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149,893,038
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.21831/DINAMIKA.V3I2.21402", "MAG": "2898670265", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The aims of the study are to find out the influence of the following factors to the occupational health and safety (OHS) implementation perception: knowledge, attitude, working environment conditions, and all the three factors together. This research used the ex-post facto method. The population is 95 students. Data were collected using tests, questionnaire, and observation. Data were analyzed using regression analysis. The results show these following influences to the OHS implementation perception:  knowledge 5.6%, attitude 7%, and working environment conditions 8.3%. The combined knowledge, attitude, and working environment conditions have influenced the OHS implementation perception by 15.2%.Penelitian ini bertujuan untuk mengetahui pengaruh pengetahuan terhadap persepsi penerapan keselamatan dan kesehatan kerja, pengaruh sikap, kondisi lingkungan kerja, pengetahuan terhadap persepsi penerapan K3. Penelitian ini menggunakan metode ex- post facto. Populasi penelitian ini berjumlah 95 siswa. Teknik pengumpulan data menggunakan tes, kuesioner dan observasi. Teknik analisis data menggunakan analisis regresi. Hasil penelitian menunjukkan pengetahuan berpengaruh terhadap persepsi penerapan K3 sebesar 5,6%. Sikap berpengaruh positif terhadap persepsi penerapan K3 sebesar 7%. Kondisi lingkungan kerja berpengaruh positif terhadap persepsi penerapan K3 sebesar 8,3%. Pengetahuan, sikap dan kondisi lingkungan kerja secara bersama- sama berpengaruh terhadap persepsi penerapan K3 sebesar 15,2%.
2022-12-19T06:20:46.248Z
123,705,544
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1142/0845", "MAG": "2109267450", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This is an introductory book on Henstock integration, otherwise known as generalized Riemann integral. It is self-contained and introductory. The author has included a series of convergence theorems for the integral, previously not available. In this book, he has also developed a technique of proof required to present the new as well as the classical results.
2022-12-21T04:05:36.326Z
143,305,370
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/14999013.2011.625591", "MAG": "1970492534", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Deinstitutionalization, changes in both criminal and civil law, and the use of the criminal justice system to manage problematic behavior by individuals with serious mental illnesses have affected the number of people entering forensic mental health systems. This review examines data revealing trends in demand for forensic services in Canada, the United States, and internationally. The number of beds and resources allocated to forensic mental health services has steadily increased not only in Canada, but in other countries across the world. In Canada, the number of new accused entering the system doubled annually from 1992 to 2004. In the United States, the number of individuals found not guilty by reason of insanity (NGRI), forensic beds and forensic expenditures have all increased dramatically in recent years. Furthermore, countries in Western Europe – Austria, Denmark, England, Germany, Ireland, Italy, the Netherlands, Spain and Switzerland – have reported an increase of 110%, on average, in the number of forensic beds between 1990 and 2006. These increases have implications for both forensic and non-forensic mental health services. Suggestions to reduce forensic demand and increase the successful reintegration of forensic clients into the community are discussed.
2022-12-23T21:37:02.040Z
1,374,260
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2139/ssrn.2993108", "MAG": "2149928783", "PubMedCentral": null }, "license": null, "status": "GREEN", "url": "http://www.ifn.se/wfiles/wp/wp1054.pdf" }
This paper examines policy measures that foster the creation of innovations with high inherent potential and that simultaneously provide the right incentives for individuals to create and expand firms that disseminate such innovations in the form of highly valued products. In so doing, we suggest an innovation policy framework based on two pillars: (i) the accumulation, investment, and upgrading of knowledge and (ii) the implementation of mechanisms that enable knowledge to be exploited such that growth and societal prosperity are encouraged. Knowledge is a necessary but far from sufficient condition for growth. To secure industrial dynamics and growth in the long term, institutions must be designed both to encourage sophisticated knowledge investments and to stimulate the creation, diffusion and productive use of knowledge in all sectors of the economy. We argue that the latter area has been overlooked in the policy discussion and that a coherent innovation policy framework must include tax policy, labor market regulation, savings channeling, competition policy, housing market regulation, and infrastructure to foster growth and future prosperity.
2022-12-24T20:57:23.078Z
13,094,155
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/ITWKSPS.2010.5503212", "MAG": "1983209383", "PubMedCentral": null }, "license": null, "status": null, "url": null }
ALOHA was originally designed for communication between remote terminals and a central computer in Hawaii. For some time, however, multi-channel ALOHA, wherein randomized channel selection replaces randomized retransmission delay upon collision, has been used in settings such as online transaction processing via geostationary satellites. There, the long propagation delay renders channel sensing impractical, and the short messages render reservation schemes useless. For these applications, striving to maximize attainable throughput while meeting a deadline with near certainty captures both the service provider's fixed costs and per-transaction revenue, the user's delay consciousness, and ALOHA's probabilistic nature. This paper reviews several techniques that we have developed for this purpose. Their common theme is devoting a large amount of channel resources to a message before allowing it to fail to meet the deadline, while keeping a low mean per-message resource expenditure. This is achieved by assigning higher priority to messages in their later retransmission attempts. The performance improvement over naive schemes is dramatic, at times approaching the attainable unconstrained throughput. Finally, the schemes are practical.
2022-12-26T20:28:26.442Z
27,573,011
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1590/S1980-65742015000400005", "MAG": "2396465892", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Este estudio comparo la pontuacion total y las puntuaciones aisladas de los dominios de actividad fisica evaluados a traves de cuatro variaciones del IPAQ version larga: (a) semana tipica, administrado por un entrevistador; (b) semana tipica, autoadministrado; (c) ultimos siete dias, entrevistador; (d) ultimos siete dias, autoadministrado. La muestra incluyo a 38 estudiantes universitarios de educacion fisica. Puntajes de auto-reporte eran, en general, dos veces mas alto que entrevista, sin tener en cuenta el periodo de recuerdo. En cuanto a las puntuaciones de los dominios aislados, las puntuaciones de actividad fisica en el trabajo generados por su propio informe eran 6-7 veces mayores que las originadas a partir de entrevistas. Se observo la misma tendencia para la actividad fisica de los hogares. Las puntuaciones de actividad fisica de transporte no cambiaron de acuerdo con el modo de administracion. En terminos de actividad fisica en el tiempo libre, las puntuaciones fueron similares a excepcion de los ultimos siete dias administrado por entrevistador, que eran inferiores a los otros tres. En conclusion, puntuaciones mas altas se obtienen a traves del auto-informe, en comparacion con las entrevistas, probablemente por la mala interpretacion del instrumento en el modo de auto-informe. El periodo de recuerdo tuvo poco efecto sobre las estimaciones de actividad fisica.
2022-12-30T01:05:30.272Z
110,812,524
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.4028/www.scientific.net/AMR.694-697.3684", "MAG": "2073711030", "PubMedCentral": null }, "license": null, "status": null, "url": null }
In the new education and technology era, there are many challenges in enhancing the effectiveness of teaching and learning process for traditional engineering education in the field of welding. Innovative educational methods of welding teaching, training and research are proposed in order to provide high quality education with improved efficiency and minimal cost. Integrated teaching with effective combination of multimedia teaching, computer simulation technology and distance learning is investigated. The great advantage of virtual training is analyzed. Innovative welding research that encourages students’ creative thinking and innovative ideas is fully illustrated. Innovative welding educational methods introduced play a significant role in cultivating the qualified welding professionals.
2022-01-27T10:28:29.687Z
93,948,972
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1039/TF9454100081", "MAG": "1988727086", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Abstract The facts relating to the calender effected are briefly stated and illustrated by experimental data obtained with calendered plasticized polyvinyl chloride sheet. The nature of rubberlike deformation is outlined. A theory of the calender effect is proposed in terms of a mechanical model whose relation to molecular structure is indicated. The theory postulates that temperature-dependent yield values be associated with the mechanisms of high elastic deformation and plastic flow.
2022-02-10T16:38:15.491Z
92,812,120
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.4038/CJS.V48I1.7586", "MAG": "2921772613", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Recently, the suitability of using natural rubber (NR) in place of expensive, toxic polymers to prepare polymer electrolytes has been suggested. So far, according to available reports, no attention has been given to employ Sri Lankan NR for this purpose. This study is based on optimization and characterization of a NR based electrolyte and evaluation its suitability for a Mg rechargeable cell. The optimized composition, 63 MG49 Natural Rubber : 27 Mg(CF 3 SO 3 ) 2 ) : 10 EC (by weight basis) exhibits a conductivity of 2.83 x 10 -4 Scm -1 at room temperature. The electrolyte is purely an ionic conductor having a negligible electronic conductivity. Rechargeable cells are fabricated with configuration, Mg / NR based electrolyte / natural graphite. Open circuit voltage of the cell is 1.5 V which may motivate the intention of researchers. The value is quite suitable for low power requirements. Electrochemical Impedance Spectroscopy as well as Cyclic Voltammetry tests prove the absence of any parasitic reactions in the cells. Constant load discharge test results confirm a discharge capacity of 5.32 x 10 -3 Ahg -1 . Results prove the candidacy of NR as well as graphite to be used for cells with several highlights.
2022-02-10T18:04:43.923Z
43,821,349
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/CLEOPR.2015.7376020", "MAG": "2247814779", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Conventional quantum key distribution (QKD) schemes determine the amount of leaked information through estimation of signal disturbance. Here we present a QKD protocol based on an entirely different principle, which works without monitoring the disturbance.
2022-02-12T01:47:41.019Z
248,107,024
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.22184/1993-8578.2022.15.1.20.27", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
Представлены результаты исследования десорбции газа с внутренних поверхностей и диффузии из толщи деталей сверхвысокочастотных электровакуумных приборов за счет одновременного термического и ультразвукового воздействия на корпус прибора. Приведены сравнения парциальных и общих давлений при различных условиях откачки. Дано физическое объяснение механизма ультразвукового активирования процессов диффузии и десорбции газовых компонентов в вакууме.
2022-04-13T15:57:35.414Z
69,488,453
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1177/026839629000500113", "MAG": "2905781243", "PubMedCentral": null }, "license": null, "status": null, "url": null }
underlying premise is that: 'the impact of 1992 on the elements of a corporate business plan will mean a greater reliance on information technology reaching all the dimensions of the strategy. IT will only yield sustainable competitive advantage ifit is used solely to reach targeted, focused business objectives.' The major strength of the book is that it succeeds in grounding the discussion of IT issues in the wider problems of Britain's entry into the single European market. Parts one and two provide a competent introduction to 'The 1992 opportunity' and 'The IT challenge'. The emphasis throughout is on the sheer scale of the changes envisaged: 'in one single process, UK management will have to redirect its focus towards half a dozen major markets, learn how to compete in numerous languages and cultures, deliver products and services that offer sustainable competitive advantage, lock in existing domestic customers ... adopt a viable reliance on IT, continue to motivate staff, and most vitally, continue to trade profitably. In part three ('Making IT happen in Europe') the authors address themselves to the task of establishing ground rules for management of IT projects across national boundaries. Here again the emphasis is on the scale and complexity of the industrial risorgimento in the modern European corporation. The fundamental message is that successful IT requires large scale organizational change, and that 'even without a multicountry dimension more projects fail because of organizational problems and management environment problems than for any other cause'. Sensible advice is provided on the need to manage expectations at all levels. The treatment of the technical and organizational change process is mildly pluralist in orientation but the authors seem unsure as to how far they want to go down the pluralist road, and they misunderstand the contribution of organization theory when they describe this as 'a well established set of principles which can be applied to any situation in which change occurs.' This leads to some confusion as to the exact nature of the change processes described, and the relationship between IT and organizational change. The introduction states that IT 'will run parallel with the companies efforts to service its customers and expand its position in the marketplace. So prominent will be the role of IT in achieving this 1992 strategy that some may be forgiven for assuming that the technology was the plan itself; and yet information technology appears (on page 157) as the 'very fabric of the company'. In the section on project management it is asserted that the use of a management plan in implementation will 'resolve conflicts and confusion before the project starts and throughout its duration'. This sits uneasily with earlier assertions about the implementation of IT projects being managed 'with surgical precision'. As an introduction to the main issues the book serves its purpose very well but underestimates Book reviews 55
2022-08-20T13:30:02.610Z
62,565,972
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1049/IP-VIS:20010109", "MAG": "2021046462", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The operational capacity of a watermark data channel is deduced by examining the correlation distribution at the retrieval end of a spread-spectrum-based watermarking system. This enables capacity to be determined given MPEG-2 compression, geometric attack, visual thresholds and channel coding. Watermarking itself is carried out in the DCT domain using video-dependent and visual perception concepts. An objective of the paper is to determine the capacity improvement provided by advanced FEC. It is found that FEC based on multiple parallel concatenated convolutional codes (3PCCCs) can give an order improvement in capacity for compressed video, and typically gives 0.5 kbit/s capacity under a combined compression-geometric attack.
2022-09-13T12:42:03.944Z
235,337,820
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3389/fonc.2021.673147", "MAG": null, "PubMedCentral": "8212704" }, "license": "CCBY", "status": "GOLD", "url": "https://www.frontiersin.org/articles/10.3389/fonc.2021.673147/pdf" }
Study Registration https://www.drks.de/drks_web/navigate.do?navigationId=trial.HTML&TRIAL_ID=DRKS00022837,DRKS00022837. Background Intensified oncological treatment for advanced cancer patients at the end-of-life has been specified as aggressiveness of care (AOC) and increased over the past decades. The aims of this study were to 1) determine the frequency of AOC in Central Europe, and 2) investigate differences in mental health outcomes in bereaved caregivers depending on whether the decedent had experienced AOC or not. Materials and methods We conducted a cross-sectional study in a large tertiary comprehensive cancer care center in Germany. Bereaved caregivers provided information about (a) treatment within the last month of life of the deceased cancer patient and (b) their own mental health status, i.e., decision regret, complicated grief, depression, and anxiety. After multiple imputation of missing data, differences in mental health outcomes between AOC-caregivers and non-AOC-caregivers were analyzed in a multivariate analysis of variances. Results We enrolled 298 bereaved caregivers of deceased cancer patients. AOC occurred in 30.9% of all patients. In their last month of life, 20.0% of all patients started a new chemotherapy regimen, and 13.8% received ICU-treatment. We found differences in mental health outcomes between bereaved AOC- and non-AOC-caregivers. Bereaved AOC caregivers experienced significantly more decision regret compared to non-AOC caregivers (Cohen’s d = 0.49, 95% CI [0.23, 0.76]). Conclusion AOC occurs frequently in European health care and is associated with poorer mental health outcomes in bereaved caregivers. Future cohort studies should substantiate these findings and explore specific trajectories related to AOC. Notwithstanding, shared-decision making at end-of-life should increasingly account for both patients’ and caregivers’ preferences.
2022-09-26T16:03:32.677Z
54,436,424
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2514/6.2018-4980", "MAG": "2819312374", "PubMedCentral": null }, "license": null, "status": null, "url": null }
In the background of the development of More Electric Aircraft (MEA) framework, weight-optimized design of an aircraft's electric power system is essential. Power electronics systems have played an important role in the on board power distribution system. However, the difficulties in its design variable identification and the design interaction decoupling process have been primary obstacles to design the electric power system in an optimized and efficient manner. In this paper, a hierarchical weight optimization design procedure has been applied to solve this problem. To accelerate the design iterations, metaheuristic optimization methods, such as genetic algorithm (GA), particle swarm optimization (PSO), and simulated annealing (SA) are considered due to the nonlinear and discrete nature of power electronics converters. Finally, a design example of a 2 kW voltage source inverter (VSI) is shown to illustrate the hierarchical optimization design process using metaheuristic optimization methods.
2022-09-29T23:13:31.309Z
156,234,291
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1142/q0056", "MAG": "2495302407", "PubMedCentral": null }, "license": null, "status": null, "url": null }
In 1991 South Korea, along with North Korea, was made an official member of the UN. Using international relations theory, this book begins by looking at the struggle and eventual impact of the memb ...
2022-10-02T15:56:14.399Z
199,436,366
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3760/cma.j.issn.1002-0098.2019.08.004", "MAG": "3024248600", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Objective: To evaluate the mandibular condylar location and morphology in the temporomandibular joint disorders. Methods: One hundred thirty-seven TMD patients (age 37.5±16.1 years, male/female=39/98) were performed with MRI scan for temporomandibular joint (TMJ) from November, 2011 to April, 2019 in Department of Radiology,Hainan Hospital of General Hospital of Chinese PLA and General Hospital of Chinese PLA. The patients were classified into 3 groups according the disc displacement: disc without displacement (DWoD) (185 TMJ), disc displacement with reduction (DDWR) (17 TMJ) and disc displacement without reduction (DDWoR) (72 TMJ). The location (anterior position, central position and posterior position) and morphology (oval shape, flat shape and beaklike shape) of the condylar head were observed on the sagittal PDWI, and the long and short axes were measured on the axial T2WI. Another groups were classified into 3 subgroups according to the disc displacement of bilateral TMJ: bilateral normal disc location (biND) (74 cases), unilateral disc displacement (uniDD) (40 cases) and bilateral disc displacement (23 cases). The inter-condyle angle was measured on the axial T2WI. Results: There was no significant difference for the location of condylar head among DWoD, DDWR and DDwoR groups (χ(2)=7.435, P=0.115). The rate for flat condylar shape was significantly higher in DWoD group [83.9%(115/137)] than that in DDWoR group [50.7%(34/67)], and the rate for beaklike condylar shape was significantly lower in DWoD group [16.1%(22/137)] than that in DDWoR group [49.3%(33/67)] (χ(2)=23.521, P<0.001). The length of long axis presented significantly longer in DWoD group [(17.2±2.4) mm] than that in DDWR group [(15.4±2.0) mm] and that in DDWoR group [(14.7±2.7) mm] (P<0.05). The length of short axis presented significantly longer in DWoD group [(7.3±1.2) mm] than that in DDWR group [(6.5±1.3) mm] and that in DDWoR group [(6.1±1.4) mm] (P<0.05). The inter-condyle angle presented significantly larger in biND group (136°±13°) and uniDD group (132°±14°) than that inbiDD group (124°±17°) (P<0.05). Conclusions: The mandibular condylar morphology changes significantly presented in the patients with temporomandibular disc displacement for the temporomandibular disorders.
2022-12-31T05:53:41.884Z
6,546,300
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/ICUMT.2010.5676623", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
Wireless Sensor Networks (WSN) support data collection and distributed data processing by means of very small sensing devices that are easy to tamper and cloning: therefore classical security solutions based on access control and strong authentication are difficult to deploy. In this paper we look at the problem of assessing security of node localization. In particular, we analyze the scenario in which Verifiable Multilateration is used to localize nodes and a malicious node try to masquerade as non-malicious. We resort to non-cooperative game theory and we model this scenario as a two-player game. We analyze the optimal players' strategy and we show that the Verifiable Multilateration is indeed a proper mechanism able to reduce the profitability of fake positions. Our analysis demonstrates that, when the verifiers play a pure strategy, the malicious node can always masquerade as unknown with a probability of one and the induced deception could be not negligible. Instead, when the verifiers play mixed strategies, the malicious node can masquerade as unknown with a very low probability and the expected deception is virtually negligible.
2023-01-02T04:19:44.896Z
154,510,640
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1177/001088047901900405", "MAG": "2116601935", "PubMedCentral": null }, "license": null, "status": null, "url": null }
A new exercise teaches hotel managers and department heads the principles of integrated hotel management - illustrat ing ways to resolve conflicts between the concerns of different departments and ...
2022-02-09T01:48:20.170Z
244,062,821
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/tcsii.2021.3125801", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
A novel widely-linear quaternion multiband-structured subband adaptive filter (WL-QMSAF) algorithm is proposed for further enhancing the convergence rate of estimation error when input signals are greatly correlated in the quaternion domain. Using the derivative rule in GHR-calculus, the WL-QMSAF algorithm is developed on the basis of the principle of minimum fluctuations. The proposed WL-QMSAF algorithm decomposes the input signal into multiple parallel channels to promote more effective signal processing. Since quaternion widely linear model is able to describe complete second-order statistics of input signal, the proposed algorithm can effectively process both Q-proper and Q-improper signals. In addition, the analysis of mean-square steady state for the WL-QMSAF algorithm is performed according to the principle of energy conservation. Finally, numerical simulations are conducted on circular data as well as noncircular data to support the steady-state analysis of mean-square error as well as validate the effectiveness of the proposed WL-QMSAF algorithm.
2022-03-23T13:28:31.193Z
96,271,141
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1063/1.462192", "MAG": "2034459294", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Calculations of rate coefficients for the fast reaction of a structureless ion with a dipolar linear molecule in a 2Π electronic state are presented. The rotationally adiabatic capture theory is used together with a simple classical electrostatic potential. An analytical formula is derived for the rate coefficient in the low temperature limit. The reaction of H+3 with OH(X 2Π) is taken as an example. For temperatures less than 90 K, the rate coefficients differ from those calculated for molecules in 1Σ states. The most interesting new prediction is that the rate coefficient for the reaction of a 2Π polar molecule with an ion is proportional to T−1/2 for temperatures close to absolute zero.
2022-12-20T12:57:23.054Z
19,439,202
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1079/BER2003284", "MAG": "2005621492", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Abstract The chalcid, Oomyzus sokolowskii Kurdjumov has been recorded in many parts of the world as a major larval–pupal, gregarious endoparasitoid of the diamondback moth, Plutella xylostella (Linnaeus), a serious pest of brassica vegetable crops worldwide. This study investigated intraspecific variation between two populations of O. sokiolowskii, one from Cape Verde Islands, West Africa and the other from Hangzhou, China. In all crosses and backcrosses between the two geographical populations, the numbers of progeny and sex ratio of progeny were similar to those obtained within each of the populations, demonstrating complete reproductive compatibility between the two populations. The two populations showed similar responses to temperature with respect to development time and survival of immature stages. Observations on the interactions between the two O. sokolowskii populations and Cotesia plutellae (Kurdjumov), another major parasitoid of P. xylostella, showed that neither population could achieve successful parasitism of P. xylostella larvae already parasitized by C. plutellae. However, both O. sokolowskii populations could achieve hyperparasitism by ovipositing into a mid-late stage larva of C. plutellae developing inside the primary host. Contrary to earlier reports, no evidence of intraspecific variations in ability to hyperparasitize between these two populations of O. sokolowskii was found.
2022-12-23T21:53:45.831Z
255,262,728
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2147/prbm.s381968", "MAG": null, "PubMedCentral": null }, "license": "CCBYNC", "status": "GOLD", "url": "https://www.dovepress.com/getfile.php?fileID=86466" }
Purpose: Previous studies are based on social exchange theory to explore the influence of leadership style on employees’ deviant innovation behavior. However, deviant innovation is risky, not supported by the organization, and is expected to benefit the long-term development of the organization. The key to the problem lies in how to guide employees to think and solve problems from the perspective of the organization, instead of just relying on material or spiritual exchange and return. Therefore, the purpose of this study was to analyze the relationship between coaching leadership, interactional justice, organizational identification and employees’ deviant innovation from the perspective of changing cognition. Methods: This work surveyed employees in 26 Chinese enterprises in more than 10 regions. Questionnaires were distributed to 450 employees, the first round of survey mainly investigated demographic information of employees and coaching leadership style of supervisors, and the second round of survey mainly investigated employees’ organizational identification, interactional justice, and deviant innovation behavior. By tracking and matching, 340 valid questionnaires were finally obtained. Spss 22.0 was used to describe all the study variables; Mplus 7.0 is used to carry out a confirmatory factor analysis and a multi-path regression model. Results: According to self-categorization theory, the results demonstrated that coaching leadership can directly or indirectly promote employees’ deviant innovation behavior through the dual-path intermediary and chain intermediary of interactional fairness and organizational identification. Conclusion: Under the open situation created by coaching leadership, coaching leaders will interact and communicate sincerely with employees, and employees’ cognition will change. The original “I” of employees will be transformed into “big self” with organizational membership, which will guide employees to show behaviors beneficial to the organization. Therefore, interactional justice and organizational identification can play a key role of the influence of coaching leadership on employees’ deviant innovation behavior.
2022-12-31T18:42:31.679Z
187,441,441
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.32938/ag.v2i04.311", "MAG": "2899927126", "PubMedCentral": null }, "license": "CCBYNC", "status": "GOLD", "url": "https://savana-cendana.id/index.php/AG/article/download/311/169" }
Jagung di pulau Timor masih menjadi bahan makanan pokok bagi sebagian besar masyarakat di pedesaan sehingga selalu dibudidayakan pada saat musim hujan. Tujuan penelitian ini adalah untuk mengetahui 1) gambaran USAhatani jagung; dan 2) pendapatan USAhatani njagung Kelompok Tani Oelbubuk di Desa Oeolo Kecamatan Musi Kabupaten TTU. Penelitian dilaksanakan di kelompok tani Oelbubuk, desa Oeolo, Kecamatan Musi, Kabupaten TTU, pada Bulan Januari sampai Agustus 2016. Teknik pengambilan sampel dalam penelitian ini menggunakan teknik sensus sehingga semua anggota kelompok tani menjadi responden yakni 20 responden. Untuk menjawab tujuan pertama digunakan metode analisis deskriptif kualitatif, sedangkan untuk menjawab kedua dilakukan analisis pendapatan. Hasil penelitian menunjukkan bahwa jagung yang dibudidayakan adalah jagung lokal yang dipersiapkan dari musim panen tahun lalu. Persiapan lahan dilakukan dengan memilih lahan yang akan mencukupi bagi seluruh anggota kelompok tani selanjutnya melakukan pembersihan dengan sistem tebas bakar pada lahan yang akan diolah. Penanaman jagung dilakukan pada bulan September-November dengan membuat lubang tanam dengan kedalaman 2,5 cm dan pada tiap lubang ditanami 3-4 biji jagung dengan jarak tanam 40-50 cm. Penyiangan dilakukan sekali dalam seminggu dengan menggunakan Roundup untuk membasmi gulma yang tumbuh di antara tanaman. Pupuk yang digunakan yaitu pupuk kandang. Jagung dipanen setelah berumur 95-100 hari. Panen dilakukan dengan cara memetik jagung dalam bentuk berkelobot setelah itu jagung dijemur di bawah sinar matahari hingga kering kemudian disimpan dan hasil produksinya siap untuk dipasarkan. Produksi pada musim panen tahun 2016 berkisar antara 195-250 kg dengan total keseluruhan produksi USAhatani jagung sebesar 4.648 kg. Total produksi yang dijual sebesar 3,448 kg dengan harga jual Rp. 3.500/kg. Total penerimaan kelompok tani Oelbubuk sebesar Rp. 12,068,000. dengan rata-rata Rp. 603.400 per anggota. Pendapatan total sebesar Rp. 5,732,500 dengan rata-rata pendapatan masing-masing anggota sebesarn Rp. 286,625. per musim tanam. ©2017 dipublikasikan oleh Agrimor.
2022-01-24T20:52:27.583Z
245,816,605
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.13056/acamh.4621", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
In this podcast, Dr Alan Cooklin and Jessica Streeting discuss the impact of parental mental illness, how family psychiatry has developed, how everyone has a key role to play, and the power of explanation and understanding as a protective intervention.
2022-01-24T22:11:59.124Z
243,026,472
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.21203/rs.3.rs-78089/v1", "MAG": null, "PubMedCentral": null }, "license": "CCBY", "status": "GREEN", "url": "https://www.researchsquare.com/article/rs-78089/v1.pdf?c=1631870829000" }
BACKGROUND Cisplatin is commonly used in lung cancer therapy, but cisplatin resistance in lung cancer cells remains an unsolved problem. Here, we report that cytoplasmic APE1 contributes to cisplatin resistance, cell proliferation and migration in lung cancer cells. METHODS Immunofluorescence, western blot analysis, lentivirus transfection and scratch assays, and transwell migration and invasion assays were carried out on the cell lines A549 and Calu-1. A total of 124 samples of lung cancer tissues were evaluated to determine the clinical effects of cytoplasmic APE1 and COX-2. RESULTS We found that cytoplasmic APE1 expression was lower in cisplatin sensitive cells than in cisplatin-resistant cells, and the upregulation of cytoplasmic APE1 significantly reduced cisplatin sensitivity in lung cancer cells. Gain-of-function studies demonstrated that cytoplasmic APE1 promoted lung cancer cell proliferation, migration and invasion in vitro and tumor growth in vivo, which were inhibited after cisplatin treatment. In patient samples, cytoplasmic APE1 in lung cancer tissues was an independent indicator of overall survive (OS) for lung cancer patients (P < 0.001). Mechanistic studies revealed that cytoplasmic APE1 promotes lung cancer malignancy by activating the COX-2/Akt/β-catenin pathway. Furthermore, the mutation of the APE1-C65 site caused upregulation of cytoplasmic APE1 and inhibited cell growth, migration and invasion of lung cancer cells. CONCLUSION We suggest that modulating cytoplasmic APE1 in lung cancer is a promising novel strategy for overcoming cisplatin resistance.
2022-07-31T10:28:31.088Z
177,325,042
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/02102412.2008.10779648", "MAG": "2041499329", "PubMedCentral": null }, "license": null, "status": null, "url": null }
RESUMEN En este trabajo se analiza, para el período 1996–2005, la producción científica contable publicada en las revistas españolas. El objetivo es determinar quién y dónde se publica, cuál es la calidad de la investigación, si existe algún factor determinante de la actividad investigadora y cuál es su evolución. Se concluye que los profesores de contabilidad activos en investigación mantienen un nivel razonable de producción científica, aunque dicha productividad queda relativizada al incorporar los factores de impacto como indicadores de calidad. Detectamos un importante grado de concentración en revistas propias del área así como un cierto factor institucional, asociado tanto a departamentos como a programas de doctorado. El índice de colaboración muestra un cambio de tendencia, orientado hacia el aumento del trabajo en equipo.
2022-09-15T07:51:19.681Z
253,251,992
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/CSW55288.2022.9930347", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
Combining hyperspectral and polarimetric imaging provides a powerful sensing modality with broad applications from astronomy to biology. Existing methods rely on temporal data acquisition or snapshot imaging of spatially separated detectors. These approaches incur fundamental artifacts that degrade imaging performance. To overcome these limitations, we present a stomatopod-inspired sensor capable of snapshot hyperspectral and polarization sensing along a single optical axis. The design relies on the unique optoelectronic properties of semiconductor polymers. By orienting the polymers in the plane of the film, the photodetectors become intrinsically polarization sensitive. The detectors can also be made semitransparent enabling multiple detectors to be stacked along the path of light. We exploit these attributes to achieve multiple spectral and polarization channels simultaneously by stacking the polarization sensitive detectors along with polymer retarders with specific chromatic dispersion. We show that this design can sense up to 15 spectral channels over a 350-nm bandwidth. A detector is also demonstrated with the ability to simultaneously register four spectral channels and three polarization channels. The talk will conclude with a discussion on how this bio-inspired design opens up a range of opportunities for high performance and tailored spectral and polarimetric imaging.
2022-11-06T17:46:02.230Z
548,660
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1107/S1600536812004400", "MAG": "2238995375", "PubMedCentral": "3297233" }, "license": null, "status": null, "url": null }
The title complex, [Cd(C6H17N3)2](ClO4)(NO3), was synthesized by the reaction of Cd(NO3)2·4H2O, bis(3-aminopropyl)amine and sodium perchlorate in methanol. The asymmetric unit of the title complex consists of one Cd2+ cation, two tridentate bis(3-aminopropyl)amine ligands, one nitrate anion and one perchlorate anion. The Cd2+ cation is coordinated by six N atoms of the bis(3-aminopropyl)amine ligands in a slightly distorted octahedral coordination geometry. In the crystal, molecules are held together by an intricate network of N—H⋯O interactions. One of the two amine ligands was found to be disordered over two sets of sites, with a ratio of 0.802 (3):0.198 (3), similarly to the nitrate anion, with a ratio of 0.762 (10):0.238 (10).
2022-11-11T08:25:35.176Z
242,006,891
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.31227/osf.io/w5bps", "MAG": null, "PubMedCentral": null }, "license": null, "status": "GREEN", "url": "https://osf.io/w5bps/download" }
Potensi laut di Indonesia yang sangat berlimpah merupakan salah satu faktor yang mendukungketahanan pangan Indonesia, salah satu hasil laut indoneisa adalah rumput laut. Sargassumpolycystum merupakan salah satu rumput laut yang mempunyai serat tinggi dan banyak tumbuh diperairan Indonesia. Alga coklat Sargassum polycystum menghasilkan polisakarida yang berbeda yaitualginate, laminarins, dan fucoidan. Fucoidan adalah polisakarida yang terdiri dari L-fruktosa, asamurinoic, galaktosa, xilosa, dan sulfur ester. Beberapa penelitian menyebutkan Fucoidans berfungsisebagai antikoagulan anti-thrombogenic, anti-tumor, antivirus, anti-inflamasi dan zat anti oksidan.Tujuan dari penelitian ini untuk mengidentifikasi fucoidan dari alga coklat Sargassum polycystum yangdiharapkan dapat mendukung ketahanan pangan Indonesia. Metode yang digunakan adalah metodedeskriptif dan eksploratif. Parameter uji yang dilakukan untuk mengidentifikasi senyawa aktif fucoidanmenggunakan metode spektrofotometer UV-VIS dan FTIR serta analisis proksimat dari ekstrak kasarfucoidan. Hasil ekstrak kasar fucoidan Sargassum polycystum didapatkan hasil uji proksimat yaituprotein sebesar 0.22%, lemak 0.08%, air 83.77%, abu 10.19%, dan karbohidrat sebesar 5.74%. Hasiluji spektrofotometer UV-VIS didapatkan panjang gelombang pada peak 262.5 nm, dan untuk hasilFTIR menunjukkan adanya gugus karboksilat, untuk gugus hidroksil, dan gugus sulfat.
2022-04-22T11:45:37.791Z
5,781,524
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1175/1520-0485(2003)033<1877:AMTMVB>2.0.CO;2", "MAG": "2132553346", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The possibility of generating decadal ENSO variability via an ocean teleconnection to the midlatitude Pacific is studied. This is done by analyzing the sensitivity of the equatorial stratification to midlatitude processes using an ocean general circulation model, the adjoint method, and a quasigeostrophic normal-mode stability analysis. It is found that, on timescales of 2‐15 yr, the equatorial Pacific is most sensitive to midlatitude planetary Rossby waves traveling from the midlatitudes toward the western boundary and then to the equator. Those waves that propagate through baroclinically unstable parts of the subtropical gyre are amplified by the baroclinic instability and therefore dominate the midlatitude signal arriving at the equator. This result implies that decadal variability in the midlatitude Pacific would be efficiently transmitted to the equatorial Pacific from specific areas of the midlatitude Pacific that are baroclinically unstable, such as the near-equatorial edges of the subtropical gyres (158N and 128S). The Rossby waves that propagate via the baroclinically unstable areas are of the advective mode type, which follow the gyre circulation to some degree and arrive from as far as 258N and 308S in the east Pacific. It is shown that the baroclinic instability amplifying these waves involves critical layers due to the vertical shear of the subtropical gyre circulation, at depths of 150‐200 m.
2022-12-17T01:27:49.958Z
134,241,882
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.11575/PRISM/10211", "MAG": "2793326106", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Our National Parks afford a great opportunity to study natural ecological processes that are more intensely managed in other jurisdictions. In 1999 a plant community diversity study was undertaken in Vermilion Pass, Kootenay National Park, an area along the Continental Divide that burned in July 1968. This research is a component in a broader mandate the vegetative composition of the Vermilion Burn in 1999 was compared to the immediate postfire composition, mapped by Dr. Stuart Harris in 1971. Hierarchical cluster analysis of a stratified random sample of 217 vegetation plots was used to determine the vegetative composition of 10 distinct plant communities. Indicator species were then used to model the distribution of plant communities throughout the burn against topographic and terrain-related variables. This research points to the need in Parks management policy to implement a longitudinal fire ecology study, to be performed regularly throughout the duration of a bicentennial fire return interval within the mountain parks. The goals of such a study might include an increased understanding of plant community succession within naturally regenerating burns, the unique possibility parks afford to compare natural regeneration to that found in altered burn areas or replanted clearcuts, or the assessment of changes that fire catalyses in associated plant communities such as avalanche paths.
2022-02-09T12:15:14.354Z
10,818,543
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.5120/4832-7090", "MAG": "2112170296", "PubMedCentral": null }, "license": null, "status": "BRONZE", "url": "https://doi.org/10.5120/4832-7090" }
Digital VLSI implementation of an auditory filter for speech processor of cochlear implant (CI) is proposed. Optimized design for hardware implementation of the filter with respect to area, power and speed is the significant criterion for the implementation of auditory filter for a CI. A digital filter is designed using the System Generator10.1 through the mathematical model of the FIR filter developed in Simulink using FDA tool. It is further downloaded onto the Spartan 3E FPGA Kit. Translation of the Simulink model into a hardware realization is done using system generator. Thus simulation is done both in the hardware and software environment. VHDL code for the filter is developed using the coefficients generated from FDA tool of System generator. The area, power and delay analysis for the design is done using SYNOPSYS Design Vision tool with 180micron technology. General Terms Auditory filter, VLSI Signal Processing,
2022-06-06T08:05:11.739Z
108,541,563
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.12739/NWSAES.V6I1.5000067015.G5000062382", "MAG": "1896287754", "PubMedCentral": null }, "license": null, "status": null, "url": null }
In the development and design of new products in ceramic industry unlimited number of trials has to be carried out to obtain the appropriate format due to the deformation. These trials lead to increased costs and loss of labor in the production stage. In this study, it is aimed to develop computer software to reduce these losses in the ceramic industry. In this work, in different compositions, firing temperatures and sintering times cylindrical form samples are created. These samples, after the drying process have been scanned with the 3D scanner at the same time measured using classical methods. Later on these samples are fired at different sintering times and temperatures in ceramic firing and measured using the same methods. Thus the deformations in the base, side and mouth regions of the cylindrical samples are identified. In the light of this experimental data fuzzy systems have been designed. In the fuzzy system, the firing temperature, sintering time and composition of ceramic samples have been used as the input data while the amount of deformation is used as the output data. In the fuzzy system we have developed, an accuracy of 80% for the base deformation, 77.5% for the edge deformation and 55% for the mouth deformation of the cylindrical form have been achieved. However, in determining the deformation of the square form the targeted results have not been obtained.
2022-02-10T06:59:35.613Z
225,581,888
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.31005/iajmh.v3i0.134", "MAG": "3046924423", "PubMedCentral": null }, "license": null, "status": "BRONZE", "url": "https://iajmh.emnuvens.com.br/iajmh/article/download/134/160" }
O objetivo deste estudo foi mapear a produção científica sobre COVID-19, através de uma análise bibliométrica. Os procedimentos metodológicos foram delineados por uma abordagem quantitativa, a pesquisa envolveu dados retirados do banco de dados científicos Scopus. A palavra-chave "COVID-19" foi utilizada para as buscas no referido banco de dados, dentro de um período de janeiro de 2019 a 01 de junho de 2020. Nas buscas foram identificadas 5.570 publicações relacionadas ao tema. O ano com o maior número de publicações foi o ano de 2020, com 5.560 publicações. Quanto às áreas de publicação do artigo, as que mais se destacaram foram: Medicina e Bioquímica, Genética e Biologia Molecular, com 4.161 e 594 artigos publicados, respectivamente. Entre os periódicos, o BMJ Clinical Research Ed obteve o maior número de publicações sobre o tema pesquisado. China e EUA foram os países que mais publicaram artigos e o idioma mais utilizado foi o inglês.
2022-09-09T05:13:49.902Z
34,094,620
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/IRMMW-THZ.2012.6380260", "MAG": "2074457706", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This paper presented a novel millimeter-wave output power accurate controlled method, achieved 32dB±0.3dB dynamic output power controlled range. Moreover, this paper developed a W-Band high power solid-state signal source for further 0.3THz-0.4THz imaging application, achieved at least +12dBm output power range from 75GHz to 110GHz.
2022-02-12T09:37:41.402Z
28,826,788
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3928/0147-7447-20000501-11", "MAG": "2287519032", "PubMedCentral": null }, "license": null, "status": null, "url": null }
As an alternative to a limited vendor/volume discount approach, our hospital employed a physician-driven free market strategy aimed at reducing joint implant costs. Surgeons were provided with vendor pricing and peer profile comparisons of implant cost data and asked to select implants providing the best value based on patient need. Vendors were challenged to reduce prices where appropriate. Total savings based on the 1995-1997 volume-adjusted cost difference were $1,059,159, a 17.5% decrease. These results demonstrate the possibility of reducing joint implant costs using a strategy that does not limit vendors or cap prices.
2022-12-15T13:00:30.115Z
248,458,648
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3390/cancers14092237", "MAG": null, "PubMedCentral": "9103173" }, "license": "CCBY", "status": "GOLD", "url": "https://www.mdpi.com/2072-6694/14/9/2237/pdf?version=1651241734" }
Simple Summary Nerve fibers in the microenvironment have shown notable prognostic potential in various malignancies; however, its role in hepatocellular carcinoma remains to be elucidated. Therefore, the impact of nerve fibers on oncological survival was investigated in a large European cohort of patients with hepatocellular carcinoma who underwent curative-intent liver resection. By means of univariate and multivariate statistics as well as group comparisons of patients with and without nerve fibers, the presence of nerve fibers itself, as well as the corresponding density, was not shown to be associated with survival or the risk of tumor recurrence. Despite being of major prognostic value in various cancer types, nerve fibers in the microenvironment of hepatocellular carcinoma could not be used as a prognostic biomarker in these patients. Abstract It has been shown that the presence and density of nerve fibers (NFs; NFD) in the tumor microenvironment (TME) may play an important prognostic role in predicting long-term oncological outcomes in various malignancies. However, the role of NFD in the prognosis of hepatocellular carcinoma (HCC) is yet to be explored. To this end, we aimed to investigate the impact of NFs on oncological outcomes in a large European single-center cohort of HCC patients. In total, 153 HCC patients who underwent partial hepatectomy in a curative-intent setting between 2010 and 2021 at our university hospital were included in this study. Group comparisons between patients with and without NFs were conducted and the association of recurrence-free survival (RFS) and overall survival (OS) with the presence of NFs and other clinico-pathological variables were determined by univariate and multivariable Cox regression models. Patients with NFs in the TME presented with a median OS of 66 months (95% CI: 30–102) compared to 42 months (95% CI: 20–63) for patients without NFs (p = 0.804 log-rank). Further, RFS was 26 months (95% CI: 12–40) for patients with NFs compared to 18 months (95% CI: 9–27) for patients without NFs (p = 0.666 log-rank). In a subgroup analysis, patients with NFD ≤ 5 showed a median OS of 54 months (95% CI: 11–97) compared to 48 months (95% CI: 0–106) for the group of patients with NFD > 5 (p = 0.787 log-rank). Correspondingly, the RFS was 26 months (95% CI: 10–42) in patients with NFD ≤ 5 and 29 months (95% CI: 14–44) for the subcohort with NFD > 5 (p = 0.421 log-rank). Further, group comparisons showed no clinico-pathological differences between patients with NFs (n = 76) and without NFs (n = 77) and NFs were not associated with OS (p = 0.806) and RFS (p = 0.322) in our Cox regression models. In contrast to observations in various malignancies, NFs in the TME and NFD are not associated with long-term oncological outcomes in HCC patients undergoing surgery.
2022-12-20T11:06:37.005Z
237,920,254
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.32833/MAJEM.V10I1.138", "MAG": "3183997320", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Penelitian ini bertujuan untuk mengetahui dampak adanya sertifikasi halal pada produk makan olahan terhadap minat beli masyakat muslim di Kota Kendari.. Metode penelitian merupakan metode survei dan alat analisis yag digunakan adalah regresi linier berganda, jumlah sampel yang digunakan dalam penelitian ini sebanyak 100 responden. Metode pengumpulan data yang digunakan adalah kuesioner dan dokumentasi.  Hasil penelitian ini menunjukkan bahwa konsumen secara keseluruhan menyatakan bahwa bahan makanan olahan yang memiliki sertifikasi halal dan makanan yang bersertifikasi halal merupakan hal yang sangat penting diketahui sebelum makanan tersebut dikonsumsi, Berdasarkan  hasil olahan data meunjukkan bahwa variable sertifikasi halal dan variable bahan makanan olahan mempunyai pengaruh signifikan terhadap minat beli konsumen baik secara parsial maupun secara simultan
2022-01-27T07:16:54.070Z
81,473,641
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1017/cjn.2018.298", "MAG": "2884243362", "PubMedCentral": null }, "license": null, "status": "BRONZE", "url": "https://www.cambridge.org/core/services/aop-cambridge-core/content/view/64EA6903FEA0B43159AF92FD687A159B/S0317167118002986a.pdf/div-class-title-exploring-cellular-subpopulations-in-glioblastoma-and-matched-organoids-using-single-cell-rna-seq-div.pdf" }
Background: Gliomas are the most common and fatal adult brain tumor with distinct genomic subgroups defined by isocitrate dehydrogenase (IDH) mutation status. Mutations in IDH result in overproduction of the oncometabolite 2-hydroxyglutarate (2HG). The landscape of metabolic changes that define gliomas has not previously been explored. Methods: We performed liquid chromotography-mass spectrometry (LC-MS) to examine over 700 metabolites on 90 fresh-frozen glioma samples (30 IDH-wildtype, 30 IDH-mutant 1p/19q codeleted, 30 IDH-mutant 1p/19q non-codeleted) from our institutional biobank. R and S enantiomers of 2HG were quantified using high pressure liquid chromatography tandem mass spectrometry coupled with a CHIROBIOTIC R column. Genome wide DNA methylation was performed on all tumors using Illumina 850k EPIC array. Unsupervised consensus clustering of differentially expressed metabolites and methylated post-processed probes was performed. Copy number variations were determined based on intensity values of the methylation array. Survival of unsupervised cluster groups was determined using the Kaplan-Meier Estimate. Results: Unsupervised clustering of 689 metabolites revealed 2 distinct subgroups of gliomas associated with recurrence-free survival (RFS, P = 0.021). IDH mutant tumours were found in both cluster groups where as IDH-wildtype tumors were found only in Group 2. Group 2 IDH-mutant tumors had unfavourable PFS, higher R/S-2HG levels, and higher proportion of copy number alterations (4q, 9p, 13q, 17q) compared to group 1 IDH-mutant tumors (P=0.048, P=0.0194, P<0.0001 respectively) compared to group 1 IDH-mutant tumors. (P= p=0.048). . Conclusions: Metabolic profiling of gliomas reveals 2 distinct subtypes of IDH-mutant independent of 1p/19q codeletion status with differing survival patterns and large scale chromosomal alterations that may be driven by varying levels of R/S-2HG.
2022-01-27T19:57:17.672Z
251,338,421
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.36106/ijsr/6701771", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
Advanced age is associated with an increased response to autoantigens, although the implications of MG's age and sex-specic frequency distribution in pathogenesis remain unclear. In the last two decades, the trend has shown a progression in several MG patients, which urges the need to dene better prevention and treatment guidelines. Early diagnosis and risk factor screening play a key role in knowing more about MG's pathogenesis and therapeutic modalities. In this article we have reviewed the latest in the genomics of myasthenia gravis.
2022-08-12T08:45:11.985Z
233,701,342
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.32848/AGRAR.INNOV.2020.3.7", "MAG": "3139282153", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Компостування – один із найбільш поширених мето- дів сумісної утилізації відходів рослинницької та тва- ринницької галузей. Застосування прогресивної тех- нології сумісного компостування гною великої рогатої худоби та відходів вирощування продукції рослинни- цтва із застосуванням мікробних препаратів дозво- лить отримати біокомпост. Його основною перевагою перед іншими компостами є дешевизна. Окрім цього, використанням даної технології можна вирішити низку екологічних проблем. Мета наших досліджень – розро- бити технологію спільної утилізації відходів рослинни- цтва та тваринництва з використання мікробіологічних препаратів. Методи. Для проведення досліджень із вермикультивування і вермикомпостування була при- готовлена серія органічних субстратів, що містять різні види органічних відходів тваринництва та рослинни- цтва: солома ячмінна, солома пшенична, кукурудзяна дробина, а також рідкі екскременти ВРХ, видалені за допомогою гідрозмиву. Кожна з перелічених вище органічних решток була змішана із гноївкою (рН – 5,8) у співвідношенні 1 : 1. Усі органічні компоненти (крім торфу) попередньо були подрібнені до пастоподібного стану. Результати. Аеробне компостування з коротким терміном перебігу біохімічних процесів, де відходи тва- ринництва і рослинництва вивозяться на спеціальний гідроізольований майданчик, обладнаний системою перфорованих труб для подачі повітря та відведення інфільтрату. Відходи складуються в кагати пошарово, з обов’язковою обробкою кожного шару мікробіологіч- ним препаратом – ЕМ Біоактив або ЕМ Компост. Перебіг мікробіологічних процесів розкладу та знеза- раження компостної суміші інтенсифікується заміщен- ням облігатних мікроорганізмів органічного наповнювача факультативними препарату. Періодично контролю- ються температура, вологість і вміст СО2 в кагаті. У разі дотримання всіх технологічних вимог після завершення компостування об’єм кагату зменшиться на 40–60%. Процентне коливання залежить від виду наповнювачів, які використовувалися. Рекомендована норма внесення готового продукту становить 3–10 тонн на гектар, залежно від гранулометричного складу ґрунту та ступеня його гумусованості. Завдяки використанню ЕМ-препаратів компост абсо- лютно безпечний у санітарно-епідеміологічному плані, адже не містить патогенної мікрофлори та позбавлений неприємного запаху, може використовуватись у різних галузях сільського господарства. Висновки. Технологія компостування з отриманням ЕМ-компосту аеробним способом є ресурсозбережувальною технологією, адже не потребує великої кількості машин і обладнання. ЕМ-компост – це запорука екологічної стабільності регі- ону та держави загалом завдяки отриманню якісних та сталих врожаїв, підвищенню рентабельності тварин- ницької галузі.
2022-10-28T00:50:02.470Z
233,523,006
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3390/W13070989", "MAG": "3143633889", "PubMedCentral": null }, "license": null, "status": null, "url": null }
In this study, an extreme event observed at the intermittent Mediterranean Bogdanas River within the territory of the protected area of the National Park of Lakes Koronia-Volvi and Macedonian Temp that led to a mass fish kill was investigated. We aimed to define the main pressures affecting water quality and biota, specifically fish. No organic poisons, pesticides or heavy metal concentrations were detected in fish tissue, while high values of BOD5, COD, TN and conductivity were measured in water samples. These results, combined with the prevailing hydroclimatic factors (high temperatures and low water flow), lead to the assumption that mass fish mortality was triggered by high organic loads discharged from an upstream point source of pollution, and in particular an active landfill.
2022-12-02T16:56:13.964Z
33,966,762
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1111/J.1536-7150.2011.00811.X", "MAG": "1878137126", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The neoliberal consensus is that state funded pensions are not sustainable in the long term, due to declining fertility and longevity. In response, policymakers have pointed to the advantages of privately funded pension systems. This article compares the social provisioning of these two systems using the circular flow of income as an organizing framework. A series of pitfalls in the private model are examined, including inequality of provision, mis-selling of investment products, and punitive charges.
2022-12-12T13:21:25.211Z
153,382,116
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/03088839800000046", "MAG": "1995604662", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This paper examines the role of management training on entrepreneurial development paths of a sample of small and medium-sized Italian shipping enterprises. Starting with an analysis of evolutionary dynamics at the international level and highlighting the peculiarities of shipping in Italy, this paper reveals teh importance of firm-specific factors, compared with country-specific factors, in determining the competitiveness of shipping companies. In such enterprises the entrepreneur's role and his/her level of entrepreneurial culture play an important part in conditioning developing paths. On the basis of the results from an empirical survey, thee study in question suggests several implications for implementing policies aimed at increasing the level of entrepreneurial culture by means of selective, diversified interventions in management training so as to develop the factors required by the firm to recover competitiveness.
2022-12-13T07:00:57.608Z
57,109,248
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1056/NEJMSA060373", "MAG": "2041950088", "PubMedCentral": null }, "license": null, "status": null, "url": null }
In the 115th annual Shattuck Lecture, Dr. Ronald Arky, the 2005 speaker, considers the history and science of medical education, discusses its current disjointed state, and calls for a restructuring of continuing medical education.
2022-12-13T15:00:15.032Z
40,401,819
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.4097/kjae.2017.70.5.493", "MAG": "2766497529", "PubMedCentral": "5645581" }, "license": "CCBYNC", "status": "GOLD", "url": "http://ekja.org/upload/pdf/kjae-70-493.pdf" }
Smartphones and electronic tablets (e-tablets) have become ubiquitous devices. Their ease of use, smartness, accessibility, mobility and connectivity create unique opportunities to improve quality of surgical care from prehabilitation to rehabilitation. Before surgery, digital applications (Apps), serious games and text messaging may help for a better control of risk factors (hypertension, overweight), for smoking cessation, and for optimizing adherence to preoperative recommendations (e.g., regarding anticoagulation or antihypertensive treatments). During surgery, Apps may help to rationalize fluid management and estimate blood loss. After surgery, smartphones and/or connected sensors (pulse oximeter, adhesive path, electronic tattoo, bioimpedance necklace) can be used to monitor body temperature, heart rate, heart rate variability (detection of cardiac arrhythmia), respiratory rate, arterial oxygen saturation and thoracic fluid content. Therefore, these tools have potential for the early detection of infectious, cardiac and respiratory complications in the wards and from home. When connected to echo probes, smartphones and e-tablets can also be used as ultrasound devices during central venous catheter insertion, for peripheral nerve blocks, and to perform echocardiography in patients developing cardiac complications. Finally, electronic checklists now exist as Apps to enhance communication between patients and healthcare professionals, and to track and record step by step each element of the surgical journey. Studies are now urgently needed to investigate whether this digital revolution can translate into a better outcome, an earlier detection of postoperative complications, a decrease in hospital readmissions and in health care costs.
2022-12-15T09:01:15.854Z
169,683,556
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3846/BTP.2018.20", "MAG": "2900456803", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The primary purpose of this study was to explore the relationship between scenario planning and strategic performance. The data was collected from 121 Multinational corporations operating in Jordan by using a questionnaire. Pearson correlation and the partial least squares (PLS) methodology for factor analysis and path modelling was used to test the study hypotheses. The study found a positive and statistically significant relationships between scenario planning and the four components of strategic performance: financial performance, customer performance, learning and growth, and internal business processes. Based on these findings, the study recommends that managers should apply scenario planning practices to enhance the levels of strategic performance in their companies. Additionally, managers should raise the awareness of their employees regarding the importance of both scenario planning and strategic performance. Moreover, managers should provide their employees with adequate training courses in relation to acquire the knowledge and build their skills in the field of scenario planning. Finally, managers should use the diagnostic instruments that developed by previous research to assess a company’s strategic performance and scenario planning practices, identify managerial practices that need to be implemented or improved, and determine the resources that might realistically be required to build a better scenario planning process and promote strategic performance. Much more research and studies need to be performed in this budding subject. Links among scenario planning and another organizational topics and outcomes need to be searched.
2022-12-26T19:03:14.611Z
219,804,544
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1257/PANDP.20201102", "MAG": "2999661510", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This essay discusses a new approach to macroeconomics called modern monetary theory (MMT). It identifies the key differences between MMT and the approach found in mainstream textbooks. It concludes that while MMT contains some kernels of truth, its most novel policy prescriptions do not follow cogently from its premises.
2022-12-29T18:26:38.243Z
211,171,522
{ "externalids": { "ACL": null, "ArXiv": "2002.08040", "DOI": "10.1109/TCOMM.2020.2986289", "MAG": "3008643354", "PubMedCentral": null }, "license": null, "status": null, "url": null }
In the current unmanned aircraft systems (UASs) for sensing services, unmanned aerial vehicles (UAVs) transmit their sensory data to terrestrial mobile devices over the unlicensed spectrum. However, the interference from surrounding terminals is uncontrollable due to the opportunistic channel access. In this paper, we consider a cellular Internet of UAVs to guarantee the Quality-of-Service (QoS), where the sensory data can be transmitted to the mobile devices either by UAV-to-Device (U2D) communications over cellular networks, or directly through the base station (BS). Since UAVs’ sensing and transmission may influence their trajectories, we study the trajectory design problem for UAVs in consideration of their sensing and transmission. This is a Markov decision problem (MDP) with a large state-action space, and thus, we utilize multi-agent deep reinforcement learning (DRL) to approximate the state-action space, and then propose a multi-UAV trajectory design algorithm to solve this problem. Simulation results show that our proposed algorithm can achieve a higher total utility than policy gradient algorithm and single-agent algorithm.
2022-12-31T18:13:35.995Z
21,847,169
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/38.75595", "MAG": "1992138433", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Two European projects-the Euroworkstation and Spirit-aimed at producing the next generation of multiprocessor, high-performance, extensible workstations are discussed. The goal is to compete with US products currently dominating the market. The two projects also aim to satisfy various levels of graphics performance: flight simulators that render scenes at interactive rates, various forms of animation, and high-quality, static scene rendering. The architecture, hardware and software of each approach are examined. >
2022-01-27T13:52:02.734Z
171,823,939
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.26754/OJS_ARIF/A.RIF.201621571", "MAG": "2593670925", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Resena del libro  Jurgen Habermas, En la espiral de la tecnocracia. Traduccion de David Hereza Modrego y Fernando Garcia Mendivil. Revision de Jose Luis Lopez de Lizaga, Madrid: Trotta, 2016, 172 p.
2022-02-08T16:37:24.635Z
89,278,170
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.15578/MA.4.1.2009.40-44", "MAG": "2528154893", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Survai keramba jaring tancap ikan bandeng ( Chanos chanos ) menjadi suatu studi yang menarik dibandingkan dengan daerah lain karena kegiatan dilakukan di muara sungai yang mengalami perkembangan sangat cepat, dimana pada awalnya bermula dengan 2 keramba sebagai percobaan, ternyata dalam kurun waktu 6 bulan sudah menutupi semua areal sungai sepanjang sekitar 4 km dengan 310 buah keramba. Kegiatan ini perlu menjadi perhatian Pemda setempat karena pada satu sisi kegiatan ini jelas akan meningkatkan produksi ikan dan meningkatkan pendapatan nelayan namun di lain hal kecepatan pertambahan jumlah keramba di luar batas daya dukung perairan, akan mendatangkan suatu risiko yang tinggi bagi keberhasilan kegiatan tersebut, bahkan dapat menyebabkan kematian total seperti yang sudah terjadi pada daerah-daerah lain, seperti di Waduk Cirata, Danau Maninjau, dan daerah lainnya.
2022-02-10T19:49:05.847Z
17,834,043
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/PESW.2000.847650", "MAG": "2097023746", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This paper presents our co-operative hybrid algorithm for fault diagnosis in power transmission networks. When a fault occurs in a transmission network, it must be identified and eliminated as soon as possible. Since control centers are flooded with hundreds of alarm messages during a fault, fault diagnosis, which involves the analysis of alarm messages, is a time consuming task. Towards the development of a fault diagnostician, model-based, heuristic, and neural networks are applied to the domain and the results are presented in this paper. The algorithm is a hierarchical model which combines several reasoning methods such as heuristic, temporal and model-based diagnosis and incorporates a network of neural networks at one of the levels of the hierarchy. The working of this co-operative algorithm is discussed and its results are analysed.
2022-09-06T03:33:02.704Z
59,226,506
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1037/ort0000399", "MAG": "2911755620", "PubMedCentral": null }, "license": null, "status": "GREEN", "url": "https://europepmc.org/articles/pmc6656633?pdf=render" }
Poor neurocognitive functioning among individuals with schizophrenia is typically conceptualized as resulting from a disease process. The objective of this article is to further expand understanding of poor neurocognition beyond pathogenesis toward a perspective that also incorporates community participation factors. This article focuses on three such factors-sedentary behavior, loneliness, and poverty-that have been demonstrated to be related to neurocognition and are highly prevalent among individuals with schizophrenia. This article provides an overview of the research on each factor and discusses its possible connection to neurocognitive challenges for individuals with schizophrenia. Implications for research, policy, and practice efforts are then proposed to broaden approaches to understanding and addressing neurocognitive challenges in this population. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
2022-09-06T19:51:51.882Z
121,232,584
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3934/JIMO.2014.10.701", "MAG": "2049718060", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Vehicle routing problem is a classic combinational optimization problem, which has been attracting research attentions in logistics and optimization area. Conventional static vehicle routing problem assumes the logistics information is accurate and timely, and does not take into account the uncertainties, which is therefore inadequate during practical applications. In this paper, a vehicle initial routing optimization model considering uncertainties is proposed, the vehicle capacity, customer time-window, and the maximum travelling distance as well as the road capacity are considered. In the cyber-physical logistics system background, a routing adjustment model is proposed to minimize the total distribution cost considering the road congestion, and the static and dynamic models are proposed for traffic information transmission network to quantitatively analyse the impact of the traffic information transmission delay on the vehicle routing optimization. The learnable genetic algorithm is adopted to solve the initial routing optimization model and the routing adjustment model. The simulation results have verified its effectiveness.
2022-10-06T06:08:30.597Z
6,705,455
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/03610911003624875", "MAG": "2077888756", "PubMedCentral": null }, "license": null, "status": null, "url": null }
An alternative graphical method, called the SSR plot, is proposed for use with a multiple regression model. The new method uses the fact that the sum of squares for regression (SSR) of two explanatory variables can be partitioned into the SSR of one variable and the increment in SSR due to the addition of the second variable. The SSR plot represents each explanatory variable as a vector in a half circle. Our proposed SSR plot explains that the explanatory variables corresponding to the vectors located closer to the horizontal axis have stronger effects on the response variable. Furthermore, for a regression model with two explanatory variables, the magnitude of the angle between two vectors can be used to identify suppression.
2022-11-13T00:20:32.782Z
59,224,035
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2147/CCIDE.S190230", "MAG": "2909435958", "PubMedCentral": "6338237" }, "license": null, "status": null, "url": null }
Purpose This study was designed to establish normal values for the nasal form and its relationship to the other cranial structures among male and female skeletal class I Saudi adults. The results of males and females were compared to each other and to the results of a previous study using the same analysis method. Patients and methods Sixty-two lateral cephalometric radiographs of Saudi subjects (32 females and 30 males) were retrospectively retrieved from the orthodontic clinical data. Their ages ranged from 20 to 24 years old. All of the cephalometric radiographs were traced manually. Results There were statistically significant differences between the Saudi males and females in the nasal length, nasolabial angle, horizontal distance from the nose tip to the incisal edge of the most prominent upper central incisor, and chin. The Saudi males had longer dorsa and increased vertical distances from the pronasale to the chin when compared to the females. The Saudi females had longer vertical distances from the pronasale to the upper lip and larger nasolabial angles when compared to the males. The Saudi males and females had longer noses, longer dorsa, more curved noses (larger supratip break angles), and increased horizontal distances between the nose tip and the chin when compared to a New Zealand sample. The New Zealand sample had increased nasolabial angles, increased nasal tip projection angles, noses significantly projected from the upper lip, the most prominent central incisors, and more prominent maxillae when compared to the Saudi sample. Conclusion There were significant differences between the Saudi males and females, as well as between the Saudi sample and the New Zealand sample. These results suggest that both gender and ethnicity must be taken into account when establishing normal values for the nasal form and its relationship to the other cranial structures.
2022-12-10T08:36:08.867Z
6,000,260
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/02652040310001637893", "MAG": "1976601849", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Eudragit RS microspheres containing verapamil HCl for oral use were prepared using three different dispersing agents: aluminium tristearate, magnesium stearate and sucrose stearate, by a solvent evaporation method. The effects of the type and concentration of the dispersing agents and the inner phase polymer concentration on the size and T63.2% (the time at which 63.2% of the drug is released) of microspheres were determined by multiple linear regression analysis. The morphology of microspheres was characterized by scanning electron microscopy. The surface of microspheres prepared with sucrose stearate was smoother and non-porous and the drug release from these microspheres was the fastest. When aluminium tristearate or magnesium stearate were used as dispersing agents, the particle size of microspheres became smaller. Increasing amounts of these two dispersing agents led to the accumulation of their free particles onto the surfaces of the microspheres. The drug release from the microspheres was slower than that of the microspheres from sucrose stearate depending on their hydrophobic structures. According to the results of the multiple linear regression analysis among the dispersing agents used, aluminium tristearate showed the best correlation between the examined input (dispersing agent and polymer concentrations) and output (T63.2% and particle size) variables.
2022-12-13T07:43:37.612Z
24,589,184
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1111/j.1751-553X.2011.01298.x", "MAG": "1936066469", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Introduction:  We determined the utility of leukocyte cell population data (CPD) for the screening of sepsis and fungemia.
2022-12-14T20:02:38.705Z
135,338,305
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.26502/AVSM.003", "MAG": "2905914262", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This is a review article to document the available literature on the effects of non-genetic factors on productive and reproductive traits of indigenous goats in Nepal. The review included journal articles, published reports, technical bulletins, post-graduate and doctoral dissertation. Scientific information regarding the factors affecting the productive and reproductive performance of goats is important in relation to developing the production and productivity improvement plans. This is a review article to document available literature one present study aims at reviewing the effects of non-genetic factors on productive and reproductive traits of indigenous goats in Nepal. The review included study was based on the review of available scientific literature including research journal articles, published reports, technical bulletins, post-graduate and doctoral dissertation. The study revealed that showed that altitude, season of conception, season of kidding, number of kids at birth, parity, size of doe are the major factors affecting productive and reproductive traits of indigenous goats of Nepal. These factors should be carefully, and such factors must be considered carefully to promote the indigenous goat production in commercial scale farming level.
2022-12-17T13:29:38.432Z
44,994,357
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/14672710122284", "MAG": "2085075441", "PubMedCentral": null }, "license": null, "status": null, "url": null }
In September 1995 relations between the United States, Japan, and Okinawa were transformed when three U.S. servicemen brutally gang-raped a twelve-year-old schoolgirl. Okinawan feminists called public attention to the rape, but it wasn't long before the media and political leaders shifted their focus to concerns about Okinawa's colonial history and its postwar occupation by the United States. A crisis of sovereignty replaced the crisis for women and a particular girl, which gradually faded from view, as did the agenda of feminist activists. Through an examination of Okinawa's contentious identity politics, the author traces the political trajectories of Okinawa's component groups and asks why this particular crime, in a long list of crimes against Okinawans by U.S. personnel since 1945, resonates so strongly both in Okinawa and in mainland Japan. The author argues that the rape has been enlisted for its powerful symbolic capacity: Okinawa as sacrificed schoolgirl/daughter. As such it is emblematic of past, prior narratives of Okinawan victimhood, most notably the Himeyuri students in the Battle of Okinawa. Feminists' cooperation in a patriarchal language that posits Okinawa as daughter within a national Japanese family is problematic but necessary as a strategy in the fight for women's human rights.
2022-12-18T18:49:54.918Z
244,365,239
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/19452829.2021.2004096", "MAG": null, "PubMedCentral": null }, "license": "CCBYNCND", "status": "HYBRID", "url": "https://www.tandfonline.com/doi/pdf/10.1080/19452829.2021.2004096?needAccess=true" }
ABSTRACT This article has sought to explain a research process where a senior researcher felt the need to form an alliance with local researchers in order to enable more authentic research with marginalised youngsters. The aim of this paper is to suggest a useful model demonstrating the focal role of the primary investigator in creating an inclusive and participatory setting to produce knowledge challenging epistemic injustices. By cooperating with novice researchers in the countries we study, our methodology recognised and fostered their epistemic agency. As knowledge mediators, they helped us access many self-identified Muslim youth and native youths who are labelled as far-right in Europe. In addition to emphasising the relevance of local setting in knowledge production, the paper will also question the epistemic injustice that these youngsters have been exposed to. Both groups have been clustered in two distinct categories by previous research that has been overwhelmingly engaged in the civilisational discourse that sets these groups apart in two culturally, religiously and civilisationally defined boxes. We believe that our participatory commitment to producing high-quality knowledge will be helpful in the scientific consideration of socio-economically, politically, spatially, and nostalgically deprived youths, who feel pressurised by the perils of modernisation and globalisation.
2022-12-25T16:40:25.891Z
233,282,364
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.5802/CRCHIM.58", "MAG": "3127746117", "PubMedCentral": null }, "license": null, "status": null, "url": null }
In this article, the synthesis of biocompatible fibrous scaffolds with antimicrobial properties based on polycaprolactone/hydroxyapatite/amoxicillin and study of their surface morphology, antimicrobial effect, and drug release are discussed. Hydroxyapatite (1–2 μm, 97%) synthesized from biologically waste material (eggshell) was added to the composite scaffolds as a bone-replacement material. The scaffolds’ antimicrobial properties were evaluated against S. aureus and E. faecalis. The scaffolds possessed a sustained drug release from the scaffolds amounted to about 94% of the antibiotic’s total weight over a 4-week observation period. Agar diffusion confirmed the antimicrobial properties of the scaffolds against specific bacteria.
2022-12-23T02:23:50.502Z
15,509,497
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/DTIS.2012.6232973", "MAG": "1992915588", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Current VLSI systems-on-Chips (SoCs) integrate billions of transistors and are clocked with multi-gigahertz clock frequencies. As the geometrical dimensions of both devices and wires in theses systems become smaller, the internal communication performance between the SoC's blocks is heavily affected by the on-chip interconnect wire delays. In this paper, we propose a high efficient mesochronous outfit for network on chip (NoC) interconnects retiming. The proposed solution resolves the problem of clock skew and signal delays by using a delay locked loop (DLL) and a strobe signal to gauge the phase difference between two clock domains in a SoC. The asynchronism problem in the system is avoided by a data retiming accomplished by delaying signals with the mean of controllable delay buffers. The outfit foster alleviates the system's design complexity and results in a significant gain in their performances. The proposed device was implemented in 250 nm process technology and simulated for the worst case conditions using Tanner tool. Under a 3.3 V power supply and synched with a 800 MHz clock, the synchronizer consumes about 33.4 mW per bitline at room temperature.
2022-02-13T01:55:32.746Z
39,383,106
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1093/AJCP/72.6.893", "MAG": "2318879736", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Sera from 12 multitransfused patients who were refractory to random-donor platelets were tested for lymphocytotoxic and leukoagglutinating antibodies using panel cells from various volunteers whose HLA-A and -B antigens were known. All sera contained leukoagglutinins reactive with cells from at least one panel member, whereas only 33% had lymphocytotoxic antibodies. Patients whose sera reacted frequently with panel cells using the microcapillary agglutination technic seldom responded to HLA-matched paltelets, whereas those whose sera reacted infrequently usually responded satisfactorily. It is concluded that non-HLA antibodies may play a significant role in determining the responses to platelet transfusions in multi-transfused patients.
2022-02-12T05:18:21.351Z
97,517,155
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1154/1.2951781", "MAG": "2093802140", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The sample was polished and positioned under the focused ion beam (FIB). The FIB principle is similar to the more conventional SEM with the exception that heavy gallium ions are used instead of electrons to bombard the metal surface. The FIB was used in this work both as a micro-milling and as imaging tool. The sample was positioned normal to the incipient ion beam. Initial surface preparation involved uniform exposure to the beam (socalled etching) to remove the oxide layer. A very useful side effect of etching is that it reveals identifiable surface features. After etching an image of the initial surface was taken with FIB. Then FIB milling was done normal to the sample surface which produced a 12x1x3.5 micron (length x width x depth) slot in the first experiment and a 20x1.5x6.5 micron slot in the second experiment. Finally the second image of the sample surface, capturing surface relaxation due to slotting, was registered with FIB. After that the slot profile was measured with a second cut across the slot.
2022-07-15T05:18:35.466Z
244,999,777
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.13130/CROSS-15342", "MAG": "3163526627", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This research is linked to studies on the criminal mobility of the 'ndrangheta in Australia. Starting from extensive research in the field, and from a critique of the concept of ethnicity and its links with organised crime in Australia, this work reflects on the political interests of the Calabrian clans in Australia. Some clans can maintain ties with powers and professional elites also by exploiting "ethnic solidarity” within the migrant community.
2022-09-13T00:47:04.160Z
8,205,861
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1042/BSR20090081", "MAG": "2097076294", "PubMedCentral": null }, "license": null, "status": null, "url": null }
ABC transporter (ATP-binding-cassette transporter) proteins have been strongly associated with the phenomenon of multidrug resistance in cancer cells. Furthermore, their physiological expression has been studied in many organisms, including bacteria, fungi, plants and vertebrate or invertebrate animals. Their widespread expression through the evolution demonstrates their relevance to the survival of living things. In the present study, we characterized the functional activity of ABCB1 and ABCC1 proteins in gametes and embryonic cells of the sea urchin Echinometra lucunter. The ABC transporter proteins' functional activity was up-regulated post-fertilization. Eggs and spermatozoa of E. lucunter accumulated more C-AM (calcein acetoxymethyl ester), a fluorescent substrate of ABCB1 and ABCC1 proteins, than embryonic cells. Verapamil, reversin 205 and indomethacin were able to increase C-AM influx in eggs and embryos. However, verapamil and reversin 205 were more efficient than indomethacin, suggesting a predominance of ABCB1 protein over ABCC1 protein activity. Multidrug resistance modulating agents, at the concentration range that inhibited ABC transporter proteins, did not block the embryonic development until blastula stage. However, inhibition of ABCB1-mediated efflux by reversin 205 circumvented resistance of embryos to the antimitotic vinca alkaloid vinblastine. Embryonic development was more efficiently blocked when colchicine was previously added to eggs than to embryos 5 min after fertilization. This set of results suggests that these proteins act as a fundamental biochemical barrier conferring a protective physiological role against toxic xenobiotics in E. lucunter embryos.
2022-12-02T10:26:08.578Z
25,347,231
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1111/J.1748-1716.1988.TB08321.X", "MAG": "2045838656", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The study pertains to a series of investigations on the effects of CO2 inhalation as used for pre-slaughter anaesthesia in swine. Acid/base parameters, blood oxygen tension, plasma Na, K, Ca and stress hormone concentrations were monitored in Yorkshire swine before, during, and for 10 min after the animals were descended for 1 min into 80% CO2 in air. Severe respiratory acidosis (PaCO2 approximately 50 kPa, arterial pH approximately 6.6) and hypoxia (PaO2 approximately 4kPa) had developed after 45 s of the CO2 inhalation. The corresponding changes in venous blood were less drastic (PvCO2 approximately 17 kPa, pH 7.1, PvO2 approximately 4 kPa). Readjustment to PaCO2 approximately II kPa, arterial pH 7.2, and PaO2 approximately 13 kPa had occurred at 1 min post CO2. Four minutes later the respiratory acidosis had become converted into metabolic acidosis subjected to partial respiratory compensation (arterial pH 7.3 in the presence of moderate hypocapnia and hyperoxaemia). The cause of this metabolic acidosis (present also at 10 min post CO2) was apparently hypoxia-induced anaerobic metabolism (= lactic acid production). Apparently due to hydrogen ion transport into the cells in exchange for other cations, hyperkalaemia (K approximately 6.6 mmol l-1), and a 7 mmol l-1 increase in plasma Na had developed at 1.5 min later. The CO2 inhalation did not change the total plasma Ca significantly. The transport of the swine from the stable to the immediate pre-experimental situation induced a 3-fold increase in plasma cortisol concentration (PC, to approximately 130 mmol l-1). No further increase in PC occurred in response to the CO2 inhalation. It indicates that no additional emotional strain was imposed upon the animals during the CO2 exposure.(ABSTRACT TRUNCATED AT 250 WORDS)
2022-12-16T06:08:49.156Z
157,060,471
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2312/egs.20191002", "MAG": "2947613882", "PubMedCentral": null }, "license": null, "status": null, "url": null }
We propose a novel approach to create generative models for distinctive stylistic locomotion synthesis. The approach is inspired by the observation that human styles can be easily distinguished from a few examples. However, learning a generative model for natural human motions which display huge amounts of variations and randomness would require a lot of training data. Furthermore, it would require considerable efforts to create such a large motion database for each style. We propose a generative model to combine the large variation in a neutral motion database and style information from a limited number of examples. We formulate the stylistic motion modeling task as a conditional distribution learning problem. Style transfer is implicitly applied during the model learning process. A conditional variational autoencoder (CVAE) is applied to learn the distribution and stylistic examples are used as constraints. We demonstrate that our approach can generate any number of natural-looking human motions with a similar style to the target given a few style examples and a neutral motion database. CCS Concepts • Computing methodologies → Animation; Motion processing;
2022-12-16T12:44:32.603Z
46,257,209
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/14616739900134161", "MAG": "1991807438", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The concept of organization in the service of adaptation has been applied to attachment theory (Sroufe & Waters, 1977) as well as to a variety of life sciences (Ryan, Kuhi & Deci, 1997). Internal working models (IWMs) are postulated as providing organizing structure to the attachment behavior system controlling attachment behaviors toward caregivers and, with increasing age, autonomous individual adaptation. While many theoretical specifications have been suggested on that topic (e.g. Bretherton, 1987, 1990; Bretherton & Munholland, 1999; Main, Kaplan & Cassidy, 1985; Sroufe & Fleeson, 1986), empirical studies focusing directly on the structure or functions of internal working models are rare. Knowledge about the structure and functioning of IWMs could add to the understanding of the developmental influences of the attachment organization across the life-span. In this paper two topics will be addressed shortly and related to an empirical investigation concerning the relationship between attachment representations during late adolescence and emotion regulation patterns: (1) structure and functions of IWMs in terms of information-processing and emotion and behavior regulation; and (2) the transfer from IWMs of self-with-attachment figures to adaptive personality structures based on autonomous self-regulation.
2022-12-18T10:56:04.911Z
123,345,727
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1002/NUM.10077", "MAG": "2125073032", "PubMedCentral": null }, "license": null, "status": null, "url": null }
We analyze a mixed finite element discretization of a second‐order quasilinear problem based on the Raviart‐Thomas space. We prove that the discrete problem is solvable and provide a local uniqueness result for the solution. We also obtain optimal order L2‐error estimates for both the scalar variable and the associated flux. The main feature of our method is that it is free from the boundness conditions required in previous works on the coefficients of the quasilinear operator. © 2003 Wiley Periodicals, Inc. Numer Methods Partial Differential Eq 20: 90–103, 2004.
2022-12-18T10:57:10.795Z
8,143,462
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1242/jeb.000141", "MAG": "2099928904", "PubMedCentral": null }, "license": null, "status": "CLOSED", "url": null }
SUMMARY All organisms are adapted to well-defined extracellular salinity ranges. Osmoregulatory mechanisms spanning all levels of biological organization, from molecules to behavior, are central to salinity adaptation. Functional genomics and proteomics approaches represent powerful tools for gaining insight into the molecular basis of salinity adaptation and euryhalinity in animals. In this review, we discuss our experience in applying such tools to so-called `non-model' species, including euryhaline animals that are well-suited for studies of salinity adaptation. Suppression subtractive hybridization, RACE-PCR and mass spectrometry-driven proteomics can be used to identify genes and proteins involved in salinity adaptation or other environmental stress responses in tilapia, sharks and sponges. For protein identification in non-model species, algorithms based on sequence homology searches such as MSBLASTP2 are most powerful. Subsequent gene ontology and pathway analysis can then utilize sets of identified genes and proteins for modeling molecular mechanisms of environmental adaptation. Current limitations for proteomics in non-model species can be overcome by improving sequence coverage, N- and C-terminal sequencing and analysis of intact proteins. Dependence on information about biochemical pathways and gene ontology databases for model species represents a more severe barrier for work with non-model species. To minimize such dependence, focusing on a single biological process (rather than attempting to describe the system as a whole) is key when applying `omics' approaches to non-model organisms.
2022-12-29T15:30:01.325Z
44,973,319
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1055/s-0034-1543967", "MAG": "2092322299", "PubMedCentral": null }, "license": null, "status": "GREEN", "url": "https://europepmc.org/articles/pmc4569499?pdf=render" }
Objective Varying types of clinicoradiologic presentations at the craniovertebral junction (CVJ) influence the decision process for occipitocervical fusion (OCF) surgery. We discuss the operative techniques and decision-making process in OCF surgery based on our clinical experience and a literature review. Material and Methods A total of 49 consecutive patients who underwent OCF participated in the study. Sagittal computed tomography images were used to illustrate and measure radiologic parameters. We measured Wackenheim clivus baseline (WCB), clivus-canal angle (CCA), atlantodental distance (ADD), and Powers ratio (PR) in all the patients. Results Clinical improvement on Nurick grading was recorded in 36 patients. Patients with better preoperative status (Nurick grades 1-3) had better functional outcomes after the surgery (p = 0.077). Restoration of WCB, CCA, ADD, and PR parameters following the surgery was noted in 39.2%, 34.6%, 77.4%, and 63.3% of the patients, respectively. Complications included deep wound infections (n = 2), pseudoarthrosis (n = 2), and deaths (n = 4). Conclusion Conventional wire-based constructs are superseded by more rigid screw-based designs. Odontoidectomy is associated with a high incidence of perioperative complications. The advent of newer implants and reduction techniques around the CVJ has obviated the need for this procedure in most patients.
2022-12-29T17:53:29.960Z
120,071,366
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1086/168274", "MAG": "2000662659", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The effects of radiation shear stresses acting in accretion disks and boundary layers are considered. It is demonstrated that these stresses are dynamically unimportant for nonrelativistic flows. For accretion onto a black hole or nonmagnetic neutron star, where the system is relativistic, radiation shear stresses can contribute substantially to the total luminosity of the system. The spectral and temporal signatures of this form of heating are discussed, and those features which are unique to radiative dissipation are emphasized. The results are in broad agreement with the spectra of the nonmagnetic X-ray binary systems, including Cyg X-1. 19 refs.
2022-02-09T22:31:49.111Z
208,766,440
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1177/030802265902201012", "MAG": null, "PubMedCentral": null }, "license": null, "status": null, "url": null }
Occupational therapy has been defined as "any activity, mental or physical, medically prescribed and professionally guided to aid a patient in recovery from disease or injury," by Willard and Spackman. This is a wide field to cover and to do this, an occupational therapist must be a psychiatrist, psychologist, physiotherapist, school teacher, social worker, friend, confidant and alternate mother. It is a great credit to the occupational therapists that they have succeeded in such a complex role. Working in a Children's Hospital the occupational therapist finds that the problems are more complicated than those of an adult hospital. Here, we are dealing with a child who is growing, developing and changing. She requires, as a result, a detailed knowledge of the normal growth and development of children and a knowledge of the various levels of achievement. When accidents or illness strike, the child is removed from all that is familiar and loved. He is thrust into a strange environment where everyone wears a peculiar uniform the doctors and nurses in white, the therapists in green. and ward aids in red. Add to this, fear of pain, fear of permanent separation from the parents, and we have all the ingredients necessary for a nervous breakdown. Fortunately this rarely happens due to the tremendous efforts of the hospital staff. Now an acute illness is mainly of interest to the nurses and paediatricians until the convalescent stage is reached. Then it is essential for the occupational therapist to re-awaken the spark of interest in the child. Left alone, the child tends to revert to the infantile development state and focuses attention on hIS own self. We see many examples of this, where a child previously trained, starts to bedwet until the occupational therapist gets working on him. The answer, of course, lies in play therapy and limited recreational therapy, for play occupies the major part of a younger child's time. Let us look into War Memorial Children's Hospital. The "full bed care" patients are visited daily by our occupational therapist when convalescent and given leather work, shell work, painting or some other quiet, recreational type of work tailored to their age. This gets the patient's interest focussed outward. He is made to feel at home and experiences a feeling of successful accomplishment. It must be remembered that the natural drive of a child is for appreciation and approval. As a result, children may he led but never pushed. Once the child's attention is focussed outward, the next step is socialization. In our hospital this is symbolized by the electric train room. It is fascinating to watch the interest awaken in a small boy's eyes, for here is a small boy's dream come true: a miniature railroad with streamliners, freight cars and yards. it is difficult to keep the internes at work when the railroad is operating. As the patients become more mobilized they can be moved to the occupational therapy department where more complicated equipment and materials allow more progressive training. On our circus roof similar group activities can be provided when the weather is good. All these procedures sound rather complicated and serious, for in an adult hospital they are regarded soberly. Yet Children's Hospitals are happy places, reflecting the personalities of paediatricians, paediatric nurses, therapists and all those persons involved in child care. Among these, the watchwords are enthusiasm, optimism and cheerfulness. The above compose the main functions
2022-07-09T03:45:27.869Z
127,860,404
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1017/CBO9780511844478.005", "MAG": "952390332", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Internal waters, territorial seas, international straits and archipelagic waters are marine spaces under the territorial sovereignty of the coastal State. However, the use of the marine environment for sea communication necessitates the freedom of navigation through those spaces. Consequently, marine spaces under territorial sovereignty are part of the territory of the coastal State and the highway for sea communication at the same time. The dual nature of marine spaces gives rise to the fundamental question of how it is possible to reconcile the territorial sovereignty of the coastal State and the freedom of navigation. With that question as a backdrop, this chapter will examine the following issues in particular: What is the coastal State’s jurisdiction over foreign vessels in internal waters? How is it possible to reconcile the need to provide refuge for ships in distress and the protection of the offshore environment of the coastal State? What is the right of innocent passage? Do foreign warships enjoy the right of innocent passage through the territorial sea? What is the legal regime of international straits? What is the legal regime of archipelagic waters? What are the differences between the right of innocent passage, the right of transit passage and the right of archipelagic sea lane passage? Introduction This chapter will seek to examine rules of international law governing marine spaces under territorial sovereignty. In this regard, particular attention must be devoted to two issues with regard to the reconciliation between the territorial sovereignty of the coastal State and the freedom of navigation.
2022-07-29T12:01:47.722Z
8,255,921
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1210/ENDO-125-5-2439", "MAG": "2048763472", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Immunoreactive PRL (IR-PRL) has been identified in many areas of the rat brain. Using sodium dodecyl sulfate-polyacrylamide gel electrophoresis and Western blot analyses we have recently shown that the primary IR-PRL protein in the rat brain has an apparent mol wt (Mr) of 24,000, which was identical to that of pituitary PRL. In these studies, brain and pituitary 24,000 Mr PRL were compared by peptide mapping and lectin chromatography. PRL-enriched fractions were prepared from the pituitary, hypothalamus, hippocampus, and pons-medulla and labeled with 125I. This material was further purified by immunoprecipitation, and immunopurified 24,000 Mr PRL was isolated by sodium dodecyl sulfate-gel electrophoresis. Cleavage of 125I-labeled 24,000 Mr IR-PRL prepared from the pituitary and the three brain regions with chymotrypsin resulted in identical peptide maps with two primary labeled peptide fragments (5,500 and 6,000 Mr), and approximately five less intense fragments. Similarly, trypsin cleavage of brain and pituitary 24,000 Mr IR-PRL resulted in the production of two major fragments (6,200, and 5,200 Mr), and three less intense fragments. Cleavage of the 24,000 Mr IR-PRL with Staphylococcus V8 protease resulted in identical fragment patterns with two primary peptide fragments (14,000 and 6,200 Mr). When the pituitary and brain 24,000 Mr PRL were applied to Concanavalin-A-Sepharose columns no 24,000 Mr PRL was absorbed. The similarity of the peptide fragments obtained from the cleavage of the 24,000 Mr IR-PRL from the brain and pituitary clearly indicate that the IR-PRL found in the brain has an amino acid sequence that shares a high degree of structural homology with pituitary PRL.
2022-09-12T21:49:07.715Z
42,021,624
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/RADECS.2007.5205489", "MAG": "2166710635", "PubMedCentral": null }, "license": null, "status": null, "url": null }
A code solving most of the known physical processes conducting to the MOS degradation under total dose constraint has been developed. Two lots of a power MOSFET have been exposed to Co60 irradiations with various temperature and different bias conditions. The parameters used in the code have been adapted in order to fit the experimental results. According to the simulation results, the physical processes leading to the measured oxide trapped charge and interface traps dependencies are discussed. Different kinetics of degradation when switching the dose rate from high to low and the ELDRS are explained by the electric field inversion due to shallow trapped holes. An estimation of the very low dose rate degradation is done for devices sensitive to ELDRS.
2022-09-15T03:20:51.136Z
58,753,864
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.12968/AJMW.2015.9.2.77", "MAG": "1973045290", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Women's satisfaction with intrapartum care is critical as it may have a positive impact on service use. A descriptive cross-sectional study was conducted to describe women's level of satisfaction with delivery services in Komfo Anokye Teaching Hospital in Kumasi, Ghana. A total of 100 randomly selected postnatal women participated in the study using a semi-structured interview schedule. Data were collected over a 4-week period in March–April 2013 and were analysed using IBM SPSS Statistics 20. The results revealed that 62% of postnatal mothers were satisfied with delivery care. Although satisfaction level was high, respondents raised the issues of poor communication (44%), bad attitudes of midwives (24%) and sleeping on the floor (18%) as some of the general experiences they encountered on the labour ward. Women's satisfaction with delivery was related to doctors and midwives showing concern about respondents' labour pain, and the time service providers spent managing women's pain. Health care providers a...
2022-12-16T05:17:56.346Z
144,919,905
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1111/J.1475-682X.1987.TB01039.X", "MAG": "2073597082", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This essay articulates a comparative approach to the sociology of science. It suggests that even historically there have been numerous scholars interested in the national components of scientific knowledge. I develop a model which allows me to compare the differences in scientific growth in Sweden and Denmark. My model consists of three interrelated levels: metaphysical bias, national scientific interests, institutional structures. The comparison between the two countries shows them to be markedly different on all three levels. Finally, I suggest how the model can be applied to contemporary material.
2022-12-17T22:25:52.500Z
19,797,371
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1046/j.1526-4610.2002.02010.x", "MAG": "1990698167", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Background.—Migraine sufferers typically have been instructed to delay triptan therapy until headache intensity is at least moderate. Recent data suggest that earlier use of triptans may be more beneficial.
2022-12-19T10:32:01.838Z
12,782,129
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/ICIP.2000.899601", "MAG": "2155155237", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Texture is a very important image feature extremely used in various image processing problems. It has been shown that humans use some perceptual textural features to distinguish between textured images or regions. Some of the most important features are coarseness, contrast, direction and busyness. In this paper a new method based on the autocovariance function to estimate quantitatively these features is shown and the correspondence between these computational measures and the psychological ones made by human subjects is shown using some psychometric method.
2022-12-20T17:29:46.721Z
154,972,246
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1111/1467-9515.00249", "MAG": "2068822496", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This article examines deprivation among unemployed young people. It draws on a comparative survey of 8,654 young unemployed in Denmark, Finland, Iceland, Norway, Sweden and Scotland. In spite of an increased knowledge of the relationship between unemployment and poverty,our understanding of deprivation among young unemployed people remains inadequate. How do young people deal with unemployment? Are transitional factors the only explanation for the prevalence of deprivation or should we also consider intergenerational factors? The six countries represent two different welfare strategies, the Nordic universalistic model and the Scottish liberal/ minimalist approaches. The research findings showed diverging tendencies within the Nordic countries. Converging trends between the different systems could also be found, as family support plays the main role in preventing deprivation in all of the countries.
2022-12-24T20:40:41.909Z
226,222,143
{ "externalids": { "ACL": null, "ArXiv": "2010.16416", "DOI": "10.1051/0004-6361/202039805", "MAG": "3133177600", "PubMedCentral": null }, "license": null, "status": "BRONZE", "url": "https://www.aanda.org/articles/aa/pdf/2021/05/aa39805-20.pdf" }
We present constraints on extensions to the standard cosmological model of a spatially flat Universe governed by general relativity, a cosmological constant (Λ), and cold dark matter (CDM) by varying the spatial curvature ΩK, the sum of the neutrino masses ∑mν, the dark energy equation of state parameter w, and the Hu-Sawicki f(R) gravity fR0 parameter. With the combined 3 × 2 pt measurements of cosmic shear from the Kilo-Degree Survey (KiDS-1000), galaxy clustering from the Baryon Oscillation Spectroscopic Survey (BOSS), and galaxy-galaxy lensing from the overlap between KiDS-1000, BOSS, and the spectroscopic 2-degree Field Lensing Survey, we find results that are fully consistent with a flat ΛCDM model with ΩK = 0.011−0.057+0.054, ∑mν < 1.76 eV (95% CL), and w = −0.99−0.13+0.11. The fR0 parameter is unconstrained in our fully non-linear f(R) cosmic shear analysis. Considering three different model selection criteria, we find no clear preference for either the fiducial flat ΛCDM model or any of the considered extensions. In addition to extensions to the flat ΛCDM parameter space, we also explore restrictions to common subsets of the flat ΛCDM parameter space by fixing the amplitude of the primordial power spectrum to the Planck best-fit value, as well as adding external data from supernovae and lensing of the cosmic microwave background (CMB). Neither the beyond-ΛCDM models nor the imposed restrictions explored in this analysis are able to resolve the ∼3σ tension in S8 between the 3 × 2 pt constraints and the Planck temperature and polarisation data, with the exception of wCDM, where the S8 tension is resolved. The tension in the wCDM case persists, however, when considering the joint S8 − w parameter space. The joint flat ΛCDM CMB lensing and 3 × 2 pt analysis is found to yield tight constraints on Ωm = 0.307−0.013+0.008, σ8 = 0.769−0.010+0.022, and S8 = 0.779−0.013+0.013.
2023-01-01T17:51:47.736Z
87,486,545
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.3181/00379727-34-8549C", "MAG": "2328270911", "PubMedCentral": null }, "license": null, "status": null, "url": null }
It is known that methionine can replace cystine as a growth essential in the diet of rodents. 1 , 2 , 3 This report extends to the invertebrate marine hydroid Obelia geniculata the premise that this sulfur-containing amino acid is a growth stimulant. The purpose is to see whether lower as well as higher organisms can utilize — S — sulfur for growth purposes, and whether any particular phase of growth activity is responsive thereto, since this point is unsettled in work with rodents. Through the courtesy of Professor du Vigneaud we obtained enough dl-methionine for 32 experiments. In these the developmental growth of some 6000 animals in methionine cultures was compared with that of a like number in plain sea water. Description of the organism and its growth together with that of the experimental and other procedures is given in detail elsewhere. 4 , 5 Tests and controls were run simultaneously under like conditions of temperature, illumination, and pH. Results are tabulated as condensed consistency data from which is seen the trend of test deviation from control in expression of new growth initiation, proliferation, differentiation, and organization, as well as that for maintenance, regression, and catabolism. 6 The table also gives the concentrations used and the number of experiments, colonies, hydranths, and gonophores. Since general reaction was essentially the same in the stated concentrations the data were combined into one set of figures to save space. Those for the 6 experiments at M/50,000 and M/25,000 were omitted because they show nothing but toxicity.
2022-02-10T21:23:53.382Z
171,280,321
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1177/001258060812644203", "MAG": "2518785919", "PubMedCentral": null }, "license": null, "status": null, "url": null }
T HE English Benedictine liturgy symposium of 2006 was concerned with the 'Refonn of the Reform', and the participants heard an interesting paper from Dr Alcuin Reid/ which gave rise to a discussion about how particular changes in the Church's liturgy, especially since the Second Vatican Council, might be known to be either legitimate developments in the liturgy or rather corruptions, which Reid in his book on The Organic Development of the Liturgy variously attributes to unwarranted innovation, liturgical antiquarianism, expediency and a misplaced sense ofpastoral need, all of which subvert and corrupt what he terms 'objective liturgical Tradition'.' N ow, I am not a liturgist, and so do not really feel able to enter the debate about which liturgical changes are authentic and which are in need of some revision or even reversal. Nor do I intend to try to show that Reid is wrong in his analysis of liturgical change, but I would like to suggest that Newman's theory of development could be of some use to this general discussion, as it seems to me that it coheres quite well with the 'General Principles for the Restoration and Promotion of the Sacred Liturgy' set out in Sacrosanctum Concilium; and, furthermore, that it arguably allows for rather more widespread change than Reid would appear to be comfortable with though a detailed discussion of the two models of development would, of course, be the work of another paper.
2022-02-08T16:54:45.570Z
18,884,700
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/INDIN.2013.6889112", "MAG": "2148465067", "PubMedCentral": null }, "license": null, "status": null, "url": null }
In the SECRICOM project where seamless, interoperable crisis management communication is required, strong security and trust must be achieved under hostile physical and communication environment. Such environment centralized remote trusted third parties (TTP) are not easily deployed and can constitute single points of failure. In this paper, a local, distributed, attestation mechanism based on a smart card like hardware structure called Secure Docking Module (SDM) that is physically attached to each SECRICOM enabled communication device, is proposed. The SDM acts as an external security and trust arbiter attached to a host device that can provide secure storage and instill strong security and trust. In this paper, we elaborate on the above concept, present the SDM functionality and describe the necessary SDM hardware architecture and memory structure to realize this functionality. Our goal is to highlight the SDM usefulness as a local TTP capable of binding both user and its device to trust.
2022-02-12T23:33:09.242Z
41,710,193
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1002/pmic.201400036", "MAG": "2072182101", "PubMedCentral": null }, "license": null, "status": null, "url": null }
We here present GradientOptimizer, an intuitive, lightweight graphical user interface to design nonlinear gradients for separation of peptides by reversed‐phase liquid chromatography. The software allows to calculate three types of nonlinear gradients, each of them optimizing a certain retention time distribution of interest. GradientOptimizer is straightforward to use, requires minimum processing of the input files, and is supported under Windows, Linux, and OS X platforms. The software is open‐source and can be downloaded under an Apache 2.0 license at https://github.com/statisticalbiotechnology/NonlinearGradientsUI.
2022-12-10T21:23:43.930Z
54,576,776
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1590/1980-549720180010.supl.1", "MAG": "2902598150", "PubMedCentral": null }, "license": "CCBY", "status": "GOLD", "url": "http://www.scielo.br/pdf/rbepid/v21s1/en_1980-5497-rbepid-21-s1-e180010.pdf" }
OBJECTIVE To estimate the association between soft drink consumption and body mass index (BMI) in eutrophic and overweight adolescents. METHODS We used data from the National Adolescent Student Health Survey (Pesquisa Nacional de Saúde do Escolar - PeNSE) of 2009. The dependent variable (outcome) was the tertiles of BMI score (zBMI), and the main independent variable (exposure) was the consumption of sugar-sweetened soft drinks. The models included age, school type, home goods and services score, and maternal schooling as adjustment variables. We estimated the association between exposure and outcome by using multinomial regression models, stratified by gender, and eutrophic and overweight subgroups. RESULTS 23.8% of the adolescents evaluated were overweight, and 21.7% reported consuming soft drinks daily. For eutrophic boys, those who consumed soft drinks had a greater chance of being in higher zBMI tertiles than non-consumers. For overweight adolescents, both male and female, soft drink consumption was associated with a lower chance of being in the highest tertile of zBMI score. CONCLUSION The results show the possibility of reverse causality between consumption of sweetened soft drinks and zBMI in the overweight adolescents group. For eutrophic male adolescents, soft drink consumption can potentially increase the chances of having higher zBMI, which reinforces the need for measures to significantly reduce the consumption of this beverage.
2022-12-11T00:53:17.301Z
147,913,391
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1515/zfsoz-1988-0301", "MAG": "2404106438", "PubMedCentral": null }, "license": null, "status": "CLOSED", "url": null }
Zusammenfassung Die Erinnerung an Werk und Wirken von Hans Haferkamp († 1987) verweist nicht nur auf seine Beiträge zur soziologischen Handlungstheorie, sondern auch darauf, daß er ein ausgeprägt pragmatisches Verhältnis zu seinem wissenschaftlichen Handeln hatte. Was tun wir eigentlich, so wird im Gedenken an ihn gefragt, wenn wir Theorien bilden, Methoden entwickeln, Forschung betreiben? Welchen Denk- und Handlungszwängen unterliegen wir dabei, - ja stiften sie womöglich selbst? Ohne weitreichenden epistemologischen Anspruch werden aus diesem Anlaß und in dieser Richtung einige aktuelle Probleme professionellen Handelns in der Soziologie erörtert.
2022-12-12T03:21:23.593Z
225,507,849
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1080/0907676x.2020.1797132", "MAG": "3045955574", "PubMedCentral": null }, "license": null, "status": null, "url": null }
ABSTRACT Yuān (冤) is a Chinese word literally meaning ‘bent’ which translates into English as ‘injustice’, ‘wrong’ and ‘tort’. It realises various conceptual metaphors in Chinese, such as yuan is bent, yuan is dirty, and yuan is dark. How does the English translation change these conceptual metaphors and their reception by target text readers? This study takes a Descriptive Translation Studies approach to answer this question. First, it introduces the methods of retrieving and analysing linguistic data, such as corpus search, and the principle of Cognitive Equivalence. Second, it shows the metaphors that yuān realises in Chinese and those realised by its translations in English, and compares their legal meanings. This study has found that ‘injustice’, ‘wrong’ and ‘tort’ are bent, as yuān is, although ‘tort’ is fully lexicalised and does not activate this mapping in contemporary English. None of the translations for yuān maps dirtiness and darkness onto the corresponding abstract notions. The legal meanings of these words in the two languages are also significantly different.
2022-01-27T17:15:25.054Z
171,061,399
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1177/030908920102509308", "MAG": "2174086253", "PubMedCentral": null }, "license": null, "status": null, "url": null }
This article observes the interrelationship between Isa. 2.2–4, 5 and Mic. 4.1–5, but it eschews previous attempts to reconstruct the original or common form of the composition. Based upon an analysis of the unique formulations of these passages in relation to their respective literary contexts in Isaiah and Micah, it argues that each serves a unique religio-political agenda. Whereas Isa. 2.2–4 looks forward to an idyllic period of world peace in which Israel/Judah will join the nations in acknowledging Yhwh's sovereignty as part of the larger Persian empire, Mic. 4.1–5 looks forward to an era of world peace in which a righteous Davidic monarch will arise to punish the nations prior to acknowledgement of Yhwh's sovereignty. The different agendas in these texts point to a debate within earlier Persian-period Judah concerning the character of the restoration and Judah's relationship to the Persian empire.
2022-02-08T17:02:23.715Z
232,357,988
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.2478/geochr-2020-0040", "MAG": null, "PubMedCentral": null }, "license": "CCBYNCND", "status": "GOLD", "url": "https://www.sciendo.com/pdf/10.2478/geochr-2020-0040" }
Abstract To assess if the heat-treated E1′ centre in quartz is suitable for fluvial sediment provenance tracing, eight granitic samples from sediments and their source rocks with distinct geological ages and origins were collected for electron spin resonance (ESR) measurements. The results show that the maximum heat-treated E1′ signal intensity of quartz in the fluvial sediments occurs upon heating at about 300°C, as previously observed in aeolian quartz. The heat-treated E1′ signal intensity of quartz in sediment samples also shows significant correspondence to those of their source rocks as well as their formation age. We propose that the heat-treated E1′ centre of sedimentary quartz, combined with other lithological discrimination parameters, could serve as an effective indicator for fluvial sediment provenance tracing.
2022-09-02T03:22:24.032Z
236,745,194
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/TMAG.2021.3080292", "MAG": "3161224104", "PubMedCentral": null }, "license": null, "status": null, "url": null }
Flux switching motors (FSMs) with conventional stator slots have a relatively low copper slot filling factor. In this article, a new octane modular stator with pentagon-shaped slot electrically excited FSM (EEFSM) that has a comparatively higher copper slot filling factor is analyzed analytically to reduce computational complexity, high computational time, and high drive storage. The analytical results of the proposed EEFSM are validated via the finite element method. Furthermore, the initial design is optimized to improve the electromagnetic performance, and finally the prototype is fabricated and tested experimentally. There is good agreement among the analytical, finite element analysis (FEA), and experimental results with variations of 3%–5%. The average torque of the optimized design has improved by 30%, cogging torque is suppressed by 36%, and torque ripples have reduced by 38%, which have improved the performance of EEFSM in terms of low acoustic noise, low vibration, and longer motor lifetime. The proposed octane modular stator can be easily unfolded for windings maintenance, coils placement, and motor transportation in case of large-size applications.
2022-11-12T16:46:15.420Z
73,580,268
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1029/2010GL043671", "MAG": "2795833252", "PubMedCentral": null }, "license": null, "status": null, "url": null }
We use global‐average thermospheric total mass density, derived from the drag effect on the orbits of many space objects, to study the behavior of the thermosphere during the prolonged minimum in solar activity between cycles 23 and 24. During 2007–2009 thermospheric densities at a fiducial altitude of 400 km were the lowest observed in the 43‐year database, and were anomalously low, by 10–30%, compared with climatologically expected levels. The density anomalies appear to have commenced before 2006, well before the cycle 23/24 minimum, and are larger than expected from enhanced thermospheric cooling by increasing concentrations of CO2. The height dependence of the mass density anomalies suggests that they are attributable to a combination of lower‐than‐expected exospheric temperature (−14 K) and reductions in the number density of atomic oxygen (−12%) and other species (−3%) near the base of the diffusive portion of the thermosphere.
2022-12-28T15:09:04.336Z
245,834,668
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.26490/uncp.prospectivauniversitaria.2013.10.26", "MAG": null, "PubMedCentral": null }, "license": "CCBYNCSA", "status": "GOLD", "url": "https://revistas.uncp.edu.pe/index.php/prospectiva/article/download/26/24" }
Objetivo: Evaluar la calidad del agua del río Cunas mediante índices fisicoquímicos y biológicos a fin de identificar las zonas con buen estado de conservación, entre enero y diciembre de 2013. Métodos: Se utilizaron los métodos de observación, descripción y explicación, el diseño no experimental de tipo longitudinal. Se definieron tres sectores de muestreo, en Angasmayo (Concepción), Huarisca (Chupaca) y Pilcomayo (Huancayo). Las muestras de agua fueron colectadas en botellas de plástico de dos litros y en frascos de vidrio estériles para determinar la concentración de nitratos y fosfatos, y coliformes termotolerantes, respectivamente. Los parámetros medidos in situ fueron: oxígeno disuelto (mg/l), sólidos totales disueltos (mg/l), temperatura (°C), pH y turbidez (FTU). Estas mediciones se realizaron con equipos portátiles Hanna Instruments. Las muestras de macroinvertebrados bentónicos se colectaron mediante una red Surber con malla de 250 μm de abertura. Resultados: según el INSF, Angasmayo presentó calidad de agua buena (75,14 en época de lluvia; 74,23 en estiaje), Huarisca calidad media (67,96 en lluvia; 65,22, en estiaje) y Pilcomayo calidad media (61,39 en lluvia; 55,82 en estiaje). Según el índice EPT, Angasmayo reveló buena calidad de agua, Huarisca regular calidad y Pilcomayo mala calidad de agua. Conclusiones: En Angasmayo, las masas de agua tanto en época de lluvia como en estiaje calificaron como agua de calidad buena. En Huarisca calificaron como agua de calidad media o regular y en Pilcomayo, como agua de calidad media (según INSF) y de calidad mala (según EPT).
2022-12-30T00:47:37.682Z
10,537,514
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1029/2004JD004949", "MAG": "2006682547", "PubMedCentral": null }, "license": null, "status": null, "url": null }
[1] Methods to detect tropical deep convective clouds and convective overshooting from measurements at the three water vapor channels (183.3 ± 1, 183.3 ± 3, and 183.3 ± 7 GHz) of the Advanced Microwave Sounding Unit-B (AMSU-B) are presented. Thresholds for the brightness temperature differences between the three channels are suggested as criterion to detect deep convective clouds, and an order relation between the differences is used to detect convective overshooting. The procedure is based on an investigation of the influence of deep convective cloud systems on the microwave brightness temperatures at frequencies from 89 to 220 GHz using simultaneous aircraft microwave and radar measurements over two tropical deep convective cloud systems, taken during the Tropical Rainfall Measuring Mission (TRMM) Large Scale Biosphere-Atmosphere Experiment (LBA) campaign. Two other aircraft cases with deep convective cloud systems observed during the Third Convection and Moisture Experiment (CAMEX-3) are used to validate the criteria. Furthermore, a microwave radiative transfer model and simulated mature tropical squall line data derived from the Goddard Cumulus Ensemble (GCE) model are used to validate the procedures and to adapt the criteria to the varying viewing angle of AMSU-B. These methods are employed to investigate the distributions of deep convective clouds and convective overshooting in the tropics (30°S to 30°N) for the four 3-month seasons from March 2003 to February 2004 using the AMSU-B data from NOAA-15, -16, and -17. The distributions show a seasonal variability of shifting from the winter hemisphere to the summer hemisphere. The distributions of deep convective clouds follow the seasonal patterns of the surface rainfall rates. The deep convective clouds over land penetrate more frequently into the tropical tropopause layer than those over ocean. The averaged deep convective cloud fraction is about 0.3% in the tropics, and convective overshooting contributes about 26% to this.
2022-12-30T18:58:03.352Z
21,004,613
{ "externalids": { "ACL": null, "ArXiv": null, "DOI": "10.1109/IGARSS.2014.6947667", "MAG": "1987001743", "PubMedCentral": null }, "license": null, "status": null, "url": null }
The development of satellite ground processing systems typically involves the creation of a custom-built platform for each new mission. As these systems are being developed, scientific algorithms must be implemented or re-engineered to work with both the software interfaces and the operational protocols of the ground processing environment. These activities introduce significant development overhead that is tangential to the product generation aspects of the system. This work presents a software architecture for the creation of operational data processing systems by configuring existing elements of a multi-mission scientific algorithm library. This library is comprised of algorithms and tools used to monitor, document, execute, and export structured data from those algorithms. Using this library of specially-developed multi-mission algorithms, the resulting systems are able to keep a tight loop between research and operational code and easily leverage existing effort. This results in reduced overhead and risk, and increases flexibility in the final system.
2022-02-12T21:36:25.263Z