adapted for genomic profiles researches [3]. This probe is convenient to detect hypervariable genome regions in representatives of different taxonomic groups because of its universality [2]. To obtain clear hybridization data, it is necessary to have probes of high specific radioactivity. To obtain such a label of M13 DNA, the reaction of incomplete synthesis on the single-stranded phage form is often used, 17 nucleotides containing primer being introduced into this system [4]. Such an approach, however, is meets some difficulties, op­ timal conditions for probe synthesis and hybridization are still to be found. Therefore we propose a protocol permitting synthesis of a high labelled one-stranded probe using a specific primer. For this aim, a 15-meric oligonucleotide 5'-TTCATAATCAAAATC-3', being a homolog of a region localized at the З'-end of phage gene III has been synthesized; in such a way we obtain the possibility to synthesize exclu­ sively a fragment containing hypervariable repetitive sequences using Klenow fragment [5]. The purification of the single-stranded probe has been made, as usually, in denaturative polyacrylamide gel followed by elution. To simplify this protocol, we propose an approach described below. After completion synthesis probe, 8 M ammonium acetate (up to 2 M) as well as yeast tRNA (50—100 ng/ml) and ethanol (2.5 volumes) are added. The mixture is to be incubated at room temperature (15 min) and run at the Eppendorf centrifuge during 10 min. The pellet is to be washed with ethanol solution (70°), partly air-dried, dissolved in water and put on nitrocellulose filter. This material is of significant binding capacity for single-stranded DNA (80—100 u.g/cm), hence little pieces of nitro­ cellulose (0.1—0.2 cm) can to be used. The air-dried filters are to be Incubated in the vacuum at 80 °С during 1—2 hours. These conditions lead to the irreversible single-stranded fragment adsorbtion on the fil­ ter, with the two-stranded phage fragment being non-adsorbed; the latter can be separated from the matrix after boiling of the filters in distilled water (5 min). The probe separated may be later used for hybridization [6].
2022-02-11T19:29:41.447Z
237,760,331
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.32999/KSU2663-2691/2021-86-19", "MAG": "3177559151", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Мета. Метою цієї статті є виявлення специфіки перекладу англомовних термінів, які вживаються у межах підмови птахів- ництва українською мовою, особлива увага приділена багатозначним та омонімічним термінологічним одиницям. Методи. Матеріалом дослідження є близько 700 англійських зоотехнічних термінів птахівницького напряму, які були відібрані з відповідних англійських фахових текстів (наукових статей та науково-дидактичних матеріалів, інструкцій для фахівців). Дослі- дження методологічно базується на системно-структурному підході, що дозволяє провести синхронний аналіз мовних явищ на основі зв’язків і відношень між цими елементами. Аналіз парадигматичних відношень термінології проводився на основі принципів семантичного поля та тематичної організації терміно-понять. Було також застосовано описовий та порівняльний методи. Результати. Проведений огляд літератури підтвердив неодностайність дослідників у тлумаченні омонімії та багатознач- ності в термінології. Окреслено проблеми під час перекладу омонімічних та багатозначних термінів підмови птахівництва та запропоновані можливі шляхи вирішення цих проблем. Описано види термінологічної омонімії та полісемії простих оди- ниць та абревіатур. З’ясовано, що найбільші складності виникають у перекладі внутрішньогалузевих простих термінів. Висновки. Проведений аналіз показав, що під поняттям «термін» розуміють одиниці, що застосовуються виключно в нау- ково-технічному контексті чи в певній галузі, загальнонародні слова, які мають загальновідомі значення; у роботі з полісеміч- ними та омонімічними термінами найбільшу складність становлять внутрішньогалузеві слова та словосполучення, оскільки їх переклад цілком визначається контекстом. Коректність перекладу омонімічного чи багатозначного терміна вимагає обі- знаності у галузі птахівництва та розуміння змісту англійського терміна, а також знання відповідної термінології української мови. Українське перекладознавство має накопичувати, обробляти та систематизувати термінологічний апарат зоотехнічної галузі загалом та птахівництва зокрема; укладання двомовних довідників та словників для цієї галузі сільського господарства також має бути пріоритетним.
2022-06-04T14:18:43.814Z
176,565,145
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.5216/VIS.V5I1.18038", "MAG": "1533120366", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Este artigo investiga a interacao humana com outros animais e sua representacao cultural nos contextos artistico e cientifico. Concentra-se no dialogo entre duas posi coes epistemologicas distintas: o conhecimento gerado pelas ciencias naturais e aquele que emerge da arte con temporânea, mais especificamente dos debates decor rentes do uso da telepresenca. Sao discutidas questoes teoricas, politicas e esteticas relacionadas a Ciberarte e ao uso da telepresenca no contexto artistico. O artigo tambem faz referencia a obra Franca! que propicia, atraves da telepresenca, a observacao a distância do trabalho de biologos que estao pesquisando o comportamento das baleias Franca no litoral sul do Brasil. Palavras-chave: telepresenca, colaboracao arte e ciencia, Baleia Franca
2022-07-19T23:37:05.280Z
251,361,999
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.21273/jashs.106.5.589", "MAG": null, "PubMedCentral": null }, "license": "CCBYNCND", "status": "HYBRID", "url": "https://journals.ashs.org/downloadpdf/journals/jashs/106/5/article-p589.pdf" }
Hardwood bark, amended with either urea (CO(NH2)2) or ammonium nitrate (NH4NO3) was composted in 210 liter drums at 10 to 40°C or heated to 55°. In the supplemental heat composted (SHC) bark amended with CO(NH2)2, pH increased to 6.8 to 7.4 within the first week. Bark amended with CO(NH2)2 generated more heat than bark amended with NH4NO3. Phenolic content decreased (as indicated by the Folin-Ciocalteu (F-C) method), and germination percentage of Lactuca sativa L. cv. Grand Rapids seed in water extracts of bark samples increased with time. Additions of polyvinylpyrrolidone (PVP) to extracts decreased phenolic content and increased the percentage of seed germination. Plant growth assays using Chrysanthemum × morifolium Ramat ‘Bright Golden Anne’ revealed a possible N deficiency in SHC NH4NO3 treated bark. Plants grown in SHC CO(NH2)2 amended bark did not have as severe a N deficiency. As time of composting increased, naturally composted (NC) bark treated with either N source gave plant growth comparable to that of the control plants grown in a medium of peat:perlite:vermiculite:soil (3:2:2:1 v/v).
2022-09-08T10:59:11.512Z
252,541,870
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.11607/ijp.7829", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
This case report describes a new digital workflow for computer-assisted implant surgery in an edentulous patient using transitional implants to support a fixed surgical template and interim prosthesis. The accuracy of the final implant position using the described protocol was evaluated and compared to the outcomes obtained using other types of surgical templates. This novel digital approach appears to enhance the accuracy of implant positioning for edentulous patients and seems to be comparable to a tooth-supported surgical template.
2022-09-29T14:28:30.781Z
177,332,821
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1163/22134360-90001539", "MAG": "2020653030", "PubMedCentral": null }, "license": "CCBYNC", "status": "HYBRID", "url": "https://brill.com/downloadpdf/journals/nwig/6/1/article-p271_29.pdf" }
In een artikel, getiteld: „Een en ander over de bereiding van de Liberia-Koffie in Suriname" in het landbouw tijdschrift West-Indië No. 3 1923, werd door schr. dezes een exposée gegeven omtrent de bereiding van de Liberiakoffie zooals die daar vroeger en thans plaats heeft, met de ervaringen door de verschillende planters daarbij opgedaan. Verder werden in genoemde publicatie (voortaan aangeduid door I), eenige methodes aangegeven, waarmede getracht werd de kwaliteit der koffie, hetzij door nabehandeling van het product, hetzij door verandering van de bereiding, te verbeteren. Waar de nabehandeling van het product zijn bezwaren van verschillenden aard meebracht, werd ten slotte de verandering van de bereidingswijze voornamelijk bestudeerd. Deze komt neer op een verandering in de wijze waarop de gepulpte koffiebes van de pulp wordt ontdaan. De thans algemeen gevolgde methode is dat de gepulpte koffie in steenen of houten bakken wordt gefermenteerd. Nu werd op plantage „Jagtlust" een methode uitgewerkt om de pulp langs mechanisch-chemischen weg te verwijderen (verg. ook het artikel van den heer van Dorsten in het Landbouw Weekbl. voor Nederl. Indië, Mei 1923, waarin de heer van Dorsten eveneens pleit voor vervanging van het fermentatie-proces door een chemisch mechanisch proces met behulp van kalkmelk).
2022-09-30T01:37:41.108Z
252,480,196
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1093/jas/skac247.331", "MAG": null, "PubMedCentral": null }, "license": null, "status": "BRONZE", "url": "https://academic.oup.com/jas/article-pdf/100/Supplement_3/180/45963638/skac247.331.pdf" }
Increasing evidence supports the existence of a microbial community in bovine semen, and that this seminal microbiota may influence not only the male reproductive health, but also female and offspring health through microbial transfer. In this study, we evaluated seminal microbiota in beef bulls (BW= 503±7.2 kg) fed a common diet to achieve moderate (1.13 kg/d) or high (1.80 kg/d) rates of weight gain. Semen samples were collected at day 0 and day 112 of dietary intervention (n = 19 per group), and post-breeding (n = 6) using electroejaculation and the microbiota assessed using 16S rRNA gene sequencing, quantification of total bacteria by qPCR, and viable bacteria culturing. A complex and dynamic microbiota was detected in the semen, and the community structure changed significantly over the course of the study (R 2 = 0.126, P < 0.001) but remained unaffected by the dietary treatment (P > 0.05). Microbial richness (number of ASVs) increased from d0 (253 ± 12) to d112 (293 ± 14) while diversity (Shannon index) was reduced (P < 0.05). Twenty-seven bacterial phyla were identified across all samples, with Fusobacteriota (36.3%), Bacteroidetes (30.4%), Firmicutes (17.1%) and Actinobacteriota (14.9%) being the most predominant phyla. Total bacterial load declined over time (P < 0.05). Diet had no effect on alpha diversity metrics, microbial composition, or total bacterial concentration (P > 0.05). A total of 364 bacterial isolates were recovered under aerobic (n = 220) and anaerobic (n = 144) culturing conditions. These isolates represented 48 different genera within the Firmicutes (60%), Proteobacteria (25%), Actinobacteria (9%), Bacteroidetes (4%) and Fusobacteriota (2%) phyla. Bacillus, Staphylococcus, Escherichia, Enterococcus and Arthrobacter were the predominant genera. Overall, our results suggest that bovine semen harbors a rich and complex microbiota which changes over time but appears to be resilient to differential gains achieved via common diet.
2022-10-14T01:06:42.255Z
27,544,027
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3155/1047-3289.58.12.1579", "MAG": "1993387111", "PubMedCentral": null }, "license": null, "status": "BRONZE", "url": "https://www.tandfonline.com/doi/pdf/10.3155/1047-3289.58.12.1579?needAccess=true" }
Abstract Eleven ionic species and fine and coarse particle mass concentrations of fine (PM2.5) and coarse (PM10–2.5) particulate matter were investigated in Kaohsiung, southern Taiwan. The PM2.5 and PM10–2.5 particulate concentrations were 49–64 and 34–37 μg∙m-3, respectively. Fifty-five to 64% of the particulate matter less than 10 μm in aerodynamic diameter (PM10) mass was attributed to the PM2.5. PM2.5 concentrations at Daliao (a rural and industrial complex area) were higher than at Tzuoying (an urban and industrial complex area). Ionic species contributed 45–53% and 42–45% of PM2.5 and PM10, respect tively. Potassium ions (K+), sulfate (SO4 2−), and ammonium (NH4 +) were predominant in PM2.5, whereas sodium, calcium, and magnesium ions were foremost in PM10–2.5. Nitrate (NO3 −) existed in both the PM2.5 and PM10–2.5. Chloride (Cl−), NO3 −, and NH4 + concentrations were higher at night than during the day, and they were easily transferred into the gas phase by photochemical reactions and temperature-induced volatilization. The NH4 +/SO4 2− ratios were 2.6 and 2.5 at Daliao and Tzuoying, respectively, which indicated that both sampling sites were rich in NH4 +. Therefore, ammonium nitrate would be present in the area.
2022-12-03T06:33:24.516Z
159,411,787
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1111/jsbm.12533", "MAG": "2939950890", "PubMedCentral": null }, "license": "CCBYNC", "status": "GREEN", "url": "https://wlv.openrepository.com/bitstream/2436/622303/9/Wang_Shi_Particularistic_and_system_trust_2019.pdf" }
ABSTRACT Research on how trust develops and why it matters in family businesses is in development. Our study investigates the emergence and the evolution of trust in family business leaders. Drawing on the New Systems Theory, we also examine the impact of family influence on trust. Multiple semi-structured interviews were performed in three Chinese family businesses. Results suggest that relationship-based particularistic trust prevails at the start-up stage because of the void of governance mechanisms. As businesses grow, particularistic trust gradually gives way to institution-based system trust. Evidence further indicates high family influence catalyzes particularistic trust initially and restricts system trust subsequently.
2022-12-10T09:33:14.771Z
2,268,577
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2214/AJR.158.1.1309220", "MAG": "2031958210", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Differential diagnosis of small liver tumors is important, but is not always possible, even with angiography. To solve this problem, we introduced sonographic angiography, which combines sonography and angiography. The vascular pattern of a variety of hepatic nodules was evaluated with sonographic angiography, and the results were compared with those of conventional angiography. Sonographic angiography (sonography performed during intraarterial infusion of carbon dioxide microbubbles) was performed in 184 patients with a total of 222 hepatic nodules: 139 hepatocellular carcinomas, nine adenomatous hyperplasias, seven regenerative nodules, 21 hemangiomas, 33 metastases, seven lymphomas, one granuloma, and five focal nodular hyperplasias. Sonographic angiography detected a hypervascular pattern with peripheral blood supply in cases of hepatocellular carcinoma (sensitivity, 90%; specificity, 89%). Typical vascular patterns of adenomatous hyperplasia, hemangioma, metastasis, and focal nodular hyperplasia on sonographic angiography were hypovascularity (sensitivity, 100%; specificity, 91%), spotty pooling (sensitivity, 100%; specificity, 100%), peripheral hypervascularity (sensitivity, 64%; specificity, 100%), respectively. The detectability of hypervascularity was greater with sonographic angiography than with conventional angiography in hepatocellular carcinoma, metastasis, and hemangioma. Our experience indicates that sonographic angiography depicts characteristic vascular features that reflect the vascular anatomy of specific types of hepatic tumors, and thus is useful in the differential diagnosis of these lesions.
2022-12-20T20:48:34.260Z
32,845,341
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1111/J.1365-2605.2005.00629.X", "MAG": "2151605194", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This paper summarizes the consequences of exposure to chlormequat, a plant growth regulator, on reproduction in mammals. Plant growth regulators are chemicals used to manipulate plant growth, flowering and fruit yield. In grain crops, plant growth regulators are applied to promote sturdier growth and reduce the risk of lodging. Chlormequat is the most common plant growth regulator. Maximum residue limits of chlormequat in food products are 10 mg/kg in oat and pear, 3 mg/kg in wheat and rye, and 0.5 mg/kg in milk. In Denmark, results from experiments with pigs in the late 1980s showed sows that display impaired reproduction, mainly impaired oestrus, when fed grain from crop treated with chlormequat. Subsequently, the advisory body to the Danish pig industry recommended limiting the use of grain (maximum 30% of diet energy) from crop treated with chlormequat given to breeding stock due to the risk of reproduction problems. More recently, experiments have been conducted to evaluate the influence of chlormequat-treated wheat crop on reproductive function in male and female mice. These experiments showed that epididymal spermatozoa from mice on feed or water containing chlormequat had compromised fertilizing competence in vitro, while reproduction in female mice was not compromised. The estimated intake of chlormequat in the pig (0.0023 mg/kg bw/day) and the mouse (0.024 mg/kg bw/day) experiments was below the acceptable daily intake of 0.05 mg/kg bw/day. Reports from the industry do not show any effects at these low levels.
2022-12-26T19:56:54.149Z
5,498,678
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1039/c3cs60067j", "MAG": "2004091366", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Porous carbons and porous carbon nitrides are well known support materials. Some of these materials are, however, not only a geometric construct for immobilization, enabling mass transport at the same time, but contribute due to their extended electronic structure to a potential catalytic event as such. When appropriate band schemes and electron reactivity are chosen, immobilized metal nanoparticles can exhibit a highly enhanced chemical reactivity. This is due to electronic interaction and electron transfer between the metal and semiconductor, as introduced by Mott and Schottky for planar metal-semiconductor interfaces. A rational choice of mesoporous semiconductor and metal particle allows to create a new generation of catalysts and catalytic schemes with unparalleled performances. This tutorial review highlights the latest development in the synthesis and applications of mesoporous N-doped carbon and carbon nitride supported metal nanoparticles, and concentrates on the catalytic effect of the charge transfer between the metal nanoparticles and semiconductive components.
2022-12-31T18:00:14.333Z
189,113,242
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.17485/IJST/2018/V11I34/131520", "MAG": "2895323740", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Objective: This research was to identify the learning styles (EA) used by students in the program of Biology at the University of La Guajira (Colombia) and of the biomedical area of the University of the Lord of Sipan (Peru), in order to establish a direct relationship between these styles. Methods/Statistical Analysis: Subjects were surveyed 36 first half of the program of Biology at the University of La Guajira, and 36 in the second half of the biomedical area of the University of the Lord of Sipan. For the collection of the information was used the questionnaire learning styles Honey-Alonso (CHAEA). Findings: Subsequently, a descriptive analysis was performed and standard deviation of the data. The students of the University of La Guajira (Colombia), showed mainly a pragmatic style, in contrast to the students of the University of the Lord of Sipan (Peru), which showed mainly a reflective style. Application/Improvements: However, in both groups of students is considered to be a trend toward a mixed learning style. It is recommended to teachers to encourage students to strengthen the learning processes using various tools. Keywords: Active Learning, Learning Pragmatic, Learning Styles, Reflective Learning, Theoretical Learning
2022-01-24T22:46:00.186Z
144,534,112
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1002/TL.372", "MAG": "2024984085", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This autoethnographic account describes interconnections among a professor's personal prayer life, teaching, and research. The contextual frame for the story includes episodes and observations from a twelve-year span, encompassing postacademic tenure and promotion to the present.
2022-02-09T06:54:46.206Z
102,118,437
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1533/9780857095695.3.523", "MAG": "3023959142", "PubMedCentral": null }, "license": null, "status": null, "url": null }
: This chapter will review the different synthetic pathways of bread volatiles in conventional white bread. The influence of traditional and innovative raw materials and breadmaking processes on the formation of volatiles will then be discussed. Next, extraction and analytical methods used to identify volatiles that participate in bread aroma will be presented. Volatiles that have been identified in freshly baked white bread will be listed and the ones that are potent odorants highlighted. Finally, the techniques employed by the baking industry to enhance bread aroma will be described.
2022-02-10T10:00:12.703Z
97,060,905
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2186/PRP.1.41", "MAG": "2059462390", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Purpose : The aim of this study was to investigate the relationship between the changes in surface texture and the imbibition and volatilization of home reliners.Materials and Methods : The home reliners used in this study were Tafu Grip®, Polydent®, New Liodent®, and Cushion Collect®. Soft-Liner® was used as a control. The changes in the surface texture of the materials were observed using a stereoscopic microscope. Weight changes were measured to evaluate the imbibition and volatilization of these products after being kept in distilled water (37°C) and ambient air. After immersion, regression analysis was done. The relationship between the changes in surface texture and both imbibition and volatilization of the home reliners was investigated by canonical correlation analysis.Results : The surface texture of the home reliners tested changed rapidly after soaking when holes and grooves appeared. Soft-Liner® exhibited few changes. The amount of imbibition of the home reliners, except for Polydent®, increased with time, but the amount measured for Soft-Liner® decreased only slightly. The amount of volatilization of both the home reliners and Soft-Liner® increased with time. Results of the regression analysis showed that the coefficients of determination were highly significant in the quadratic equation. The result of the canonical correlation analysis indicated that there was a relationship between the changes in surface texture and volatilization of home reliners.Conclusion : Within the parameters of this study, it was learned that many grooves appear on a small number of ethanol-containing home reliners.
2022-02-10T13:51:51.458Z
241,985,198
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.30965/9783657781591_002", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
The purpose of this research is to investigate the emotions experienced by learners of the Hellenic Open University (HOU) during their studies. Furthermore, the factors that create positive or negative feelings to the learners are investigated, such as Information and Communication Technology (ICT), group meetings and written assignments. Data collection was carried out via a suitable questionnaire and semi-structured interviews. The sample of the research consisted of undergraduate and post-graduate students of the Hellenic Open University in particular 122 students answered the questionnaire and a another four (4) post-graduate students participated in the interviews. Finally, this paper confirms the dominant place occupied by emotions in the learning process, a place that was until recently entirely attributed to reason.
2022-07-09T05:02:59.228Z
251,358,831
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.55662/lpr.2022.701", "MAG": null, "PubMedCentral": null }, "license": null, "status": "BRONZE", "url": "https://thelawbrigade.com/wp-content/uploads/2022/05/Irfan-Ali-Thanvi-LPR.pdf" }
The pandemic known as COVID-19 has taken the entire globe with a blast. The outbreak which initiated in December 2019, has been reported to have spread across six continents of the world in just a single quarter. The UAE like many other developed countries of the world is trying its best to curb any further spread of the novel virus. Unfortunately, some sectors of the society have taken this situation to work in their vital interest to fulfil ulterior motives, while some others, due to the oblivion of the UAE law get jeopardized by the same token. This negligence on part of several people may turn costly. Hence, I as a lead author on UAE laws decided to research the entire scenario and provide certain plausible legal solutions to our valuable audience. The regulations of the UAE have drastically been amended during the current pandemic of COVID-19, enabling loads of revisions to existing laws. One of the most important issues during the lockdown has been to regulate food supplies and garner stocks. This has been an ancient practice but was never instituted under the prevalent laws of the UAE, as there was never a need for such an occurrence. Ever since the outbreak of COVID-19, as the UAE went under a complete lockdown, changing the world of all residents in a dramatic way. This book covers significant discussion on the impact of the pandemic on all walks of life including but not limited to education, health care, employment, trading, court procedures and many more. At Amazon Inc, we are trying our level best to apprise the public of the latest developments in various sectors due to the outbreak of the pandemic. Nonetheless, a disclaimer for the audience about these rules and regulations may be altered through the process of time.
2022-08-16T17:36:00.713Z
136,802,869
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1111/J.1151-2916.1987.TB04994.X", "MAG": "2078035989", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Microhardness anisotropy profiles for the (100) and (111) planes of single-crystal stoichiometric MgAl2O., spinel were determined at room temperature. The (100) microhardness profile has ahardness maximum in tiie [001] and a minimum in the [O11], which supports the previous suggestion that the primary slip system is the {111}〈11¯0〉. The microhardness of the (111) plane is independent of indenter orientation, also consistent, with a {111}〈11¯0〉 primary slip system. It is concluded that these microhardness profiles are in accord with other experimental observations that the {111}〈11¯0〉 is the primary slip system in stoichiometric MgAl2O4 spinel.
2022-09-07T16:51:19.456Z
94,968,332
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1002/ZAAC.19623140305", "MAG": "2022469536", "PubMedCentral": null }, "license": null, "status": null, "url": null }
MgLiBO3 wird leicht durch Zusammentempern oder Schmelzen der Komponenten erhalten. MgLi2B2O5 bildet sich in gleicher Weise, zerfallt aber beim Abkuhlen in MgLiBO3 und LiBO2. Der Zerfall wird durch rasche Abkuhlung verhindert. Beide Verbindungen schmelzen inkongruent. MgLiBO3 is easily prepared by tempering or melting a mixture of MgO and LiBO2. By the same method, MgLi2B2O5 is formed, but decomposes into MgLiBO3 and LiBO2 on normal cooling; quenching prevents this decomposition. Both Mg-compounds have in-congruent m-points.
2022-09-27T08:33:48.113Z
7,309,514
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1093/ndtplus/sfp120", "MAG": "2108213924", "PubMedCentral": "4421548" }, "license": "CCBYNC", "status": "HYBRID", "url": "https://academic.oup.com/ckj/article-pdf/3/1/68/1256026/sfp120.pdf" }
A 43-year-old African American with end-stage renal disease (ESRD) associated with membranous nephropathy and a previously failed renal transplant had received cinacalcet to treat his secondary hyperparathyroidism. Serum calcium and phosphorus levels remained within normal limits, and serum parathyroid levels had dropped significantly following treatment initiation. However, within 7 months, the patient experienced extensive necrotic bilateral medial thigh ulcers. These were biopsied and found to be a result of calciphylaxis. The patient ultimately required an urgent subtotal parathyroidectomy and recovered well with completely healed ulcers.
2022-12-02T12:01:51.560Z
128,489,931
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1190/1.1893037", "MAG": "2087983395", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This paper presents reflection P and SH field data, collected along two lines, lying approximately parallel and perpendicular to a major oriented vertical fracture set. In the vicinity of the tie point, these data demonstrate the effects of azimuthal anisotropy, i.e., that shear velocity is a function of polarization azimuth. Although the P-wave lines tie, the SH lines do not. One line shows progressive (time-variant) time delays of the shear-wave reflection arrivals, relative to the corresponding arrivals on the other line. Also, for some reflection events, there is a marked difference in shear-wave reflection amplitudes on the two lines. These features are consistent with those expected to result from the known fracture sets. To their knowledge, this is the first published seismic reflection field data which show, and in which are recognized, these effects of azimuthal anisotropy. The effects of anisotropy are particularly clear because the lines lie approximately along the principal axes of the anisotropy, so that the effects of shear-wave splitting are minimized.
2022-09-14T19:40:58.425Z
218,470,948
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1128/MRA.01515-19", "MAG": "3021276058", "PubMedCentral": "7193940" }, "license": null, "status": null, "url": null }
Staphylococcus aureus strain TX0117 is a methicillin-susceptible bacterium with type A beta-lactamase exhibiting a high cefazolin inoculum effect. TX0117 was cured of blaZ, yielding TX0117c with increased antimicrobial peptide resistance. The sequencing and genome assembly of TX0117 elucidate six mutations between TX0117 and TX0117c, including relA truncation and mnA_1 substitution. ABSTRACT Staphylococcus aureus strain TX0117 is a methicillin-susceptible bacterium with type A beta-lactamase exhibiting a high cefazolin inoculum effect. TX0117 was cured of blaZ, yielding TX0117c with increased antimicrobial peptide resistance. The sequencing and genome assembly of TX0117 elucidate six mutations between TX0117 and TX0117c, including relA truncation and mnA_1 substitution.
2022-12-18T00:23:17.290Z
7,601,257
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1006/GCEN.1998.7155", "MAG": "1993171427", "PubMedCentral": null }, "license": null, "status": null, "url": null }
One of the most intriguing characteristics of the luteinizing hormone-releasing hormone (LHRH) neuronal system in mammalian species is the pulsatile release pattern of the peptide from the hypothalamus into the portal circulation, which is essential for the maintenance of normal reproductive function. In this review article the new concept that LHRH neurons possess an endogenous pulse-generating mechanism, but this is modified by other neuronal and nonneuronal inputs is discussed.
2022-12-19T18:01:28.719Z
240,618,906
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.24014/RMSI.V7I2.13182", "MAG": "3201370659", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Meningkatknya kasus positif-19 di Indonesia sangat berdampak di berbagai bidang terutama bidang pendidikan. Kementrian Pendidikan dan Kebudayaan Indonesia telah menyiapkan sebuah portal media pembelajaran Rumah Belajar – Kelas Maya dimana setiap daerah memiliki akses masing-masing. Untuk wilayah Sumatera Barat diberi nama Kelas Maya – Si Cadiak Pandai . Penerapan Media Pembelajaran ini pada SMK N 1 Kota Bukittinggi berlangsung semenjak pandemi Covid-19. Namun perlu kita ketahui penerimaan pengguna terhadap teknologi yang baru dikembangkan dan memiliki beberapa hambatan pada saat menggunakannya. Sehingga perlu dilakukan analisa terhadap tingkat penerimaan media pembelajaran online Kelas Maya – Si Cadiak Pandai menggunakan Technologhy Acceptance Model dengan pendekatan Structural Equation Model dan Partial Least Square . Hasil yang diperoleh dari penelitian ini adalah hipotesa yang telah dirancang pada tenaga pendidik berpengaruh secara signifikan terhadap penelitian dan pada peserta didik ditemukan dua hipotesis yang tidak berpengaruh secara signifikan. Rekomendasi penelitian adalah memberikan pelatihan dan buku panduan ( manual book ) sehingga dapat meningkatkan faktor kemudahan dan kegunaan pengguna dalam memahami media pembelajaran online Kelas Maya - Si Cadiak Pandai . Penerimaan media pembelajaran online , Technologhy Acceptance Model , Structural Equation Model , Partial Least Square , Covid-19.
2022-01-24T22:54:07.546Z
73,581,064
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.33552/ACRCI.2018.01.000509", "MAG": "2906058972", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Rectal cancer is 4-6% of all malignant tumors in humans (8-9 places). Among malignant lesions of rectum, it is 80%. Rectal cancer is more common in the age group 40-60 years and mostly in men (3:2). Patients with stage III-IV process constitute the overwhelming majority-81.2%. Initial form (stage I), in which surgical treatment guarantees almost 100% 5-year survival rates are only operations 3.9% [1,2]. For staging of timorous process and identify clinical prediction, widely used classification C.E. Dukes. It which into account two main pathological indication is the depth of germination of tumors in the intestinal wall and the presence of metastases in the lymph nodes. So, stage and to cases in which the growth of the tumor is limited to the wall of the rectum; in this stage the tumor spreads to surrounding tissues, but metastases in the lymph nodes do not exist; stage c is swelling with any degree of local dissemination with the presence of regional lymph node metastasis. The most widespread and recognized international classification of colorectal cancer, the proposed International Anticancer Union using characters TNM (Tumor, Metastases, Nodules). Clinical manifestations colorectal cancer depends on the stage of the disease, the nature of the growth of the tumor and its location [1, 3,4]. The most frequent and constant symptom of colorectal cancer is bleeding. It occurs in both the early and later stages and in 75-90% of patients. It is often confused with hemorrhoids [5,6]. The second most symptoms are different types of bowel function disorders. Pain sensations appear when local spread of the tumor, especially as it moves to the surrounding organs and tissues [7,8].
2022-02-11T08:55:25.012Z
225,414,113
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.32584/JIKJ.V3I3.646", "MAG": "3048261422", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Psychosocial development will be disrupted if parents are wrong in educating children. Children experience verbal abuse from caregivers, this is because caregivers want to discipline children, but children do not know their developmental tasks so verbal abuse occurs. Caregivers like to shout when calling children, use harsh words, speak ill of children in public, refer to children as children stupid and naughty. Developments that occur at school age require stimulation to avoid various deviations. This study aims to determine the psychosocial development of school age children before and after the provision of therapeutic group therapy for school age. Quasi experiment research design with pre and post test study design without control group. The research sample was students in grades 4, 5, and 6, physically and psychologically healthy, totaling 72 children. The sampling technique uses purposive sampling. The psychosocial development questionnaire that has been declared valid and reliable consists of 8 items. Data were analyzed using frequency distribution and chi square test. The results showed that before being given therapy 54% of children were at abnormal psychosocial development and after being given therapy there were 98% of children at normal psychosocial development. The results of the bivariate analysis showed the value of p = 0.000 (α = 0.05). There was an increase in the psychosocial development of school-age children as an effort to prevent psychosocial developmental delays by 52%.
2022-02-08T00:12:28.764Z
122,837,674
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1002/QJ.49709841812", "MAG": "2119497379", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Four inexpensive solarimeters were compared with a standard. Mean errors (on a daily basis) were 5 per cent for the Gunn-Bellani, 9 per cent for the Campbell-Stokes, 10 per cent for the bimetallic actinograph and 12 per cent for the Sol-a-Meter. The corresponding weekly errors were 2–5 per cent, 3 per cent, 3.5 per cent and 4.5 per cent. A fifth instrument was not included because daily totals were difficult to obtain.
2022-09-02T03:25:56.316Z
57,564,753
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1162/ling.2008.39.1.147", "MAG": "2045215159", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Culicover and Jackendoff (2005) argue that VP structure with adjunct modifiers is flat: both complements and adjuncts are equally sisters of V. Their arguments center around the apparent misbehavior of do so as a replacement for a syntactic VP constituent. However, several of these arguments are inconclusive. The rule that Culicover and Jackendoff offer for do so does not fare better overall than does the hierarchic VP account of do so.
2022-09-04T17:54:05.195Z
144,192,254
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1177/039219210004819005", "MAG": "1996959135", "PubMedCentral": null }, "license": null, "status": null, "url": null }
corresponding adjective? Does ’economics’ refer to a specific relationship between ends and means, as some think, or is it defined, more prosaically, as the satisfaction of material needs? Is it a category of specific facts or a praxeology of goal-oriented action? Some interesting debates on the matter, which have brought formalist, substantivist, and Marxist writers into conflict, have revealed marked ideological distortions, some reductionism, and finally epistemological positions that were difficult to reconcile. In the following pages I shall summarize these debates in order to introduce a new
2022-09-11T13:26:08.156Z
36,363,466
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1364/JOSAA.25.001728", "MAG": "2087975815", "PubMedCentral": null }, "license": null, "status": null, "url": null }
An implementation of the discrete dipole approximation for dipoles embedded in film on substrate is derived. It is capable of predicting the scattering response from various types of subsurface features such as trenches and contact-vias. An arbitrarily shaped subsurface feature is modeled with dipoles inside the film material on top of a substrate. Relative polarizability, direct interactions, and reflection interactions are derived and applied to construct a system of equations that are solved with an iterative method. The far-field scattering response is computed from the dipole moment solution of the system matrix with the help of the reciprocity theorem. The validity of the proposed method is compared with that of other existing theories, and the effect of film structure on far-field scattering is shown with high-aspect-ratio cylindrical contact-via models.
2022-09-15T00:52:33.832Z
15,323,959
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1172/JCI107689", "MAG": "2085146138", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Micropuncture, clearance, immunofluorescence and light microscopy techniques were used to study kidney structure and single nephron function in rats with autologous immune complex nephritis (AICN), a membranous glomerulonephritis developing over 5 to 20 mo, in the more acute and proliferative glomerular basement membrane (GBM) nephritis and in controls. Both models are known to have clinical counterparts in human disease. Kidney functional abnormalities correlated with the degree of architectural derangement. In both AICN and anti-GBM nephritis filtration fraction fell in direct proportion to the fall in glomerular filtration rate (GFR), renal plasma flow being unchanged. Fractional electrolyte excretion increased as the GFR fell. Despite marked heterogeneity of single nephron filtration rate (SNGFR) (AICN, 5-93 nl/min; anti-GBM, 0-50 nl/min) and of proximal tubular hydrostatic pressure (4-48 mm Hg), each nephron showed almost complete glomerulotubular balance, absolute reabsorption to the late proximal convolution varying directly with filtration rate. In addition SNGFR could be related both to proximal intratubular hydrostatic pressure and to calculated glomerular capillary pressure (Pg), being lowest in those nephrons with the highest intratubular pressure. Nephrons with very high filtration rates did not apparently reach filtration equilibrium. Mean SNGFR was significantly lower in the anti-GBM group, while calculated Pg was the same in both. This probably reflects the acute and diffuse involvement of the anti-GBM lesion with different filtration characteristics from the more chronic AICN disease. Tubular damage was more marked in AICN, and extraction of p-aminohippurate was reduced in this group.
2022-09-15T08:41:45.139Z
84,196,902
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1590/S0101-31222004000200007", "MAG": "2399992650", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The objective was to evaluate the effect of desinfection using sodium hypochloride and incubation procedures on the mold growth in the health test of peanut (Arachis hypogaea L.) seeds. Two experiments were carried out with two lots of cv. Botutatu. In the first experiment, the seeds were divided into two samples and one was submitted to immersion in sodium hypochloride. The incubation was realized in agar medium (PDA, CZ) and paper towel (blotter test and rolled paper), with or without water restriction. In the second experiment, the seeds were submitted to immersion in sodium hypochloride at 1, 2, 3, 5 and 10%, for one, three, five and ten minutes and they were incubated in PDA. The incubation methods in agar medium with water restriction promoted the highest recovery of Aspergillus spp. and Cladosporium spp. in the peanut seeds that had not been submitted to previous desinfection. Thef Rhizopus spp. and group Aspergillus niger incidence was lower in the disinfected seeds, regardless of the immersion period or sodium hypochlorite concentration.
2022-12-10T10:04:23.682Z
52,284,128
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3390/diagnostics8030067", "MAG": "2890842864", "PubMedCentral": "6164346" }, "license": "CCBY", "status": "GOLD", "url": "https://www.mdpi.com/2075-4418/8/3/67/pdf?version=1537342630" }
A novel qualitative point-of-care test of activated matrix metalloproteinase-8 (aMMP-8) using noninvasive oral rinse sampling procedures has been developed for the early detection of collagen breakdown indicating periodontal tissue destruction. The main object of this study was to assess the reliability of the test in a low-income setting to identify participants with history of periodontal destruction detected as alveolar bone loss (ABL) in radiographs. This cross-sectional study included 486 women who had recently delivered in rural Malawi. The aMMP-8 test and dental panoramic radiographs were taken within 48 h of delivery. The performance of the test in comparison to radiological examinations was tested by following the standards for reporting of diagnostic accuracy studies protocol (STARD) with respective statistical measures and 95% confidence intervals. From the 486 eligible participants, 461 mothers with complete data, aged from 15 to 46 years (mean 24.8, SD 6.0) were included in the analysis. ABL was identified in 116 of 461 participants. There was 56% agreement between the aMMP-8 test results and detected ABL (yes or no) in radiographs. Calculated sensitivity of the test was 80% (72–87%), specificity 48% (43–54%), positive predictive value 34% (31–37%), negative predictive value 88% (83–91%), positive likelihood ratio 1.55 (1.35–1.77), and negative likelihood ratio 0.41(0.28–0.60). The aMMP-8 test sensitivity and negative predictive value to identify the ABL cases were relatively high, but there was additionally a high rate of test-positive results in participants without ABL, especially in young mothers, leading to low overall agreement between the test results and radiological bone loss. Further longitudinal studies are needed to examine if the test positive subjects are in risk of future bone loss before the detectable signs of periodontitis in radiographs.
2022-12-12T10:35:26.890Z
59,272,534
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3149/CSM.0101.79", "MAG": "2022404673", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The “Lost Decade” of the 1990s, extending into the early 2000s, was a particularly crucial period in Japan’s recent history. On the one hand, these years were characterized by significant economic and social upheaval. At the same time, these years were witness to increasing challenges in the public sphere to societally dominant discourses, including those relating to gender, and in particular, masculinity. This paper provides an overview of the shifts in discourses of masculinity over these years. It contends that an understanding of the changes that occurred during the “Lost Decade” is necessary in order to appreciate the dynamics of men’s lives in Japan today.
2022-12-13T05:25:25.715Z
63,119,029
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3724/sp.j.1001.2008.01051", "MAG": "2352502666", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Computer architecture simulation is an integral part of modern computer design process. Simulation can help architects reduce the time and cost of computer architecture design dramatically. However, difficulties of constructing simulators, long simulation time, and poor accuracy limit the effectiveness of simulation. Many researchers have proposed a wide range of approaches to resolving the three main problems, which are still open. Meanwhile, new challenges start to emerge for future computer architecture simulation. This paper investigates the history of computer architecture simulation, classifies and compares the existing methodologies and technologies, and analyzes the challenges to help architects select, develop, or research on simulators. A brief description of the simulator SimIPF design is provided as well.
2022-12-18T09:48:37.669Z
32,220,810
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/ICSD.2010.5568256", "MAG": "2005321358", "PubMedCentral": null }, "license": null, "status": null, "url": null }
We measured mechanical properties of individual mammalian cells (U937 monocytes and CHO, see below) in suspension by trapping and stretching them in time-varying, non-uniform electric fields. To demonstrate the potentially broad applicability of electro-deformation (ED) for mechanical (visco-elastic) characterization of cells in suspension, we calculated electrical stresses acting on the cells and we fit strain data with a three-parameter “standard linear solid” (SLS) model of visco-elasticity. Morphological changes to the cells' cytoskeletons (CSK) were induced by exposure of U937 cells to CSK-disruptive toxins, and the effects on measured mechanical properties were compared with confocal fluorescence imaging of actin and vimentin in the cells.
2022-12-18T00:17:46.516Z
182,246,909
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2991/ICIHC-18.2019.17", "MAG": "2942053686", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The 2012 Indonesian Demographic Survey shows that the Maternal Mortality Rate is still high; this is also the case in Seluma District in 2015. Education disparities and regions are obstacles to access and quality of services received, so information technology is needed to facilitate the delivery of information to healthy individuals who do not regularly contact health services through the use of mobile phones. This study aims to determine the effect of Maternal Mobile Message (M3) on knowledge to antenatal care in pregnant women in Seluma District. The design of this study was quasiexperimental with the control group, an intervention in the form of an M3 program for pregnant women containing health promotion messages about pregnancy care. The samples were 60 pregnant women who were selected by purposive sampling. Data were analyzed with the Wilcoxon test. There was an effect of Maternal Mobile Message (M3) on knowledge (p= 0.00), and attitude (p= 0.00) to antenatal care in pregnant women in Seluma District. Keywords—Maternal Mobile Messages (M3), health promotion, pregnant women
2022-01-27T15:55:36.908Z
161,338,371
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.26457/mclidi.v1i0.66", "MAG": "1580984362", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Esta es una propuesta en donde se disena, aplica, evalua y analiza desde la postura del docente reflexivo la propuesta de intervencion educativa para la elaboracion del diseno de ambientes de aprendizajes ludicos como recurso para desarrollar los contenidos de los bloques del programa, disminuyendo asi las conductas disruptivas en alumnos de 2o grado de una Escuela Publica de nivel primaria. Se inicio con un diagnostico que permitiera ayudar a conocer las problematicas que pueden tener y enfrentar tanto los alumnos como la escuela. Se tomaron en cuenta tres dimensiones que deberia abarcar el diagnostico aulico segun Luchetti y Berlanda (1998) las cuales son: disposicion para aprender, conocimientos previos y niveles de desarrollo evolutivo. Se analizaron los resultados del diagnostico en cuatro ambitos: El ambito institucional de la Escuela Primaria Guadalupe Victoria no presento alguna complicacion para el proceso de ensenanza-aprendizaje de los alumnos. En cuanto al ambito pedagogico de la profesora tutora y de la estudiante normalista se puede observar que por parte de la estudiante normalista, hace falta el conocimiento de algunos contenidos de los Planes y Programas de la Educacion Basica. Respecto a la profesora tutora, se contempla una larga trayectoria con esos grados de primaria y tambien se percibe que sus clases no son innovadoras ni llamativas para los alumnos, lo cual si fue un aspecto importante y sobresaliente que se tomo en cuenta para la eleccion del tema. En el ambito academico, los alumnos presentaron bajas calificaciones en general en todas las asignaturas, lo cual dio pie a la eleccion de trabajar transversalmente con las asignaturas de Espanol, Matematicas, Exploracion de la Naturaleza y la Sociedad, Educacion Artistica y Formacion Civica y Etica. En cuanto al ambito sociocultural, se observo que la mayoria de los padres de familia no realizan actividades recreativas con sus hijos. La familia es un factor social importante ya que en este nucleo se establecen limites, reglas y actividades recreativas que cuando no son ensenadas ni practicadas en este ambito, el nino no tiene un parametro que seguir y se comporta de manera disruptiva en cualquier entorno social, incluyendo la escuela y el aula. La problematica del grupo fue la constante presentacion de conductas disruptivas dentro del aula. Se eligio esta problematica y no otra ya que el hecho de que presenten conductas disruptivas, trunca el proceso de aprendizaje de los alumnos. La propuesta se baso en juegos de feria, creando asi ambientes de aprendizaje ludicos que fueron el recurso que provoco excelentes resultados reflejados en la disminucion de conductas disruptivas de los alumnos de 2o grado de primaria.
2022-02-08T22:17:19.561Z
6,234,755
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/EEM.2015.7216759", "MAG": "1547792813", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Demand response programs have proven merits in facilitating power grid needs and dynamic market operation. The coordination of load flexibility is an intricate process in design and execution specifically in terms of the accessing market party, signaling program and release of flexibility to the system. This work takes a closer look at the complexity of aggregation in European power markets and concludes that there is a need for a more comprehensive framework than the ones proposed till date if demand response services are to be successfully implemented in the member states.
2022-08-27T06:03:54.353Z
168,395,680
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.5539/ENRR.V6N2P145", "MAG": "2414500445", "PubMedCentral": null }, "license": null, "status": null, "url": null }
While progress has been made for providing drinking water through the completion of the Millennium Development Goals and other international programs, millions of people still do not have access to clean drinking water. This study examines how drinking water coverage is impacted using three regime ownership models. Using the framework of the privately-owned, publicly-owned, and decentralized regime models, the impacts of water production, non-revenue water, and unit operation cost are evaluated for drinking water coverage. A sample of 144 utilities across 33 countries were sampled using data from the International Benchmarking Network for Water and Sanitation Utilities. Using ordinary least squares modeling, results indicate that predicting water coverage from water production, non-revenue water, and unit operational costs provided weak explanations of variation for both publicly-owned and decentralized regimes. None of the three regime models established a significant relationship between water coverage and all three independent variables. For publicly- and privately-owned water regimes, decreasing non-revenue water by plugging leaks and improving infrastructure can translate into higher rates of water coverage. For decentralized water regimes, higher levels of unit operational cost can increase water coverage. The regression analyses also showed that broad claims about regime ownership, efficiency, and improved water coverage should be suspect. None of the three regime models established a significant relationship between water coverage and all three independent variables. This suggests that the competing claims that privatized drinking water utilities as being more efficient or more able to provide water coverage as compared to other types of utilities in the literature is not supported when compared across countries.
2022-09-02T08:39:08.963Z
244,916,317
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1093/ofid/ofab466.064", "MAG": null, "PubMedCentral": "8643886" }, "license": "CCBY", "status": "GOLD", "url": "https://doi.org/10.1093/ofid/ofab466.064" }
Abstract Background There are a paucity of robust population PK (popPK) models to inform vancomycin (VAN) dosing in critically ill children. The majority of published models incorporate peak/trough data and rely on flawed estimates of renal function. We sought to develop a popPK model for IV VAN in critically ill children utilizing novel plasma and urinary biomarkers. Methods We conducted a prospective observational study of critically ill children prescribed VAN for a suspected infection in the CHOP pediatric ICU. Children < 1 year of age and those receiving ECMO or CRRT were excluded. Five VAN samples were collected from a single dosing interval for each subject. Plasma biomarkers (creatinine [Cr], cystatin C [CysC], NGAL) and urinary biomarkers (CysC, NGAL, KIM-1, osteopontin) were collected the morning of PK sampling; urinary biomarkers were corrected for urine creatinine. Nonparametric popPK modeling was performed using Pmetrics. The impact of renal function (GFR) on VAN clearance (CL) was estimated first, comparing model performance with each biomarker (Cr and plasma CysC). The influence of age, sex, additional biomarkers, PIM3 score, and receipt of vasopressors as covariates was then assessed for relevant PK parameters. Results 30 subjects completed the study. Median age was 10 years (range 1-17); 76% were male. The majority (90%) of children received VAN for suspected sepsis. PK sampling occurred at a median of 37.7 hours (range 24.6-94.8) into VAN treatment; 136 VAN samples were included. A 2-compartment model with fixed allometric scaling of 0.75 on clearances and 1 on volumes best described the data. CysC-based GFR as a covariate on VAN CL using the HOEK formula (GFR = -4.32 + (80.35/CysC)) resulted in the best model fit. Age and plasma NGAL were also informative on VAN CL in the final model (Figure 1). During model building, urinary NGAL was also associated with VAN CL (comparable to plasma NGAL) and outperformed Cr, although it was not retained in the final model. Figure 1. Final population PK model and parameter estimates. Conclusion Plasma CysC is a better renal function estimate than Cr to inform VAN clearance in critically ill children. Urinary and plasma NGAL also improved estimation of VAN CL during popPK modeling. Novel biomarkers can better describe VAN exposures in critically ill children than reliance on Cr alone. Disclosures Kevin J. Downes, MD, Merck (Individual(s) Involved: Self): Grant/Research Support Stuart L. Goldstein, MD, Bioporto (Consultant, Grant/Research Support)
2022-09-02T03:45:58.589Z
96,332,781
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/00103620903494384", "MAG": "2010339553", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Factory lime generated during sugar beet processing contains phosphorus (P). Factory lime collected from seven sugar beet factories in North Dakota and Minnesota had P concentrations ranging from 3470 to 7043 mg P kg−1. Soil collected from two field trials one and two growing seasons after factory lime application was analyzed for pH changes and soil‐test P (STP). At one site, soil pH increased after both growing seasons, as did STP, indicating a continued release of P as the factory lime dissolved and reacted with the soil. At the second site, increased soil pH and STP were evident after one growing season, but a few months later the pH had no further change and STP decreased. The data suggest factory lime has the potential to supply P to a growing crop, but actual proportion of P available from the factory lime could not be quantified from these experiments.
2022-09-07T04:16:05.794Z
85,670,459
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1002/AQC.3270050104", "MAG": "2167441985", "PubMedCentral": null }, "license": null, "status": null, "url": null }
1 Macroinvertebrate and Dipper Cinclus cinclus abundances and pH were assessed on four rivers in the south-central highlands of Scotland in early winter 1990 to examine the general applicability of Dipper/acidity relationships established during the breeding season (Ormerod et al., 1985; Vickery, 1991). 2 The most acid waters had the lowest invertebrate biomasses and Dipper densities. Birds on these rivers spent significantly more of the morning foraging and less time at rest, apparently reflecting reduced prey capture rates and hence the greater time required to replace overnight mass losses. 3 Analysis of published data on seasonal changes in Dipper population densities and individual energetic demands suggests that even accounting for the higher numbers of Dippers in all habitats during autumn and winter, energetic requirements both of individuals and populations are greatest during breeding, when the costs of self maintenance are coupled with the additional demands of chick rearing. 4 However, from the patterns found here and elsewhere during autumn it appears that the effects of acidity on Dipper populations are important generally during both the breeding and non-breeding seasons.
2022-09-12T10:39:30.173Z
232,479,689
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.33073/pjm-2021-001", "MAG": null, "PubMedCentral": "8008768" }, "license": "CCBYNCND", "status": "GOLD", "url": "https://sciendo.com/pdf/10.33073/pjm-2021-001" }
Abstract Short-term or acute temperature stress affect the immune responses and alters the gut microbiota of broilers, but the influences of long-term temperature stress on stress biomarkers and the intestinal microbiota remains largely unknown. Therefore, we examined the effect of three long-term ambient temperatures (high (HC), medium (MC), and low (LC) temperature groups) on the gene expression of broilers’ heat shock proteins (Hsps) and inflammation – related genes, as well as the caecal microbial composition. The results revealed that Hsp70 and Hsp90 levels in HC group significantly increased, and levels of Hsp70, Hsp90, IL-6, TNF-α, and NFKB1 in LC group were significantly higher than in MC group (p < 0.05). In comparison with the MC group, the proportion of Firmicutes increased in HC and LC groups, while that of Bacteroidetes decreased in LC group at phylum level (p < 0.05). At genus level, the proportion of Escherichia/Shigella, Phascolarctobacterium, Parabacteroides,and Enterococcus increased in HC group; the fraction of Faecalibacterium was higher in LC group; and the percentage of Barnesiella and Alistipes decreased in both HC and LC groups (p < 0.05). Functional analysis based on communities’ phylogenetic investigation revealed that the pathways involved in environmental information processing and metabolism were enriched in the HC group. Those involved in cellular processes and signaling, metabolism, and gene regulation were enriched in LC group. Hence, we conclude that the long-term temperature stress can greatly alter the intestinal microbial communities in broilers and may further affect the host’s immunity and health.
2022-09-30T01:24:18.630Z
247,440,139
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3389/fpubh.2022.855671", "MAG": null, "PubMedCentral": "8965038" }, "license": "CCBY", "status": "GOLD", "url": "https://www.frontiersin.org/articles/10.3389/fpubh.2022.855671/pdf" }
Healthy housing can set its occupants completely in good physical, mental and social conditions, but there is a lack of research in China on the public's willingness to pay (WTP) for healthy housing. From the perspective of cognitive psychology, this study constructs an analytical framework based on the model of “theory of planned behavior” (TPB), the theory of selective information exposure, and the model of “emotions as social information,” while exploring the effect mechanism of the online reviews on the public's WTP for healthy housing during COVID-19 pandemic. In combination with eye-tracking experiments and subjective reports, physiological, psychological and behavioral multimodal data on WTP of 65 participants for healthy housing are collected. Partial least squares structural equation modeling (PLS-SEM) is adopted to analyze the formation effect mechanism of the public's WTP for healthy housing. This study acquires the following results: (i) Information attentiveness to online reviews on different valence information of healthy housing as obtained in eye tracking experiments delivers significant effect on attitude, subjective norm (SN) and perceived behavioral control (PBC), but has no direct effect on the public's WTP for healthy housing; (ii) Hypotheses from TPB model are verified. attitude, PBC and SN can all make significant effect on WTP for healthy housing, with attitude showcasing the most prominent effect; and (iii) In terms of the mediating effect, information attentiveness can deliver significant indirect effect on WTP through attitude.
2022-12-10T05:02:01.730Z
45,776,519
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1097/IAE.0000000000001202", "MAG": "2484603400", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Purpose: To report the efficacy of photodynamic therapy (PDT) for management of choroidal nevus associated with subfoveal fluid. Methods: A retrospective chart review of 15 patients with choroidal nevus and associated subfoveal fluid treated with PDT was performed. Standard-fluence PDT was used in all patients and response to treatment was assessed with optical coherence tomography. Results: Complete resolution of subfoveal fluid was achieved in 9 eyes (60%) and partial resolution in 4 eyes (27%); 1 eye (7%) experienced worsening subfoveal fluid, and 1 eye (7%) was stable after PDT. After PDT, visual acuity improved in 8 eyes (53%), was stable in 6 (40%), and worsened in 1 eye (7%). Five patients (33%) required a second session of PDT with a median of 4 months (mean, 9 months; range 2–25 months) between the first and second sessions of PDT. Conclusion: Photodynamic therapy is a safe and effective treatment modality for choroidal nevus with subfoveal fluid. Photodynamic therapy provided satisfactory rates of resolution of subfoveal fluid in 87%, which was complete in 60% and partial in 27%. Further studies could further define the role and limitations of PDT for management of subfoveal fluid from choroidal nevus.
2022-12-15T17:59:58.449Z
205,039,259
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1056/NEJMc0706805", "MAG": "2001846079", "PubMedCentral": null }, "license": null, "status": null, "url": null }
In a woman with MRSA, recurrent deep abscesses resolved only after treatment of the family's MRSA-positive cat.
2022-12-18T09:06:04.343Z
177,783,794
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3406/SPGEO.1999.1213", "MAG": "2068328008", "PubMedCentral": null }, "license": null, "status": null, "url": null }
L'induration du niveau spatial mondial est un processus multiseculaire qui s'est considerablement accelere depuis une trentaine d'annees. Cette mondialite est donc un objet geographique et pose des problemes nouveaux a notre discipline. On peut analyser le Monde comme un geon qui serait sans equivalent de meme niveau et sans pouvoir etre transcende. Ainsi, systeme Monde et systeme Terre entrent en adequation et la configuration est differente de celle des autres systemes spatiaux. De plus, le bouclage, element clef de la mondialisation contemporaine, en fait un systeme spatial rond. Enfin, le developpement de lineaments d'une societe mondiale complexifie la substance de la mondialisation et autorise a penser le Monde comme un territoire. In fine reflechir du point de vue du Monde localise et relativise les decoupages du systeme des sciences sociales.
2022-12-31T15:28:50.535Z
202,051,795
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.22631/AJGC.2017.101557.1031", "MAG": "2779812947", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Quinolinium dichromate (QDC) and quinolinium chlorochromate (QCC) were studied as efficient reagents for electrophilic aromatic nitration using sodium nitrite and thiocyanation  by using ammonium thiocyanate under conventional, ultrasonic and solvent-free microwave assisted conditions. The microwave-assisted protocols exhibited remarkable rate acceleration and offered selective thiocyanation of the aromatic and heteroaromatic compounds with good yields. Addition of anionic (SDS) micelle to the reaction medium afforded considerable rate enhancements, while cationic (CTAB) and nonionic (Tx-100) micelles did not affect the rate noticeably. These protocols have were extended to regioselective thiocyanation of various aromatic compounds. Results were are completely similar to the nitration protocols. However, the reactions revealed comparatively shorter reaction times, and better yields in nitration reactions than in thiocyanation protocols. Catalytic effect of the SDS was attributed to the electrostatic stabilization of the cationic electrophile (NO2+ in nitration, and SCN+ in thiocyanation).
2022-01-27T07:17:13.180Z
109,659,315
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/OCEANS.1978.1151059", "MAG": "2009799817", "PubMedCentral": null }, "license": null, "status": null, "url": null }
In 1975, the NOAA Data Buoy Office (NDBO) began deploying a data acquisition system identified as the Prototype Environmental Buoy (PEB) payload on their operational buoys. This payload could report environmental data from remote ocean areas to shore through radio telemetry, but could only receive data inputs in the form of analog voltages. Digital data could not be accommodated. NDBO subsequently developed a wave measurement system specially designed to interface with the PEB payload. This Wave Spectrum Analyzer (WSA) system consisted of 12 parallel analog filters, each of which produced an output voltage related to the spectral density in the vicinity of the center frequency of the filter. Duplicates of this WSA system have since been deployed on a number of operational deep-ocean buoys and have produced wave data routinely.
2022-02-10T05:48:39.450Z
231,977,394
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/SCEMS48876.2020.9352265", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
The traditional ladder-type time-limited current protection for feeders generally has the problems of slow fault isolation speed, low accuracy and poor reliability. Depending on the protection of the communication channel, the fault can be isolated and recovered accurately, but its reliability and rapidity are limited by the communication channel, and the construction and maintenance cost of the channel is high. Channel-free protection, which does not depend on communication channel, has better protection characteristics, but it is difficult to give full play to its advantages when symmetry fault occurs. Especially with the access of wind power, photovoltaic and energy storage, the distribution network structure has become increasingly complex, which has changed from single power supply network to multi-power supply network, making the existing protection schemes more difficult to meet the actual needs. In view of this situation, this paper proposes a new high-speed self-healing automatic protection scheme for distribution network. This protection scheme does not need communication channel and channel equipment to transmit fault information to each protection unit, and has the characteristics of high reliability, accurate fault isolation and fast fault isolation.
2022-01-27T01:36:34.144Z
97,634,142
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1246/BCSJ.44.1506", "MAG": "2159540900", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Proton spin-lattice relaxation measurements were carried out on chloroform in carbon tetrachloride, benzene, pyridine, acetone, and dimethylsulfoxide (DMSO) in order to investigate the effect of the intermolecular interaction on the spin-lattice relaxation time, T1 of chloroform. It was found that the order of the effects of solvents on T1 is as follows: DMSO>acetone, pyridine>benzene, carbon tetrachloride; this order corresponds to that of the association constant of chloroform with these solvents. The T1 values of benzene and acetone were also determined on chloroform-benzene and chloroform-acetone mixtures. On the basis of the results obtained on these solutions together with the results on the T1 of chloroform in various solvents, we estimated the lifetimes of the chloroform-benzene complex and of the chloroform-acetone hydrogen-bonding complex. We tried to keep the proton-density constant throughout the solutions, in order to avoid an ambiguity arising from its change, by adopting the corresponding d...
2022-09-12T05:05:29.897Z
248,590,244
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1164/ajrccm-conference.2022.205.1_meetingabstracts.a5007", "MAG": null, "PubMedCentral": null }, "license": null, "status": "CLOSED", "url": null }
Asthma is a chronic airway inflammatory disease characterized by airway hyperreactivity (AHR) and eosinophilic airway inflammation. Dendritic cells (DCs) are essential for the development of asthma via presenting allergens, causing Th2 skewing and eosinophil inflammation. Recent studies have revealed that CD109, a glycosylphosphatidylinositol-anchored glycoprotein, is involved in the pathogenesis of inflammatory diseases such as rheumatoid arthritis and psoriasis. However, no study has addressed the role of CD109 in asthma. This study sought to address the role of CD109 on DCs in the development of AHR and allergic inflammation. CD109 deficient mice (CD109-/- mice) were sensitized with house dust mite (HDM) or ovalbumin and compared to wild-type (WT) mice for induction of AHR and allergic inflammation. CD109-deficient mice had reduced AHR and eosinophilic inflammation together with lower Th2 cytokine expression compared to WT mice. Interestingly, CD109 expression was induced in lung conventional DC2s (cDC2s), but not lung cDC1s, upon allergic challenge. Lung cDC2s from CD109-/- mice had a poor ability to induce cytokine production in ex vivo DC-T cell cocultures with high expression of RUNX3, resulting in suppression of Th2 differentiation. Adoptive transfer of bone-marrow-derived CD109-/- DCs loaded with HDM failed to develop AHR and eosinophilic inflammation. Finally, administration of monoclonal anti-CD109 antibody reduced airway eosinophils and significantly decreased AHR. Our results suggest the involvement of CD109 in asthma pathogenesis. CD109 is a novel therapeutic target for asthma.
2022-10-12T18:33:42.404Z
85,287,632
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.7872/crym.v35.iss3.2014.221", "MAG": "2074060196", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Abstract Climacocystis was a monotypic genus typified by C. borealis. During a continuous survey of poroid basidiomycetes over China, several specimens of a Climacocystis species were collected at high elevations in southwestern China. They deviated from the type species, C. borealis in several microscopic features, including larger and ellipsoid to subcilindrical basidiospores (6-8.8 × 3-4.2 µm versus 5-6.8 × 3.2-4 µm), smooth cystidia (incrusted in C. borealis) and regularly arranged contextual hyphae (interwoven in the type species). Furthermore, phylogenetic inferences based on a combined dataset of ITS, nLSU-rDNA and EF1&agr; regions revealed that our specimens and specimens of C. borealis formed two distinct lineages. We therefore concluded that our chinese collections represent a new species, described below as Climacocystis montana sp. nov. Illustrated descriptions of the two Climacocystis species are provided.
2022-08-28T09:50:28.789Z
1,629,849
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1207/S15327752JPA4202_2", "MAG": "1968619643", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The perception of feelings within the family of 9-13-year-old boys were studied. The purpose was to determine the sensitivity of the Family Relations Test (FRT) in discriminating between inpatients, outpatients, and normal controls. Both patient groups more frequently identified family members as sources of negative feelings than normal controls. Inpatients expressed more self-flattery and self-criticism and an absence of a reciprocal, positive relationship with their fathers. The FRT is only able to make a few quantitative differentiations between a clinical and a normal sample of boys but certain qualitative aspects of the responses were particularly noteworthy.
2022-09-11T23:15:11.248Z
221,031,181
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1182/BLOOD.V110.11.2581.2581", "MAG": "2585423097", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Background: 4-HPR is a cytotoxic retinoid with broad anti-cancer activity in preclinical studies, but oral capsule 4-HPR had limited bioavailability and activity in clinical trials. An intravenous intralipid emulsion formulation of 4-HPR (ILE 4-HPR) was developed to increase 4-HPR systemic exposure. Methods: ILE 4-HPR was administered as a continuous intravenous infusion for 5 of every 21 days and systemic toxicities, clinical response, and pharmacokinetics (PK) assessed. Simon design dose escalation proceeded with a 100% increase per dose level until moderate toxicity in 2 patients or 1 dose-limiting toxicity (DLT). Ten dose levels were planned starting at 80 mg/m 2 /day, increasing until 1810 mg/m 2 . Plasma 4-HPR levels were measured by high performance liquid chromatography. Results: To date, 17 patients have been enrolled. At dose level 10 (1810 mg/m 2 /day), 2 patients experienced a DLT of grade 4 hypertriglyceridemia, 1 patient with transient grade 2 pancreatitis. A de-escalation to dose level 9 (1280 mg/m 2 /day) enrolled 5 patients: 1 had asymptomatic Grade 4 hypertriglyceridemia, 1 patient experienced pleural effusions that resolved after pleurocentesis. A de-escalation to dose level 8 (905 mg/m 2 /day) enrolled 5 pts: two patients experienced asymptomatic Grade 4 hypertriglyceridemias that resolved after stopping the infusion; enrollment is ongoing. PK showed a linear relationship of dose to plasma level, with steady-state 4-HPR levels of 25 μM (640 mg/m 2 , level 7); 54 μM (1280 mg/m 2 , level 9) and 62 μM (1810 mg/m 2 , level 10). Responses to date include a transient response in a non-Hodgkins lymphoma at 320 mg/m 2 , in two angioimmunoblastic T-cell lymphomas, an 8-month partial response at 1810 mg/m 2 /day and a 4+ month unconfirmed complete response at 905 mg/m 2 /day, and in a histone deacetylase inhibitor-refractory cutaneous T cell lymphoma, a 10+ month molecular complete response at 1280 mg/m 2 . All patients were heavily pretreated. The DLT of hypertriglyceridemia is likely related to the intralipid formulation vehicle accounting for 5/6 DLTs observed, all reversible. Conclusions: ILE 4-HPR can be safely administered and obtained 4-HPR plasma levels 6 to 7 times higher than previously obtained by oral capsule 4-HPR. Durable clinical activity was observed in T cell lymphomas in the dose range 905–1810 mg/m 2 . Supported in part by NCI U01CA62505 and the NCI RAID program.
2022-09-15T22:49:58.388Z
214,712,343
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.7150/ijms.43030", "MAG": "3016091350", "PubMedCentral": "7163361" }, "license": "CCBYNC", "status": "GOLD", "url": "https://www.medsci.org/v17p0931.pdf" }
Objective: High-risk human papillomavirus (HPV) E6 and E7 proteins are the major oncoproteins involved in the tumorigenesis of cervical cancer. The long control region (LCR) in HPV plays an important role in regulating the expression of the E6 and E7 oncogenes. In the current study, we investigated the association of HPV16 LCR variations with cervical cancer. Methods: A total of 139 HPV16-positive cervical cancer patients (case group) and 116 HPV16-positive asymptomatic individuals (control group) were enrolled in the current study. Then, the HPV16 LCR was sequenced to determine the association between LCR variations and cervical cancer. Results: In the current study, HPV16 A1-A3 (19.4%), A4 (78.4%) and D3 (2.2%) variants were found in the case group. However, only A1-A3 (34.5%) and A4 variants (65.5%) were found in the control group. The distribution of the HPV16 variants between the case and control groups was significantly different (P=0.009). Moreover, a total of eleven variations (A7167G, A7173C, C7176T, C7200T, T7269C, C7286A, C7729A, C7763T, A7841G, G7867A and T24C) were significantly different between the case and control groups (P<0.05). For the sub-lineage analysis, only C7873G variations were significantly different between the case and control groups in the A4 (As) variant (P=0.039). Conclusion: Our results showed that specific variations in the HPV16 LCR were associated with cervical cancer. Our study will provide a good reference for further understanding of the relationship between HPV16 LCR variation and cervical cancer.
2022-12-10T07:35:47.590Z
238,814,310
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1111/mec.16269", "MAG": "3195350019", "PubMedCentral": "9299253" }, "license": "CCBY", "status": "HYBRID", "url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/mec.16269" }
Adaptation to derived habitats often occurs from standing genetic variation. The maintenance within ancestral populations of genetic variants favourable in derived habitats is commonly ascribed to long‐term antagonism between purifying selection and gene flow resulting from hybridization across habitats. A largely unexplored alternative idea based on quantitative genetic models of polygenic adaptation is that variants favoured in derived habitats are neutral in ancestral populations when their frequency is relatively low. To explore the latter, we first identify genetic variants important to the adaptation of threespine stickleback fish (Gasterosteus aculeatus) to a rare derived habitat—nutrient‐depleted acidic lakes—based on whole‐genome sequence data. Sequencing marine stickleback from six locations across the Atlantic Ocean then allows us to infer that the frequency of these derived variants in the ancestral habitat is unrelated to the likely opportunity for gene flow of these variants from acidic‐adapted populations. This result is consistent with the selective neutrality of derived variants within the ancestor. Our study thus supports an underappreciated explanation for the maintenance of standing genetic variation, and calls for a better understanding of the fitness consequences of adaptive variation across habitats and genomic backgrounds.
2022-12-19T20:43:31.165Z
201,846,528
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1097/QAD.0000000000002296", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
OBJECTIVES To evaluate the effects of cannabis and/or cocaine use on inflammatory, oxidative stress status and circulating monocyte subsets in HIV-infected individuals under antiretroviral therapy. DESIGN Soluble CD14 (sCD14), intestinal fatty acid-binding protein (IFABP), tumor necrosis factor-alpha (TNF-α), interleukin (IL)-6, IL-8, IL-10, C-reactive protein (CRP) and oxidative stress markers were examined. The monocyte subsets and their activation and cytokine production by peripheral blood mononuclear cells (PBMCs) of HIV-1 infected individuals upon lipopolysaccharide (LPS)-stimulation were also investigated. METHODS sCD14, IFABP, TNF-α, IL-6, IL-8 and IL-10 levels were evaluated using ELISA, CRP by turbidimetry; lipid peroxidation (TBARS) spectrofluometrically and total thiol levels by using 5-5'-dithio-bis (2-nitrobenzoic acid) reagent. Monocyte subsets and activation were assessed by flow cytometry. RESULTS All HIV-infected drug user groups showed higher sCD14 levels compared with HIV+ nondrug users. IFABP was increased in HIV+ drug-users in relation to healthy individuals. Cannabis use lowered the percentages of inflammatory, nonclassical, activated-classic and activated-inflammatory monocytes. Cocaine users showed increased plasmatic TNF-α and TBARS levels, decreased thiols content and lower activated-classic and inflammatory-monocyte percentages. Cannabis-plus-cocaine use increased CRP, IL-8 and IL-6/IL-10 ratio, but decreased thiol content, and inflammatory and activated-classic monocyte percentages. PBMCs of cannabis and cannabis-plus-cocaine users showed low-potential cytokine production either spontaneously or under LPS-stimulation. CONCLUSION In HIV infection, the use of cannabis induces predominantly an anti-inflammatory profile. The use of cocaine and cannabis-plus-cocaine showed a mixed pro-inflammatory and anti-inflammatory profile, with predominance of inflammatory status. Further studies are required to better understand the action of these drugs in HIV infection.
2022-12-27T14:47:59.554Z
85,983,939
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/00219266.2000.9655701", "MAG": "2122409519", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Educators are beginning to recognise the importance and benefits of introducing pupils to biodiversity and associated issues. Generic criteria for successfully planning and developing a skills-based resource for biodiversity education are described. Implementation of the criteria are illustrated with reference to an Anglo- Bulgarian biodiversity education project.
2023-01-01T19:45:07.595Z
145,929,003
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1049/MNL.2019.0063", "MAG": "2936042351", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The monodisperse Fe@SiO2 core-shell nanocapsules were synthesised via hydrothermal reaction followed with heat treatment. Nanostructures were characterised by X-ray diffraction, scanning electron microscopy and transmission electron microscopy. The magnetic properties of Fe@SiO2 nanocapsules were evaluated with magnetic property measurement system. The results show that Fe@SiO2 core-shell nanocapsules are highly monodispersed. The silica thickness of Fe@SiO2 nanocapsules increased from 10–20 to 25–35 nm with increasing tetraethyl orthosilicate (TEOS) amount. In the Fe@SiO2 nanocapsules prepared with 900 μl TEOS, as the reaction temperature increases, the mean particle size of Fe@SiO2 nanocapsules increases from 328 to 546 nm. It is remarkable that the saturation magnetisation of Fe@SiO2 nanocapsules decreases with increasing silica thickness. However, the coercivity of nanocapsules has less influence with the variation of silica thickness and particles’ length.
2022-08-13T08:06:45.018Z
143,318,708
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.6251/BEP.19790601.14", "MAG": "2277688559", "PubMedCentral": null }, "license": null, "status": null, "url": null }
本研究目的在探討親子關係對於國民教育階段中兒童及青少年人格發展之影響,研究受試爲2084名國小一年級至國中三年級學生,各年級受試分別接受親子關係問卷,自我概念及內外控信念量表,此外,國小四年級至國中三年級受試尚接受情緒穩定性量表,國中一年級至國中三年級受試尚接受青年人格量表,國小一年級與四年級以及四中一年級受試尚就問題行爲接受教師之評定,全部所得資料經積差相關及多元迴歸處理分析之後,主要結果如下: 1.親子關係可有意義的可預測兒童及青少年自我概念,內控信念及情緒穩定等人格特質之發展。 2.在各項親子關係當中,父母之愛護、獎勵、拒絕及懲罰等變項對於兒童及青少年人格發展之影響,顯較父母之寬鬆、命令等變項爲大。 3.親子關係對於國小中高年級兒童以及國中階段青少年人格發展的影響,顯較國小低年級學生爲大。 4.父子關係與母子關係對於兒童及青少年人格發展具有同樣重要之影響。
2022-09-01T06:04:10.946Z
140,383,060
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/02796015.2000.12086001", "MAG": "10444926", "PubMedCentral": null }, "license": null, "status": null, "url": null }
I considered developing this legend as a story of’a school psychologist growing an identity through time and testing that identity in many different contexts, or as a description of my observations of school psychology over time. But these linear story lines read like a paper on the role of the school psychologist or one on the history of school psychology. Instead, the legend should has six short stories about school psychology, each with at least one moral to guide the future. I don’t have catchy titles for the stories but I have named them: Becoming a School Psychologist; Gaining a Statewide Perspective on School Psychology; Shaping School Psychology from Organizational and Political Platforms; Challenging Conceptual and Professional Growth-The Years at UC Berkeley; Promoting School Psychology on the National Political Scene; and, Forecasting a Future for School Psychology-Back to the Future. Throughout the stories, the main character is a school psychologist who attempts to promote the academic, personal, and social development of the school-age population from whatever work perspective she is engaged. To accomplish this mission, assessments and interventions and consultation and collaboration with education professionals, are expected to promote a psychological perspective in schooling that will enhance educators’ knowledge and plans for the education of children and adolescents for whom they have responsibility.
2022-09-13T15:54:16.678Z
247,797,162
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/iEECON53204.2022.9741608", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
This work provides the synthesis of multifunction biquad active filter which has three input voltage nodes and single output current node. The synthesis procedure which is based on the RLC parallel circuit is given step by step. An analog active building block employed in this synthesis is the modified current controlled current conveyor transconductance amplifier (M-CCCCTA). The proposed filtering structure consists of two M-CCCCTAs and two grounded capacitors without any passive resistors. All input voltage nodes and output current node are high impedance which is cascadable without the need of any buffer devices. Five second order filtering types are obtained in the network. The filtering parameters including the natural frequency (ω0), quality factor (Q) and pass band gain are electronically controlled. In addition, the Q is also electronically controlled without disturbing the ω0. The PSpice simulations using the model process parameters of the NR100N (NPN) and PR100N (PNP) bipolar transistor arrays ALA400CBIC-R from AT&T are given to investigate the characteristics of the proposed active filter.
2022-09-30T07:56:23.551Z
53,731,283
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1111/and.13175", "MAG": "2902409401", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The purpose of this study was to compare the clinical outcome of testicular spermatozoon versus ejaculated spermatozoon in the treatment of infertile males with high sperm DNA damage, referred as sperm DNA fragmentation index (DFI), that attending intracytoplasmic sperm injection (ICSI) programme in terms of clinical pregnancy, births delivered as the primary and pregnancy loss and embryo fertilisation as the secondary outcome. A total of 102 males fulfilling the inclusion criteria were enrolled in the present study. Of the 102 males, 61 infertile males underwent testicular spermatozoon combined with ICSI while the remaining 41 males applied ejaculated spermatozoa in their first ICSI cycles, and the data of them were collected and analysed. In a 18‐month follow‐up, testicular spermatozoon achieved higher pregnancy rate and deliver rate than those in ejaculated sperm group (pregnancy rate, 36% vs. 14.6%, p = 0.017; deliver rate, 38.5% vs. 9.8%, p = 0.001). Nevertheless, there were no significant differences in the number of oocytes aspirated and number of embryos transferred between the two groups. Additionally, the fertilisation rate in the testicular sperm study cohort (70.4%) was also similar to that in the ejaculated sperm group (75.0%). Based on the current data, we conclude that testicular spermatozoon is the prior option in the treatment of infertile males with high sperm DFI in ICSI programme. More high‐quality studies with larger samples size are needed in the future due to the relative small size and the nonrandomized design of the present study.
2022-10-25T14:23:45.851Z
7,213,254
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1046/j.1365-2893.2002.00373.x", "MAG": "2048555465", "PubMedCentral": null }, "license": null, "status": null, "url": null }
summary. The immune response to hepatitis C virus (HCV) is believed to be critical in determining the outcome of the disease. In this study we have analysed epitope recognition, cytokine profile, and anti‐HCV antibody responses in chronically HCV‐infected and recovered chimpanzees. Quantitative measurement of anti‐HCV antibody in HCV‐infected chimpanzees revealed that the response in HCV‐ recovered chimpanzees peaked within 4–20 weeks. In contrast, the anti‐HCV antibody responses in chronically HCV infected chimpanzees did not peak until 100–200 weeks after infection, and decreased gradually thereafter. T cell proliferation assays measuring responses to pooled HCV proteins revealed significant increases in the 3H‐uptake during the early stages of infection in recovered chimpanzees in comparison to the chronically infected ones. Class I‐restricted epitopes of the core, and NS3 proteins of HCV were analysed using 9–10 mer overlapping peptides covering the core and NS3 proteins, and IFN‐γ ELISPOT technique. Our data indicated early and broad class‐I restricted core, and NS3 protein epitope recognitions in HCV‐recovered chimpanzees but not in chimpanzees that had been chronically infected. Additionally, dominant epitopes recognized early in infection (8 weeks) were no longer recognized later in infection (followed up to 64 weeks). Cytokines profiling revealed a 50‐fold increase in TNF‐α secretion in the supernatant of core‐specific CD8 memory cells of the chronically infected chimpanzees in comparison to the recovered ones. In summary, multiple parameters correlate with HCV recovery in chimpanzees.
2022-12-10T03:56:53.040Z
6,145,250
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/ICCDA.2010.5541063", "MAG": "2044580519", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Flatness prediction model is one of the important techniques in flatness control system of high precision. In this paper, the nonlinear wavelet denoising method is used to filter the noise of the measure data availably. Then the filtered data are applied to recognize the flatness through the model based on multiple linear regression. The prediction model of symmetrical and asymmetrical coefficients can be obtained. The combination of wavelet transform and multiple linear regression can improve precision. The simulation results exhibit the effectiveness of our method.
2022-12-14T02:45:03.969Z