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stringlengths 57
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the decreased activity of rna synthesis in senescent cell nuclei was demonstrated from both the transcriptional assay and the estimation of the processing activity , i.e. , polyadenylation of the transcripts .
|
process_includes_biological_process
|
{
"id": "C1328948",
"name": "rna synthesis",
"pos": [
26,
39
]
}
|
{
"id": "C0949765",
"name": "polyadenylation",
"pos": [
173,
188
]
}
|
the decreased activity of rna synthesis in senescent cell nuclei was demonstrated from both the transcriptional assay and the estimation of the processing activity , i.e. , polyadenylation of the transcripts .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcriptional",
"pos": [
96,
111
]
}
|
{
"id": "C0949765",
"name": "polyadenylation",
"pos": [
173,
188
]
}
|
in particular , the capacity of the k-unique antigen to induce radioresistant immunity in c3hf mice appears to be lost on long term cultured tumour cells even though the tumour remains susceptible to in vivo immune responses directed against the k-unique antigen .
|
process_includes_biological_process
|
{
"id": "C0020964",
"name": "immunity",
"pos": [
78,
86
]
}
|
{
"id": "C0301872",
"name": "immune",
"pos": [
208,
214
]
}
|
although tumor promoters are generally believed to alter gene expression , we have found a specific gene whose transcription is modified by treatment with tpa .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene expression",
"pos": [
57,
72
]
}
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
111,
124
]
}
|
this dna sequence contains a transcription promoter , a region coding for a 32-amino-acid polypeptide containing multiple isoleucine , valine , and leucine codons , and a transcription termination site preceding the first structural gene .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
29,
42
]
}
|
{
"id": "C0597600",
"name": "transcription termination",
"pos": [
171,
196
]
}
|
on the basis of the different test systems for investigation of immunecompetence and tumourspecific immunity it was possible to demonstrate that patients with melanoma , especially of clinical stages ii and iii , have a weak , sometimes an anergic immune reaction against their own tumour .
|
process_includes_biological_process
|
{
"id": "C0020964",
"name": "immunity",
"pos": [
100,
108
]
}
|
{
"id": "C0206120",
"name": "anergic",
"pos": [
240,
247
]
}
|
this appears to be explained by mitotic division shortly after birth without cell division , i.e. , karyokinesis without cytokinesis .
|
process_includes_biological_process
|
{
"id": "C0007590",
"name": "cell",
"pos": [
77,
81
]
}
|
{
"id": "C0010813",
"name": "cytokinesis",
"pos": [
121,
132
]
}
|
comparative study of the implantation growth of nephrogenic tissue in a 17-day-old embryo of rats and the epithelium of nephrons in the one-month-old animals showed that nephrogenic tissue in the implants manifested regularities characteristic of its histogenesis .
|
process_includes_biological_process
|
{
"id": "C1621966",
"name": "growth",
"pos": [
38,
44
]
}
|
{
"id": "C0178679",
"name": "histogenesis",
"pos": [
251,
263
]
}
|
the more specific behavior form of hunger -- feeding motivation -- involves structures that include the motor and parietal cortex , amygdala , and medial hypothalamus ;
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behavior",
"pos": [
18,
26
]
}
|
{
"id": "C0026605",
"name": "motivation",
"pos": [
53,
63
]
}
|
the nature of the relationship between those psychological processes which influence waking behavior and cognition , and those which influence the content of nocturnal dreams , is a question both interesting and unresolved .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behavior",
"pos": [
92,
100
]
}
|
{
"id": "C0009240",
"name": "cognition",
"pos": [
105,
114
]
}
|
the nature of the relationship between those psychological processes which influence waking behavior and cognition , and those which influence the content of nocturnal dreams , is a question both interesting and unresolved .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behavior",
"pos": [
92,
100
]
}
|
{
"id": "C0013117",
"name": "dreams",
"pos": [
168,
174
]
}
|
in spontaneously breathing or paralyzed , ventilated , decerebrate cats . bilateral pneumotaxic center lesions and bilateral vagotomy resulted in apneusis characterized by a marked prolongation of inspiratory duration ( ti ) and , concomitantly , an elevation of tidal volume ( vt ) and reduction of respiratory frequency ( f ) .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "breathing",
"pos": [
17,
26
]
}
|
{
"id": "C0004048",
"name": "inspiratory",
"pos": [
197,
208
]
}
|
the parathyroid glands on the second postoperative day show cellular hypertrophy and on the third and fourth days signs of rapid cell proliferation with numerous mitoses .
|
process_includes_biological_process
|
{
"id": "C0596290",
"name": "cell proliferation",
"pos": [
129,
147
]
}
|
{
"id": "C0026255",
"name": "mitoses",
"pos": [
162,
169
]
}
|
the mental status examination evaluates appearance and behavior , attitude , perception , orientation , judgment , cognition , abstraction and insight .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behavior",
"pos": [
55,
63
]
}
|
{
"id": "C0009240",
"name": "cognition",
"pos": [
115,
124
]
}
|
the kinetics of cell division and sister chromatid exchanges were studied in pha-stimulated short-term cultivations of peripheral blood by means of the budr/fpg technique in controls and in five patients with 45 , x/46 , x , i ( xq ) mosaicism .
|
process_includes_biological_process
|
{
"id": "C0007590",
"name": "the",
"pos": [
0,
3
]
}
|
{
"id": "C0037211",
"name": "sister chromatid exchanges",
"pos": [
34,
60
]
}
|
[ mitotic cycle of cells of regenerating rat liver in rna synthesis disturbed by actinomycin in the g1 period ] .
|
process_includes_biological_process
|
{
"id": "C1155839",
"name": "mitotic cycle",
"pos": [
2,
15
]
}
|
{
"id": "C0079395",
"name": "g1 period",
"pos": [
100,
109
]
}
|
[ the effect of biogenic amines on respiration and pulmonary circulation . i. acetylcholine inhalation and infusion in the right atrium and the truncus bicaroticus ] .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "respiration",
"pos": [
35,
46
]
}
|
{
"id": "C0004048",
"name": "inhalation",
"pos": [
92,
102
]
}
|
this calcification of the mitochondria may play a role in the neoplastic transformation of the cell , especially as far as it concerns metabolic behavior and the genetic specification of the permeability characteristics of the transformed cell membrane .
|
process_includes_biological_process
|
{
"id": "C0007621",
"name": "neoplastic",
"pos": [
62,
72
]
}
|
{
"id": "C1510411",
"name": "transformed",
"pos": [
227,
238
]
}
|
these results indicate that preferential transcription of certain chromatin genes relative to total rna synthesis can occur and that this process is dependent on the presence of chromosomal proteins .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
41,
54
]
}
|
{
"id": "C1328948",
"name": "rna synthesis",
"pos": [
100,
113
]
}
|
the hsv immune status of the donor had no effect on the ability of either cell population to mediate adcc .
|
process_includes_biological_process
|
{
"id": "C0020964",
"name": "immune status",
"pos": [
8,
21
]
}
|
{
"id": "C0003272",
"name": "adcc",
"pos": [
101,
105
]
}
|
the decrease in reproductive capacity of female offspring from mice treated with des during gestation was dose-related ;
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
16,
28
]
}
|
{
"id": "C0032961",
"name": "gestation",
"pos": [
92,
101
]
}
|
the addition of rnase inhibitor to transcription mixtures markedly increased the rate of rna synthesis .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
35,
48
]
}
|
{
"id": "C1328948",
"name": "rna synthesis",
"pos": [
89,
102
]
}
|
to evaluate observer bias as a possible factor influencing neonatal hearing testing , two trained observers were asked to evaluate the behavior of 200 neonates at a moment the observers thought a stimulus was being presented .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behavior",
"pos": [
135,
143
]
}
|
{
"id": "C0039869",
"name": "thought",
"pos": [
186,
193
]
}
|
the immune response of 21 ms patients and 21 healthy volunteers was tested in vitro lymphocyte transformation assay .
|
process_includes_biological_process
|
{
"id": "C0301872",
"name": "immune response",
"pos": [
4,
19
]
}
|
{
"id": "C0024262",
"name": "lymphocyte transformation",
"pos": [
84,
109
]
}
|
the diversity of the mechanisms of the controls of gene expression in the eukaryotic cells is discussed at different levels : a ) chromatin elimination , b ) polyploidisation , c ) polytenisation , d ) gene amplification , e ) gene magnification , f ) inactivation of genes by complexing with specific proteins and/or protamines , g ) transcription , h ) complex formation of transcriptional products with specific proteins , i ) release of the transcriptional products from the template containing strands , j ) processing of newly formed rna 's k ) intranuclear degradation of newly formed rna 's , l ) nucleocytoplasmic translocation , and m ) various forms of rna containing structures , including masked messenger rna 's and ribosome storages , in the cytoplasm .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene expression",
"pos": [
51,
66
]
}
|
{
"id": "C0040649",
"name": "transcriptional",
"pos": [
445,
460
]
}
|
temperature relations of aerial and aquatic respiration in six littoral snails in respiration in six littoral snails in relation to their vertical zonation .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "respiration",
"pos": [
44,
55
]
}
|
{
"id": "C0004048",
"name": "in respiration",
"pos": [
79,
93
]
}
|
purified sigma polypeptide was found to stimulate the transcription of phage dna while having little effect on rna synthesis with the synthetic dna poly ( da-dt ) as template .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
54,
67
]
}
|
{
"id": "C1328948",
"name": "rna",
"pos": [
111,
114
]
}
|
the inhibitory effect of delta protein on poly ( da-dt ) transcription was strongly dependent on the presence of kc1 in the rna synthesis reaction mixture .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
57,
70
]
}
|
{
"id": "C1328948",
"name": "rna synthesis",
"pos": [
124,
137
]
}
|
it has been asked , if hypothalamic lesions in man would cause alterations in instinct behaviour , which could be attributed to the instinct motivational systems .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behaviour",
"pos": [
87,
96
]
}
|
{
"id": "C0026605",
"name": "motivational",
"pos": [
141,
153
]
}
|
the results are interpreted in terms of several cell cycle models and suggest that the events controlling cell proliferation are sensitive to hydrocortisone modulation during the g1 and possibly the g2 periods .
|
process_includes_biological_process
|
{
"id": "C0596290",
"name": "cell",
"pos": [
48,
52
]
}
|
{
"id": "C0079396",
"name": "g2 periods",
"pos": [
199,
209
]
}
|
the conclusion is made that camp is involved in formation of the transcriptional complex much as it is involved in initiation of transcription in bacterial operons .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcriptional",
"pos": [
65,
80
]
}
|
{
"id": "C1158830",
"name": "initiation",
"pos": [
115,
125
]
}
|
thiethylperazine maleate , a classical antiemetic phenothiazine , displays dopaminergic antagonism in behavioral , neurochemical , and neuroendocrine systems , but is paradoxical insofar as it is thought not to possess clinical neuroleptic activity .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behavioral",
"pos": [
102,
112
]
}
|
{
"id": "C0039869",
"name": "thought",
"pos": [
196,
203
]
}
|
lightly anaesthetized and spontaneously breathing p. anubis ( pa ) and m. mulatta ( mm ) inhaled at ambient pressure 3.2 % oxygen ( identical to 37,500 ft or 11,430 m ) from air and also after pre-exposure to 14 % oxygen ( identical to 10,000 ft or 3,048 m ) .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "breathing",
"pos": [
40,
49
]
}
|
{
"id": "C0004048",
"name": "inhaled",
"pos": [
89,
96
]
}
|
the same respiratory effects were noted in a spontaneously breathing c6 spinal animal , while an artificially ventilated c1 spinal animal still displayed a powerful central inspiratory drive in its recurrent laryngeal electroneurogram .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "breathing",
"pos": [
59,
68
]
}
|
{
"id": "C0004048",
"name": "inspiratory",
"pos": [
173,
184
]
}
|
[ curve of labeled mitoses with different states of cell proliferation kinetics . v. effect of the circadian rhythm of cell proliferation on the shape of the labeled mitosis curve ] .
|
process_includes_biological_process
|
{
"id": "C0596290",
"name": "cell proliferation",
"pos": [
52,
70
]
}
|
{
"id": "C0026255",
"name": "mitosis",
"pos": [
166,
173
]
}
|
using a data set of women who longitudinally recorded menstrual and reproductive events , we examined menstrual cycle characteristics in relationship to early and late menarche , early and late menopause , and deferred parity , three variables epidemiologically related to breast cancer incidence .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
68,
80
]
}
|
{
"id": "C0025329",
"name": "menstrual cycle",
"pos": [
102,
117
]
}
|
molecular genetic analysis demonstrated loss of blur8 genes , expression of mouse macrophage specific genes , and enhanced transcription of h-2d and mouse beta 2-microglobulin genes in the aged cells , confirming that the hybrids ' macrophage properties were attributable to ns1 genes .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "expression",
"pos": [
62,
72
]
}
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
123,
136
]
}
|
understanding of toxicity and underlying mechanisms is enhanced when naturalistic behaviors are thought of as responses to stimuli .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behaviors",
"pos": [
82,
91
]
}
|
{
"id": "C0039869",
"name": "thought",
"pos": [
96,
103
]
}
|
definition of the normal pathways for growth stimulation and inhibition of epithelial cell growth by autocrine peptides like tgf beta and tgf alpha undoubtedly will increase understanding of normal growth and development , embryogenesis , wound repair , and tumorigenesis .
|
process_includes_biological_process
|
{
"id": "C0678723",
"name": "development",
"pos": [
209,
220
]
}
|
{
"id": "C0013936",
"name": "embryogenesis",
"pos": [
223,
236
]
}
|
in a test of this hypothesis , nerve growth factor ( ngf ) , which alters gene expression , increased nr at a time post-ngf coincident with increased activity of rna polymerases , while gaba , also postulated to alter transcription , increased nr with near instantaneous shifts of nucleolar positions within the nuclear space .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene expression",
"pos": [
74,
89
]
}
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
218,
231
]
}
|
the appearance of an mdr phenotype in these cells was linked to a decreased accumulation and increased efflux of the drug [ 3h ] vinblastine when compared to the drug-sensitive melanoma cell line .
|
process_includes_biological_process
|
{
"id": "C0242640",
"name": "mdr",
"pos": [
21,
24
]
}
|
{
"id": "C1512072",
"name": "efflux",
"pos": [
103,
109
]
}
|
the initial phase of transcription gave rise to specific changes in this footprint : the upstream border remained at the same position up to synthesis of a 4-nt rna chain , whereas at the downstream border progressive disappearance of hypersensitivity sites took place .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
21,
34
]
}
|
{
"id": "C1328948",
"name": "synthesis",
"pos": [
141,
150
]
}
|
this use of suggestion differs from the common use of the term suggestion , which is a logical offering for a change in behavior or thought .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behavior",
"pos": [
120,
128
]
}
|
{
"id": "C0039869",
"name": "thought",
"pos": [
132,
139
]
}
|
the accurate temporal expression of these genes indicates that both sets of hybrid embryos contain factors which regulate the timing of their transcription .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "expression",
"pos": [
22,
32
]
}
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
142,
155
]
}
|
these results suggest that heat shock stimulates a shift in energy metabolism to anaerobic glycolysis while at the same time causing an increase in the demand for atp .
|
process_includes_biological_process
|
{
"id": "C0014272",
"name": "energy",
"pos": [
60,
66
]
}
|
{
"id": "C0017952",
"name": "anaerobic glycolysis",
"pos": [
81,
101
]
}
|
the local humoral immune response in transplant patients with pneumonitis was not specific to the infecting agent and is most probably the result of polyclonal b cell activation or facilitated transport of igg from serum to lung secretions .
|
process_includes_biological_process
|
{
"id": "C0020967",
"name": "humoral immune response",
"pos": [
10,
33
]
}
|
{
"id": "C1155003",
"name": "b cell activation",
"pos": [
160,
177
]
}
|
observations were made on respiration , alveolar concentration of co2 , arterial blood pressure and heart rate in barbiturate-anesthetized cats subjected routinely to section of the vagus and carotid sinus nerves and maintained with pure o2 for inhalation .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "respiration",
"pos": [
26,
37
]
}
|
{
"id": "C0004048",
"name": "inhalation",
"pos": [
245,
255
]
}
|
in vitro transcription from a gd promoter construct containing multiple binding sites showed increased rna synthesis in the presence of partially purified icp4 .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
9,
22
]
}
|
{
"id": "C1328948",
"name": "rna",
"pos": [
103,
106
]
}
|
ventilatory response during external dead space ( tube ) breathing and co2 inhalation for given increase in petco2 were compared at different levels of peto2 ( hyperoxia , normoxia , and hypoxia ) in human subjects .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "breathing",
"pos": [
57,
66
]
}
|
{
"id": "C0004048",
"name": "inhalation",
"pos": [
75,
85
]
}
|
in an attempt to know more about its mechanism of action we describe here its inhibitory activity on cell division , 3h-thymidine incorporation and on cell cycle progression .
|
process_includes_biological_process
|
{
"id": "C0007590",
"name": "cell division",
"pos": [
101,
114
]
}
|
{
"id": "C1516334",
"name": "cell cycle progression",
"pos": [
151,
173
]
}
|
expression of the troponin complex genes : transcriptional coactivation during myoblast differentiation and independent control in heart and skeletal muscles .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "expression",
"pos": [
0,
10
]
}
|
{
"id": "C0040649",
"name": "transcriptional",
"pos": [
43,
58
]
}
|
transcription of c-myc gene sequences with purified mammalian rna polymerase ii revealed several sites of transcription termination and pausing in the vicinity of the exon 1-intron 1 junction .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
0,
13
]
}
|
{
"id": "C0597600",
"name": "transcription termination",
"pos": [
106,
131
]
}
|
unlike transcriptional enhancer elements , ivs2 failed to increase stable rna production when it was placed downstream of the polyadenylation site .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcriptional",
"pos": [
7,
22
]
}
|
{
"id": "C0949765",
"name": "polyadenylation",
"pos": [
126,
141
]
}
|
in conjunction with the a-box intragenic control region , this upstream transcription-modulatory region functions in the selection mechanism for the site of transcription initiation .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
72,
85
]
}
|
{
"id": "C1158830",
"name": "transcription initiation",
"pos": [
157,
181
]
}
|
since the transcription-modulatory region directs the position of the start site and the actual sequence of the transcription-modulatory region determines the level of trnaasn gene transcription , the possibility is raised that the transcription-modulatory region directs a transcription initiation event similar to open complex formation at procaryotic promoters .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
10,
23
]
}
|
{
"id": "C1158830",
"name": "transcription initiation",
"pos": [
274,
298
]
}
|
the data are discussed in connection with the development of thalamos -- frontal associative brain system which participates in the behavioral program formation based on current biological motivation .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behavioral",
"pos": [
132,
142
]
}
|
{
"id": "C0026605",
"name": "motivation",
"pos": [
189,
199
]
}
|
on the other hand , in vitro study of proliferative and cytotoxic components of cell-mediated immunity by mixed lymphocyte reaction and cell-mediated lympholysis , respectively , showed that the proliferative reactivity remained unimpaired whereas the cytotoxic reactivity was clearly inhibited in the tested animals .
|
process_includes_biological_process
|
{
"id": "C0020966",
"name": "cell-mediated immunity",
"pos": [
80,
102
]
}
|
{
"id": "C0301896",
"name": "cell-mediated lympholysis",
"pos": [
136,
161
]
}
|
intrauterine streptococcal infection of albino rats hematogenically during pregnancy ( implantation , placentation ) leads to different disorders of the bioelectrical activity of the uterus , which become normalized after the institution of pulsating local negative pressure with periodic oxygen supply .
|
process_includes_biological_process
|
{
"id": "C0032961",
"name": "pregnancy",
"pos": [
75,
84
]
}
|
{
"id": "C0032058",
"name": "placentation",
"pos": [
102,
114
]
}
|
a study was designed to gain information on the concerns , attitudes , beliefs , and knowledge that women have about reproduction to determine how these affect their health practices during pregnancy .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproduction",
"pos": [
117,
129
]
}
|
{
"id": "C0032961",
"name": "pregnancy",
"pos": [
190,
199
]
}
|
ne-induced respiration was stable for 60-120 min and was inhibited by reduction of the oxygen concentration in the medium much more than respiration induced by the addition of respiratory substrates .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "respiration",
"pos": [
11,
22
]
}
|
{
"id": "C0004048",
"name": "in",
"pos": [
149,
151
]
}
|
it was concluded that the presence of the thymus per se is not required for infection and oncogenesis by felv and that feline t lymphocytes may be transformed after peripheralization to other tissues .
|
process_includes_biological_process
|
{
"id": "C0007621",
"name": "oncogenesis",
"pos": [
90,
101
]
}
|
{
"id": "C1510411",
"name": "transformed",
"pos": [
147,
158
]
}
|
neoplastic transformation has been demonstrated for a 1-methylguanine-derived line , and both 1-methylguanine- and 7-methylguanine-treated cell lines exhibit characteristics similar to those of chinese hamster cells transformed with the carcinogen 3,4-benzopyrene or the dna tumor virus sv40 .
|
process_includes_biological_process
|
{
"id": "C0007621",
"name": "neoplastic transformation",
"pos": [
0,
25
]
}
|
{
"id": "C1510411",
"name": "transformed",
"pos": [
216,
227
]
}
|
these studies demonstrate that in the autochthonous host the measurement of host immune status by in vivo cell-mediated immune responses to exogenous antigens does not necessarily predict the host response to tumor growth .
|
process_includes_biological_process
|
{
"id": "C0020964",
"name": "immune status",
"pos": [
81,
94
]
}
|
{
"id": "C0301872",
"name": "host response",
"pos": [
192,
205
]
}
|
in a purified transcription system , the cro protein is an effective and specific repressor of rna synthesis from the n and cro genes ;
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
14,
27
]
}
|
{
"id": "C1328948",
"name": "rna synthesis",
"pos": [
95,
108
]
}
|
a frequency count was also made of nine classroom behaviors thought to be influenced by self-concept .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behaviors",
"pos": [
50,
59
]
}
|
{
"id": "C0039869",
"name": "thought",
"pos": [
60,
67
]
}
|
the program is based on an educational , behavioral , social systems model , where `` '' educational '' '' refers directly to teaching skills which a person lacks , `` '' behavioral '' '' deals with providing the motivation to perform these skills and to precisely operationalize and measure the effectiveness of the steps in learning them , and `` '' social systems '' '' describes influencing clients ' social environments in their interests .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "`` '' behavio",
"pos": [
165,
178
]
}
|
{
"id": "C0026605",
"name": "the motiva",
"pos": [
209,
219
]
}
|
these peptides affect the behaviour by a temporary selective increase in the state of arousal in limbic midbrain structures , thereby increasing the motivational influence of environmental stimuli .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behaviour",
"pos": [
26,
35
]
}
|
{
"id": "C0026605",
"name": "motivational",
"pos": [
149,
161
]
}
|
[ growth and reproduction of the chinchilla-age at vaginal opening , oestrous cycle , gestation period , litter size , sex ratio , and diseases frequently encountered ( author 's transl ) ] .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproduction",
"pos": [
13,
25
]
}
|
{
"id": "C0025329",
"name": "oestrous",
"pos": [
69,
77
]
}
|
since trf must be added at the start of culture , the initiation of b-cell maturation into igg secretion by trf occurs during b-cell proliferation , and is followed by further proliferation before igg antibody can be detected .
|
process_includes_biological_process
|
{
"id": "C1511002",
"name": "b-cell maturation",
"pos": [
68,
85
]
}
|
{
"id": "C1155008",
"name": "b-cell proliferation",
"pos": [
126,
146
]
}
|
host defenses in experimental scrub typhus : role of spleen and peritoneal exudate lymphocytes in cellular immunity .
|
process_includes_biological_process
|
{
"id": "C0520990",
"name": "host defenses",
"pos": [
0,
13
]
}
|
{
"id": "C0020966",
"name": "cellular immunity",
"pos": [
98,
115
]
}
|
it may also affect transcription , because it stimulated total rna synthesis up to 50 % in this in vitro system .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
19,
32
]
}
|
{
"id": "C1328948",
"name": "rna synthesis",
"pos": [
63,
76
]
}
|
independence of post-fertilization respiration in the sea-urchin egg from the level of respiration before fertilization .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "respiration",
"pos": [
35,
46
]
}
|
{
"id": "C0004048",
"name": "in",
"pos": [
62,
64
]
}
|
systemic immune responses were assayed after skin and eye infections by means of the lymphocyte transformation ( lt ) and complement fixation ( cf ) tests .
|
process_includes_biological_process
|
{
"id": "C0301872",
"name": "immune responses",
"pos": [
9,
25
]
}
|
{
"id": "C0024262",
"name": "lymphocyte transformation",
"pos": [
85,
110
]
}
|
the etiology of both leydig cell hyperplasia and reproductive testicular maturation in the absence of significant gonadotropin secretion remains to be established .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
49,
61
]
}
|
{
"id": "C0678723",
"name": "maturation",
"pos": [
73,
83
]
}
|
studies with isolated nuclei show that x and y gene expression is regulated by hormones at the level of transcription .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene",
"pos": [
47,
51
]
}
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
104,
117
]
}
|
reproductive efficiency can be increased in farm animals by decreasing the interval from parturition to conception .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
0,
12
]
}
|
{
"id": "C0009637",
"name": "conception",
"pos": [
104,
114
]
}
|
a long-term kinetic study of the immune response of four calves experimentally infected with a m. avium strain was made using the following tests : lymphocyte stimulation ( ls ) , leukocyte migrationinhibition ( lmi ) , delayed skin hypersensitivity ( dhs ) , and a radioimmunoassay ( ria ) procedure for antibodies to m. avium .
|
process_includes_biological_process
|
{
"id": "C0301872",
"name": "immune response",
"pos": [
33,
48
]
}
|
{
"id": "C0024262",
"name": "lymphocyte",
"pos": [
148,
158
]
}
|
thirty six buffalo showing normal reproductive cyclas were given a single intramuscular injection of prostaglandin f ( 2alpha ) - thamsalt ( pgf ( 2alpha ) ) and estrumate on day 9 or 15 of the estrous cycle in order to induce estrus .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
34,
46
]
}
|
{
"id": "C0025329",
"name": "estrous cycle",
"pos": [
194,
207
]
}
|
cows in poor body condition and receiving 18 mcal of supplemental energy per head per day had increased ( p < .05 ) reproductive performance as evidenced by an increase in the pregnancy rate , pregnancy rate at first service , and percentage of conceptions per estrus when compared to the other groups .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
116,
128
]
}
|
{
"id": "C0009637",
"name": "conceptions",
"pos": [
245,
256
]
}
|
we have determined the time of appearance and maturation of these properties during embryonic development .
|
process_includes_biological_process
|
{
"id": "C0678723",
"name": "maturation",
"pos": [
46,
56
]
}
|
{
"id": "C0013936",
"name": "embryonic development",
"pos": [
84,
105
]
}
|
we found that following the reproductive counselling session couples developed a much more realistic attitude towards the subsequent pregnancy and their anxiety was considerably lessened .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
28,
40
]
}
|
{
"id": "C0032961",
"name": "pregnancy",
"pos": [
133,
142
]
}
|
in this in vitro system , the stimulation by ihf of cii and o gene expression is at the level of transcription .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene",
"pos": [
62,
66
]
}
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
97,
110
]
}
|
[ effects of the type of respiration ( spontaneous , assisted , with positive expiratory pressure ) on the frequency of gas embolism in sitting position surgery ] .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "respiration",
"pos": [
25,
36
]
}
|
{
"id": "C0231800",
"name": "expiratory",
"pos": [
78,
88
]
}
|
in order to elucidate the role of hormones and other factors on the maturation of absorptive cells ( maturation phase ) in the fetal rodent in organ culture , we have taken the explants after the organogenesis phase .
|
process_includes_biological_process
|
{
"id": "C0678723",
"name": "maturation",
"pos": [
68,
78
]
}
|
{
"id": "C0242290",
"name": "organogenesis",
"pos": [
196,
209
]
}
|
on the other hand , the activity of purified chromatin as a template for transcription by added , partially purified rna polymerase ii was significantly reduced , suggesting that carcinogen-induced damage to chromatin was the cause of the observed inhibition of heterogeneous rna synthesis .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
73,
86
]
}
|
{
"id": "C1514672",
"name": "of",
"pos": [
259,
261
]
}
|
in comparison to ovaries cultured with tonic lh , an lh pulse `` '' rescued '' '' follicles from atresia , induced thecal cell proliferation , and increased the rate at which granulosa cells enter mitosis .
|
process_includes_biological_process
|
{
"id": "C0596290",
"name": "l cell proliferati",
"pos": [
120,
138
]
}
|
{
"id": "C0026255",
"name": "mitos",
"pos": [
197,
202
]
}
|
mapping of in vitro elongated nascent transcripts to amy-2a restriction fragments indicates that transcription terminates in a region between 2.5 and 4 kb downstream of the polyadenylation site .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
97,
110
]
}
|
{
"id": "C0949765",
"name": "polyadenylation",
"pos": [
173,
188
]
}
|
these runoff transcription experiments , combined with s1 nuclease mapping of nuclear transcripts at steady state , suggest that transcription termination occurs at multiple sites .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
13,
26
]
}
|
{
"id": "C0597600",
"name": "transcription termination",
"pos": [
129,
154
]
}
|
in five spontaneously breathing anesthetized cats , we determined the inspiratory elastic ( wel ) , resistive ( wres ) , and total ( wi ) mechanical work rates ( power ) during control and first loaded inspirations through graded linear resistances ( delta r ) by `` '' campbell diagrams '' '' based on measurement of esophageal pressure .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "breathing",
"pos": [
22,
31
]
}
|
{
"id": "C0004048",
"name": "inspiratory",
"pos": [
70,
81
]
}
|
this model was tested on recordings of the emgdi that were obtained from an esophageal electrode in five normal subjects breathing to fatigue through an inspiratory resistor .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "breathing",
"pos": [
121,
130
]
}
|
{
"id": "C0004048",
"name": "inspiratory",
"pos": [
153,
164
]
}
|
s1 nuclease mapping reveals that transcription starts 149 nucleotides upstream of the initiation codon and that the site of polyadenylation is located 200 nucleotides downstream of the termination codon .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
33,
46
]
}
|
{
"id": "C0949765",
"name": "polyadenylation",
"pos": [
124,
139
]
}
|
a transcriptional enhancer element , located 3 ' to the polyadenylation site for the viral rnas expressed in transformed cells , has previously been shown to be essential for transformation ( lusky et al. , mol .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcriptional",
"pos": [
2,
17
]
}
|
{
"id": "C0949765",
"name": "polyadenylation",
"pos": [
56,
71
]
}
|
mt-141 did not change parameters of reproductive study in birth , development , physiological function and behavior of f1 rat .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
36,
48
]
}
|
{
"id": "C0678723",
"name": "development",
"pos": [
66,
77
]
}
|
induction of local immunity and specific systemic tolerance seems to be a characteristic immune response of the gut-associated lymphoid tissue ( galt ) .
|
process_includes_biological_process
|
{
"id": "C0020964",
"name": "immunity",
"pos": [
19,
27
]
}
|
{
"id": "C0301872",
"name": "immune response",
"pos": [
89,
104
]
}
|
we show that in these operons the main polarity effect is essentially transcriptional and the camp-cap complex decreases polarity by interfering with premature transcription termination .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcriptional",
"pos": [
70,
85
]
}
|
{
"id": "C0597600",
"name": "transcription termination",
"pos": [
160,
185
]
}
|
these data indicate that control of type i collagen gene expression is a complex process which is exerted at both transcriptional and post-transcriptional levels .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene expression",
"pos": [
52,
67
]
}
|
{
"id": "C0040649",
"name": "transcriptional",
"pos": [
139,
154
]
}
|
the cultures were harvested 75 h after culture initiation , and second-division cells were scored for induction of sces according to established procedures .
|
process_includes_biological_process
|
{
"id": "C0007590",
"name": "division",
"pos": [
71,
79
]
}
|
{
"id": "C0037211",
"name": "sces",
"pos": [
115,
119
]
}
|
tests of behavioral interventions seldom examine changes in health beliefs and behaviors thought to be prerequisites of improved outcome health states and they do not attempt to specify how patient characteristics or pretest measures influence responses to the intervention .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behaviors",
"pos": [
79,
88
]
}
|
{
"id": "C0039869",
"name": "thought",
"pos": [
89,
96
]
}
|
using in vitro nuclear run-on transcription with nuclei prepared from mcf-7 cells grown in the presence of estradiol or in estradiol-stripped medium , we demonstrate here that expression of the ps2 gene is controlled by estrogen at the transcriptional level .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "expression",
"pos": [
176,
186
]
}
|
{
"id": "C0040649",
"name": "transcriptional",
"pos": [
236,
251
]
}
|
transcription of a cloned rat rdna containing the transcription initiation region was studied using purified fractions derived from whole cell extract .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
0,
13
]
}
|
{
"id": "C1158830",
"name": "transcription initiation",
"pos": [
50,
74
]
}
|
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