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236,350,067 |
{
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"DOI": "10.4236/IJG.2021.125025",
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|
The crustal basement of Northwest Germany can be interpreted as an
“Avalonian Terrane Assemblage” subdivided by a roughly NW-SE (Hercynian) and
SW-NE (Rhenish) running horst and graben system. In Late Devonian and Early
Carboniferous times, this assemblage was flooded by the sea and mainly marine
carbonates were deposited on the horsts and Stillwater shales in the grabens,
as interpretable through magnetotelluric measurements. During the Late Carboniferous Variscan Orogeny, this
terrain became the coal-rich foreland
of the colliding Rhenohercynian belt. The shale-filled grabens reacted through folding and thrusting with different
anticlinal patterns, the main carbonate covered horst in a still unknown
way. This horst was the location of the Late Carboniferous basin center and of
the inverted oil-rich Mesozoic Lower Saxony Basin (southwestern sector),
respectively, with the so-called Bramsche Massif therein. It probably acted as
an indenter for the evolution of the Variscan ore-rich Harz Mountains and
forced the approaching Rhenohercynian orogen to stack the appropriate tectonic
nappes by horizontal shortening to very high altitudes and the root into large
depths. Based on seismic evidence this root is still an uncompleted
crust/mantle transition zone with a deep reflection seismic and petrological
Moho and a shallower hardly reflecting refraction seismic velocity Moho. The
alternative, partly unsolved location of the Variscan Deformation Front in
Northwest Germany may represent the new findings. The results may be supported
by a comparison with features of the northern Alpine deformation belt.
|
2022-12-14T04:31:31.589Z
|
129,113,414 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1144/GSL.JGS.1938.094.01-04.17",
"MAG": "2106731361",
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|
Research into the geology of New Zealand has shown the existence of rocks containing faunas of Silurian or Devonian age in not widely separated localities in the north of South Island. These faunas were named, after the localities, the Reefton and the Baton river faunas. The Reefton fauna has been studied in detail by Dr. R. S. Allan (1935), who proved conclusively that it was of Lower Devonian age with great similarity to the Upper Siegenian and Lower Emsian (= Lower Coblenzian) faunas of western Europe. The Baton river fauna is the subject of the present study. The collection upon which the work is based consists of three parts. First, the collections of the New Zealand Geological Survey under J. Hector from locality 128 (Baton river); second, the collections of a more recent survey; and third, a series of specimens from Auckland University College. The collections were brought to England by Dr. R. S. Allan, together with that from Reefton. He was unable to make a detailed study of the Baton river fossils, which he left with Professor O. T. Jones, at that time at the University of Manchester. With the consent of the Director of the New Zealand Geological Survey, Professor Jones asked me to take up the study of the fauna. The earliest detailed account of the stratigraphy of the Baton river and Wangapeka districts is by Mackay (1879, pp. 121–31). He mentions (pp. 125–6) that a large collection of fossils was made from the Baton river series
|
2022-12-16T10:23:36.415Z
|
53,317,772 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2139/ssrn.372161",
"MAG": "2038164255",
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},
"license": null,
"status": "GREEN",
"url": "https://archive-ouverte.unige.ch/unige:5794/ATTACHMENT01"
}
|
This paper investigates the relation between the term structure of rents and future spot rents. A rich database of office rental agreements for various maturities is used to estimate the term structure of rents, and from this structure implicit forward rents are extracted. The data pertain to commercial properties in the three largest Swedish cities for the period 1998-2002. A positive relation between forward and spot rents is found in some regions, but forward rents underestimate future rent levels. Another contribution of the paper lies in the area of rental index construction. We provide evidence that rental indices should not only be quality-constant (i.e. indices should not only control for the characteristics of rental units), but should also be maturity-constant.
|
2022-12-19T00:14:45.478Z
|
3,754,164 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.18632/oncotarget.13609",
"MAG": "2556334360",
"PubMedCentral": "5352055"
},
"license": "CCBY",
"status": "GOLD",
"url": "http://www.oncotarget.com/index.php?journal=oncotarget&page=article&op=download&path%5B%5D=13609&path%5B%5D=43227"
}
|
Cancer-associated fibroblasts (CAFs), a major component of cancer stroma, play an important role in cancer progression but little is known about how CAFs affect tumorigenesis and development. MicroRNAs (miRNAs) are small non-coding RNAs that can negatively regulate target mRNA expression at post-transcriptional levels. In head and neck cancer (HNC), our analysis of miRNA arrays showed that miR-7, miR-196 and miR-335 were significantly up-regulated in CAFs when compared with their paired normal fibroblasts (NFs). FAP, α-SMA and FSP, specific markers of CAFs, were significantly expressed in CAFs. Functionally, exogenous expression of miR-7 in NFs induced a functional conversion of NFs into CAFs. In contrast, inhibition of miR-7 expression in CAFs could induce a functional conversion of CAFs into NFs. Our study demonstrated that overexpression of miR-7 in NFs significantly increased the migration activity and growth rates of cancer cells in co-culture experiments. Mechanistically, we confirmed that the RASSF2-PAR-4 axis was mainly responsible for miR-7 functions in CAFs using bioinformatics methods. Overexpression of miR-7 in CAFs led to down-regulation of RASSF2, which dramatically decreased the secretion of PAR-4 from CAFs and then enhanced the proliferation and migration of the co-cultured cancer cells. Thus, these results reveal that the inactivation of the RASSF2-PAR-4 axis controlled by miR-7 may be a novel strategy for gene therapy in HNCs.
|
2022-12-27T16:16:43.595Z
|
44,458,607 |
{
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"ArXiv": null,
"DOI": "10.1074/JBC.M309434200",
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|
During early pregnancy, the steroid hormone progesterone induces differentiation of uterine stroma to decidual cells, which regulate embryo-uterine interactions. The progesterone-induced signaling molecules that participate in the formation and function of decidua remain poorly understood. We recently utilized high-density oligonucleotide microarrays to identify several genes whose expression is markedly altered in pregnant uterus in response to RU486, a well characterized antagonist of the progesterone receptor (PR). Our study revealed that the gene encoding cytotoxic T-lymphocyte antigen-2beta (CTLA-2beta), a cysteine protease inhibitor, is expressed during PR-induced decidualization. The spatio-temporal expression of CTLA-2beta mRNA precisely overlapped with the decidual phase of pregnancy. Interestingly, administration of progesterone to estrogen-primed ovariectomized mice failed to induce CTLA-2beta expression. A concomitant artificial decidual stimulation was necessary to trigger this expression. Uteri of PR knockout mice failed to express this mRNA, even after a combined administration of steroid hormones and artificial stimulation. The uterine expression of CTLA-2beta was, therefore, dependent on PR as well as other unknown factor(s) associated with decidual response. To identify the molecular target(s) of CTLA-2beta,we analyzed its interaction with proteins present in soluble extracts prepared from day 7 pregnant uteri containing implanted embryos. A protein affinity strategy employing recombinant CTLA-2beta helped us to determine that cathepsin L, a cysteine protease, is one of its targets in the pregnant uterus. Consistent with this finding, expression of cathepsin L was detected in the giant trophoblast cells of the ectoplacental cone on day 7 of pregnancy. Collectively, our results support the hypothesis that expression of CTLA-2beta in the decidua may regulate implantation of the embryo by neutralizing the activities of one or more proteases generated by the proliferating trophoblast.
|
2022-12-29T14:37:33.542Z
|
183,516,564 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1484/J.MS.2.306447",
"MAG": "2415351693",
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|
Un manuscrit complet du Livre de Margery Kempe fut decouvert en 1934. Ce manuscrit fournissait une chronique de sa vie dans le siecle et une description des symptomes de son etrange maladie. Si on diagnostique le syndrome de Tourette, cela permet de considerer Margery Kempe non pas comme une hysterique qui trouve une solution a ses conflits sexuels a travers des symptomes physiques, mais comme quelqu'un dont la pathologie influence l'attitude sociale, emotionnelle et physique. Elle tente d'integrer son mysticisme exuberant dans une devotion religieuse acceptable
|
2022-09-08T06:31:29.664Z
|
170,552,875 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1086/448918",
"MAG": "2071837428",
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"license": null,
"status": null,
"url": null
}
|
The invitation to participate in a small conference on Walter Benjamin at Yale's humanities center meant to assess the appearance of the first volume of Harvard's Selected Writings of Benjamin as a measure from which, as the letter of invitation frames things, nonspecialists in Benjamin studies are asked to "evaluate Benjamin's contribution to their respective fields," was irresistible, allowing one to speak from, without quite parading, an ignorance it is otherwise hard to overcome. Whatever the exact perimeter and surface of my field, let us say, of philosophy, judged by the work from which I have made a living for most of a lifetime, it is, and, while partially and restlessly, has wanted to be, territory shared with those who, however different otherwise, acknowledge some affinity with the later Wittgenstein and with J. L. Austin, ifjust so far as those thinkers are recognizable as inheritors, hence no doubt betrayers, of a tradition of philosophy that definitively includes Frege, Russell, Carnap, and Quine. Seen from that shared territory, an honest answer to the question of Benjamin's actual contribution to the field is that it is roughly nil. But if that were my sole space for an answer, I would not have accepted the prompting to respond to the question. Two helpful anthologies of writing about Benjamin-one from two or three years ago edited by Andrew Benjamin and Peter Osborne and one from ten years earlier edited by Gary Smith-are explicit in their wish to present Benjamin in his aspect, or should one say semblance, as a philosopher; both are explicit in wishing to counter the dominating semblance of Benjamin as a great critic, as lent to him in the English-
|
2022-09-14T12:49:56.196Z
|
4,684,172 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4236/JGIS.2012.42022",
"MAG": "1979149308",
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}
|
Advent of High Resolution Satellite Data (HRSD) with development of high spatial resolution sensors have revolutionized the generation of large scale maps. Generation of large scale digital utility maps using HRSD involves different methodologies and includes several steps wherein errors or spatial shift may be induced at any stage of data generation. It may be interesting to note that the characteristics of the spatial shift vary with methodologies adopted in its processing and has unique implications with respect to the data usage along with its application. Spatial shifts of points on a satellite data is result of unexpected translation and rotation of pixel with respect to the original location. Present study analyzes the spatial shift generated in satellite data with reference to the change in area and orientation of a group of pixels i.e. conformal and equal area properties of the rectified satellite data. This study aims to establish a relationship between the spatial resolutions of the satellite image used for digital map generation with the spatial accuracy achieved. In this study, Ground Control Points (GCP’s) identified on satellite data for a sample study area were validated using Differential Global Positioning System. Five different high resolution satellite images were analyzed to verify changes in area and shape with reference to the GCP’s. The results indicate that with improvement in the spatial resolution, higher precision in the digital maps is accomplished in terms of spatial shift of the points.
|
2022-10-14T00:28:03.399Z
|
57,880,330 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1001/JAMA.1967.03120150142052",
"MAG": "1967047276",
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"status": null,
"url": null
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|
The very name of Osler exerts a magic which brings back into focus a great physician and a great humanist. Outstanding among his medical achievements was his famous textbook. While very few presentday physicians want to read out-of-date textbooks, quite a few may want to dip into one written by Osier. For those who want to savor his medical experience, Appleton-Century-Crofts have reprinted selections from the seventh edition (1909), the last one which Osler wrote without collaboration. The editors have furnished a short introduction which provides some interesting information on the actual writing of the book and its subsequent course. The new volume reprints 17 chapters from Osler, including those on typhoid fever, pneumonia, rheumatic fever, diabetes mellitus, pernicious anemia, and angina pectoris. For each chapter the editors have selected a prominent specialist to write a short commentary. The book will probably receive highly favorable reviews in the medical journals,
|
2022-12-17T14:33:53.313Z
|
87,102,080 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.3161/00034541ANZ2016.66.1.009",
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"url": null
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|
Abstract. Paurodontella iranica sp. nov. is described and illustrated from West Azerbayjan province, Northwestern Iran. The new species was recovered from a soil sample from rhizosphere of Rosa persica Michx. ex Juss. It is characterized by body length of 681–1024 µm in females, lateral fields with four incisures; outer incisures crenate and inner smooth, stylet 8–9 µm long with asymmetrical knobs, excretory pore 100–140 µm far from anterior end, hemizonid 8–10 µm anterior to excretory pore, basal bulb with long stem-like extension projecting into the intestine, post-uterine sac rudimentary, tail short and sub-cylindrical. Mail tail conical with subterminal bursa. By having oviduct not branching to form a uterine diverticulum, the new species comes close to four known species of the genus namely P. densa (Thorne, 1941), P. balochistanica Handoo, Iqbal, Kazi et Fayyaz, 2010, P. niger (Thorne, 1941), P. asymmetrica (Tikyani et Khera, 1968). It resembles most closely P. balochistanica but differs from it by shorter stylet with asymmetrical knobs, more posteriorly located vulva and lateral field with four incisures. The sequence of D2-D3 expansion segments of 28S rDNA was provided for the new species. This is the first record of Paurodontella from Iran.
|
2022-12-17T22:25:43.495Z
|
62,764,874 |
{
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"ArXiv": null,
"DOI": "10.9717/KMMS.2014.17.8.977",
"MAG": "2028257501",
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"license": null,
"status": null,
"url": null
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|
Many of the recent performance evaluation of clustering schemes in wireless sensor networks considered one sink node operation and fixed sink node location without mentioning about any network application requirements. However, application environments have variable requirements about their networks. In addition, network performance is sufficiently influenced by different sink node location scenarios in multi-hop based network. We also know that sink location can influence to the sensor network performance evaluation because of changed multipath of sensor nodes and changed overload spots in multipath based wireless sensor network environment. Thus, the performance evaluation results are hard to trust because sensor network is easily changed their network connection through their routing algorithms. Therefore, we suggest that these schemes need to evaluate with different sink node location scenarios to show fair evaluation result. Under the results of that, network performance evaluation results are acknowledged by researchers. In this paper, we measured several clustering scheme’s performance variations in accordance with various types of sink node location scenarios. As a result, in the case of the clustering scheme that did not consider various types of sink location scenarios, fair evaluation cannot be expected.
|
2022-12-20T12:40:04.263Z
|
78,928,127 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1182/BLOOD.V114.22.1293.1293",
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|
Abstract 1293 Poster Board I-315 INTRODUCTION Type I von Willebrand disease (VWD) is the most common inherited bleeding disorder. Repetitive testing of von Willebrand factor (VWF) levels is necessary before the diagnosis can be safely ruled out, as VWF levels fluctuate in response to genetic and environmental factors. A predictive bleeding score (BS) could reveal individuals that may benefit from repetitive testing and those for whom repetitive testing is unlikely to be of benefit. While a standardized questionnaire (the Vicenza score) was developed to evaluate hemorrhagic symptoms, it was never prospectively validated for a pediatric population in a tertiary care setting. SUBJECTS The study targeted children, ages 0 to 17 years, referred to the Hemostasis and Thrombosis Center (HTC) of Nationwide Children9s Hospital for a coagulation evaluation as a result of bleeding symptoms, family history of a bleeding disorder and/or abnormal coagulation labs found during pre-operative screening. Children were excluded if they had a previously diagnosed bleeding disorder, if their caregiver did not speak English or if the child did not undergo VWF:Ag and VWF:RCo testing. METHODS Prior to the diagnosis or exclusion of a bleeding disorder in the child, caregivers consented to answer the questionnaire over the telephone. Descriptions of the Vicenza score are available online (http://www.euvwd.group.shef.ac.uk/bleed_score.htm). LABORATORY TESTING A single VWF:Ag or VWF:RCo RESULTS A total of 104 children (52 females and 52 males) with a mean age of 7.53 years (range 1 month to 17 years) were included. At least one hemorrhagic symptom was present in 99 of the 104 children (95%) with the mean number of symptoms being 2.87 (range 0 to 7). The mean Vicenza score was 3.24 (range -1 to 13). Of the 104 children, 8 met criteria for “Definite Type 1 VWD,” 23 met criteria for “Low VWF,” 14 were diagnosed with a “Platelet Function Defect,” and 2 children had bleeding secondary to Ehlers Danlos syndrome. Children with non-bleeding disorders (e.g. Factor XII deficiency) or no laboratory evidence of a bleeding disorder were classified as “No Bleeding Disorder.” In general, the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV) and positive diagnostic likelihood ratio of the bleeding questionnaire demonstrated poor predictive value in our patient population with the exception of high specificity in ruling out “Definite Type 1 VWD” (Table). The NPV was comparably high with both qualitative (>2 bleeding symptoms) and quantitative (BS ≥2) criteria. CONCLUSIONS The Vicenza score, previously validated in adults and in a pediatric primary care setting, appears to have limited predictive value in a pediatric tertiary care setting when evaluating patients with platelet function defects or low VWF levels. While the Vicenza score has a high NPV to exclude “Definite Type 1 VWD,” the use of simpler qualitative criteria is similarly predictive. Disclosures No relevant conflicts of interest to declare.
|
2022-12-20T15:40:29.202Z
|
97,336,925 |
{
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"DOI": "10.1111/J.1365-2621.2008.01876.X",
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|
Summary
This study was aimed to investigate the influence of solvent (water and ethanol in concentration: 50%, 70% and 96%) and extraction temperature (25–80) °C on polyphenols extraction of grape seed (Vitis vinifera L. cv. “Frankovka”) cultivated in Eastern Croatia. The best results were reached using 50% ethanol at 80 °C. The most abundant individual polyphenolic compound was catechin which makes the average of 45.11% of the total phenolic content followed by epicatechin (34.45%), procyanidin B2 (12.90%), gallic acid (5.34%), gallocatechin (1.58%), epicatechin gallate (1.01%). The antioxidant activity of extracts was determined by DPPH-method and it was highly dependent on extraction solvent and temperature. The total extractable proanthocyanidins content of extract had the highest positive correlation (r = 0.994) with antioxidant activity, which indicated that these compounds might be the most important antioxidant in examined grape seed extracts. Relationship between phenolic content and colour of extracts was observed.
|
2023-01-01T15:39:14.358Z
|
93,892,240 |
{
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"ArXiv": null,
"DOI": "10.1051/JP4:20030170",
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|
Generally, commercial finite element method (FEM) software was used for sheet forming simulation. In this study, anisotropic yield function for aluminum alloy sheets was investigated by using commercial FEM software LS-DYNA V950. Cup deep drawing test and punch stretching test simulation have been carried out using 5000 series aluminum alloy (4.5%Mg, l. Ommt) sheet. There was a little difference between forming limit of cup test simulation by using various yield functions. The forming limit and the state of principle strain near the fracture measured by experiment (using scribed circle method) was in good agreement with the results calculated by using Barlat model (1989). Barlat model would be suitable to sheet forming simulation for aluminum alloy because of its yield locus similar to aluminum alloys.
|
2022-02-10T16:41:43.587Z
|
246,626,780 |
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"DOI": "10.51542/ijscia.v3i1.8",
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"license": "CCBYNCND",
"status": "HYBRID",
"url": "https://www.ijscia.com/wp-content/uploads/2022/01/Volume3-Issue1-Jan-Feb-No.217-66-74.pdf"
}
|
The research objectives are to describe the effect of entrepreneurship training towards entrepreneurial interest, to describe the effect of work motivation towards entrepreneurial interest, and to describe the effect of entrepreneurship training and work motivation towards entrepreneurial interest. The business world needs strong young entrepreneurs, especially in the era of globalization, persistence skill, strong interest attitude in being able to compete in business world. Training or practice is alternative solution that can be chosen to build the mindset of young generation of Selimbau. Entrepreneurship is cultivated through the spirit of entrepreneurship, the ability to take risks, the ability to read opportunity. According to Kuratko (2018:5), Entrepreneurship must be done, tried, implemented because it is a dynamic process of vision, change and creation. Entrepreneurial interest arises from oneself or will not arise by itself suddenly from within the individual. Interest can grow or arise in a person through an external process or influence. The method used in this research is ex post facto of entrepreneurial training variables (16 items), work motivation (14 items) and entrepreneurial interest (15), with population of 51. The approach used is qualitative and multiple regression analysis.
|
2022-02-11T01:20:37.534Z
|
131,428,854 |
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"DOI": "10.5477/cis/reis.152.121",
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"license": "publisher-specific license",
"status": "GOLD",
"url": "https://doi.org/10.5477/cis/reis.152.121"
}
|
Beginning with the concept of globalism and the theory of the global system, the process of “industrial relocation of the Tangiers-Tetouan region (Morocco)” ...
|
2022-09-01T04:19:01.961Z
|
220,436,315 |
{
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"ArXiv": null,
"DOI": "10.1300/J229v01n01_09",
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|
Given the complexity of dissociative disorders, patients have been frequently misdiagnosed for a period up to 20 or more years. However, considerable progress has been made in the diagnosis, assessment, and treatment of dissociative disorders during the past decade, as reflected by increased clinical recognition of dissociative disorders, the publication of numerous scholarly works focusing on the subject, and the development of specialized diagnostic instruments. As there are at present no controlled outcome studies of different treatment regimens, future research, depending upon the use of new specialized clinical and research tools, will further add to our present understanding of the efficacy of the various therapies for the dissociative disorders. The guidelines attempt to summarize the numerous publications on the dissociative disorders, including case reports, open clinical trials, and investigations utilizing standardized tools. The guidelines
|
2022-09-05T21:34:41.161Z
|
147,436,960 |
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"DOI": "10.13169/WORLREVIPOLIECON.6.4.0544",
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|
1. IntroductionInternational Political Economy (IPE) emerged as a response to changes that the system underwent in the beginning of the 1970s. These changes were essentially perceived as a crisis of the American hegemony and the new forms of economic relations, represented by the rising multinational corporations and the renewed commercial and financial flows, which burgeoned on the liberalization and deregulation trend. Several theories were formulated in this new field of studies, both with "solving problem" and "critical" orientations, to use Cox's classification. In the first field, the theoretical elaboration began with the Hegemonic Stability Theory (HST) of Kindleberger and Gilpin and later progressed in the direction of the complex interdependence and the "liberal neoinstitutionalism" theories during the 1970s and 1980s. Interesting enough, HST, whose main concern was the preservation of American power and the liberal international capitalist order, was a decisive influence on at least one main theory of the "critical" camp, the World Systems (WS) perspective, especially in the way articulated by Giovanni Arrighi.The HST-WS link demonstrates one underlining association between the original IPE traditions formed in the 1970s: they were all focused on the problems that had an impact on the center of the world capitalist system, and specifically on the United States. In other words, they were two sides of the same debate. However, the conjuncture that was opened by the "crisis of the 1970s" was not only a system-core event, to use WS terminology, but had a decisive influence in the worlds periphery and on the debate about the "development" that raged in Latin America since soon after World War II, animated by the ideas formulated by United Nations Economic Commission on Latin America and the Caribbean (ECLAC, or in Spanish and Portuguese, CEPAL). In our view, this debate must be viewed as an IPE debate as well, since it involves the relation between power and wealth in the international arena. The wave of changes that began in 1970 affected the development debate through the impact that liberalization had on the dismantling of "Developmental States." This, together with the repressive tone that dominated "developmentalism" in its later stages, especially in Brazil, led to the formulation and dissemination of the dependency theories by the Marxists, as well as several attempts to reform the structuralist theory.Today, it is important to acknowledge the fact that virtually all the currents mentioned above, originated in the crisis of the 1970s, were severely contested by the events and trends that dominated the systemic conjuncture opened by that crisis. In that sense, HST and WS failed to account for the continuation of American power, the same problem that complex interdependence and neoliberal institutionalism faced. The latter still struggles with the additional failure of liberalization and international organizations to promote, even in moderated and tonedown forms, democracy, development, and equality throughout the world, as it had predicted. The same disconnection between theory, reality, and political projects and outcomes plagues the periphery perspectives originated during the 1970s and 1980s, which saw its hopes for socialist revolution or egalitarian and autonomous capitalist development systematically frustrated. Simultaneously with the crisis of the theoretical-political intellectual traditions of the IPE, which are part of a larger liberal-illuminist tradition of thought strongly informed by the notion of historical progress and modernity, we observe a strengthening of what was frequently classified, by that tradition, as pre-modern or dated phenomena, such as geopolitical competition, religious movements, and nationalism. This strengthens the need for a deep theoretical innovation, which goes beyond the classical illuminist paradigm, and its modern representatives, Marxism and liberalism. …
|
2022-09-11T07:29:13.739Z
|
240,648,797 |
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"DOI": "10.1103/physrevresearch.3.043023",
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"license": "CCBY",
"status": "GOLD",
"url": "http://link.aps.org/pdf/10.1103/PhysRevResearch.3.043023"
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|
We use numerical simulations to investigate the low-energy states of a bidisperse colloidal ice, realized by confining two types of magnetic particles into double wells of different lengths. For this system, theoretical calculations predict a highly degenerate ground state where all the vertices with zero topological charge have equal energy. When raising the applied field, we find a re-entrant transition where the system passes from the initial disordered state to a low-energy one and then back to disorder for large interaction strengths. The transition is due to the particle localization on top of the central hill of the double wells, as revealed from the position distributions. When we decrease the applied field, the system displays hysteresis in the fraction of low-energy vertices, and a small return point memory by cycling the applied field.
|
2022-09-15T09:44:44.214Z
|
123,471,592 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1142/S0217984906011037",
"MAG": "2082252024",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Trapping of hot electron behavior by trap centers located in the buffer layer of a wurtzite phase GaN MESFET has been simulated using an ensemble Monte Carlo simulation. The simulated results show that trap centers are responsible for current collapse in GaN MESFET at low temperatures. These electrical traps degrade the performance of the device at low temperatures. On the other hand, at high temperatures, the electrical performances are improved due to electron emission from the trap centers. The simulated device geometries and doping are matched to the nominal parameters described for the experimental structures as closely as possible, and the predicted drain current and other electrical characteristics for the simulated device including the trapping center effects show much closer agreement with the available experimental data than without trap center effects.
|
2022-09-23T23:59:52.382Z
|
213,980,991 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/acssuschemeng.9b05534",
"MAG": "2989853932",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A novel approach involving CO2 plasma treatment of intrinsic hydrogenated amorphous silicon was developed to form ultrathin silicon oxide (SiOx) layers, that is, passivated tunneling layers (PTLs), for the fabrication of passivated tunneling contacts. These contacts were formed by depositing the PTL/n-type hydrogenated nanocrystalline layer (nc-Si:H(n))/c-Si(n) stacks. The results indicated that a higher CO2 plasma treatment pressure was preferred for the formation of oxygen-richer components in the silicon oxide films, with Si2+, Si3+, and Si4+ peaks, and a smoother PTL/c-Si heterointerface. The PTLs with higher oxidation states and lower surface roughness exhibited advantages for the c-Si surface passivation, with a maximum implied open-circuit voltage of approximately 743 mV. The lowest contact resistivity of approximately 60 mΩ cm2 was obtained using nc-Si:H(n)/PTL/c-Si(n) as the passivated tunneling contact. Most importantly, the in situ process can help prevent the contamination of the heterointerfa...
|
2022-12-10T06:53:57.270Z
|
150,107,022 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/15363759.2017.1382399",
"MAG": "2884453209",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract This article focuses on the history of Christian higher education in China as a case study, building upon the work of scholars who have been seeking to better understand the identity and distinguishing marks of Christian higher education in a variety of settings worldwide. Although there had been 13 Christian colleges and universities in China before the Communist rule in 1949, such institutions had totally disappeared from China during the early 1950s, only to be revived to a limited extent three decades later due to a resurgence of the study of the history of Christian colleges in the 1980s. As one manifestation of the renewed interest in Christian higher education, in 2014 Yenching University Alumni Association celebrated the 95th anniversary of the founding of Yenching University in Beijing. This indication of interest reflects a new form of Christian presence in higher education in China that is quite different from elsewhere. In this article, the author describes some of the activities taking place over the past three decades in China that merit scholarly attention more broadly.
|
2022-12-17T22:24:36.888Z
|
41,932,095 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.13005/OJC/310138",
"MAG": "2074979585",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Dithiocarbamates are a class of metal-chelating compounds with various applications in medicine. They have been used for the treatment of bacterial and fungal infections, possible treatment of AIDS, and most recently cancer. Dithiocarbamates are well-known compounds to bind strongly and selectively to many metal ions.Dithiocarbamate ligands readily form chelates with metal ions through its two donor sulphur atoms.A new series ofplumbum(II) complexes with mixed ligands, dithiocarbamate, and 1,10-phenanthroline were successfully synthesised using in situ method. Microelemental analysis data of the complexes were in agreement with the general formula, Pb[S 2 CNR’R”] 3 phen (R’ = ethyl, R” = butyl, cyclohexyl; phen = 1,10-phenanthroline). Infrared spectra of the complexes showed that the thioureide (C-N) band was in the region 1450–1500 cm -1 . The unsplitting band of (C-S) in the region 930–1000 cm -1 indicated the bidentate nature of the chelated dithiocarbamato ligands. The 13C NMR chemical shift of the carbon atom of the N-CS 2 group appeared in the range of 202–207 ppm.
|
2022-12-23T02:12:24.169Z
|
5,634,015 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2183/PJAB.78.57",
"MAG": "2103330149",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
It was confirmed that nanometer-sized metal powder (atom clusters or simply clusters) can absorb an extremely large amount of deuterium/hydrogen atoms more than 300% against the number density of host metal. Within such clusters, the bonding potential widely changes from the center region to peripheral ones, so that the zig-zag atom-chains are always formed dynamically around the average position of atoms and the degree of filling up of the constituent atoms for the fcc type metal reduces to about 0.64 from 0.74 in bulk metal, i.e., vacant space increases to 0.36 from 0.26. As a result, a large amount of deuterium/hydrogen atoms are instantly dissolved into such host-clusters at room temperature. Furthermore, "metallic deuterium lattice" (or hydrogen one) including locally the "deuterium-lump" with the ultrahigh density is formed with body centered cuboctahedral structure which belongs to a unit cell of the host lattice, while such event cannot be realized at all within bulk metals. It seems that nuclear fusion in solid ("solid fusion") takes place in the highly condensed "deuterium-lump" inside each unit cell of the "metallic deuterium lattice" (or mixed hydrogen one) which is formed inside each cell of the host metal lattice. It is considered, therefore, that each unit cell of the host lattice corresponds to minimum units of "solid fusion reactor". In order to achieve "solid fusion", just the generation of the ultrahigh density "deuterium-lump" (simply "pycnodeuterium-lump") coagulated locally inside the unit cell of the host lattice and/or the highly condensed metallic deuterium lattice should be an indispensable condition.
|
2022-12-19T14:07:43.826Z
|
37,949,617 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1469-7580.2008.00948.x",
"MAG": "2149945132",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2732047"
}
|
Bone marrow stromal cells are multipotential cells that can be induced to differentiate into osteoblasts, chondrocytes, myocytes and adipocytes in different microenvironments. Recent studies revealed that bone marrow stromal cells could improve neurological deficits of various damages or diseases of the central nervous system such as Parkinson's disease, brain trauma, spinal cord injury and multiple sclerosis, and promote glia‐axonal remodeling in animal brain subjected to an experimentally induced stroke. In the present study, bone marrow stromal cells were intracerebrally transplanted into the cerebrum following a transient middle cerebral artery occlusion. Our aim was to find out whether the bone marrow stromal cells could survive and express neural phenotypic proteins and, in addition, whether they could restore the behavioral and functional deficits of the cerebral ischemic rats. Our results demonstrated that transplanted bone marrow stromal cells survived and migrated to areas around the lesion site. Some of them exhibited marker proteins of astrocytes and oligodendrocytes. Bone marrow stromal cell implantation significantly reduced the transient middle cerebral artery occlusion‐induced cortical loss and thinning of the white matter and enhanced cortical β‐III‐tubulin immunoreactivity. Rats implanted with bone marrow stromal cells showed significant improvement in their performance of elevated body swing test and forelimb footprint analysis and only transient recovery of the adhesive‐removal test. Our data support bone marrow stromal cells as a valuable source of autologous or allogenic donor cells for transplantation to improve the outcome following cerebral ischemia.
|
2022-12-20T20:04:52.913Z
|
58,551,004 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/acs.inorgchem.8b02877",
"MAG": "2910789324",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://pure.uva.nl/ws/files/47014695/acs.inorgchem.8b02877.pdf"
}
|
Iron catalyzed carbon-nitrogen bond formation reactions of a wide variety of nucleophiles and aryl halides using well-defined iron-complexes featuring redox noninnocent 2-(arylazo)-1,10-phenanthroline (L1) ligands are reported. Besides substrate centered C-N coupling, C-N bond formation reactions were also observed at the ortho- and para-positions of the phenyl ring of the coordinated azo-aromatic scaffolds affording new tetradentate ligands, 2-N-aryl-(2-arylazo)-1,10-phenanthroline (L2), and tridentate ligands, 4 -N-aryl-(2-arylazo)-1,10-phenanthroline (L3), respectively. Control experiments and mechanistic studies reveal that the complex [FeL1Cl2] (1) undergoes in situ reduction during the catalytic reaction to produce the monoanionic complex [1]-, which then acts as the active catalyst. The metal (iron) and the coordinated ligand were found to work in a cooperative manner during the transfer processes involved in the fundamental steps of the catalytic cycle. Detailed experimental and theoretical (DFT) studies were performed to get insight into the competitive substrate versus ligand centered amination reactions.
|
2022-12-26T05:12:56.537Z
|
931,721 |
{
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"ArXiv": null,
"DOI": "10.1111/2041-210X.12306",
"MAG": "2050104232",
"PubMedCentral": "4394709"
},
"license": null,
"status": null,
"url": null
}
|
‘Will my study answer my research question?’ is the most fundamental question a researcher can ask when designing a study, yet when phrased in statistical terms – ‘What is the power of my study?’ or ‘How precise will my parameter estimate be?’ – few researchers in ecology and evolution (EE) try to answer it, despite the detrimental consequences of performing under‐ or over‐powered research. We suggest that this reluctance is due in large part to the unsuitability of simple methods of power analysis (broadly defined as any attempt to quantify prospectively the ‘informativeness’ of a study) for the complex models commonly used in EE research. With the aim of encouraging the use of power analysis, we present simulation from generalized linear mixed models (GLMMs) as a flexible and accessible approach to power analysis that can account for random effects, overdispersion and diverse response distributions. We illustrate the benefits of simulation‐based power analysis in two research scenarios: estimating the precision of a survey to estimate tick burdens on grouse chicks and estimating the power of a trial to compare the efficacy of insecticide‐treated nets in malaria mosquito control. We provide a freely available R function, sim.glmm, for simulating from GLMMs. Analysis of simulated data revealed that the effects of accounting for realistic levels of random effects and overdispersion on power and precision estimates were substantial, with correspondingly severe implications for study design in the form of up to fivefold increases in sampling effort. We also show the utility of simulations for identifying scenarios where GLMM‐fitting methods can perform poorly. These results illustrate the inadequacy of standard analytical power analysis methods and the flexibility of simulation‐based power analysis for GLMMs. The wider use of these methods should contribute to improving the quality of study design in EE.
|
2022-12-31T18:12:51.271Z
|
28,982,125 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1055/s-0029-1237527",
"MAG": "2416982020",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Im Aufnahme-EKG der 80-jahrigen Patientin nach Anlage eines transvenosen passageren Herzschrittmachers in einem auswartigen Krankenhaus sind 2 Befunde erkennbar. WELCHE SIND DAS?ERLAUBEN DIESE BEFUNDE EINE DIAGNOSE? WENN JA, WELCHE?SIND DIFFERENZIALDIAGNOSEN MoGLICH? WENN JA, WELCHE?Auflosung
|
2022-02-12T13:56:15.543Z
|
248,690,853 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1742-6596/2255/1/012011",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://doi.org/10.1088/1742-6596/2255/1/012011"
}
|
We construct a simulation framework which can determine simultaneously deposited energy, position and time resolution of interactions of gamma rays in a monolithic scintillator crystal read out by a matrix of photosensitive detectors. And we report and discuss the simulation results form three different methods to determine the impact position of a particle.
|
2022-05-14T18:47:43.212Z
|
27,715,103 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/0020716031000103321",
"MAG": "2121257258",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
This paper investigates parallel predictor-corrector iteration schemes (PC iteration schemes) based on collocation Runge-Kutta corrector methods (RK corrector methods) with continuous output formulas for solving nonstiff initial-value problems (IVPs) for systems of first-order differential equations. The resulting parallel-iterated RK-type PC methods are also provided with continuous output formulas. The continuous numerical approximations are used for predicting the stage values in the PC iteration processes. In this way, we obtain parallel PC methods with continuous output formulas and high-accurate predictions. Applications of the resulting parallel PC methods to a few widely-used test problems reveal that these new parallel PC methods are much more efficient when compared with the parallel and sequential explicit RK methods from the literature.
|
2022-08-21T03:04:11.433Z
|
17,225,686 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/1467-8535.00253",
"MAG": "2073612872",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
During the last six months the British Educational Communications and Technology Agency (BECTa) has published two reports (downloadable from http://www.becta.org.uk/) on the relationship between information and communication technology (ICT) and attainment levels of primary school children in national tests. Together, they constitute a significant contribution to the debate over the place of ICT in our primary schools but they also raise a number of issues regarding the assumptions upon which they are based and the role of teaching staff in the successful exploitation of ICT in the classroom. This article provides a critical analysis of both reports and proposes ways in which the issues raised can be taken forward. Background BECTa’s first study, “Preliminary report for the DfEE on the relationship between ICT and primary school standards”, prompted many questions but offered few insights. Whilst it revealed a statistical correlation between ICT resources and levels of attainment at Key Stage 2, it did not attempt to identify any of the factors which might plausibly account for it. The second study builds on the findings of the first but attempts to make good this explanatory deficiency by looking for what it describes as the causal mechanisms linking the two phenomena. We need therefore to begin with a review of the first study which was based on two data sets drawn from Ofsted inspections carried out during the 1998‐99 school year: one centred on inspectors’ assessments of the adequacy of ICT provision and the other centred on Ofsted’s ranking of schools on the basis of their pupils’ scores in national tests at Key Stages 1 and 2. Both sets of data were compiled by Ofsted’s Research, Analysis and International Division and the sample as a whole consisted of the 2500 or so schools that were inspected in that year.
|
2022-11-04T20:28:58.559Z
|
249,676,423 |
{
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"ArXiv": null,
"DOI": "10.1097/01.cej.0000816644.52776.6e",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://journals.lww.com/eurjcancerprev/Fulltext/2021/12001/Prolonged_recombinant_pregnancy_hormone_use_for.3.aspx"
}
|
s S3 Abstracts of the meeting “40 Years of Science for the Future” for the 40 anniversary of the European Cancer Prevention (ECP) Organization, 16 October 2021, Hasselt, Belgiums of the meeting “40 Years of Science for the Future” for the 40 anniversary of the European Cancer Prevention (ECP) Organization, 16 October 2021, Hasselt, Belgium European Journal of Cancer Prevention 2022, 31:S1–S12 The birth of the European Cancer Prevention
|
2022-12-10T01:35:42.310Z
|
102,033,659 |
{
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"ArXiv": null,
"DOI": "10.13182/NT07-A3906",
"MAG": "2279072887",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper describes the uptake of plutonium, 238Pu, by an adsorbent consisting of Brimac 216 natural carbon, a type of bone char. A strongly magnetic Brimac 216 fine powder produced by Lidzey has been shown to be an excellent adsorbent for many radionuclides. After the adsorption of the radionuclides has taken place, from solution onto the magnetic Brimac 216 powder, the powder, together with the adsorbed radionuclides, can be rapidly removed from suspension, as a concentrate, using high gradient magnetic separation (HGMS). A comparison is drawn between experimental results using the conventional column filter, with bone char as the adsorbent medium, and calculations for the HGMS process to treat 3.22 m3 of solution containing 8 mg·l-1 of 238Pu and to remove the 238Pu from the suspension to reduce the effluent to less than the maximum concentration limit (MCL) for 238Pu, which is 0.74 Bq·l-1; however, the minimum concentration value used here is less than the MCL and is 0.0444 Bq·l-1 (7.006 · 10-14 g·l-1 of 238Pu) and is denoted as the lower concentration level. Calculations indicate that HGMS is considerably faster than the column filtration method. This leads to a significant reduction in the time required to process the solution, even though the HGMS process is repeated a number of times. Also, the mass of adsorbent requiring long-term storage is much smaller for HGMS than for the column filtration method.
|
2022-12-19T13:02:11.860Z
|
253,038,689 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/healthcare10102065",
"MAG": null,
"PubMedCentral": "9601658"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2227-9032/10/10/2065/pdf?version=1666080220"
}
|
Oral conditions, such as the number of teeth and oral hygiene, are related to oral functions and oral health-related quality of life (QoL) [...].
|
2022-12-18T05:17:36.782Z
|
20,209,307 |
{
"externalids": {
"ACL": null,
"ArXiv": "1603.07937",
"DOI": "10.3389/fams.2016.00007",
"MAG": "2307644894",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.frontiersin.org/articles/10.3389/fams.2016.00007/pdf"
}
|
For a system of coupled identical phase oscillators with full permutation symmetry, any broken symmetries in dynamical behaviour must come from spontaneous symmetry breaking, i.e. from the nonlinear dynamics of the system. The dynamics of phase differences for such a system depends only on the coupling (phase interaction) function $g(\varphi)$ and the number of oscillators $N$. This paper briefly reviews some results for such systems in the case of general coupling $g$ before exploring two cases in detail: (a) general two harmonic form: $g(\varphi)=q\sin(\varphi-\alpha)+r\sin(2\varphi-\beta)$ and $N$ small (b) the coupling $g$ is odd or even. We extend previously published bifurcation analyses to the general two harmonic case, and show for even $g$ that the dynamics of phase differences has a number of time-reversal symmetries. For the case of even $g$ with one harmonic it is known the system has $N-2$ constants of the motion. This is true for $N=4$ and any $g$, while for $N=4$ and more than two harmonics in $g$, we show the system must have fewer independent constants of the motion.
|
2022-12-18T11:25:37.639Z
|
46,402,019 |
{
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"ArXiv": null,
"DOI": "10.1002/glia.22629",
"MAG": "1815876215",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc4302754?pdf=render"
}
|
Network activity in the brain is associated with a transient increase in extracellular K+ concentration. The excess K+ is removed from the extracellular space by mechanisms proposed to involve Kir4.1‐mediated spatial buffering, the Na+/K+/2Cl− cotransporter 1 (NKCC1), and/or Na+/K+‐ATPase activity. Their individual contribution to [K+]o management has been of extended controversy. This study aimed, by several complementary approaches, to delineate the transport characteristics of Kir4.1, NKCC1, and Na+/K+‐ATPase and to resolve their involvement in clearance of extracellular K+ transients. Primary cultures of rat astrocytes displayed robust NKCC1 activity with [K+]o increases above basal levels. Increased [K+]o produced NKCC1‐mediated swelling of cultured astrocytes and NKCC1 could thereby potentially act as a mechanism of K+ clearance while concomitantly mediate the associated shrinkage of the extracellular space. In rat hippocampal slices, inhibition of NKCC1 failed to affect the rate of K+ removal from the extracellular space while Kir4.1 enacted its spatial buffering only during a local [K+]o increase. In contrast, inhibition of the different isoforms of Na+/K+‐ATPase reduced post‐stimulus clearance of K+ transients. The astrocyte‐characteristic α2β2 subunit composition of Na+/K+‐ATPase, when expressed in Xenopus oocytes, displayed a K+ affinity and voltage‐sensitivity that would render this subunit composition specifically geared for controlling [K+]o during neuronal activity. In rat hippocampal slices, simultaneous measurements of the extracellular space volume revealed that neither Kir4.1, NKCC1, nor Na+/K+‐ATPase accounted for the stimulus‐induced shrinkage of the extracellular space. Thus, NKCC1 plays no role in activity‐induced extracellular K+ recovery in native hippocampal tissue while Kir4.1 and Na+/K+‐ATPase serve temporally distinct roles. GLIA 2014;62:608–622
|
2023-01-01T17:49:01.499Z
|
145,023,825 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1104/pp.19.00326",
"MAG": "2942801534",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "http://www.plantphysiol.org/content/plantphysiol/180/1/14.full.pdf"
}
|
The endoplasmic reticulum (ER) has been likened to the manufacturing and packaging department of a factory, an action-packed production area that distributes things to the rest of the cell. The ER does this by forming complex networks of tubules and cisternae that connect to other membranous
|
2022-07-26T09:32:52.774Z
|
17,939,284 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CDC.1977.271589",
"MAG": "2002412574",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Our purpose in this paper is to highlight a few of the techniques and ideas that have found great utility in the design and analysis of Kalman filters. We focus attention on little discussed pragmatic aspects of filter design and details of computer implementation which are crucial for successful aircraft applications.
|
2022-09-10T14:46:01.071Z
|
12,102,575 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.15368/focus.2009v6n1.6",
"MAG": "138607855",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://digitalcommons.calpoly.edu/cgi/viewcontent.cgi?article=1138&context=focus"
}
|
In fall 2008 the City of Delano approached the City and Regional Planning Department through Department Head Bill Siembieda, expressing their wish for collaboration for Downtown Delano. Following a series of communications it was decided that a participatory effort for idea generation on the future of downtown would be appropriate for the task. A two-step timeline was developed with the Community Development Department of the City of Delano. As a first step, through Winter 2008, a Downtown Concept Plan was developed based on a community participation process with the residents of Delano. As the second step, in Spring 2008 quarter, CRP 203’s Section 02 developed three Urban Design Plan Proposals based on the Concept Plan developed earlier. In the following sections of this paper these two phases will be summarized.
|
2022-12-11T11:41:07.651Z
|
31,842,452 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/oxfordjournals.ndt.a091587",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "http://doc.rero.ch/record/291731/files/2-6-475.pdf"
}
|
This paper summarises the information given on the 1986 EDTA Registry centre questionnaire which was returned by 82% of the 2,065 known dialysis and transplant centres in 33 European countries. Information is given on the number of patients alive on haemodialysis according to the type of dialysis facilities available where the patient was receiving dialysis and the number of patients receiving special types of dialysis. The centre questionnaire also included questions on testing for HIV infection, serological evidence or symptoms of AIDS and the diagnosis of hepatitis B in patients and staff. The data given in response to these questions are presented together with data on the involvement of dietitians and social workers in the treatment of patients with end stage renal failure. Finally, information on transplant activity in Europe and the treatment policies of transplanting centres is provided.
|
2022-12-13T04:39:54.468Z
|
118,751,976 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1163/156939392X01552",
"MAG": "1509525504",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The theory of Lie algebras and their classification based on Dynkin diagrams is reviewed and application of the theory to vector wave scattering and propagation is outlined. The main applications arise through the matrix exponential function and associated matrix representations for the underlying groups. By projecting experimental measurements onto the eigenvectors of these basis elements, clear physical significance may be attached to the propagation operators. A new method for dealing with partially coherent propagators is outlined and an example for backscatter from a cloud of dipoles is used to illustrate the technique.
|
2022-12-15T04:59:15.649Z
|
218,040,712 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.7498/APS.64.244204",
"MAG": "3006291296",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
By using the truncated equations of the coupled wave, the expressions of the normalized electric field and the normalized intensity of the frequency doubling beam are derived in the cases with and without walk-off effect, caused by the off-axial vortex beam propagating through the negative uniaxial crystal. The influences of the off-axial magnitude, the weak walk-off angle and the crystal length on the output frequency doubling beam are mainly investigated. It is shown that while the walk-off angle is neglected, the two dark cores of the frequency doubling beam coincide with the point (0, 0); but while the weak walk-off angle is taken into account, the dark cores move along the direction where the walk-off effect is generated, and the two coincident dark cores separate in the direction perpendicular to the direction where the walk-off effect is generated on the cross-section. Especially, the distance the dark cores move is related to the off-axial magnitude, the weak walk-off angle and the crystal length. But the separation distance of the two dark cores is only related to the weak walk-off angle and the crystal length. The exact details show that when the off-axial magnitude increases, the distance the dark cores move along the direction where the off-axial magnitude is generated increases at the same time, but the separation distance has no connection with he off-axial magnitude. When the weak walk-off angle and the crystal length increase, the distance the dark cores move and the separation distance of the two dark cores increase. In addition, it can be found by comparison that when the crystal length reduces, the distance the dark cores move will decrease. And also the separation distance of the two dark cores will reduce, which is induced by the walk-off effect and the off-axial magnitude. Therefore, by reducing the crystal length, the output frequency doubling beam can be modified to a certain degree.
|
2022-01-27T09:47:08.232Z
|
5,370,911 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1001/JAMA.1996.03540180011004",
"MAG": "2091360958",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Shanghai, China WITH MORE than 40% of the world's cases of primary liver cancer, China is an appropriate site for international conferences on liver cancer. This year, Shanghai Medical University hosted the third Shanghai International Symposium on Liver Cancer and Hepatitis. The university has been holding these symposia every 5 years since 1986. More than 400 papers from around the world were presented at the conference, although the bulk were from researchers in China (Recent Progress in Liver Cancer and Hepatitis: Proceedings of 1996 Shanghai International Symposium on Liver Cancer and Hepatitis. Beijing, China: International Academic Publishers; 1996). Asked what was the most noticeable change between the second and third symposia, Sheng-Long Ye, MD, PhD, professor and vice chair of Shanghai Medical University's Liver Cancer Institute and coeditor of the symposium proceedings, said it was the dramatic increase of basic science that is now being applied to clinical research. Five
|
2022-02-13T10:55:57.551Z
|
11,957,876 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5772/20813",
"MAG": "1590186245",
"PubMedCentral": null
},
"license": "CCBY",
"status": "HYBRID",
"url": "https://www.intechopen.com/citation-pdf-url/22000"
}
|
1.1 Persistent Organic Pollutants (POPs) Persistent Organic Pollutants (POPs) is a common name of a group of pollutants that are semi-volatile, bioaccumulative, persistent and toxic. POPs comprising of pesticides, industrial chemicals and unintentionally produced POPs are toxic chemicals that adversely affect human health and the environment around the world (Vallack et al.,1998; Mocarelli &Tallman,1998 & Jones &de Voogt,1999). Since these pollutants can be transported by wind (natural ,human barriers and perturbation , grass in the desert ,cities and thermal updrafts, etc), water (ssurface, rain, ground, pumped and/or anthropogenically modified chemicals) and human intervention (waste-water conduits, drainage ditches, roadways, railways, irrigation, ponding, physical transformation physical collection and concentration, human species transformation) (Sw846,USEPA,2007) , most POPs generated in one country can affect people and wildlife far from where they are used and released. These chemicals persist for long periods of time in the environment and can accumulate and pass from one species to the next through the food chain. POPs can be deposited in marine and freshwater ecosystems through effluent releases, atmospheric deposition, runoff, and other means. As POPs have low water solubility, they bond strongly to particulate matter in aquatic sediments. As a result, sediments can serve as reservoirs or "sinks" for POPs. When sequestered in these sediments, POPs can be taken out of circulation for long periods of time. If disturbed, however, they can be reintroduced into the ecosystem and food chain, thereby potentially becoming a source of local, and even global contamination. To address this global concern, there exists a groundbreaking United Nations’ treaty in Stockholm, Sweden (May 2001). Under the treaty, known as the Stockholm Convention, countries agree to reduce or eliminate the production, use, and/or release of 12 key POPs (UNEP Tookits on POPs,1999,2001,2003,2005) which are shown in Table 1. The Convention specifies a scientific review process that could lead to the addition of other POPs chemicals of global concern. The list of nine new POPs added to the Stockholm Convention in May, 2009 is shown in Table 2.
|
2022-05-13T00:17:41.981Z
|
114,648,526 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3384/svt.1995.2.1.3026",
"MAG": "2593197167",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://socvet.se/article/download/3026/2350"
}
|
Den frivilliga sektorns roll i det sociala arbetet betonas allt mer i samhallsdebatten, det marks bland annat i socialtjanstkommittens nya betankande. Det tycks vara sa att frivilligsektorns roll ar under omprovning. I den har artikeln analyseras relationerna mellan det frivilligt organiserade sociala arbetet och staten . Med utgangspunkt i ett historiskt perspektiv diskuteras forutsattningarna for och konsekvenserna av att frivilligsektorn far en mer framtradande roll i produktionen av service pa det sociala faltet.
|
2022-09-08T23:26:32.857Z
|
147,034,886 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S000397561200032X",
"MAG": "2323265522",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
L ’ E M P I R E D E L A V A L E U R (The Empire of Value) aims to provide new foundations for economics. While this is certainly an ambitious task, the book’s author, Andr e Orl ean, is one of the best and most original economists working on the critique of, and the construction of an alternative to, mainstream economics. He is a leading proponent of the French approach known as the economics of conventions and is also closely connected with the r egulation school. His work reflects an unusual combination of characteristics: originally trained as an engineer at the prestigious École Polytechnique, Orl ean has both grasped the formal apparatus of modern economics and occasionally developed his own mathematical models; other heterodox economists have done the same, but Orl ean is particularly open to, and influenced by, contributions from other social sciences (authors such as Simmel, Simiand, Durkheim, and Girard are featured prominently in the book). As such, he has dialogued and collaborated with sociologists, anthropologists, historians, and many others. Readers who are already familiar with Orl ean’s work will note that L’Empire de la Valeur may be said to synthesize the main results of his research in the past decades, but it also elaborates on them and contains several new propositions. This is an excellent book that is profound, thought-provoking, erudite, rigorous, and relevant. The book is divided into three parts, respectively titled (1) ‘‘Critique of Economics’’, (2) ‘‘the Institution of Value’’, and (3) ‘‘Market Finance’’. The first part, containing three chapters, criticizes economics at a very fundamental level and is perhaps the one that many economists would find most controversial. Chapter I argues that both the utility theory of value and the labor theory of value share what he calls the ‘‘substantial hypothesis’’, namely, the idea that goods in markets have a substance – utility in the former theory, labor (or, more precisely, labor time) in the latter – that gives them value prior to exchanges and establishes the basis for their exchangeability. Orl ean forcefully rejects this idea. In his view, the only form for expressing value is the monetary one (p. 29). Barter, with which both variants of the substantial hypothesis are comfortable, cannot be considered the simplest expression of value; it is most often observed in non-market economies and is a sign of serious malfunctioning when observed in a market economy. (This argument is developed in the second part.) The chapter also points out problems and
|
2022-12-04T18:52:00.531Z
|
237,939,592 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/ijerph18189927",
"MAG": null,
"PubMedCentral": "8469117"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/1660-4601/18/18/9927/pdf?version=1632297934"
}
|
Of the 2.5 million people who are incarcerated in the United States, over half are parents. While it is well-established that incarceration has a detrimental impact on the children of incarcerated parents, less is known regarding the psychological impact of incarceration on parents themselves. The present review summarizes existing literature on the impact of incarceration on parents retrieved via online databases. Published articles were classified according to their overall themes and summarized. Pertinent studies include the psychological and emotional consequences of incarceration on parents, the experience of parenting while incarcerated, including barriers to parenting, the utility of parenting program interventions during periods of incarceration, and how these results differ for mothers and fathers. While the existing evidence introduces these issues, there is a need for additional research on the impact of incarceration on parents. These areas for future research as well as clinical implications are discussed.
|
2022-12-14T06:59:49.474Z
|
199,663,389 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5578/tt.67725",
"MAG": "2984417746",
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://doi.org/10.5578/tt.67725"
}
|
Introduction
The goals of chronic obstructive pulmonary disease (COPD) treatment are to relieve dyspnea, increase exercise capacity, and improve quality of life. The relation of exercise capacity, dyspnea level, and quality of life with long-term mortality is unclear. Aim of the study was to assess the effect of exercise capacity, dyspnea level and quality of life on long-term mortality risk in patients with COPD.
Materials and Methods
Dyspnea level was assessed using the modified Medical Research Council (mMRC), Borg and Baseline Dyspnea Index (BDI) and Body Obstruction Dyspnea Exercise (BODE), health-related quality of life with St. George's Respiratory Questionnaire, and exercise capacity with the 6-minute walking test (6MWT) and cardiopulmonary exercise test. At the end of 8-year follow-up period, the relation between these tests and mortality was examined.
Result
A total of 42 patients with stable COPD were included in the study. Sixteen patients died during the approximately 8-year follow-up period. Univariate analysis revealed that VO2 peak [HR: 1.845; CI: (1.336-2.55); p<0.001], BODE index [HR: 0.787; CI: (0.703-0.880); p<0.001], and SGRQ [HR: 1.073; CI: (1.028-1.119); p= 0.001] were significantly correlated to mortality risk. Multivariate Cox regression analysis revealed VO2 peak [HR: 1.031; CI: (0.683-1.120); p= 0.01] as the single significant predictor of mortality. VO2 peak less than 22.5 had a sensitivity of 82%, specificity of 80%, and area under the curve of 0.142 [95% CI: (0.027-0.257); p< 0.001] for mortality risk with ROC analysis.
Conclusions
Cardiopulmonary disturbances during maximal exercise may be an important indicator of mortality risk.
|
2022-06-26T09:03:21.937Z
|
208,360,565 |
{
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"DOI": "10.1177/096721099600400316",
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"url": null
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|
Colonic ischaemia after abdominal aortic grafting is a severe complication. Late detection of transmural ischaemia will result in a high mortality rate. No simple specific methods are available to detect the early stage. The aim of this pilot study was to detect and monitor sigmoidal ischaemia after aortic surgery with a new endoluminal sigmoidal probe, based on pulse oximetry. Twelve patients with sigmoidal ischaemia were included, the endoluminal probe being introduced into the sigmoid at least 25 cm proximal to the anal verge. It is shown that with this method mucosal and transmural ischaemia can be graded and differentiated. Patients who showed no wave-form had transmural ischaemia; those with mucosal ischaemia showed reliable wave-forms with oxygen saturation from 40–85%. Colonic ischaemia after aortic grafting can be detected bv endoluminal pulse oximetry but the clinical outcome will only improve by early detection in the preclinical stage. Copyright © 1996 The International Society for Cardiovasular Surgery.
|
2022-01-24T22:56:02.862Z
|
226,362,769 |
{
"externalids": {
"ACL": null,
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"DOI": "10.22271/chemi.2020.v8.i5ab.10606",
"MAG": "3093682238",
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://www.chemijournal.com/archives/2020/vol8issue5/PartAB/8-5-346-511.pdf"
}
|
Study was conducted to investigate pollen viability of four mango varieties, viz. Kesar, Alphonso, Mallika and Dudhpendo up to 56 days. Pollen grains were suspended in three different media (n-hexane, paraffin oil and without media) under four different storage temperature (-20 0C, -4 0C, 4 0C and room temperature). Aceto-carmine test was used to determine pollen viability. Variation due to different varieties, media, temperature and their interactions was found significant. Among four varieties, maximum viability was recorded in Kesar during 7, 14, 21, 49 and 56 days of storage, whereas, in Mallika, at 28, 35 and 42 days. In storage media, n-hexane was found best in terms of retaining viability. The storage at -20 0C gave better results in terms of viability in all four varieties. On the basis of results, it could be concluded that pollen grains of Kesar and Mallika could be stored successfully up to 56 days in n-hexane at -20 0C.
|
2022-01-27T02:52:32.860Z
|
239,421,794 |
{
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"DOI": "10.12681/eadd/44780",
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},
"license": null,
"status": null,
"url": null
}
|
Η διδακτορική διατριβή εξετάζει την ερυθρόμορφη παραγωγή του Nικοσθένη και του Παμφαίου, δύο κεραμέων του αττικού Κεραμεικού των αρχαϊκών χρόνων. Βασικό πυρήνα της εργασίας αποτέλεσαν τα υπογεγραμμένα αγγεία τους, δέκα του Νικοσθένη και σαράντα πέντε του Παμφαίου. Εξετάστηκαν καταρχάς τα σχήματα των αγγείων που κατασκευάστηκαν στα εργαστήριά τους με τη βοήθεια δημοσιευμένων τομών, αλλά και μέσα από πρωτότυπα σχέδια που παράχθηκαν στα μουσεία από τη συγγραφέα. Σε αυτά περιελήφθησαν εκτός των υπογεγραμμένων και ανυπόγραφα αγγεία που βάσει των λεπτομερειών του σχήματος αποδόθηκαν σε κάποιο από τα εργαστήρια. Το μεγαλύτερο μέρος της εργασίας είναι αφιερωμένο στους αγγειογράφους που εργάστηκαν για τους δύο κεραμείς, τόσο εκείνους που διακόσμησαν αγγεία με τις υπογραφές των κεραμέων, όσο και στους αγγειογράφους των ανυπόγραφων. H ενδελεχής εξέταση του στυλ τους οδήγησε σε κάποιες περιπτώσεις σε νέες αποδόσεις ή αποσυσχετισμούς έργων που τους είχαν κατά καιρούς αποδοθεί. Με ενδελέχεια εξετάστηκαν και τα εικονογραφικά θέματα που τους απασχόλησαν. Στην εργασία εξετάζονται και επιμέρους θέματα, όπως οι επιγραφές στα αγγεία και οι τόποι εύρεσής τους, ενώ γίνεται προσπάθεια για τον προσδιορισμό απόλυτων χρονολογικών ορίων για την έναρξη και παύση της παραγωγής των δύο εργαστηρίων.
|
2022-02-07T20:19:45.472Z
|
40,953,395 |
{
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"DOI": "10.1177/0890334416639575",
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|
3. The authors concluded that the suck-swallowbreathe process is highly variable during breastfeeding because: a. Milk removal is higher during nutritive sucking than nonnutritive sucking. b. Anatomical anomalies may contribute to reduced tongue mobility. c. The infant is able to control compression of the nipple and subsequent milk flow. d. The infant is able to rapidly adapt to changing milk flow rates during milk ejection.
|
2022-07-01T05:40:02.016Z
|
216,541,282 |
{
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"ArXiv": null,
"DOI": "10.15578/jksekp.v9i2.7764",
"MAG": "3015924135",
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},
"license": null,
"status": "GOLD",
"url": "http://ejournal-balitbang.kkp.go.id/index.php/jkse/article/download/7764/6428"
}
|
Budi daya lele merupakan komponen penting dalam sektor usaha perikanan air tawar di Kabupaten Tangerang dengan kontribusi lebih dari 70% (senilai Rp109,5 milyar) pada tahun 2018. Meskipun demikian, diperlukan peningkatan produksi di masa yang akan datang dalam rangka mengantisipasi perkembangan dan kebutuhan pasar. Peningkatan tersebut perlu didukung oleh informasi potensi budi daya serta strategi pengembangannya. Penelitian ini bertujuan untuk mendapatkan informasi mengenai karakteristik kegiatan budi daya serta merumuskan strategi pengembangan budi daya lele di Kabupaten Tangerang. Pengambilan data dilakukan melalui survei dengan kuesioner terstruktur selama bulan Oktober 2018 hingga Januari 2019. Metode analisis data terdiri atas analisis deskriptif dan analisis SWOT. Alternatif strategi yang diprioritaskan berdasarkan hasil analisis SWOT yaitu strategi SO (Strength-Opportunities) yang berada pada kuadran I. Peningkatan keterampilan, ketersediaan benih berkualitas, dan penerapan teknolologi informasi diharapkan mampu mendukung efisiensi, produktivitas dan keberlanjutan usaha. Alternatif strategi yang disarankan yaitu: (1) Dinas terkait memfasilitasi pelatihan teknologi intensifikasi budi daya yang ramah lingkungan, serta penyediaan benih unggul; dan (2) Perluasan wilayah pemasaran dan pengembangan usaha dengan memanfaatkan teknologi informasi, serta penguatan kerjasama antar pembudidaya. Title: Evaluation of Catfish Farming System: Production Aspect and Developmental Strategy, (Case studies: Catfish Farmers in Tangerang Regency) Catfish farming is an important element in the freshwater fisheries business in Tangerang Regency that contributes more than 70 percent of total production (Rp. 109.5 billion) in 2018. However, it is necessary to increase the number of future production to anticipate the market demand. This increasing production should be supported with information on potential aquaculture and its development strategies. This study aims to describe the characteristics of aquaculture activities as well as to formulate the development strategies of catfish farming in Tangerang Regency. Data were collected by structured questionnaires from October 2018 to January 2019. Data were analyzed using descriptive and SWOT analysis. Result of SWOT analysis suggests that SO (Strength-Opportunities), which was in quadrant 1, should be prioritized. Skill improvement, availability of good fingerling, and application of information technology were expected to encourage its productivity, efficiency, and business sustainability. The study suggests following recommendation: (1) Associated agencies facilitate training of green intensification on aquaculture technology and supply superior fingerlings; and (2) Market expansion and business development using information technology, and the intense cooperation among farmers.
|
2022-07-29T21:01:00.984Z
|
39,966,895 |
{
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"ArXiv": null,
"DOI": "10.1080/13803390600864760",
"MAG": "2049774425",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The Rey Auditory Verbal Learning Test (RAVLT) and the Brief Visuospatial Memory Test–Revised (BVMT-R) are frequently used in assessing dementia. Though sex differences in verbal learning and memory have been reported, normative data for the elderly often do not separate males and females. No studies provide normative data for both the RAVLT and the BVMT-R in the same elderly sample. Finally, normative data for those over age 79 are unavailable for the BVMT-R. Therefore, the purpose of this study was to evaluate sex differences on these two tests, provide normative data in 172 healthy volunteers between the ages of 60 and 89 (inclusive), and extend the age range of BVMT-R normative data. Females consistently outperformed males. However, only performance on the RAVLT warranted separation of normative data by sex. Age and sex differences as well as usage of these normative data in a clinical setting are discussed.
|
2022-12-16T11:19:14.073Z
|
81,644,478 |
{
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"ArXiv": null,
"DOI": "10.31274/RTD-180813-10747",
"MAG": "30788718",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Phospholipid (PL) fatty acid composition and stereospecific distribution of 25 genetically modified soybean lines having a wide range of compositions were determined by gas chromatography and phospholipase Aj hydrolysis. PL contained an average of 55.3% phosphatidylcholine, 26.3% phosphatidylethanolamine and 18.4% phosphatidylinositol, PL class proportions were affected by changes in overall fatty acid composition. PL fatty acid composition changed with oil fatty acid modification, especially for palmitate, stearate and linolenate. Stereospecific analysis showed that saturated fatty acids were primarily located at the sn-1 position of all PLs, and changes of the saturates in PLs were largely reflected on this position. Oleate was distributed relatively equally between the sn-1 and sn-2 positions. Linoleate was much more concentrated on sn-2 than on sn-1 position for all PLs. Linolenate was distributed relatively equally at low concentration but preferred the sn-2 position at high concentration. ' Reprinted with permission from J. Am. Oil Chem. Soc. 74(12);1587-1594 (1997), copyright© 1997. ^ Department of Food Science and Human Nutrition and the Center for Crops Utilization Research. ^ Author for correspondence. ^ Department of Agronomy.
|
2022-12-16T15:21:03.560Z
|
46,749,210 |
{
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"ArXiv": null,
"DOI": "10.1159/000168747",
"MAG": "1978282269",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The progress in science made by Henle depended on the improvements in light microscopy achieved in the 19th century. The advent of achromatic lenses in particular made it possible for Henle and his contemporary and friend Schwann to uncover the typical structures of cells, thus bringing order at the microscopic level to the world of living tissues. Henle's 'comprehensive' approach--4 basic types of tissue: epithelial, connective, muscular and nervous, contrasted with the accepted doctrine of Bichat of 21 different types of tissues that enter into different combinations in forming the organs of the body--together with rapid progress in chemistry and physics permitted the subsequent intimate probing of cellular physiology. Henle's work was not confined to the description of anatomic structures. After he had observed microorganisms in the excretions of diseased animals, he embraced the unpopular theory of 'contagion' as the source of infection, though he himself was not able to prove that microorganisms were the direct cause of diseases. His discovery of the renal tubule that now bears his name came comparatively late in his career, and although he described its structure in detail he offered no suggestions as to its function.
|
2022-12-20T03:22:26.991Z
|
15,305,022 |
{
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"ArXiv": null,
"DOI": "10.1109/CISIS.2015.82",
"MAG": "1599065239",
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},
"license": null,
"status": null,
"url": null
}
|
In previous work, we proposed a Message Suppression (MS) method for Vehicular Delay Tolerant Networking (Vehicular-DTN) considering Epidemic routing protocol. In this paper, we evaluate our proposed MS method considering three different DTN routing protocols under highly stressed environment. In order to evaluate the performance of MS method, we use Direct Delivery, Spray and Wait and Epidemic as DTN routing protocols. The simulations for two scenarios are conducted considering obstacles (buildings), where MS with Road side units (MSRs) are present and not present. We consider 802.11p standard and send bundle messages in a Manhattan grid scenario. We use the packet delivery ratio, end-to-end delay, number of replicated messages and storage usage as evaluation metrics. Based on simulation results, we found that our proposed method with Epidemic routing has better performance compared with other DTN routing protocols.
|
2022-12-19T17:31:22.394Z
|
14,629,237 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/AJPA.1330300107",
"MAG": "2095547583",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
During the rapid growth of a population from a few founders, a single deleterious gene in a founder can attain an appreciable frequency in later generations. A computer simulation, which has the population double itself in early generations, indicates a lethal could attain a frequency of 0.1. Since deleterious recessive genes are eliminated from large populations at a very slow rate, variations in their frequencies in present major human populations may be due to the founder effect during earlier rapid expansion.
|
2022-12-23T02:06:23.044Z
|
155,707,038 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/00128775.2000.11648735",
"MAG": "2202302153",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Pareto efficiency assumes that no individual can be made better off without causing another individual to be worse off. From the perspective of maximum efficiency, therefore, income transfers do not resolve problems of social welfare; rather, they lead to an overall loss in well-being. Nevertheless, for a number of reasons dealt with in theories of welfare, transfers are a component of social and economic policy: prominent among the reasons for this are the inequality of individuals and certain externalities.1 A generally accepted argument is also the mutual dependence of individuals in society. Some even argue that differentials in wages in society constitutes a public good (cf. the discussion in Barr 1994). In the trade-off between efficiency and equality, the most important factors are, on the one hand, the relative importance that society attributes to conflicting criteria, and, on the other hand, practical, political considerations regarding the consequences of the social tension caused by inequality. Second, an optimal division of goods among individuals or groups can be determined by the marginal utility of goods (incomes) for individuals or groups
|
2022-02-09T01:10:05.087Z
|
60,595,772 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1889/JSID19.2.212",
"MAG": "1965397733",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract— The exoemission of electrons from the MgO cathode surface has a great impact on many properties of plasma displays and needs to be carefully engineered for successful display products. A method for direct measurement of this exoemission current using an ultra‐high‐impedance amplifier, which detects the integrated exoemission charge collected by a capacitance, is presented. The large discharge and displacement currents initiated by the changing sustain waveform, which could overload and saturate the sensitive amplifier, are shorted by a very low impedance switch in the form of a common reed relay. The exoemission current from the MgO cathode is significantly amplified by avalanches in the gas, and thus methods for directly measuring the avalanche amplification factor so as to correct the measured current and obtain the true exoemission current from the cathode are described. This highly variable avalanche amplification factor is measured and estimated to be as large as 500 when the voltage across the gas is just below breakdown. Methods are covered to correct for the small ion currents that flow in the plasma‐panel soda glass substrates and that add an unwanted error signal. Practical circuit techniques for measuring the very small exoemission currents are presented.
|
2022-03-29T04:38:10.926Z
|
27,544,833 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1097/00005344-199100181-00010",
"MAG": "1981512500",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://journals.lww.com/cardiovascularpharm/Abstract/1991/06181/Nitrendipine_Efficacy_and_Safety_in_Patients_with.10.aspx"
}
|
The antihypertensive effect of nitrendipine was examined in 29 outpatients with a mild or moderate hypertension and type II diabetes or a dyslipidemic condition. The drug was administered for 90 days at a daily dose of 10 to 40 mg. Following a washout period, the blood pressure (measured by a Dinamap device) was 181/99 mm Hg supine and 172/104 mm Hg standing. Nitrendipine caused a reduction in both pressures and after 90 days their values were 148/74 and 143/80 mm Hg, respectively. Heart rate was not affected by the drug, which also caused no variation in blood pressure, total and HDL cholesterol, and triglycerides. In more than 20% of the cases, treatment was associated with headache and flushing, which did not necessitate discontinuation of treatment. Thus, nitrendipine is an effective antihypertensive agent and causes no untoward metabolic effects.
|
2022-07-04T21:17:05.111Z
|
228,956,892 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.37033/fjc.v5i2.209",
"MAG": "3095563252",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://indochembull.com/index.php/fulerene/article/download/209/91"
}
|
Minyak jelantah mengandung berbagai pengotor yang dapat menyebabkan berbagai masalah kesehatan dan lingkungan. Pada penelitian ini dilakukan pemurnian minyak jelantah untuk menurunkan kadar asam lemak bebas dan bilangan peroksida dengan menggunakan adsorben berbasis cangkang telur ayam (CTA) pada berbagai variasi temperatur kalsinasi. Proses persiapan adsorben dilakukan dengan menggunakan furnace elektrik selama 2 jam pada suhu 200, 400, 600 dan 800oC. Proses adsorpsi dilakukan selama 1 jam dengan pengadukan. Analisis yang dilakukan pada penelitian ini adalah analisis kualitas adsorben dan karakterisasi gugus fungsi dengan menggunakan FTIR (Fourier-transform infrared spectroscopy). Analisis kadar asam lemak bebas dan bilangan peroksida dilakukan dengan metode titrasi. Hasil penelitian menunjukkan bahwa adsorben CTA pada suhu kalsinasi 800oC (AE800) memberikan kualitas adsorben terbaik. Hasil karakterisasi menggunakan FTIR menunjukkan adanya puncak baru pada bilangan gelombang 3640 cm-1. Hasil pengukuran kadar asam lemak bebas dan bilangan peroksida adsorben AE800 mencapai 54,74% dan 65,79%. Hasil penelitian ini menunjukkan bahwa temperatur kalsinasi sangat mempengaruhi karakteristik adsorben dan CTA memiliki potensi untuk dikembangkan sebagai adsorben untuk meningkatkan kualitas minyak jelantah dan bahan baku pembuatan katalis berbasis CaO.
|
2022-08-20T08:47:22.049Z
|
193,577,191 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1162/LMJ_A_00965",
"MAG": "2522736650",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
ABSTRACT This article considers the distributed role that listening plays for both performer and audience in the process of discovering musical meaning in the context of electroacoustic improvisation through examination of particular emergent practices.
|
2022-08-29T09:23:07.679Z
|
144,023,677 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1163/157181195X00075",
"MAG": "2001944840",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This article examines the situation of the Russian minority in Estonia, focusing on legal issues. It traces back the historical reasons for the current minority problem which can be found in the demographic changes that took place after the country's annexation by the Soviet Union. The author examines the Estonian laws most relevant to the minorities and their compliance with international human rights standards. He sees the cardinal point from a legal perspective in the fact that international law basically does not restrict the sovereign right of a state to regulate its citizenship. Thus the author comes to the conclusion that Estonian laws in general do not violate international law. He points out that it would be false to reduce the problem to this legal issue and shows how the involvement of international organizations helped to mitigate a situation that could potentially lead to a violent confrontation.
|
2022-09-05T02:27:26.421Z
|
118,126,518 |
{
"externalids": {
"ACL": null,
"ArXiv": "quant-ph/0107116",
"DOI": "10.1142/S0217751X02009898",
"MAG": "1489826029",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We argue here that, just as it happens in classical and quantum mechanics, where it has been proven that alternative Hamiltonian descriptions can be compatible with a given set of equations of motion, the same holds true in the realm of statistical mechanics, i.e. that alternative Hamiltonian descriptions do lead to the same thermodynamical description of any physical system.
|
2022-09-19T05:06:29.020Z
|
209,360,406 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/1077546316647645",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://journals.sagepub.com/doi/pdf/10.1177/1077546316647645"
}
|
Abdon Atangana Exact solution of the time-fractional groundwater flow equation within a leaky aquifer equation. Journal of Vibration and Control 2016, Vol. 22(7) 1749–1756 DOI: 10.1177/1077546314544514 Nemat Nyamoradi and Yong Zhou Bifurcation results for a class of fractional Hamiltonian systems with Liouville–Weyl fractional derivatives Journal of Vibration and Control 2016, Vol. 22(5) 1358–1368 DOI: 10.1177/1077546314535827 These two articles were inadvertently published early. They were intended for publication in the Special Issue “Advances in Fractional Dynamics and Control Theory”, Journal of Vibration and Control, edited by Clara Ionescu, Yong Zhou and J. A. Tenreiro Machado, Volume 22 No. 8, published in May 2016, where they are reprinted for the convenience of print readers only.
|
2022-11-04T00:14:17.849Z
|
209,413,758 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.12688/f1000research.19909.1",
"MAG": "2995668137",
"PubMedCentral": "6913206"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://f1000research.com/articles/8-2092/v1/pdf"
}
|
Pyoderma Gangrenosum (PG) is a rare neutrophilic dermatosis with multiple different clinical presentations and associated comorbidities. PG has historically been a challenging disorder to diagnose, leading to the development of new diagnostic criteria rather than the traditional approach of a diagnosis of exclusion. The pathophysiology is thought to involve both innate and adaptive immune system dysregulation, neutrophilic abnormalities, environmental, and genetic factors. As of today, no gold standard therapy exists for the treatment of PG, and the literature is restricted to mainly case reports, case series, and 2 small randomized clinical trials. Topical, systemic, and biologic therapy, as well as adequate analgesia and proper wound care all play a role in the management of PG. Recent studies have identified additional cytokines and signalling cascades thought to be involved in the pathogenesis of PG, ultimately leading to the development of new targeted therapies. This review will focus on recent advances in the pathophysiology, clinical presentation and associated comorbidities, diagnosis, and management of PG.
|
2022-12-02T05:09:56.533Z
|
158,160,179 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.25115/EEA.V36I1.2520",
"MAG": "2796018417",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
La importancia de construir paridades subnacionales de poder adquisitivo (PPP) ha sido reconocida en la literatura por más de dos décadas. En países caracterizados por grandes diferencias territoriales en precios, calidad de productos y características del hogar, el cálculo de PPPs subnacionales puede mejorar la compilación regular de indicadores de tan gran importancia como los índices espaciales, el gasto real per cápita ajustado por diferencias de nivel de precios regionales y las estimaciones de desigualdad y la pobreza a escala nacional; también puede servir de insumo para estos agregados macroeconómicos. Este artículo proporciona una visión general de los requisitos en cuanto a datos y métodos de construcción de números índice diseñados específicamente para producir un conjunto coherente de comparaciones espaciales de precios; y una revisión de los intentos de compilación de PPPs subnacionales que se han llevado a cabo en todo el mundo. En especial, se pasa revista a la reciente colaboración en Italia entre los investigadores y el ISTAT en lo que a compilación de PPP para las regiones italianas se refiere, y se presentan los resultados preliminares de estos estudios. Finalmente, este artículo pone de manifiesto interesantes futuras líneas de investigación en esta importante área, discutiendo las oportunidades y los desafíos que ofrece la disponibilidad de la fecha de alta frecuencia de los puntos de venta en forma de datos de escáner para la compilación de PPP subnacionales.
|
2022-12-04T00:58:53.956Z
|
45,558,923 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.17116/hirurgia2017964-70",
"MAG": "2754750444",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
AIM
To analyze the reduction of pain severity, time of surgery, intraoperative blood loss, incidence of unintentional lesion of dura mater, infectious complications and hospital-stay after lumbar microdiscectomy.
MATERIAL AND METHODS
The study included 104 patients aged 24-58 years (37 men and 67 women, mean age 45 years) who underwent lumbar microdiscectomy within January 2015 - June 2016. The main and control groups consisted of 48 and 56 patients with and without obesity respectively. In all cases lumbar microdiscectomy was made. Pain syndrome was assessed by visual analogue scale and Oswestry questionnaire.
RESULTS
In 6 weeks, 6 and 12 months after surgery significant improvement of both lumbar and leg pain was observed. Significantly reduced pain was stable and similar in both groups within follow-up although there was a tendency to increased pain in long-term period in group 1. Blood loss and infections were slightly higher in obese group while surgery time and hospital-stay were significantly higher in these patients.
CONCLUSION
Features of patients with excessive body weight should be considered prior to elective surgery. Probably, implants are advisable to stabilize spinal motion segment and improve the outcomes among patients with excessive body weight.
|
2022-12-20T02:20:28.502Z
|
5,086,369 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/nl504369x",
"MAG": "2329555301",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Optical activity is a common natural phenomenon, which occurs in individual molecules, biomolecules, biological species, crystalline solids, liquid crystals, and various nanosized objects, leading to numerous important applications in almost every field of modern science and technology. Because this activity can hardly be altered, creation of artificial active media with controllable optical properties is of paramount importance. Here, for the first time to the best of our knowledge, we theoretically demonstrate that optical activity can be inherent to many semiconductor nanowires, as it is induced by chiral dislocations naturally developing during their growth. By assembling such nanowires in two- or three-dimensional periodic lattices, one can create optically active quantum supercrystals whose activity can be varied in many ways owing to the size quantization of the nanowires' energy spectra. We believe that this research is of particular importance for the future development of semiconducting nanomaterials and their applications in nanotechnology, chemistry, biology, and medicine.
|
2022-12-21T01:10:46.362Z
|
232,130,710 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/acsami.1c00002",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Nitrogen-doped porous carbon spheres have attracted great interest in diversified fields owing to their unique physical and chemical properties. However, the synthesis of nitrogen-doped porous carbon spheres with hierarchical superstructures and refined micropore structures is still a challenge. Herein, we develop a molecular-scale silica templating strategy to prepare nitrogen-doped microporous carbon spheres (MCSSs) with high porosity and a well-defined micropore structure. Octa(aminophenyl) polyhedral oligomeric silsesquioxane is used as a building block in MCSS precursors to provide precise molecular-scale templating and nitrogen doping. The morphology of MCSSs can be easily tuned by choosing the proper solvent. The as-synthesized MCSS with a large surface area (2036 m2 g-1), narrow micropore size distribution, nitrogen doping, and hierarchical geometry can serve as an efficient selective adsorbent for CO2 and organic pollutants. Furthermore, the MCSS decorated with Fe-N-C active sites (MCSS-Fe) shows enhanced electrocatalytic ORR activity in alkaline solution. This novel approach may open a new avenue for controllable fabrication of porous carbon spheres with desired geometry and well-designed pore structure and show potential applications in selective adsorption and catalysis.
|
2022-12-25T17:09:25.774Z
|
255,268,293 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/CM9.0000000000002369",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract Background: A simplified protocol for regional citrate anticoagulation (RCA) using a commercial calcium-containing replacement solution, without continuous calcium infusion, is more efficient for use in continuous renal replacement therapy (CRRT). We aim to design a randomized clinical trial to compare the safety and efficacy between calcium-free and calcium-containing replacement solutions in CRRT with RCA. Methods: Of the 64 patients receiving RCA-based postdilution continuous venovenous hemodiafiltration (CVVHDF) enrolled from 2017 to 2019 in West China Hospital of Sichuan University, 35 patients were randomized to the calcium-containing group and 29 to the calcium-free replacement solution group. The primary endpoint was circuit lifespan and Kaplan–Meier survival analysis was performed. Secondary endpoints included hospital mortality, kidney function recovery rate, and complications. The amount of 4% trisodium citrate solution infusion was recorded. Serum and effluent total (tCa) and ionized (iCa) calcium concentrations were measured during CVVHDF. Results: A total of 149 circuits (82 in the calcium-containing group and 67 in the calcium-free group) and 7609 circuit hours (4335 h vs. 3274 h) were included. The mean circuit lifespan was 58.1 h (95% CI 53.8–62.4 h) in the calcium-containing group vs. 55.3 h (95% CI 49.7–60.9 h, log rank P = 0.89) in the calcium-free group. The serum tCa and iCa concentrations were slightly lower in the calcium-containing group during CRRT, whereas the postfilter iCa concentration was lower in the calcium-free group. Moreover, the mean amounts of 4% trisodium citrate solution infusion were not significantly different between the groups (171.1 ± 15.9 mL/h vs. 169.0 ± 15.1 mL/h, P = 0.49). The mortality (14/35 [40%] vs. 13/29 [45%], P = 0.70) and kidney function recovery rates of AKI patients (19/26, 73% vs. 14/24, 58%, P = 0.27) were comparable between the calcium-containing and calcium-free group during hospitalization, respectively. Six (three in each group) patients showed signs of citrate accumulation in this study. Conclusions: When compared with calcium-free replacement solution, RCA-based CVVHDF with calcium-containing replacement solution had a similar circuit lifespan, hospital mortality and kidney outcome. Since the calcium-containing solution obviates the need for a separate venous catheter and a large dose of intravenous calcium solution preparation for continuous calcium supplementation, it is more convenient to be applied in RCA-CRRT practice. Registration: Chinese Clinical Trial Registry (www.chictr.org.cn, ChiCTR-IPR-17012629)
|
2023-01-01T17:26:54.225Z
|
108,950,617 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3141/1594-23",
"MAG": "2002971090",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Soil cell tests have been used for decades to evaluate the structural performance of a variety of pipes. The structural performance of a 1500-mm (60-in.)-diameter, corrugated-exterior, smooth-interior high-density polyethylene pipe in a soil cell with two different backfill strengths is presented, and the results are compared with the values predicted theoretically. Specifiers demand assurance of the long-term hydraulic performance of smooth-interior corrugated polyethylene pipe. Fortunately, a mathematical model that allows for the estimation of the Manning value by using measurable pipe dimensions and flow characteristics is available. A discussion of the geometric changes in the interior pipe surface measured during the soil cell test is included, and an estimate of the resulting Manning values is provided. The results indicated a maximum increase in Manning values of approximately 3 or 10 percent, depending on backfill, for pipe buried within current industry recommendations for cover height.
|
2022-02-10T06:42:54.486Z
|
201,891,305 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/01605682.2019.1650618",
"MAG": "2969229489",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract This article focuses on an optimal asset allocation problem with heterogeneous discounting and stochastic income under the constant elasticity of variance (CEV) model. Heterogeneous discounting is an important non-constant discounting model, which can describe the fact that a decision maker discounts in different ways the utility derived from consumption and that of the bequest or final function. It is consistent with the fact that the concern of a decision maker about the bequest left to her descendants when she is young is not the same as that when she is old. In our model, a decision maker with stochastic income can enjoy the consumption, purchase life insurance, and invest her wealth in a risk-free asset and a risky asset whose price process satisfies the CEV model. Meanwhile, the volatility of the stochastic income arises from the risky asset. Since the problem is time-inconsistent, the Bellman’s principle of optimality does not hold. To obtain the time-consistent solution, an equilibrium strategy is calculated. By applying the game theoretic framework and solving an extended Hamilton-Jacobi-Bellman system, we derive the time-consistent consumption, investment, and life insurance strategies for both exponential and logarithmic utility functions. Finally, we provide numerical simulations to illustrate our results.
|
2022-01-27T07:55:46.796Z
|
33,665,640 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1902/JOP.1990.61.2.118",
"MAG": "2086704751",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Although several studies have concluded that calculus removal becomes more difficult as pocket depth increases, few have examined the clinical location of calculus within the intrabony defect. This study evaluated the relationship between apical calculus position and the depth and morphology of the intrabony defect. As part of an on-going study of new attachment procedures in humans, 260 intrabony defects were surgically entered in 39 patients. Using magnifying loops and fiber optics in all defects, the most apical level of calculus was grooved to serve as both a clinical and histologic reference point. Clinical measurements made prior to root debridement included the alveolar crest to base of calculus, and the base of calculus to base of defect. The type of defect was classified by the number of remaining osseous walls. Calculus has not been found apical to the groove in any histologic section. The mean distance measured clinically between the base of the calculus and the base of the defect was found to increase with the depth of the defect. This relationship did not vary with either tooth type or number of remaining osseous walls in the defect. Data analysis of this group of patients (N = 39) showed a positive correlation (r = .83) between increasing depth of intrabony defect and the distance of the most apical calculus from the defect base.
|
2022-09-12T13:04:55.876Z
|
45,270,267 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/TMEE.2011.6199549",
"MAG": "2539713869",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
As a new type of pattern recognition method, the immune clustering algorithm is successfully applied to deal with analog circuit fault diagnosis problem. Firstly, exact the fault characteristics of the circuit based on principal component analysis method. Then, calculate the clustering center as the antibody of each circuit status based on clone selection algorithm, which is so-called immunological tolerance. Lastly, regarding the testing sample as antigen, estimate the circuit status through antigen-antibody discrimination. The results show that this fault diagnosis method has high fault-coverage rate, and is easy to realize.
|
2022-12-14T06:31:55.462Z
|
121,007,404 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1063/1.1900308",
"MAG": "2064261011",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
InAsSb quantum dots (QDs) grown by metalorganic vapor phase epitaxy on In0.53Ga0.47As∕InP under different TMSb∕AsH3 flow ratios have been characterized by means of continuous wave and time-resolved photoluminescence (PL) as well as Raman scattering. It was found that the flow ratio has a very strong influence on the QD composition, PL peak energies, and carrier recombination times. While the samples prepared using low TMSb∕AsH3 flow ratios show a bimodal character with both InAs and InAsSb QDs present, in the structures grown at high flow ratios the InAsSb QDs dominate, showing strong photoluminescence intensity, fast carrier capture and slow recombination.
|
2022-12-14T06:55:56.499Z
|
119,215,664 |
{
"externalids": {
"ACL": null,
"ArXiv": "1707.00550",
"DOI": "10.1103/PhysRevA.96.013409",
"MAG": "2730206216",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Photoelectron angular distributions following the non-resonant two-photon K-shell ionization of neutral atoms are studied theoretically. Using the independent particle approximation and relativistic second-order perturbation theory, the contributions of screening and relativistic effects to the photoelectron angular distribution are evaluated. A simple nonrelativistic expression is presented for the angle-differential cross section in dipole approximation for two-photon ionization by elliptically polarized photons, and its limitations are analyzed numerically. Moreover, we show that screening effects of the inactive electrons can significantly affect the photoelectron distributions and can also lead to a strong elliptical dichroism. Numerical results are resented for the case of two-photon K-shell ionization of neutral Ne, Ge, Xe, and U atoms.
|
2022-12-16T06:15:11.015Z
|
235,209,012 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21608/EJABF.2021.168496",
"MAG": "3158335855",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Since 1990 the brackish shrimp industry has been in development and now plays a vital role in Vietnam’s aquaculture sector. In the past 30 years, the brackish shrimp practice was remarkably thriving in both horizontal and vertical dimensions. The shrimp industry is more and more intensified: from extensive to super-intensive practices. The impressive results are thanks to changing technology, methodology and species that are compatible with the seasons, environmental conditions and market demand. There are many shrimp export companies, which have promoted shrimp products, accounting for an average of 43.9% of total aquaculture exports in recent years. During the recent years, the related authorities supported shrimp farmers through training courses where they can learn about environment fluctuation and diseases. However, an increase in density of stock and expanding area caused some uncontrollable problems such as disease outbreaks, polluted water resources and abuse of drugs and chemicals in shrimp practice. Overuse of drugs and chemicals is not only harmful to natural ecosystems but also affects customers’ health due to the residual ARTICLE INFO ABSTRACT Article History: Received: Jan. 5, 2021 Accepted: March 23, 2021 Online: April 30, 2021 _______________
|
2022-12-19T18:44:01.843Z
|
205,875,344 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/NEN.0b013e3181fa44af",
"MAG": "2333996378",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
To characterize the morphological progression of neuropathy associated with immunoglobulin M-monoclonal gammopathy ofundetermined significance with anti-myelin-associated glycoprotein antibody, we assessed histopathologic features of sural nerve specimens from 15patients, emphasizing widely spaced myelin (WSM), demyelination, and tomaculous changes. The frequency of WSM correlated with that of demyelination and tomaculous appearance in teased-fiber preparations. Inlongitudinal sections at nodes of Ranvier and paranodal regions, thespaces between terminal myelin loops, particularly those adjacent to the node of Ranvier, were widened, indicating an early change before demyelination, and there was concomitant swelling of terminal myelin loops. Some conspicuously swollen terminal myelin loops were detached from the paranodal axolemma, thereby widening the nodes ofRanvier. Tomacula coexisted frequently with redundant myelin loops and WSM, particularly in the outermost layer of myelin sheaths, suggesting that loosening of the outer layers contributes to their formation. By immunofluorescence microscopy, immunoglobulin M and myelin-associated glycoprotein were colocalized in paranodal regions and Schmidt-Lanterman incisures. Confocal analysis revealed colocalization of immunoglobulin M and complement product C3d corresponding to the area of WSM. Thus, morphological changes in terminal myelin loops, formation of WSM at paranodes, and subsequent dissociation from paranodal axolemma (which may be associated with activation ofthe complement pathway) likely contribute to demyelination in thiscondition. Loosening of compact myelin seems to contribute to tomacula formation.
|
2022-12-20T08:46:59.696Z
|
219,145,228 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3386/w26603",
"MAG": "2996965803",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://doi.org/10.3386/w26603"
}
|
This essay describes and evaluates state and local business tax incentives in the United States. In 2014, states spent between $5 and $216 per capita on incentives for firms in the form of firm-specific subsidies and general tax credits, which mostly target investment, job creation, and research and development. States with higher per capita incentives tend to have higher state corporate tax rates. Recipients of firm-specific incentives are usually large establishments in manufacturing, technology, and high-skilled service industries, and the average discretionary subsidy is $178M for 1,500 promised jobs. Firms tend to accept subsidy deals from places that are richer, larger, and more urban than the average county, and poor places provide larger incentives and spend more per job. Comparing winning and runner-up locations for each deal, we find that average employment within the three-digit industry of the deal increases by roughly 1,500 jobs. While we find some evidence of direct employment gains from attracting a firm, we do not find strong evidence that firm-specific tax incentives increase broader economic growth at the state and local level.
|
2022-12-26T15:27:17.035Z
|
245,601,910 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.17323/727-0634-2021-19-4-585-600",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://jsps.hse.ru/article/download/13615/13345"
}
|
As conversation analysis shows, all talk is highly collaborative, and meaning is created dialogically and sequentially, via the concerted actions of all the participants involved. In the case of people with communication impairments, the collaborative character of talk is even more manifest. A speaker with dysarthria, for example, may communicate through typing their messages to a text-to-speech communication app or device, using a communication (alphabet) board, or gazing at objects. This article focuses on one type of co-construction effort aimed at helping an augmented speaker to communicate, a process that can be called other-initiated repair. Although this practice is a common way of achieving understanding with people who have communication needs, in some cases repair initiation is used to do more than that. In this paper, I conduct conversation analysis of a video-recording of naturalistic interactions inside a Russian-speaking family involving a 10-year-old girl with dysarthria who communicates with her parents through an eyetracker-controlled computer interface. In this case, her parents use the structural position of repair initiation on the girl’s words not only to clarify the meaning of her message but to continue the preceding polemics over the mom’s birthday present. I argue that although this is just one instance of the use of other-repair in playful communication between family members, The potentiality of providing the type of guessing which aligns with the guesser’s interests is present in other repair sequences. This can be consequential for lives of people with communication needs when done in more official settings. Studying similar repair sequences can help better delineate 'good' scaffolding strategies in co-construction of speech of someone with communication needs.
|
2022-01-27T19:40:23.803Z
|
110,473,703 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1115/IPACK2015-48274",
"MAG": "2207467887",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Data center energy consumption can be divided into three broad categories: Information Technology (IT), Electrical, and Mechanical. An efficient data center uses the least amount of non-IT energy, which is typically divided between the mechanical and electrical systems. Mechanical systems generally contribute a large portion of the non-IT energy use by providing cooling from compressor-based equipment [1,2] and because of this, strategies to reduce compressor energy consumption can lead to significant mechanical system energy savings. The most efficient way to reduce compressor energy is through elimination or significant reduction in annual runtime. This is possible with the use of integrated airside or waterside economizers.This paper demonstrates the impacts of economization in data centers through data collected from four operating facilities over the course of implementing various economizer improvement projects. System architectures include water-cooled centrifugal chiller plant with waterside economization, direct expansion air handling units (AHU) with airside economization, air-cooled centrifugal chillers with integrated waterside economization, and direct expansion computer room air conditioners (CRAC) with evaporative cooling and waterside economization. A systematic and methodical comparison of the baseline and post-conditions is discussed, comparing expected to observed economizer operating conditions. The comparison of multiple real-world scenarios revealed a range of variances in expected operation of economizer sequences to actual observations, indicating a need for close monitoring of system performance by data center operators to fully realize economizer benefits within facilities.Copyright © 2015 by ASME
|
2022-02-10T05:06:54.351Z
|
112,144,846 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2208/jscejeep.70.13",
"MAG": "2329091154",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://www.jstage.jst.go.jp/article/jscejeep/70/1/70_13/_pdf"
}
|
The local workshop for education in the (cid:12)eld of civil engineering has continuously been carried out by the industry-government-academia collaboration for (cid:12)ve years so that civil engineers could cope with the regional problem related to Aomori area. The background and circumstances of this workshop, and the originality and utility of this activity are mentioned. The summary of the (cid:12)ve-year activities, questionnaire survey about image concerning civil engineering works and so on are shown in the paper. The conclusions are obtained as follows. Through the degree-of-comprehension questionnaire to civil engineering works, it is known that an understanding and interest to civil engineering works have not spread among citizens, and the necessity for information dissemination has been recognized in common among the industry, gov-ernment and academia. Therefore, Aomori-civil-engineering-forum by the industry-government-academia collaboration has been held for the citizens. By taking a regional problem as a theme of forum, degree of comprehension of citizens gradually has increased. On the other hand, as for the continued education for a civil engineer through local workshop, it is recognized that the interest of the high school student and the college student could be pulled out by taking a theme deeply related to business to a lesson and a lecture. And, it is useful for promotion of educational improvement activities. Moreover, the necessity for engineering design education and further collaboration is recon(cid:12)rmed. 27
|
2022-06-16T08:27:33.846Z
|
42,204,148 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1287/moor.12.4.626",
"MAG": "2057643026",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Peleg established a fundamental theorem which says that convex effectivity functions are stable. He also proved its partial converse: Within the class of maximal effectivity functions, stability implies convexity. The present paper provides another partial converse: Within the class of α-effectivity functions derived from extensive game forms without chance moves, stability implies convexity. It also provides a geometric characterization of the stability condition for the latter class.
|
2022-07-29T10:51:43.657Z
|
22,107,877 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1001/ARCHINTE.1961.03620050116013",
"MAG": "1974498173",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In recent years the clinical entity of thrombotic thrombocytopenic purpura has been recognized with increasing frequency. We have recently observed a case of this syndrome in which bloody diarrhea was the primary manifestation of platelet deficiency which led to the antemortem diagnosis. Since this is a clinical situation of protean manifestations, we believe that this report will call attention to still another facet of this interesting condition. Report of Case A 65-year-old white man*was admitted to Temple University Hospital in acute respiratory distress and in an irrational, disorientated, and semistuporous state. He had apparently been in his usual health until about one week prior to admission, at which time he developed almost constant nausea and vomiting. The day before admission he developed progressive mental haziness. Past medical history included myocardial infarction 5 years previously, allergy to penicillin, and hospitalization at another institution 3 months ago for anterior chest pain.
|
2022-08-24T09:47:08.082Z
|
72,476,909 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1001/ARCHOPHT.1934.00830170063008",
"MAG": "2077749559",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In ophthalmologic practice one uses eyepads merely to protect the eyes and eye pads and bandages to apply pressure to the eyelids and to the eyeballs. Although the textbooks and the journals describe various types of eye pads and bandages, nowhere were we able to find any record of a study of the movements of the eyes while they are padded or bandaged. From a priori reasoning, we may assume that if one eye only is covered the covered eye continues to move in the directions of the movements of the uncovered eye, and from the same reasoning we may assume that if both eyes are covered tightly with bandages, no movement, or very little, takes place. In sleep it has been observed that the eyes move up. The following investigation was undertaken to study roentgenographically the movements of the eyes under cover. We were fortunate to have an
|
2022-08-28T16:47:26.647Z
|
118,308,948 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.12693/APHYSPOLA.127.1523",
"MAG": "1145092673",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Any diagnostic decision that involves imaging techniques depends not entirely on the images themselves but also on the perception and interpretation by a radiologist. In fact, such human factors appear to be a bottleneck to imaging accuracy. A better understanding of visual perception and decision-making processes seem to be necessary for the advancement and optimization of medical imaging. Therefore, research on the accuracy of medical imaging draws on techniques from a wide range of disciplines in an attempt to minimize diagnostic errors and improve the healthcare system. This short review of the psychophysical studies in the radiological domain focuses on the recent work conducted in the visual perception of nuclear medicine images and volumetric data.
|
2022-09-07T03:13:34.418Z
|
198,446,297 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.15392/BJRS.V7I2B.756",
"MAG": "2955625262",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This work contributes to enable and develop technologies to mount fast microreactors, to generate heat and electric energy, for the purpose to warm and to supply electrically spacecraft equipment and, also, the production of nuclear space propulsion effect. So, for this purpose, the Brayton Cycle demonstrates to be an optimum approach for space nuclear power. The Brayton thermal cycle gas has as characteristic to be a closed cycle, with two adiabatic processes and two isobaric processes. The components performing the cycle's processes are compressor, turbine, heat source, cold source and recuperator. Therefore, the working fluid’s mass flow runs the thermal cycle that converts thermal energy into electrical energy, able to use in spaces and land devices. The objective is numerically to model the Brayton thermal cycle gas on nominal operation with one turbomachine composed for a radial-inflow compressor and turbine of a 40.8 kWe Brayton Rotating Unit (BRU). The Brayton cycle numerical modeling is being performed with the program RELAP5-3D, version 4.3.4. The nominal operation uses as working fluid a mixture 40 g/mole He-Xe with a flow rate of 1.85 kg/s, shaft rotational speed of 45 krpm, compressor and turbine inlet temperature of 400 K and 1149 K, respectively, and compressor exit pressure 0.931 MPa. Then, the aim is to get physical corresponding data to operate each cycle component and the general cycle on this nominal operation.
|
2022-10-21T00:48:30.094Z
|
17,207,753 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1460-9568.2009.06717.x",
"MAG": "2102607756",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc2688439?pdf=render"
}
|
Substantial evidence suggests that brain regions that have been disproportionately used during waking will require a greater intensity and/or duration of subsequent sleep. For example, rats use their whiskers in the dark and their eyes during the light, and this is manifested as a greater magnitude of electroencephalogram (EEG) slow‐wave activity in the somatosensory and visual cortex during sleep in the corresponding light and dark periods respectively. The parsimonious interpretation of such findings is that sleep is distributed across local brain regions and is use‐dependent. The fundamental properties of sleep can also be experimentally defined locally at the level of small neural assemblies such as cortical columns. In this view, sleep is orchestrated, but not fundamentally driven, by central mechanisms. We explore two physiological markers of local, use‐dependent sleep, namely, an electrical marker apparent as a change in the size and shape of an electrical evoked response, and a metabolic marker evident as an evoked change in blood volume and oxygenation delivered to activated tissue. Both markers, applied to cortical columns, provide a means to investigate physiological mechanisms for the distributed homeostatic regulation of sleep, and may yield new insights into the consequences of sleep loss and sleep pathologies on waking brain function.
|
2022-12-14T09:32:48.058Z
|
248,108,976 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1361-6668/ac6631",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We report on the growth and characterization of a niobium titanium nitride (NbTiN) film on a Si substrate prepared by ultrahigh vacuum sputtering. We show that the superconducting transition temperature is lower than those of high-quality NbTiN films. Interestingly, even though the zero-temperature Ginzburg-Landau coherence length (=9.77 nm) is significantly shorter than the film thickness (=86 nm), we are still able to observe the Berezinskii-Kosterlitz-Thouless-like transition, indicating the two-dimensional (2D) signature of our three-dimensional (3D) sample. We propose that the mechanism of hidden 2D superconducting property is similar to the recently reported results of the disordered induced 3D to 2D superconductor transition. We suggest further theoretical work is required for studying our new experimental results.
|
2022-12-18T13:01:05.764Z
|
100,394,479 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/TDC.2003.1335377",
"MAG": "2105582830",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Solid-state circuit breakers can provide significant advantages in speed and functionality compared to mechanical switches. Today, several high-power semiconductors are available up to 9 kV. In contrast to conventional power electronic systems, minimizing conduction losses of solid-state devices is of greater importance than their switching performance. In addition, in today's power systems cost consideration, not only investment costs but also life cycle costs is of utmost importance. As a result, the optimization and selection of power electronic switch topologies is critical. In this paper, different semiconductors are briefly compared considering the requirements of a solid-state switch integrated into a 20 kV medium voltage grid. Based on these semiconductor characteristics, various switch topologies are developed. Next, these topologies are compared under technical and economical aspects. It is found that the technical performance or functionality of the selected topologies differs slightly. Hence, economical aspects in form of costs are the decisive factor to select a topology.
|
2022-12-20T11:09:06.801Z
|
21,862,451 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1517/14728222.7.2.187",
"MAG": "2103834862",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Neurodegenerative diseases remain a huge unmet pharmaceutical need. For some diseases such as Parkinson’s disease, there are currently only palliative therapies, and for others such as Alzheimer’s disease there are no proven therapies on the market that have any significant impact on disease progression. Recent work has suggested that cell death may play a key role in a number of neurodegenerative diseases, and halting this aberrant cell death may halt disease progression. Kinases identified in cell death pathways may be attractive targets for neurodegenerative diseases. In this review, the authors will focus on three families of related mitogen-activated protein kinases (MAPKs), namely, the extracellular signal-regulated protein kinases (ERKs), the c-Jun N-terminal kinases (JNKs) and the p38 MAPKs. The evidence for activation of each of these pathways in disease states and in models of neurodegenerative disorders will be examined. Effects of inhibitors, where available, will be discussed, and potential problems and side effects of kinase inhibitors as therapeutics will be addressed.
|
2022-12-20T21:58:22.289Z
|
208,602,301 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1101/782417",
"MAG": "2979009751",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://www.biorxiv.org/content/biorxiv/early/2020/01/20/782417.full.pdf"
}
|
Nasopharyngeal carcinoma (NPC) is a globally rare cancer, with a unique geographic distribution. In endemic areas including Southern China, the incidence is more than 20 times higher than the rest of the world.1 Although recent evidence suggests poor oral hygiene is a risk factor for NPC,2 it remains unknown whether the disease status is associated with changes in the oral microbiome. Therefore, we carried out a population-based case-control study in an endemic area of southern China.3 We analyzed microbial communities from 499 untreated incident NPC cases and 495 age and sex frequency-matched controls. Here, we show the oral microbiome is altered in patients with NPC: patients have lower microbial diversity and significant changes in the overall structure of their microbial communities which cannot be attributed to other factors. Furthermore, the combination of two closely related amplicon sequence variants (ASVs) from Granulicatella adiacens an individual carried were predicted by disease status. These ASVs sat at the center of a network of closely-related co-excluding organisms, suggesting that NPC may be associated with subtle changes in the oral microbiome.
|
2022-12-19T00:34:44.655Z
|
201,961,334 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.33024/.V3I1.732",
"MAG": "2969958983",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Penelitian ini menggunakan desain analitik, rancangan cross sectional dalam bentuk univariat dan bivariat (uji chi square). Sampel berjumlah 35orang. Dengan variabel independen adalah faktor-faktor yang mempengaruhi status gizi pada balita usia 1-4 tahun. Dan variabel dependen adalah status gizi pada balita usia 1-4 tahun. Hasil penelitian menemukan tidak ada hubungan pola makan (p = 0,042) dan riwayat pendidikan ibu (p = 0,011) dengan status gizi balita usia 1-4 tahun. Ada hubungan riwayat penyakit infeksi (p = 0,013), pengetahuan ibu tentang gizi (p = 0,030), sikap ibu (p = 0,012), jumlah anggota keluarga (p = 0,007), pemanfaatan pelayanan kesehatan (p = 0,039) dan pendapatan keluarga (p = 0,004) dengan status gizi balita usia 1-4 tahun di wilayah kerja Puskesmas Rajabasa Indah kota Bandar Lampung tahun 2014. Disarankan bagi masyarakat untuk lebih mengetahui faktor penyebab masalah gizi pada balita, sehingga diharapkan dapat meningkatkan pencegahan terjadinya gizi buruk pada balita, dengan mengikuti penyuluhan gizi yang dilakukan pihak puskesmas dan mengikuti konseling gizi, bagi tenaga kesehatan khususnya di bidang Kesehatan Ibu dan Anak (KIA) agar dapat meningkatkan pelayanan kesehatan pada balita dan menjalin kerjasama dengan sektor lain dalam mempromosikan pentingnya status gizi pada balita
|
2022-02-08T05:00:43.818Z
|
84,652,854 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1471-8286.2007.01873.X",
"MAG": "2035917109",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Twelve polymorphic microsatellite loci were isolated and characterized from an AC-enriched genomic library of Nothotsuga longibracteata. The average allele number of these microsatellites was 8.3 per locus, ranging from two to 13. The ranges of observed and expected heterozygosities were 0.03–0.97 and 0.09–0.88, respectively. These polymorphic markers provide useful tools for the study of evolutionary history and conservation genetics of N. longibracteata.
|
2022-06-29T18:53:10.457Z
|
125,679,888 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1051/EPJCONF/201818202067",
"MAG": "2776573951",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The electroweak sector of the Standard Model can be tested by precision measurements of its fundamental parameters, such as the W boson mass or the electroweak mixing angle. In this contribution we present the first measurement of the W boson mass, based on the 7 TeV data set corresponding to an integrated luminosity of 4.6 fb−1. With this data set the detector and physics modelling have been studied in great detail, leading to an overall uncertainty of 19 MeV. The ATLAS collaboration also performed a new precise triple differential Z/γ∗ Drell-Yan cross-section measurement as a function of the dilepton mass, the dilepton rapidity and cos θ∗ defined in the Collins-Soper frame. This measurement provides sensitivity to the PDFs and the Z forward-backward asymmetry, AFB, which is derived and will be presented. The latter builds the foundation for a possible future extraction of the weak-mixing angle. The production of jets in association with vector bosons is an important process to study perturbative QCD in a multi-scale environment. The ATLAS collaboration has performed new measurements of vector boson plus jets cross sections, differential in several kinematic variables, in proton-proton collision data, taken at center-of-mass energies of 8 TeV and 13 TeV. These measurements are presented and compared to state-of-the art theory predictions. They are sensitive to higher-order pQCD effects, and can be used to constrain the proton structure. In addition, we present a new measurement of the splitting scales of the kt jet-clustering algorithm for final states containing a Z-boson candidate at a centre-of-mass energy of 8 TeV.
|
2022-07-08T00:06:30.240Z
|
201,068,677 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/MED.2019.8798494",
"MAG": "2969150917",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The design of a class of predefined-time stabilizing controller for a class uncertain nonholonomic systems in chained form is investigated in this paper. First, some modifications to the classical fixed-time algorithms for first and second order systems are introduced. These modified algorithms, which are developed under the concept of predefined-time stability, reduce the settling time overestimation drawback suffered by the classical fixed-time algorithm. Unlike current finite-time and fixed-time schemes, an upper bound of the settling time is easily tunable through a simple selection of the parameters of the controllers. Then, based on the developed first and second-order algorithms, a switching control strategy is designed to guarantee the predefined-time stability of the chained-form nonholonomic system. Finally, a simulation example is presented to show the effectiveness of the proposed method.
|
2022-09-01T20:10:13.084Z
|
251,282,275 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1302/2046-3758.118.BJR-2021-0565.R1",
"MAG": null,
"PubMedCentral": "9396926"
},
"license": null,
"status": null,
"url": null
}
|
Aims We aimed to develop a gene signature that predicts the occurrence of postmenopausal osteoporosis (PMOP) by studying its genetic mechanism. Methods Five datasets were obtained from the Gene Expression Omnibus database. Unsupervised consensus cluster analysis was used to determine new PMOP subtypes. To determine the central genes and the core modules related to PMOP, the weighted gene co-expression network analysis (WCGNA) was applied. Gene Ontology enrichment analysis was used to explore the biological processes underlying key genes. Logistic regression univariate analysis was used to screen for statistically significant variables. Two algorithms were used to select important PMOP-related genes. A logistic regression model was used to construct the PMOP-related gene profile. The receiver operating characteristic area under the curve, Harrell’s concordance index, a calibration chart, and decision curve analysis were used to characterize PMOP-related genes. Then, quantitative real-time polymerase chain reaction (qRT-PCR) was used to verify the expression of the PMOP-related genes in the gene signature. Results We identified three PMOP-related subtypes and four core modules. The muscle system process, muscle contraction, and actin filament-based movement were more active in the hub genes. We obtained five feature genes related to PMOP. Our analysis verified that the gene signature had good predictive power and applicability. The outcomes of the GSE56815 cohort were found to be consistent with the results of the earlier studies. qRT-PCR results showed that RAB2A and FYCO1 were amplified in clinical samples. Conclusion The PMOP-related gene signature we developed and verified can accurately predict the risk of PMOP in patients. These results can elucidate the molecular mechanism of RAB2A and FYCO1 underlying PMOP, and yield new and improved treatment strategies, ultimately helping PMOP monitoring. Cite this article: Bone Joint Res 2022;11(8):548–560.
|
2022-09-30T00:40:39.251Z
|
67,858,366 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/ma12030434",
"MAG": "2914062303",
"PubMedCentral": "6384798"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/1996-1944/12/3/434/pdf?version=1548924541"
}
|
This study refers to the doping of organic semiconductors by a simple reaction between copper phthalocyanine and tetrathiafulvalene or tetracyanoquinodimethane. The semiconductor films of copper phthalocyanine, doped with tetrathiafulvalene donor (CuPc-TTF) and tetracyanoquinodimethane acceptor (CuPc-TCNQ) on different substrates, were prepared by vacuum evaporation. The structure and morphology of the semiconductor films were studied with infrared (IR) spectroscopy, X-ray diffraction (XRD), and scanning electron microscopy (SEM). The absorption spectra for CuPc-TTF, recorded in the 200–900 nm UV–vis region for the deposited films, showed two peaks: a high energy peak, around 613 nm, and a second one, around 695 nm, with both peaks corresponding to the Q-band transition of the CuPcs. From the spectra, it can also be seen that CuPc-TTF has a B-band at around 330 nm and has a bandgap of approximately 1.4 eV. The B-band in the CuPc-TCNQ spectrum is quite similar to that of CuPc-TTF; on the other hand, CuPc-TCNQ does not include a Q-band in its spectrum and its bandgap value is of approximately 1.6 eV. The experimental optical bandgaps were compared to the ones calculated through density functional theory (DFT). In order to prove the effect of dopants in the phthalocyanine semiconductor, simple devices were manufactured and their electric behaviors were evaluated. Devices constituted by the donor-acceptor active layer and by the hollow, electronic-transport selective layers, were deposited on rigid and flexible indium tin oxide (ITO) substrates by the vacuum sublimation method. The current–voltage characteristics of the investigated structures, measured in darkness and under illumination, show current density values of around 10 A/cm2 for the structure based on a mixed-PET layer and values of 3 A/cm2 for the stacked-glass layered structure. The electrical properties of the devices, such as carrier mobility (μ) were obtained from the J–V characteristics. The mobility values of the devices on glass were between 1.59 × 109 and 3.94 × 1010 cm2/(V·s), whereas the values of the devices on PET were between 1.84 × 109 and 4.51 × 109 cm2/(V·s). The different behaviors of the rigid and flexible devices is mainly due to the effect of the substrate.
|
2022-12-02T10:13:25.350Z
|
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