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255M
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237,301,602 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1742-6596/1992/3/032118",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://doi.org/10.1088/1742-6596/1992/3/032118"
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|
Artificial intelligence is gradually widely used in our country, and with the development of the information age, the image recognition technology derived from artificial intelligence is also gradually known to people. The main principle of image recognition technology is the substitution of computer to artificial. These working principles can not be separated from the traction function of artificial intelligence, so as to realize many processing and judging of data information. Under the trend of gradual development of computer technology, the security and process of recognition data should be analyzed under the continuous extension of image recognition technology. In this paper, the image recognition technology in artificial intelligence will be analyzed and studied in depth, and the image recognition technology will be briefly summarized.
|
2022-12-14T18:13:17.217Z
|
144,538,411 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1080/10720162.2011.584057",
"MAG": "2036544773",
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},
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"status": null,
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|
Because of the association that researchers have recently delineated between compulsive sexual behavior and the Human Immunodeficiency Virus, Sexually Transmitted Infections, and drug abuse, it is paramount that a psychometrically sound measure of compulsive sexual behavior is made available to all healthcare professionals working in disease prevention and other areas. This article reports the findings from a psychometric analysis of the Compulsive Sexual Behavior Inventory (CSBI) in a sample of 482 racially and ethnically diverse men and women. The current study provides further evidence for the score reliability and the score validity of the CSBI in this sample. Construct-related validity was assessed using the multi-trait multi-method approach. These analyses extend previous findings for the psychometric properties of the CSBI in a more diversified sample.
|
2022-12-18T09:53:01.008Z
|
39,829,892 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1515/znc-1987-1-215",
"MAG": "2225353508",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "HYBRID",
"url": "https://www.degruyter.com/document/doi/10.1515/znc-1987-1-215/pdf"
}
|
Abstract Cell-free extracts from oak (Quercus robur) leaves catalyze the transfer of the galloyl-moiety of β-glucogallin (1-O-galloyl-β-D-glucopyranose) specifically to the 6-position of the same compound, yielding 1,6-di-O-galloyl-β-D-glucopyranose, an intermediate of gallotannin biosynthesis, β- Glucogallin thus functions as both donor and acceptor molecule in this reaction. The partial purification and some general properties of this new acyltransferase are reported.
|
2022-12-18T11:49:14.534Z
|
2,794,620 |
{
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"ArXiv": "gr-qc/9405004",
"DOI": "10.1103/PhysRevD.51.2801",
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|
We present a class of theories of two-dimensional gravity which admits homogeneous and isotropic solutions that are nonsingular and asymptotically approach a FRW matter-dominated universe at late times. These models are generalizations of two-dimensional dilaton gravity and both vacuum solutions and those including conformally coupled matter are investigated. In each case our construction leads to an inflationary stage driven by the gravitational sector. Our work comprises a simple example of the nonsingular universe'' constructions of Brandenberger and co-workers.
|
2022-12-20T17:22:39.706Z
|
237,879,749 |
{
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"ArXiv": null,
"DOI": "10.1080/09720529.2020.1800217",
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|
Abstract Let T = (V, E) be a tree of order n. Let f : E → {1, 2, 3, … } be an injective edge labeling of T. The weight of a path P is the sum of the labels of the edges of P and is denoted by w(P). If the set of weights of the paths in T is , then f is called a Leech labeling of T and a tree which admits a Leech labeling is called a Leech tree. In this paper, we introduce a new parameter called Leech index which gives a measure of how close a tree is towards being a Leech tree. Let f : E → {1, 2, 3, … } be an edge labeling of T such that both f and w are injective. Let S denote the set of all weights of the paths in T. Let kf be the positive integer such that {1, 2, 3, … , k f } ⊆ S and kf + 1 ∉ S. Then k(T) = max kf , where the maximum is taken over all such edge labelings f is called the Leech index of T. In this paper, we determine the Leech index of several families of trees and obtain bounds for this parameter.
|
2022-12-21T15:14:25.733Z
|
108,511,018 |
{
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"ArXiv": null,
"DOI": "10.1117/12.2041091",
"MAG": "1998643922",
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"url": null
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|
The full-specification Super Hi-Vision image sensor realizes 4320 lines of 7680 pixels at 120 frames per second with 12- bit resolution. This sensor requires both high sensitivity and high frame rate, because the illumination per frame decreases as the frame rate increases. Sensitivity of the back-side-illuminated sensor is estimated to be 1.65 times higher than that of the front-side-illuminated sensor, which is calculated from the product of light gathering power of 1.32 times and internal quantum efficiency of 1.25 times. The advantage at high frame rate is that the rising time of the driving voltage waveform of a pixel in the back-side-illuminated sensor is three times faster than that of the front-sideilluminated sensor. To realize a back-side-illuminated structure with a 10 μm-thick photo-electric conversion element, we investigated the cross-sectional potential profile using an np double epitaxial layer structure. Concentrations of the nand p- epitaxial layers were studied, aiming to achieve a transit time of less than 2.3 ns and a potential barrier height of more than 0.117 eV.
|
2022-02-10T06:59:47.344Z
|
62,686,087 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.4028/www.scientific.net/AMM.135-136.1072",
"MAG": "2007618950",
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},
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}
|
In this paper, we used web Service Bridge to solve the ASP.NET AJAX client cannot directly invoke the remote web service problem caused by the security restrictions of JavaScript. Web Service Bridge makes the AJAX client invoke the remote web services as if it invokes the local web services by defining the local service proxy for remote web service in XML declaration. The example demonstrates that, compared to the traditional method of programming local service proxy, web Service Bridge is more convenient and efficient to implement a large number of remote web service invocations in Mushup application.
|
2022-02-11T14:28:31.489Z
|
112,625,070 |
{
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"ArXiv": null,
"DOI": "10.1002/9781118275658",
"MAG": "2502222881",
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},
"license": null,
"status": "CLOSED",
"url": null
}
|
This book is the first to consolidate current research and to examine the theories of electromagnetic computation methods in relation to lightning surge protection. The authors introduce and compare existing electromagnetic computation methods such as the method of moments (MOM), the partial element equivalent circuit (PEEC), the finite element method (FEM), the transmission-line modeling (TLM) method, and the finite-difference time-domain (FDTD) method. The application of FDTD method to lightning protection studies is a topic that has matured through many practical applications in the past decade, and the authors explain the derivation of Maxwell’s equations required by the FDTD, and modeling of various electrical components needed in computing lightning electromagnetic fields and surges with the FDTD method. The book describes the application of FDTD method to current and emerging problems of lightning surge protection of continuously more complex installations, particularly in critical infrastructures of energy and information, such as overhead power lines, air-insulated sub-stations, wind turbine generator towers and telecommunication towers.
|
2022-11-28T18:36:22.442Z
|
237,528,275 |
{
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"ArXiv": null,
"DOI": "10.2139/ssrn.3922003",
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|
This paper studies the effect of trade opportunities on a seller’s incentive to acquire information through experimentation. I characterize the unique equilibrium outcome and discuss the effects of variations in the information structure on the probability of trade. The main result is that more accurate information for the buyer can reduce social welfare. Efficiency requires that the buyer offers a price that the seller always accepts and that the seller experiments when it is socially optimal to do so. When the buyer receives very informative signals about positive experimentation outcomes, the absence of such a signal can induce the buyer to purchase the good only with low but known quality at a low price. If the buyer receives an informative signal about negative experimentation outcomes, the seller might prefer to not experiment so as to avoid the risk of generating a negative outcome that could trigger the buyer to reduce her offer.
|
2022-12-04T16:33:46.200Z
|
45,786,377 |
{
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"DOI": "10.1111/j.1399-3054.2010.01393.x",
"MAG": "2091009650",
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"license": null,
"status": "GREEN",
"url": "http://210.75.237.14/bitstream/351003/22518/1/2010e0037h.pdf"
}
|
Responses of males and females to salinity were studied in order to reveal sex-specific adaptation and evolution in Populus cathayana Rehd cuttings. This dioecious tree species plays an important role in maintaining ecological stability and providing commercial raw material in southwest China. Female and male cuttings of P. cathayana were treated for about 1 month with 0, 75 and 150 mM NaCl. Plant growth traits, gas exchange parameters, chlorophyll pigments, intrinsic water use efficiency (WUEi), membrane system injuries, ion transport and ultrastructural morphology were assessed and compared between sexes. Salt stress caused less negative effects on the dry matter accumulation, growth rate of height, growth rate of stem base diameter, total number of leaves and photosynthetic abilities in males than in females. Relative electrolyte leakage increased more in females than in males under salinity stress. Soil salinity reduced the amounts of leaf chlorophyll a, chlorophyll b and total chlorophyll, and the chlorophyll a/b ratio more in females than in males. WUEi decreased in both sexes under salinity. Regarding the ultrastructural morphology, thylakoid swelling in chloroplasts and degrading structures in mitochondria were more frequent in females than in males. Moreover, females exhibited significantly higher Na(+) and Cl(-) concentrations in leaves and stems, but lower concentrations in roots than did males under salinity. In all, female cuttings of P. cathayana are more sensitive to salinity stress than males, which could be partially due to males having a better ability to restrain Na(+) transport from roots to shoots than do females.
|
2022-12-20T09:10:42.245Z
|
238,095,607 |
{
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"DOI": "10.22059/JES.2021.310449.1008072",
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|
موقعیت جغرافیایی شهر تهران و قرارگیری آن در میان کوههای البرز،استقرار کارخانهها در اطراف شهر و حجم زیادخودروهای در حال تردد ازجمله عواملی هستند که با استقرار مواد آلاینده،آسایش ساکنان را به خطر انداخته و منجر به آشفتگی در زندگی شهری شدهاند.این مسائل ضرورت ایجادآرامش و دسترسی به طبیعت را دو چندان کرده است.به دلیل ارزش بالای زمین،بهکارگیری سطوح بلااستفاده از جمله بام ساختمانها،راهحل مناسبی جهت گسترش فضای سبز بهشمار میرود.در این راستا پژوهش حاضر با هدف بررسی توجیهپذیری اقتصادی و اقتصادی-محیطزیستی احداث بام سبز درسطح منطقه 9 شهرداری تهران، در سال 1398 صورت گرفته است.برای این منظور از آزمون انتخاب و شاخصهای ارزش حال خالص، نرخ بازده داخلی و نسبت فایده به هزینه،بهره گرفته شده است.نتایج نشاندهنده عدم توجیهپذیری احداث بام سبز از بعد اقتصادی در منطقه مورد مطالعه است.درحالی که لحاظ ارزش منافع محیطزیستی در ارزیابی، منجر به ایجاد ارزش حال خالصی برابر 349/11 میلیون ریال بر متر مربع و نرخ بازده داخلی 53 درصد میشود.همچنین نتایج بیانگرآن است که ارزش محیطزیستی که شهروندان این منطقه برای هرمترمربع از بام سبز قایلند و حاضرند برای احداث آن بپردازند،بهطور میانگین معادل 44/5 میلیون ریال به ازای هرمترمربع است. در این حالت نسبت فایده به هزینه معادل 92/1 خواهد بود.
|
2022-01-24T18:58:23.030Z
|
180,000,015 |
{
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"ArXiv": null,
"DOI": "10.31743/abmk.8552",
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"license": null,
"status": "BRONZE",
"url": "https://czasopisma.kul.pl/abmk/article/download/8552/7314"
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|
<jats:p>-</jats:p>
|
2022-01-23T03:26:12.716Z
|
191,002,391 |
{
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"ArXiv": null,
"DOI": "10.2307/431419",
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|
Acknowledgments Introduction Patricia Erens I. Critical Methodology: Women and Representation Introduction Positive Images Screening Women's Films Linda Artel and Susan Wengraf There's More to a Positive Image Than Meets the Eye Diane Waldman The Place of Women in the Cinema of Raoul Walsh Pam Cook and Claire Johnston Visual Pleasure and Narrative Cinema Laura Mulvey Film and the Masquerade Theorizing the Female Spectator Mary Ann Doane Hitchock, Feminism, and the Patriarchal Unconscious Tania Modleski Women and Respresentation Can We Enjoy Alternative Pleasure? Jane Gaines II. Rereading Hollywood Films Introduction Gentlemen Consume Blondes Maureen Turim Pre-text and Text in Gentlemen Prefer Blondes Lucie Arbuthnot and Gail Seneca The Case of the Missing Mother Maternal Issues in Vidor's Stella Dallas E. Ann Kaplan "Something Else Besides a Mother" Stella Dallas and the Maternal Melodrama Linda Williams Seduced and Abandoned Recollection and Romance in Letter from an Unkown Woman Lucy Fischer Illicit Pleasures Feminist Spectators and Personal Best Elizabeth Ellsworth White Privilege and Looking Relations Race and Gender in Feminist Film Theory Jane Gaines III. Critical Methodology: Feminist Filmmaking Introduction The Political Aesthetics of the Feminist Documentary Film Julia Lesage Feminism, Film, and Public History Sonya Michel Textual Politics Annette Kuhn In the Name of Feminist Film Criticism B. Ruby Rich Rethinking Women's Cinema Aesthetics and Feminist Theory Teresa de Lauretis Dis-Embodying the Female Voice Kaja Silverman IV. Assessing Films Directed by Women Introduction Images and Women Robin Wood Unspoken and Unsolved Tell Me a Riddle Florence Jacobowitz and Lori Spring Desperately Seeking Difference Jackie Stacey Female Narration, Women's Cinema Helke Sander's The All-Round Reduced Personality/Redupers Judith Mayne Feminist or Tendentious? Marleen Gorris's A Question of Silence Mary C. Gentile Anti-Porn Soft Issue, Hard World B. Ruby Rich Variety The Pleasure in Looking Bette Gordon Glossary Selected Bibliography Index
|
2022-09-16T02:28:20.150Z
|
5,955,488 |
{
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"DOI": "10.4236/JCT.2011.25096",
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"license": null,
"status": null,
"url": null
}
|
Breast cancer cell growth can be inhibited in vivo by retinoid X receptor (RXR) specific retinoids. In both animal and cell culture studies, omega-3 fatty acids share growth regulatory effects similar to those of RXR specific retinoids (rexinoids). One synthetic rexinoid, bexarotene (LCD 1069, Targretin), is used clinically to treat cancer patients. Of concern is that some patients are unable to tolerate high doses of such treatment drugs. We hypothesized that n-3 fatty acids and bexarotene may work synergistically to slow breast cancer cell growth. To test our hypothesis, we used MCF-7 human mammary carcinoma cells and an in vitro cell culture model. We investigated the relationship between the omega-3 fatty acids docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) alone and in conjunction with bexarotene in slowing MCF-7 cell growth. Following a 72 hr incubation with the respective treatments, bexarotene enhanced cell growth (p < 0.05) while DHA showed a strong growth inhibitory effect which was not enhanced by the addition of bexarotene (p < 0.05). EPA alone was not effective in altering cell growth (p < 0.05). Interestingly, when combined with bexarotene, EPA was more effective at slowing cell growth than when cells received EPA alone. Thus, select omega-3 fatty acids alone are more effective than bexarotene in slowing MCF-7 cell progression. However, the use of the RXR-selective retinoids may enhance the growth regulatory mechanisms of the fatty acid EPA.
|
2022-10-14T00:27:54.334Z
|
98,077,568 |
{
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"DOI": "10.1039/B212308H",
"MAG": "2164522541",
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}
|
Herein, we introduce an extremely ‘soft’ tecton, which interacts via
‘soft’ synthons displaying an unprecedented variety of supramolecular architectures in the solid state. Hexakis(organoamino) cyclotriphosphazene derivatives, (RNH)6P3N3, contain a polar core comprising an equatorial belt of three ring nitrogen atoms and six NH functions which is sandwiched between hemispheres of lipophilic substituents R. A range of derivatives equipped with hydrocarbon side chains were synthesised and structurally characterised including R =
tert-butyl (1), cyclohexyl (2), iso-propyl (3), benzyl (4), 2-phenylethyl (5), iso-butyl (6), phenyl (7), p-tolyl (8), n-propyl (9), allyl (10), propargyl (11) and methyl (12). The study shows that subtle modifications of the lipophilic periphery lead to considerable changes in the solid-state aggregation pattern. With the exception of 1 all solid-state structures show intermolecular NH⋯N bonding with motifs containing one, two, three and four H-bridges. Supramolecular architectures include monomer (1), dimer (2), cyclic hexamer (3), zigzag chain (4, 6), linear chain (5·thf, 7, 8), double chain (9), graphite-type sheet (10), rectangular grid (11) and hexagonal close-packed sheet (12). The structural variety is due to easy rotation around exocyclic P–N bonds, which allows variable directionalities of all six N–H bonds. M.O. calculations on the gas phase dimer of (H2N)6P3N3 mirror the H-bridging motifs observed in crystal structures of (RNH)6P3N3 derivatives.
|
2022-12-17T08:56:30.686Z
|
210,375,119 |
{
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"DOI": "10.6255/JWGS.2012.30.83",
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|
The Gender Equity Education Act of 2004 marked the beginning of gender equity education in schools, including LGBT education. However, the practice of LGBT education has not been successful in Taiwan schools. This study observes the Taiwan Tongzhi Hotline Association (TTHA) as its focus. Through the experiences of TTHA's LGBT movement in schools, this work discusses the gap between the law and practice. The findings show that LGBT education remains marginal in gender education. In practice, the curriculum arrangement of a school limits LGBT education, and many educators have considered gender education as a matter of sex equality, which marginalizes LGBT education. Lastly, this study recognizes the original intention of the Gender Equity Education Act. LGBT education would be practiced in classes if it had more institutional developments of teachers and systematic LGBT courses.
|
2022-01-27T01:59:23.963Z
|
154,055,582 |
{
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"DOI": "10.15837/AIJJS.V8I1.955",
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}
|
Appeared with the declared intention to ”meet the requirements of a dynamic present”, by: “the newly promoted solutions, the revision of some classical institutions or emphasis on certain internationally recognized principles, not implemented in the Romanian space yet”, the new Civil Code does not seem to integrate the environmental and related issues in the dynamics of the present. Moreover, except for some modest norms – such as art. 539 par. 2 which includes in the category of movables “the electromagnetic waves or those assimilated to them, as well as the energy of any kind” and art. 603 which provides the obligation of the owner to “observe the tasks concerning the protection of the environment and the action of ensuring good neighbourhood” – nothing entitles us to assert that the new Civil Code “makes valuable use of provisions of European law instruments”. It is known that the basic treaties of the European Union – the Treaty on European Union and the Treaty on the Functioning of the European Union – in numerous articles, establish the sustainable development of Europe and of the planet, the promotion of solidarity between generations and a high level of protection and enhancement of the quality of the environment as primary objectives of the European Union. This is the reason why art. 11 TFEU imposes that “environmental protection requirements must be integrated into the definition and implementation of the Union policies and activities”.
|
2022-02-09T02:01:19.415Z
|
44,625,539 |
{
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"ArXiv": null,
"DOI": "10.1111/ans.12723",
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|
common, the incidence of them requiring operative intervention is rare with figures between 1 and 14% quoted in the literature. Most foreign bodies therefore pass freely through the gastrointestinal tract. If trapped and subsequent perforation occurs, it tends to be at areas with great angulation such as the ileocaecal valve, junctions along the duodenum, the appendix and the haustra of the large intestine. Perforation of the duodenum remains exceedingly rare and even more so if involving nearby vascular structures. Depending on the calibre of the DCF and the size, location and relative ease of removing the trapped foreign body, significant morbidity and mortality have been reported. This is secondary to overwhelming haemorrhage, sepsis and iatrogenic complications. Endoscopic retrieval is one acceptable approach in the stable patient with localized perforation. Due to the rarity of this presentation, there is not any evidence to compare whether open or endoscopic approach has the best outcome. This is because open management is usually associated with significant patient morbidity because of the need to mobilize and open retroperitoneal structures with consequent risk of duodenal fistulas and bleeding. Also open operation is the most common approach in the unstable patient and given the nature of this condition, it is more common that a patient would present in an unstable state and therefore undergo an open approach. Our case is one example of where endoscopic retrieval has been successful. Pulmonary embolization as a consequence of DCF has been reported even less frequently. The clot lodged in the filter at time of retrieval leads us to believe that its placement in this case helped prevent and/or minimized pulmonary seeding and septic emboli. In summary, the key points of this case are that CT imaging is the diagnostic imaging of choice for foreign body perforation of the duodenum. Endoscopic retrieval can be considered in selected patients and was shown to be successful in our case. Recognizing IVC involvement and treatment with intravenous filter may minimize septic thromboembolic complications.
|
2022-02-26T12:38:18.368Z
|
25,977,583 |
{
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"DOI": "10.18565/CARDIO.2015.5.66-71",
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|
UNLABELLED
There is an urgent need to create adapted for the Russian population of the recommendations in order to improve the efficiency and automation of the process of informing patients about the correct (sanogennykh) behavior in the heat. The proposed health WHO recommendations in 2010 year are difficult to perception, understanding and subsequent patient use without consulting a doctor.
THE GOAL
creating and testing adapted for the Russian population recommendations for sanogennykh behavior during the summer heat on the basis of the recommendations of the WHO in 2010.
MATERIALS AND METHODS
155 persons older than 30 years, 93 people were adapted recommendations (group 1), 62--"classic" WHO recommendations 2010 (group 2). The groups were comparable in terms of the main clinical and demographic characteristics. Results: in the summer 2014 heat waves observed 2: 4 and 10 days, the maximum temperature of 32.7 °C. On the "deterioration of health during a heat wave", complained 20.6% of patients receiving tailored recommendations, and 40%--classic (p = 0.008). The number of cardiovascular complications in group 1 was 0.0 (0.3, 1.4) in group 2--0.0 (0.6, 2.4; p = 0.000). Most effective recommendations noted patients with coronary heart disease and hypertension (87.5%; 9 of them were adapted recommendations 4--"classic") and chronic heart failure (80%; all they got adapted recommendations).
CONCLUSION
customized recommendations sanogennykh behavior during heat waves can be recommended for use in clinical practice for patients with cardiovascular diseases.
|
2022-02-12T16:31:23.503Z
|
208,251,419 |
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"DOI": "10.4067/S0717-95022006000400003",
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"status": null,
"url": null
}
|
Se estudiaron con herramientas morfologicas, los efectos de diferentes dosis de Losartan sobre el remodelamiento cardiovascular, en ratas deficientes en oxido nitrico. 30 ratas Wistar, con 15 semanas de edad, fueron separadas en 6 grupos. control (C), L-NAME (LN), y 4 grupos en que administro LN junto con Losartan, en diferentes dosis (1, 5, 20 y 40 mg/kg/dia). El L-NAME fue administrado durante 9 semanas y la administracion de Losartan se inicio en la segunda semana de experimentacion. Se estudiaron el corazon, la parte toracica de la aorta y la arteria mesenterica craneal, con microscopia de luz y estereologia. La presion arterial (PA) aumento desde la primera semana de administracion de L-NAME. El tratamiento con Losartan, en las dosis de 20 y 40 mg/kg/dia, fue eficiente para reducir la PA despues de la septima semana de tratamiento. El remodelamiento cardiaco adverso en el grupo LN se caracterizo por intensa fibrosis intersticial, disminucion de la microvascularizacion miocardica e hipertrofia y consecuente perdida de cardiomiocitos. La estructura de la pared de la aorta (densidad por area de nucleos de celulas musculares lisas y densidad de superficie de lamelas), y la relacion media/luz de la arteria mesenterica craneal, tambien fueron muy alteradas por la administracion de L-NAME. Solo en una dosis igual o mayor que 20 mg/kg/dia, el Losartan tuvo efecto benefico tratando estas alteraciones. En conclusion, tanto el corazon como la pared arterial de ratas deficientes en oxido nitrico, presentan un proceso de remodelamiento acentuado, y este es eficientemente tratado con Losartan en diferentes dosis. La eficiencia del tratamiento con Losartan en el modelo de bloqueo de la sintesis de oxido nitrico se correlaciona con el efecto hipotensor de la droga, principalmente en las dosis mas elevadas
|
2022-07-25T02:39:44.774Z
|
62,364,244 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.9723/JKSIIS.2015.20.6.001",
"MAG": "2327045300",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this paper, we propose a spectral efficient orthogonal frequency division multiple access(OFDMA) transmission system using multiple relays for a shadow area. The performance of the proposed OFDMA system in a shadow area can be improved by applying space-frequency(SF) block code over relaying multi-path channels. A simple channel cyclicity restoration method is also added in the proposed OFDMA system without cyclic prefix(CP) to recover the destruction of channel cyclicity due to the lack of CP. Simulation results show that the proposed OFDMA system without CP is almost same as that of the conventional OFDMA system with sufficient CP, which increases the spectral efficiency of the system.
|
2022-08-03T04:15:28.859Z
|
147,555,070 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2307/586860",
"MAG": "2327259179",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
-T>HESE NOTES are primarily concerned with the manner and | extent to which statistical surveys can be used in social administ tration. They concentrate on the ways in which the social services may be brought into action, the aim being to analyse the form of such procedures in terms of a series of categories, each representing one component of the total process. This analysis is made in general terms, because it seetned important to be able to apply a common approach to the study of any of the Social Services; examples, however, are drawn from a wide variety of sources. It should be emphasized that these notes contain only a tentative exploration of research methodology in this field; it is hoped, however, that they may be of value in assisting the development of statistical research in social administration. The aspects of social and political life studied under the title of Social Administration were authoritatively delimited in Professor Titmuss' inaugural lecture:l 'On the one hand then, we are interested in the machinery of administration which organizes and dispenses various forms of social assistance; on the other, in the lives, the needs, and the mutual relations of those members of the community for whom the services are provided by reason of their belonging to that community.' In short any study must be concerned with one or both of two fundamental issues: first, the ascertainment of need; second, the nature and quality of administration. The third important topic, the extent to which need is satisfied is, methodologically, essentially the same as the first, the ascertainment of need, but involves comparisons 'before and after' assistance has been given. Five years after Professor Titmuss' lecture one might add that possibly the most interesting development of the subject has been in studies which have attempted to link these two interests, and a fair number of examples can now be cited: Early Leaving,2 Deprived Children,3 the work
|
2022-09-15T03:46:14.928Z
|
213,540,881 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/1753495X19884484",
"MAG": "2994397054",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This review paper outlines the definition, pathophysiology, and potential maternal health consequences of cellular fetal microchimerism, the maternal acquisition of intact cells of fetal origin during pregnancy. Increased rates and amounts of cellular fetal microchimerism are associated with several placental syndromes, including preeclampsia and fetal growth restriction. The discovery of cellular fetal microchimerism and methods of detection are briefly outlined, and we present the mechanisms hypothesized to govern pregnancy-related and long-term maternal health effects of cellular fetal microchimerism. Specifically, we discuss the potential implications of cellular fetal microchimerism in wound healing, autoimmunity, cancer, and possibly cardiovascular disease. Cellular fetal microchimerism represents a novel area of research on maternal and transgenerational health and disease, providing exciting opportunities for developing new disease biomarkers and precision medicine with targeted prophylaxis against long-term maternal disease.
|
2022-12-04T00:23:07.636Z
|
97,832,415 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/J.2050-0416.1955.TB02792.X",
"MAG": "2054493191",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The raw materials of brewing would appear to contain amounts of copper which vary from about 5 p.p.m. in barley up to some 85 p.p.m. in hops, the latter showing considerable fluctuation. The mean figure for brewery pitching yeast over a long period is 102 p.p.m., calculated on the dry material. Draught beers average 1·5 p.p.m. and bottled beers 0·9 p.p.m. The critical copper content at which fermentation is affected appears to be between 5 and 10 p.p.m. Yeasts are examined during their progress from the culture stage with virtually no copper content, through the culture room stainless-steel plant to the brewery, where successive generations are analysed after fermentations in copper vessels. A copper content is attained which appears unlikely to be exceeded in normal circumstances; in the experiments described this approached 175 p.p.m. Trace amounts of copper are recorded for the various stages of a complete brew. From this work it appears that spent grains and spent hops have comparatively high copper contents, whilst some copper is eliminated with the first yeast heads. The difficulties of obtaining truly representative samples from large bulks, and the contribution of variable amounts of copper from the plant involved, are apparent from the results.
|
2022-12-10T08:59:29.610Z
|
15,934,716 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/LGRS.2013.2295165",
"MAG": "2081903578",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this letter, we present the results from the ground-based European Space Agency campaign TropiScat, which is aimed at evaluating the temporal coherence at P-band in a tropical forest in all polarizations and at different heights within the vegetation layers. The TropiScat equipment has been operated since October 2011 at the Paracou field station, French Guiana, to continuously produce height-range images of the forest with a temporal sampling of 15 min. The forest temporal behavior can be then captured by analyzing the interferometric coherence between the images gathered at different times, considering time scales on the order of hours, days, and months. The results indicate that the vegetation is likely to undergo a significant motion during day hours due to wind and temperature changes, whereas it appears to be definitively more stable during night hours. This result appears to provide a very useful input to the Biomass Monitoring Mission for Carbon Assessment (BIOMASS), as it suggests that the performance over a tropical forest could be optimized by gathering acquisitions in early morning or night hours. The long-term temporal decorrelation has been then evaluated by considering dawn-dawn acquisitions to minimize the impact of wind gusts and by excluding rainy days in order to not confuse forest and system decorrelation. As a result, the temporal coherence at the ground level was found to stay high at about 0.8 at 27 days, whereas the temporal coherence at the canopy height was found to be about 0.8 at 4 days and about 0.65 at 27 days, indicating coherence sensitivity to height.
|
2022-12-19T05:53:55.467Z
|
255,089,939 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3233/jae-220150",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In recent years, the necessity for inspection of the deteriorated oil-refining plant is increased. In the steel tube to be used in a heating furnace has carburizing phenomenon is the cause of the accident. As these carburizing depths increase, so does the steel tube. Therefore, inspection of these depths is important. The conductivity of the carburized layer is higher than that of the non-carburized layer in the steel tube, and it’s magnetic permeability is lower than that of the non-carburized layer. Therefore, studies are being conducted to determine the life of steel tube by applying electromagnetic non-destructive inspection electromagnetic. However, it is difficult to put it to practical use in the field because measurement error occurs due to the effect of lift-off. In this paper, we proposed an inspection method that can measure carburizing depth and lift-off at the same time. This method uses two types of search coil. One is the magnetic flux testing and the other is the eddy current testing.
|
2022-12-25T22:09:40.805Z
|
92,979,803 |
{
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"ArXiv": null,
"DOI": "10.2307/j.ctv80c9p7.23",
"MAG": "2921230546",
"PubMedCentral": null
},
"license": "CC0",
"status": "GREEN",
"url": "http://diposit.ub.edu/dspace/bitstream/2445/131580/1/577726.pdf"
}
|
B. Aubert, Y. Karyotakis, J. P. Lees, V. Poireau, E. Prencipe, X. Prudent, V. Tisserand, J. Garra Tico, E. Grauges, M. Martinelli, A. Palano, M. Pappagallo, G. Eigen, B. Stugu, L. Sun, M. Battaglia, D.N. Brown, L. T. Kerth, Yu. G. Kolomensky, G. Lynch, I. L. Osipenkov, K. Tackmann, T. Tanabe, C.M. Hawkes, N. Soni, A. T. Watson, H. Koch, T. Schroeder, D. J. Asgeirsson, B.G. Fulsom, C. Hearty, T. S. Mattison, J. A. McKenna, M. Barrett, A. Khan, A. Randle-Conde, V. E. Blinov, A.D. Bukin,* A. R. Buzykaev, V. P. Druzhinin, V. B. Golubev, A. P. Onuchin, S. I. Serednyakov, Yu. I. Skovpen, E. P. Solodov, K.Yu. Todyshev, M. Bondioli, S. Curry, I. Eschrich, D. Kirkby, A. J. Lankford, P. Lund, M. Mandelkern, E. C. Martin, D. P. Stoker, H. Atmacan, J.W. Gary, F. Liu, O. Long, G.M. Vitug, Z. Yasin, V. Sharma, C. Campagnari, T.M. Hong, D. Kovalskyi, M.A. Mazur, J. D. Richman, T.W. Beck, A.M. Eisner, C. A. Heusch, J. Kroseberg, W. S. Lockman, A. J. Martinez, T. Schalk, B.A. Schumm, A. Seiden, L. Wang, L. O. Winstrom, C. H. Cheng, D.A. Doll, B. Echenard, F. Fang, D. G. Hitlin, I. Narsky, P. Ongmongkolkul, T. Piatenko, F. C. Porter, R. Andreassen, G. Mancinelli, B. T. Meadows, K. Mishra, M.D. Sokoloff, P. C. Bloom, W. T. Ford, A. Gaz, J. F. Hirschauer, M. Nagel, U. Nauenberg, J. G. Smith, S. R. Wagner, R. Ayad, W.H. Toki, R. J. Wilson, E. Feltresi, A. Hauke, H. Jasper, T.M. Karbach, J. Merkel, A. Petzold, B. Spaan, K. Wacker, M. J. Kobel, R. Nogowski, K. R. Schubert, R. Schwierz, D. Bernard, E. Latour, M. Verderi, P. J. Clark, S. Playfer, J. E. Watson, M. Andreotti, D. Bettoni, C. Bozzi, R. Calabrese, A. Cecchi, G. Cibinetto, E. Fioravanti, P. Franchini, E. Luppi, M. Munerato, M. Negrini, A. Petrella, L. Piemontese, V. Santoro, R. Baldini-Ferroli, A. Calcaterra, R. de Sangro, G. Finocchiaro, S. Pacetti, P. Patteri, I.M. Peruzzi, M. Piccolo, M. Rama, A. Zallo, R. Contri, E. Guido, M. Lo Vetere, M. R. Monge, S. Passaggio, C. Patrignani, E. Robutti, S. Tosi, K. S. Chaisanguanthum, M. Morii, A. Adametz, J. Marks, S. Schenk, U. Uwer, F. U. Bernlochner, V. Klose, H.M. Lacker, T. Lueck, A. Volk, D. J. Bard, P. D. Dauncey, M. Tibbetts, P. K. Behera, M. J. Charles, U. Mallik, J. Cochran, H. B. Crawley, L. Dong, V. Eyges, W. T. Meyer, S. Prell, E. I. Rosenberg, A. E. Rubin, Y. Y. Gao, A. V. Gritsan, Z. J. Guo, N. Arnaud, J. Béquilleux, A. D’Orazio, M. Davier, D. Derkach, J. Firmino da Costa, G. Grosdidier, F. Le Diberder, V. Lepeltier, A.M. Lutz, B. Malaescu, S. Pruvot, P. Roudeau, M.H. Schune, J. Serrano, V. Sordini,34,x A. Stocchi, G. Wormser, D. J. Lange, D.M. Wright, I. Bingham, J. P. Burke, C. A. Chavez, J. R. Fry, E. Gabathuler, R. Gamet, D. E. Hutchcroft, D. J. Payne, C. Touramanis, A. J. Bevan, C. K. Clarke, F. Di Lodovico, R. Sacco, M. Sigamani, G. Cowan, S. Paramesvaran, A. C. Wren, D.N. Brown, C. L. Davis, A. G. Denig, M. Fritsch, W. Gradl, A. Hafner, K. E. Alwyn, D. Bailey, R. J. Barlow, G. Jackson, G.D. Lafferty, T. J. West, J. I. Yi, J. Anderson, C. Chen, A. Jawahery, D. A. Roberts, G. Simi, J.M. Tuggle, C. Dallapiccola, E. Salvati, R. Cowan, D. Dujmic, P. H. Fisher, S.W. Henderson, G. Sciolla, M. Spitznagel, R. K. Yamamoto, M. Zhao, P.M. Patel, S. H. Robertson, M. Schram, P. Biassoni, A. Lazzaro, V. Lombardo, F. Palombo, S. Stracka, L. Cremaldi, R. Godang,47,k R. Kroeger, P. Sonnek, D. J. Summers, H.W. Zhao, M. Simard, P. Taras, H. Nicholson, G. De Nardo, L. Lista, D. Monorchio, G. Onorato, C. Sciacca, G. Raven, H. L. Snoek, C. P. Jessop, K. J. Knoepfel, J.M. LoSecco, W. F. Wang, L. A. Corwin, K. Honscheid, H. Kagan, R. Kass, J. P. Morris, A.M. Rahimi, S. J. Sekula, Q.K. Wong, N. L. Blount, J. Brau, R. Frey, O. Igonkina, J. A. Kolb, M. Lu, R. Rahmat, N. B. Sinev, D. Strom, J. Strube, E. Torrence, G. Castelli, N. Gagliardi, M. Margoni, M. Morandin, M. Posocco, M. Rotondo, F. Simonetto, R. Stroili, C. Voci, P. del Amo Sanchez, E. Ben-Haim, G. R. Bonneaud, H. Briand, J. Chauveau, O. Hamon, Ph. Leruste, G. Marchiori, J. Ocariz, A. Perez, J. Prendki, S. Sitt, L. Gladney, M. Biasini, E. Manoni, C. Angelini, G. Batignani, S. Bettarini, G. Calderini,59a,59b,{ M. Carpinelli,** A. Cervelli, F. Forti, M.A. Giorgi, A. Lusiani, M. Morganti, N. Neri, E. Paoloni, G. Rizzo, J. J. Walsh, D. Lopes Pegna, C. Lu, J. Olsen, A. J. S. Smith, A. V. Telnov, F. Anulli, E. Baracchini, G. Cavoto, R. Faccini, F. Ferrarotto, F. Ferroni, M. Gaspero, P. D. Jackson, L. Li Gioi, M.A. Mazzoni, S. Morganti, G. Piredda, F. Renga, C. Voena, M. Ebert, T. Hartmann, H. Schröder, R. Waldi, T. Adye, B. Franek, E. O. Olaiya, F. F. Wilson, S. Emery, L. Esteve, G. Hamel de Monchenault, W. Kozanecki, G. Vasseur, Ch. Yèche, M. Zito, M. T. Allen, D. Aston, R. Bartoldus, J. F. Benitez, R. Cenci, J. P. Coleman, PHYSICAL REVIEW D 80, 112002 (2009)
|
2022-12-27T15:00:04.540Z
|
31,820,507 |
{
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"ArXiv": null,
"DOI": "10.2106/00004623-195941060-00002",
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},
"license": null,
"status": null,
"url": null
}
|
Alexander \ionro 52 has been credited, possibly erroneously t with being the first to report the finding of loose osteocartilaginous bodies in the ankle joint. He attributed the condition to trauma but did not classify it as a fracture. Stevenson used the same term in describing a case which he reported in 1925. In 1888 K#{246}nig43 observed loose bodies in joints other than the ankle. He referred to them as corpora mobile and speculated about their etiology. He decided that they could not have been caused by any known disease, tumor, or trauma, and concluded, without substantiating evidence, that they must have been produced by a process of spontaneous necrosis. For this hypothetical mechanism he coined the term osteochon dritis disseca n s. The first use of tile term osteochondritis thssecans as applied to the ankle joint was ma(!e i)y Kal)pis 41 in 1922. After that time the names formerly used! -loose bodies, joint mice, and corpora mobile-were used as secondary terms. Osteochondritis dissecans became the accepted name and has been used by the majority of authors since 1922. In 1932 Rendu 60 reported a case of intra-articular fragmentary fracture of the talus. The lesion, as shown l)y his roentgenograms and as described in his 01)erative note, w’as the same type that had been reported by Monro and Kappis. Rendu’s term has since been used by a few authors. Since 1932 two separate series of reports of osteocartilaginous lesions of the dome of the talus were published. In one report the lesions were called fractures, in the other they were labeled osteochondritis dissecans. When the case histories and roentgenograms in these reports were studied carefully, it became evident. that the authors of the two sets of reports were describing the same condition. In fact, in twenty-eight of the cases reported the authors used the two terms interchangeably. Because the condition rarely occurs and has been reported under many diagnostic terms, misconceptions and misunderstandings of the lesion have developed. These erroneous ideas have obscured the characteristics of the condition that are significant to the patient, the attending surgeon, and the organizations involved in compensatory payments. This report is intended to draw attention to the points of misunderstanding and to clarify them in the light of the information gained from a thorough study.
|
2023-01-01T17:37:58.265Z
|
239,496,617 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5747/ch.2018.v15.nesp2.001115",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://doi.org/10.5747/ch.2018.v15.nesp2.001115"
}
|
This paper discusses the research carried out in the field of teacher education, focusing on Early Childhood Education. Its main objective is to understand the advances in this field of research between 2000 and 2016. For this, the methodology used is part of the quantitative-qualitative approach, using as a procedure for data collection the bibliographic survey in the databases of the Caderno CEDES and ANPAE. The theoretical basis is supported by authors such as Libâneo (2001), André (2010), Saviani (2009), Nóvoa (1992), among others. Authors who help in the understanding of teacher training. The results point to quantitative advances in the field of research, at the same time, the need to advance in the field of the practice of Early Childhood Education, so that this level of education fulfills its role: to work with the potentialities of the child with a view to its development is full.
|
2022-01-24T22:57:44.299Z
|
211,035,938 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1142/s0219720019400122",
"MAG": "2990851784",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Mapping short reads to a reference genome is an essential step in many next-generation sequencing (NGS) analyses. In plants with large genomes, a large fraction of the reads can align to multiple locations of the genome with equally good alignment scores. How to map these ambiguous reads to the genome is a challenging problem with big impacts on the downstream analysis. Traditionally, the default method is to assign an ambiguous read randomly to one of the many potential locations. In this study, we explore two alternative methods that are based on the hypothesis that the possibility of an ambiguous read being generated by a location is proportional to the total number of reads produced by that location: (1) the enrichment method that assigns an ambiguous read to the location that has produced the most reads among all the potential locations, (2) the probability method that assigns an ambiguous read to a location based on a probability proportional to the number of reads the location produces. We systematically compared the performance of the proposed methods with that of the default random method. Our results showed that the enrichment method produced better results than the default random method and the probability method in the discovery of single nucleotide polymorphisms (SNPs). Not only did it produce more SNP markers, but it also produced SNP markers with better quality, which was demonstrated using multiple mainstay genomic analyses, including genome-wide association studies (GWAS), minor allele distribution, population structure, and genomic prediction.
|
2022-01-27T04:52:13.780Z
|
30,161,943 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/anie.201504835",
"MAG": "1884652893",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The funneled energy landscape theory implies that protein structures are minimally frustrated. Yet, because of the divergent demands between folding and function, regions of frustrated patterns are present at the active site of proteins. To understand the effects of such local frustration in dictating the energy landscape of proteins, here we compare the folding mechanisms of the two alternative spliced forms of a PDZ domain (PDZ2 and PDZ2as) that share a nearly identical sequence and structure, while displaying different frustration patterns. The analysis, based on the kinetic characterization of a large number of site-directed mutants, reveals that although the late stages for folding are very robust and biased by native topology, the early stages are more malleable and dominated by local frustration. The results are briefly discussed in the context of the energy-landscape theory.
|
2022-09-08T09:12:30.044Z
|
241,196,846 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1115/1.4051932",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GREEN",
"url": "https://ria.ua.pt/bitstream/10773/34306/1/TSEA-21-1316_Accepted%20Manuscript_and_cover.pdf"
}
|
An innovative methodology and a virtual test bench (VTB) are proposed to support the design of water heaters’ control strategies. This platform allows to speed up the development and evaluation of control systems even before the existence of prototypes or real test environments. By simulating the environmental conditions and the state of the different device components, it will be possible to detect and correct possible initial errors in the control system design which can be time consuming and costly due to subsequent modifications to the system or equipment components. The architecture of the proposed system establishes four operating modes: open-loop data acquisition, real-time simulation, hardware-in-the-loop simulation, and test of the complete real system, the incorporation of these functionalities in the same platform is not reported in the literature for domestic water heaters. The virtual test bench was designed to accommodate different water heaters including, but not limited to, gas, electric, and heat pumps, for instantaneous hot water production or including hot water storage. The prototype of the virtual test bench is described emphasizing the hardware-in-the-loop methodologies and embedded control. The particular case study of a tankless gas water heater (TGWH) is presented implementing the different operation modes in the virtual test bench. The water heater models, control strategies, simulation, and experimental data are presented and discussed.
|
2022-12-10T09:02:59.428Z
|
12,009,435 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1365-2125.1980.TB04921.X",
"MAG": "2112672620",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
1. Thirty pregnant women aged 22-34 yr presenting with pre-eclampsia were treated with guanfacine for periods of 16-68 days. 2. Elevated blood pressure was lowered to a statistically and clinically significantly extent in the first week of treatment, falling almost to normal levels before parturition in 24 cases. Four days after delivery all the patients had normal blood pressures. 3. Oedema (localized or generalized) was not reduced to any extent by guanfacine and additional treatment was necessary in 17 cases. There was little effect on proteinuria. 4. Twenty-five patients reported side-effects attributable to the treatment (sedation in 25 cases, dryness of the mouth in 15, and feelings of dizziness in 6 cases). 5. No notable changes were observed in either foetal or maternal heart rate during the period of treatment. Of the 30 deliveries, 19 were spontaneous, 5 by vacuum extraction, and 6 were by Caesarean section because of suspected placental insufficiency. Six of the infants were 'small-for-date babies', but all developed normally later.
|
2022-12-22T16:51:57.382Z
|
40,218,633 |
{
"externalids": {
"ACL": null,
"ArXiv": "0710.2980",
"DOI": "10.1103/PhysRevB.77.104440",
"MAG": "2103549980",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The present paper establishes characteristics of the relative magnetic permeability spectrum $\ensuremath{\mu}(f)$ of magnetic materials at microwave frequencies. The integral ${\ensuremath{\int}}_{0}^{\ensuremath{\infty}}{\ensuremath{\mu}}^{\ensuremath{''}}(f)fdf$ of the imaginary part of $\ensuremath{\mu}(f)$ multiplied with the frequency $f$ gives remarkable properties. A generalization of Snoek's law consists in this quantity being bounded by the square of the saturation magnetization multiplied with a constant. While previous results have been obtained in the case of nonconductive materials, this work is a generalization to ferromagnetic materials and ferromagnetic-based composites with significant skin effect. The influence of truncating the summation to finite upper frequencies is investigated, and estimates associated with the finite summation are provided. It is established that, in practice, the integral does not depend on the damping model under consideration. Numerical experiments are performed in the exactly solvable case of ferromagnetic thin films with uniform magnetization, and these numerical experiments are found to confirm our theoretical results. Microwave permeability measurements on soft amorphous films are reported. The relation between ${\ensuremath{\int}}_{0}^{6\phantom{\rule{0.3em}{0ex}}\mathrm{GHz}}{\ensuremath{\mu}}^{\ensuremath{''}}(f)fdf$ and $4\ensuremath{\pi}{M}_{s}$ is verified experimentally, and some practical applications of the theoretical results are introduced. The integral can be used to determine the average magnetization orientation in materials with complex configurations of the magnetization, and furthermore, to demonstrate the accuracy of microwave measurement systems. For certain applications, such as electromagnetic compatibility or radar absorbing materials, the relations established herein provide useful indications for the design of efficient materials, and simple figures of merit to compare the properties measured on various materials.
|
2022-12-31T22:34:58.515Z
|
219,022,853 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1136/bmj.m1659",
"MAG": "3019499176",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Bruce William Richards was born in Luton and raised in north London. After residency posts at St Thomas’, he spent two years’ national service in the Royal Air Force at Nuneham Courtenay and one …
|
2022-02-08T01:39:05.737Z
|
1,758,771 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4067/S0034-98872012000700009",
"MAG": "2032911646",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
BACKGROUND
Thiopurines (azathioprine and 6-mercaptopurine) are highly effective medications but with potential adverse effects. Thiopurine methyltransferase (TMPT) is the key enzyme in their pharmacokinetics and is genetically regulated. A low activity of TPMT is associated with myelotoxicity. The genotype and enzyme activity can vary by ethnicity.
AIM
To study the activity and genotype of TPMT in a group of Chilean subjects.
MATERIAL AND METHODS
In 200 healthy adult blood donors, TPMT activity was determined by high performance liquid chromatography (HPLC). Deficient, low, normal or high levels were defined when enzymatic activity was < 5, 6-24,25-55 and > 56 nmol/grHb/h, respectively. Genotyping of TPMT (*1, *2, *3A, *3B, *3C) was performed by PCR.
RESULTS
Seventy seven women (38.5%) and 123 men (61.5%), with an average age of 34.9 years were studied. Eighteen subjects (9%) had a low enzymatic activity, 178 (89%) had normal activity, 4 (2%) had high activity and no genotype deficient subjects were identified. The wild type genotype (*1) was found in 184 (92%) individuals and 16 (8%) were heterozygous for the variants: *2 (n = 2), *3A (n = 13) and *3C (n = 1). No homozygous subjects for these variants were identified. Wild type genotype had an increased enzymatic activity (40.8 ± 7.2 nmol/gHb/h) compared to heterozygous group (21.2 ± 3 nmol/ gHb/h; p < 0.001).
CONCLUSIONS
Less than 10% of a Chilean population sample has a low enzymatic activity or allelic variants in the TPMT gene, supporting the use of thiopurines according to international recommendations.
|
2022-06-12T06:52:57.012Z
|
81,343,679 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3138/JAMMI.2017-0008",
"MAG": "2891615468",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Mumps is a viral infection endemic in North America despite widespread vaccination. Typical symptoms include parotitis, fever, and myalgias; however, absence of parotitis and asymptomatic infection is common. Complications are rare, occurring in 10% or fewer of patients, and have only rarely been described since widespread adoption of the mumps vaccine. Most complications occur in non-vaccinated individuals. Myocarditis is a very rare, but clinically significant, complication of acute mumps infection. We report a case of acute myocarditis with a serological diagnosis of acute mumps infection in a previously healthy, vaccinated 24-year-old female.
|
2022-07-29T12:39:41.933Z
|
144,132,531 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3917/docsi.513.0032",
"MAG": "1991442362",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://www.cairn.info/load_pdf.php?ID_ARTICLE=DOCSI_513_0032&download=1"
}
|
[Gestion] La gestion des risques n’est plus une fonction specifique de l’entreprise. Elle est integree a toutes ses actions. Si bien que la collecte d’information, cle de l’analyse des risques, devient une mission essentielle afin de mettre a la disposition des decideurs les elements necessaires pour reduire ces risques.
|
2022-08-26T14:07:29.563Z
|
84,251,205 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1126/scitranslmed.3001252",
"MAG": "2018173371",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Activation of long-term repeat promoters restores oncogene expression and promotes survival of Hodgkin’s lymphoma.
|
2022-09-13T10:59:19.149Z
|
116,832,752 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1063/1.5008010",
"MAG": "2766889984",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Erosion damage, caused by repeated rain droplet impact on the leading edges of wind turbine blades, is a major cause for cost concern. Resin Infusion (RI) is used in wind energy blades where low weight and high mechanical performance materials are demanded. The surface coating plays a crucial role in the manufacturing and performance response. The Leading Edge coating is usually moulded, painted or sprayed onto the blade surface so adequate adhesion in the layers’ characterization through the thickness is required for mechanical performance and durability reasons. In the current work, an investigation has been directed into the resulting rain erosion durability of the coating was undertaken through a combination of mass loss testing measurements with manufacturing processing parameter variations. The adhesion and erosion is affected by the shock wave caused by the collapsing water droplet on impact. The stress waves are transmitted to the substrate, so microestructural discontinuities in coating layers and interfaces play a key role on its degradation. Standard industrial systems are based on a multilayer system, with a high number of interfaces that tend to accelerate erosion by delamination. Analytical and numerical models are commonly used to relate lifetime prediction and to identify suitable coating and composite substrate combinations and their potential stress reduction on the interface. In this research, the input parameters for the appropriate definition of the Cohesive Zone Modelling (CZM) of the coating-substrate interface are outlined by means of Pull off testing and Peeling testing results. It allowed one to optimize manufacturing and coating process for blades into a knowledge-based guidance for leading edge coating material development. It was achieved by investigating the erosion degradation process using both numerical and laboratory techniques (Pull off, Peeling and Rain Erosion Testing in a whirling arm rain erosion test facility).Erosion damage, caused by repeated rain droplet impact on the leading edges of wind turbine blades, is a major cause for cost concern. Resin Infusion (RI) is used in wind energy blades where low weight and high mechanical performance materials are demanded. The surface coating plays a crucial role in the manufacturing and performance response. The Leading Edge coating is usually moulded, painted or sprayed onto the blade surface so adequate adhesion in the layers’ characterization through the thickness is required for mechanical performance and durability reasons. In the current work, an investigation has been directed into the resulting rain erosion durability of the coating was undertaken through a combination of mass loss testing measurements with manufacturing processing parameter variations. The adhesion and erosion is affected by the shock wave caused by the collapsing water droplet on impact. The stress waves are transmitted to the substrate, so microestructural discontinuities in coating layers an...
|
2022-09-23T00:52:45.237Z
|
110,127,297 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1139/L97-016",
"MAG": "2139522348",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper describes a study of eccentrically braced framed structures to evaluate the response to seismic load. Attention is restricted to frames with shear critical links. Design procedures are first described and the designs of eight-storey structures for Canadian seismic zones 3 and 5 are obtained. A 16-storey structure for Zone 5 is also considered. The seismic response of these structures to a series of earthquake records is described. It was found that, for a number of ground motions corresponding to Zone 5, forces and deformations developed in the upper storeys of the frames exceeded those anticipated in the design process. The result of this is that some column and brace capacities in the uppermost storeys may be inadequate. A modification to the design process overcome this deficiency is proposed. This uses an iterative process incorporating the evaluation of dynamic response in the selection of members, and the resulting structures exhibit greatly improved behaviour.
|
2022-12-09T14:36:05.129Z
|
86,024,319 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1471-4159.2005.03424.x",
"MAG": "2134996692",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Although estrogens are neuroprotective in a variety of neuroprotection models, the precise underlying mechanisms are currently not well understood. Here, we examined the role of protein kinase C (PKC) in mediating estrogen‐induced neuroprotection in the HT‐22 immortalized hippocampal cell line. The neuroprotection model utilized calcein fluorescence to quantitate cell viability following glutamate insults. 17β‐Estradiol (βE2) protected HT‐22 cells when treatment was initiated before or after the glutamate insult. The inhibition of PKC by bis‐indolylmaleimide mimicked and enhanced βE2‐induced neuroprotection. In contrast, the inhibition of specific PKC isozymes (α and β) by Go6976, inhibition of 1‐phosphatidylinositol 3 kinase by wortmannin, or inhibition of protein kinase A by H‐89, did not alter cell viability, suggesting a specific involvement of PKC in an isozyme‐dependent manner. We further examined whether estrogen interacts with PKC in a PKC isozyme‐specific manner. Protein levels and activity of PKC isozymes (α, δ, ε, and ζ) were assessed by western blot analysis and radiolabeled phosphorylation assays respectively. Among the isozymes tested, βE2 altered only PKCε; it reduced the activity and membrane translocation of PKCε in a manner that correlated with its protection against glutamate toxicity. Furthermore, βE2 reversed the increased activity of membrane PKCε induced by glutamate. These data suggest that the neuroprotective effects of estrogens are mediated in part by inhibition of PKCε activity and membrane translocation.
|
2022-12-19T03:00:59.785Z
|
231,885,682 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1101/2021.02.04.429837",
"MAG": "3155231577",
"PubMedCentral": "8056616"
},
"license": null,
"status": "GREEN",
"url": "https://www.biorxiv.org/content/biorxiv/early/2021/02/26/2021.02.04.429837.full.pdf"
}
|
Background Gene annotation in eukaryotes is a non-trivial task that requires meticulous analysis of accumulated transcript data. Challenges include transcriptionally active regions of the genome that contain overlapping genes, genes that produce numerous transcripts, transposable elements and numerous diverse sequence repeats. Currently available gene annotation software applications depend on pre-constructed full-length gene sequence assemblies which are not guaranteed to be error-free. The origins of these sequences are often uncertain, making it difficult to identify and rectify errors in them. This hinders the creation of an accurate and holistic representation of the transcriptomic landscape across multiple tissue types and experimental conditions. Therefore, to gauge the extent of diversity in gene structures, a comprehensive analysis of genome-wide expression data is imperative. Results We present FINDER, a fully automated computational tool that optimizes the entire process of annotating genes and transcript structures. Unlike current state-of-the-art pipelines, FINDER automates the RNA-Seq pre-processing step by working directly with raw sequence reads and optimizes gene prediction from BRAKER2 by supplementing these reads with associated proteins. The FINDER pipeline (1) reports transcripts and recognizes genes that are expressed under specific conditions, (2) generates all possible alternatively spliced transcripts from expressed RNA-Seq data, (3) analyzes read coverage patterns to modify existing transcript models and create new ones, and (4) scores genes as high- or low-confidence based on the available evidence across multiple datasets. We demonstrate the ability of FINDER to automatically annotate a diverse pool of genomes from eight species. Conclusions FINDER takes a completely automated approach to annotate genes directly from raw expression data. It is capable of processing eukaryotic genomes of all sizes and requires no manual supervision—ideal for bench researchers with limited experience in handling computational tools.
|
2022-12-17T21:00:18.633Z
|
74,630,164 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1051/PMED:2008332",
"MAG": "2185693556",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Context: Dissections in laboratory of anatomy are always the object of specific reactions before, during or after exposure with a cadaver. Aim: To better understand, in a comparative manner, what arises in young 2nd year medical students, who are often virgin of any death experience, with nurse students specialized in the operating room, who have in addition to their personal experience, a professional experience. Method: Two focus groups exploring the same dimensions, one including 12 2nd year medical students and the other comprising 12 operating room nurse students. Results: The nurse students express more
|
2022-01-28T15:30:38.552Z
|
11,994,701 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICDRET.2014.6861712",
"MAG": "2053697770",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A serpentine type thermosyphon flat-plate solar water heater has been constructed and fabricated with locally available material. The hourly system performance of the solar water heater has been experimentally investigated for several days in Dhaka city (lat 23.7° N, long 90.38° E) of Bangladesh. The single glazed collector was made from copper sheet and tubes. The collector was tilted at an angle of 27 degree facing south on a supporting structure. The working fluid of the closed thermosyphon heated at the serpentine type flat-plate collector enters the water tank due to density gradient caused by temperature differences. Such collectors are adequate for water heating and this at present is an economical way to use solar energy for water heating. In performance evaluation of the serpentine type solar water heater, inlet and outlet water temperature of collector and tank water temperature was recorded for consecutive hours. Maximum collector outlet water temperature obtained was 67°C and maximum tank water temperature obtained was 61°C during June-July period. From the collected data, various temperature graphs are plotted and analyzed for different solar time, various amount solar insolation and different weather condition. A pH test was also carried out to study the pH value of water within the aluminium built water tank. Some recommendations are made after evaluating the performance of thermosyphon, thermal insulation of water tank, collector radiation absorption, effects of glazing and losses of the collector. This is a field level experiment to improve the device performance and cost reduction for the construction. Conclusion can be drawn after evaluating the performance over a certain period of time for different designs and modifications.
|
2022-02-13T04:51:30.105Z
|
248,820,813 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S0017089500030536",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
As in [3] let {a, b}designate the Pythagorean ratio (a2 − b2)/2ab between the sides of a rational right angled triangle. The principal result of [3] is that {a, b}is the arithmetic mean of two Pythagorean ratios, and hence is the middle term of a three term arithmetic progression, if and only if a /b is the geometric mean of two Pythagorean ratios. Here in Part II we study sets of four Pythagorean ratios in arithmetic progression. We show that sets of four in consecutive places in an arithmetic progression are closely related to sets of four in the first, second, third and fifth places in a progression; any one of the former sets determines two of the latter sets, and either one of the latter sets determines the other and the former. We construct an infinite sequence of sets of four ratios in consecutive places of arithmetic progressions, the last term of each set being the first term of the next set. These sets are related to solutions of the Diophantine equations r2 = 5p2q2 ± 4(p4 − 2q4). Computer searches, in addition to exhibiting enough members of this sequence to enable us to identify it, also exhibited two sets which do not belong to this sequence.
|
2022-08-10T21:51:09.275Z
|
190,525,412 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.32936/PSSJ.V2I3.60",
"MAG": "2947595387",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The process of urbanization in developing nations is attended without fast industrialization processes. As a result of this, the urbanization and urban process are accompanied by diverse problems. Hence this paper is aimed at identifying the effect of urbanization on citizens’ food insecurity by monitoring agricultural foodstuff production as a mediating variable. A quantitative research methodology or approach has been used to depict out urban problems associated with unmanaged urbanization in the Ethiopian, particularly in Amhara regional state. Structural Equation Modeling was employed to run a mediation analysis by decomposing the direct and indirect effects of one variable on the other. Correlation and regression analyses were executed to measure the direction and magnitude of the effect of the independent variable on the dependent. Regression analysis results indicated the existence of a significant direct effect of urbanization on food insecurity of citizens. The mediation analysis result shows agricultural foodstuff production doesn’t play a mediating role between urbanization and food insecurity. The paper, having traced out the effect of the urbanization on food insecurity, provides possible recommendations. The regional government should be very considerate about the pace of unmanaged, unindustrialized and unemployment induced urbanization. The regional government should address all pushing factors that are dragging farmers into the urban areas. So, it is important to find ways to make farmers beneficial from their farm activities. In this regard, the problem raised by farmers is the inability to settle the debt from fertilizers and improved seeds or at least what they get from selling what they have produced is used to settle their farm debt. Some policy measures such as subsidizing the farmer or extending the repayment period of their debt are then essential to help farmers lead a stable life and lead their families. The government/concerned body need to make a cost-benefit analysis by weighing the pressure from the migration of the farmers and the cost of subsidizing the farmers: compare prevention with curative. Moreover, as a short-term solution, the regional government should identify food unsecured urban households and embrace them in food security packages like urban safety-net programs. And enhancing the limited income generation capacity of food insecured households.
Key words: Urbanization, Food in Security, Agricultural Foodstuff Production, Amhara Region
|
2022-09-02T04:13:02.060Z
|
28,019,692 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1259/0007-1285-27-318-318",
"MAG": "2156565614",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A new method of ascending venography of the lower limb and pelvis is described, in which the contrast medium is injected into the medulla of an appropriate bone. The path taken by the contrast medium is indicated. The scope and value of the method and its advantages are illustrated by reference to cases of acute deep thrombophlebitis, gravitational ulceration and skin diseases. Intraosseous venography has proved to be a safe, simple, flexible, and certain method of demonstrating the deep, superficial and communicating veins of the leg and pelvis. It is quickly carried out under local or short Pentothal anaesthesia and is thus suitable as an outpatient examination. Both legs may be investigated at a single session, using 20 c.c. of 50 per cent Uriodone for each leg. The examination may be completed in five minutes. Thirty patients have been investigated in the past four months without incident.
|
2022-09-14T13:20:53.590Z
|
227,008,041 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3760/CMA.J.ISSN.1001-4497.2014.10.001",
"MAG": "3032409010",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Objective To retrospectively analyze the early and medium-term effect of the primary application of the sutureless repair to infant patients with total anomalous pulmonary venous connection (TAPVC).Methods One hundred and twenty-six consecutive infants(July 2007 to December 2012) with supracardiac,infracardiac and mixed-type TAPVC were retrospectively reviewed and followed up till April 2013.Survival and postoperative pulmonary venous obstruction (PVO) were compared between the sutureless group (54 cases ; median age 60 days ; body weight 4.2 kg) and the conventional group (72 cases ; median age 30 days; body weight 4.2 kg).Predictors for death and PVO were identified by an univariate and multivariate analysis using a Cox logistic method.Results No differences were noted on preoperative variables between the groups.The cardiopulmonary bypass time and aortic crossclamp time are much shorter in the sutureless group than the conventional group (83.5 min vs.100.0 min,Z =1 296.000,P =0.001 ; and 43.0 min vs.57.0 min,Z =1181.500,P =0.000,respectively).Two patients in the sutureless group and eight in the conventional group died in hospital.There was a trend toward lower in-hospital death rate in the suturelss group(3.7 ％ vs.11.1％,x2 =1.414,P =0.234).Furthermore,the rate of total death(5.6％ vs.23.6％,x2 =7.533,P=0.006) and PVO(1.9 ％ vs.16.7％,x2 =7.319,P=0.007) is decreased in the sutureless group.Adjusted by the factors of preoperative PVO,mixed-type,neonates and body weight,the conventional surgical technique is significantly related to postoperative death [HR =4.53,95 ％ CI(1.31,15.72),P =0.017] and PVO [HR =10.42,95％ CI(1.32,82.02),P =0.026].Conclusion Results Conclusions The primary sutureless repair for the patients with TAPVC appeared to be safe and effective,resulting in improved survival and freedom from PVO and reintervention.
Key words:
Heart disease, congenital; Cardiac surgical procedures; Total anomalous pulmonary venous connection ; Sutureless technique
|
2022-10-07T13:50:52.760Z
|
25,775,945 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1468-2850.2010.01224.X",
"MAG": "2104558332",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
[Clin Psychol Sci Prac 17: 327–336, 2010]
Among boys, about one-third who exhibit severe attention-deficit/hyperactivity disorder (ADHD) in preschool follow a developmental trajectory to early-onset conduct disorder (CD) in later childhood and adolescence. Moreover, the vast majority of adolescent boys with early-onset CD also meet criteria for ADHD. Although trait impulsivity, a predisposing vulnerability to both ADHD and CD, is about 80% heritable, environmental risk factors play an important role in how impulsivity is expressed, including whether young children with ADHD eventually develop CD. In this article, we (a) describe how environmental risk potentiates early-onset conduct problems among trait-impulsive and therefore vulnerable individuals and (b) outline implications for conceptualizations of externalizing comorbidity. Although other pathways to CD exist, we focus on what is likely to be a common developmental trajectory to this costly psychiatric condition.
|
2022-12-19T19:41:17.623Z
|
210,316,454 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/11035897.2019.1655789",
"MAG": "2978027446",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
ABSTRACT The Alpha Ridge-Mendeleev Rise (AMR) is the major bathymetric feature in the Amerasia Basin of the Arctic Ocean. Its tectonic history is controversial due to its remote location in ice covered waters making data acquisition difficult, resulting in the lack of diagnostic data. Analysis of the wide-angle reflection/refraction data based on the compressional waves (P-waves) from the AMR indicates that its velocity/depth structure is typical of large igneous provinces (LIPs). LIPs can form on either oceanic or continental crust and can exhibit complex history of development. Here converted shear waves (S-wave) on the Alpha Ridge have been used to calculate Poisson’s ratios and many of measured values are within the felsic range in the upper crust. They are comparable to published S-waves from the Mendeleev Rise. They are also consistent with the results of Rayleigh-wave group-velocity analysis that indicate the Alpha Ridge in adjacent northern Canada has an intermediate composition. Based on magnetics, pseudogravity and volumetric considerations the High Arctic Large Igneous Province (HALIP) most closely resembles the Kerguelen Plateau, a LIP with a continental component. The geophysical characteristics of the AMR are compatible with a number of other LIPs that have continental affinities. A variety of offshore information from dredges and cores and onshore geological data support continental fragments incorporated in the AMR.
|
2022-12-20T16:49:26.180Z
|
15,786,042 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1145/1113361.1113372",
"MAG": "2049997296",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Routing overlays have become a viable approach to working around slow BGP convergence and sub-optimal path selection, as well as to deploy novel forwarding architectures. A common sub-component of a routing overlay is a routing mesh: the route-selection algorithm considers only those virtual links inter-node links in an overlay---in the routing mesh rather than all N2 virtual links connecting an N-node overlay. Doing so reduces routing overhead, thereby improving the scalability of the overlay, as long as the process of constructing the mesh doesn't itself introduce overhead.This paper proposes and evaluates a low-cost approach to building a topology-aware routing mesh that eliminates virtual links that contain duplicate physical segments in the underlying network. An evaluation of our method on PlanetLab shows that a conservative link pruning algorithm reduces routing overhead by a factor of two without negatively impacting route selection. Additional analysis quanti es the impact on route selection of defining an even sparser mesh on top of the topology-aware routing mesh, documenting the cost/benefit tradeoff that is intrinsic to routing. It also shows that constructing a sparser routing mesh on the topology-aware routing mesh---rather than directly on the Internet---itself benefit,; from having the reduced number of duplicate physical segments in the underlying network, which improves the resilience of the resulting routing mesh.
|
2022-12-31T19:15:42.275Z
|
110,959,774 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1049/EP.1965.0227",
"MAG": "2140728019",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Increased interest in accelerometers has been one of the by-products of inertial-guidance studies. This survey of the accelerometer field sketches the basic theory on which the instruments are based, and explains the different categories into which they are divided.
|
2022-02-10T04:36:23.036Z
|
81,969,154 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/039156036603300209",
"MAG": "2897998918",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The remarkable number of the Authors who answered, and their great competence, emphasize the importance of this inquiry. It was easy to foretell that not all the Authors, who received the questionnaire, would have answered with perfect adherence to the queries, as the subject is, in some way, out of the daily practice and a little mysterious. Infact some Authors, who participated in the « symposium », admitted many uncertainties, as well as uncertainties on the subject are met in the current bibliography. Therefore MARSHALL, LATTIMER, STEWART, HIGGINS, WINCQZ, NEDELEC, MIDANA and others, praise OBELHOR'S initiative and hope that by the mutual work fruitful results will be reached. We hope that those outstanding scientists will not be completely deceived, as the inquiry has pointed out many sides of this polyhedral problem, even if many other sides have not been evidenced. As R. OBELHOR is dealing with the summary of the answers which refer to the chief subject of the inquiry, (i.e. the most fitted therapy concerning the induratio penis plastica I.p.p.), I shall discuss the general clinic. I will also try to evaluate the 110 answers with the aim to reach a better knowledge concerning the etiopathology of I.p.p. and the other collagenous associations which often join this condition and which I suggested to assemble into a unic symptomatological entity. The remarkable number of observations, referring to more than 3500 cases of Lp.p., gives me the possibility, I think, if numbers are of importance in statistics -.:.. to deduce some definitive conclusions.
|
2022-09-10T15:31:48.368Z
|
30,575,949 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2478/s11756-009-0053-3",
"MAG": "2045132115",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
Bombyx mori nucleopolyhedrovirus (BmNPV) orf4 has been shown to be expressed at very early stage of Bm-NPV infection cycle. In this study, using transient expression experiment, we demonstrated for the first time that orf4 promoter is an immediate early promoter, indicating that orf4 may play a role in the immediate-early stage of BmNPV infection. Moreover, with the recently developed Bac-to-Bac/BmNPV baculovirus expression system and a modified pFast-Bac1 whose polyhedrin promoter was replaced with orf4 promoter, a recombinant bacmid baculovirus expressing enhanced green fluorescent protein (EGFP) under the control of orf4 promoter in Bombyx mori (Bm) cells was successfully constructed. The result not only showed that the polyhedrin promoter can be replaced easily with other promoters to direct the expression of foreign genes by using this novel system but also laid the foundation for the rescue experiment of orf4 deletion mutant.
|
2022-12-20T01:05:49.356Z
|
152,228,441 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/20403313.2017.1296072",
"MAG": "2598990914",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In Allowing for Exceptions, Luis Duarte d’Almeida offers an ambitious and instructive account of what it is for a fact to be an exception to a rule. His arguments are rigorous and clear, and his discussions of existing views on the issue are thorough and insightful. The book is a must-read for legal philosophers working on the topic of exceptions and legal reasoning. In its choice of subject matter, the book does not aim to influence legal practitioners in their day-to-day work. Nor does Duarte d’Almeida argue for or against particular doctrinal reforms. The reason for this, as Duarte d’Almeida himself notes, is that his ‘main concern throughout this book [is] descriptive, not normative’ (266). His aim is to elucidate the very concept of an exception to a rule, and not to say anything ‘about which facts ought to be classified as exceptions, and which ought not to be’ (266). His purpose thus is not to give a substantive theory of exceptions, but rather, we might say, a meta-theory thereof. The point of the exercise is to help understand how exceptions function in general, not necessarily to generate reasons for altering or preserving the content of any particular body of law.
|
2022-02-09T02:59:15.830Z
|
53,463,957 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ISGTEurope.2018.8571604",
"MAG": "2905336940",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Control systems rely on correct causal ordering and typically also on exact times and time relationships between events. For non-trivial systems, this implies synchronisation between distributed components, potentially from sensors and actuators to SCADA hierarchies. Whilst this can be accomplished by point-to-point synchronisation against a common reference such as GNSS (global navigation satellite) signals, common practice and codification in the ISO/IEC 60870-5-104 protocol widely used in the power control domain calls for the Network Time Protocol (NTP). In this paper we therefore describe attack patterns allowing the undetected partial re-play of legitimate messages and injection of messages even in the presence of ISO/IEC 62351 protective measures in a multi-staged attack targeting time synchronisation protocols and specifically the NTP protocol, and resulting in a de-synchronisation between a PLC/RTU and higher-level SCADA components. We demonstrate the feasibility of such attacks in a co-emulation environment.
|
2022-01-27T16:13:16.073Z
|
156,676,603 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.7202/005090AR",
"MAG": "1483036334",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Avec la montee de l'instabilite conjugale, un pourcentage croissant de peres sont appeles a connaitre des modifications de leur role parental. L'eclatement de la premiere famille qu'ils ont fondee ne constitue bien souvent que le debut d'une serie de transitions a venir. En formant une nouvelle union, par exemple, un homme quittera bien souvent le statut de pere seul qu'il occupait a temps partiel pour prendre celui de beau-pere a plein temps aupres des enfants de sa conjointe; il pourra ainsi cumuler plusieurs roles, comme pere des enfants nes d'une premiere union, comme beau-pere des enfants de sa conjointe, voire comme pere d'un nouvel enfant issu de la recomposition familiale. De quels enfants cet homme est-il responsable ? Et quels enfants a-t-il l'obligation de «nourrir» ? Pour tenter de repondre a ces questions, cet article s'attache d'abord a documenter d'un point de vue demographique les trajectoires parentales des hommes. On examinera ensuite certaines des politiques mises de l'avant au Quebec, au Canada et dans certains Etats americains pour regler les differents aspects de la prise en charge des enfants par suite d'une rupture d'union, et on tentera d'evaluer la pertinence des mesures preconisees, compte tenu de la diversification des trajectoires paternelles
|
2022-07-31T06:19:38.111Z
|
125,848,146 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/WCT.2003.1321518",
"MAG": "2545192988",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper investigates the radiation characteristics of a new type of array that is based on the family of space-filling and self-avoiding fractals known as Peano-Gosper curves. The elements of the fractal array are uniformly distributed along a Peano-Gosper curve, which leads to a planar array configuration with parallelogram cells that is bounded by a closed Koch curve. These unique properties are exploited in order to develop a design methodology for deterministic arrays that have no grating lobes even when the minimum spacing between elements is increased to at least one-wavelength. This leads to a class of arrays that are relatively broadband when compared to more conventional periodic planar arrays with square or rectangular cells and regular boundary contours. An efficient iterative procedure for calculating the radiation patterns of these Peano-Gosper fractal arrays to arbitrary stage of growth P are also presented.
|
2022-09-05T22:22:02.965Z
|
4,773,398 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1534/genetics.117.203059",
"MAG": "2621605644",
"PubMedCentral": "5499170"
},
"license": "CCBY",
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc5499170?pdf=render"
}
|
Within quantitative genetics, the term “epistasis” is used to broadly describe situations in which combinations of genetic variants show nonadditive phenotypic effects ([Phillips 1998][1], [2008][2]; [Mackay 2014][3]). Although most work on epistasis has focused on pairs of variants that
|
2022-12-04T07:06:10.087Z
|
45,860,930 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4158/EP-2017-0057",
"MAG": "2768944089",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
OBJECTIVE
Pheochromocytomas and paragangliomas (PPGLs) are neuroendocrine tumors derived from adrenal or extra-adrenal locations, respectively. Upon suspicion of PPGL, specific metabolomic, molecular, biochemical, imaging, and histopathologic studies are performed to prove, localize, treat, and monitor disease progression. Improved diagnostic tools allow physicians to accurately diagnose PPGL, even in patients presenting with small (<1 cm) or biochemically silent tumors, which previously delayed proper detection and treatment.
METHODS
This review outlines the most updated approach to PPGL patients and presents a new diagnostic protocol for physicians to increase earlier tumor identification and accurately assess metastatic behavior.
CONCLUSION
We present the most recent advances in genetics, epigenetics, metabolomics, biochemical, and imaging diagnoses of this rare tumor to properly assess disease, decide treatment options, and manage follow-up. We also elaborate on new therapeutic perspectives in these very rare neoplastic entities.
ABBREVIATIONS
ATRX = ATRX chromatin remodeler; ccRCC = clear cell renal cell carcinoma; c-MYC = MYC proto oncognene; CT = computed tomography; DOTATATE = DOTA-octreotate; EGLN1/2 = egl-9 family hypoxia inducible factor 1/2; EGLN2/PHD1 = egl-9 family hypoxia inducible factor 2; EPAS1/HIF2A = endothelial PAS domain protein 2/hypoxia-inducible factor 2α; ERK = extracellular signal-regulated kinase; HIFs = hypoxia-inducible factors; HIF-α = hypoxia-inducible factor alpha; HNPGLs = head and neck paragangliomas; 177Lu-DOTATATE = lutetium octreotate; MAX = myc-associated factor X; MDH2 = malate dehydrogenase; MIBG = metaiodobenzylguanidine; MN = metanephrine; MRI = magnetic resonance imaging; mTOR = mammalian target of rapamycin; NETs = neuroendocrine tumors; NF1 = neurofibromin 1; NMN = normetanephrine; PHD = prolyl hydroxylase domain protein; PI3K = phosphoinositide 3-kinase; PPGLs = pheochromocytoma and paragangliomas; PRRT = peptide receptor radionuclide therapy; Pvhl = von Hippel-Lindau protein; RAS = rat sarcoma oncogene; RET = rearranged during transfection proto-oncogene; SDH = succinate dehydrogenase; SDHA, -B, -C, -D = succinate dehydrogenase subunits A, B, C, D; SDHAF2 = succinate dehydrogenase complex assembly factor 2; SDHB, C, D = succinate dehydrogenase subunits B, C, D; SDHx = succinate dehydrogenase subunits; SSTRs = somatostatin receptors; VHL = von Hippel-Lindau.
|
2022-12-10T09:37:07.642Z
|
251,745,618 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3389/fpsyg.2022.949673",
"MAG": null,
"PubMedCentral": "9443839"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.frontiersin.org/articles/10.3389/fpsyg.2022.949673/pdf"
}
|
The notion of teacher identity has gained momentum in second language (L2) teacher education in the past decade. However, the research into Chinese as a Foreign Language (CFL) teacher identity has yet to receive more attention. The study employed a narrative inquiry to explore a native Chinese CFL in-service teacher’s identity negotiation and transformation within an international teacher education program. Self-reported narrative accounts, including multiple in-depth interviews and once-a-term reflective journals, were complemented by field notes and program documents. This data captured how the participant teacher negotiated internally with self and externally with the new environment to pursue professional growth. Mezirow’s transformative learning theory was used to reveal the cognitive trajectory of the participant’s teacher identity transformation with critical reflection as the central stage. Further, guided by Eteläpelto et al.’s framework of professional agency, the study also unraveled multiple external and internal influences on the transformational trajectory. The findings confirmed the value of integrating these two theoretical perspectives to explore language teacher identity development and offer insights into L2 teacher education practices focusing on teacher identity development.
|
2022-12-16T21:43:37.616Z
|
108,446,059 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2118/0599-0047-JPT",
"MAG": "2003113275",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A method has been developed to expand the diameter of solid tubulars downhole. This technology provides cost-effective solutions to several tubular problems that have presented obstacles to comprehensive reservoir exploitation. Operators can use smaller holes to drill deeper vertical wells or to extend the reach of deviated wells to access untapped reservoirs. In older fields, existing well-bores can be repaired with expanded tubulars or their tubular strength and integrity can be increased.
|
2022-12-20T08:19:35.308Z
|
243,523,282 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.17165/tp.2020.3-4.24",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A sajátos nevelési igényű óvodás gyerekek száma az elmúlt években folyamatosan emelkedő tendenciát mutatott. Ezzel párhuzamosan, nőtt a többségi intézményekben integráltan neveltek száma is (KSH oktatási adatok). Mindezek következtében egyre központibb szakmai kérdéssé válik a sikeres együttnevelés, melynek egyik legmeghatározóbb szubjektív feltétele, a befogadó többségi pedagógus, valamint az intézmény viszonyulása az integrációhoz (Csányi, 2000). Ennek okán kutatásomban, összefüggéseket keresve, többek között vizsgálom, hogyan vélekednek 2020-ban Magyarországon az óvodapedagógusok az integrált nevelésről és az arra felkészítő óvodapedagógusképzésről. Az eredmények alapján elmondható, hogy az anonim kérdőívet kitöltők 72%-ának okoz nehézséget az SNI gyerekek mindennapi óvodai nevelése. A 163 válasz pontbiszeriális korreláció vizsgálat alapján nem fedezhető fel összefüggés a pályán eltöltött évek és a között, mennyire jelent nehézséget az SNI gyerekek ellátása. A válaszok azt mutatják, hogy a legnagyobb nehézséget az autizmus spektrum zavarral élő gyerekek integrálása jelenti a kollégáknak.
|
2022-02-07T20:10:44.118Z
|
159,792,987 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.21697/ZP.2010.10.1.05",
"MAG": "2582073994",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The Term ‘Pirate’ in Cicero’s Works – Invective or More? Summary Being a remarkably acute politician, Cicero was aware of the fact that in order to discredit his opponents he had to appeal to his audience’s deepest fears. That is why he called his enemies pirates – the Romans were affraid of maritime bandits who constituted a significant threat at the Mediterranean. In his early speeches, such as Pro Roscio , Cicero used the term ‘pirate’ as an invective. In the Verrine orations piracy was one of the basic topics: Verres himself was called pirate but he was also accused of tollerating piracy and taking bribes from pirate leaders. Cicero’s most bitter enemy Clodius was called pirate in order to show that his tribunate was illegal. It was the first time when piracy was used not only as an invective but as a part of legal reasoning. It was based on Cicero’s theory that pirates were common enemies of all mankind fully expressed in the treaty De officiis . Campaingning for the last time in his life against Antonius Cicero called him an archpirate thus giving Octavian a possibility to impunely break all the agreements with him, because only oaths given to war enemies were binding whereas those given to pirates were not sanctioned by the law of war.
|
2022-02-08T23:04:12.860Z
|
83,798,961 |
{
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"ArXiv": null,
"DOI": "10.3181/00379727-39-10159",
"MAG": "1965185119",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Conclusions 1. In the early gastrula of the anuran Hyla regilla the inductor of the neural plate is localized approximately in the dorsal lip region of the mesodermal band, that is, it extends about 45° on either side of the dorsal mid-line. 2. The tail-forming potencies are localized in the lateral and ventro-lateral regions of the mesoderm, with the higher percentage of tails developing from the ventro-lateral regions after implantation. The dorsal and the ventral lip mesoderm do not form tails after implantation. 3. The present results show that the anuran Hyla has distinct differences in the localization of certain developmental capacities as compared to the eggs of urodeles. Both the neural inductor and the tail mesoderm have a more limited meridional extent in Hyla.
|
2022-02-11T01:12:19.829Z
|
14,933,197 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.22038/IJORL.2016.6537",
"MAG": "2293393508",
"PubMedCentral": "4881879"
},
"license": null,
"status": null,
"url": null
}
|
Introduction: Emotional words in comparison with neutral words have different hemispheric specialization. It is assumed that the right hemisphere has a role in processing every kind of emotional word. The objective of the present study was the development of a Persian version of the dichotic emotional word test and evaluate its validation among adult Persian speakers. Materials and Methods: The present study was done on 60 adults, with the age ranging from 18-30 years for both genders, who had no history of neurological disorders with normal hearing. The developed test included eight main lists; each had several dichotic emotional/ neutral pairs of words. Participants were asked to recall as many words in each list as they could after they listened to them. A content validity index was used to analyze the validity of the test. Results: The mean content validity index score was 0.94. The findings showed that in the left ear, emotional words were remembered more than neutral ones (P=0.007). While in the right ear, neutral words were remembered more (P=0.009). There were no significant differences in male and female scores. Conclusion: Dichotic emotional word test has a high content validity. The ability to remember emotional words better in the left ear supports the dominant role of the right hemisphere in emotional word perception.
|
2022-02-13T02:21:39.622Z
|
125,650,376 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/030641909702500103",
"MAG": "2732425369",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The teaching of power cycles in courses of thermodynamics or thermal engineering was traditionally based on first-law analysis. Second-law analysis was typically taught later, and not integrated with it. This approach leaves the student ignorant of the effect of operating parameters and cycle modifications on the accompanying exergy (availability) magnitudes and component irreversibilities, which are necessary for evaluating the potential for further system improvements. It also leaves many of the students with an ambiguous understanding of the exergy concept and its use. Consonant with the gradual changes in this educational approach, which increasingly attempt to integrate first- and second-law analysis, this paper recommends a strategy which integrates exergy analysis into the introduction and teaching of energy systems, demonstrated and made didactically appealing by an examination of the historical evolution of power plants, emphasizing the objectives for improvements, accomplishments, constraints, and consequently the remaining opportunities. Important conclusions from exergy analysis, not obtainable from the conventional energy analysis, were emphasized. It was found that this approach evoked the intellectual curiosity of students and increased their interest in the course.
|
2022-03-29T07:12:31.926Z
|
207,645,489 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1161/CIRCRESAHA.112.279398",
"MAG": "2134271002",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
From the time of their initial isolation, scientists have been fascinated by one particular characteristic of pluripotent stem cells: their ability to differentiate into specific cell types. Initially, this property was exploited to explore the changes in gene expression that accompany cell fate choices, and a vast amount of knowledge was added to the developmental biology literature, based both on in vitro studies and the generation of mice with specific alterations in crucial loci. With the advent of human embryonic stem cells (ESCs), an additional possibility arose: the chance that these cells might be the source of a new type of therapy, one in which absent or diseased cells were replaced by healthy versions derived from human ESCs. Cardiovascular disease presented an appealing target; the shortage of donor hearts, coupled with the tantalizing possibility of generating unlimited supplies of new myocytes, attracted a great deal of attention.
Article, see p 1286
Of course, there were always other possible candidate cells to be used in this type of therapy. Skeletal myoblasts,1 which are readily obtainable from both allogeneic and autologous sources, as well as cells isolated from the bone marrow,2 bone marrow stroma,3 and other tissue sources,4 were evaluated as possible therapeutic cells. In many cases, these cells were isolated and injected into various types of preclinical models of heart damage with the hope that something about the damaged heart environment would trigger a fundamental change in the nature of the input cells. In fact, in many cases, the injected cells quickly vanished from the injected animals, likely because of immune rejection or the simple stress of transplantation. The observed impermanence of these transplanted cells created a puzzle: why did so many of these cells actually improve heart function …
|
2022-08-19T10:18:21.504Z
|
93,813,282 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1081/SCC-120002010",
"MAG": "1982631573",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
ABSTRACT A convenient route for the synthesis of new variety of pyrazolo[1,5-a]pyrimidine derivatives by the reaction of 5-aminopyrazoles with suitable unsaturated keto compounds. The structure of the reaction products were established based on the elemental analysis, spectral data (IR, 1H NMR, MS) and X-ray diffraction analysis.
|
2022-09-13T00:22:03.513Z
|
71,934,987 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1001/JAMA.1940.02810190001001",
"MAG": "2022672545",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The unfortunate controversy over the relative merits of immediate and delayed operation for advanced appendicitis can be settled only by results obtained with one or the other method of treatment. Reports on these results will be misleading if they cover cases not really advanced, for these will decrease the relative number of deaths following either method of treatment. Reports in which the cases are vaguely described as "late" or "with spreading peritonitis" are not convincing. The mere diagnosis of appendicitis, especially in a child, is often difficult, and the diagnosis before operation of the actual stage of the disease is usually impossible. The duration of the disease is no measure of its gravity, nor are the laboratory observations. The discoveries made by physical examination, especially of children, are hard to interpret. Even at operation the surgeon cannot estimate the extent of the peritonitis without, as Ladd says, "he does a
|
2022-11-15T22:32:51.930Z
|
154,553,299 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1086/255040",
"MAG": "2053072690",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
T r aHE development of negotiable commercial paper in the seventeenth century marks the end of the "primitive" stage of deposit banking. Earlier bankers, unable to discount bills so as to spread the risk of their loans over a multitude of mercantile operations, were lured into overambitious ventures. They held a volume of deposits which enabled them, in ordinary times, to satisfy their depositors without keeping all their funds on hand in cash. But their efforts to draw profits from the money intrusted to them led to direct participation in commercial undertakings and loans to princes. Such firms as the Bardi of Florence or the Welsers of Augsburg touched dazzling profits, grew bolder, and, engaging their depositors' funds yet more deeply in government loans or speculations in commodities, ended in sensational failures. The well-known stories of such international bankers leave the impression that the great dangers of bank failure in that early stage of deposit banking came from the two sources named -commercial speculation and loans to princes. The international bankers supplied the needs of some centers; those of other cities were met by local banks. The latter were sometimes profit-seeking ventures of private bankers, sometimes public institutions subject to the city government. Although the municipal banks of Barcelona (I400) and Valencia (I407) have sometimes been confused with giro banks, on the assumption that they merely transferred payments on their books and did not make loans, this is a mistake. Giro banks did not come into existence until the late sixteenth century, at Venice in i584 and at Amsterdam in i609. It is true, however, that the chief function assumed later by the giro banks had been performed earlier by the public or private local banks. Through the transfers of deposits
|
2022-12-03T19:56:37.764Z
|
22,113,527 |
{
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"ArXiv": null,
"DOI": "10.1021/JP052210+",
"MAG": "1999237689",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We report on the characterization of an isomorphously substituted Fe-MCM-22 sample containing both Fe and Al in framework positions (Si/Fe = 44, Si/Al = 25). XANES spectroscopy was used to study the evolution of Fe sites as a consequence of thermal activation at high temperature (1073 K) and subsequent oxidation with N2O. The results were compared to those obtained in the same conditions on a well-known Fe-silicalite sample (Si/Fe = 68, Si/Al = infinity). In both samples, thermal activation causes migration of a fraction of Fe ions from framework to extraframework positions, this migration being accompanied by a reduction of Fe3+ to Fe2+. Upon oxidation with N2O at 523 K, the two samples show a different behavior. While in Fe-silicalite practically all of the Fe2+ sites formed by thermal activation are reoxidized to Fe3+, in Fe-MCM-22 only a fraction of the extraframework iron sites is involved in the reoxidation process. The accessibility of the extraframework Fe sites was also investigated by using the NO molecule as a surface probe. Upon NO dosage on the sample, the modification of the pre-edge peak and of the edge position suggests an important charge release from the extraframework Fe2+ ions to the adsorbed molecules. This could be formalized with the formation of Fe3+(NO-) complexes, compatible (on the basis of the simple molecular orbital theory) with a bent NO geometry. The formation of a complex family of Fe2+ mono-, di-, and trinitrosyl complexes was also confirmed by FTIR spectroscopy. Similarly to what was observed in the oxidation experiments, the fraction of extraframework Fe sites able to interact with NO in Fe-MCM-22 sample is smaller than that in Fe-silicalite treated in the same conditions. This trend is explained with a major clustering of extraframework Fe sites in Fe-MCM-22 sample, as was also suggested by FTIR experiments. These results suggest that the dispersion of iron in zeolitic matrixes prepared by isomorphous substitution could also depend on the zeolitic structure.
|
2022-12-17T23:45:48.576Z
|
18,372,696 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1002/EJSP.757",
"MAG": "2183776508",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In many non-human primate species, a display of red by a female increases attraction behavior in male conspecifics. In two experiments, we investigate an analogous effect in humans, specifically, whether red on a woman's shirt increases attraction behavior in men. In Experiment 1, men who viewed an ostensible conversation partner in a red versus a green shirt chose to ask her more intimate questions. In Experiment 2, men who viewed an ostensible interaction partner in a red versus a blue shirt chose to sit closer to her. These effects were observed across participants' perceptions of their own attractiveness (Experiment 1) and general activation and mood (Experiment 2). Our findings suggest that red acts as a basic, non-lexical prime, influencing reproduction-relevant behavior in like manner across species. Copyright © 2010 John Wiley & Sons, Ltd.
|
2022-12-19T17:52:36.096Z
|
242,217,687 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.31219/osf.io/dh6qv",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://osf.io/dh6qv/download"
}
|
Oral Cancer is one of the leading causes of death in India, specifically in its Northeastern region. India holds about one third cases of the total oral cancer in the world. According to a report (2018), India holds 1,19,992 new cases of oral cancer and 72,616 deaths. Current approaches in cancer treatment mainly include surgery, chemotherapy and radiation therapy. These treatments often give a morbid outcome and reduce survival rate. This is mainly due to their non-selective nature to kill the tumor cells along with the normal cells. Recently the potential of Cold Atmospheric Plasma (CAP) in cancer treatment is gaining great interest among scientists and researchers. This is mainly due to the enhanced selective nature of the CAP in targeting and killing the tumor cells without affecting the surrounding tissue and causing minimal side effects. Reactive Oxygen and Nitrogen species (RONS) are the main contributors of the efficacy of CAP in killing cancer cells. Although many attempts have been made to understand the underlying mechanism of CAP in cancer treatment, there is a lack of detailed studies with respect to different treatment conditions. The use of CAP can be a potential innovative therapy in the upcoming days and more clinical trials should be encouraged to prove its efficacy and relevance in clinical purpose.
|
2022-01-27T18:48:27.315Z
|
135,598,703 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4028/www.scientific.net/MSF.587-588.650",
"MAG": "2029096068",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Polycrystalline ingots of Co70-xNixGa30 (22 ≤ x ≤ 25) alloys were prepared by a sequence of arc melting high purity Co, Ni and Ga in argon atmosphere, followed by homogenization at 1150°C under a pressure of 10-3 Pa, and quenching in ice water. Structural characterisation of the quenched alloys was carried out to verify the presence of the martensite phase at room temperature. The martensite start (Ms), martensite finish (Mf), austenite start (As) and austenite finish (Af) temperatures for the alloys were determined using a differential scanning calorimeter. The ferromagnetic to paramagnetic phase transition temperature (TC) of the alloys was determined using an indigenously developed ac susceptometer. All the alloys are FSMAs with Ms, Af and TC above room temperature. The composition dependence of the properties of these alloys could be understood on the basis of the e/a (electrons to atom) ratio and the Co/Ni ratio. Presence of γ-phase precipitates along with the β-phase in these alloys enhances the ductility as well as influences the physical properties of these alloys.
|
2022-02-09T11:34:50.569Z
|
244,632,249 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4322/conpat2021.635-",
"MAG": "3205274624",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Os revestimentos desempenham relevante papel na durabilidade das alvenarias dos edifícios, já que asseguram proteção contra as ações agressivas de natureza física, mecânica, química, biológica e/ou antrópica. Este trabalho objetiva identificar as principais anomalias, formas de manifestação e suas possíveis causas, em fachadas de edifícios do século XIX em Salvador. De caráter qualitativo e exploratório, esta pesquisa seguiu método científico de abordagem empírica, a partir da realização de levantamento bibliográfico sobre o tema, seguido de análise crítico-comparativa. A originalidade deste estudo se encerra na contemporaneidade da sua execução. Como resultado, obteve-se a sistematização dos danos e suas causas mais prováveis, o que contribui para a elaboração de diagnóstico detalhado e tomada de decisões em intervenções para preservação do patrimônio edificado. ABSTRACT Coatings play an important role in the durability of building masonry, as they ensure protection against aggressive physical, mechanical, chemical, biological and anthropic actions. This work aims to identify the main anomalies, forms of manifestation and their possible causes on the façades of 19th century buildings in Salvador. With a qualitative and exploratory character, this research followed a scientific method with an empirical approach, based on a bibliographical survey on the subject, followed by a critical-comparative analysis. The originality of this study ends in the contemporaneity of its execution. As a result, systematization of anomalies and their most probable causes was obtained, which contributes to the elaboration of a detailed diagnosis and decision-making in interventions for the preservation of the built heritage.
|
2022-06-14T04:26:11.646Z
|
144,563,878 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1179/hso.2011.4.1.59",
"MAG": "2039691370",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract Cultural heritage policies are no longer the sole monopoly of sovereign states. Therefore, this article investigates the need for a European civil society in the field of cultural heritage according to the analysis of policy documents and published literature. The article finds that European policies in the field of cultural heritage before 1990 were oriented towards the formation of a common European identity. In the 1990s a paradigm shift emerged: cultural heritage now reflects the cultural diversity of the common European heritage or "unity in diversity." Simultaneously, the value of heritage for society and the need to engage civil society in maintaining, promoting, and safeguarding cultural heritage has received more emphasis. This new approach is reflected in the concept of "heritage community," as articulated in the 2005 Faro Convention of the Council of Europe. Moreover, the European Community promulgated its desire to involve civil society more closely into its activities in the field of culture with its 2007 "A European Agenda for Culture" (European Union 2007). Although a European civil society in the field of cultural heritage is still in its infancy, the road to its establishment has been paved.
|
2022-09-07T04:00:43.900Z
|
57,099,114 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1117/12.708403",
"MAG": "2014093206",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Purpose: The first clinical facility for synchrotron radiation (SR) mammography is now operative at the SYRMEP beamline of ELETTRA, the SR facility in Trieste, Italy. The mammographic facility and the preliminary results of the clinical trial are presented in this contribution. Method and Materials: The distance between the SR source and the patient is about 30 m; the main features of the X-ray beam are: monochromaticity at ~0.2% bandwith in the energy range 8-35 keV, photon flux of about 108 ph/(mm2 s) and dimensions of 21 cm x 3.5 mm at the compressed breast. An innovative dosimetric system allows the on-line dose control during the examination. The images are acquired by scanning the patient, in prone position, in front of the stationary laminar beam; the average scanning time is about 10 s. The detector is a screen film system; it is at ~2 m from the breast in order to fulfil the so-called Phase Contrast (PhC) requirements. The breast thickness and glandularity defines the optimal beam energy for each examination. The patients are enrolled by radiologists, after routine examinations, on the basis of BI-RADS classification, according the research program approved by the local Ethical Committee. Results: This communication concerns the first 9 patients underwent the SR PhC mammography; the images match the quality obtained in previous in vitro studies. With reference to conventional mammography the diagnostic quality of the radiological images is better, without increasing the delivered dose to the patient.
|
2022-09-13T17:57:55.452Z
|
31,144,096 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/00006842-198306000-00006",
"MAG": "2328162270",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
&NA; Three modified replications (N = 32, 46, and 32) investigated verbal and nonverbal interactions during role playing of family conflict by family groups of father, mother, and one child. Half the fathers had essential hypertension and half were normotensive. Nonverbal but not verbal behavior differed between families with hypertensive vs. normotensive fathers. Hypertensive fathers and their normotensive wives and children looked at each other less (gaze aversion), both while listening and speaking, than did the members of normotensive families. The difference in duration of gaze aversion occurred more prominently during emotionally negative verbalizations. The results suggest a pattern of conflict avoidance in families with a hypertensive father.
|
2022-09-13T20:08:17.810Z
|
8,633,841 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/00207721003768159",
"MAG": "2146946469",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
New fusion predictors for continuous-time linear systems with different types of observations are proposed. The fusion predictors are formed by summation of the local Kalman filters/predictors with matrix weights depending only on time instants. The relationship between fusion predictors is established. High accuracy and computational efficiency of the fusion predictors are demonstrated on the several examples such as the damper harmonic oscillator motion with multisensor environment.
|
2022-09-14T20:30:26.174Z
|
253,015,342 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.23917/indigenous.v7i2.17241",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://journals.ums.ac.id/index.php/indigenous/article/download/17241/7827"
}
|
. Insomnia is the most common sleep disorder reported by the public, which impacts disrupting activities during the day and worsening body health. Therefore, interventions are needed to improve the quantity and quality of sleep for the body to be healthier. This study aims to analyze the content validity and the effect of applying dhikr breathing relaxation therapy on insomniacs. This research and development involved five experts/psychologists with a minimum education of a master’s in psychology and nine people with insomnia in their productive age domiciled in Surakarta as the research subjects. Insomnia subjects were chosen using the sequential-random sampling method and selected utilizing the Insomnia Severity Index (ISI). The measuring instrument used was a content validity assessment questionnaire assessed by experts (raters). The content validity analysis employed Aiken's V coefficient, and the effect of the therapy application was analyzed descriptively from qualitative data in the form of interviews a week after the therapy application on the subjects with insomnia. The validation test results obtained an average V value of 0.981. The analysis results showed that the effects of applying the therapy model, in general, had a positive influence on improving sleep quality, characterized by ease of entering sleep, reducing the frequency of awakening during sleep, and waking up refreshed. In conclusion, the dhikr breathing relaxation therapy model has a positive effect on improving sleep quality. This study implies that the dhikr breathing relaxation therapy model is appropriate and feasible to use as a therapy to reduce insomnia symptoms.
|
2022-10-21T17:38:44.167Z
|
28,306,081 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1046/j.1365-2222.2002.01281.x",
"MAG": "2091537153",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Background Increased production of IL‐4 and IL‐5 and decreased production of IFN‐γ by CD4+ T cells has been implicated in asthma pathogenesis. However, CD8+ T cells also produce type 1 and type 2 cytokines and the relative roles of CD4+ and CD8+ T cell cytokine production in asthma have not been previously studied.
|
2022-12-17T11:05:55.291Z
|
97,141,102 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1346/CCMN.2001.0490505",
"MAG": "2140430991",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Inductively coupled plasma-mass spectrometry (ICP-MS) is ideally suited for the rapid and simultaneous analysis of multiple elements in geological materials, including soils, organic substances and most rock types (Eggins et al., 1997; Longerich et al., 1990; Jenner et al., 1990). The application to clay minerals is more recent (Jain et al., 1994). This technique is highly sensitive, and is capable of analyzing a wide range of isotopes covering the entire mass spectrum. Consequently, ICP-MS is used to measure directly rare earth and platinum group elements at ppb levels without preconcentration.
Commercial ICP-MS instrumentation was introduced in 1983. Since that time it has become an acceptable tool for geochemical analysis. Like most analytical techniques, however, accurate and precise quantitative measurements require special considerations. For example, mass-dependent matrix effects, mass spectral interferences, and drift must be monitored closely and corrections applied to the data to obtain quantitative analyses. Also, this is a solution-based technique, and therefore solid samples must be digested. Quantitative results require the use of external calibration …
|
2022-12-17T22:58:24.593Z
|
150,061,394 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/10400419.2018.1530533",
"MAG": "2900681295",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Creative people regulate their own attentional flexibility and focus in response to creative task demands in a way that favors the emergence of original and effective solutions. So far, not much is known about the neurobiological mechanisms that underlie such abilities. Here, the function of the locus coeruleus noradrenaline (LC-NA) system in creativity was explored using pupillometry. Two studies experimentally tested whether tonic pupil dilation (as a proxy for measuring tonic LC-NA activity) and phasic pupil dilation (as a proxy for measuring phasic LC-NA activity) predicted performance on divergent and convergent thinking using both psychometric (study 1) and real-world creativity tasks (study 2). During divergent thinking, it was consistently found that tonic pupil dilation predicted the generation of original ideas in both creativity tasks, and phasic pupil dilation predicted the generation of effective ideas only in the real-world creativity task. However, during convergent thinking, tonic and phasic pupil dilation did not predict creative task performance in both creativity tasks. Therefore, this study was the first to provide experimental evidence that suggests that tonic and phasic LC-NA activity differentially predict the generation of original and effective ideas during creative tasks that require divergent thinking.
|
2022-12-12T00:27:33.122Z
|
214,623,169 |
{
"externalids": {
"ACL": null,
"ArXiv": "2003.10580",
"DOI": "10.1109/CVPR46437.2021.01139",
"MAG": "3014034447",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We present Meta Pseudo Labels, a semi-supervised learning method that achieves a new state-of-the-art top-1 accuracy of 90.2% on ImageNet, which is 1.6% better than the existing state-of-the-art [16]. Like Pseudo Labels, Meta Pseudo Labels has a teacher network to generate pseudo labels on unlabeled data to teach a student network. However, unlike Pseudo Labels where the teacher is fixed, the teacher in Meta Pseudo Labels is constantly adapted by the feedback of the student’s performance on the labeled dataset. As a result, the teacher generates better pseudo labels to teach the student.1
|
2022-12-29T14:44:31.421Z
|
22,734,426 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CICED.2016.7576180",
"MAG": "2527617026",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Based on the load data of Tianjin, the paper analyzes power grid load characteristic curves, and discusses influence factors. Firstly, the paper focus on the current situation of load development and the characteristics of power consumption structure are based on the situation of supply and demand, power consumption structure, and industrial structure. Secondly, the paper analyzes the annual load characteristics of Tianjin power grid, including load characteristics, typical daily load characteristics. Finally, the paper discusses the main factors influencing the load characteristics of Tianjin power grid.
|
2022-02-12T19:56:20.454Z
|
9,070,201 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2307/3279329",
"MAG": "2313614319",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The survival of infective larvae of Ancylostoma caninum on outdoor grass plots was studied in 40 experiments over 1 year. Weather data were collected over the period. Mean larval survival from August to early November was 24 days (range 1 to 49), from December through February was 0 days, and from March to mid-August was 6.6 days (range 0 to 21). Moderate to high temperatures and substantial rainfall favored larval survival; low temperatures and rainfall favored larval destruction.
|
2022-09-08T18:51:43.047Z
|
232,384,820 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/children8030227",
"MAG": "3136199572",
"PubMedCentral": "8002329"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2227-9067/8/3/227/pdf?version=1615968674"
}
|
Advances in neuroimaging of the preterm infant have enhanced the ability to detect brain injury. This added information has been a blessing and a curse. Neuroimaging, particularly with magnetic resonance imaging, has provided greater insight into the patterns of injury and specific vulnerabilities. It has also provided a better understanding of the microscopic and functional impacts of subtle and significant injuries. While the ability to detect injury is important and irresistible, the evidence for how these injuries link to specific long-term outcomes is less clear. In addition, the impact on parents can be profound. This narrative summary will review the history and current state of brain imaging, focusing on magnetic resonance imaging in the preterm population and the current state of the evidence for how these patterns relate to long-term outcomes.
|
2022-11-04T00:42:15.669Z
|
165,784,682 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.18781/R.MEX.FIT.1803-3",
"MAG": "2888458959",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A partir de muestras de trigo de la variedad CIRNO C2008 con síntomas de tizón foliar y provenientes del Sur de Sonora, México, se obtuvieron cuatro aislados de Bipolaris sorokiniana y cuatro de Alternaria alternata. Las especies fúngicas se identificaron mediante caracterización morfológica y análisis de secuencias ITS del DNA ribosomal. En invernadero, se inocularon los ocho aislados en 13 variedades de trigo harinero (Triticum aestivum) y 6 de trigo cristalino (Triticum durum). La agresividad de los aislados se evaluó con una escala de severidad de 1 a 9, donde 1 fue lesiones mínimas y 9 necrosis y clorosis generalizada que indicó susceptibilidad. Las variedades Vicam S70, Kronstad F2004 y Río Bravo C2016 fueron moderadamente resistentes a B. sorokiniana; en contraste, Bárcenas S2002, Morocco, Borlaug 100 F2014, Bacanora T88, Luminaria F2012, la línea avanzada C, Villa Juárez F2009, Maya S2007, Urbina S2007, PBW343, Nana F2007, Local red, Noio y la línea avanzada JC fueron altamente susceptibles. Adicionalmente, se observó que A. alternata es un patógeno secundario que invade las lesiones provocadas por B. sorokiniana.
|
2022-12-16T15:48:30.445Z
|
24,461,045 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1200/JCO.2002.11.114",
"MAG": "1979320325",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
PURPOSE
We investigated the feasibility, safety, and antitumor activity of weekly gemcitabine given in combination with low doses of cisplatin and ifosfamide in previously treated patients with advanced transitional-cell carcinoma (TCC) of the urothelium.
PATIENTS AND METHODS
Patients with measurable, metastatic or unresectable TCC who had received one or two prior chemotherapy regimens were eligible. On a 28-day course, doses of cisplatin 30 mg/m(2), gemcitabine 800 mg/m(2), and ifosfamide 1 g/m(2) were given on day 1 and then repeated on day 8 and day 15 unless there was dose-limiting hematologic toxicity.
RESULTS
Fifty-one patients were registered; 10 patients participated in a pilot study, after which 41 patients were registered onto the phase II protocol. Forty-eight patients (94.1%) had dose-limiting hematologic toxicity on day 8 or day 15. Nonhematologic toxicity of grade 3 or greater consisted mainly of nausea and vomiting (seven patients, 13.7%) and infection (seven patients, 13.7%). Responses could be assessed in 49 of 51 eligible patients; two complete responses (4.1%) and 18 partial responses (36.7%) were observed for an overall response rate of 40.8% (exact 95% confidence interval, 27% to 56%).
CONCLUSION
This regimen of cisplatin, gemcitabine, and ifosfamide is not feasible for weekly administration because of hematologic toxicity. Nevertheless, there was promising activity with only two doses per 28-day cycle. On the basis of these results, we have initiated a phase II trial of this combination given as a single dose every 14 days in patients with untreated, metastatic urothelial carcinoma.
|
2022-12-17T21:08:32.920Z
|
218,680,317 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/21505594.2020.1770482",
"MAG": "3025149794",
"PubMedCentral": "7549962"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.tandfonline.com/doi/pdf/10.1080/21505594.2020.1770482?needAccess=true"
}
|
ABSTRACT Nuclear localization of cytoplasmic RNA virus proteins mediated by intrinsic nuclear localization signal (NLS) plays essential roles in successful virus replication. We previously reported that NLS mutation in the matrix (M) protein obviously attenuates the replication and pathogenicity of Newcastle disease virus (NDV), but the attenuated replication mechanism remains unclear. In this study, we showed that M/NLS mutation not only disrupted M’s nucleocytoplasmic trafficking characteristic but also impaired viral RNA synthesis and transcription. Using TMT-based quantitative proteomics analysis of BSR-T7/5 cells infected with the parental NDV rSS1GFP and the mutant NDV rSS1GFP-M/NLSm harboring M/NLS mutation, we found that rSS1GFP infection stimulated much greater quantities and more expression changes of differentially expressed proteins involved in host cell transcription, ribosomal structure, posttranslational modification, and intracellular trafficking than rSS1GFP-M/NLSm infection. Further in-depth analysis revealed that the dominant nuclear accumulation of M protein inhibited host cell transcription, RNA processing and modification, protein synthesis, posttranscriptional modification and transport; and this kind of inhibition could be weakened when most of M protein was confined outside the nucleus. More importantly, we found that the function of M protein in the cytoplasm effected the inhibition of TIFA expression in a dose-dependent manner, and promoted NDV replication by down-regulating TIFA/TRAF6/NF-κB-mediated production of cytokines. It was the first report about the involvement of M protein in NDV immune evasion. Taken together, our findings demonstrate that NDV replication is closely related to the nucleocytoplasmic trafficking of M protein, which accelerates our understanding of the molecular functions of NDV M protein.
|
2022-12-17T23:31:46.287Z
|
199,086,717 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1049/ET.2019.0434",
"MAG": "2958948448",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This edition tells the story of 'Germania', and the engineers behind the infamous reminder of Hitler's Impossible City - a grand place to house the 'Master Race'.
|
2022-02-08T05:54:39.293Z
|
6,682,196 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1504/IJMC.2013.055751",
"MAG": "2064573201",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This study applied a stated preference survey method to investigate the impact of graphical route information panels GRIPs on taxi drivers' diversion decisions. A cross-sectional ordered logit model and a panel data ordered logit model were developed. Main findings are: taxi drivers and mid-age drivers with high urban freeway use frequency are more likely to divert; drivers are more likely to divert if the original ramp is jammed and an accident occurs; employer-provided car drivers are less sensitive to accident and less likely to divert. On the modelling aspect, the panel data model does not provide substantially different model coefficients but more robust statistical inferences; the cross-sectional model tends to seriously overestimate t-test values for explanatory variables changing across drivers and tends to slightly underestimate t-test values for explanatory variables changing across trip scenarios and interaction terms. The findings have implications for GRIP assessment and for future response behaviour modelling effort.
|
2022-02-13T09:45:53.494Z
|
121,537,628 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1103/PhysRev.132.927",
"MAG": "2024395932",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Anomalous thresholds of the square diagram and their effect on the two- particle unitarity integral are discussed. It is shown for a certain diagram that the three-particle unitarity integral does not have counter terms that cancel the singularity from the two-particle contribution. Consistency with the crossed-channel unitarity is also discussed. (auth)
|
2022-03-01T19:47:33.984Z
|
219,775,464 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1200/jco.2020.38.15_suppl.e23501",
"MAG": "3029295203",
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},
"license": null,
"status": null,
"url": null
}
|
e23501Background: Ewing sarcoma family of tumors (ESFT) is a rare malignancy among adults. Most studies from western countries have reported improvement in outcomes following multi-agent chemothera...
|
2022-01-27T03:52:49.844Z
|
225,767,865 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21608/jarch.2020.99390",
"MAG": "3041437834",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The entire systems of the Near East were deeply affected by series of the crises and changes which reshaped the political organization and formed the watershed moment between the Bronze and Iron Age. Shortly after 1200 B.C., most of these political systems had abruptly collapsed due to the arrival of foreign invaders from the west. The clash of invaders had drastic effects in the light of the decline which afflicted with the major powers and a number of the Bronze Age centers also came to an end. Obviously, wars, deportations, and production, definitely in Anatolia, became an endemic problem by the end of the Late Bronze Age.
|
2022-07-09T11:26:02.893Z
|
13,524,486 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S1041610203009050",
"MAG": "2123250848",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Although vascular dementia was described over a century ago, it remains a difficult and challenging diagnosis. Several sets of clinical criteria have been published in an effort to establish the presence or absence of vascular dementia in a standardized fashion. Clinical studies have demonstrated that they identify different groups of patients and are thus not interchangeable. Retrospective clinicopathological correlations have shown that most are insufficiently sensitive, although they are generally relatively specific. They accurately exclude pure Alzheimer's disease but may include 9% to 39% of mixed dementia cases (Alzheimer's disease and vascular dementia combined). Further studies are needed to develop better performing criteria that could lead to a broad consensus on the clinical diagnosis of vascular and mixed dementia.
|
2022-09-07T07:47:44.350Z
|
123,135,051 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1103/PHYSREVB.80.035126",
"MAG": "2093478598",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Using density-functional calculations and the modern theory of polarization, we study the structure and polarization responses of tetragonal ${\text{PbTiO}}_{3}$, ${\text{BaTiO}}_{3}$, and ${\text{SrTiO}}_{3}$ in a strain regime that is previously overlooked. We find that the ${\ensuremath{\chi}}_{3}$ polarizations in all three substances saturate at large strains, revealing a phenomenon that is generally applicable. The saturation demonstrates the existence of a sophisticated collective behavior in the large-strain regime and is shown to originate possibly from electron-ion correlation that leads to a cancellation between electronic and ionic polarizations. Our results shed insight on the polarization properties and provide explanations for the puzzling results recently observed in experiments.
|
2022-09-09T12:40:40.482Z
|
96,961,011 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5897/AJB2005.000-3053",
"MAG": "2152616554",
"PubMedCentral": null
},
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Levels of lead, iron, zinc, copper, arsenic, cobalt, chromium, manganese, mercury and cadmium, as well as the microbial profile were determined in water samples from Aba River. Physico-chemical examinations revealed that manganese (0.03 mg/l), zinc (4.81 mg/l) and copper (0.19 mg/l) were below the maximum allowable levels set by the United States Environment Protection Agency (USEPA), while lead (0.064 mg/l), iron (0.81 mg/l), arsenic (0.1 mg/l) chromium (0.006 mg/l) and mercury (0.009 mg/l) were high but not significantly. The implication is that waste assimilation capacity of the river is high, a phenomenon attributable to dilution, sedimentation and depuration. Quantitative examinations of the microorganisms present revealed that as many as 2.05 x 108 viable bacterial (cfu/ml) were present. The predominant bacterial forms include Staphylococcus species, Streptococcus faecalis, Escherichia coli, Salmonella species, Bacillus and Clostridium species implying that the abattoir wastes discharged into the river may have had a significant impact on the river ecosystem. African Journal of Biotechnology Vol. 4 (3), pp. 266-272, 2005
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2022-12-03T11:40:42.442Z
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