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[ language-thought project in utrecht . a developmental psychology study on the effect of instruction in oral use of language on language behavior and thinking capacity in toddlers ] .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behavior",
"pos": [
138,
146
]
}
|
{
"id": "C0039869",
"name": "thinking",
"pos": [
151,
159
]
}
|
host defense against bacterial endotoxemia-contribution of the early and late components of complement to detoxification .
|
process_includes_biological_process
|
{
"id": "C0520990",
"name": "host defense",
"pos": [
0,
12
]
}
|
{
"id": "C0025516",
"name": "detoxification",
"pos": [
106,
120
]
}
|
after pulse exposure to concentrations of actinomycin d ( amd ) sufficient to abolish transcription , vero cells recover rna synthesis much more rapidly than most other cell types .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
86,
99
]
}
|
{
"id": "C1328948",
"name": "rna synthesis",
"pos": [
121,
134
]
}
|
alteration of cerebral function in man produced by diffusion respiration and prolonged inhalation of carbon dioxide .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "respiration",
"pos": [
61,
72
]
}
|
{
"id": "C0004048",
"name": "inhalation",
"pos": [
87,
97
]
}
|
in 8 patients with chronic peritoneal dialysis before and after 24-hour peritoneal dialysis examinations on the cellular immunity were performed ( lymphocyte blast transformation with pha and con a , adcc ) .
|
process_includes_biological_process
|
{
"id": "C0020966",
"name": "cellular immunity",
"pos": [
112,
129
]
}
|
{
"id": "C0003272",
"name": "adcc",
"pos": [
200,
204
]
}
|
thus , the decrease in enzymatic dna methylation correlates with the presence of new transcriptional products suggesting that this modification process inversely correlates with the initiation of transcription .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcriptional",
"pos": [
85,
100
]
}
|
{
"id": "C1158830",
"name": "initiation",
"pos": [
182,
192
]
}
|
the role of maternal diabetes as a cause of repetitive early pregnancy loss was evaluated by examining the reproductive performance of 154 diabetic patients in 489 pregnancies .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
107,
119
]
}
|
{
"id": "C0032961",
"name": "pregnancies",
"pos": [
164,
175
]
}
|
it consists of nine subscales on which client 's attitudes and behaviors in such psychosocial areas as motivation , self-concept , and family functioning can be rated by clinicians .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behaviors",
"pos": [
63,
72
]
}
|
{
"id": "C0026605",
"name": "motivation",
"pos": [
103,
113
]
}
|
a genetic approach to the role of energy metabolism in the growth of tumor cells : tumorigenicity of fibroblast mutants deficient either in glycolysis or in respiration .
|
process_includes_biological_process
|
{
"id": "C0014272",
"name": "energy metabolism",
"pos": [
34,
51
]
}
|
{
"id": "C0017952",
"name": "glycolysis",
"pos": [
140,
150
]
}
|
finally , concerning the issue of responsibility , i suggest that behavioral scientists must assume responsibility , as well , for providing relevant expertise in research and development of necessary motivation and communication skills .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behavioral",
"pos": [
66,
76
]
}
|
{
"id": "C0026605",
"name": "motivation",
"pos": [
201,
211
]
}
|
it is suggested that , because suppressor activity appears dominant in the naive state of the immune system , the induction of specific abrosuppressor activity may be essential if an immune response is to take place .
|
process_includes_biological_process
|
{
"id": "C0020964",
"name": "state",
"pos": [
81,
86
]
}
|
{
"id": "C0301872",
"name": "immune response",
"pos": [
183,
198
]
}
|
the paper reviews mathematical models of immunological processes associated with reactions of the total immunity system and its single formations : infectious diseases , in vivo experiments with cell cultures , cell proliferation and differentiation in the thymus , primary and secondary immune responses to the antigen , immunodeficient states , etc .
|
process_includes_biological_process
|
{
"id": "C0020964",
"name": "immunity",
"pos": [
104,
112
]
}
|
{
"id": "C0301872",
"name": "immune responses",
"pos": [
288,
304
]
}
|
studies of the effects of nasal respiration on the lower respiratory tract , and on metabolic processes generally , have largely been confined to those occurring during inspiration .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "respiration",
"pos": [
32,
43
]
}
|
{
"id": "C0004048",
"name": "inspiration",
"pos": [
169,
180
]
}
|
thus , the oncovirus gene expression is restricted in the non-permissive tumor cells , unlike of the permissive chicken rous sarcoma cells , both in the level of transcription , and in the processing and transfer v-mrnas from nucleus to cytoplasm .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene",
"pos": [
21,
25
]
}
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
162,
175
]
}
|
the results suggest that the effect of w-7 on cell proliferation might be through selective inhibition of the g1/s boundary phase , which is similar to the effect of excess thymidine .
|
process_includes_biological_process
|
{
"id": "C0596290",
"name": "cell proliferation",
"pos": [
46,
64
]
}
|
{
"id": "C0079395",
"name": "g1",
"pos": [
110,
112
]
}
|
the only cell-division mutations not to affect meiosis were in three cytokinesis loci and in one budemergence locus .
|
process_includes_biological_process
|
{
"id": "C0007590",
"name": "cell-division",
"pos": [
9,
22
]
}
|
{
"id": "C0010813",
"name": "cytokinesis",
"pos": [
69,
80
]
}
|
since cytomegalovirus ( cmv ) infections may alter host defense against a variety of pathogens , phagocytosis , oxygen uptake , and h2o2 release by pulmonary macrophages obtained from guinea pigs with acute cmv interstitial pneumonia were evaluated .
|
process_includes_biological_process
|
{
"id": "C0520990",
"name": "host defense",
"pos": [
51,
63
]
}
|
{
"id": "C0031308",
"name": "phagocytosis",
"pos": [
97,
109
]
}
|
we also examine the effect of the auxiliary transcription factor nusa on transcription of these mutants , and we provide support for the proposal that specific effects of nusa on transcription termination require a sequence known as `` '' boxa '' '' ( olson , e.r. , flamm , e.l. , and friedman , d.i . ( 1982 ) cell 31 , 61-70 ) .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
44,
57
]
}
|
{
"id": "C0597600",
"name": "transcription termination",
"pos": [
179,
204
]
}
|
to study [ 3h ] 5-ht binding site regulation and development , various serotonergic compounds were injected into the chorioallantoic fluid of the eggs at different times during embryonic development .
|
process_includes_biological_process
|
{
"id": "C0678723",
"name": "development",
"pos": [
49,
60
]
}
|
{
"id": "C0013936",
"name": "embryonic",
"pos": [
177,
186
]
}
|
the soluble system retained properties of transcription characteristic of intact viral cores , including ( i ) similar relative rates of initiation of various genes , ( ii ) multiple requirement for atp , ( iii ) methylation and polyadenylation of transcripts , and ( iv ) inhibition by a topoisomerase antagonist .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
42,
55
]
}
|
{
"id": "C0949765",
"name": "polyadenylation",
"pos": [
229,
244
]
}
|
published ultraviolet ( uv ) inactivation data and in vitro transcription studies have suggested that vesicular stomatitis virus ( vsv ) leader rna was solely responsible for the inhibition of host cell rna synthesis by this virus .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
60,
73
]
}
|
{
"id": "C1514672",
"name": "inhibition of",
"pos": [
179,
192
]
}
|
although at 39 degrees the vsv mutant tsg22 could undergo only primary transcription , maximum inhibition of host cell rna synthesis took place .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
71,
84
]
}
|
{
"id": "C1514672",
"name": "inhibition of",
"pos": [
95,
108
]
}
|
in both cell lines , a very similar slow down in cell proliferation was observed after treatment , as indicated by a high number of mitoses from the first and second mitotic cycle .
|
process_includes_biological_process
|
{
"id": "C0596290",
"name": "cell",
"pos": [
8,
12
]
}
|
{
"id": "C0026255",
"name": "mitotic cycle",
"pos": [
166,
179
]
}
|
the region necessary for expression of the cck gene fusions in cos-7 cells is within 144 bases 5 ' to the initiation of transcription .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "expression",
"pos": [
25,
35
]
}
|
{
"id": "C1158830",
"name": "initiation",
"pos": [
106,
116
]
}
|
these results , together with the isolation of a large complex containing all necessary transcription components , emphasize the importance of the interaction of these components for both stable complex formation and transcription initiation .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
88,
101
]
}
|
{
"id": "C1158830",
"name": "transcription initiation",
"pos": [
217,
241
]
}
|
( yanofsky , c. , das , a. , fisher , r. , kolter , r. , and berlin , v. ( 1984 ) ucla symposium of gene expression ( hamer , d. , and rosenberg , m. , eds ) pp . 295-310 , alan r. liss , inc. , new york ) in which transcriptional pausing after the synthesis of the 1:2 stem-loop closely couples transcription and translation of the leader region .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene expression",
"pos": [
100,
115
]
}
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
296,
309
]
}
|
these findings may reflect changes in growth control mechanisms which accompany kidney epithelial cell tumorigenesis and suggest that the study of transformed lines derived in this manner could lead to the identification of in vitro properties which are associated with malignancy .
|
process_includes_biological_process
|
{
"id": "C0007621",
"name": "tumorigenesis",
"pos": [
103,
116
]
}
|
{
"id": "C1510411",
"name": "transformed",
"pos": [
147,
158
]
}
|
induction of protective immunity against schistosoma mansoni by a nonliving vaccine is dependent on the method of antigen presentation .
|
process_includes_biological_process
|
{
"id": "C0020964",
"name": "immunity",
"pos": [
24,
32
]
}
|
{
"id": "C0206431",
"name": "antigen presentation",
"pos": [
114,
134
]
}
|
there were three different response groups for a g1 phase block induced by 400 rad of x-rays : ( 1 ) minimal or no g1 block was observed in at homozygote cell strains ;
|
process_includes_biological_process
|
{
"id": "C0079395",
"name": "g1 phase",
"pos": [
49,
57
]
}
|
{
"id": "C1517342",
"name": "g1",
"pos": [
115,
117
]
}
|
such processes in drosophila melanogaster could be responsible for the maintenance of segment boundaries , the morphogenesis of metamorphosing imaginal disks , and the paths of axon outgrowth during neurogenesis .
|
process_includes_biological_process
|
{
"id": "C0026559",
"name": "morphogenesis",
"pos": [
111,
124
]
}
|
{
"id": "C0814002",
"name": "neurogenesis",
"pos": [
199,
211
]
}
|
maximizing gene expression from plasmid vectors containing the lambda pl promoter : strategies for overproducing transcription termination factor rho .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene expression",
"pos": [
11,
26
]
}
|
{
"id": "C0597600",
"name": "transcription termination",
"pos": [
113,
138
]
}
|
when related to pepck gene expression , the sequential loss of methyl groups demonstrates an early stage prior to transcription characterized by hypomethylation of discrete sites and a later developmental hypomethylation of all sites associated with the mature active pepck gene around the time of birth .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene expression",
"pos": [
22,
37
]
}
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
114,
127
]
}
|
the experimental analysis of behavior has lagged far behind mainstream psychology , particularly cognitive psychology , in the study of complex behavior-remembering , thinking , imaging , problem solving , and the like .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behavior",
"pos": [
29,
37
]
}
|
{
"id": "C0039869",
"name": "thinking",
"pos": [
167,
175
]
}
|
birth and infant death certificates for louisiana in 1972 were matched and reviewed to identify groups particularly in need of close medical support and counselling during the identify groups particularly in need of close medical support and counselling during the life phases of preparation for reproduction , gestation , and parenthood .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproduction",
"pos": [
296,
308
]
}
|
{
"id": "C0032961",
"name": "gestation",
"pos": [
311,
320
]
}
|
apart from the clinical protocol , psychometric test for the assessment of social behaviour and thought disorders were used .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behaviour",
"pos": [
82,
91
]
}
|
{
"id": "C0039869",
"name": "thought",
"pos": [
96,
103
]
}
|
the ratio of the respiration rate of intact levomycetin-treated cells to the content of cytochromes a , b , c was 1.15-1.55 times as low as that of control cells which is probably due to the tendency of respiration components to the independent translocation in the membrane and is the result of the decrease in the concentration of the respiration components under the less than fattening greater than of the membrane .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "respiration",
"pos": [
17,
28
]
}
|
{
"id": "C0004048",
"name": "in",
"pos": [
386,
388
]
}
|
the episome-dependent block of t7 gene expression was observed only in intact cells and detailed kinetics of gene expression in vivo revealed a stop of all transcription and translation at or just before 11 min after t7 infection .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene",
"pos": [
34,
38
]
}
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
156,
169
]
}
|
these results and the data on uv sensitivity of the mutants indicate that ( 1 ) the products of all these rec genes are related to uv resistance of the cell viability and are factors functioning through mechanisms other than excision repair , ( 2 ) the products of reca , recb and rec-4 genes display some roles in maintenance of a level of excision repair activity , and ( 3 ) the product of the rec-80 gene does not participate at all in excision repair .
|
process_includes_biological_process
|
{
"id": "C0007620",
"name": "cell",
"pos": [
152,
156
]
}
|
{
"id": "C0015249",
"name": "excision repair",
"pos": [
440,
455
]
}
|
from this behaviour , it is thought that these abnormal cells are true mutants which could be used in mutation research .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behaviour",
"pos": [
10,
19
]
}
|
{
"id": "C0039869",
"name": "thought",
"pos": [
28,
35
]
}
|
these consisted in a rearrangement of the enzyme activity pattern of energy-supplying metabolism , e.g . decrease in glycogenolytic and glycolytic enzyme activities and severalfold increase in key enzymes of aerobic endoxidation of substrates in beta-oxidation and the citric acid cycle .
|
process_includes_biological_process
|
{
"id": "C0014272",
"name": "energy",
"pos": [
69,
75
]
}
|
{
"id": "C0017952",
"name": "glycolytic",
"pos": [
136,
146
]
}
|
paper electrophoresis was employed to analyze changes taking place in the composition of the blood serum protein fractions of pigeons following an experimental reproduction in them of toxinfection caused by cl . perfringens , type a , and also upon exposure of the pigeons to a high and low temperature , as factors conducive to the development of toxinfection .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproduction",
"pos": [
160,
172
]
}
|
{
"id": "C0678723",
"name": "development",
"pos": [
333,
344
]
}
|
these questions concern the hypothalamic control of the lth secretion , the regression of the reproductive organs , the significance of that cyclic testosterone secretion by the ovaries recently reported , and the importance of hcg in the establishment of pregnancy and in proliferation of mammary tissue .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
94,
106
]
}
|
{
"id": "C0032961",
"name": "pregnancy",
"pos": [
256,
265
]
}
|
female presents , a behavior often used by others as an indicator of female sexual motivation , did not show corresponding changes under either test condition .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behavior",
"pos": [
20,
28
]
}
|
{
"id": "C0026605",
"name": "motivation",
"pos": [
83,
93
]
}
|
effect of oligomycin on the oxygen uptake at the 4th state of the respiration chain in mitochondria with the stable coupling of respiration and phosphorylation is studied .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "respiration",
"pos": [
66,
77
]
}
|
{
"id": "C0004048",
"name": "in",
"pos": [
121,
123
]
}
|
neoplastic transformation of mouse embryo cells by virus released from tumorigenic mouse cells transformed by avian sarcoma virus b77 .
|
process_includes_biological_process
|
{
"id": "C0007621",
"name": "neoplastic transformation",
"pos": [
0,
25
]
}
|
{
"id": "C1510411",
"name": "transformed",
"pos": [
95,
106
]
}
|
the relations between the determination of the gene est-6 expression and its transcription and translation were assessed by studying the effect of the inhibitors of rna ( actinomycin d ) and protein synthesis ( cycloheximide ) .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene",
"pos": [
47,
51
]
}
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
77,
90
]
}
|
during the histogenesis of retina in anurans both the reproduction and the onset of differentiation of different cell types take place .
|
process_includes_biological_process
|
{
"id": "C0178679",
"name": "histogenesis",
"pos": [
11,
23
]
}
|
{
"id": "C0007589",
"name": "differentiation",
"pos": [
84,
99
]
}
|
it appeared that a ) the test system aimed at reproduction and development was more sensitive than the subchronic study for 35 % of the selected compounds and was equally sensitive for another 35 % ;
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproduction",
"pos": [
46,
58
]
}
|
{
"id": "C0678723",
"name": "development",
"pos": [
63,
74
]
}
|
it was concluded that there was no evidence that anaesthesia , or surgery , impaired this aspect of the immune response in our patients , but the design of the experiments does not allow comment on other aspects of the immune response such as antigen presentation , immunoregulation and effector mechanisms , which are superimposed on the basic clonal expansion mechanisms studied in this investigation .
|
process_includes_biological_process
|
{
"id": "C0301872",
"name": "immune response",
"pos": [
104,
119
]
}
|
{
"id": "C0206431",
"name": "antigen",
"pos": [
243,
250
]
}
|
treatment of x-irradiated stationary ehrlich ascites tumour cells with the dna synthesis inhibitor beta-ara a ( 120 mumol/l , 30 min before and for 7 hours after irradiation ) is shown to lead to a large increase in the incidence of anaphase chromosome abnormalities ( anaphase bridges and fragments ) at the first mitosis following irradiation .
|
process_includes_biological_process
|
{
"id": "C0007590",
"name": "cells",
"pos": [
60,
65
]
}
|
{
"id": "C0026255",
"name": "mitosis",
"pos": [
315,
322
]
}
|
from these results we conclude that sucrose in the medium primarily regulates ompf gene expression , which in turn regulates ompc gene expression at the transcriptional level .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene",
"pos": [
83,
87
]
}
|
{
"id": "C0040649",
"name": "transcriptional",
"pos": [
153,
168
]
}
|
we analyzed expression of milk protein genes at the transcriptional , translation and posttranslational levels in progesterone-depleted medium in the presence or absence of prolactin .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "expression",
"pos": [
12,
22
]
}
|
{
"id": "C0040649",
"name": "transcriptional",
"pos": [
52,
67
]
}
|
the block in milk protein gene expression was not restricted to translational or posttranslational events but also included transcription , since no casein mrna accumulated in these cells .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene expression",
"pos": [
26,
41
]
}
|
{
"id": "C1519614",
"name": "translational",
"pos": [
85,
98
]
}
|
the block in milk protein gene expression was not restricted to translational or posttranslational events but also included transcription , since no casein mrna accumulated in these cells .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene expression",
"pos": [
26,
41
]
}
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
124,
137
]
}
|
further analysis revealed that mothers who breast-fed during the 6-week postpartum period differed from those who bottle-fed exclusively during this period on a number of behavioral beliefs , outcome evaluations , and normative beliefs , and on one measure of motivation to comply .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behavioral",
"pos": [
171,
181
]
}
|
{
"id": "C0026605",
"name": "motivation",
"pos": [
260,
270
]
}
|
using an in vitro phage assembly assay to measure in vivo expression of tail protein from these plasmids and in vitro transcription reactions to measure transcriptional template activity of dna fragments isolated from these plasmids , we have identified a region of dna between gene ant and gene 9 that behaves as a transcription termination signal .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
118,
131
]
}
|
{
"id": "C0597600",
"name": "transcription termination",
"pos": [
316,
341
]
}
|
during the study the following circulatory variables were studied : mean systemic arterial pressure , mean pulmonary arterial pressure , wedge pressure , heart rate , cardiac output , systolic and diastolic left ventricular pressure , stroke volume , total systemic resistance , total pulmonary resistance , left ventricular stroke work .
|
process_includes_biological_process
|
{
"id": "C0005775",
"name": "circulatory",
"pos": [
31,
42
]
}
|
{
"id": "C0039155",
"name": "systolic",
"pos": [
184,
192
]
}
|
during the study the following circulatory variables were studied : mean systemic arterial pressure , mean pulmonary arterial pressure , wedge pressure , heart rate , cardiac output , systolic and diastolic left ventricular pressure , stroke volume , total systemic resistance , total pulmonary resistance , left ventricular stroke work .
|
process_includes_biological_process
|
{
"id": "C0005775",
"name": "circulatory",
"pos": [
31,
42
]
}
|
{
"id": "C0012000",
"name": "diastolic",
"pos": [
197,
206
]
}
|
the carcinogen-induced hypomethylation correlates with the increased transcriptional complexity of the nrna of treated cells , indicating the initiation of transcription at sites previously inactive .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcriptional",
"pos": [
69,
84
]
}
|
{
"id": "C1158830",
"name": "initiation",
"pos": [
142,
152
]
}
|
a majority of the 76 neurons recorded in the forebrain changed their firing rate during orienting and/or locomotion in general ( 23 neurons ) or during behavior related to only one of the specific motivational contexts : the conspecific female ( 4 neurons ) ;
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behavior",
"pos": [
152,
160
]
}
|
{
"id": "C0026605",
"name": "motivational",
"pos": [
197,
209
]
}
|
lysates of l cells infected for 4 h with vesicular stomatitis virus were inhibited in their in vitro translational activity to about the same extent as protein synthesis was inhibited in vivo in infected l cells .
|
process_includes_biological_process
|
{
"id": "C1519614",
"name": "translational",
"pos": [
101,
114
]
}
|
{
"id": "C0597295",
"name": "protein synthesis",
"pos": [
152,
169
]
}
|
when patients hyperventilated at rest with tidal volumes , breathing frequencies , and end-tidal co2 tensions similar to those during exercise conditions , bronchodilatation also occurred , and the increase in rl following inhaled histamine during isocapnic hyperventilation was also less than at rest .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "breathing",
"pos": [
59,
68
]
}
|
{
"id": "C0004048",
"name": "inhaled",
"pos": [
223,
230
]
}
|
heart period shortening ( cardioacceleration ) began in inspiration at short breathing intervals and in expiration at long breathing intervals .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "breathing",
"pos": [
77,
86
]
}
|
{
"id": "C0231800",
"name": "expiration",
"pos": [
104,
114
]
}
|
they suggest that , at usual breathing rates , phasic respiration-related changes of vagal motoneuron activity began in expiration , progress slowly , and are incompletely expressed at fast breathing rates .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "respiration",
"pos": [
54,
65
]
}
|
{
"id": "C0231800",
"name": "expiration",
"pos": [
120,
130
]
}
|
thus , these results indicate that reproductive efficiency in gilts can be improved by intrauterine treatment with boar semen before insemination to elicit conception .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
35,
47
]
}
|
{
"id": "C0009637",
"name": "conception",
"pos": [
156,
166
]
}
|
( 1 ) transcription of the gene can occur from either of two promoters . lambda cii protein activates transcription initiation near int at pi .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
6,
19
]
}
|
{
"id": "C1158830",
"name": "transcription initiation",
"pos": [
102,
126
]
}
|
this training was accomplished simply by breathing against inspiratory resistors for 15 minutes twice a day .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "breathing",
"pos": [
41,
50
]
}
|
{
"id": "C0004048",
"name": "inspiratory",
"pos": [
59,
70
]
}
|
even in cases where it may seem superfluous , as in azoospermia , it can be used to reveal the presence of immature reproductive cells indicating retarded maturation .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
116,
128
]
}
|
{
"id": "C0678723",
"name": "maturation",
"pos": [
155,
165
]
}
|
evidence is presented suggesting that the impaired expression of the trnahis gene is not caused by inefficient transcription , but rather by defective processing of the primary transcript .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "expression",
"pos": [
51,
61
]
}
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
111,
124
]
}
|
neoplastic transformation by a cloned human cytomegalovirus dna fragment uniquely homologous to one of the transforming regions of herpes simplex virus type 2 .
|
process_includes_biological_process
|
{
"id": "C0007621",
"name": "neoplastic transformation",
"pos": [
0,
25
]
}
|
{
"id": "C1510411",
"name": "transforming",
"pos": [
107,
119
]
}
|
there was not only the therapist trying to change behavior , thinking , and feeling of the patient by cognitive techniques .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behavior",
"pos": [
50,
58
]
}
|
{
"id": "C0039869",
"name": "thinking",
"pos": [
61,
69
]
}
|
thus , the increase in the rate of synthesis of uracil nucleotides may be interpreted as an adaptative change of nucleotide metabolism in response to an increased requirement of precursors for rna synthesis .
|
process_includes_biological_process
|
{
"id": "C0597108",
"name": "nucleotide metabolism",
"pos": [
113,
134
]
}
|
{
"id": "C1328948",
"name": "rna synthesis",
"pos": [
193,
206
]
}
|
thus , hemin induction of globin gene expression in k562 cells is at the level of transcription .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene expression",
"pos": [
33,
48
]
}
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
82,
95
]
}
|
the rs on these nine farms increased from thirty-six to fifty-four , which was mainly due to the reduction of the number of inseminations required for each conception ( from 2.1 to 1.7 ) .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "rs",
"pos": [
4,
6
]
}
|
{
"id": "C0009637",
"name": "conception",
"pos": [
156,
166
]
}
|
to assess possible maternal hepatic and reproductive effects of this uncharged , low molecular weight , lipophilic chlorinated benzene 0 , 100 , 300 and 1000 mg/kg/day of 1,2,3,4-tetrachlorobenzene ( tcb ) was orally administered to pregnant rats on days 9-13 of gestation and the animals were killed on day 14 of pregnancy .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
40,
52
]
}
|
{
"id": "C0032961",
"name": "pregnancy",
"pos": [
314,
323
]
}
|
dynamics of the mitotic cycle of the kepv cells being on different interphase stages at the start of a 20 hour 2-mercaptoethanol ( 0.001 m ) treatment has been studied during the treatment and for 11 hours after washing out the agent .
|
process_includes_biological_process
|
{
"id": "C1155839",
"name": "mitotic cycle",
"pos": [
16,
29
]
}
|
{
"id": "C0021798",
"name": "interphase",
"pos": [
67,
77
]
}
|
frequent reproductive casualties ( spontaneous abortions , stillbirths , prematurity and low birth weight , congenital malformations ) were recorded in a group of 264 women who had viral hepatitis ( vh ) during pregnancy .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
9,
21
]
}
|
{
"id": "C0032961",
"name": "pregnancy",
"pos": [
211,
220
]
}
|
these studies reveal the functional characterization of four genes , the products of which are necessary for the efficient expression of the `` '' early '' '' rna transcribed segments , autonomous dna replication , and the production of normal levels of `` '' late '' '' ( 17-1-13-att'80 ) rna synthesis .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "expression",
"pos": [
123,
133
]
}
|
{
"id": "C1328948",
"name": "rna synth",
"pos": [
290,
299
]
}
|
in certain cases such a participation has also been proved : in the reproductive tract , prostaglandins are known to be involved in such events as pregnancy , parturition , dysmenorrhea and luteolysis .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
68,
80
]
}
|
{
"id": "C0032961",
"name": "pregnancy",
"pos": [
147,
156
]
}
|
to assess the impact of maternal malnutrition imposed at various stages of the reproductive cycle on pup growth and nutritional status , rats were fed 50 % of the intake of control animals fed ad libitum either before pregnancy ( r-b ) , before and during pregnancy ( r-bp ) , during lactation ( r-l ) , or throughout the experimental period ( r-bpl ) .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
79,
91
]
}
|
{
"id": "C0032961",
"name": "pregnancy",
"pos": [
256,
265
]
}
|
the effect of phenobarbital on the transcriptional activity of liver was studied by measuring the synthesis of rna by suspensions of hepatocytes isolated from rats treated with phenobarbital for various time periods .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcriptional",
"pos": [
35,
50
]
}
|
{
"id": "C1328948",
"name": "synthesis",
"pos": [
98,
107
]
}
|
this suggests that in the fast to slow transformation gene expression is regulated at the level of transcription .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene expression",
"pos": [
54,
69
]
}
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
99,
112
]
}
|
since erythroid cell nuclei have large amounts of heterochromatin and may be relatively inactive genetically , the translational control of ferritin by iron observed in red cells was studied in other tissue by isolating poly ( a+ ) rna from tadpole liver and analyzing protein synthesis in vitro .
|
process_includes_biological_process
|
{
"id": "C1519614",
"name": "translational",
"pos": [
115,
128
]
}
|
{
"id": "C0597295",
"name": "protein synthesis",
"pos": [
269,
286
]
}
|
mutations of the beta subunit of rna polymerase alter both transcription pausing and transcription termination in the trp operon leader region in vitro .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
59,
72
]
}
|
{
"id": "C0597600",
"name": "transcription termination",
"pos": [
85,
110
]
}
|
these mutant polymerases were used to investigate transcription pausing at the trp leader pause site and transcription termination at the trp attenuator .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
50,
63
]
}
|
{
"id": "C0597600",
"name": "transcription termination",
"pos": [
105,
130
]
}
|
rna polymerase isolated from a mutant which displays high transcriptional read-through of the trp operon in vivo allows greater transcriptional read-through in vitro , while rna polymerase prepared from a mutant which has reduced read-through in vivo exhibits greater termination of transcription in vitro .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcriptional",
"pos": [
58,
73
]
}
|
{
"id": "C0597600",
"name": "termination",
"pos": [
268,
279
]
}
|
the start point of transcription was determined by s1 mapping and primer extension and the site of polyadenylation by comparison with the mrna sequence determined from a cdna clone .
|
process_includes_biological_process
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
19,
32
]
}
|
{
"id": "C0949765",
"name": "polyadenylation",
"pos": [
99,
114
]
}
|
possession of this skill allows the practicing dietitian to point out clients ' discrepant behaviors or thought patterns which obstruct progression toward goals .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behaviors",
"pos": [
91,
100
]
}
|
{
"id": "C0039869",
"name": "thought",
"pos": [
104,
111
]
}
|
reproductive and maternal performance of a line of mice selected for large first parity litter size ( l+ ) and a control line ( k ) were compared under two mating systems : ( 1 ) postpartum mating ( pp ) , in which females undergo concurrent gestation and lactation , and ( 2 ) postweaning mating ( pw ) , in which females wean their litter before being remated .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
0,
12
]
}
|
{
"id": "C0032961",
"name": "gestation",
"pos": [
242,
251
]
}
|
we have utilized a recombinant vector system designed to study gene control elements by fusing them to the escherichia coli galactokinase gene ( galk ) to examine the effects of gene expression that result from introducing changes into the 5 ' noncoding leader region of the galk transcription unit .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene expression",
"pos": [
178,
193
]
}
|
{
"id": "C0040649",
"name": "galk transcription",
"pos": [
275,
293
]
}
|
we varied the length of the 5 ' leader region and found no effect on galk expression , provided that the galk initiation codon remained the first aug in the transcription unit .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "galk expression",
"pos": [
69,
84
]
}
|
{
"id": "C0040649",
"name": "transcription",
"pos": [
157,
170
]
}
|
we shall suggest a clear psychotherapeutic purpose -- that it be a place where staff members provide patients with the opportunity to become aware of fixed , stereotypical meanings that they , the patients , collectively give to the behavior , motives , and attitudes of other people .
|
process_includes_biological_process
|
{
"id": "C0004927",
"name": "behavior",
"pos": [
233,
241
]
}
|
{
"id": "C0026605",
"name": "motives",
"pos": [
244,
251
]
}
|
this study evaluates the afferent activity in the superior laryngeal nerve ( sln ) during breathing as well as during occluded inspiratory efforts .
|
process_includes_biological_process
|
{
"id": "C0035203",
"name": "breathing",
"pos": [
90,
99
]
}
|
{
"id": "C0004048",
"name": "inspiratory",
"pos": [
127,
138
]
}
|
the host cell defenses apparently can not penetrate the dense network of platelet and fibrin in the vegetation , and humoral immunity ( antibodies and complement ) are of no help against gram-positive cocci .
|
process_includes_biological_process
|
{
"id": "C0520990",
"name": "host",
"pos": [
4,
8
]
}
|
{
"id": "C0020967",
"name": "humoral immunity",
"pos": [
117,
133
]
}
|
immune response to different tick-borne encephalitis vaccines as revealed by lymphocyte blast transformation and virus neutralization tests .
|
process_includes_biological_process
|
{
"id": "C0301872",
"name": "immune response",
"pos": [
0,
15
]
}
|
{
"id": "C0024262",
"name": "lymphocyte",
"pos": [
77,
87
]
}
|
reproductive parameters measured included conception , litter size , pup birth weight , number stillborn , survival to weaning , and weaning weight .
|
process_includes_biological_process
|
{
"id": "C0035150",
"name": "reproductive",
"pos": [
0,
12
]
}
|
{
"id": "C0009637",
"name": "conception",
"pos": [
42,
52
]
}
|
we therefore suggest that dna sequences which regulate beta-globin gene expression during mel differentiation are located both 5 ' and 3 ' to the translation initiation site .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene expression",
"pos": [
67,
82
]
}
|
{
"id": "C1519613",
"name": "translation initiation",
"pos": [
146,
168
]
}
|
these results suggest that immune complexes may interfere with antibody mediated immunity to p. berghei and may also retard development of the induced immune response .
|
process_includes_biological_process
|
{
"id": "C0020964",
"name": "immunity",
"pos": [
81,
89
]
}
|
{
"id": "C0301872",
"name": "immune response",
"pos": [
151,
166
]
}
|
parameter studies of mitotic cycles of the lymphoid population in the rats respiratory system showed that after gamma-globulin injection to the respiratory system the main mechanism of cellular division consists of synchronized entry of cells to the mitotic cycle , shortening of the parameters and time of cellular regeneration .
|
process_includes_biological_process
|
{
"id": "C0007590",
"name": "cellular division",
"pos": [
185,
202
]
}
|
{
"id": "C0026255",
"name": "mitotic cycle",
"pos": [
250,
263
]
}
|
it may be concluded that t3 presents an early effect on gene expression , involving changes either at the gene level or and at some post transcriptional level .
|
process_includes_biological_process
|
{
"id": "C0017262",
"name": "gene expression",
"pos": [
56,
71
]
}
|
{
"id": "C0040649",
"name": "transcriptional",
"pos": [
137,
152
]
}
|
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