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9,815,366 |
{
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"DOI": "10.3168/jds.2012-5450",
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"url": "http://www.journalofdairyscience.org/article/S0022030212006169/pdf"
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|
The objectives of this study were to (1) differentiate mixtures of a co-product blend (70:30% mixture of wheat:corn before bioethanol fermentation) from bioethanol processing with barley grain based on Fourier transform infrared attenuated total reflection molecular spectroscopy with cluster analysis, (2) elucidate the effects of the co-product blend on the molecular structure spectral profile and nutritive characteristics of the hull-less barley carbohydrate (CHO) in dairy cattle, and (3) quantify the relationship between the CHO molecular structure spectral profiles and CHO nutritive characteristics of the mixtures in dairy cattle. The parameters assessed for CHO molecular structure spectral profiles included molecular spectral peak area and height intensities of lignin, structural CHO (STCHO), cellulosic compounds, and total CHO. The parameters assessed for CHO nutritive characteristics included the CHO nutrient profiles, CHO subfractions, energy values, and rumen-fermentable organic matter supply. Hull-less barley grains and the co-product blend were mixed according to the ratio of 100:0 (B100), 75:25, 50:50, 25:75, and 0:100 (BD100). The results showed that when the co-product blend was included at the different ratios, the predicted rumen-fermentable organic matter supply in the rumen was significantly decreased from 632 (B100) to 518 g/kg of dry matter (DM; BD100). The effective degradable dry matter in the rumen and the effective degradable starch in the rumen were also significantly decreased from 672 and 482 g/kg of DM (B100) to 475 and 43 g/kg of DM (BD100), respectively. By using Fourier transform infrared attenuated total reflection spectroscopy, we identified were significant changes in the spectral profiles of the CHO molecular structure in terms of lignin, STCHO, cellulosic compounds, and total CHO spectral peak area and height and their ratios. Pearson analysis results suggested strong correlations between lignin peak area, cellulosic compound area, and total CHO peak area and CHO nutrient profiles except energy values (net energy for lactation at 3 times maintenance intake, net energy for maintenance, and net energy for gain). No correlation was observed between STCHO peak area and CHO nutrient profiles in the mixture samples.
|
2022-09-28T17:47:08.233Z
|
219,701,657 |
{
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"DOI": "10.1111/ijlh.13200",
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},
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"url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/ijlh.13200"
}
|
Anemia is a major health burden worldwide and affects approximately one‐third of world's population. It is not a diagnosis; it is a manifestation of an underlying pathophysiology leading to either decreased hemoglobin (Hb), hematocrit (Hct), or red blood cells (RBCs). Iron deficiency anemia is still the most common cause of anemia worldwide. The symptoms are usually due to the underlying compensatory responses to decrease in oxygen delivery to the tissues. Laboratory investigation should start with complete blood count (CBC), reticulocyte count (RC), and peripheral smear evaluation. Further testing depends on these indices, that is, iron parameters and hemoglobinopathies/thalassemia evaluation in microcytic hypochromic anemia, vitamin B12, and folic acid level in macrocytic anemia. Increased RC denotes adequate bone marrow response and points toward hemolytic process and vice versa. Anemia diagnosis can be complex and confusing for the practicing physician. This review tries to give a practical simplistic approach to the diagnosis, focusing mainly on the basic parameters, that is, CBC, RC, and peripheral smear etc. Moreover, we have also tried to provide an update on the pyruvate kinase deficiency, as there has been recent exciting development in the management of these patients.
|
2022-10-14T00:45:28.288Z
|
32,562,909 |
{
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"ArXiv": null,
"DOI": "10.15255/CABEQ.2014.2130",
"MAG": "2481482903",
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|
An endo-β-1,4-glucanase (EG), produced under submerged fermentation by local isolate Trichoderma atroviride, was purified using ammonium sulfate precipitation, column and ion exchange chromatography with 55.16 fold and a specific activity of 30.9 EU mg –1 . The studies of PAGE, SDS-PAGE and zymogram test have been carried out. The EG had optimum activity at pH 5.0 and 50 °C respectively. Using CMC as substrate, the enzyme showed maximum activity (V max ) of 6.7 (µmol glucose min –1 ) mL –1 with its corresponding K m (Michaelis-Menten constant) value of 1.12 mg mL –1 . While the EG activity was activated by NaCl, inhibited by MgCl 2 and MgSO 4 . Otherwise, Tween 80, Triton X-100 and the total saponins known as biosurfactants enhanced the EG activity. The obtained EG had low K m and high thermal stability. Additionally, usability of the EG in biotechnological application was investigated. The results showed that the EG had potentially sufficient effects on denim fabric and pretreated lignocellulosic wastes.
|
2022-11-18T09:39:30.796Z
|
21,711,941 |
{
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"ArXiv": null,
"DOI": "10.1109/LSP.2018.2815692",
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|
This letter establishes a methodology to design threshold profiles for wideband ranging systems. Differently from conventional methods using a single threshold value that is designed based on the signal detection and false-alarm probability requirements, we propose a threshold profile that is designed based also on the ranging error requirement. The proposed method relies only on channel statistics without requiring channel estimation. A case study shows that, compared to conventional methods, the proposed method for threshold profiling significantly improves the performance in terms of false-alarm probability, detection probability, and ranging error.
|
2022-11-18T18:24:54.211Z
|
25,887,748 |
{
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"ArXiv": null,
"DOI": "10.1080/17470218.2015.1038571",
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"license": null,
"status": "GREEN",
"url": "https://www.pure.ed.ac.uk/ws/files/19403905/Rhodes_Parra_Logie_revision_2_final.pdf"
}
|
A large body of research has clearly demonstrated that healthy ageing is accompanied by an associative memory deficit. Older adults exhibit disproportionately poor performance on memory tasks requiring the retention of associations between items (e.g., pairs of unrelated words). In contrast to this robust deficit, older adults’ ability to form and temporarily hold bound representations of an object's surface features, such as colour and shape, appears to be relatively well preserved. However, the findings of one set of experiments suggest that older adults may struggle to form temporary bound representations in visual working memory when given more time to study objects. However, these findings were based on between-participant comparisons across experimental paradigms. The present study directly assesses the role of presentation time in the ability of younger and older adults to bind shape and colour in visual working memory using a within-participant design. We report new evidence that giving older adults longer to study memory objects does not differentially affect their immediate memory for feature combinations relative to individual features. This is in line with a growing body of research suggesting that there is no age-related impairment in immediate memory for colour-shape binding.
|
2022-11-21T18:11:49.697Z
|
19,210,992 |
{
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"DOI": "10.1107/S1600536810040912",
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"PubMedCentral": "3009065"
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"status": null,
"url": null
}
|
In the title compound, trans-[PdCl2{P(4-MeOC6H4)3}2]·C7H8, the Pd(II) atom lies on a center of symmetry, resulting in a distorted trans-square planar geometry. The Pd—P and Pd—Cl bond lengths are 2.3409 (4) and 2.2981 (4) Å, respectively. An intramolecular C—H⋯Cl hydrogen bond occurs. In the crystal, weak C—H⋯O interactions are observed between the aromatic rings of adjacent molecules. The toluene solvate molecule is equally disordered over two sets of sites.
|
2022-12-18T23:45:05.641Z
|
33,069,783 |
{
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"ArXiv": null,
"DOI": "10.1039/c3cc38474h",
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"license": null,
"status": "GREEN",
"url": "https://research-repository.griffith.edu.au/bitstream/10072/53483/1/88092_1.pdf"
}
|
A novel porous aromatic framework based on tetra-(4-anilyl)-methane and cyanuric chloride has been designed and synthesized successfully, which possesses permanent porosity and high selectivity of CO2 towards CH4.
|
2022-12-19T06:46:41.565Z
|
100,510,634 |
{
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"DOI": "10.1021/ACS.MACROMOL.6B02310",
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|
It will be shown that when polyether-b-amide (PEBA) is added to a PLA/PA11 blend, it tends toward the interface and results in a significant increase in the impact strength when all three phases are fully percolated. The addition of the elastomeric PEBA phase to the binary PLA/PA11 blend replaces a rigid PLA/PA11 interface with a much more deformable one. The further addition of PEO to PLA results in an ultratough material with an impact strength of ∼750 J/m, which is approximately 40 times greater than the original co-continuous PLA/PA11 blend. The tensile toughness and notched Izod impact strength are significantly influenced by the critical co-continuous composition region of the PLA/PA11 binary system and a minimum concentration to form a fully percolated PEBA layer at the co-continuous PLA/PA11 interface. The added PEO is also found to enhance the interfacial interactions and the chain mobility of PLA. The combined effects of co-continuity, strong interfacial interactions, a deformable interface, and...
|
2022-12-19T19:44:59.916Z
|
115,162,305 |
{
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"ArXiv": null,
"DOI": "10.18154/RWTH-2018-224474",
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|
This paper focuses on the faulty issues of the independent metering valve (IMV) in mobile applications. First, typical faults are studied in a 2t excavator to analyze their negative influences. The model of the abnormal system is estimated according to the results of fault detection and diagnosis. Accordingly, a fault-tolerance controller is designed to reconfigure normal controller by the coordinate control of other parallel available valves. With the presented fault operation, the dynamic characteristic under reconfigured modes can strictly match with that of faulty system. Simulations are conducted in the excavator to verify the fault-tolerance controller.
|
2022-09-04T06:24:26.950Z
|
209,657,739 |
{
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"DOI": "10.6342/NTU.2009.01933",
"MAG": "2254322498",
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|
1,4-Dichlorobenzene (1,4-DCB) is widely used as a deodorizer because of it’s volatility (vapor pressure is 1.08 mg/m3 at 25℃). It is also used as a moth repellent and toilet deodorizer. Many studies have showed that human exposed to 1,4-DCB mainly by inhalation. Human inhale high 1,4-DCB concentration may cause eye and upper respiratory tract irritation, abnormal liver/kidney function and lung disorders. In this study, we conduct an exposure assessment to clarify the relationship between 1,4-DCB exposure profile and the related health effects. The human internal dose can be analyzed by the concentrations of 1,4-DCB, 2,5-dichlorophenol (2,5-DCP), 2,5-dichlorophenol glucuronide (2,5-DCPG), and 2,5-dichlorophenol sulphate (2,5-DCPS) in urine. However, chemical standards of 2,5-DCPG and 2,5-DCPS are not commercially available, therefore, 2,5-DCPG and 2,5-DCPS were synthesized in our study. In the present study, we developed a method to analyze urinary 2,5-dichlorophenol (2,5-DCP), 2,5-dichlorohydroquinone, 2,5-DCPS, and 2,5-DCPG simultaneously by ultra-performance liquid chromatography coupled with tandem mass spectrometry (UPLC/MS/MS). Our method has been successfully used to detect urinary metabolites of 1,4-DCB with high throughput and represented a good sensitivity. After analysis method was established, we conducted an assessment of human 1,4-DCB exposure in three major moth repellent product plants, plant A and C are in northern Taiwan as well as plant B is in southern Taiwan. Plant C has the highest output of 1,4-DCB repellent product, and plant B has the smallest one. In our evaluated plants, samples of workers’ personal air and urine were simultaneously collected; in addition, we also collected workers’ questionnaire and biochemical test results. Our data has demonstrated the concentration of free form 2,5-DCP/2,5-DCPS in urine was generally lower (70 ~ 1050 ng/mL) than 2,5-DCPG (20 ~ 350 mg/L). Therefore, 2,5-DCPG was found to be the major metabolite after human exposed to 1,4-DCB. For air sampling, we used 3M 3500 passive sampler to evaluate repellent workers’ exposure profile. The sampling time included 8 hours daytime, and 16 hours overnight. After sampling, the air samples were analyzed by Gas Chromatography Flame Ionization Detector (GC-FID). Our results demonstrated that the highest air concentration (9.15 ± 6.37 ppm in daytime and 0.84 ± 0.68 ppm in over night) wad found in plant C, and plant B had the lowest concentration (1.19 ± 0.84 ppm in daytime and 0.08 ± 0.04 ppm in over night ). From the statistical results, the 1,4-DCB concentration in air was significantly higher in on-site workers than in non-on-site workers (p < 0.05). Moreover, the air concentration was also found to be higher in raw material operator than in semi-finished product collector (p < 0.05). The air concentration was higher in who has the habit of using mothball contained 1,4-DCB in home (p < 0.05). Once the worker has the higher air concentration of 1,4-DCB, their metabolite concentration in urine was also found to be higher (p < 0.05). In health effect, the biochemical indices such as white blood cell count (WBC), blood urea nitrogen (BUN) level and BUN/creatinine ratio are positively correlated with the air concentration and urinary metabolite concentration (p < 0.05). This study employed solid-phase extraction (SPE) to extract 1,4-DCB metabolites from urine and the metabolites were then subsequent to analysis by UPLC/MS/MS coupled with negative electrospray ionization. This method has successfully measured urinary metabolites of 1,4-DCB with high throughput and represented a good sensitivity. We found the major metabolite of 2,5-DCP in urine is 2,5-DCPG. From air sampling results, the 24 hours sampling data is much closer to the real exposure situation than 8 hours sampling. The concentration of 1,4-DCB in air and major metabolite in urine are positively correlated with WBC count, BUN concentration and BUN/creatinine ratio, but these indices is still in the normal range.
|
2022-01-27T06:52:15.609Z
|
233,783,913 |
{
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"DOI": "10.1158/1557-3265.ADI21-IA-22",
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}
|
The delivery of radiation for the treatment of cancer is a complicated process that requires both clinical and technical expertise to ensure radiation treatments are safe and effective. Sub-optimal radiation treatments have the potential to result in significant detriment to the patient and several studies have shown radiation treatments, which deviate from established clinical guidelines, result in worse patient outcomes. Therefore, the current radiation treatment process requires substantial multi-disciplinary resources to both generate and verify radiation treatments are of high-quality. In this talk, a previously validated machine learning platform customized for radiation oncology will be presented. The method automatically learns based on data from thousands of previously treated patients which relationships and patterns in radiation oncology image and treatment data and has been applied for automated data mining activities, automated quality assurance to support expedited radiation treatment review, and for radiation dose prediction to develop new radiation treatments by best deciding where dose should be placed and how dose should be delivered without requiring any manual intervention. Therefore, the method can be used to both generate personalized radiation treatments and to quantitatively score radiation treatments for quality and classify radiation treatments that have errors. The automated platform can readily be integrated into current clinical process to improve efficiency in the radiation treatment planning and plan review processes and to better utilize the vast data we have to ensure we are providing patients with highly personalized radiation treatments. Citation Format: Thomas G. Purdie. Automated treatment planning and quality assurance in radiation oncology [abstract]. In: Proceedings of the AACR Virtual Special Conference on Artificial Intelligence, Diagnosis, and Imaging; 2021 Jan 13-14. Philadelphia (PA): AACR; Clin Cancer Res 2021;27(5_Suppl):Abstract nr IA-22.
|
2022-02-07T21:45:30.828Z
|
92,008,127 |
{
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"DOI": "10.32007/med.1936/jfacmedbagdad.v59i4.8",
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"license": "CCBYNC",
"status": "GOLD",
"url": "http://iqjmc.uobaghdad.edu.iq/index.php/19JFacMedBaghdad36/article/download/71/49"
}
|
خلفية الموضوع: العلاقة بين التغير الوراثي رقم 308 لعامل تنخر الخلايا السرطانية نوع الفا ومرض السكري النوع الثاني يبقى مصدر جدل واختلاف في الاصول وانماط الحياة التي تلعب دور مهم في هذا التضارب.
الهدف :لبحث دور التغير الوراثي رقم 308 في عامل تنخر الخلايا السرطانية نوع الفا مع مرض السكري النوع الثاني ومعيار كتلة الجسم في هؤلاء المرضى.
طرائق العمل: الدراسة الحالية تضمنت خمسون مريض مصاب بداء السكري النوع الثاني بالإضافة الى خمسة وعشرون شخص كمجموعة ضابطة. معدل العمر كان 43.54سنة بينما للأصحاء كان 45.04سنة. تم قياس مستوى السكر بعد الصيام وكذلك الكولسترول والدهون الثلاثية بواسطة الطرق الكيميائية .معيار كتلة الجسم قد عمل لكلا المرضى والاصحاء. تم تحديد مستوى عامل تنخر الخلايا السرطانية نوع الفا في مصل مرضى السكري النوع الثاني وكذلك الاصحاء بواسطة الطرق الانزيمية المناعية. تم تحديد التغير الوراثي لعامل تنخر الخلايا السرطانية رقم 308 بواسطة الهضم بالإنزيمات القاطعة بعد البلمرة .
النتائج: مرضى السكري النوع الثاني الذين يحملون النوع الوراثي Aلعامل تنخر الخلايا السرطانية نوع الفا قد اظهروا علاقة وثيقة مع معيار كتلة الجسم ومستوى عامل تنخر الخلايا السرطانية نوع الفا والمعدل هو (76.98±89.06)(3.41±28.75) بالتتابع. عندما نقارن هذا مع النوع الوراثي نوع Gكذلك اظهر علاقة وثيقة مع معيار كتلة الجسم ومستوى عامل تنخر الخلايا نوع الفا (2.88±22.57)(2.987±8.269) بالتتابع ’بصورة عامة النوع الوراثي الهجين GAلعامل تنخر الخلايا السرطانية نوع الفا وضح علاقة وثيقة مع معيار كتلة الجسم ومستوى عامل تنخر الخلايا نوع الفا اوضح علاقة قوية مع معيار كتلة الجسم ومستوى عامل تنخر الخلايا السرطانية نوع الفا (3.05±27.25)(26.699±48.37)عندما يقارن مع النوع السائد GG .
اظهر مستوى السكر في الدم بعد الصيام علاقة قوية مع التغير الوراثي رقم 308 لعامل تنخر الخلايا السرطانية مع معدل الانواع الوراثية AA ;GA(225±62.902)(216.75±29.97) حسب الترتيب ,عندما يقارن مع النوع الوراثي السائد GG(203.46±31.89).مستوى عامل تنخر الخلايا السرطانية لم يعطي علاقة واضحة مع معيار كتلة الجسم لمرضى السكري النوع الثاني.
الاستنتاجات : في هذه الدراسة التغير الوراثي لعامل تنخر الخلايا السرطانية ((AA,GA اظهر علاقة وثيقة جدا مع مستوى عامل تنخر الخلايا السرطانية في مصل مرضى السكري النوع الثاني وكذلك مع معيار كتلة الجسم .الانواع الوراثية لعامل تنخر الخلايا السرطانية AA,GA أوضحت علاقة وثيقة مع مستوى السكر بعد الصيام.
|
2022-02-10T18:14:07.136Z
|
161,923,362 |
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"DOI": "10.7202/018684AR",
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|
Cet article se propose d’analyser la lutte menee par un reseau transnational d’activistes pour la reconnaissance et le respect des droits des homosexuels masculins en Asie centrale postsovietique. Apres avoir souligne l’action de ce reseau, nous nous attacherons a montrer ce a quoi ses membres se trouvent confrontes, soit le poids des realites locales dans lesquelles se debattent leurs partenaires centrasiatiques, les goluboi ou « bleu », comme se nomment eux-memes les homosexuels masculins d’Asie centrale. Cette analyse chronologique, remontant au debut du siecle, permettra non seulement de comprendre les decalages entre les attentes des militants europeens et nord-americains et les partenaires locaux du reseau, mais aussi de montrer la force d’un tel reseau transnational dans une region caracterisee par un fort controle de l’Etat sur la vie politique. Nous nous appuierons sur les donnees disponibles, mais surtout sur les recherches de terrain que nous menons dans la region depuis 1995. Car si les etudes sur la sexualite en Asie centrale post-sovietique sont peu nombreuses, celles portant sur l’homosexualite masculine sont quasiment inexistantes dans la litterature scientifique internationale.
|
2022-03-25T00:43:53.530Z
|
144,090,247 |
{
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"ArXiv": null,
"DOI": "10.1017/S0140525X07000878",
"MAG": "1999934373",
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"status": null,
"url": null
}
|
The beliefs, preferences, and constraints framework provides a language that economists, and possibly others, may largely share. However, it has got so many levels of indeterminacy that it is otherwise almost meaningless: when no evidence can ever be a problem for scientific construct Z, then there is a problem for Z, for nothing can also be considered supportive of Z.
|
2022-02-09T07:08:58.779Z
|
241,060,814 |
{
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"DOI": "10.26226/morressier.5d1a037457558b317a1404f1",
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"PubMedCentral": "9129383"
},
"license": "CCBYNCND",
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"url": "https://openresearchlibrary.org/ext/api/media/fab58fd1-71ed-480a-bede-f8af6aa0365d/assets/external_content.pdf"
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|
Objectives Although yoga has efficacy in treating depression, no studies have examined the relative clinical benefits of different modalities of administering yoga (group v/s individual). This has potential impact on the scaling-up of delivering yoga therapy. We aimed to assess the differential efficacy of individual v/s group yoga as an add-on treatment in unipolar depression. Methods Thirty-four patients with unipolar depression were randomized to receive 12 sessions of individual (n=18) or group (n=16) yoga. Differential efficacy (HAM-D, HAM-A, CGI-S, N-Back-1 & 2), yoga performance (YPAS) and attrition rates between the two treatment conditions were examined using non-parametric tests. Results Attrition rates of 33.33% (n=6) and 62.5% (n=10) were found in individual and group yoga respectively (p>0.05). Post intervention, statistically significant improvement in HAM-D, N-Back-2 Hits and Errors were found in both individual (n=12; p<0.05) and group (n=6; p<0.05) yoga. Additionally, significant improvement in HAM-A, CGI-S and N-Back-1 Hits (n=12; p<0.05) was found only in individual, but not in group (n=6; p>0.05) yoga. However, there was no significant interaction effect for any of the outcomes, indicating the magnitude of improvement in individual and group yoga were not significantly different (p<0.05). Yoga performance did not show statistically significant difference (p>0.05) between individual and group sessions. Conclusion We demonstrate that group and individual yoga are equally effective for depression. These observations support the utility of larger dissemination of yoga therapy for depression through group sessions. The findings, however, should be cautiously interpreted due to limited sample size. Running Title: Yoga intervention in unipolar depression
|
2022-06-14T11:48:42.087Z
|
152,004,466 |
{
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"DOI": "10.29173/MD28628",
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}
|
This paper analyzes the staging of domestic space and gender reversals in Jose Triana's La noche de los asesinos and Ariel Dorfman's La muerte y la doncella . Both aspects indicate the intersection between space and identity, especially in regards to the enforcement of patriarchal order. Although differing in their political contexts, both plays explore the oppression and containment of fixed gender and spatial values under authoritarian regimes and how such repression leads to a reversal of gender identities and the emergence of liminal spaces.
|
2022-06-04T05:31:53.718Z
|
213,436,293 |
{
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"DOI": "10.14341/osteo10286",
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"license": "CCBYNCND",
"status": "GOLD",
"url": "https://www.osteo-endojournals.ru/jour/article/download/10286/9240"
}
|
Bisphosphonates is a first-line therapy for treatment of osteoporosis. In the last decade, the number of atypical femur fracture (AFF) cases during long-term treatment with bisphosphonates has increased. The aim of this article was to analyze the literature data on this problem, to define the diagnostic criteria of AFF and to present the case of AFF in the patient who received treatment with alendronate for 3.5 years. A 78-year-old woman, receiving oral bisphosphonate for severe postmenopausal osteoporosis for 3.5 years, suddenly started feeling pain in her right thigh while walking. Three months later, she had got a fracture in middle third of the right femur after falling from her standing height. According to instrumental diagnostics, this fracture had all criteria of AFF. Blocking intramedullary osteosynthesis with shafts was performed. A retrospective analysis of soft tissue magnetic resonance imaging in the area of right thigh, done before the fracture, showed the presence of undiagnosed incomplete right femur fracture in the middle third, which subsequently led to a complete fracture. Presented clinical case demonstrates the complexity of AFF diagnostics. The purpose of the publication is to draw attention of medical specialists to the issue of this rare side effect of bisphosphonate treatment.
|
2022-05-01T17:18:14.429Z
|
21,679,399 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/SMARTTECHCON.2017.8358613",
"MAG": "2801401907",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A green Library is designed to minimize negative impact on the natural environment and maximize in door environmental quality by means of careful site selection, use of natural construction materials and biodegradable products conservation of resources (Water, energy, paper) and responsible waste proposal (recycling etc). Green Library is a part of Green building movement. There are several reasons why library would want to build green or incorporate green features into their buildings by using Smart Technology. First, the cost of constructing green buildings has become affordable. Second, most reading available energy resources to finite resources. Smart Technology means basically monitors and analysis of the hard drives which helps the workplace to save money and Energy. In this article., how by using smart Technology in Green Libraries reduce energy consumption, smart technology revolution to the development of Green Buildings by using mobile tools for accessing digital information and modernizing Library Missions.
|
2022-07-29T05:25:44.530Z
|
25,836,076 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/TNS.2006.880940",
"MAG": "2137614027",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Increasing complexity of safety-critical systems that support real-time multitasking applications requests the concurrency management offered by real-time operating systems (RTOS). Real-time systems can suffer severe consequences if the functional as well as the time specifications are not met. In addition, real-time systems are subject to transient errors originating from several sources, including the impact of high energy particles on sensitive areas of integrated circuits. Therefore, the evaluation of the sensitivity of RTOS to transient faults is a major issue. This paper explores sensitivity of RTOS kernels in safety-critical systems. We characterize and analyze the consequences of transient faults on key components of the kernel of MicroC, a popular RTOS. We specifically focus on its task scheduling and context switching modules. Classes of fault syndromes specific to safety-critical real-time systems are identified. Results reported in this paper demonstrate that 34% of faults that affect the scheduling and context switching functions led to scheduling dysfunctions. This represents an important fraction of faults that cannot be ignored during the design phase of safety-critical applications running under an RTOS
|
2022-09-08T06:23:37.193Z
|
110,927,061 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/PCCON.1997.638314",
"MAG": "2164110100",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper describes the operation of a three-phase PWM power converter under disturbances caused by inevitable power faults. The output voltage ripple from input power unbalances-especially caused by a single line-to-ground fault (SLGF)-is analyzed to represent the amplitude of the ripple with some given parameters. This paper also shows that some converters' operation can be unstable when using a synchronous frame controller by unbalanced input power resulted from a SLGF. The authors discuss a method that makes the power converter run within a certain voltage ripple boundary even under faulted power conditions. Finally, the operation of the discussed power converter is simulated and experimented upon in order to verify the results.
|
2022-09-10T09:24:22.468Z
|
247,363,415 |
{
"externalids": {
"ACL": null,
"ArXiv": "2207.09452",
"DOI": "10.1017/S0004972721001301",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Here, it is interesting to note that while a lot of effort was put into making Vinogradov’s proof of Goldbach’s weak conjecture completely explicit, not much work was put into making Chen’s theorem explicit, while arguably this result is an even better approximation of Goldbach’s conjecture. The only attempt was made by Yamada [14], but some mistakes can be found in the proof. (See [14, (87) and (104)], where a log term appears to be missing. Also, no proof is given of the explicit version of the linear sieve that is used and this version is inconsistent with the versions in [11, 12]). We also show that the following result follows readily from Theorem 1.
|
2022-11-17T11:29:42.924Z
|
16,600,369 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5220/0004516500980110",
"MAG": "1518843016",
"PubMedCentral": null
},
"license": "pd",
"status": "GREEN",
"url": "http://www.infosec.aueb.gr/Publications/SECRYPT-2013%20Panopticon%20vs%20Privacy.pdf"
}
|
Social media and Web 2.0 have enabled internet users to contribute online content, which may be crawled and utilized for a variety of reasons, from personalized advertising to behaviour prediction/profiling. One negative case scenario is the political affiliation profiling. Our hypothesis is that this scenario is nowadays realistic, applicable to social media, and violates civil rights, privacy and freedom. To demonstrate this, we developed a horror story, i.e., a Panopticon method, in order to reveal this threat and contribute in raising the social awareness over it. The Panopticon relies on data/opinion mining techniques; hence it classifies comments, videos and playlists, collected from the popular social medium YouTube. Afterwards, it aggregates these classifications in order to decide over the users' political affiliation. The experimental test case of the Panopticon is an extensive Greek community of YouTube users. In order to demonstrate our case, we performed an extensive graph theoretical and content analysis of the collected dataset and show how and what kind of personal data (e.g. political attitude) can be derived via data mining on publicly available YouTube data. Then, we provide the reader with an analysis of the legal means that are available today, to a citizen or a society as a whole, so as to effectively be prevented from such a threat.
|
2022-12-17T05:19:49.178Z
|
14,611,891 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2139/ssrn.2314822",
"MAG": "86949293",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://econpapers.repec.org/scripts/redir.pf?u=https%3A%2F%2Fdocs.iza.org%2Fdp7527.pdf;h=repec:iza:izadps:dp7527"
}
|
We follow Brodaty et al. (2008) and develop a model within the signalling literature where an employer decides whether to hire a worker or not conditionally on the signals she sends – field and length of study and high education (HE) institution. The empirical design of our paper builds on evidence relative to first labour market entry of graduates to identify a signalling effect of individual and institutional quality of study on individual horizontal match quality. First, based on a matched unique employer-employee dataset we report the extent of horizontal mismatch for graduates of different fields of education for a post-transition economy (Slovenia). Second, we test the signal of HE institutions and above average study duration on the likelihood of a horizontal mismatch separately for each field of education. We find that graduates from specific HE institutions experience significantly higher likelihood to get a job that matches the field of study for social sciences, namely business and administration and to a smaller extent education. On the contrary, HE institutions do not signal skills or abilities in the most technical fields of education (engineering, computing, manufacturing). The above average study duration has mixed effects based on the field of education. It can either signal lower innate ability (i.e. for law graduates) or increased skills due to student work (i.e. computing graduates).
|
2022-12-18T09:26:04.823Z
|
29,567,857 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1055/S-2007-979626",
"MAG": "2054210767",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Acute ethanol consumption by fasting male volunteers decreases circulating trytophan (Trp) concentration and availability to the brain as determined by the ratio of (Trp) to the sum of its five competitors ([Trp]/[CAA]ratio). These effects of alcohol are specific to Trp, because levels of the 5 competitors are not increased. The decrease in circulating (Trp) is not associated with altered binding to albumin and may therefore be due to enhancement of hepatic Trp pyrrolase activity. It is suggested that, under these conditions brain serotonin synthesis is likely to be impaired and that, as a consequence, a possible strong depletion of brain serotonin in susceptible individuals may induce aggressive behaviour after alcohol consumption. The possible implications of these findings in the relationship between alcohol and depression are also briefly discussed.
|
2022-12-20T00:49:32.863Z
|
244,971,841 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.34007/WARISAN.V2I1.680",
"MAG": "3183246445",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This article discusses the Magido Bantu tradition practiced by the Mandailing ethnic group in Jorong Tamiang Ampalu, West Pasaman Regency. This tradition has become a custom that is commonly practiced before a horja (wedding ceremony) is held. This study uses the historical method in four writing steps, namely; heuristics, verification or criticism, interpretation, and historiography, with a cultural approach. The Padri war that occurred to the Mandailing land area led to the migration of the Mandailing ethnic group who had embraced Islam to the Minangkabau region. This migration also brings with it customs and traditions that were previously practiced, one of which is the Magido Bantu tradition. This tradition has its own procession and implementation procedures that are different from the traditions commonly practiced by the Mandailing ethnic group in other regions. The implementation of this tradition has so many positive values in it, including: an attitude of help, mutual respect, deliberation, and so on. This tradition is still being maintained until now, if a horja is not held it will feel less than perfect.
|
2022-08-14T18:23:34.549Z
|
33,546,084 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2139/ssrn.1676010",
"MAG": "2163740415",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "http://www.ifn.se/wfiles/wp/wp822.pdf"
}
|
I construct a model of public policy development, and use the model to explain why the United States has a comparatively small public sector, but instead a large "private welfare state" with employment-based benefits. The key factors are politically organized firms and labor unions. These interest groups can use campaign support to influence a political decision-maker who decides whether to implement a social benefit. In addition, the firms can influence the outcome indirectly by privately providing their own workers with the benefit. This setup leads to three possible outcomes. In the first, no one is provided the social benefit. In the second, all workers receive it through government provision. In the third, some workers receive the policy, through their employers. I argue that the features leading to the third equilibrium correspond closely to political institutions and industry characteristics of the US, while the features of the second equilibrium better describe European countries.
|
2022-08-25T02:38:18.871Z
|
237,888,303 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.20944/preprints202106.0602.v1",
"MAG": "3195963516",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GREEN",
"url": "https://www.mdpi.com/2227-9717/9/8/1462/pdf?version=1629557729"
}
|
Nowadays, some coffee production centers are still classification manually, so it requires a very long time, a lot of labor, and expensive operational costs. Therefore, the purpose of this research was to design and performance of the coffee bean classifier that can accelerate the process of classification beans. The classifier used consists of three main parts, namely the frame, driving force, and sieves. Research parameters include classifier work capacity, power, specific energy, classification distribution and effectiveness, and efficiency. The results showed that the best operating conditions of the coffee bean classifier was found at a rotational speed of 91.07 rpm and a 16° sieves angle with a classifier working capacity of 38.27 kg/h, the distribution of the seeds retained in the first sieve was 56.77 %, the second sieves was 28.12%, and the third sieves was 15.11%. The efficiency of using a classifier was found at a rotating speed of 91.07 rpm and a sieves angle of 16°. This classifier was simple in design, easy to operate, and can sort coffee beans into three classification, namely small, medium, and large.
|
2022-12-10T09:19:23.185Z
|
56,101,928 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.7307/PTT.V29I4.2338",
"MAG": "2753280880",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
There are several possible bus stop locations and configurations. A bus stop can be located before or after the intersection as curb-side stop, bus bay or bus bulb. Determining the proper configuration and location of bus stop represents an important planning decision. While previous research efforts in literature have suggested some advantages and disadvantages regarding bus stop locations and configurations, little effort has been made towards understanding the joint impact of bus stop location and configuration on the transit and other vehicle traffic performance on the intersection. So, this paper analyses the joint impact of bus stop location and configuration on the operational characteristics of traffic flow in terms of average bus trip time and control delay. These operational performance measures for various intersection layouts, volume distributions, movement splits, average bus dwell times and bus departure frequencies have been obtained using calibrated microsimulation traffic software.
|
2022-09-11T07:17:16.706Z
|
253,949,546 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1079/cabicompendium.29271",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This datasheet on Julbernardia globiflora covers Identity, Distribution.
|
2022-11-26T18:31:29.482Z
|
46,080,771 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/APMC.2008.4958081",
"MAG": "2112976661",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
An artificial surface with asymmetric reflection properties is presented. By covering a metal ground plane with periodic metal-dielectric composite textures, the electromagnetic reflection properties can be altered. By tuning the individual lattice of a periodic mushroom-type texture to vary the surface impedance, a surface with graded reflection phases as a function of position can be designed. Applying a linear gradient in the reflection coefficient phase along the face, the proposed surface is electromagnetically inclined, even though physically flat. For the whole ranges of the incident angle, this metasurface reveals asymmetric reflection properties contrary to the law of reflection. The reflection patterns from the surface, the boundary condition, and the relation between the incident angle and the reflection angle are presented.
|
2022-12-16T03:16:41.968Z
|
12,311,217 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1469-8749.1994.tb11918.x",
"MAG": "1969501335",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
I X J K I N G fetal life, the placenta and maternal circulation supply everything the fetus requires for growth and development. I f the infant is born pretcrm, i t is prematurely separated from this source of sustenance. In addition to being deprived of placental-maternal respiratory and nutritive functions, the prcterm infant is also deprived of placental-maternal endocrine function. Besides being the conduit for delivery of maternal hormones to the fetus, the placenta produces prodigious amounts of steroid and protein hormones, neuropeptides and growth factors, some of which are found in much higher concentrations in fetal than in maternal blood. The placental anatomic arrangement is reminiscent of the hypothalamicpituitary system and has prompted consideration that it performs that function until fetal hypothalamicpituitary maturation has been achieved’. With respect to some hormones, premature loss of the placenta may be analogous to partial pituitary stalk section. The consequences of the premature loss of placental endocrine function are poorly understood. In this annotation, we offer the hypothesis that some of the developmental problems experienced by preterm newborn infants reflect a deprivation of placenta-provided hormones and growth factors during crucial stages of neurodevelopment. We present evidence to support the specific hypothesis that transient hypothyroxinernia of prematurity results from birth-induced deficiency of placental thyrotropin releasing hormone (TRH), and represents a clinically significant episode of hypothyroidism that may result in impaired neurodevelopment in later childhood.
|
2022-12-19T08:32:06.729Z
|
234,669,626 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21203/rs.3.rs-78133/v1",
"MAG": "3114647093",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GREEN",
"url": "https://www.researchsquare.com/article/rs-78133/latest.pdf"
}
|
Background: By the end of August 2020, >23 million cases and 800,000 deaths were attributed to SARS-CoV-2 in >200 countries. The improvement of simple, rapid, and efficient detection methods is of great significance for the early detection, timely isolation, and protection of susceptible populations. This study aimed to provide an alternative method for the rapid detection of viral nucleic acid.Methods: This study provided a rapid nucleic acid detection method mediated by recombinant enzyme based on the novel coronavirus (SARS-CoV-2). Primers and probes were designed based on the N gene sequence of coronavirus. The method was performed at 39 °C, the detection time was short (<20 min), and the detection limit was up to 101 copies/mL.Results: The primer-probe did not show any cross-reaction with adenovirus, Zika virus, influenza B virus, and chikungunya virus, with good specificity. A total of 106 clinical throat swab samples were compared by reverse transcription recombinase-aided amplification (RT-RAA) and commercial reverse transcription-quantitative real-time polymerase chain reaction (RT-qPCR); the results were identical.Conclusions: The novel coronavirus RT-RAA method established in this study had high sensitivity, strong specificity, simple operation, and fast detection speed, and hence, is suitable for the rapid detection of novel coronavirus under the current epidemic situation.
|
2022-12-21T00:26:44.800Z
|
254,781,168 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/ofid/ofac492.579",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Sepsis is a common and costly condition encountered in United States hospitals and Emergency Departments (ED). Studies have shown that the incidence of sepsis and risk of sepsis morbidity and mortality increases with age. With increased efforts on early detection and process of care, in-hospital sepsis deaths have declined; however, racial disparities have been observed in sepsis-related outcomes. The objective of this study was to assess demographic, severity, and outcome differences among septic patients presenting to the ED self-reporting as White vs. Black, and evaluate the potential of an investigational cellular host response test in risk stratifying these subpopulations for risk of poor outcomes.
The IntelliSep test is an investigational in-vitro diagnostic that quantifies the state of immune activation by measuring the biophysical properties of leukocytes from a routine whole blood sample in under 10 minutes. The result is the IntelliSep Index (ISI), ranging between 0.1-10.0, stratified into three discrete interpretation bands of increasing disease severity risk: Green, Yellow, and Red.
Adult patients presenting to the ED with signs or suspicion of infection were prospectively enrolled in four discrete but similar cohorts at multiple sites in the USA (Feb. 2016 – Apr. 2020). All patients had ISI performed and were followed by retrospective chart review for outcome information and sepsis adjudication. Treating clinicians did not have access to assay results, and only those determined to be septic were included in the final analysis.
Of the 150 patients included in the analysis, 92 (61%) were White and 58 (39%) Black. No significant differences were observed in biological sex or severity of illness (Fig). Black subjects were significantly younger (mean difference 8.9 years; p < 0.001) compared to Whites. Independent of race, the ISI correlated with increasing likelihood of adverse sepsis-related outcomes.
Biological sex and APACHE II scores by ISI Interpretation Band for White and Black Study subjects.
The ISI is an objective tool for the quantification of immune activation, and adequately risk-stratifies patients with sepsis for adverse outcomes, independent of race. This finding suggests that social determinants of health, rather than differences in immunobiology, contribute to racial disparities observed in sepsis-related outcomes.
Roya Sheybani, PhD, Cytovale: Employee|Cytovale: Stocks/Bonds Henry T. Tse, PhD, Cytovale: Stocks/Bonds Ajay M. Shah, PhD, Cytovale Inc: Board Member|Cytovale Inc: Ownership Interest|Cytovale Inc: Stocks/Bonds.
|
2022-12-17T18:32:00.098Z
|
143,238,475 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1515/zfsoz-2000-0204",
"MAG": "1848972891",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "http://www.degruyter.com/downloadpdf/j/zfsoz.2000.29.issue-2/zfsoz-2000-0204/zfsoz-2000-0204.xml"
}
|
Zusammenfassung Ausgehend von dem zentralen Problem der unbeobachteten Heterogenität in der empirischen Sozialforschung wird zur Lösung des Problems das statistische Verfahren der finiten Mischung von Mittelwert- und Kovarianzstrukturmodellen vorgestellt. In diesem Modell kann der Erwartungswert jeder Komponente der Mischung sowohl von normalverteilten als auch von nicht normalverteilten Regressorvariablen abhängen. Der Erwartungswert und die Kovarianzmatrix jeder Komponente der Mischung werden als konditionale Mittelwert- und Kovarianzstrukturmodelle (z. B. vom Typ LISREL) parametrisiert. Zur Schätzung der Parameter werden drei Schätzstrategien vorgestellt, Teststatistiken für die geschätzten Parameter, Fit-Indices zur Modellprüfung sowie zwei Testverfahren auf die Anzahl der Komponenten werden angegeben. Modellspezifikation und Schätzverfahren werden in der Form von Mischungen konditionaler LISREL-Modelle zur Identifikation heterogener Personengruppen bezüglich der Lebenszufriedenheit an den Wohlfahrtssurvey 1993 angewendet. Als Ergebnis werden drei Typen identifiziert, die sowohl einen unterschiedlichen Grad an Lebenszufriedenheit als auch eine unterschiedliche Beziehungsstruktur zwischen den Zufriedenheiten in einzelnen Lebensbereichen, allgemeiner Lebenszufriedenheit und sozialstrukturellen Determinanten aufweisen.
|
2022-09-12T02:31:20.400Z
|
225,740,860 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.20527/klik.v7i2.320",
"MAG": "3037984451",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "http://klik.ulm.ac.id/index.php/klik/article/download/320/pdf"
}
|
Hand gestures are the communication ways for the deaf people and the other. Each hand gesture has a different meaning. In order to better communicate, we need an automatic translator who can recognize hand movements as a word or sentence in communicating with deaf people. This paper proposes a system to recognize hand gestures based on Indonesian Sign Language Standard. This system uses Myo Armband as hand gesture sensors. Myo Armband has 21 sensors to express the hand gesture data. Recognition process uses a Support Vector Machine (SVM) to classify the hand gesture based on the dataset of Indonesian Sign Language Standard. SVM yields the accuracy of 86.59% to recognize hand gestures as sign language. Keywords : Hand Gesture Recognition, Feature Extraction, Indonesian Sign Language, Myo Armband, Moment Invariant
|
2022-03-18T00:16:56.120Z
|
3,878,304 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/JSEN.2018.2806994",
"MAG": "2793619032",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Business models around energy performance of lighting systems and managed services make increasing use of the energy metering sensor data. However, accurate submetering solutions remain expensive and complex to commission. With the goal of realizing a low-cost metering sensor solution that provides reasonable measurement accuracy, we consider nonintrusive load monitoring for lighting systems using virtual energy submetering. We propose analytics methods using metered lighting energy sensor data to address three problems: 1) provide initial validation of assets of a lighting control system; 2) disaggregate energy consumption across distinct control groups of a validated system enabling usage and performance monitoring; and 3) monitor and manage lighting system asset over lifecycle. The proposed methods are evaluated using an experimental testbed in a commercial building.
|
2022-09-30T08:11:47.750Z
|
36,377,363 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1089/15258160151134962",
"MAG": "2008491027",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
On the horizon of modern molecular medicine is the requisite technology to capture multipotent human stem cells that are capable of self-renewal and to direct these stem cells along defined lineages for therapeutic purposes. In this article, we describe the hematopoietic and mesenchymal differentiation potential of a unique population of transforming growth factor-beta1 (TGF-beta1)-responsive stem cells derived from murine bone marrow. Stringent selection of the stem cells was accomplished under low serum conditions by virtue of an inherent survival response to a TGF-beta1-vWF fusion protein that was bound to collagen matrices. The TGF-beta1-responsive stem cells initially exhibited a non-adherent and uniformly blastoid morphology, underwent expansion into colonies upon serum reconstitution, and were capable of overt cytodifferentiation along fibrogenic, osteogenic, chondrogenic, or adipogenic lineages upon growth factor stimulation. Remarkably, these stem cells also underwent rapid expansion in the presence of either hematopoietic stem cell factor (SCF) or interleukin3 (IL-3), and differentiated into myeloid and lymphoid phenotypes upon exposure to the latter. Taken together, these results support the hypothesis that pluripotent premesenchymal prehematopoietic progenitor cells, designated P4 stem cells, are present postnatally in murine bone marrow and, thus, may be summarily isolated for various cell-based experimental therapies.
|
2022-12-19T04:45:02.960Z
|
193,121,001 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.32399/RDK.0.25.619",
"MAG": "2924674578",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
El presente articulo se ocupa del analisis del sistema de proteccion de la propiedad intelectual en China. En los 38 anos transcurridos desde su adhesion al Convenio de la ompi1 y a casi 17 de suscribir el adpic, 2 China ha experimentado avances notables en la construccion y fortalecimiento de su marco normativo de propiedad intelectual, a tal grado que la presentacion de solicitudes de patente, registros marcarios y disenos industriales en todo el mundo registro cifras record en 2016, observandose una fuerte demanda en China, recibiendo un numero de solicitudes de patente mayor que el total correspondiente a los Estados Unidos, Japon, Republica de Corea y la oep, 3 considerados en conjunto. Asimismo, se observo un marcado incremento del 16,4% en el numero de solicitudes de registro de marcas, que ascendio a unos 7 millones, y las solicitudes de registro de dibujos y modelos industriales en todo el mundo aumento del 10,4 % hasta alcanzar casi un millon –dichos aumentos impulsados tambien por el incremento observado en China-. A pesar de lo anterior, si bien China ha avanzado en la construccion de un sistema legal coherente para la proteccion de la propiedad intelectual, las estadisticas tambien la colocan como la mayor economia productora de mercancias falsificadas.
|
2022-01-23T04:17:36.854Z
|
19,209,177 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICTC.2012.6387171",
"MAG": "2028293471",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A novel type of compact and printed pattern reconfigurable antenna for dual Wireless LAN application is presented. Dual band is realized by dipole and bow-tie antenna which is connected by a chip inductor. Also, each parasitic element as a reflector changes the direction of main beam. Results show good pattern reconfigurablity for WLAN dual band.
|
2022-02-12T23:15:49.603Z
|
53,533,359 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3844/JMSSP.2018.7.15",
"MAG": "2780595133",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This article aims to identify the generating function of modified Apostol type q-Bernoulli polynomials. With the aid of this generating function, some properties of modified Apostol type q-Bernoulli polynomials are given. It is shown that aforementioned polynomials are q-Appell. Hence, we make use of these polynomials to have applications on q-Umbral calculus. From those applications, we derive some theorems in order to get Apostol type modified q-Bernoulli polynomials as a linear combination of some known polynomials which we stated in the paper.
|
2022-12-02T12:16:37.792Z
|
219,322,077 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4161/cbt.8.13.9312",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
--Whole-Genome Searches Are Revealing Secrets of a Childhood Cancer— Two new studies from The Children’s Hospital of Philadelphia advance the search for genetic events that result in neuroblastoma, a puzzling, often-deadly type of childhood cancer. Originating in the peripheral nervous system, neuroblastoma is the most common solid cancer of early childhood and causes 15 percent of all childhood cancer deaths. “Only two years ago we had very little idea of what causes neuroblastoma,” said study leader John M. Maris, M.D., chief of Oncology and director of the Cancer Center at The Children’s Hospital of Philadelphia. “Now we have unlocked a lot of the mystery of why neuroblastoma arises in some children and not in others.” In the largest gene study to date in pediatric oncology, Maris’s study team performed a genome-wide association study to discover that common variants in the gene BARD1 increase a child’s susceptibility to a high-risk form of neuroblastoma. A second genome-wide study found that a copy number variation (CNV)—a missing stretch of DNA—along a structurally weak location on chromosome 1 plays an important role in the development of neuroblastoma. Although CNVs have received much attention from genetics researchers over the last several years, this study was the first example of a specific CNV that predisposes people to cancer. The BARD1 study was published online in Nature Genetics on May 3, while the CNV study appears in tomorrow’s issue of Nature. The researchers made use of highly automated gene-analyzing technology at the Center for Applied Genomics at Children’s Hospital, directed by Hakon Hakonarson, M.D., Ph.D., a co-author of both studies. They used specimens collected from around the world through the Children’s Oncology Group. The BARD1 gene had already attracted attention from oncology researchers because it is associated with the gene BRCA1, which was the first discovered familial breast cancer gene. “Researchers have suspected that variants in BARD1 also increased the risk of breast cancer, but no one has found compelling evidence of this,” said Maris. “Instead, surprisingly, our genome-wide association studies found that BARD1 is a susceptibility gene for neuroblastoma, and perhaps other cancers as well.” Maris added that researchers are now working to understand the mechanism by which BARD1 gene variants act on developing nervous system cells to give rise to cancer during fetal or early childhood development. Maris’s second study, spearheaded by Dr. Sharon Diskin, also of The Children’s Hospital of Philadelphia, found that an inherited CNV located at chromosome 1q21.1 is associated with neuroblastoma. The chromosome region contains a large family of genes that are involved in the development of the nervous system, and the CNV they discovered changes how much of one particular gene is made within normal nerve and neuroblastoma cells. This study, Maris added, opens up a new area for studying the mechanisms of how CNVs may increase the risk of cancer. The current findings build on 2008 studies by Maris’s lab, one identifying the ALK gene as the major gene predisposing patients to the rare familial form of neuroblastoma, and the other identifying a region of chromosome 6 that increases the risk of the nonhereditary form of the disease. The ALK gene discovery has already led to a clinical trial led by Dr. Yael Mosse of The Children’s Hospital of Philadelphia. As gene studies continue to better define the genetic landscape of neuroblastoma, added Maris, pediatric oncologists can better develop more precise targeted treatments to improve survival and quality of life for children with this complex disease. The Cancer Center at Children’s Hospital has one of the nation’s largest research and clinical programs in pediatric oncology. DNA samples for both studies were provided by the Children’s Oncology Group, a multicenter collaborative research organization in which Maris chairs the committee overseeing basic and clinical research in neuroblastoma. A variety of funding sources supported both studies, including the National Institutes of Health, the Alex’s Lemonade Stand Foundation, the Evan Dunbar Foundation, the Rally Foundation, the Andrew’s Army Foundation, the Abramson Family Cancer Research Institute and the Giulio D’Angio Endowed Chair. Maris is also on the faculty of the University of Pennsylvania School of Medicine. Scientists from six other centers in addition to Children’s Hospital and the University of Pennsylvania contributed to the discovery or replication of the findings. ======================== Capasso et al, “Common variations in BARD1 influence susceptibility to high-risk neuroblastoma,” Nature Genetics, published online May 3, 2009. (http://dx.doi.org/10.1038/ng.374) Diskin et al, “Copy number variation at 1q21.1 associated with neuroblastoma,” Nature, published June 18, 2009. (http://dx.doi.org/10.1038/nature08035) About the Children's Hospital of Philadelphia The Children’s Hospital of Philadelphia was founded in 1855 as the nation’s first pediatric hospital. Through its long-standing commitment to providing exceptional patient care, training new generations of pediatric healthcare professionals and pioneering major research initiatives, Children’s Hospital has fostered many discoveries that have benefited children worldwide. Its pediatric research program is among the largest in the country, ranking second in National Institutes of Health funding. In addition, its unique family-centered care and public service programs have brought the 430-bed hospital recognition as a leading advocate for children and adolescents. For more information, visit http://www.chop.edu. Contact: John Ascenzi Phone: (267) 426-6055 Ascenzi@email.chop.edu
|
2022-12-16T15:41:39.481Z
|
136,406,128 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/0731684417709950",
"MAG": "2626125823",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Smoothed particle hydrodynamics is a Lagrangian meshless particle method, which can be applied to the modelling of complex flow in molding simulation. In the present work, firstly, by comparing the results of smoothed particle hydrodynamics and volume-of-fluid simulation for micro-scale flow within the fiber tow, the feasibility of smoothed particle hydrodynamics to simulate the flow in porous media was demonstrated. Secondly, the dual-scale flow in the dual-scale fiber preform during resin transfer molding was investigated using smoothed particle hydrodynamics simulation. The resin melt was modeled as fluid particles, and the fiber preform was regarded as dual-scale porous media depicted by fixed boundary particles. The smoothed particle hydrodynamics simulation described the evolution of the flow and the formation of the void. The effects of several factors on the size of the void were also studied. The results showed that the void size increased with the increase of vertical inter-tow dimension while decreased with the increasing resin velocity and viscosity.
|
2022-12-18T02:21:57.033Z
|
55,714,685 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1344/105.000002056",
"MAG": "1579602751",
"PubMedCentral": null
},
"license": "CCBYSA",
"status": "GOLD",
"url": "https://doi.org/10.1344/105.000002056"
}
|
A clear relationship exists between eustatic sea-level rises and falls recorded as cyclical depositional sequences and ammonite faunas during the Cenomanian-Santonian in the Iberian and West Portuguese basins. Most of the faunal turnovers correlate with stratigraphic intervals related to marine transgressions, maximum flooding of the shelf (locally associated to anoxic events), and marine regressions. Specifically, within each depositional sequence, three distinct and identical events of morphological change occur, involving ammonoids belonging to different groups. Transgressive sediments are characterized by moderately ornamented, inflated and evolute morphologies, which are replaced by smooth, involute and compressed oxycones (the most hydrodynamic shells) during maximum flooding (and to a lesser extent at the early highstand) of the sequences. The latter morphologies in turn are replaced by coarsely ornamented and evolute shells during late highstands. We conclude that ammonoid faunal analysis can be used to trace sea-level changes and provides an additional tool for sequence stratigraphy.
|
2022-12-24T21:19:42.143Z
|
34,781,008 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4268/cjcmm20161220",
"MAG": "3009017428",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This study was aimed to demonstrate preliminarily the effects and mechanisms of uremic clearance granule (UCG) ameliorating renal interstitial fibrosis (RIF) by regulating transforming growth factor (TGF)-β1/SnoN/Smads signaling pathway in vivo. Fifteen rats were randomly divided into 3 groups：the normal group,the model group and the UCG group. The rats with renal failure were induced by intragastric administration of adenine and unilateral ureteral obstruction (UUO). After modeling,the rats in the UCG group and in the other groups were intervened by intragastric administration of UCG and distilled water respectively during 3 weeks. The body weight and 24 h urinary protein excretion (Upro) in all rats were tested after drug administration. All rats were killed after drug administration for 3 weeks,blood and kidneys were collected and weighted,kidney appearance and renal morphological characteristics were observed. In addition,serum biochemical indices and the protein expressions of TGF-β1,SnoN,phosphorylated Smad2/3 (p-Smad2/3) and Smad7 in the kidney were evaluated respectively. The results indicated that,after the intervention of UCG,the general state of health,kidney appearance,serum creatinine (Scr),blood urea nitrogen (BUN),uric acid (UA),albumin (Alb),Upro and renal morphological change in model rats were improved in different degrees,respectively. Moreover,UCG down-regulated the protein expressions of TGF-β1 and p-Smad2/3,and up-regulated the protein expressions of SnoN and Smad7 in the kidney. In conclusion,UCG reduces extracellular matrix (ECM) synthesis and delays the progression of renal failure via possibly multi-targeting at regulating TGF-β1/SnoN/Smads signaling pathway in vivo.
|
2022-08-08T02:03:11.512Z
|
73,210,772 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1365-2982.1994.tb00166.x",
"MAG": "2099570493",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract Detection of peristalsis in the human small intestine has been limited in the past by both the available measurement techniques and the complexity of this activity. Recent developments in ambulant recording have provided a means of monitoring the occurrence of intestinal contractions at multiple sites in the small bowel, but the problem of complexity remains. Using digital data recorded from an intra‐luminal strain‐gauge transducer in the proximal gut, an algorithm was implemented to identify and classify contractile events within the small bowel. By modelling propagated activity the effect of varying transducer spacing and the number of transducers used was assessed. The question of variability of apparent velocity of peristaltic contractions was examined using successive cross‐correlation calculations to extract underlying phase differences between samples of 512 minutes of manometric recording over 150 mm of human small bowel. The effective velocity was found to have a median value of 14 mm sec‐1 and an inter quartile range of 12–18 mm see‐1). It is proposed that, in dynamically tracking variations in phase difference between adjacent recording sites, cross‐correlation techniques should be used to control the parameters used for the recognition of propagated contractile events and thereby improve the specificity of this process.
|
2022-09-14T17:10:35.103Z
|
43,828,567 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/MIEL.2010.5490492",
"MAG": "2004538518",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
It is shown that positron annihilation lifetime spectroscopy is a quite promising tool for nanostructural characterisation of humidity-sensitive spinel-type MgAl2O4 ceramics, the results being achieved provided four-component fitting procedure with arbitrary lifetimes is applied to treat mathematically the measured spectra. It is shown that Tao-Eldrup model is adequate for calculation of nanopore size in MgAl2O4 ceramics using lifetime values of the third and four components.
|
2022-12-02T21:35:07.855Z
|
2,063,187 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1504/IJTM.2004.005307",
"MAG": "2158588911",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Today, innovation systems are being elaborated in ever-wider areas of national space-economies. Of particular interest is the growth of academic study and practical policy towards assisting formation of regional innovation systems. Over 100 of these empirical studies have been documented worldwide and in the EU over 100 regional innovation strategies were implemented in the past decade. But new pressures upon existing innovation systems are coming from a globalising knowledge economy that favours metropoles and eschews peripheries. Now, new approaches to tackling innovation deficits are emerging ground-up in Europe that give insight into the real nature of competitiveness and the interlinked roles of science, research and innovation for the future.
|
2022-12-12T05:24:12.754Z
|
32,201,508 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1515/JPEM.2006.19.1.3",
"MAG": "1981447268",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
OBJECTIVES
To investigate a potential role of leptin and insulin-like growth factor (IGF)-I on fetal growth and metabolic function we determined plasma leptin and IGF-I concentrations in twins in relation to discordant fetal growth.
STUDY DESIGN
In studying monochorionic twins with inter-twin birth weight difference, we investigated the relative contribution of genetic (fetus) versus environmental (maternal/placental) factors on growth. Thirty-six sets of twins (14 with discordant growth, birth weight difference >15%) who had been treated for severe twin-to-twin transfusion syndrome (TTTS) by laser coagulation were studied. Cord blood samples were collected at birth and analyzed for IGF-I and leptin. Inter-twin differences (delta) of birth weight and head circumference were correlated to delta hormone levels.
RESULTS
An inter-twin correlation for leptin (r = 0.69; p <0.0001) and delta IGF-I (r = 0.49; p <0.0001) was found. delta birth weight correlated significantly with delta IGF-I (r = 0.67; p <0.0001) but not with delta leptin (r = 0.23; p = 0.19). delta IGF-I concentrations did not correlate with delta leptin (r = 0.18). delta head circumference correlated significantly with delta leptin (r = 0.47; p <0.01) and with delta IGF-I (r = 0.46; p <0.01). Using a multiple regression model with head circumference as dependent variable, adjusted for gestational age, head circumference remained significantly associated with higher leptin concentrations in all patients (p = 0.03).
CONCLUSION
IGF-I is a good indicator for fetal growth and brain development. Leptin seems to be mainly genetically determined but may play a role in fetal brain development and is not only an index for fetal fat mass.
|
2022-12-17T21:15:23.551Z
|
97,670,721 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1504/IJNT.2014.063795",
"MAG": "2062764126",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Tungsten trioxide (WO 3 ) nanospheres with diameter ranging from 10 nm to 500 nm were synthesised by a facile thermal oxidation process. By resistively heating metallic tungsten in oxygen atmosphere, WO 3 nanoparticles were produced in high yield. Optical, compositional, morphological and structural studies were performed by UV-VIS-NIR spectrophotometry, X-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM) and X-ray diffraction (XRD) studies. XPS studies revealed the formation of tungsten trioxide with oxygen deficiency. Analysis of the particle size (diameter) distribution of the as-deposited samples obtained from SEM micrograph exhibited a Gaussian-type distribution centred around 178 nm and characterised by a half width of 98.3 nm. As deduced from XRD analysis, the as-prepared tungsten trioxide (WO 3 ) nanoparticles were polycrystalline in nature and crystallised in the monoclinic phase. Electrophoretic deposition (EPD) was applied in coating the synthesised tungsten oxide nanoparticles onto fluorine doped tin oxide (FTO) coated quartz substrates for the fabrication of dye-sensitised solar cells (DSSC), with henna ( Lawsonia inermis ) as the natural organic dye. Nanoparticle suspension in double distilled water was used in the EPD process with an optimal electric field of 20 Vcm –1 at a current density of 1 mA/cm 2 . DSSCs developed using these films were tested through the measurement of their current density–voltage (J–V) and spectral photocurrent characteristics. A maximum IPCE of about 32% was obtained at around 450 nm.
|
2022-09-12T03:49:24.924Z
|
55,581,703 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/15567036.2010.514594",
"MAG": "2030781082",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The objective of this article was to review the emissions of carcinogenic air toxics from combustion of waste woods, especially in treated woods, such as Cu-impregnated woods, Cl-impregnated wood, painted wood, plywood, and particleboard. These air toxics discussed here include dioxins/furans, polychlorinated biphenyls, polycyclic aromatic hydrocarbons, volatile organic compounds, heavy metals, and other inorganics. Furthermore, the updated information about the governmental regulations for promoting waste woods as energy sources, as well as the environmental standards of carcinogenic air toxics from the emissions of waste-to-energy utilities in Taiwan, was also analyzed to demonstrate the case of waste-to-energy.
|
2022-07-28T01:49:58.063Z
|
253,104,337 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.24325/issn.2446-5763.v8i22p60-85",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "http://www.sadsj.org/index.php/revista/article/download/491/418"
}
|
O modal rodoviário é o meio de transporte de maior utilização no Brasil, portanto, necessita de investimentos em expansão e manutenção visto que participa ativamente na economia e no desenvolvimento do país. Isto requer agilidade e rapidez na execução e alteração dos projetos de estradas, sendo necessária uma alternativa para a evolução dos processos de um projeto. Neste trabalho é apresentada uma proposta de execução do projeto de uma estrada com a metodologia BIM (Building Information Modeling), utilizando-se de softwares como o AutoCad Civil 3D para a modelação e o Navisworks para a integração com o cronograma, onde será analisada a eficiência da aplicação da referida metodologia no projeto de estradas.
|
2022-10-28T00:22:27.268Z
|
253,901,687 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1079/cabicompendium.6327",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This datasheet on Apion decipiens covers Identity, Distribution.
|
2022-11-26T17:35:29.779Z
|
121,898,438 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1117/12.596674",
"MAG": "2012793650",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Diffraction Enhanced Imaging (DEI) is an x-ray phase contrast technique, which is showing great promise for a number of medical imaging problems. For a source it relies on a highly collimated flux of monochromatic x-rays, which is currently only available at synchrotron radiation facilities. Phase shifts occurring as the wave passes through the object are made visible using Bragg diffraction from a post-sample analyser optic. In early 2004 the DEI system on the bending-magnet beam line 7.6 of the Daresbury SRS was used for the first time to image a number of small medical specimens. This paper will report on the performance of the system and the results of these initial studies. A new DEI instrument is currently in the design phase. This facility will be integrated on wiggler station 9.4 on the SRS allowing access to shorter x-ray wavelengths and greater flux. A progress report on the design features and implementation of this system will be given.
|
2022-12-15T22:13:55.435Z
|
230,561,409 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.24180/ijaws.749476",
"MAG": "3112411067",
"PubMedCentral": null
},
"license": "CCBYNC",
"status": "GOLD",
"url": "http://dergipark.org.tr/tr/download/article-file/1141298"
}
|
Bean common mosaic virus (BCMV) ve Bean common mosaic necrosis virus (BCMNV) dunyada fasulye uretim alanlarinda yaygin olarak gorulen ve onemli verim kayiplarina neden olan hastalik etmenleridir. Bu hastalik etmenlerine karsi en etkili ve pratik mucadele yontemi ise dayanikli cesit kullanilmasidir. Bu kapsamda dunyada bu etmenlere karsi dayaniklilikla iliskili cok sayida gen ve bunlarla iliskili molekuler markor tespit edilmis olup islah calismalarinda yaygin olarak kullanilmaktadir. Bu calismada ise ulkemizde yaygin olarak yetistirilen 39 adet fasulye cesidinin BCMV ve BCMNV hastaliklarina karsi dayaniklilik kaynaklari farkli molekuler markorler (SW-13, SBD-5, ROC11, eIFE4) kullanilarak arastirilmistir. Elde edilen sonuclar test edilen fasulye genotiplerinden 11 adedinin tek bir dayaniklilik geni icerdigini gostermistir. Ayrica farkli dayaniklilik gen kombinasyonlari bakimindan 25 fasulye cesidinde I+bc-12 genlerinin bulundugu gorulmustur. Fransiz, Karabacak ve 40 Gunluk fasulye cesitlerinde ise dayanikliligin bc-12 ve bc-3 genleri ile kontrol edildigi tespit edilmistir. Yapilan calisma ile tespit edilen dayaniklilik genlerinin soz konusu hastaliklara karsi dayanikli islah materyallerinin gelistirilmesinde onemli birer dayaniklilik kaynagi olarak kullanilabilecekleri dusunulmektedir.
|
2022-12-24T17:28:48.300Z
|
21,563,607 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/PSCE.2011.5772546",
"MAG": "2095863402",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Distributed generation (DG), such as solar-energy-based photovoltaic (PV) systems, wind generation, and other renewable resources, is a quickly growing source of energy for today's power system. These assets pose challenges to grid reliability and power quality. One critical challenge is islanding (inadvertent system separation) detection, separation, and eventual resynchronizing. Research is underway to devise best practice methods for appropriate islanding control for all load and generation conditions. Wide-area measurements such as synchrophasors provide an accurate means to detect islanding conditions by enabling precise time-synchronized measurements at diverse locations. This paper presents a real-time islanding detection system for PV-based generation that is representative of many types of DG. The system utilizes synchrophasor data collected at the PV location and elsewhere in the system to detect the islanded condition. The paper shows how synchrophasors are used to isolate the DG during such conditions. It also discusses the real-time modeling and closed-loop testing of the synchrophasor-based islanding detection system, which includes the PV-based inverter and the power distribution system. The effectiveness of the system was experimentally tested on a live power system. An evaluation is also presented for using synchrophasors to resynchronize the islanded system.
|
2022-12-20T04:00:09.005Z
|
53,242,197 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/jnc.14623",
"MAG": "2900349812",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/jnc.14623"
}
|
X11/Mint 1 and X11‐like (X11L)/Mint 2 are neuronal adaptor protein to regulate trafficking and/or localization of various membrane proteins. By analyzing the localization of neuronal membrane proteins in X11‐, X11L‐, and X11/X11L doubly deficient mice with membrane fractionation procedures, we found that deficient of X11 and X11L decreased the level of glutamate receptors in non‐PSD fraction. This finding suggests that X11 and X11L regulate the glutamate receptor micro‐localization to the extrasynaptic region. In vitro coimmunoprecipitation studies of NMDA receptors lacking various cytoplasmic regions with X11 and X11L proteins harboring domain deletion suggest that extrasynaptic localization of NMDA receptor may be as a result of the multiple interactions of the receptor subunits with X11 and X11L regulated by protein phosphorylation, while that of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor subunits is not dependent on the binding with X11 and X11L proteins. Because the loss of X11 and X11L tends to impair the exocytosis, but not endocytosis, of glutamate receptors, NMDA receptors are likely to be supplied to the extrasynaptic plasma membrane with a way distinct from the mechanism regulating the localization of NMDA receptors into synaptic membrane region. Reduced localization of NMDA receptor into the extrasynaptic region increased slightly the phosphorylation level of cAMP responsible element binding protein in brain of X11/X11L doubly deficient mice compare to wild‐type mice, suggesting a possible role of X11 and X11L in the regulation of signal transduction pathway through extrasynaptic glutamate receptors.
|
2022-12-30T01:10:26.861Z
|
53,691,037 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1039/C8RA00414E",
"MAG": "2784645013",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We demonstrate the use of wafer-scale nanolithography based on block-copolymer (BCP) self-assembly for the fabrication of surfaces with enhanced wetting properties. All classes of wetting behaviour derived from the same BCP nanolithography step are demonstrated. An in situ etch mask is defined by self-assembly of polystyrene (PS) and dimethylsiloxane (PDMS) domains to form a predominantly hexagonal array with pitch size (72 ± 3) nm. The subsequent branched processing scheme, exclusively employing dry chemistry and reactive ion etching (RIE), allows the fabrication of nanoholes, nanopillars, or high aspect ratio nano-hoodoo features (overhang profile structures) with a diameter below 100 nm. The surfaces are finally functionalized with either hydrophobic surface chemistry by self-assembly from the precursor perfluorodecyltrichlorosilane (FDTS), or hydrophilic surface chemistry obtained by oxygen plasma treatment. The different texture and surface chemistry configurations are characterized with respect to their wetting properties with water, alkanes and organic oils. While, both nano-pillar and nano-hole surfaces feature excellent superhydrophobic properties with water contact angles (WCAs) exceeding 170° and roll-off angles below 5°, only the nano-pillar surfaces exhibit convincing superhydrophilicity with WCAs below 5°. The repellency of low surface tension liquids known as amphiphobicity is demonstrated for the nano-hoodoo surfaces.
|
2022-12-30T00:48:24.320Z
|
57,383,818 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1086/604670",
"MAG": "2098912445",
"PubMedCentral": "7107965"
},
"license": null,
"status": "BRONZE",
"url": "https://academic.oup.com/cid/article-pdf/48/8/1003/955839/48-8-1003a.pdf"
}
|
Abstract Un Grupo de Expertos de la Sociedad de Enfermedades Infecciosas de los Estados Unidos de América elaboró las guias para el tratamiento de personas infectadas por el virus de la influenza. Estas guias basadas en datos y pruebas cientificas comprenden el diagnóstico, el tratamiento y la quimioprofilaxis con medicamentos antivirales, además de temas relacionados con el control de brotes de influenza estacional (interpandémicas) en ámbitos institucionales. Están destinadas a los médicos de todas las especialidades a cargo de la atención directa de pacientes porque los médicos generales que atienden una gran variedad de casos son los que se enfrentan con la influenza, frecuente en el ámbito comunitario durante la temporada de influenza.
|
2023-01-01T23:28:35.021Z
|
171,076,846 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1590/S0101-31732012000300001",
"MAG": "2065705540",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Neste primeiro fasciculo regular de 2013, TRANS/FORM/ACAOoferece ao leitor dez artigos e uma traducao. Toda essa producao esta limitadaa filosofia moderna e a contemporânea. Dentre os modernos temos artigosdedicados a Locke, Rousseau, Hegel e a traducao do texto "Sobre o uso deprincipios teleologicos na filosofia", de Immanuel Kant. De contemporâneatemos artigos dedicados a Bergson (dois), a Heidegger, a Albert Camus, a PaulRicoeur, a John Rawls e a memetica em Richard Dawkins e Daniel Dennett.
|
2022-03-11T08:33:19.929Z
|
247,831,189 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.33448/rsd-v11i4.27438",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://rsdjournal.org/index.php/rsd/article/download/27438/24137"
}
|
In current study, the production of biosurfactant by Cunninghamella elegans UCP 0542 in food industry waste-based medium was investigated as a biotechnological strategy to reduce the bioprocess costs. Cultivation of the Mucoralean fungus was performed in 3 L Fernbach flasks containing 1.5 L of effective volume of medium composed by 2% instant noodle waste, 2% corn steep liquor and 0.5% post-frying soybean oil, with carbon/nitrogen ratio of 30:1. Fermentations were carried out during 96 h and 28ºC, at 150, 180 and 200 rpm, in order to evaluate the influence of orbital agitation in biosurfactant production. The properties of surface tension reduction, emulsification and dispersion were investigated. According to the obtained results, C. elegans produced biosurfactant in sustainable medium, reducing the surface tension from 71 to 27.5 mN/m after cultivation at 200 rpm. Biotensoactive produced in this condition formed stable emulsions with engine oil and burnt engine oil (emulsification index of 100%) and showed 48.39 cm² of oil dispersion area (ODA) with burnt engine oil. The biomolecule was isolated by different methodologies, reaching a maximum yield of 2.1 g/L with ethanol. The biosurfactant produced by C. elegans exhibited excellent potential for application in bioremediation processes considering its promising properties as a surface tension reducing agent, emulsifying and dispersing action of petroderivatives.
|
2022-11-17T02:19:58.664Z
|
191,320,895 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1051/SHSCONF/20120100305",
"MAG": "1967550109",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Avec la democratisation des savoirs, dont l'evolution s'accentue grâce a l'utilisation de la Toile, un nombre croissant de documents specialises peut etre trouve en ligne. Cette situation est typique de differents domaines de specialite (biomedical, juridique, energetique, telecommunication ...). Si de tres nombreux documents peuvent ainsi etre trouves, leur contenu n'est pas pour autant accessible a tous les utilisateurs. En effet, les documents vulgarises et specialises co-existent et, dans ce dernier cas, contiennent des informations tres techniques et difficiles a comprendre par les non experts. Des alors, l'indication sur le degre de specialisation de ces documents est une information importante, car elle permet justement de guider les utilisateurs vers des contenus qui leur sont plus appropries. Dans ce travail, nous montrons qu'il est possible d'exploiter les informations morphologiques des documents de sante afin d'effectuer une distinction automatique efficace (avec des performances souvent superieures a 90 %) de la specialisation de ces documents. Nous effectuons une analyse quantitative et qualitative du materiel morphologique. Nous effectuons egalement une comparaison entre l'exploitation du materiel morphologiques et le materiel lexical. Nous exploitons plusieurs outils du Traitement Automatique des Langues qui nous permettent ainsi d'acceder au niveau morphologique des mots des documents et de nous concentrer de cette maniere sur leur structure morphologique et semantique.
|
2022-11-25T01:12:46.484Z
|
8,119,260 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1113/jphysiol.2006.125914",
"MAG": "1539779735",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://physoc.onlinelibrary.wiley.com/doi/pdfdirect/10.1113/jphysiol.2006.125914"
}
|
It has been shown that the activation of Gq‐coupled receptors (GqPCRs) in cardiac myocytes inhibits the G protein‐gated inwardly rectifying K+ current (IGIRK) via receptor‐specific depletion of phosphatidylinositol 4,5‐bisphosphate (PIP2). In this study, we investigated the mechanism of the receptor‐mediated regulation of IGIRK in acutely isolated hippocampal CA1 neurons by the muscarinic receptor agonist, carbachol (CCh), and the group I metabotropic glutamate receptor (mGluR) agonist, 3,5‐dihydroxyphenylglycine (DHPG). IGIRK was activated by the GABAB receptor agonist, baclofen. When baclofen was repetitively applied at intervals of 2–3 min, the amplitude of the second IGIRK was 92.3 ± 1.7% of the first IGIRK in control. Pretreatment of neurons with CCh or DHPG prior to the second application of baclofen caused a reduction in the amplitude of the second IGIRK to 54.8 ± 1.3% and 51.4 ± 0.6%, respectively. In PLCβ1 knockout mice, the effect of CCh on IGIRK was significantly reduced, whereas the effect of DHPG remained unchanged. The CCh‐mediated inhibition of IGIRK was almost completely abolished by PKC inhibitors and pipette solutions containing BAPTA. The DHPG‐mediated inhibition of IGIRK was attenuated by the inhibition of phospholipase A2 (PLA2), or the sequestration of arachidonic acid. We confirmed that DHPG eliminated the inhibition of IGIRK by arachidonic acid. These results indicate that muscarinic inhibition of IGIRK is mediated by the PLC/PKC signalling pathway, while group I mGluR inhibition of IGIRK occurs via the PLA2‐dependent production of arachidonic acid. These results present a novel receptor‐specific mechanism for crosstalk between GqPCRs and GABAB receptors.
|
2022-12-03T12:22:01.531Z
|
33,793,838 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1445-5994.2009.02102.x",
"MAG": "1842909076",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Background: Nosocomial diarrhoea is common and its investigation carries a significant healthcare cost. This study aimed to determine the utility of faecal lactoferrin (FL), a readily measurable marker of intestinal inflammation, in hospitalized patients with diarrhoea.
|
2022-12-10T09:01:21.885Z
|
70,557,042 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.7197/cmj.v32i1.1008000219",
"MAG": "1656802829",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Ozet Patau sendromu canli dogumlarda 1/12000-29000 oraninda gorulmektedir. Prenatal tani onem gostermekle birlikte ileri anne yasi ile bu sendromun gorulme sikligi artmaktadir. Trizomi 13 ya da Patau sendromu, Trizomi 21 (Down sendromu) ve Trizomi 18’den (Edward sendromu) sonra en yaygin olarak gorulen ucuncu otozomal trizomili kromozom duzensizligidir. Bu calismamizda 22 haftalik gebeligi bulunan hastanin yapilan USG sonucunda fetuste omfalosel ve yarik damak tespit edilen olguya amniyosentez analizi yapilmis ve fetuste 47, XY, +13 karyotipi saptanmistir. Aile onayi da alinarak gebelik sonlandirilmistir. Aileye olasi sonraki gebeliklerinde gebelik oncesi danismanlik hizmeti icin klinigimize basvurmasi onerilmistir. Anahtar sozcukler: Trisomi 13, Patau sendromu, omfalosel, yarik damak, yarik dudak, polidaktili Abstract: Trisomy 13, or Patau syndrome, represents the third autosomic trisomy in order of frequency, after trisomy 21 (Down syndrome) and trisomy 18 (Edwards syndrome), with a prevalence at birth estimated as between 1:12000 and 1:29000. In this study, we are presenting the results of cytogenetic analysis and clinic assessment in fetus of a woman at 22 weeks gestation. Amniocentesis was performed and a karyotype of (47, XY,+13) was determined at 22th weeks of gestation. The pregnancy was terminated with the permission of the parents. We suggested the parents to admit our clinic for the preconceptional counseling. Keywords: Trisomy 13, Patau syndrome, omphalosel, cleft lib, cleft palate, polidactily
|
2022-02-11T11:28:14.580Z
|
24,625,625 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1074/jbc.M113.545293",
"MAG": "2018360853",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Background: Unsaturated glucuronyl hydrolases (UGL) from GH88 are bacterial enzymes involved in the degradation of glycosaminoglycans and are virulence factors. Results: Mechanistic data inconsistent with the currently accepted mechanism of UGL are presented. Conclusion: A revised mechanism is proposed to explain all mechanistic data published to date. Significance: Understanding of the mechanism of UGL may allow design of bacteriostatic agents. Experiments were carried out to probe the details of the hydration-initiated hydrolysis catalyzed by the Clostridium perfringens unsaturated glucuronyl hydrolase of glycoside hydrolase family 88 in the CAZy classification system. Direct 1H NMR monitoring of the enzymatic reaction detected no accumulated reaction intermediates in solution, suggesting that rearrangement of the initial hydration product occurs on-enzyme. An attempt at mechanism-based trapping of on-enzyme intermediates using a 1,1-difluoro-substrate was unsuccessful because the probe was too deactivated to be turned over by the enzyme. Kinetic isotope effects arising from deuterium-for-hydrogen substitution at carbons 1 and 4 provide evidence for separate first-irreversible and overall rate-determining steps in the hydration reaction, with two potential mechanisms proposed to explain these results. Based on the positioning of catalytic residues in the enzyme active site, the lack of efficient turnover of a 2-deoxy-2-fluoro-substrate, and several unsuccessful attempts at confirmation of a simpler mechanism involving a covalent glycosyl-enzyme intermediate, the most plausible mechanism is one involving an intermediate bearing an epoxide on carbons 1 and 2.
|
2022-12-14T23:57:34.135Z
|
17,214,115 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1523/JNEUROSCI.2007-14.2014",
"MAG": "2070381140",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
After complete nerve transection, a major challenge for regenerating peripheral axons is to traverse the injury site and navigate toward their original trajectory. Denervated Schwann cells distal to the lesion site secrete factors promoting axonal growth and serve as an axonal substrate, yet whether Schwann cells also actively direct axons toward their original trajectory is unclear. Using live-cell imaging in zebrafish, we visualize for the first time how in response to nerve transection distal Schwann cells change morphology as axons fragment, and how Schwann cell morphology reverses once regenerating growth cones have crossed the injury site and have grown along distal Schwann cells outlining the original nerve path. In mutants lacking Schwann cells, regenerating growth cones extend at rates comparable with wild type yet frequently fail to cross the injury site and instead stray along aberrant trajectories. Providing growth-permissive yet Schwann cell-less scaffolds across the injury site was insufficient to direct regenerating growth cones toward the original path, providing compelling evidence that denervated Schwann cells actively direct regenerating axons across the injury site toward their original trajectory. To identify signals that guide regenerating axons in vivo, we examined mutants lacking the deleted in colorectal carcinoma (DCC) guidance receptor. In these dcc mutants, a significant fraction of regenerating motor axons extended along aberrant trajectories, similar to what we observe in mutants lacking Schwann cells. Thus, Schwann cell and dcc-mediated guidance are critical early during regeneration to direct growth cones across the transection gap and onto their original axonal trajectory.
|
2022-12-20T23:53:53.951Z
|
216,659,349 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21257/SG.91",
"MAG": "3013727857",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The EU Return Directive has been adopted 10 years ago. The following article analyzes whether the system that has been created has met the objectives set in 2008. It will especially focus on shortcomings hat can be illustrated by CJEU judgments. The 2018 proposal for a recast of the Directive will also be studied. The article comes to the conclusion that it will be inevitable to go back to the start and think about a better legal regime tackling the issue of returning irregular migrants.
|
2022-02-08T02:12:18.849Z
|
237,957,260 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.17165/tp.2021.1-2.9",
"MAG": "3178849679",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "http://publicatio.uni-sopron.hu/2191/1/TP-2021-1-2-09-Frang_G-article.pdf"
}
|
Magyarországon a rendszerváltozás idejétől újból hivatalosan is működhetnek az egyházi intézmények, közöttük az egyházi óvodák. Örvendetes, hogy számuk folyamatosan gyarapszik. Azonban az ezzel járó gyermek- és a nevelőlétszám emelkedése új módszertani és képzési kérdéseket vet fel. Korunk sajátos kihívása, hogy miként lehet a teológiát és a pedagógiát össze-hangolva ezen egyházi intézmények számára szakembereket képezni, s hogyan lehet az 1945 után megszakadt, háttérbe szorított módszertani fonalat újra felvenni. E kérdésekre keres válaszokat a tanulmány, bemutatva a Soproni Egyetem Benedek Elek Pedagógiai Karán bevezetett Hitéletre nevelés specializációt, valamint az ugyane címet viselő pedagógus szakvizsgás képzést.
|
2022-02-07T20:39:23.774Z
|
97,765,657 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/PSSC.200777622",
"MAG": "2058464693",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We theoretically investigate entangled-photon generation via biexciton in a planar microcavity. When the exciton-photon coupling is comparable to the biexciton binding energy, the biexciton can be stably coupled with the cavity photons (referred to as a cavity biexciton). Entangled photons are generated by the cascade decay of the cavity biexciton. We show that high-efficient generation of entangled photons can be achieved when the superposition state of a cavity biexciton and two cavity polaritons formed by unbound two-exciton states is realized. (© 2008 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim)
|
2022-07-30T22:50:43.061Z
|
29,228,546 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/ic101849h",
"MAG": "2316495382",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Reactions of lanthanide(III) perchlorate (Ln = Dy, Tb, and Gd), nickel(II) acetate, and ditopic ligand 2-(benzothiazol-2-ylhydrazonomethyl)-6-methoxyphenol (H(2)L) in a mixture of methanol and acetone in the presence of NaOH resulted in the successful assembly of novel Ln(2)Ni(2) heterometallic clusters representing a new heterometallic 3d-4f motif. Single-crystal X-ray diffraction reveals that all compounds are isostructural, with the central core composed of distorted [Ln(2)Ni(2)O(4)] cubanes of the general formula [Ln(2)Ni(2)(μ(3)-OH)(2)(OH)(OAc)(4)(HL)(2)(MeOH)(3)](ClO(4))·3MeOH [Ln = Dy (1), Tb (2), and Gd (3)]. The magnetic properties of all compounds have been investigated. Magnetic analysis on compound 3 indicates ferromagnetic Gd···Ni exchange interactions competing with antiferromagnetic Ni···Ni interactions. Compound 1 displays slow relaxation of magnetization, which is largely attributed to the presence of the anisotropic Dy(III) ions, and thus represents a new discrete [Dy(2)Ni(2)] heterometallic cubane exhibiting probable single-molecule magnetic behavior.
|
2022-09-23T23:41:14.188Z
|
3,661,638 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/BCR.0b013e3181bfb810",
"MAG": "1992242186",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The purpose of this study was to assess if the healing course of burn wounds of indeterminate depth can be predicted based on serial in vivo reflectance-mode confocal microscopy (RMCM) analysis. Twenty-four patients (mean age, 33.1 ± 11.4 years; mean burn size: 6% TBSA) were investigated at 12, 36, and 72 hours after burn of indeterminate depth and retrospectively grouped into healing group (HG: 16 patients) and nonhealing group (NHG: eight patients). Noninjured skin served as controls. The following parameters were assessed: quantitative blood cell flow (BCF), basal layer thickness (BLT), and inflammatory cells. At 12 hours postburn, BCF increased to 101.67 ± 7.64 cells/min in HG vs 85 ± 50 cells/min in NHG compared with controls (56.5 ± 2.3 cells/min). At 36 and 72 hours, BCF increased to 115 ± 10 cells/min and 125 ± 50 cells/min in HG vs decreased to 80 ± 5 cell/min and 75 ± 5 cells/min in NHG (P < .05). At 12 hours postburn, BLT increased to 19.43 ± 0.93 &mgr;m in HG vs 29 ± 1 &mgr;m in NHG compared with controls (15.40 ± 0.60 &mgr;m, P < .05). In HG, further gradual increase of BLT to 20 ± 1 &mgr;m (36 hours) and 21 ± 1 &mgr;m (72 hours) was observed, whereas BLT was destroyed after 36 hours in NHG. Qualitative assessment found insignificant amount of IC in controls and low amount in HG until 72 hours postburn, whereas progressive increase in IC from low amount (12 hours) to numerous (36 hours) and massive (72 hours) was observed in NHG. RMCM enables simultaneous evaluation of microcirculation, histomorphology, and inflammatory cell trafficking in burn wounds. RMCM may help to predict whether burns of indeterminate depth have the potential to heal and can be a valuable tool to clinicians to guide early therapeutic decision-making process in burn patients.
|
2022-12-17T14:27:25.714Z
|
122,064,076 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1061/(ASCE)0733-9453(1997)123:1(32)",
"MAG": "2161731567",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Modeling of linear features, particularly straight lines and circles, in two-dimensional (2D) and three-dimensional (3D) spaces, is developed, with specific consideration of independent descriptors. This is followed by the derivation of the four-, six-, and eight-parameter 2D transformations in terms of the line and circle parameters, as well as 3D linear transformation. Minimum configuration, redundant cases, and restrictions regarding special cases are carefully noted and are compared to the cases of using points only. Many useful geometric constraints between linear features, which provide significant information, are identified and corresponding equations are developed. Constraints involving relative geometric information relating features to each other are considered in addition to those constraints relating features to the reference coordinate system. Finally, the standard point-based photogrammetric collinearity equations are replaced by those based on correspondence between image and object linear features. Results are presented describing experiments where the coordinates of points are perturbed using Gaussian random noise to emulate real data. Several thoughts are listed regarding the future applications of this research in practice.
|
2022-12-19T23:14:44.944Z
|
161,268,474 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4000/communication.351",
"MAG": "1571379960",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://doi.org/10.4000/communication.351"
}
|
Cet ouvrage se presente sous la forme d’un livre collectif divise en parties et chapitres. Il a ete realise a l’issue du colloque franco-canadien qui s’est tenu a Lyon, a l’Ecole nationale superieure des sciences de l’information et des bibliotheques, du 8 au 11 decembre 2002. L’objet du colloque etait de confronter les points de vue relatifs aux defis de la publication sur le Web. Comme beaucoup d’actes de ce type, la multiplicite des sujets a traiter et la pluridisciplinarite des approches ...
|
2022-02-08T22:19:07.927Z
|
60,151,606 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.7583/jkgs.2011.11.2.115",
"MAG": "922116372",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this paper, we will introduce some method about retrieving suitable images to game or adjusting game difficulty in enjoying some contents like mini-game. It will use the technology about extracting color and texture features in content-based image retrieval in image processing. So in card game, it select card image automatically. And by controlling seed image number, we can adjusting game difficulty. Through the experiment, it shows that our image retrieval method can retrieve more useful images that can be used in game than others.
|
2022-05-14T17:06:06.018Z
|
209,610,419 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/0471264180.OS040.11",
"MAG": "1587537170",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
2,5-Dihydro-2,5-dimethoxyfuran
product: 2,5-Dihydro-2,5-dimethoxyfuran
Keywords:
addition, to CCCC;
replacement reactions, miscellaneous;
furan
|
2022-07-10T03:13:09.491Z
|
8,801,300 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2139/ssrn.2169310",
"MAG": "2140323503",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
On December 28, 2007, China delivered its application and initial offer for acceding to the Agreement on Government Procurement (GPA) to the WTO Secretariat. The negotiation will define China's openness in an economically and politically significant market: the government procurement for consumption and investment. As a plurilateral agreement under the WTO, the GPA accession negotiation follows the way of WTO accession negotiation. Like the WTO agreements, the GPA also contains general principles and rules over government procurement, as well as specific commitments of individual parties. The negotiation will take place bilaterally between the acceding member and interested parties, then going to the multilateral phase. With the 15-year experience of tough WTO membership talks, China is supposed to be comfortable about copying the previous negotiation approach. In addition, the WTO accession has proven to be successful. The Chinese government is also launching a series of events to commemorate the achievements in the 10th anniversary of China's WTO membership.However, after the first three years, China's GPA negotiation have shown a number of different features from WTO negotiation. In particular, China is taking a quite different organizational structure in this negotiation in terms of political leadership, organizational arrangements, academic and public involvement. Without a formal political process of interest groups as democracies, these organizational aspects actually represent a Chinese-characteristic trade politics. They have influenced the up-to-date process of the negotiation and will influence the future results as well. The paper will try to describe the organizational aspects of China's GPA accession negotiation in comparison with WTO negotiation from a variety of perspectives, and to discover why they would be so different and how these differences would impact the coming negotiation and its results.
|
2022-09-12T04:13:52.907Z
|
187,467,800 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.22409/CONTRACAMPO.V0I31.702",
"MAG": "2738269521",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
O artigo sintetiza reflexoes sobre o talk show
brasileiro a partir de como a MTV Brasil
consolidou um modo de reproducao do genero
com o programa “Gordo a Go-Go”, exibido
entre 2000 e 2005. O desafio metodologico
foi empreender uma analise que considere,
de modo articulado, materialidades do
programa, seus contextos especificos e
discursos que circularam na imprensa de
modo a rastrear definicoes e atritos que nos
ajudem a compreender a historia do talk
show no pais. Baseado na premissa de que o
genero televisivo e uma construcao cultural
que se constitui pelo permanente processo de
continuidades e descontinuidades, o estudo
demonstra como rupturas de marcas de genero
sao dimensoes de disputa por convencoes.
|
2022-01-27T18:38:02.661Z
|
121,702,187 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1063/1.1646159",
"MAG": "2040145265",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The Naval Research Laboratory (NRL) has recently developed a 3–10 kW average, 80 kW peak power 94 GHz radar with scanning capability, WARLOC (W Band Advanced Radar for Low Observable Control). This radar is powered by a gyroklystron developed by a team led by NRL. One application has been to image clouds. New capabilities of WARLOC include imaging with greatly improved sensitivity and detail as well as the ability to detect much lower cloud returns. At short scale lengths (∼10 m), the cloud reflectivity has a speckle pattern indicating that it is governed at least in part by stochastic processes. Here WARLOC is used to measure correlation functions and turbulence spectra in clouds. In the inertial range, the Kolmogorov prediction for the correlation function index (2/3) agrees well with the data, but the assumption of isotropy does not. Furthermore, for longer scale lengths, the fluctuations appear to be wave like in the vertical direction, but not in the horizontal direction.
|
2022-12-10T13:05:05.563Z
|
59,520,887 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4319/lo.2005.50.6.1740",
"MAG": "2101682795",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
We examined the effect of in‐channel flow obstructions such as vegetation and coarse woody debris (CWD) on transient storage and nutrient uptake by using experimental channel manipulations. Transient storage and nutrient uptake were measured under existing conditions in a vegetated agricultural stream and a shaded blackwater stream, and measurements were repeated after removal of vegetation and CWD. Removal of vegetation and CWD decreased transient storage area (As) by 61% and 43% in the agricultural and blackwater streams, respectively, and decreased the portion of median travel time owing to transient storage (Fmed) by 45% and 56%, respectively. Flow baffles were then added to create in‐channel transient storage in both streams. Baffles increased As 227% and 119% for the agricultural and blackwater streams, respectively, and increased Fmed 309% and 132%, respectively. Ammonium and PO4 uptake for the blackwater stream, determined by using nutrient addition experiments and expressed as the mass transfer coefficient (Vf), decreased after CWD removal by 88% and 38%, respectively. Ammonium Vf in the blackwater stream increased 143‐fold after baffles were installed, and PO4 Vf increased from — 1.7 to 53 mm min−1. Nutrient uptake rates were not calculated for the agricultural stream because sediment disturbance inadvertently altered the sediment‐water column nutrient equilibrium. Results from both streams demonstrate that in‐channel transient storage, rather than hyporheic storage, can be a substantial portion of overall transient storage in streams. In‐channel transient storage influenced nutrient uptake in a blackwater stream, although these results could not be corroborated with data from the agricultural stream.
|
2022-12-17T09:13:15.160Z
|
249,649,490 |
{
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"ArXiv": null,
"DOI": "10.3390/biology11081113",
"MAG": null,
"PubMedCentral": "9332626"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2079-7737/11/8/1113/pdf?version=1658828100"
}
|
The increasing incorporation of omics technology into clinical and translational medicine presents challenges to end users of the large and complex datasets that are generated by these methods. A particular challenge in genomics is that the nomenclature for genes is not uniform between large genomic databases or between commonly used genetic analysis tools. Furthermore, outdated genomic nomenclature can still be found amongst scientific communications including peer-reviewed manuscripts. Therefore, a web application (GeneToList) was developed to assist is gene ID conversion and alias matching, with a specific focus on achieving a user-friendly interface for the non-bioinformatics-savvy scientist. Availability and implementation GeneToList is available at https://www.genetolist.com/. The tool is a web application that is compatible with many standard browsers. Contact Joshua.Breidenbach@UToledo.edu or support@genetolist.com
|
2022-12-21T00:51:19.663Z
|
8,795,464 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/INFOCOM.2008.43",
"MAG": "2114252197",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Denial-of-service (DoS) attacks remain a challenging problem in the Internet. By making resources unavailable to intended legitimate clients, DoS attacks have resulted in significant loss of time and money for many organizations, thus, many DoS defense mechanisms have been proposed. In this paper we propose live baiting, a novel approach for detecting the identities of DoS attackers. Live baiting leverages group-testing theory, which aims at discovering defective members in a population using the minimum number of dasiadasiatestspsilapsila. This leverage allows live baiting to detect attackers using low state overhead without requiring models of legitimate requests nor anomalous behavior. The amount of state needed by live baiting is in the order of number of attackers not number of clients. This saving allows live baiting to scale to large services with millions of clients. We analyzed the coverage, effectiveness (detection time, false positive and false negative probabilities), and efficiency (memory, message overhead, and computational complexity) of our approach. We validated our analysis using NS-2 simulations modeled after real Web traces.
|
2022-12-29T16:01:32.929Z
|
222,570,553 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3760/CMA.J.ISSN.1673-436X.2007.07.003",
"MAG": "3031231811",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
有关β2-肾上腺素能受体(β2-AR)基因与哮喘的相关研究大多数都集中于两个常见的编码区非同义突变,即Arg16Gly和Gln27Glu,研究的结果存在着大量的不一致性.近来对β2-AR单倍型的研究表明,β2-AR基因的多个SNP以及它们的相互作用即单倍型在哮喘发病中比这两个常见的多态性更为重要.最近三个meta-分析表明Arg16Gly以及Gln27Glu多态性与哮喘发病无关,尽管已有研究证明它们与哮喘的其它表型相关.β2-AR基因不是哮喘发生的主要危险因素,但其多态性在决定药物反应性方面很可能重要的.本文综述了近年来有关β2-AR基因多态性在哮喘研究中的作用和这些研究的局限性以及将来β2-AR基因多态性的研究方向。
|
2022-02-08T00:50:36.569Z
|
17,899,888 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/PCICON.2006.359702",
"MAG": "2541499472",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper demonstrates the design and implementation of smart on-line fast load shedding to maintain system stability and operation when a major generating unit is suddenly tripped. The design stage included load flow and transient stability study cases to determine system stability limits, transient frequency variation curves and transient voltage profiles. Numerous outage scenarios that cover all possible operating conditions are simulated and key system stability parameters are identified. A fast load shedding priority list has been provided by system operations and has been included as needed into transient stability simulation cases to maintain system stability and generation/load balance. Fast load shedding logic diagrams are developed with triggering parameters including generating unit breaker status and on-line frequency measurements. On-line measurements of system generation, tie line flow and loads are continuously monitored and fed into a PLC system that processes information and issues load shedding trip signals to maintain balanced generation/load and stability. This fast load shedding scheme has been tested in real time outages several times, and proved to be accurate and in agreement with transient stability simulation results. Since its implementation, this load shedding scheme has successfully saved the oil field power system from total shutdown and maintained system operation after sudden tripping of major generating units
|
2022-02-13T00:05:36.722Z
|
240,874,986 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.37142/1993-8222/2019-2(46)59",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
Король Р. Н. Особенности основных технологических и конструктивных параметров стационарной клети ХПТР для обеспечения непринудительного процесса холодного редуцирования труб // Вестник ДГМА. – 2019. – № 2 (46). – C. 59–63.
Способ холодного редуцирования труб на станах ХПТР применяется при изготовлении труб с особо высокой точностью по толщине стенки, наружному и внутреннему диаметрам, а также при изготовлении особо толстостенных труб методом «сочленения». К недостаткам применяемых рабочих клетей станов ХПТР можно отнести то, что протяженность хода подвижного сепаратора, в котором осуществляется деформация заготовки, меньше длины хода рабочей клети, а также подвижные части клети имеют большой вес, что, в свою очередь, ограничивает скорость прокатки, снижая тем самым производительность стана. Подвижная обойма рабочей клети обладает низкой жесткостью, что обуславливает значительную величину упругой деформации системы «рабочий инструмент – прокатная клеть». Это подтверждается расчетами, приведенными в работе. Использование стационарной клети стана ХПТР с опорными катками для редуцирования особотонкостенных труб в начальный момент закатки переднего конца трубы может привести к его постоянному сплющиванию из-за большого веса опорных катков и рабочих роликов, нарушая, таким образом, стабильность процесса прокатки. К недостаткам клети следует отнести и трудоемкость изготовления опорных катков. Целью работы является определение технологических и конструкционных особенностей стационарной клети стана ХПТР для обеспечения непринудительного процесса холодного редуцирования труб. Для обеспечения вышеуказанного было предложено исключить из конструкции клети опорные катки и обеспечить свободное качение роликов по рабочему конусу, осуществить так называемый непринудительный процесс прокатки – при движении сепаратора ролики приводятся во вращение силами трения в очаге деформации, а их цапфы свободно перекатываются по рабочей калиброванной поверхности опорных планок. Применение стационарной клети стана ХПТР со сборным роликом с элементами качения позволяет добиться стабильности процесса прокатки при холодном редуцировании тонкостенных труб, а при изготовлении особо толстостенных труб методом «сочленения» – обеспечить высокое качество поверхности и длительную стойкость рабочего инструмента за счет непринудительного ведения процесса прокатки.
|
2022-05-10T00:49:35.441Z
|
235,744,222 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.14701/ahbps.BP-OP-4-5",
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},
"license": null,
"status": null,
"url": null
}
|
Introduction
The da Vinci surgical system released its new pure single-port platform, the da Vinci SP, offering improvements and refinements such as articulating instruments for established robotic single-site procedures. We describe our institution's experience with robotic single site cholecystectomy utilizing the new da Vinci single-port (SP) robotic system and compare the results with the previous da Vinci Si/Xi system.
Methods
We reviewed the medical records and compared the perioperative outcomes of patients who underwent robotic single site cholecystectomy using the da Vinci SP model with the previous Si and Xi models.
Results
Of the 238 patients, there were 120 and 118 patients in the SP and Si/Xi group, respectively. The mean age of patients in the SP group was 48.7 years which was significantly higher than the Si/Xi group (p = 0.002). However, the BMI of patients in both groups was similar. In both groups, the most common indication for cholecystectomy was gallbladder stone. However there more patients diagnosed with acute cholecystitis in the SP group (4.2%). The mean docking time (3.20 ± 1.40 min), console time (21.63 ± 13.34 min) and total operative time (48.42 ± 18.33 min) was significantly shorter in the SP group. However the conversion rate, complication rate and hospital stay was similar between the 2 groups.
Conclusions
Robotic single site cholecystectomy using da Vinci SP is safe and feasible. Due to its refinements, it requires less time for preparation and operation than the previous Si or Xi models and has showed promise to include more challenging indications such as acute cholecystitis.
|
2022-07-31T04:34:43.538Z
|
120,821,770 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1063/1.2914355",
"MAG": "1997366710",
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},
"license": null,
"status": null,
"url": null
}
|
Twenty‐five years ago when I was a graduate student in physics, I was drafted into the Army and sent to Eniwetok in the Marshall Islands. There was plenty of spare reading time for an army private on this tiny atoll, and I had taken along a paperback copy of Fred Hoyle's Frontiers of Astronomy. Hoyle made astronomy exciting and I began to wonder whether I might find a way to enter the field.
|
2022-04-03T23:16:18.193Z
|
20,005,545 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.3109/09638237.2014.951486",
"MAG": "2118970138",
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},
"license": null,
"status": null,
"url": null
}
|
Abstract Background: Medicaid is the largest payer for mental health (MH) services. Aims: This study examines associations between Medicaid provisions and the MH industry composition. Methods: Medicaid data derived from the Centers for Medicare and Medicaid Services. MH facility gross payroll and occupational employment data derived from the Bureau of Labor Statistics. State fixed-effects regression models are performed to examine associations. Results: In the 1999–2009 period, per-capita gross payroll gains are largest for residential MH and substance abuse (SA) facilities and MH practitioner offices, followed by MH clinics and physician offices. Likewise, occupational employment gains per 100 000 people are largest for MH and SA social workers and MH counselors, followed by psychiatrists and psychologists. The Medicaid beneficiary rate is related with gross payroll gains at residential MH and SA facilities (p < 0.001) and MH clinics (p < 0.001), and with employment gains for MH and SA social workers (p < 0.001) and MH counselors (p < 0.001). Smaller effect sizes exist with MH physician offices (p < 0.05) and psychiatric hospitals' (p < 0.01) gross payroll. No statistically significant relationship exists between the Medicaid beneficiary rate and psychiatrist and psychologist employment. Conclusion: Medicaid provisions are related with the MH industry composition. An imbalanced MH industry may lead to inadequate management of MH disorders.
|
2022-08-24T07:03:00.893Z
|
86,303,138 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/pcmr.12135",
"MAG": "2128514109",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Our human ancestors who migrated out of Africa some 60 to 80 000 yrs ago and radiated across the globe were likely to have had a dark complexion, eye and hair colour, characteristics of African people today. As they encountered different climatic environments and selective pressures, novel gene variants in small founder groups increased in frequency when they conferred a selective advantage. Notably, many of the genes under selection were involved in human pigmentation (Sturm and Duffy, 2012), with some specific alleles reaching geographical or population-specific fixation, for example as discovered for the SLC45A2 Leu374Phe and SLC24A5 Ala111Thr gene polymorphisms in Europeans (Lamason et al., 2005). Using molecular techniques, the timing of these selective sweeps is proposed to have occurred some 11 to 19 000 yrs ago (Beleza et al., 2013), consistent with glacial melting and the movement of people into Northern Europe. Single-nucleotide changes (SNPs) with such high-frequency differences between population groups are often used as indicators of geographical ancestry, that is as ancestry informative markers (AIMs). The diversity of pigmentation is much greater between than within ancestral human populations, and identifying the genes responsible for these biological differences has long been of scientific interest. The most obvious contrast in phenotypes exists between black-white skin colour and brown-blue eye colour. The appearance of intermediate colours for these traits is especially apparent in offspring of parents from different biogeographical ancestries, providing an opportunity to understand the genes responsible, their inheritance and their mode of action. A unique population in which to address some of these issues is presented in the report by Beleza et al. The study population is located at Cape Verde, a group of 10 islands off the coast of West Africa first colonized by the Portuguese. Founder populations there have been established over several centuries, drawing from extensive admixture between African and European ancestral populations. These populations provide a wide spectrum of skin and eye colours and represent a resource to address two questions: to identify the contribution of specific gene polymorphisms to the range of colours seen in individuals, and to study the effect of genome-wide ancestry, an issue not suitable for genetic association studies conducted within homogeneous populations. There were 699 individuals included in the study whose genotypes were determined using a high-density array of over 1 9 10 SNPs. Skin phenotype was quantified by reflectance spectroscopy giving a measure of melanin content (MM, square root of the M-index), and eye colour was classified using a new algorithm based on digital photographs and RGB colour scale reflectance (T-index). This combination of genotypic and phenotypic information was analysed to detect and quantify the contribution of four loci to the range of human skin colours, SLC45A2, SLC24A5, TYR and OCA2[APBA2], and two to eye colour variation, OCA2[HERC2] and SLC24A5. Although these genes and even the population-specific polymorphisms were sometimes already known to contribute to the differences between African and European skin colour, estimates of the relative contributions of these genes and the polygenic background generally are of considerable interest. Surprisingly, other loci known to contribute to variation within European (MC1R) or between European and African (KITLG) skin colour were not detected. Blonde and red hair colours are reportedly rare in Cape Verde, consistent with the population founders from Europe being non-carriers of the alleles responsible for these traits (MC1R RHC alleles), which also overlap with skin colour. Why KITLG effects were not detected is less obvious, although one possibility is that its contribution may have simply been too small to detect in this population sample. The mean M-index value for Europeans was 5.38 (SD 0.27), while Cape Verdeans had a mean of 7.39 (SD 0.85). On this scale, the effect sizes of the alleles were SLC24A5 0.34, SLC45A2 and OCA2[APBA2] each 0.18, and TYR 0.2, with the sum of the effect sizes shifting only about 1/3 of the total range of skin colour observed. The population-attributable variance (PAV) is a novel index these authors present, which attempts to capture the extent of both intragametic and extragametic association between a given locus and a phenotype for a given admixed population. Like population-attributable fraction in epidemiology, it is non-additive. So, although the proportion of variance in skin colour within the Cape Verdean population explained by overall genomic ancestry was 44%, and approximately half of this was explainable by the SLC24A5, SLC45A2, OCA2[APBA2] and TYR gene, the PAVs were 18, 7, 9 and 7%, respectively, reflecting a combination of direct effect and the different efficiencies of these markers as proxies for overall ancestry. Their conclusion points to an underlying genetic architecture in this admixed population in which several genes of moderate effect, in this case four for skin and two for eye, act together with many other genes of small effect to explain around 70% of the estimated heritability of colour variation measured. A possible lesson for the forensic applications of this work in the prediction of pigmentation phenotype Coverage on: Beleza S, Johnson NA, Candille SI, Absher DM, Coram MA, Lopes J, Campos J, Ara ujo II, Anderson TM, Vilhj almsson BJ, Nordborg M, Correia E Silva A, Shriver MD, Rocha J, Barsh GS, Tang H. (2013). Genetic architecture of skin and eye colour in an African-European admixed population. PLoS Genet. 9(3):e1003372.
|
2022-09-12T02:37:22.202Z
|
191,792,737 |
{
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"DOI": "10.3917/ENTRE.173.0015",
"MAG": "2947237845",
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},
"license": null,
"status": null,
"url": null
}
|
Les hauts niveaux de satisfaction professionnelle rapportes par les proprietaires-dirigeants de PME sont des arguments pour soutenir leur capacite particuliere a faire face au stress au travail. La satisfaction serait explicative de la motivation, de l’engagement et de la resilience. Ces arguments reposent sur un effet moderateur exerce par la satisfaction sur les effets induits par les demandes professionnelles exigeantes. L’objectif de ce travail est d’examiner cet effet moderateur de la satisfaction professionnelle sur les effets induits par les tensions de roles sur l’epuisement emotionnel. L’analyse des donnees collectees (n = 280) permet de confirmer les effets negatifs induits par les tensions de roles et l’epuisement emotionnel sur la satisfaction professionnelle. Ainsi, ces resultats soutiennent le role premier d’une ressource. Toutefois, les autres resultats ne permettent pas de confirmer l’effet moderateur de la satisfaction sur la relation entre les tensions et l’epuisement. La difference entre salaries et proprietaires-dirigeants de PME ne serait pas dans le niveau de satisfaction, mais dans les relations qui la definissent. Les differents resultats concernant la satisfaction professionnelle et l’epuisement emotionnel sont discutes.
|
2022-10-28T01:05:59.261Z
|
134,253,147 |
{
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"ArXiv": null,
"DOI": "10.1175/JHM-D-17-0072.1",
"MAG": "2755309414",
"PubMedCentral": null
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"license": null,
"status": null,
"url": null
}
|
AbstractThe relationship between orographic precipitation, low-level thermodynamic stability, and the synoptic meteorology is explored for the Snowy Mountains of southeast Australia. A 21-yr dataset (May–October, 1995–2015) of upper-air soundings from an upwind site is used to define synoptic indicators and the low-level stability. A K-means clustering algorithm was employed to classify the daily meteorology into four synoptic classes. The initial classification, based only on six synoptic indicators, distinctly defines both the surface precipitation and the low-level stability by class. Consistent with theory, the wet classes are found to have weak low-level stability, and the dry classes have strong low-level stability. By including low-level stability as an additional input variable to the clustering method, statistically significant correlations were found between the precipitation and the low-level stability within each of the four classes. An examination of the joint PDF reveals a highly nonlinear r...
|
2022-09-16T09:47:16.078Z
|
31,034,403 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/INTLEC.2015.7572483",
"MAG": "2525900183",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper proposes Z-source with voltage multiplication inverter for grid connected Photovoltaic (PV) application. The proposed scheme has two-stage. The first stage consists of Z-source with voltage multiplication converter. The proposed converter has high gain compared to other transformer less topologies and reduced voltage stress on the switch. The second stage assembled from five switch inverter. The purpose of the first stage is to boost the low voltage of the PV module to a voltage level suitable for grid connection and controls the PV modules at Maximum Power Point (MPP). The second stage used to convert DC voltage into AC voltage and inject sinusoidal current with unity power factor into the grid. Model Predictive Control (MPC) is proposed to control the proposed system. MPC has some inherent advantages such as fast tracking, very small settling time and ease of implementation.
|
2022-09-29T23:33:38.170Z
|
30,229,831 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1103/PhysRevLett.116.225002",
"MAG": "2518252784",
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},
"license": null,
"status": null,
"url": null
}
|
Summary form only given. Photonic crystals are one- or multi-dimensional periodic structures with periodicity length of the order of an optical wavelength. Photonic band structures are analogues to electronic bands, also showing frequency bands (photonic bandgaps) of inhibited optical modes. Research work on solid state photonic crystals started several decades ago and developed into a wide field of applications, ranging from Bragg mirrors, dispersive elements to nonlinear structures in which light is controlled by light. Here we present a new type of transient photonic crystals for high-power lasers. The crystal is produced by counterpropagating laser beams in plasma. Trapped electrons and electrically forced ions generate a strong density grating, where the peak plasma density can be even in the overdense regime. The life-time of the transient photonic crystal is determined by ballistic motion of ions and on the time-scale of several ps. The robustness of the photonic crystal allows manipulation of high-intensity laser pulses. The scheme of the crystal is analyzed by 1D Vlasov simulations. Reflection or transmission of high-power laser pulses is predicted by particle in cell (PIC) simulations. It is shown that a transient plasma photonic crystal may act as a tunable mirror for laser pulses up intensities of 1017 W/cm2 and down to pulse durations of a few tens of fs. Generalizations to 2D and 3D configurations are possible, which open up the possibility for novel photonic structures in the context of ultra-high power laser radiation.
|
2022-12-19T05:47:59.257Z
|
24,665,325 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1074/jbc.273.4.2008",
"MAG": "2012585409",
"PubMedCentral": null
},
"license": "CCBY",
"status": "HYBRID",
"url": "http://www.jbc.org/article/S0021925819841509/pdf"
}
|
The preceding paper (Cha, H. H., Cram, E. J., Wang, E. C., Huang, A. J., Kasler, H. G., and Firestone, G. L. (1998) J. Biol. Chem. 273, 0000–0000(478563) defined a glucocorticoid responsive region within the promoter of the p21 CDK inhibitor gene that contains a putative DNA-binding site for the transcription factor CCAAT/enhancer binding protein-α (C/EBPα). Wild type rat BDS1 hepatoma cells as well as as4 hepatoma cells, which express antisense sequences to C/EBPα and ablate its protein production, were utilized to investigate the role of this transcription factor in the glucocorticoid regulation of p21 gene expression. The stimulation of p21 protein levels and promoter activity, as well as inhibition of CDK2-mediated retinoblastoma protein phosphorylation, by the synthetic glucocorticoid, dexamethasone, required the expression of C/EBPα. Overexpression of C/EBPα in as4 cells rescued the dexamethasone responsiveness of the p21 promoter. Site-directed mutagenesis of the p21 promoter revealed that dexamethasone stimulation of p21 promoter activity required the C/EBP consensus DNA-binding site. Furthermore, in glucocorticoid receptor-defective EDR1 hepatoma cells, dexamethasone failed to stimulate C/EBPα and p21 protein expression and promoter activities. Our results have established a functional link between the glucocorticoid receptor signaling pathway that mediates a G1 cell cycle arrest of rat hepatoma cells and the transcriptional control of p21 by a cascade that requires the steroid induction of C/EBPα gene expression.
|
2022-12-21T01:46:26.425Z
|
214,519,172 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.37398/jsr.2020.640142",
"MAG": "3005849621",
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},
"license": null,
"status": "BRONZE",
"url": "https://doi.org/10.37398/jsr.2020.640142"
}
|
207 DOI: http://dx.doi.org/10.37398/JSR.2020.640142 Abstract: An overview of the preparation, characterization and applications of coinage metal nanoparticles have been presented in this article. These nanoparticles exhibit a varieties of colors upon their interaction with UV-VIS light and are also known as nanoresonators. The color variation is found to be a function of shape, size and concentration of nanoparticles. A characteristic surface Plasmon resonance band at a particular wavelength is observed for a particular type of nanoresonators in the UV-VIS region. The real time chemosensing/biosensing through an appropriate type of nanoresonators is a burgeoning area since last couple of decades. A few representative cases of chemosensing/biochemosensing through nanoresonators derived from copper, silver and gold have been presented over here.
|
2022-02-08T02:30:15.296Z
|
111,237,744 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1049/IC:20070817",
"MAG": "2083871790",
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},
"license": null,
"status": null,
"url": null
}
|
This article consists of power point presentation on ArrayComm multiple antenna signal processing for WiMAX. It demonstrably confirmed the benefits of A-MAS, delivers substantial performance improvements, easy to integrate into a WiMAX BS architecture, Wave#2 compliant flexible solution and improves performance for all zones. Hardware-in-Loop is a valuable demonstration tool for realistic, demonstrative and versatile real performance measurement. It easily measure and investigate DSP implementation issues. (23 pages)
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2022-02-10T04:26:03.945Z
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249,727,860 |
{
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"DOI": "10.36074/grail-of-science.27.05.2022.065",
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"url": "https://archive.journal-grail.science/index.php/2710-3056/article/download/217/214"
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Відповідно до математичної моделі багатопроменевого каналу запропоновано імітатор, що дозволяє дослідити реальні іоносферні та тропосферні системи та моделювати спотворення радіосигналів при їх поширенні через траси великої протяжності.
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2022-07-09T03:07:02.085Z
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119,818,462 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1006/JMVA.1993.1006",
"MAG": "1991350909",
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"status": null,
"url": null
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Denoting by X(1) = 3 if and only if F is either a uniform distribution on an interval or a discrete uniform distribution supported on a set of equispaced points. The heart of our proof is the interesting observation that the above equation involving conditional expectations completely determines the (topological) structure of the support of the underlying distribution F.
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2022-09-14T15:02:41.779Z
|
207,622,743 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3171/2016.12.JNS16383",
"MAG": "2619473780",
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"status": null,
"url": null
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OBJECTIVE Subthalamic nucleus deep brain stimulation has been shown to be effective in reducing symptoms of primary Meige syndrome. However, assessments of its efficacy and safety have been limited to several case reports and small studies. METHODS The authors performed a retrospective study to assess the efficacy and safety of bilateral subthalamic nucleus stimulation in 15 patients with primary Meige syndrome who responded poorly to medical treatments or botulinum toxin injections. Using the movement and disability subscores of the Burke-Fahn-Marsden Dystonia Rating Scale, the authors evaluated the severity of patients' dystonia and related before surgery and at final follow-up during neurostimulation. The movement scale was assessed based on preoperative and postoperative video documentation by an independent rater who was unaware of each patient's neurostimulation status. Quality of life was assessed with the Medical Outcomes Study 36-Item Short-Form General Health Survey. RESULTS The dystonia movement subscores in 14 consecutive patients improved from 19.3 ± 7.6 (mean ± standard deviation) before surgery to 5.5 ± 4.5 at final follow-up (28.5 ± 16.5 months), with a mean improvement of 74% (p < 0.05). The disability subscore improved from 15.6 ± 4.9 before surgery to 6.1 ± 3.5 at final follow-up (p < 0.05). In addition, the postoperative SF-36 scores increased markedly over those at baseline. The authors also found that bilateral stimulation of the subthalamic nucleus immediately improved patient symptoms after stimulation and required lower stimulation parameters than those needed for pallidal deep brain stimulation for primary Meige syndrome. Four adverse events occurred in 3 patients; all of these events resolved without permanent sequelae. CONCLUSIONS These findings provide further evidence to support the long-term efficacy and safety of subthalamic nucleus stimulation as an alternative treatment for patients with medically intractable Meige syndrome.
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2022-11-28T17:42:18.511Z
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100,104,310 |
{
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"DOI": "10.1039/C6EN00570E",
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"status": null,
"url": null
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|
We have demonstrated the use of the inner lumen of halloysite nanotubes as a nanoconfined reactor for the synthesis of nanoscale inorganic materials. Selective modification of the lumen has been carried out using a chelating ligand like ethylenediaminetetraacetic acid (EDTA) which selectively binds only to the alumina surfaces of the tubes and thus facilitates the adsorption of iron and subsequently the formation of nanoscale iron oxide within the lumen of the clay nanotubes. Lumen modification followed by the formation of iron oxide in the clay nanotubes has been evidenced by several physical methods, authenticating the successful incorporation of EDTA as well as formation of α-Fe2O3 nanorods inside the lumen and finally producing α-Fe2O3/HNTs nanocomposites that exhibit solar light-induced enhanced photocatalytic activity. This study represents the first demonstration of the selective modification of the halloysite lumen using a chelating ligand to direct the in situ synthesis of iron oxide nanorods. Thus, the selective lumen modification under mild conditions to produce novel inorganic–organic hybrid nanocomposites may open up a new direction in the frontier area of nanoconfined reactions and hence may impart a broader impact in the field of catalysis, environmental remediation and even in drug delivery.
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2022-12-17T09:40:28.891Z
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32,506,519 |
{
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"ArXiv": null,
"DOI": "10.1039/c4dt03415e",
"MAG": "2065587818",
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"status": null,
"url": null
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Three new solvent-induced metal-organic frameworks (MOFs)-[Cd(H2L)(H2O)3]·NMP (), [Cd3(L)(H2O)4(OH)2] () and [Cd(L)0.5(H2O)]·H2O ()-were designed and successfully prepared via solvothermal reaction by multidentate phenyltetracarboxylic acid [1,1':4',1''-terphenyl]-2',3,3'',5'-tetracarboxylic acid (H4L) and Cd(ii) salts in various solvent systems. Structural analyses indicated that the H2L/L ligands took three different coordination fashions in , and thus resulted in diversity of the targeted MOFs. Solid-state luminescent properties of the three MOFs were studied under ultraviolet light irradiation at ambient temperature; in particular showed high selectivity and sensitivity for Cu(2+) ions and nitrobenzene because of the quenching effect, which thus could make it a potential crystalline material for detecting these substances. The mechanisms of the quenching effect and sensing properties of are discussed in detail.
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2022-12-18T22:24:26.624Z
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