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135,612,827 |
{
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"DOI": "10.3233/BSI-140097",
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|
Biomedical optical imaging and optical spectroscopy are rapidly emerging as strong contenders for non-invasive optical biopsy. In biomedical imaging, Optical Coherence Tomography (OCT) is an established imaging modality for non- contact depth-resolved three-dimensional imaging with micrometer scale resolution. OCT provides label-free micro-structural morphological information of the tissue. Raman spectroscopy is a complementary tool for obtaining molecular-specific infor- mation for diagnosis. This article provides a brief overview of the underlying principles of OCT and Raman spectroscopy, their instrumentation with representative latest developments in cancer diagnosis.
|
2022-08-24T22:42:51.307Z
|
205,799,158 |
{
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"DOI": "10.1080/13693780701874515",
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"url": "https://academic.oup.com/mmy/article-pdf/46/4/371/2899020/46-4-371.pdf"
}
|
While most patients with cryptococcosis have obvious cellular immune deficiency, a minority have no apparent predisposing factors. However, in the latter there may be subtle innate immune system deficiencies which go unrecognized. Mannose-binding lectin (MBL) deficiency is associated with increased susceptibility to infectious diseases and may predispose to cryptococcosis, particularly when it disseminates to the central nervous system (CNS) in apparently immunocompetent patients. MBL function and levels, as well as MBL2 genotype were determined in 36 HIV-negative cryptococcosis patients (25 with CNS involvement) using C4 deposition and mannan-binding ELISA. MBL deficiency was defined using C4 deposition level < 0.2 U/microl or mannan-binding level < 0.5 microg/ml. MBL results were compared between patients with cryptococcosis and healthy controls and among the cryptococcosis patients according to the site of their disease. There was no difference in MBL function, mannan-binding level or increase in the frequency of MBL deficiency or low producing MBL2 genotypes in any of these comparisons. Patients with CNS cryptococcosis were no more likely to be MBL deficient than those with non-CNS disease. It appears that MBL deficiency is not associated with cryptococcosis in non-immunocompromised hosts. Beta errors consequent on the small number of patients studied may account for the lack of association.
|
2022-12-13T18:31:42.131Z
|
247,732,604 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.3390/ijerph19073920",
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"PubMedCentral": "8998001"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/1660-4601/19/7/3920/pdf?version=1648200401"
}
|
The increasing prevalence and impact of trauma, such as adverse childhood experiences, race-based trauma, and a global pandemic, highlight the critical need for a flexible multisystemic framework of resilience. This manuscript outlines the universality of trauma and resilience and also provides a description of the gaps in existing resilience frameworks that led to the development of a flexible multisystemic resilience framework entitled the ARCCH Model of Resilience. Attachment, Regulation, Competence, Culture, and Health are elements of personal and cultural identities, families, communities, and systems that can be used to evaluate strengths, identify areas that need support, and provide steps for culturally responsive and ecologically valid interventions. A multisystemic application of ARCCH is provided.
|
2022-08-29T22:24:35.672Z
|
206,823,906 |
{
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"ArXiv": null,
"DOI": "10.1177/2049463713502944",
"MAG": "2095829161",
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},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc4590176?pdf=render"
}
|
Chronic pain is a long-term condition, which has a major impact on patients, carers and the health service. Despite the Chief Medical Officer setting chronic pain and its management as a national priority in 2008, the utilisation of health services by patients with long-term conditions is increasing, people with pain-related problems are not seen early enough and pain-related attendances to accident and emergency departments is increasing. Early assessment with appropriate evidence-based intervention and early recognition of when to refer to specialist and specialised services is key to addressing the growing numbers suffering with chronic pain. Pain education is recommended in many guidelines, as part of the process to address pain in these issues. Cardiff University validated an e-learning, master’s level pain management module for healthcare professionals working in primary and community care. The learning outcomes revolve around robust early assessment and management of chronic pain in primary and community care and the knowledge when to refer on. The module focuses on the biopsychosocial aspects of pain and its management, using a blog as an online case study assessment for learners to demonstrate their knowledge, understanding and application to practice. The module has resulted in learners developing evidence-based recommendations, for pain management in clinical practice.
|
2022-12-15T02:24:54.800Z
|
250,691,500 |
{
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"ArXiv": null,
"DOI": "10.1088/1742-6596/150/2/022002",
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"license": null,
"status": "GOLD",
"url": "https://doi.org/10.1088/1742-6596/150/2/022002"
}
|
Low temperature transport of a well-defined open-quantum dot has been studied via scanning gate microscopy (SGM). The open dot was fabricated on AlGaAs/GaAs heterostructure using trenches defined via electron beam lithography and a wet etching. The active size of the quantum cavity is approximately 1 μm × 1 μm. The SGM observation was performed at low temperature with a conductive piezolever, which is lifted up 50 nm above the surface with applied a negative voltage. During the scan of the tip, resistance across the dot is measured in a four-probe configuration and stored in a SPM controller synchronized with the position of the tip. The SGM response at zero-magnetic field shows a high resistance when the tip situates onto a line along the inlet and the outlet of the dot. The image could be understood as that the tip induced potential disturbs the current flow in the dot and it results in the increase of resistance. Such an image can be obtained even at more than 8 K, therefore this image would correspond to a classical transport. On the other hand, the image obtained at less than 2 K shows almost similar image as that observed at higher temperature. However, after subtracting the high temperature image as the back ground structure, which is achieved by a high pass filtering, conductance fluctuations are visualized in the low temperature image. These fluctuations would be attributed to a change of quantum interference condition as well as a manipulation of the wave-function confined in the open quantum dot.
|
2022-12-11T07:04:12.701Z
|
145,450,503 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1080/1547688X.2014.925747",
"MAG": "2114052107",
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"url": null
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|
In this era of globalization, students need to know how to write well. Faculty development needs to focus on assisting primary teachers as they prepare students for a twenty-first-century world. Strategic curriculum reform and professional development can be achieved by partnerships between district administrators and professional consultants. Two university professors introduced writing workshop in the classrooms of skills-oriented first grade educators. The teachers’ new methodology encouraged students to produce writing that originated from their classroom and life experiences. After the professional development, the teachers devised a month-by-month skill and genre chart to guide their instruction in the following year.
|
2022-02-09T06:31:04.549Z
|
129,354,381 |
{
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"ArXiv": null,
"DOI": "10.1063/PT.3.2297",
"MAG": "2027510309",
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},
"license": null,
"status": null,
"url": null
}
|
A theory of how shifting winds shape sandy terrain has passed a long-awaited experimental test.
|
2022-02-09T14:46:43.151Z
|
81,144,785 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4172/1758-4272.1000203",
"MAG": "2898239253",
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://www.openaccessjournals.com/articles/technology-rationale-for-the-development-of-cellular-matrix-acpha-kit-certified-medical-device-allowing-the-combination-.pdf"
}
|
The composition of synovial fluid of patients suffering from osteoarthritis (OA) is altered with reduced concentration and molecular weight of Hyaluronic Acid (HA) and augmentation of catabolic enzymes and inflammatory markers. Intra-Articular (IA) injections of exogenous HA aim to restore the rheological properties of the synovial fluid in the osteoarthritic joints. However, clinical studies have shown that the benefit of HA injections lasts only for around 6 months and that many patients don’t respond well to repeated course of HA treatment. On the other side, platelet rich plasma (PRP) IA injections have been shown to reduce pain and improve joint mobility, probably by modulating the expression of catabolic enzymes and inflammatory markers. As injections of HA and PRP use different pathway to alleviate symptoms in OA patients, the concept of combining these two treatments has emerged recently. In vitro evaluations and preliminary studies have demonstrated the therapeutic potential of this new therapeutic approach for OA treatment. To meet the needs of medical practitioners that want to treat their patients with this new treatment option, an innovative medical device, the CellularMatrix A-CP-HA Kit, has been specifically designed. This device is the first certified medical device that allows the combination of PRP and HA in manner compliant with medical devices regulation and good clinical practice.
|
2022-02-11T02:48:07.072Z
|
111,312,953 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1115/OMAE2003-37186",
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"status": null,
"url": null
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|
It has been shown that probabilistic model is an effective tool in assessing structural reliability incorporating the information from non-destructive inspection (NDT) of offshore structures. However, the preceding theorems fail to adequately deal with the uncertainties of fuzzy character that are associated with NDT for offshore structures. This paper is aimed at an initial investigation on reliability theory of structure involved with fuzziness considering inspection and maintenance. Based on the basic principles of fuzzy set theory, a fuzzy Bayesian procedure is proposed to quantify the fuzzy uncertainty, including the NDT uncertainty in the flaw size determination and the flaw detection, the modeling uncertainty in model selection and the uncertainty in distribution parameter. This paper presents an algorithm to compute the posterior probability of model weights and the posterior distribution of distribution parameter employing the fuzzy Bayesian theorem. The prior probabilities of model weights may be determined based on fuzzy synthetic evaluation. A method for reliability assessment upon inspection and maintenance considering fuzzy uncertainties is put forward in this paper. The example is investigated to illustrate the validation of the proposed method. It is found that the effect of fuzzy uncertainties could be very significant in assessing structural reliability.Copyright © 2003 by ASME
|
2022-02-10T04:20:39.548Z
|
6,045,917 |
{
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"ArXiv": null,
"DOI": "10.1111/j.1745-7254.2005.00202.x",
"MAG": "1912779421",
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"license": null,
"status": "BRONZE",
"url": "https://www.nature.com/articles/aps2005172.pdf"
}
|
AbstractAim:To develop a homogeneous high-throughput screening (HTS) assay based on scintillation proximity assay (SPA) technology for identification of novel α4β2 nicotinic acetylcholine receptor (nAChR) modulators.Methods:Membrane preparation of HEK293 cells expressing α4β2 nAChR, [3H]cytisine and wheat germ agglutinin (WGA)-coupled microbeads were used to develop an HTS assay based on SPA technology. This method was validated against a conventional filter binding approach and applied to large-scale screening of a library containing 32 000 synthetic compounds. Intracellular calcium measurement was carried out to verify the bioactivities of the hits found by the SPA assay.Results:IC50 values of 2 reference compounds (epibatidine and RJR 2403) determined by SPA and filter binding methods were comparable and consistent with those reported elsewhere. A total of 54 compounds, showing more than 60% competitive inhibition on [3H]cytisine binding to α4β2 nAChR, were identified initially following an HTS campaign. Secondary screening confirmed that 17 compounds with novel chemical structures possessed relatively high binding affinity to α4β2 nAChR (Ki<2 μmol/L). Eight compounds displayed antagonistic effects with >50% inhibition on ABT-594-induced calcium mobilization while none showed any agonist activity.Conclusion:This homogeneous binding assay is a highly efficient, amenable to automation and robust tool to screen potential α4β2 nAChR modulators in an HTS setting. Its application may be expanded to other membrane receptors and ion channels.
|
2022-09-01T20:11:53.345Z
|
85,594,929 |
{
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"ArXiv": null,
"DOI": "10.3109/10242422.2015.1076215",
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"status": null,
"url": null
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|
Abstract Production of protease-resistant phytase by Aspergillus oryzae SBS50 was optimized in solid state fermentation using wheat bran as substrate. An integrated statistical optimization approach involving the Placket–Burman design followed by response surface methodology was employed. Among all the variables tested, incubation period, triton X-100, moisture ratio, and magnesium sulphate were identified as significant and further optimized using response surface methodology that resulted in 3.35-fold improvement in phytase production from 55.43 to 185.75 U/g dry mouldy bran (DMB). Optimal conditions for maximum phytase production (185.75 U/g DMB) included wheat bran 10 g per 250 ml flask moistened with 35 ml distilled water supplemented with 3.0% triton X-100, 0.04% magnesium sulphate, 1.0% sucrose and 0.5% yeast extract incubated at 30 °C for an incubation time of 48 h. Phytase titers were sustainable (179.55 to 185.75 U/g DMB), when the mould was grown in shake flasks of varied volumes and enamel-coated metallic trays under optimized conditions. Fermentation time was reduced to half from 96 h to 48 h after optimization resulting in a 6.7-fold enhancement in the phytase productivity from 577.39 to 3868.75 U/Kg/h and thus, reducing the cost of enzyme production. Phytase released inorganic phosphate, reducing sugars and soluble proteins from different food samples in a time dependent manner as a result of phytate hydrolysis.
|
2022-09-12T08:55:59.370Z
|
56,363,565 |
{
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"ArXiv": null,
"DOI": "10.15232/S1080-7446(15)30108-X",
"MAG": "2280261419",
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"license": null,
"status": null,
"url": null
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|
Three experiments were conducted to evaluate effects of including copra meal, palm kernel expellers (PKE), and palm kernel meal (PKM) in diets for weanling pigs from approximately 9 to 20 kg of BW. A total of 128, 128, and 160 pigs were used in the experiments with copra meal, PKE, and PKM, respectively. In each experiment, pigs were randomly allotted to 4 dietary treatments with 4 or 5 pigs per pen and 8 replicates per treatment. The control diet was based on corn, soybean meal, and 4% fish meal. Three additional diets were formulated by including 5, 10, or 15% copra meal, PKE, or PKM at the expense of corn and soybean meal. Diets were formulated to contain equal quantities of digestible AA and P, and ME. Pigs were fed experimental diets for 20 or 21 d, and ADG, ADFI, and G:F were calculated. Results indicated that pigs fed increasing levels of copra meal had a linear reduction (P < 0.05) in final BW, overall ADG, and ADFI, but overall G:F was unaffected. Pigs fed increasing levels of PKE had a linear reduction (P < 0.05) in final BW and overall ADG, but overall ADFI and G:F were not influenced. No differences were observed in growth performance if PKM was used. In conclusion, if diets are formulated based on digestible nutrients and ME, diets for weanling pigs may include up to 15% PKM without affecting overall growth performance, but if copra meal or PKE is used, pig performance may be reduced.
|
2022-08-30T16:13:10.934Z
|
237,939,705 |
{
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"ArXiv": null,
"DOI": "10.3390/antiox10091461",
"MAG": null,
"PubMedCentral": "8464857"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2076-3921/10/9/1461/pdf?version=1631623030"
}
|
In the last two decades, the interest in natural plant feed additives (PFA) as alternatives to synthetic vitamins in livestock nutrition has increased. After a systematic review, a total of 19 peer-reviewed papers published between 2000 and 2020 were retained to evaluate the antioxidant effects of PFA compared to synthetic antioxidant vitamins (mainly vitamin E; VitE) in livestock nutrition. These studies demonstrated that PFAs could be as efficient as VitE in counteracting oxidative stress in pigs, rabbits, and ruminants. However, PFAs only positively affected animals’ growth performance and feed efficiency in some monogastric studies. The PFA can affect antioxidant enzyme activity in a dose- and method of administration-dependent manner. The antioxidant capacity of both PFA and VitE were depressed in cows fed with diets rich in polyunsaturated fatty acids. Variability among studies could be related to species differences. Despite the interest of the feed industry sector in PFA, there are still very few studies evaluating their antioxidant effect in species other than poultry.
|
2022-11-26T06:32:03.311Z
|
205,089,106 |
{
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"ArXiv": null,
"DOI": "10.1111/echo.12675",
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"status": null,
"url": null
}
|
To assess the feasibility and reliability of aortic valve area (AVA) planimetry by means of three‐dimensional transesophageal echocardiography (3DTEE) as compared with the transthoracic echocardiogram (TTE) calculation of AVA, to determine the systematic deviations between measurements, and to describe the distribution of mean systolic in relation with 3DTEE anatomical AVA.
|
2022-12-15T03:01:35.112Z
|
990,225 |
{
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"ArXiv": null,
"DOI": "10.2147/NDT.S12243",
"MAG": "2150541847",
"PubMedCentral": "2987500"
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"status": null,
"url": null
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|
The goal of this study was to determine if impairments detected by the test of variables of attention (TOVA) may be used to predict early attention complaints and memory impairments accurately in a clinical setting. We performed a statistical analysis of outcomes in a patient population screened for attention deficit hyperactivity disorder or attention complaints, processing errors as measured by TOVA and the Wechsler Memory Scale (WMS-III) results. Attention deficit disorder (ADD) checklists, constructed using the Diagnostic and Statistical Manual of Mental Disorders 4th Edition criteria, which were completed by patients at PATH Medical, revealed that 72.8% of the patients had more than one attention complaint out of a total of 16 complaints, and 41.5% had more than five complaints. For the 128 males with a significant number of ADD complaints, individuals whose scores were significantly deviant or borderline (SDB) on TOVA, had a significantly greater number of attention complaints compared with normals for omissions (P < 0.02), response time (P < 0.015), and variability (P < 0.005), but not commissions (P > 0.50). For males, the mean scores for auditory, visual, immediate, and working memory scores as measured by the WMS-III were significantly greater for normals versus SDBs on the TOVA subtest, ie, omission (P < 0.01) and response time (P < 0.05), but not variability or commissions. The means for auditory, visual, and immediate memory scores were significantly greater for normals versus SDBs for variability (P < 0.045) only. In females, the mean scores for visual and working memory scores were significantly greater for normals versus SDBs for omissions (P < 0.025). The number of SDB TOVA quarters was a significant predictor for “impaired” or “normal” group membership for visual memory (P < 0.015), but not for the other three WMS-III components. For males, the partial correlation between the number of attention complaints and the number of SDB TOVA quarters was also significant (r = 0.251, P < 0.005). For the 152 females with a significant number of attention complaints, no significant differences between SDBs and normals were observed (P > 0.15). This is the first report, to our knowledge, which provides evidence that TOVA is an accurate predictor of early attention complaints and memory impairments in a clinical setting. This finding is more robust for males than for females between the ages of 40 and 90 years.
|
2022-12-16T09:08:36.422Z
|
120,796,540 |
{
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"ArXiv": null,
"DOI": "10.1098/rspa.1961.0195",
"MAG": "2006151132",
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"status": null,
"url": null
}
|
A study is made of the motion of the shock wave produced when a piston is impulsively set in motion with constant velocity into a diatomic gas at rest, conditions being such that behind the shock there is a zone of vibrational or dissociational relaxation. The dissociation case is treated by the method of linearized characteristics, using a form for the rate equation due to Freeman (1958), while the vibrational case is included in a discussion in which the third-order equation for acoustic disturbances derived by Chu (1958) is applied to the flow behind the shock. It is shown that in either case the initial speed of the shock is that corresponding to frozen flow between it and the piston, but that the lower speed calculated from equilibrium thermodynamics is approached at large times. Distributions of pressure and velocity between the piston and the shock are found: at long times after the start of the motion these are precisely those given by the Bethe-Teller (1941) theory for partly dispersed shock waves. Some applications to other shock motions are discussed.
|
2022-09-02T21:36:57.942Z
|
45,881,517 |
{
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"DOI": "10.1128/AEM.67.6.2718-2722.2001",
"MAG": "1987324660",
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|
ABSTRACT Methyl iodide (CH3I) plays an important role in the natural iodine cycle and participates in atmospheric ozone destruction. However, the main source of this compound in nature is still unclear. Here we report that a wide variety of bacteria including terrestrial and marine bacteria are capable of methylating the environmental level of iodide (0.1 μM). Of the strains tested, Rhizobium sp. strain MRCD 19 was chosen for further analysis, and it was found that the cell extract catalyzed the methylation of iodide withS-adenosyl-l-methionine as the methyl donor. These results strongly indicate that bacteria contribute to iodine transfer from the terrestrial and marine ecosystems into the atmosphere.
|
2022-12-14T17:04:23.022Z
|
25,252,156 |
{
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"DOI": "10.1111/j.1399-5618.2009.00719.x",
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|
OBJECTIVE
When dissimilar figures are presented to each eye individually, perception alternates spontaneously between each monocular view. This phenomenon, known as binocular rivalry, has been used as a powerful tool to investigate conscious visual awareness. Of clinical relevance, Pettigrew and Miller (Proc Biol Sci 1998; 265: 2141-2148) found slow perceptual alternation rates in patients with bipolar I disorder (BD-I). For a better understanding of differences between BD-I and bipolar II disorder (BD-II), we examined whether perceptual alternation rates of binocular rivalry differ between the two subtypes of bipolar disorder.
METHODS
The subjects comprised 25 healthy controls, 11 patients with BD-I, and 17 patients with BD-II. They underwent binocular rivalry examination. One-way analysis of variance was conducted to determine differences in the phase duration of binocular rivalry between the control, BD-I, and BD-II groups.
RESULTS
Significant differences were observed in the mean phase duration of binocular rivalry between the groups. Although the medication administered did not differ significantly between the BD-I and BD-II patients, the phase duration was significantly longer among the BD-I patients than the BD-II patients and controls, whereas no significant difference was observed in the phase duration between the BD-II patients and controls.
CONCLUSION
The present results reveal a significant difference in the mean phase duration of binocular rivalry between subjects with BD-I and those with BD-II, suggesting the presence of some neurobiological difference between these two subtypes of bipolar disorder.
|
2022-12-29T18:02:04.277Z
|
220,855,599 |
{
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"DOI": "10.1177/007327537701500104",
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"license": null,
"status": null,
"url": null
}
|
9. Karl Pearson, "Old tripos days at Cambridge, as seen from another viewpoint", Mathematical gazette, xx (1936), 27-36, p. 32. 10. James Prescott Joule. On some facts in the science of heat developed since the time of Watt, a lecture delivered to the Greenock Philosophical Society on 19 January 1865 (no place, no date), 14. The only copy of this fifteen page pamphlet of which I am aware is: PA419, Lord Kelvin Manuscript Collection, Add. MS 7342, Cambridge University Library. For discussions by other Christian physical scientists of this general issue, which might be called "Genesis and physics", see Maxwell's letter to the Bishop of Gloucester and Bristol in L. Campbell and W. Garnett, Life of Maxwell (London, 1882), 393-5, and George Gabriel Stokes's and Charles Pritchard's contributions in The expositor, 4th series, iii (1891), 42-53. II. Mary Somerville, On the connexion of the physical sciences (3rd edn, London, 1836), 412. Several Victorian physicists regarded man's mind as having been designed by God, although, so far as I know, they did not actually speak of man's mind as having been created in God's image. For Maxwell, Stokes, P. G. Tait and Kelvin, see my "Kelvin's scientific realism: The theological context", The philosophical journal, xi (1974), 41-60, esp. 52. 12.. For two other discussions of the area of Wallace's thought treated by Turner, see Roger Smith, "Alfred Russel Wallace: Philosophy of nature and man", The British journal for the history of science, vi (1972), 177-99, and Malcolm Jay Kottler, "Alfred Russel Wallace, the origin of man, and spiritualism", Isis, Ixv (1974), 145-92.
|
2022-01-27T11:10:46.798Z
|
56,917,018 |
{
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"DOI": "10.1109/ICSMC.1994.399899",
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A methodology to support design synthesis is described which features intelligent search and generation of alternatives. The search is directed by degree of closeness of multiple responses to their known ideal and imprecise designer preferences. A key objective of the methodology is to minimize the number of probes of the design model which is assumed to be in the form of a simulation program. A multiprocessor system design problem with features representing typical design synthesis problems is presented to demonstrate application.<<ETX>>
|
2022-02-11T18:23:32.277Z
|
250,373,166 |
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"DOI": "10.33119/knop.2022.64.2.4",
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"license": "CCBY",
"status": "GOLD",
"url": "https://econjournals.sgh.waw.pl/KNoP/article/download/2926/2593"
}
|
Niespotykane dotąd tempo zmian w środowisku gospodarczym postawiło przed organizacjami wielkie wyzwania zarówno biznesowe, jak i organizacyjne. Chcąc zwiększać swoją wartość, przedsiębiorstwa muszą z absolutną precyzją wykorzystywać wszystkie swoje zasoby, by sprostać wymogom rynku i akcjonariuszy. Takim zasobem są także działy finansowe, których metamorfoza na przestrzeni ostatnich 25 lat była wręcz spektakularna. Zmieniające się oczekiwania wewnętrznych i zewnętrznych interesariuszy sprawiły, że w ciągu ćwierćwiecza wielu dyrektorów finansowych przeistoczyło się ze strażników budżetu i procedur w strategicznych partnerów biznesowych, aktywnie uczestniczących w procesach decyzyjnych i otwierających nowe szanse przed organizacją. Jednocześnie struktury działu finansów diametralnie zmieniły się, by uwolnić jak najwięcej czasu na aktywności zwiększające wartość dodaną. Celem artykułu jest wskazanie zmian w organizacji działów finansowych oraz kompetencji gwarantujących powodzenie w nowych realiach. Szczególny nacisk jest położony na koncepcję business partneringu, która stanowi i będzie stanowić kluczowy czynnik sukcesu w świecie finansów przedsiębiorstwa. Autor wskaże również kilka potencjalnych kierunków dalszych zmian, które w najbliższych latach będą wpływać na pracę działów finansowych i determinować pozyskiwanie nowych kompetencji.
|
2022-07-10T22:19:47.992Z
|
38,223,424 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1113/jphysiol.1971.sp009658",
"MAG": "1998314398",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1331626"
}
|
1. The ionic mechanism of the action potential produced in lamella‐like muscle cells of amphioxus, Branchiostoma californiense, was investigated with intracellular recording and polarization techniques.
|
2022-09-09T12:16:48.688Z
|
153,115,971 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2139/ssrn.610582",
"MAG": "2952088845",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper argues that there is a trade-off between efficiency and fairness in minority freezeouts and that the focus on fairness (minority shareholder rights) may be misplaced. The model discusses alternative rules for valuing minority shares in freezeouts. Appraisals can be based on the stock price, publicly available information, or private information disclosed by the majority shareholder. Those valuation rules that enhance economic efficiency pay minority shareholders less than what their shares are intrinsically worth. Economic efficiency is worse if minority shareholders extract higher premia in freezeouts. Moreover, all freezeout rules induce inefficient takeovers caused by overbidding. Bidders overpay for some shares in order to obtain a valuable freezeout option, which sometimes remains unexercised. The real problem is the freeze-in problem, as minority shareholders are left with lower-valued shares. Efficiency can be restored through a mandatory bid rule.
|
2022-09-14T16:45:07.555Z
|
224,828,862 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/1073858420966276",
"MAG": "3094139868",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Evidence from preclinical and clinical research suggest that neuromodulation technologies can facilitate the sublesional spinal networks, isolated from supraspinal commands after spinal cord injury (SCI), by reestablishing the levels of excitability and enabling descending motor signals via residual connections. Herein, we evaluate available evidence that sublesional and supralesional spinal circuits could form a translesional spinal network after SCI. We further discuss evidence of translesional network reorganization after SCI in the presence of sensory inputs during motor training. In this review, we evaluate potential mechanisms that underlie translesional circuitry reorganization during neuromodulation and rehabilitation in order to enable motor functions after SCI. We discuss the potential of neuromodulation technologies to engage various components that comprise the translesional network, their functional recovery after SCI, and the implications of the concept of translesional network in development of future neuromodulation, rehabilitation, and neuroprosthetics technologies.
|
2022-09-27T21:23:55.096Z
|
251,777,356 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/sci4030032",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.mdpi.com/2413-4155/4/3/32/pdf?version=1661160065"
}
|
We report high-level ab initio calculations (CCSD(T)(full)/CBS//SCS-RI-MP2(full)/aug-cc-pwCVTZ) that demonstrate the importance of cooperativity effects when Anion–π and CH/π interactions are simultaneously established with benzene as the π-system. In fact, most of the complexes exhibit high cooperativity energies that range from 17% to 25.3% of the total interaction energy, which is indicative of the strong influence of the CH/π on the Anion–π interaction and vice versa. Moreover, the symmetry-adapted perturbation theory (SAPT) partition scheme was used to study the different energy contributions to the interaction energies and to investigate the physical nature of the interplay between both interactions. Furthermore, the Atoms in Molecules (AIM) theory and the Non-Covalent Interaction (NCI) approach were used to analyze the two interactions further. Finally, a few examples from the Protein Data Bank (PDB) are shown. All results stress that the concurrent formation of both interactions may play an important role in biological systems due to the ubiquity of CH bonds, phenyl rings, and anions in biomolecules.
|
2022-10-03T16:52:34.561Z
|
22,486,419 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1067/MNC.2002.122630",
"MAG": "2074240574",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The initial evaluation of patients presenting to emergency departments with chest pain of suspected cardiac origin is critical in determining hospital admission or discharge. Clinical evaluation alone has been unsatisfactory as a complete triage tool in this setting. This has resulted in numerous unnecessary hospital admissions, as well as unfortunate hospital discharge of patients with coronary artery disease. The situation has become more critical as hospitals, particularly in large metropolitan centers, are above capacity, resulting in closing of hospital admitting and emergency departments to critically ill patients. Acute rest myocardial perfusion imaging has been clearly documented as an extremely useful tool in the evaluation of such patients. However, uniform standards have been lacking. This position statement by an American Society of Nuclear Cardiology task force on chest pain centers clearly demonstrates the value of acute rest myocardial perfusion imaging in the triage of patients with suspected acute coronary syndromes. The document further elucidates steps necessary for such evaluation and the type of patients for whom this evaluation is best suited. As such, the document furthers our appreciation of acute rest myocardial perfusion imaging in the emergency setting.
|
2022-12-03T23:42:19.770Z
|
153,510,192 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/00220480903382222",
"MAG": "2013117723",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The authors shed light on the original equipment manufacturer's strategic behavior in the duopoly aftermarket. The original equipment manufacturer, firm 1, captures via its foremarket price some fraction of the aftermarket consumer surplus, where that surplus is generated by consumption of its own and its competitor's aftermarket products. The other firm, firm 2, only operates in the aftermarket and does not capture any of the aftermarket consumer surplus. Assuming a Cournot or Stackelberg duopoly aftermarket with firm 1 as the quantity leader, we find the conditions under which firm 1's aftermarket price is above or below its marginal cost; the conditions under which firm 1's profit falls or increases when firm 2 adds value to its aftermarket product or lowers its marginal cost; and the conditions under which firm 1 is less profitable or more profitable in sharing the aftermarket than it would be alone.
|
2022-02-09T02:18:54.134Z
|
147,064,581 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1590/S0103-49792016000100012",
"MAG": "2337119529",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Para o filosofo hungaro Istvan Mesza-ros, algumas novas questoes se colocaram como fundamentais na contemporaneidade: o que deve ser feito e o que pode ser feito nes-sa conjuntura da historia no que diz respeito aos grandes problemas do Estado? O Estado, tal qual foi constituido historicamente, e mes-mo capaz de resolver todos os nossos graves problemas, ou o Estado, como tal, tornou-se um dos principais contribuintes para o agrava -mento de seus proprios problemas e para sua insolubilidade cronica? Quais sao os requisi-tos de uma alternativa radicalmente diferente? Existem quaisquer perspectivas viaveis para o futuro, caso uma forma substancialmente di-ferente de controlar o metabolismo social nao possa ser instituida em oposicao a preponde-rância das perigosas determinacoes do Estado em falencia [failing state]? Existe uma saida do circulo vicioso ao qual estamos confinados pelo capitalismo do seculo XXI?Essas sao as questoes de Meszaros, ven-cedor do Deutscher Memorial Prize, em 1970. Neste seu A montanha que devemos conquis-tar: reflexoes acerca do Estado, e sobre essa estrutura institucional, configurada como espaco da disputa capitalista, que o autor se debruca para nos surpreender com sua solu-cao: erradica-la por completo. Para Meszaros, vive-se o momento do “Estado em falencia” e urge sua substituicao por uma nova “ordem so -ciometabolica”. A construcao de sua tese parte dos grandes teoricos do Estado (de Hobbes a Bobbio). Essa linha de raciocinio, na verdade, comecou no cartapacio Para alem do capital (da mesma editora, 1.104 p.), obra na qual in-troduziu a reflexao sobre como poderia o Esta-do fenecer (o capitulo e, inclusive, republica-do neste novo livro como apendice, junto com uma entrevista concedida a imprensa). Meszaros segue sua analise, obviamen-te, com uma revisita as solucoes alternativas surgidas no campo marxista, como o regula-cionismo e o derivacionismo, consideradas por ele como incompletas. Embora critico, Meszaros rejeita a acusacao de que esse cam-po defenderia uma “anarquia utopica sem lei” ou que os socialistas de hoje desejariam “a transformacao da nossa inevitavel modalidade global de reproducao social em algum tipo de comunidade utopica de vila bucolica”.O diagnostico de Meszaros e que, no ca-pitalismo do nosso seculo, “a Lei”, base da or-ganizacao regulatoria do Estado, funciona “de fato” somente ao afirmar-se como forca – ou “lei do mais forte”. No âmbito da tomada de decisao politico-militar global, no dominio das relacoes interestatais, o Estado assume, assim, uma afirmacao mais violenta possivel dos in-teresses das forcas em conflito. A tese remete ao novo momento das relacoes entre Estados Unidos e Cuba, depois de mais de meio se-culo de embargo a ilha de Fidel Castro, como nesse trecho: “[...] a lei se impoe ao decretar categoricamente a viabilidade constitucional de si mesma em sua simbiose com a relacao estabelecida de forcas, continua a fornecer sua legitimacao pelo Estado com a mesma afirma-cao categorica enraizada na forca, ate que haja uma grande mudanca na relacao das proprias forcas. Assim, a proclamacao constitucional e imposicao juridicamente incontestavel da ‘lei do mais forte’ pode continuar, tanto se for fei-ta da maneira ditatorial mais cruel ou com o ‘rosto sorridente’ das formacoes estatais libe-ral-democraticas do sistema do capital. Mas, apesar de todas as tentativas de eternizacao a-historicas do Estado, a imposicao da ‘lei do mais forte’ sobre a sociedade nao pode conti-nuar para sempre. A hora da verdade chega
|
2022-02-09T05:36:32.895Z
|
240,954,206 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1145/3359852.3359949",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
My childhood memory album is filled with pictures of severed arms. There are many black and white photographs of me as an infant being cradled by a pair of arms that are unattached from their owner's body. There are pictures of these disembodied arms holding me in the pool, at the zoo, and carrying me into the small brick house we called home on the Marine's military base in Santa Ana, California. For a while, every memory I had of my father brought to mind the image of his severed arms: arms that had been violently ripped from his body in a moment of anger. When my father was killed in Vietnam in 1967, my mother reacted in anger, furious at being abandoned and left alone with three young children. I believe she was angry at the unfinished business of their Jives, the future that once was so carefully planned now hanging in shreds like laundry left out in a violent storm. The potential of their lives gone in one instant, left with nothing but fear and anger at the incompleteness oftheir life together. In her anger, she sat in the living room in front of an intense roaring fire and stared at her favorite photographs. Then, in deliberate motions of rage, she carefully tore his image from every picture she had, leaving only his arms. There was a controlled fury to this motion, for she knew she couldn' t totally destroy the pictures. Destruction would erase our existence, while this mutilation only altered it. I came to know these arms well, and would dream often of his body crying out for his lost appendages. Bits and pieces of his body were all that were returned to my mother, and bits and pieces summed up the heritage she left for us. I remember several weeks after his death when I couldn't find a picture that he had sent me of himself in uniform. I was frantic and when I finally found it, ran into my mother's bedroom to show her. I recall her form as she was bending over pulling her pantyhose up over her knees, and I recall her shocked expression when I burst into
|
2022-07-07T12:20:50.355Z
|
55,521,058 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.37936/ecti-eec.200862.171774",
"MAG": "2099813860",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "HYBRID",
"url": "https://ph02.tci-thaijo.org/index.php/ECTI-EEC/article/download/171774/123337"
}
|
The ion implantation based impurity doping profile across a p-n junction can be represented accurately using Pearson's fourth moment approach. The high-frequency characteristics of the reverse biased p-n junction (IMPATT diodes) are computed using different ion implantation profiles. It has been observed that the microwave properties of IMPATT diodes are very sensitive to the change in doping profiles. The optimized ion implantation profiles are suggested for different frequency bands to fabricate the reverse biased p-n junction for application in high-frequency circuits.
|
2022-09-14T00:12:19.451Z
|
130,580,326 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.18636/BIODESARROLLO.V26I2.483.G493",
"MAG": "17792020",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In the municipality of Quibdo use pools as a means of recreation and healthy entertainment is widespread; evaluated environmentally 10 pools for public use to which they made direct observation and surveys collect information that allowed for the general description; were taken 12 samples per pool for physico-chemical and microbiological analysis to determine water quality. The 100% of the pools do not have qualified personnel for the treatment of water, do not receive visits from health officials responsible for oversight and control; for lack of preventive and corrective maintenance outside service equipment (pumps and filters) for water treatment; all the pools presented coliform contamination and fungi. The values of residual chlorine and pH, are not within the range established by the regulations (Resolution No 2191 of 1991), these being the values most important in the treatment of water from the pools.
|
2022-02-09T14:08:33.618Z
|
22,302,997 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/VTCF.2006.28",
"MAG": "2150950015",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Knowledge of the Ricean K-factor is important for accurate assessment and simulation of wireless channels, particularly those in which both terminals are stationary and a strong line-of-sight or fixed component exists. While previous work has focused on development of novel K-factor estimators, the practical matter of determining the minimum number of samples N (or minimum sample duration T) required to estimate K to within a specified confidence interval sigmaK has not received much attention. Here, for the case of a simple moment-based K-factor estimator, we use Monte Carlo simulations to show how N and T depend upon the value of K, the confidence interval sigmaK, the correlation between successive samples, and the sampling interval DeltaT. The results will be useful to those who use such an estimator in practical systems for the purposes of channel state estimation and/or radio resource management.
|
2022-03-05T21:45:28.703Z
|
161,057,390 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.20435/PSSA.V6I1.327",
"MAG": "1533102224",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A qualidade de vida e de suma importância para a saude do individuo, porem ela depende de muitos fatores,
dentre eles destaca-se o trabalho. Desse modo, este artigo trata-se de uma pesquisa transversal de abordagem
quantitativa-descritiva, com objetivo de avaliar a qualidade de vida de tecnicos de enfermagem de um hospital
filantropico de grande porte, localizado no municipio de Dourados-MS. A amostra foi composta de 73 funcionarios
de ambos os sexos. Aplicou-se um questionario sociodemografico e o WHOQOL-Bref. Foi constatado que 76,9%
dos participantes sao mulheres, a idade media foi 36,4 anos. Na amostra, 50% consideraram ter uma boa qualidade
de vida e 80% estao satisfeitos com sua saude. A pontuacao no WHOQOL-Bref, por dominio foi: fisico = 73,8,
psicologico = 72,6, social = 71,6 e ambiental = 56,2. Conclui-se que os tecnicos de enfermagem possuem boa
qualidade de vida.
Palavras-chave: Qualidade de vida; Enfermagem; Pessoal de saude.
|
2022-05-30T23:44:46.447Z
|
233,907,035 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1117/12.2581883",
"MAG": "3132039706",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Understanding repeatability of classification by classifier in the context of overall classification performance and operating points can contribute to improved design of computer-aided diagnosis (CADx). Breast lesions (243 benign, 853 malignant: 1,096 total) were segmented using a fuzzy c-means method from dynamic contrast-enhanced magnetic resonance images acquired over 2005-2015. Thirty-eight radiomic features were extracted. Overall classification performance, case-based classification repeatability, and attainment of ‘preferred’ target and ‘optimal’ sensitivity and specificity were investigated for three classifiers: linear discriminant analysis, support vector machine, and random forest using a 1000-iteration 0.632 bootstrap. The area under the receiver operating characteristic curve (AUC) for the task of classifying lesions as malignant or benign was determined using the 0.632+ bootstrap correction. AUC was compared between classifiers; statistical significance was indicated when the 98.33% confidence interval (CI) of the difference in AUC (corrected for multiple comparisons) excluded zero. Classifier repeatability was determined through 95% CI width of classifier output by case across classifier output range. Classifier output thresholds were determined from the training folds for target sensitivity (95%), target specificity (95%), and for a selected ‘optimal’ operating point determined by minimizing (1-sensitivity)2 + (1-specificity)2 and applied to the test folds. No difference in AUC was observed between the three classifiers. Classifier output, however, was more repeatable when the random forest classifier was used as indicated by a lower 95% CI width of classifier output overall. Moreover, limited differences by classifier in threshold to attain target and ‘optimal’ sensitivities and specificities along with attained sensitivities and specificities were observed. CADx design may benefit from these considerations when selecting which classifier is used.
|
2022-05-26T13:43:18.538Z
|
221,619,462 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1039/d0sm01337d",
"MAG": "3083828057",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We present a theoretical approach for calculating the state of stress induced by a uniform magnetic field in confined magnetoactive elastomers of arbitrary shape. The theory explicitly includes the magnetic field generated by magnetizable spherical inclusions in the sample interior assuming a non-linear magnetization behavior. The initial spatial distribution of particles and its change in an external magnetic field are considered. This is achieved by the introduction of an effective demagnetizing factor where both the sample shape and the material microstructure are taken into account. Theoretical predictions are fitted to the stress data measured using a specifically designed experimental setup. It is shown that the theory enables the quantification of the effect of material microstructure upon introducing a specific microstructural factor and its derivative with respect to the extensional strain in the undeformed state. The experimentally observed differences between isotropic and anisotropic samples, compliant and stiff elastomer matrices are explained.
|
2022-11-19T18:05:01.541Z
|
53,025,844 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/evj.13032",
"MAG": "2898576265",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
BACKGROUND
Control of equine infectious anaemia (EIA) currently depends on serological diagnosis of infected equids. However, recently infected equids may not produce detectable anti-EIAV antibodies up to 157 days post infection and so present a high transmission risk. Therefore, direct nucleic acid detection methods are urgently needed to improve EIAV surveillance and management programs in counties where the disease is endemic.
OBJECTIVES
To evaluate a field-deployable, reverse transcription-insulated isothermal PCR (RT-iiPCR) assay targeting the conserved 5' untranslated region (5' UTR)/exon 1 of the tat gene of EIAV.
STUDY DESIGN
The analytical and clinical performance of the newly developed EIAV RT-iiPCR was evaluated by comparison with a EIAV real-time RT-PCR (RT-qPCR) along with the AGID test.
METHODS
Analytical sensitivity was determined using in vitro transcribed RNA containing the target area of the 5' UTR/tat gene and samples from two EIAV-positive horses. Specificity was verified using nine common equine viruses. Clinical performance was evaluated by comparison with EIAV RT-qPCR and AGID using samples derived from 196 inapparent EIAV carrier horses.
RESULTS
EIAV RT-iiPCR did not react with other commonly encountered equine viruses and had equivalent sensitivity (95% detection limit of eight genome equivalents), with a concordance of 95.41% to conventional EIAV RT-qPCR. However, the RT-qPCR and RT-iiPCR had sensitivities of 43.75 and 50.00%, respectively, when compared to the AGID test.
MAIN LIMITATIONS
Low viral loads commonly encountered in inapparent EIAV carriers may limit the diagnostic sensitivity of RT-PCR-based tests.
CONCLUSIONS
Although EIAV RT-iiPCR is not sufficiently sensitive to replace the current AGID test, it can augment control efforts by identifying recently exposed or "serologically silent" equids, particularly as the latter often represent a significant transmission risk because of high viral loads. Furthermore, the relatively low cost and field-deployable design enable utilisation of EIAV RT-iiPCR even in remote regions.
|
2022-11-18T17:34:12.510Z
|
149,559,405 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.20870/OENO-ONE.2019.53.2.2420",
"MAG": "2940584297",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Aims: Climate change imposes increasingly warm and dry conditions in most winegrowing regions. Mediterranean vineyards are particularly vulnerable and have registered, in most situations, declining yields over the past years. Although a majority of Mediterranean vineyards are still dry-farmed, yields can be increased by the implementation of irrigation. However, irrigation has an impact on increasingly affected water resources. An alternative solution to irrigation can be the adaptation of training systems. As can be shown by water balance modeling, low density non-irrigated vineyards are much less vulnerable to climatic drought compared to medium or high density vineyards. And while yields tend to be lower in low density vineyards, so are production costs. The aim of this study is to investigate to what extent low density vineyards can be a sustainable and cost effective adaptation for grape growing in dry climates.Methods and results: A water balance model was applied to conceptual vineyards with different soil water holding capacities and different planting densities over recent past (1981-2010) and near future (2041-2070) climatic conditions for two winegrowing scenarios (Cabernet-Sauvignon in Bordeaux and Grenache in Avignon, Côtes du Rhône). Row spacings of 2.0, 3.0 and 4.0 m were investigated for vineyards with 100, 200 and 300 mm total transpirable soil water (TTSW), while inter-vine spacing, vine architecture, and canopy height were kept similar. Projected yields were estimated to vary according to vine density and water deficit based on a meta-analysis of data published in the literature. Production costs were calculated according to an operation-based costing methodology and compared among the different scenarios on a cost per hectare basis. Gross profit per hectare, defined as grape sales revenue minus production costs, was then computed for two grape sale revenue scenarios (1 €/kg and 3 €/kg). The modeled average fraction of transpirable soil water (FTSW) varied across the different winegrowing scenarios, climate periods (recent past or near future), and TTSW and row spacing assumptions. In soils with 200 or 300 mm TTSW, the 30-day average FTSW prior to modeled grape harvest roughly doubled when 4.0 m versus 2.0 m spacing was assumed in both the recent past and near future climate scenarios. In soils with 100 mm TTSW, water deficit was more severe overall and the effect of row spacing on average FTSW was less pronounced. Changes in projected yields were estimated as a function of vine density and FTSW based on relationships published in the literature. Yields decreased with decreasing vine density and increasing water deficits, while production costs decreased with decreasing vine density. When the assumed revenue from grape sales was lower (1 €/kg), the effect of reduced production cost savings outweighed the loss in revenue caused by reduced yields, leading to increased gross profit per hectare. On the other hand, when higher grape revenue was assumed (3 €/kg), the effect of reduced yield on revenue outweighed the associated reduction in production costs, leading to reduced gross profit per hectare.Conclusions: Lower density, dry-farmed vineyards will experience less water deficit under warmer and drier climate conditions, although this difference is less pronounced in soils with less water holding capacity. When considering differences in yields, revenues, and production costs, lower density vineyards producing lower value grapes (1 €/kg) may also experience an associated increase in gross profit, while such vineyards producing higher value grapes (3 €/kg) might experience a decrease in gross profit.Significance and impact of the study: The implementation of dry-farmed, low density vineyards provides a sustainable solution for grape growing by reducing the need for irrigation water. It allows maintaining vineyards in very dry areas where water is not readily available for irrigation and where other crops (except possibly olive trees) cannot be grown. Modeling of yield, revenue, and production costs shows that this solution is also economically viable, particularly for vineyards producing lower value (€/kg) grapes. Unlike goblet trained bush vine, low density trellised vineyards are perfectly adapted for mechanization.
|
2022-12-27T16:48:05.366Z
|
43,735,362 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/jf304881g",
"MAG": "1963710289",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Red fermented rice is used worldwide by many patients as an alternative therapy for hyperlipidemia; however, the discovery of a toxic fermentation byproduct, citrinin, causes much controversy about the safety of red mold rice products. A new and fast high-performance liquid chromatography method was developed and validated for simultaneous determination of cholesterol-lowering compounds monacolin K (lovastatin), monacolin K hydroxy acid, and other monacolins present in red fermented rice as well as nephrotoxic mycotoxin citrinin in a single run using connected diode array and fluorescence and mass spectrometric detectors. The proposed method was successfully applied for the analysis of red fermented rice food samples and various dietary supplements also containing other natural lipid-lowering agents. The deviations between label content and levels of active compounds found in investigated samples as well as high batch-to-batch variation found in one product indicate that the regular quality control of red fermented rice products is of great importance.
|
2022-12-27T20:46:46.127Z
|
236,365,539 |
{
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"DOI": "10.3233/BHR210006",
"MAG": "3165164920",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Stem cells used in therapy include mainly hematopoietic stem cells (HSC) to treat aplasias, leukemias and hematological genetic diseases, and mesenchymal stem cells (MSC) produced in small quantities by the bone marrow, but also other tissues, to treat cardiac and cutaneous diseases thanks to their secretory properties of growth factors. A major step was taken with the use of embryonic (ESC) or induced pluripotent stem cells (iPS). The former are used, after isolation and differentiation, either in rare therapeutic purposes or for the in vitro screening of drugs. iPS are produced from adult cells after reprogramming and differentiation and utilized for the treatment of various diseases in autologous or allogeneic form, the second condition allowing only mass production. New lines of research are now in progress including the creation of organoids that are templates of many organs of the body and allow the process of cell organization and its perturbations to be analyzed. Creation of post-meiosis gametes (23 chromosomes) from iPS or ESC is intended to treat serious genetic diseases. Creation of human chimera by interspecies blastocyst complementation has also been studied in view of organ transplantation. It is only allowed for the implantation of human cells in animal blastocysts and prohibited for the reverse. Implantation in uterus of the modified embryos is prohibited by the French law.
|
2022-01-27T10:25:21.523Z
|
146,961,428 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/1541931214581065",
"MAG": "2329906514",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper presents initial insights from an exploratory analysis of human decision making in a human—robot teaming scenario. A cognitive model in the form of a decision tree was developed using local and national police foot pursuit protocols. Participants were asked to read through a series of hypothetical scenarios involving a Soldier and a robot engaging in a foot pursuit of a person of interest. Participants made decisions at each node of the decision tree and then a tactical decision concerning which member of the team should engage in the pursuit. Initial results revealed that individual decision nodes were not associated with participants’ choice in who should engage in the pursuit. Trust in robots, however, was significantly associated with the participants’ choices.
|
2022-07-29T11:59:59.902Z
|
246,588,267 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.12688/mep.18938.2",
"MAG": null,
"PubMedCentral": "9370088"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://doi.org/10.12688/mep.18938.2"
}
|
Background: This paper describes the development of a culturally competent medical humanities course for second and third-year medical students at the ethnically diverse College of Medicine at Qatar University. First taught in 2016, the elective seminar “Medicine and the Arts” was restructured in 2017 to cultivate an appreciation of the symbiotic relationship between medicine, art, and humanities, and to foster cultural competence among the students. Methods: Results and tips are based on our experiences and past reports. Results: In designing a course for students immersed in an Arab-Muslim context, we encountered two challenges: the discipline’s privileging of a predominantly Western canon of arts and humanities, and the largely Euro-American-centric and unilateral framing of concepts e.g., the doctor-patient relationship, patient-centered approach, patient experiences, and meanings of health and illness. To circumvent these challenges, we followed the Purnell Model for Cultural Competence, adopted the interdisciplinary approach, and employed an intersectionality framework to build and deliver a culturally competent course exploring the nexus of arts, humanities, and medicine. In addition to these tips on which frameworks to adopt and how to structure the course, we recommend a visual literacy workshop to help them develop the ability to recognize and understand ideas conveyed through art. Furthermore, we recommend deep conversations about artistic portrayals of medicine from different cultural contexts as tools for developing cultural awareness. Lastly, we recommend that these discussions adopt a student-centered approach, where students inform about their experiences and their own health and illness determinants, in order to develop their knowledge and practice of holism and patient centered approach, and other issues related to humanities and social sciences. Conclusions: Adopting and implementing a culturally competent approach to medical education, alongside interdisciplinary and intersectionality concepts, are potential conceptual frameworks to structure a course that uses art to inform about medical humanities.
|
2022-10-14T00:40:41.192Z
|
17,499,529 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.5565/REV/ELCVIA.96",
"MAG": "2166196972",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper presents a multi-classifier system design controlled by the topology of the learning data. Our work also introduces a training algorithm for an incremental self-organizing map (SOM). This SOM is used to distribute classification tasks to a set of classifiers. Thus, the useful classifiers are activated when new data arrives. Comparative results are given for synthetic problems, for an image segmentation problem from the UCI repository and for a handwritten digit recognition problem.
|
2022-11-28T18:15:23.272Z
|
248,054,745 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.9734/ajess/2022/v27i130648",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
Aims: To determine the saving and spending attitudes of college students.
Study Design: Descriptive and semi-quantitative.
Place and Duration of Study: Malita, Davao Occidental, Philippines during the first semester of 2019-2020
Methodology: The respondents of the study were chosen using the Slovin formula. One hundred thirty-three college students were involved. Data were gathered through an adapted survey questionnaire.
Results: Generally, the mean age of the respondents was 20.54. Most of them were female. The respondents saved money regularly for emergency use. Their parents were their usual source of money and they kept their savings in the piggy bank. The money they obtained was commonly spent on school projects. Others did not have savings due to lack of money. Only few of the respondents deposited their savings in the banks. It was also found that age determined the saving attitude. Conversely, if considered individually, saving attitude had no significant difference with gender and marital status but when grouped together, saving attitude had significant difference with gender and marital status. It implicated that saving money should be introduced early among the children.
|
2022-12-02T10:18:08.348Z
|
113,096,705 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5755/J01.MECH.22.1.11420",
"MAG": "2300278658",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Annular seal is one of the important factors influencing the dynamic vibration property of multi-stage pumps. In order to research the vibration characteristics of multi-stage pumps, a coupling vibration model of multi-stage pump rotor system, including the coupling effects of bearings and short annular seals dynamic coefficients, was developed based on Finite Element Method (FEM) and Lagrange equation. A model rotor was investigated to verify the numerical results of the coupling vibration model. Based on the coupling vibration model, the first critical speeds of the model rotor system were analyzed under different seal drop pressures and radius seal clearances. The experimental results of the model rotor showed good agreement with the calculated results and smaller calculation error compared with the previous model. The coupling model provides an effective method for the research of multi-stage pump rotor system. DOI: http://dx.doi.org/10.5755/j01.mech.22.1.11420
|
2022-12-07T21:51:06.100Z
|
49,195,583 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1145/3243734.3243851",
"MAG": "2891311364",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "http://dl.acm.org/ft_gateway.cfm?id=3243851&type=pdf"
}
|
We explore a new security model for secure computation on large datasets. We assume that two servers have been employed to compute on private data that was collected from many users, and, in order to improve the efficiency of their computation, we establish a new tradeoff with privacy. Specifically, instead of claiming that the servers learn nothing about the input values, we claim that what they do learn from the computation preserves the differential privacy of the input. Leveraging this relaxation of the security model allows us to build a protocol that leaks some information in the form of access patterns to memory, while also providing a formal bound on what is learned from the leakage. We then demonstrate that this leakage is useful in a broad class of computations. We show that computations such as histograms, PageRank and matrix factorization, which can be performed in common graph-parallel frameworks such as MapReduce or Pregel, benefit from our relaxation. We implement a protocol for securely executing graph-parallel computations, and evaluate the performance on the three examples just mentioned above. We demonstrate marked improvement over prior implementations for these computations.
|
2022-12-16T18:01:05.066Z
|
16,615,425 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1142/S0218001408006326",
"MAG": "1999280378",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The biometric verification task is to determine whether or not an input and a template belong to the same individual. In the context of automatic fingerprint verification the task consists of three steps: feature extraction, where features (typically minutiae) are extracted from each fingerprint, scoring, where the degree of match between the two sets of features is determined, and decision, where the score is used to accept or reject the hypothesis that the input and template belong to the same individual. The paper focuses on the final decision step, which is a binary classification problem involving a single score variable. The commonly used decision method is to learn a score threshold from a labeled set of inputs and templates, by first determining the receiver operating characteristic (ROC) of the task. The ROC method works well when there is a well-registered fingerprint image. The paper shows that when there is uncertainty due to fingerprint quality, e.g. the input is a latent print or a partial print, the decision method can be improved by using the likelihood ratio of match/non match. The likelihood ratio is obtained by modeling the distributions of same finger and different finger scores using parametric distributions. The parametric forms considered are Gaussian and Gamma distributions whose parameters are learnt from labeled training samples. The performances of the likelihood and ROC methods are compared for varying numbers of minutiae points available for verification. Using either Gaussian or Gamma parametric distributions, the likelihood method has a lower error rate than the ROC method when few minutiae points are available. Likelihood and ROC methods converge to the same accuracy as more minutiae points are available.
|
2022-12-20T10:13:10.768Z
|
144,610,245 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1353/sho.1997.0055",
"MAG": "2047582426",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
of "ethical hermeneutics," and his careful, respectful, and impassioned readings of Levinas and Rosenzweig can certainly serve as our models. There are also questions for which Cohen's text does not prepare us. One such question is, in light of the elevation of the Other for both Levinas and Rosenzweig, how do we read their "others"? Levinas's others include Derrida and feminism. But Cohen's treatment of these others is anything but ethical. Feminist critics of Levinas, many of whom have deep sympathies with his work, are dismissed by Cohen as having an "agenda" (cf., p. 195, n. 1). Derrida, while given more careful consideration than the feminist critics, is clearly considered "the enemy" in Cohen's concluding chapter. While Cohen's interests are clearly in defending Levinas's thought, one would do well to pause and consider Levinas's others from a position more dignified than the excluded enemy. For, as Cohen himself repeats, the task that lies before us in the wake ofboth Levinas and Rosenzweig concerns not textual/conceptual territory, but the concrete, infmite work of ethics. This extends to Levinas and Rosenzweig, as well as their (and inevitably our) others. John E. Drabinski Department of Philosophy University of Memphis
|
2022-02-09T06:52:58.979Z
|
30,315,515 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1542/peds.11.5.480",
"MAG": "1908304078",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Three cases of idiopathic hyperlipemia with associated sicklemia in siblings are reported. One case was treated with ACTH and one with cortisone neither of which had any apparent lasting effect upon the disease.
|
2022-09-12T21:39:21.225Z
|
126,467,690 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/0959683615594473",
"MAG": "858889679",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The Special Issue provides a deep-time interdisciplinary perspective on the Anthropocene and signals the importance of the Anthropocene concept in past, present, and future human–environmental relationships. This concluding article recognizes that various approaches – scientific, postmodern, catastrophist, and ecomarxist – can contribute to understanding the Anthropocene as a process and that contributions have been made by several disciplines, including Anthropology, Archaeology, Geography, History, and Politics. The critical importance of weaving together social science perspectives with those of the natural sciences is emphasized.
|
2022-11-01T14:19:57.548Z
|
36,208,141 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ITEC-AP.2014.6940989",
"MAG": "2313878919",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The resonant coils are the significant part of the whole wireless power transfer system. The magnetic field leakage will cause the human exposure to time-varying electromagnetic fields problems and low coupling coefficient. In this paper, a 3D model is established to simulate the magnetic field. A new shielded structure is proposed in this paper. A comparasion of the magnetic field between shielded structure and unshielded structure is presented in this paper. An experiment of 8kw and 10kw wireless power transfer system are established in this paper. And as the results of simulation and experiment, the new shielded structure achieve the higher coupling coefficient and suppress the magnetic field leakage.
|
2022-12-09T11:58:31.150Z
|
142,752,477 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1108/QRJ-07-2013-0043",
"MAG": "1533134180",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Purpose – Taking Community Design Centers (CDC) in the USA as case studies, the purpose of this paper is to investigate the impact of a type of service learning increasingly found in colleges of architecture. Typically, the CDC is a model of architecture's civic engagement that makes claims to “give back” to under-served communities and enhance student learning with applied architectural design work. Design/methodology/approach – This project is part of a long-term engagement as participant observer and ethnographer in the field of architecture. Fieldwork in this investigation is presented as four case studies in separate and specific contexts. Findings – Initial findings suggest there are conflicting intentions and aspirations at work through service learning in architecture and its implementation calls into question who or what is served. The author argues architecture's epistemology, pedagogical structure, and ideology precludes effective civic engagement. Originality/value – The value of this research...
|
2022-12-12T16:51:34.753Z
|
234,611,405 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.37295/WP.V14I01.38",
"MAG": "3119982144",
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},
"license": null,
"status": null,
"url": null
}
|
Wacana pemberdayaan ekonomi masyarakat melalui pemanfaatan program CSR/PKBL BUMN bukan sesuatu hal yang baru. PT.Telkom sangat menaruh perhatian terhadap pengembangan UKM, mengingat UKM merupakan tulang punggung pertumbuhan perekonomian nasional. Namun UKM menghadapi kendala modal, perdagangan dan kompetensi. Tanggung jawab sosial perusahaan (CSR) oleh PT. Telkom dijadikan sebagai bagian dari strategi bisnis perusahaan, melalui Program Kemitraan dan Bina Lingkungan (PKBL). Kegiatan ini dilakukan dalam berbagai bentuk, antara lain berupa pemberdayaan ekonomi masyarakat. Artikel ini bertujuan memberikan gambaran upaya yang dilakukan oleh PT. Telkom dalam pemberdayaan UKM berbasis digital.
|
2022-12-12T22:46:58.404Z
|
246,698,622 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.31983/micajo.v1i2.5547",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://ejournal.poltekkes-smg.ac.id/ojs/index.php/micajo/article/download/5547/1511"
}
|
Teenagers often experience problems related to sexuality or reproductive health. A lot of information through the means of the print, electronic broadcast is vulgar and not educational, but more likely to influence and encourage irresponsible sexual behavior. The design of this study uses analytic surveys with cross sectional approaches. The population is class XI students, amounting to 225 students. The research sample of 70 respondents. The sampling technique uses simple random sampling. The type of analysis used is univariate, bivariate and Chi Square test. The research instrument used a questionnaire that was previously tested for validity and reliability. The results of this study showed that most students were exposed to pornography on the internet with a total of 48 students (68.6%). And positive teen dating attitudes 58 students (82.9%). From the results of this study, the p value was 0.013 0.05. This study concluded that there was a relationship between pornography exposure on the internet and the attitude of adolescent dating in class XI at SMK NU 02 Rowosari. It is expected that adolescents should increase knowledge about reproductive health and enhance positive activities. The teachers put more emphasis on moral education so that students avoid the negative effects of exposure to electronic or internet facilities that deviate and avoid the negative effects of bad dating behavior.
|
2022-02-25T00:31:27.247Z
|
248,985,783 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/jep.13704",
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},
"license": null,
"status": null,
"url": null
}
|
RATIONALE
Question Storming offers a method that enables one to hold the condition of uncertainty in reflection without the need for resolution. Global interdependencies and unprecedented access to information, social media and multiple forms of communications challenge our ability to see, understand and influence change effectively and efficiently. The tension and need to cope effectively with massive uncertainties cannot be resolved with current methods leading to a necessity for people to seek new ways to transform their understanding and explore new options for action. Problem-solving and facilitation of the past are not flexible or rapid enough to meet the current demands of decision making and action taking in the face of massive uncertainties. As a result, people face 'wicked unsolvable' issues in their personal and professional lives.
AIMS AND OBJECTIVES
An international group of scholar-practitioners has adapted and tested an enquiry process. Question Storming-The Power of Questions is based on principles of complex adaptive systems, human systems dynamics, and self-organization.
METHOD
A three-step method of inquiry and reflection opens new possibilities.
RESULTS AND CONCLUSIONS
Question Storming has helped people see their wicked issues from new perspectives, understand them in useful ways and generate new options for action. This paper introduces Question Storming-the Power of Questions as a practical method for group inquiry in the presence of individual and group uncertainties/wicked issues. The Container, Difference, Exchange (CDE) model and Pattern Logic are presented to explain the paradigm-shifting dynamics experienced by participants, both individuals and members of the group. It concludes with emerging questions for future consideration. Question Storming generates a divergent problem space that decreases constraint and increases degrees of freedom to allow practical exploration of new and often surprising options for action.
|
2022-05-25T15:53:39.120Z
|
140,134,235 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.9753/ICCE.V32.STRUCTURES.35",
"MAG": "1973665481",
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},
"license": null,
"status": null,
"url": null
}
|
Present design tools, as found in the Rock Manual or Coastal Engineering Manual, for the determination of toe rock size for rubble mound breakwaters are based on test data with a large spread: data is relatively dispersed around the centre and descriptive equations have limited applicability ranges. New research has been undertaken to contribute to a more accurate description of toe rock stability. Flume tests have lead to an empirical design criterion for toe bunds in very shallow water based on the Hudson-type stability number. Herein the foreshore slope turns out to have an important influence. An approach with theoretical background has been used for toe bunds in surging wave conditions. The resulting stability description, based on local flow velocities, has been verified with existing data sets. Additional flume tests were performed to measure flow velocities at the toe bund. Results are used to calibrate the velocity-approach, providing an improved design criterion.
|
2022-09-07T11:16:25.399Z
|
1,958,435 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/IMSCCS.2008.37",
"MAG": "2535594383",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Many mobile applications such as email, calendar and web browser make use of smartphones technology. WiiKey, a proposed smart application, aims to extend the current smartphone capabilities to allow users to control the next generation Wi-Fi enabled devices found in some cars or home appliances. In this paper, Wi-Fi standards and their applications are first reviewed, and then the design and development of WiiKey prototype are described. Details of implementation of WiiKey using Java are presented. WiiKey has a potential to control smart objects in next generation of mobile devices. WiiKey brings benefits to users in their daily life and may one day become a true 'personal trust device'.
|
2022-10-03T13:30:49.977Z
|
52,294,617 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.7717/peerj.5411",
"MAG": "2890399253",
"PubMedCentral": "6140670"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://doi.org/10.7717/peerj.5411"
}
|
The estates of stately homes or manor houses are an untapped resource for assessing the ecosystem services provided by trees. Many of these estates have large collections of trees with clear value in terms of carbon storage, runoff prevention, and pollution removal along with additional benefits to biodiversity and human health. The estate of Harewood House in North Yorkshire represents an ideal example of such a stately home with a mixture of parkland and more formally planted gardens. The trees in each type of garden were analysed for height, diameter at breast height and light exposure. The data were then processed in iTrees software to generate economic benefits for each tree in both gardens. The analysis found that the larger North Front parkland garden had greater total benefits but the more densely planted formal West Garden had the greater per hectare value. In total, the trees on Harewood House estate are estimated to provide approximately £29 million in ecosystem service benefits. This study is the first to analyse the trees of stately homes for economic benefits and highlights that the trees are a valuable commodity for the estates. This should be considered in future planning and management of such estates.
|
2022-12-07T22:09:00.055Z
|
234,464,230 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.4013/PE.V16I1.19187",
"MAG": "3139043574",
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},
"license": null,
"status": null,
"url": null
}
|
Na ultima decada, a inflacao brasileira passou por periodos de forte elevacao, bem como por momentos de queda expressiva, chegando a ficar abaixo da meta, como aconteceu em 2017. Observou-se tambem periodos de juros reais bastante elevados e bastante baixos, periodos de forte controle de precos administrados e de correcao desses precos. O objetivo deste trabalho e avaliar as influencias que os precos administrados e as expectativas de inflacao tem exercido sobre as decisoes de politica monetaria, mais especificamente sobre a definicao da taxa basica de juros da economia. Com vistas a contemplar este objetivo, foi calibrada uma funcao de reacao ou regra de Taylor, nos moldes da que faz parte do modelo semiestrutural de pequeno porte utilizado pelo Banco Central e o metodo de estimacao empregado foi o de Autorregressao Vetorial com Correcao de Erro (VEC) na sua versao estrutural. Os resultados demonstram que a definicao da taxa Selic tem se baseado consideravelmente no desvio da expectativa de inflacao em relacao a meta e nos precos administrados diretamente e indiretamente pelo seu impacto nas expectativas. A influencia dessas variaveis na definicao da taxa Selic e bem maior do que a das variacoes na atividade economica.
|
2022-01-27T19:40:08.740Z
|
130,392,333 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3406/bsef.2001.16723",
"MAG": "2286002141",
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},
"license": null,
"status": null,
"url": null
}
|
Les auteurs font une revision critique des especes de Peritelini presentes en Corse avec quelques considerations sur le peuplement de cette ile. Ils decrivent trois especes nouvelles pour la science (Pseudomeira virgo, P. soror, Leptomeira nupta) et redecrivent une espece nouvelle pour la faune francaise, Pseudomeira lostiae (Desbrochers) et deux autres souvent meconnues, P. insularis (Desbrochers) et Heteromeira damryi (Tournier). Une liste des localites des specimens corses de chaque espece examines par les auteurs eux-memes, des renseignements sur la repartition et l'ecologie des taxa envisages et des dessins de details taxonomiquement interessants completent le travail.
|
2022-02-09T14:14:45.297Z
|
56,470,958 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4013/FSU.2017.182.03",
"MAG": "2766308122",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Recently, several philosophers have called attention to the idea that there are occasions on which we can perceive (at least some) mental states of others. In this paper we consider two recent proposals in this direction: the co-presence thesis (Smith, 2010) and the hybrid model (Krueger and Overgaard, 2012). We will examine the aforementioned alternatives and present some objections to both of them. Then, we will propose a way of integrating both accounts which allows us to avoid such objections. Broadly stated, our idea is that by perceiving other people’s behaviors we also perceive their mental states because behaviors co-present some features of the latter, and that this perception of others’ minds is direct and immediate because behavior is a constitutive part of the mental states in question. Keywords: mindreading, hybrid model, direct perception of other minds, co-presence thesis.
|
2022-08-20T10:42:47.279Z
|
46,951,090 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/003754978805100602",
"MAG": "2043833520",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The main purpose of this system is to develop a simulation model as well as to perform an analysis of hospital resources including sick beds, ambulances, and ambulances of Police Rescue Centers called by 119, the emergency telephone number Here, the key items we are going to analyze include the number of sick beds and ambulances, the rate of use of sick beds andambulances, time of each ambulance on duty, and delay time (from calling ambulances to the arrival at hospitals) for an emergency call. With this system, we can assist the related personnel in making a complete program ming such that all resources can be employed both efficiently and sufficiently. By using SLAM II, we can obtain the minimum number of sick beds andambulances required to sustain the indispensable requirements under the existing and abnormal conditions. At the same time, we can observe the delay time for an emergency call and the rate of use of sick beds and ambulances within the limited availability of sick beds and ambulances.
|
2022-09-06T19:04:09.740Z
|
130,175,111 |
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|
..............................................................................................................................................................
II PREFACE
................................................................................................................................................................
III TABLE
OF
CONTENTS
........................................................................................................................................
IV LIST
OF
TABLES
..................................................................................................................................................
VI LIST
OF
FIGURES
................................................................................................................................................
VII LIST
OF
ABBREVIATIONS
..............................................................................................................................
VIII ACKNOWLEDGEMENTS
....................................................................................................................................
IX DEDICATION
..........................................................................................................................................................
X INTRODUCTION
–
CONTEXT
AND
RESEARCH
OUTLINE
..........................................................................
1 INFORMALITY
..............................................................................................................................................................................
2 DEMOCRATIC
TRANSFORMATION
AND
THE
FREE
BASIC
WATER
.....................................................................................
6 SERVICE
DELIVERY
....................................................................................................................................................................
9 KHAYELITSHA
..........................................................................................................................................................................
15 SITE
C
........................................................................................................................................................................................
18 RESEARCH
FRAMEWORK
.......................................................................................................................................................
21 RESEARCH
OBJECTIVES
..........................................................................................................................................................
22 METHODOLOGY
.......................................................................................................................................................................
23 THESIS
OUTLINE
.....................................................................................................................................................................
26 LIVED
CITIZENSHIP
-‐
WATER
SERVICES,
INCLUSION
AND
NOTIONS
OF
THE
STATE
IN
SITE
C, KHAYELITSHA,
CAPE
TOWN.
.........................................................................................................................
29 INTRODUCTION
........................................................................................................................................................................
29 APPROACHES
TO
CONCEPTUALIZING
CITIZENSHIP
...........................................................................................................
31 NOTIONS
OF
AND
ENCOUNTERS
WITH
THE
STATE
IN
SITE
C,
KHAYELITSHA
..............................................................
37 DISCUSSION
..............................................................................................................................................................................
47 CONCLUSION
............................................................................................................................................................................
51 LIVED
NOTIONS
OF
THE
HUMAN
RIGHT
TO
WATER
-‐
THE
CASE
OF
SITE
C,
KHAYELITSHA
....
52 INTRODUCTION
........................................................................................................................................................................
52 THE
HUMAN
RIGHT
TO
WATER
WITHIN
THE
HUMAN
RIGHTS
FRAMEWORK
.............................................................
54 RIGHTS
TO
RESOURCES
..........................................................................................................................................................
56 LIVED
NOTIONS
OF
RIGHTS
...................................................................................................................................................
57 MATERIALITY
AND
LIVED
NOTIONS
OF
THE
RIGHT
TO
WATER
....................................................................................
60 EXPERIENCES
WITH
WATER
SERVICES
ELICITED
THROUGH
NARRATIVES
..................................................................
62 DISCUSSION
..............................................................................................................................................................................
71 IMPLICATIONS
OF
CONSIDERING
MATERIALITY
IN
LIVED
NOTIONS
OF
RIGHTS
.........................................................
75 CONCLUSIONS
..........................................................................................................................................................................
76 THESIS
CONCLUSIONS
......................................................................................................................................
78 BIBLIOGRAPHY
..................................................................................................................................................
83 APPENDICES
........................................................................................................................................................
94 APPENDIX
A:
MAPS
OF
KHAYELITSHA
AND
SITE
C
................................................................................
94 APPENDIX
B:
MAP
OF
THE
INFORMAL
SETTLEMENTS
IN
CAPE
TOWN
...........................................
97
|
2022-09-11T09:20:44.782Z
|
145,809,905 |
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|
The movement to promote improved levels of participation from groups under-represented in higher education which occurred between 1980 and 1990 neglected disabled people. The position has been addressed by the national higher education funding councils since 1992 and progress has been made. Therefore, it was surprising to find that, whilst certain social groups were highlighted, nothing was said about disabled people in the terms of reference of Sir Ron Dearing's National Committee of Inquiry. This paper describes attempts made to inform and influence the Committee. Next, it considers the Report itself. First, the recommendations for future policy which are directed specifically towards disabled people are discussed; secondly, the potential implications for disabled people of the general recommendations are explored; and thirdly, the supplementary report on students with disabilities is reviewed. The conclusion provides a brief overview of developments since the Report's publication.
|
2022-12-11T00:29:51.561Z
|
211,524,431 |
{
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|
Supplemental Digital Content is available in the text. Summary: Pollybeak deformity represents one of the most common complications of rhinoplasty that require revision rhinoplasty for correction. This article helps to understand the basis behind the deformity, which helps us to prevent and to treat this deformity. This article and video also reiterate that systematic facial analysis is important to look for imperfections and asymmetries in other parts of the face and show how a chin augmentation is performed to correct microgenia.
|
2022-12-17T17:44:23.026Z
|
158,197,508 |
{
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"DOI": "10.1163/2210-7975_hrd-9806-0027",
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|
In 2007 the global internal displacement crisis continued unabated. Although international attention to the plight of internally displaced people (IDPs) has grown significantly over the past years there was still no breakthrough in reducing the numbers and measurably improving the situation of those who had been forced to flee their homes as a result of conflict generalised violence or human rights violations. Displacement in the words of UN Secretary-General Ban Ki-moon remained "arguably the most significant humanitarian challenge that we face". Millions of people were newly displaced by conflict during 2007 chased from their homes and land by brutal government armies and militias rebel groups or hostile neighbouring communities. They joined the ranks of IDPs who had been uprooted in previous years and who remained unable to return to their homes or find other durable solutions exposed to violence and severe violations even of their most basic human rights. (excerpt)
|
2022-12-17T22:59:34.376Z
|
208,814,258 |
{
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"DOI": "10.1080/07481187.2019.1696425",
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|
Abstract For decades, public opinion polls have shown that most Americans favor physician aid in dying (PAD) but little is known about those who support PAD ballot measures. With its emphasis on self-fulfillment, personal choice, and civic and political engagement, post-materialists would argue that adopting states tend to have younger, educated, and more secular populations. County-level votes on all nine ballot measures to legalize death with dignity were subjected to multiple regression analysis. The results largely confirm the hypotheses derived from post-materialist theory, namely that education, religion, and more problematically age significant indicators of PAD ballot measure voting.
|
2022-12-20T23:26:18.440Z
|
85,582,103 |
{
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"ArXiv": null,
"DOI": "10.1111/j.1365-2486.2009.02119.x",
"MAG": "2169883246",
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},
"license": null,
"status": null,
"url": null
}
|
Peatland streams have repeatedly been shown to be highly supersaturated in both CO2 and CH4 with respect to the atmosphere, and in combination with dissolved (DOC) and particulate organic carbon (POC) represent a potentially important pathway for catchment greenhouse gas (GHG) and carbon (C) losses. The aim of this study was to create a complete C and GHG (CO2, CH4, N2O) budget for Auchencorth Moss, an ombrotrophic peatland in southern Scotland, by combining flux tower, static chamber and aquatic flux measurements from 2 consecutive years. The sink/source strength of the catchment in terms of both C and GHGs was compared to assess the relative importance of the aquatic pathway. During the study period (2007–2008) the catchment functioned as a net sink for GHGs (352 g CO2‐Eq m−2 yr−1) and C (69.5 g C m−2 yr−1). The greatest flux in both the GHG and C budget was net ecosystem exchange (NEE). Terrestrial emissions of CH4 and N2O combined returned only 4% of CO2 equivalents captured by NEE to the atmosphere, whereas evasion of GHGs from the stream surface returned 12%. DOC represented a loss of 24% of NEE C uptake, which if processed and evaded downstream, outside of the catchment, may lead to a significant underestimation of the actual catchment‐derived GHG losses. The budgets clearly show the importance of aquatic fluxes at Auchencorth Moss and highlight the need to consider both the C and GHG budgets simultaneously.
|
2022-12-26T15:56:30.544Z
|
223,062,911 |
{
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"DOI": "10.3760/CMA.J.ISSN.1673-4904.2013.10.027",
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|
Gerstmann综合征是一组表现为失写、失算、手指失认和左右辨认障碍为主的综合征.1924年由Gerstmann描述,并由此命名,国内外学者对于Gerstmann综合征的存在、病变部位、临床症状的关系和四主征之间是否有共同发病基础一直存在争议,同时四主征之间是否只是有某种联系依然未知.而且,Gerstmann综合征病因学研究仍然以脑血管病为主.现将2011年6月至2012年10月在郑州市康复医院神经内科诊断、治疗的12例Gerstmann综合征患者的临床症状、影像学特征及临床转归报道如下,以提高对该病的认识。
|
2022-01-24T19:06:06.548Z
|
122,378,094 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1086/155839",
"MAG": "2080931534",
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},
"license": null,
"status": "BRONZE",
"url": "https://doi.org/10.1086/155839"
}
|
Theoretical models for the intracluster gas in X-ray clusters of galaxies are studied. The limits of validity of all the published models are derived from self-consistent arguments and existing data. New results are presented for the well model (gas trapped in the potential well of a single galaxy) and the wind model. A scaling law is proved that allows one to apply the results calculated for spherical systems to the nonspherical groupings that are often observed. The particular line intensities that can best be used to discriminate among theoretical models or to diagnose the gas (i.e., determine abundances, temperatures, ionization states, and other properties) are listed in Tables 1-3 along with the required experimental sensitivity and resolution. Possible observing programs are described that can be carried out with existing instruments on currently operating satellites and with future space experiments (e.g., on HEAO-A, HEAO-B, and other planned X-ray missions).
|
2022-09-22T13:52:48.844Z
|
244,406,995 |
{
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"ArXiv": null,
"DOI": "10.1109/ISMSIT52890.2021.9604598",
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},
"license": null,
"status": null,
"url": null
}
|
Wireless sensor and actor networks (WSANs) compose of ordinary sensor networks and actor devices equipped with various capabilities. These networks are crucial technologies which are located at the communication layer of Internet of things. Actors (agents) are employed to provide decentralized control of the sensor networks. We propose an actor controlled framework for localization and clustering in sensor networks. To the best of our knowledge, our framework is the first which offers both localization and clustering within constant message complexity per node. In this structure, a mobile actor device traverses the sensor network to localize and cluster the sensor nodes. Total energy consumption of the sensor nodes using this method are reduced compared to the distributed approaches. Moreover, cluster quality of our algorithms is better than their counterparts. We show that our framework provides a suitable infrastructure for cluster-based applications in an energy efficient manner.
|
2022-12-16T21:03:42.954Z
|
23,681,010 |
{
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"ArXiv": null,
"DOI": "10.1073/pnas.1217838110",
"MAG": "2048153007",
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},
"license": null,
"status": "BRONZE",
"url": "https://www.pnas.org/content/pnas/110/44/17850.full.pdf"
}
|
Significance Argonaute (Ago) proteins are the key component of the RNA-induced silencing complex (RISC) and mediate RNA interference (RNAi) in association with small RNAs. Although overall the mechanism of RNAi is well understood, many molecular details of this complex process are not. The implementation of pre-steady-state kinetic techniques enabled us to develop a comprehensive minimal mechanistic model for human Ago 2 (hAgo2)-mediated target RNA binding and cleavage, dissecting binary as well as ternary complex formation and target RNA cleavage into individual substeps. The model presented provides in-depth insights into the complicated interplay of hAgo2 with small RNAs and corresponding target molecules, which in combination with available X-ray structures will eventually lead to better understanding of the underlying mechanisms of RNAi. Argonaute (Ago) proteins are the key component of the RNA-induced silencing complex and mediate RNA interference (RNAi) in association with small RNAs. Although overall the mechanism of RNAi is well understood, many molecular details of this complex process are not. Here we report about in-depth steady-state and, in particular, pre-steady-state characterization of siRNA binding, target RNA recognition, sequence-specific cleavage and product release by recombinant human Ago 2 (hAgo2). In combining our biochemical studies with crystal structures of bacterial Ago proteins and of recently released hAgo2, we relate kinetic data to conformational changes along the pathway and propose a comprehensive minimal mechanistic model describing fundamental steps during RNAi. Furthermore, in contrast to the current conception, our hAgo2 preparations are programmable with double-stranded siRNA. Accordingly, the system investigated represents a functional minimal RNA-induced silencing complex.
|
2022-12-21T15:23:24.598Z
|
109,268,968 |
{
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"DOI": "10.1061/(ASCE)0733-9445(2000)126:5(552)",
"MAG": "1982487037",
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},
"license": null,
"status": null,
"url": null
}
|
Sandwich construction provides a structural form that can be used for aviation, aerospace, marine, and mechanical/civil engineering applications. This paper introduces a truss-core sandwich panel and presents its elastic properties. Two thin flat sheets, separated by two inclined plates acting as the core and rigidly jointed at their ends, characterize the sandwich section. This construction form eliminates most of the attendant problems of conventional spot-welded or rivet-fastened sandwich panel construction. Advantages of the truss-core panel are discussed. The three-dimensional (3D) sandwich panel is idealized as an equivalent 2D orthotropic thick plate continuum. Equivalent bending, twisting, and transverse shear stiffness are derived, and the influence of the relatively weak shear stiffness on the behavior is discussed. By integrating these elastic stiffness constants into closed-form solution, panel response is calculated. The calculated results, which require significantly less computational effort, agree well with 3D finite-element analysis. Comparisons of stiffnesses and deflections with the corresponding responses of conventional sandwich construction are provided. This study indicates that the truss-core sandwich panel performs better because of its inherently higher flexural resistance per unit weight.
|
2022-12-28T19:53:41.219Z
|
246,452,883 |
{
"externalids": {
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"DOI": "10.36568/gelinkes.v20i1.18",
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},
"license": "CCBYSA",
"status": "GOLD",
"url": "https://gelinkes.poltekkesdepkes-sby.ac.id/index.php/gelinkes/article/download/18/8"
}
|
The brick industry is an industry where almost all of the processes are done traditionally. Workers' body postures when working are often not ergonomic, so there is a risk of causing muskuloskeletal complaints. This study aims to determine the effect of work posture on musculoskeletal complaints in brick industry workers in Kasreman Village, Kandangan District, Kediri Regency.
This type of research is analytic observational with a cross-sectional approach. This study includes a population study with the entire population as a sample of 57 people. Data were collected by observing work postures using the Ovako Working Analysis System (OWAS) method and interviews about musculoskeletal complaints felt by workers using the Nordic Body Map (NBM) questionnaire. The data were analyzed univariately and bivariately with Chi Square test and continued with Fisher's Exact.
The results of this study indicate that most of the workers have a high category of work posture, aged > 35 years, and have high category of musculoskeletal complaints. Statistical test results show that there is an effect of work posture and age on musculoskeletal complaints in brick industry workers in Kasreman Village, Kandangan District, Kediri Regency in 2021.
It is recommended for workers to pay attention to their work postures, adjust work and rest times, and stretch muscles. Industrial owners should pay more attention to workplace conditions, arrange work and rest times, and be able to provide sufficient and shady land to rest.
|
2022-02-04T01:57:19.236Z
|
63,479,326 |
{
"externalids": {
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"DOI": "10.1093/ACPROF:OSO/9780195054927.003.0011",
"MAG": "2484118417",
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|
This chapter presents a synthesis of the discussions in the preceding chapters. The main conclusion is that the left cerebral hemisphere, in comparison with the right, is specialized for motor selection of both the oral and manual musculature. This is particularly true of movements specifiable within intrapersonal space, and it holds whether the movements to be programmed are components of a communication system or not. A consequent theme throughout is that human communication has been influenced by the characteristics of the motor programming systems that control the relevant oral and manual musculature. Lateralization of function in the brain, manual apraxia, visuoconstructional disorders, disorders in manual sign language, and sex differences in functional brain organization are discussed.
|
2022-02-11T13:51:34.878Z
|
209,450,997 |
{
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"ArXiv": null,
"DOI": "10.22038/IJP.2019.44136.3660",
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"license": null,
"status": null,
"url": null
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|
Background: Statistics have shown that the rate of technical failure in peritoneal dialysis (PD) is greater than hemodialysis. In this regard, the present study is aimed to determine the prevalence and risks factors of technique failure of PD in Iranian children using the country’s computerized PD data registry system. Materials and Methods: Data of 405 PD patients younger than 20 years old were extracted from Iranian PD registry. The joint models of longitudinal and time-to-event data were used to assess independent risk factors of PD technique failure. Results: PD technique failure occurred in 17.3% of the patients. 1 ng/ml increase in the baseline level of ferritin and 1 mmHg increase in the baseline systolic blood pressure will result in 0.11% (Hazard Ratio [HR]=1.0011; p=0.001), and 1.25% (HR=1.0125; p=0.046) increase in the risk of PD technique failure, respectively. In addition, 1 g/dl decrease in the baseline hemoglobin will cause a 16.25% increase in the risk of PD technique failure (HR=0.8602; p=0.026). Finally, 1 mg/l decrease in the blood urea nitrogen over time after starting PD will result in 1.75% increase in the risk of PD technique failure (HR=0.9829; p=0.006). Conclusion: The findings from this study showed that an increase in ferritin as well as systolic blood pressure at the beginning of PD increase the risk of technique failure. Furthermore, an increase in the hemoglobin level at the beginning of PD as well as an increase in the blood urea nitrogen over time after starting PD have protective impacts on pediatric PD technique failure.
|
2022-09-08T22:23:40.462Z
|
237,946,597 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1136/bmjopen-2020-046200",
"MAG": null,
"PubMedCentral": "8477330"
},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://bmjopen.bmj.com/content/bmjopen/11/9/e046200.full.pdf"
}
|
Objectives To compare global warming potential (GWP) of hospitals converting from single-use sharps containers to reusable sharps containers (SSC, RSC). Does conversion to RSC result in GWP reduction? Design Using BS PAS 2050:2011 principles, a retrospective, before/after intervention quantitative model together with a purpose-designed, attributional ‘cradle-to-grave’ life-cycle tool, were used to determine the annual greenhouse gas (GHG) emissions of the two sharps containment systems. Functional unit was total fill line litres (FLL) of sharps containers needed to dispose of sharps for 1-year period in 40 trusts. Scopes 1, 2 and 3 emissions were included. Results were workload-normalised using National Health Service (NHS) national hospital patient-workload indicators. A sensitivity analysis examined areas of data variability. Setting Acute care hospital trusts in UK. Participants 40 NHS hospital Trusts using RSC. Intervention Conversion from SSC to RSC. SSC and RSC usage details in 17 base line trusts immediately prior to 2018 were applied to the RSC usage details of the 40 trusts using RSC in 2019. Primary outcome measure The comparison of GWP calculated in carbon dioxide equivalents (CO2e) generated in the manufacture, transport, service and disposal of 12 months, hospital-wide usage of both containment systems in the 40 trusts. Results The 40 trusts converting to RSC reduced their combined annual GWP by 3267.4 tonnes CO2e (−83.9%); eliminated incineration of 900.8 tonnes of plastic; eliminated disposal/recycling of 132.5 tonnes of cardboard and reduced container exchanges by 61.1%. GHG as kg CO2e/1000 FLL were 313.0 and 50.7 for SSC and RSC systems, respectively. A sensitivity analysis showed substantial GHG reductions within unit processes could be achieved, however, their impact on relevant final GWP comparison varied <5% from base comparison. Conclusions Adopting RSC is an example of a sustainable purchasing decision that can assist trusts meet NHS GHG reduction targets and can reduce GWP permanently with minimal staff behavioural change.
|
2022-12-19T03:47:52.348Z
|
236,561,025 |
{
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"DOI": "10.3126/JPAHS.V8I1.36856",
"MAG": "3161664898",
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"license": null,
"status": null,
"url": null
}
|
Introduction: The Coronavirus Disease 2019 (COVID-19 ) pandemic has led to infection and deaths worldwide. The clinical and laboratory findings at presentation to emergency can provide clue for deaths. This study aims to analyze COVID-19 deaths, and clinical-laboratory findings at presentation.
Method: This is a retrospective cross-sectional study conducted at Patan Hospital, Patan Academy of Health Science, Lalitpur, Nepal to analyze mortality due to COVID-19 during the year 2020. The study describes the clinical presentation, laboratory parameters at the time of presentation to the emergency department and clinical course during hospital stay.
Result: Among 133 COVID-19 deaths analyzed, the median age was 61y (2d to 91y), males 73(54.9%), hypertension in 34(25.6%), 104(78.1%) had shortness of breath, 70(52.6%) fever and 34(25.6%) had cough on presentation. Median oxygen saturation on arrival was 77%, all 133(100%) required oxygen. Oxygen requirement at admission, ferritin (median 603 mcg/L), C- Reactive protein (median CRP 89.5 mg/) and lactate dehydrogenase (median LDH, 432 u/L) were not significantly correlated with duration of disease or hospital/ICU stay. Median duration of disease was 10d, hospital stay 8d and ICU stay 3d. COVID-19 deaths occurred due to respiratory failure in 105(78.9%).
Conclusion: COVID-19 deaths were due to respiratory failure in 2/3rd (78.9% of 133), more in middle age (>46y) males with comorbidities, commonly hypertension. Abnormal vital signs, elevated CRP, ferritin, LDH, were seen in COVID-19 deaths. Oxygen requirement at admission was not correlated with duration of disease, or hospital/ICU stay.
|
2022-01-27T20:16:00.812Z
|
150,893,241 |
{
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"DOI": "10.1080/00344890208523200",
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}
|
International Institute for Democracy and Electoral Assistance, United Nations and International Foundation for Election Systems Stockholm, Sweden: International IDEA, October 1998.. CD‐ROM, www.aceproject.org (for Internet version).
|
2022-02-09T03:38:45.491Z
|
32,669,736 |
{
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"DOI": "10.1142/S0129054116500040",
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},
"license": null,
"status": null,
"url": null
}
|
The frequency-hopping sequence set with low-hit-zone (LHZ FHS set) is useful for eliminating multiple-access interference in quasi-synchronous frequency-hopping multiple access systems. In this paper, basing on Cyclotomy, the discrete logarithm function and the Chinese remainder theorem, we construct two classes of LHZ FHS sets which have new parameters not covered in the literature. It is proved that proposed LHZ FHS sets are optimal respectively with respect to the Peng-Fan-Lee bounds.
|
2022-07-15T09:10:31.650Z
|
19,290,432 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1109/DEMPED.2009.5292800",
"MAG": "1994145285",
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},
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|
Demodulation techniques extract modulating currents induced by induction motors rotor faults and directly evaluate these fault currents in time and frequency domain. Vector representation of amplitude and phase modulation is analyzed with the investigation, how both modulations change with changing parameters. It is proved that fault indicators of amplitude modulation do not change with motor changing parameters and they are the base of rotor faults detection. Two demodulation methods based on complex analytical signal are presented. Experiments were focused to IM energized from line and inverters.
|
2022-09-10T18:33:11.767Z
|
31,283,338 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1159/000075377",
"MAG": "2018310350",
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},
"license": null,
"status": null,
"url": null
}
|
The aim of this prospective study was to determine whether preterm infants with bronchopulmonary dysplasia (BPD) and signs of increased pulmonary artery pressure have a deficiency of plasma arginine (ARG) and systemic nitric oxide (NO) synthesis. Plasma amino acid concentrations, Doppler pulmonary systolic time intervals (ratio of acceleration time and ejection time corrected for heart rate: AT/ETC) and urinary nitrate and nitrite concentrations were determined at the 28th day postnatal age and at 36 weeks postmenstrual age in 73 preterm infants less than 30 weeks gestational age. The AT/ETC ratios were significantly lower in infants with BPD (n = 32) compared to controls. However, total amino acid concentrations, ARG intake as well as plasma ARG concentrations were not different between groups (median (interquartile-range) µmol/l): control: 58 (42.5–75.5) and 54.5 (42–71) at day 28 and 36 weeks; BPD: 54.5 (31.5–70.5) and 43 (35–62), respectively. Urinary nitrate and nitrite concentrations, were not different between groups at day 28, but significantly higher in infants with BPD at 36 weeks (p = 0.014). In conclusion, plasma ARG concentrations and systemic NO synthesis were not deficient in preterm infants with BPD and signs of elevated pulmonary artery pressure.
|
2022-09-14T11:26:51.602Z
|
42,034,187 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/26.2785",
"MAG": "2167747598",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The joint statistical analysis of duration D and intensity R of rain exceedances relevant to the design of microwave communication systems is considered. The data analyzed are derived from point precipitation-rate observations recorded over a period of 49 years in the city of Barcelona, Spain, using a Jardi gauge. The concept of event and the duration of a single exceedance of a threshold R within that event is introduced. The analysis shows the parametric R dependence of the annual average number of exceedances and of the average duration. >
|
2022-09-15T08:23:38.381Z
|
253,239,296 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1145/3556055.3556064",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The issue of rural land transfer has always been a hotspot and a difficult issue, due to historical reasons, as well as the level of regional economic development and social infrastructure construction, there are still some deficiencies in the solutions. The land management information system built by using advanced network information technology can provide more accurate and detailed information for relevant organizations and effectively promote the solution of problems. This paper therefore explores the construction of a network platform for rural land management information. The author uses a database management framework structured language in the system design process, sets up several modules in the platform functions and simulates the final implementation of the system.
|
2022-11-05T17:26:33.402Z
|
39,891,464 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4236/CS.2016.713342",
"MAG": "2554504874",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In Mobile Ad-Hoc Networks (MANET), the group communication for multiple senders and receivers threatens the security features. The multicasting is provoked to various security attacks, eavesdropping etc., hence secure multicasting requires imperative significance. The secure multicast tree construction using Bacterial Foraging Optimization (BPO) algorithm is proposed to develop a secure multicast tree construction in MANET. During routing, the proposed algorithm utilizes the public routing proxy to hide identity of the sender and receiver from other nodes for maintaining confidentiality. The public routing proxy is estimated using bacterial foraging optimization algorithm and path reliability is evaluated after the each iteration. Path reliability enhances the security of the network from black hole attacker and DoS attackers compared to traditional approaches for secure multicast tree formation in MANETs. By simulation results, we have shown that the proposed technique offers authentication and confidentiality during secure multicasting which is compared to conventional multicast tree formation algorithms in MANETs.
|
2022-12-08T16:02:19.756Z
|
238,852,517 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/humrep/deab125.033",
"MAG": "3193813627",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
How do fertility clinics’ websites of the UK, Belgium and Spain present the medical risks of egg donation and incentives?
Spanish and UK websites typically included more incentives to recruit egg donors compared to the Belgian websites. OHSS was overall the most discussed risk.
People commonly turn to the internet for initial information. Primary presentations of information of a subject co-determine how an individual interprets the topic and thus influence later decisions. Considering the growing demand and clinics’ dependency on egg donors, some scholars have expressed concerns that clinics might (initially) misrepresent risks to recruit more egg donors. Offering appealing incentives may also encourage potential donors to dismiss possible risks and side-effects.
Therefore, it is important to see how incentives (both monetary and non-monetary rewards) and risks are presented on the websites of fertility clinics, the first source of information for egg donors.
This study is part of the EDNA-project, a multi-phased comparative study (2017-2021), that aims to explore the social, political, economic and moral configuration of egg donation in the United Kingdom, Belgium and Spain. In this study, we only focused on the medical risks of egg donation and incentives presented on the fertility clinics’ websites of the three countries.
We analysed the websites of all Belgian fertility clinics (n = 18), and a maximum variation sample in the UK (n = 21) and Spain (n = 23). The sampling was based on the geographical location of the clinic, size/number of cycles performed each year, the clinic’s status (independent or part of a larger clinical group) and whether the clinic was public or privately funded in the UK. Frame analysis and content analysis were used for analysis in Nvivo12.
No misrepresentation of risks was found. There was an extensive variety in the representation of risks. There were differences between the websites of the three countries (e.g. the risks of having acne was only discussed on Spanish websites), but also remarkable differences within the websites of a particular country (of the 40 risks, 13 were one-off mentions, each found on a single website). A description of a risk was generally accompanied by a minimization or normalization of the risk, or a statement about the fertility clinic’s excellent care for their egg donors. These three approaches were often combined.
Our analysis differentiated between incentives (i.e. external rewards) and emotional appeals. An appeal to emotions (e.g. empathy) can also motivate behavioural action (e.g. donation) but was not considered as an incentive since there is no external reward.
While Belgian websites used almost no incentives, Spanish and UK websites used gratitude and a rewarding experience as incentives. However, only Spanish websites used free medical tests as incentives, while UK websites were the only ones that used discounts received with egg sharing as an incentive. All countries’ websites used emotional appeals by enticing feelings of empathy for the recipients.
Not all UK and Spanish fertility clinics’ websites were analysed. However, our international team of researchers applied a maximum variation sampling strategy. This generated samples of clinics per country that were as diversified as possible.
The study shows that incentives are more often used on the UK and Spanish websites than on the Belgian websites. All three countries’ websites used emotional appeals. It should be studied how effective these incentives and emotional appeals are, and if there is a correlation with the potential donors’ risk-perceptions.
not applicable
|
2022-12-10T09:58:25.447Z
|
84,776,993 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/NP50056A025",
"MAG": "2033181507",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Isolement de medicarpine, de sativane, de leurs analogues methoxy et de plusieurs composes non identifies. Tests biologiques sur laitue et luzerne en relation avec l'etude de l'autotoxicite de la luzerne
|
2022-12-19T04:05:35.556Z
|
14,214,047 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/WSC.1994.717167",
"MAG": "1979093414",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We present and compare two ways of applying the regenerative method of simulation output analysis to simulate the steady-state behavior of irreducible discrete time Markov chains having a finite state space. The "standard" approach involves defining the regenerative cycles based on the times a particular "return" state is visited. The alternative approach involves using "splitting" to define the regenerative cycles. We present a way of selecting the splitting distribution that guarantees that the splitting cycles are shorter than the standard cycles, and that the variance estimates produced by the splitting approach are less variable than the variance estimates produced by the standard approach.
|
2022-12-20T04:17:02.361Z
|
229,372,379 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/0161734620976408",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
It is of vital importance to identify the pleural line when performing lung ultrasound, as the pleural line not only indicates the interface between the chest wall and lung, but offers additional diagnostic information. In the current clinical practice, the pleural line is visually detected and evaluated by clinicians, which requires experiences and skills with challenges for the novice. In this study, we developed a computer-aided technique for automated pleural line detection using ultrasound. The method first utilized the Radon transform to detect line objects in the ultrasound images. The relation of the body mass index and chest wall thickness was then applied to estimate the range of the pleural thickness, based on which the pleural line was detected together with the consideration of the ultrasonic properties of the pleural line. The proposed method was validated by testing 83 ultrasound data sets collected from 21 pneumothorax patients. The pleural lines were successfully identified in 76 data sets by the automated method (successful detection rate 91.6%). In those successful cases, the depths of the pleural lines measured by the automated method agreed with those manually measured as confirmed with the Bland-Altman test. The measurement errors were below 5% in terms of the pleural line depth. As a conclusion, the proposed method could detect the pleural line in an automated manner in the defined data set. In addition, the method may potentially act as an alternative to visual inspection after further tests on more diverse data sets are performed in future studies.
|
2022-12-21T00:47:30.927Z
|
219,329,433 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2987/19-6863.1",
"MAG": "3033050336",
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://meridian.allenpress.com/jamca/article-pdf/36/1/16/2525727/19-6863_1.pdf"
}
|
Commercial aerosolized insecticides can be implemented as a community-based approach to targeted indoor residual spraying against Aedes aegypti, but their efficacy on pyrethroid-resistant mosquitoes has not yet been evaluated. Two commercial aerosolized products (H24 Poder Fulminante Ultra Eficaz®, carbamate, and Baygon Ultra Verde®, pyrethroid) were sprayed on common indoor surfaces e.g., cement, plywood, and cloth, and tested for their residual efficacy on susceptible and field-derived pyrethroid-resistant Ae. aegypti strains using the WHO cone bioassays. Overall, ≥80% 24-h mortality was observed for both products for at least 4 wk regardless of the mosquito strain or surface type used. H24 Poder Fulminante Ultra Eficaz showed the highest residual potency, sustaining >80% mortality for 7-wk posttreatment regardless of mosquito strain and surface type. For Baygon Ultra Verde, the mean mortality of female Ae. aegypti remained >80% for a shorter period (4-6 wk). Nonpyrethroid commercial aerosolized formulations can provide a lasting residual effect indoors compatible with the need for rapid and lasting mosquito control during outbreaks and may be suitable for community-based targeted indoor residual spraying.
|
2022-06-26T00:13:34.767Z
|
23,898,698 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1600-0625.1995.tb00209.x",
"MAG": "1978734646",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract Prostaglandins have been shown to be involved in the suppression of contact hypersensitivity (CHS) by so‐far ill understood mechanisms. T‐cell migration across the lining of cytokine‐activated endo‐thelial cells (EC) is thought to be a central step in the initiation of CHS. The aim of our investigation was therefore to examine whether prosta‐glandin E1 (PGE1) influences cytokine‐induced TK‐1 mouse T‐cell lymphoma adhesion to eEnd.2 mouse endothelioma cells. Here, we report that PGE1 (10−12− 10−8 M) dose‐dependently reduced TNFα‐induccd T‐cell binding, while TNFα‐unstimulated adhesion was not affected. To test whether PGE, acted primarily on T‐cells or on EC, they were separately pretreated with PGE, prior to the adhesion assay. Selective PGE1 pretreatment of eEnd.2, but not of TK‐1 dose‐dependenlly inhibited TNFα, stimulated T‐cell adhesion. Since binding of TK‐1 to TNFα‐treated eEnd.2 is mediated by the interaction of ICAM‐1 and VCAM‐1 (on EC) with their receptors LFA‐1 and VLA‐4 (on T‐cells), we further investigated whether PGE1 would modulate the expression of these molecules. FACS‐analysis revealed PGE1 to inhibit TNFα‐induced upregulation of ICAM‐1, but not of VCAM‐I on EC. Furthermore, constitutive LFA‐1 and VLA‐4 expression on T‐cells was not affected by PGE1. We conclude that PGE1 supresses T‐cell adhesion to EC by selectively inhibiting TNFα‐induced upregulation of ICAM‐1 on EC. This may be one mechanism by which prostaglandins suppress immune responses requiring T‐cell EC interactions such as contact hypersensitivity in skin.
|
2022-09-06T21:04:14.116Z
|
152,966,699 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5860/choice.33-6452",
"MAG": "612728486",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
"The Cultural Patronage of Medieval Women" is the first volume exclusively devoted to an examination of the significant role played by women as patrons in the evolution of medieval culture. The twelve essays in this volume look at women not simply as patrons of letters but also as patrons of the visual and decorative arts, of architecture, and of religious and educational foundations.Patronage as a means of empowerment for women is an issue that underlies many of the essays. Among the other topics discussed are the various forms patronage took, the obstacles to women's patronage, and the purposes behind patronage. Some women sought to further political and dynastic agendas; others were more concerned with religion and education; still others sought to provide positive role models for women. The amusement of their courts was also a consideration for female patrons.These essays also demonstrate that as patrons women were often innovators. They encouraged vernacular literature as well as the translation of historical works and of the Bible, frequently with commentary, into the vernacular. They led the way in sponsoring a variety of genres and encouraged some of the best-known and most influential writers of the Middle Ages. Moreover, they were at the forefront in fostering the new art of printing, which made books accessible to a larger number of people. Finally, the essays make clear that behind much patronage lay a concern for the betterment of women.
|
2022-10-27T17:53:33.286Z
|
2,214,870 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3389/fmicb.2017.01348",
"MAG": "2738928056",
"PubMedCentral": "5526965"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.frontiersin.org/articles/10.3389/fmicb.2017.01348/pdf"
}
|
The prominent feature of rhizobia is their molecular dialogue with plant hosts. Such interaction is enabled by the presence of a series of symbiotic genes encoding for the synthesis and export of signals triggering organogenetic and physiological responses in the plant. The genome of the Rhizobium sullae type strain IS123T nodulating the legume Hedysarum coronarium, was sequenced and resulted in 317 scaffolds for a total assembled size of 7,889,576 bp. Its features were compared with those of genomes from rhizobia representing an increasing gradient of taxonomical distance, from a conspecific isolate (Rhizobium sullae WSM1592), to two congeneric cases (Rhizobium leguminosarum bv. viciae and Rhizobium etli) and up to different genera within the legume-nodulating taxa. The host plant is of agricultural importance, but, unlike the majority of other domesticated plant species, it is able to survive quite well in the wild. Data showed that that the type strain of R. sullae, isolated from a wild host specimen, is endowed with a richer array of symbiotic genes in comparison to other strains, species or genera of rhizobia that were rescued from domesticated plant ecotypes. The analysis revealed that the bacterium by itself is incapable of surviving in the extreme conditions that its host plant can tolerate. When exposed to drought or alkaline condition, the bacterium depends on its host to survive. Data are consistent with the view of the plant phenotype as the primary factor enabling symbiotic nitrogen fixing bacteria to survive in otherwise limiting environments.
|
2022-12-10T09:13:27.015Z
|
20,762,748 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/10556780500159128",
"MAG": "1995978630",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
In this paper, we study some well-known cases of nonlinear programming problems, presenting them as instances of inexact or semi-infinite linear programming. The class of problems considered contains, in particular, semi-definite programming, second-order cone programming and special cases of inexact semi-definite programming. Strong duality results for the nonlinear problems studied are obtained via the Lagrangian duality. Using these results, we propose some dual algorithms for the studied classes of problems. The proposed algorithms can be interpreted as cutting plane or discretization algorithms. Finally, some comments on the convergence of the proposed algorithms and on preliminary numerical tests are given.
|
2022-12-16T02:10:18.513Z
|
234,384,804 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.17966/JMI.2020.25.4.65",
"MAG": "3123893636",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Onychomycosis is a fungal infection of the nail unit. Compared to other superficial dermatophytoses of the skin and hair, onychomycosis is associated with a chronic course and frequent recurrence. Originally, structural characteristics of the nail, such as poor vascular supply and thick layers of hard keratin, were thought to be limiting
factors for efficient drug delivery, resulting in prolonged treatment. However, recent research reveals the following crucial mechanisms contributing to the chronicity of nail dermatophytosis: innate characteristics of Trichophyton rubrum, formation of dormant spores called arthroconidia, physical and immunologic characteristics of the nail
apparatus, and alteration of the defense system of the host. T. rubrum, the most common causative fungal pathogen for onychomycosis, acquires selective immune tolerance toward the host's defense system. Transformation into dormant phases, such as arthroconidia, creates greater resistance to antifungal medication and nonnutritive
environments. The anatomical and biological structures of the nail allow immune evasion, increase infection susceptibility, and promote biofilm formation. Key regulators of the host's innate and adaptive immune systems are downregulated as infection persists, and age-associated immunomodulation aggravates the process.
|
2022-01-27T01:42:36.526Z
|
23,205,910 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3978/j.issn.2305-5839.2015.04.04",
"MAG": "416463488",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Many studies have examined the association between the CYP1A2 rs2069514 polymorphism gene polymorphisms and lung cancer risk in various populations, but their results have been inconsistent. The PubMed was searched for case-control studies published up to Sep 01, 2014. Data were extracted and pooled odds ratios (ORs) with 95% confidence intervals (CI) were calculated. In this meta-analysis, we assessed six published studies involving comprising 1,168 cases and 1,598 controls of the association between CYP1A2 rs2069514 polymorphism and lung cancer risk. For the homozygote A/A and A allele carriers (G/A + A/A), the pooled ORs were 1.47 (95% CI, 1.15-1.99; P=0.007 for heterogeneity) and 1.43 (95% CI, 1.07-1.90; P=0.000 for heterogeneity), when compared with the homozygous wild-type genotype (G/G). In the stratified analysis by ethnicity, the significantly risks were found among non-Asians for both the A allele carriers and homozygote A/A. However, no significant associations were found in Asian population all genetic models. These results from the meta-analysis suggest that CYP1A2 rs2069514 polymorphism contributes to risk of lung cancer among non-Asian population.
|
2022-02-12T19:27:14.700Z
|
165,257,299 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.22630/AAS.2018.57.2.17",
"MAG": "2889999782",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
<jats:p />
|
2022-10-21T00:09:05.555Z
|
235,172,619 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/14772019.2021.1917705",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Rove beetles of the Staphylinine group of subfamilies represent the most species-rich clade of Staphylinidae, which in turn is the most speciose beetle family. While several relationships within the Staphylinine group are well supported by morphological and molecular data alike, the basal relationships within the clade remain unresolved. In particular, understanding the largest radiation on the beetle tree of life is complicated by the absence of early-diverging transitional fossils. Here we describe a new genus and species of the Staphylinine group of subfamilies from the Lower Cretaceous Yixian Formation in eastern China (c. 125 Ma). Paroxyporus fossilis Cai gen. et sp. nov. shares a number of characters with the monogeneric subfamily Oxyporinae, namely its prognathous head with prominent apically curved mandibles, contiguous procoxae, moderately separated mesocoxae and abdominal intersegmental membranes with a ‘brick-wall’ pattern. It, however, shares oval procoxae and ‘U’-shaped abdominal impressions with the monogeneric subfamily Megalopsidiinae. A parsimony analysis of 211 morphological characters recovered Paroxyporus gen. nov. as sister to the whole Staphylinine group except Oxyporinae, linking Oxyporinae and other clades of the Staphylinine group, and it seems to be a stem member of the Staphylinine group. As such, Paroxyporus gen. nov. may represent an early-diverging isolated lineage within the Staphylinine group, a lineage that has been recognized on the basis of morphological data but challenged by some recent molecular studies, or alternatively a stem member of the Staphylinine group. Together with described fossil members of the subfamily Oxyporinae, Paederine and Staphylinine from the Yixian Formation, Paroxyporus fossilis gen. et sp. nov. is one of the earliest representatives of the Staphylinine group in the fossil record, providing an important calibration point for understanding the timing of the early diversification of rove beetles in the Mesozoic. http://zoobank.org/urn:lsid:zoobank.org:pub:40F8F256-7E9F-478E-AC96-1EB1BCE5A02B
|
2022-10-24T15:43:53.415Z
|
245,445,700 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1037/pst0000415",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Most research to date with Interpersonal Reconstructive Therapy (IRT: Benjamin, 2006) involves application with patients who qualify for the acronym "CORDS": Comorbid, Often Rehospitalized, Dysfunctional, and Suicidal. A case formulation (CF) based on interpersonal copy process theory defines links between presenting symptoms and patterns of affect, cognition, and behavior that invoke safety or threat and were learned and internalized in close relationships. The "gift of love" (GOL) hypothesis is that the wish to receive love and acceptance from specific internalized attachment figures organizes and propels problem patterns and their associated symptoms. Through a series of steps, IRT seeks to help patients become aware of and learn about their copied patterns, including where they were learned, the role they play in maintaining connection with internalized attachment figures, and their functions in the present. The goal is to help a patient differentiate from their "family in the head" and pursue healthy behaviors and self-concepts. With awareness and differentiation comes the possibility of letting go of problematic quests for love and acceptance from the internalized attachments and to choose healthy alternatives instead. As an integrative method, safety planning in IRT shares much with other approaches. What is unique is how therapists utilize the CF to guard against unsafe behavior as an ongoing part of the treatment process with patients with suicidality. This article provides an overview and illustration emphasizing these unique aspects of the IRT approach to safety planning in the context of individual psychotherapy with adults. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
|
2022-12-13T20:46:36.604Z
|
60,900,547 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/VETEC.1992.245452",
"MAG": "1587367539",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The performance of pi /4-QDPSK system is presented in a fast Rayleigh fading/slow lognormal shadowing/delay spread/AWGN channel in the presence of cochannel interference. The performance of the system is measured in terms of symbol error rate (SER). The system was simulated using two-ray model for normalized value of Doppler shift (0.001), degree of shadowing ( sigma =6), and several values of time delays and carrier-to-interference ratios. It is seen that the system performance is limited by the presence of cochannel interference. When cochannel interference is negligible, the system performance is dominated by the ratio between the main path signal and the delayed path signal, and the differential time delay between them. It is observed that the shadowing degrades the system performance at low CNR but not at high CNR (i.e., CNR>50 dB). The irreducible symbol error rate (ISER) does not vary significantly as the differential time delay between the two path varies.<<ETX>>
|
2022-12-15T01:18:38.909Z
|
31,782,200 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/00042560-199712150-00012",
"MAG": "2322452215",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://journals.lww.com/jaids/Fulltext/1997/12150/Induction_of_Chronic_Inflammatory_Arthropathy_and.12.aspx"
}
|
To compare the pathogenicity of HTLV-I derived from patients with HTLV-I-associated myelopathy (HAM)/tropical spastic paraparesis (TSP) and that from patients with adult T-cell leukemia (ATL), neonatal WKA rats were inoculated with either an HTLV-I-infected T-cell line (Fuk line) newly established from a HAM/TSP patient or MT-2 derived from a patient with ATL. Of 38 rats, 34 developed mesenchymal tumors (89%) only after 14 months of age, irrespective of the cell lines used. The rats inoculated with the Fuk line developed severe arthritis (27%) and anti-type II collagen antibody (64%), and less frequently, paraparesis (7%). Those inoculated with MT-2 developed paraparesis (23%), but not arthritis. Cyclophosphamide (CY) administration to induce immunosuppression in the Fuk line-inoculated rats increased the frequency of paraparesis (70%), but decreased the frequency of tumors (20%). HTLV-I proviral DNA was found in the spinal cord, sciatic nerves, tumors, and joints, whereas pX mRNA was detected in the sciatic nerves and tumors, but not in the spinal cord and joints. As a result, HTLV-I is considered to facilitate development of both chronic inflammatory arthropathy associated with autoimmunity and mesenchymal tumors in rats by experimental infection, and its pathogenicity is likely to be greatly influenced by the host immune state.
|
2022-12-16T02:59:02.030Z
|