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Identification of large offspring syndrome during pregnancy through ultrasonography and maternal blood transcriptome analyses
developmental biology
String-Pulling as a Behavioral Assessment of Skilled Forelimb Motor Function in a Middle Cerebral Artery Occlusion Rat Model
animal behavior and cognition
Quantitative crosslinking and mass spectrometry determine binding interfaces and affinities mediating kinetochore stabilization
biochemistry
Imaging optically thick tissues simply and reproducibly: a practical guide to Lightsheet Macroscopy
bioengineering
Full-mouth photoacoustic/ultrasound imaging of the periodontal pocket with a compact intraoral transducer
bioengineering
StORF-Reporter: Finding Genes between Genes
bioinformatics
ShrinkCRISPR : A flexible method for differential fitness analysis of CRISPR-Cas9 screen data.
bioinformatics
Phasor-Based Multi-Harmonic Unmixing for in-vivo Hyperspectral Imaging
biophysics
RNA helicase DDX5 mediates adaptive response to multi-kinase inhibitors in liver cancer
cancer biology
Shedding Light on the Black Box of a Neural Network Used to Detect Prostate Cancer in Whole Slide Images by Occlusion-Based Explainability
pathology
An untargeted metabolomics analysis of exogenous chemicals in human milk and transfer to the infant
pharmacology and toxicology
Mass red blood cell extravasation and tubular uptake results in toxic injury to the tubules during kidney ischemia from venous clamping
physiology
Influence of ambient day light variations and age on the Iris-pupillary area ratio in beef cattle
physiology
Effect of tempol on post-thaw semen parameters and fertility during chicken semen cryopreservation
physiology
Characterization of EDS1-independent plant defense responses against bacterial pathogens using Duckweed/Pseudomonas pathosystems
plant biology
Relative stability of mRNA and protein severely limits inference of gene networks from single-cell mRNA measurements
systems biology
Long-range inhibition synchronizes and updates prefrontal task activity
neuroscience
Impact of 98 LRRK2 variants linked to Parkinson's Disease on kinase activity and microtubule binding
neuroscience
Downregulating α-synuclein in iPSC-derived dopaminergic neurons mimics electrophysiological phenotype of the A53T mutation
neuroscience
A neural decision signal during internal sampling from working memory
neuroscience
Munc13 supports vesicle fusogenicity after disrupting active zone scaffolds and synaptic vesicle docking
neuroscience
Spatially resolved transcriptomics reveals innervation-responsive functional clusters in skeletal muscle
molecular biology
Temporal and Spatial Resolution of a Protein Quake that Activates Hydrogen Tunneling in Soybean Lipoxygenase
biophysics
Multi-environment genome-wide association mapping of culm morphology traits in barley
plant biology
Active Anemosensing Hypothesis: How Flying Insects Could Estimate Ambient Wind Direction Through Sensory Integration & Active Movement
animal behavior and cognition
Targeted Proteomics and Support Vector Classification Reveal Potential Biomarkers for the Early Detection of High-grade Serous Ovarian Cancer
cancer biology
GPR183 mediates the capacity of the novel CD47-CD19 bispecific antibody TG-1801 to heighten ublituximab-umbralisib (U2) anti-lymphoma activity
cancer biology
The mouse claustrum synaptically connects cortical network motifs
neuroscience
Follicular helper T cells expressing Blimp1 are specialized for plasma cell differentiation
immunology
MAIT cells activate dendritic cells to promote T follicular helper cell differentiation and humoral immunity
immunology
Rapid and accurate identification of Escherichia coli STEC O157:H7 by mass spectrometry, artificial intelligence and detection of specific biomarkers peaks.
microbiology
Development of a long-read NGS workflow for improved characterization of fastidious respiratory mycoplasmas
microbiology
Cell type-specific Expression Quantitative Trait Loci
genomics
PanGu Drug Model: Learn a Molecule Like a Human
biochemistry
Prediction of brain functions from structural connectome using graph neural network
bioengineering
Informational Masking Can Constrain Acoustically Guided Mating Behavior
neuroscience
History of previous midlife estradiol treatment permanently alters interactions of brain insulin-like growth factor-1 signaling and hippocampal estrogen synthesis to enhance cognitive aging in a rat model of menopause
neuroscience
Hippocampal CA1 represents action and reward events instantly compared to the superficial and deep layers of the lateral entorhinal cortex
neuroscience
Different olfactory neuron classes use distinct temporal and molecular programs to complete synaptic development
neuroscience
Irrational choices via a curvilinear representational geometry for value
neuroscience
An Open and Continuously Updated Fern Tree of Life (FTOL)
evolutionary biology
Direct and indirect impacts of positive selection on genomic variation in Drosophila serrata
genetics
De novo sequencing, diploid assembly, and annotation of the black carpenter ant, Camponotus pennsylvanicus, and its symbionts by one person for $1000, using nanopore sequencing.
genomics
Drug combination prediction for cancer treatment using disease-specific drug response profiles and single-cell transcriptional signatures
bioinformatics
Size matters - the impact of nucleus size on results from spatial transcriptomics
bioinformatics
Beneficial and Detrimental Effects of Nonspecific Binding During DNA Hybridization
biophysics
Antibody evolution to SARS-CoV-2 after single-dose Ad26.COV2.S vaccine
immunology
In vivo prenylomic profiling in the brain of a transgenic mouse model of Alzheimer's disease reveals increased prenylation of a key set of proteins
biochemistry
A single vesicle fluorescence-bleaching assay for multi-parameter analysis of proteoliposomes by total internal reflection fluorescence microscopy
biochemistry
miRNA upregulate protein and glycan expression via direct activation in proliferating cells
biochemistry
Decision Tree Ensembles Utilizing Multivariate Splits Are Effective at Investigating Beta-Diversity in Medically Relevant 16S Amplicon Sequencing Data
bioinformatics
Identification and receptor mechanism of TIR-catalyzed small molecules in plant immunity
plant biology
New broad-spectrum anti-Flavivirus human antibodies with Zika virus-neutralizing potential
immunology
Recall of pre-existing cross-reactive B cell memory following Omicron breakthrough infection
immunology
Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2
immunology
Environment and the Evolutionary Trajectory of Horizontal Gene Transfer.
microbiology
Frequency of change determines effectiveness of microbial response strategies in sulfidic stream microbiomes
microbiology
Functional Biomarkers of Ex-vivo Dental Caries Onset
microbiology
Surface microbiota of Mediterranean loggerhead sea turtles unravelled by 16S and 18S amplicon sequencing
microbiology
GTP-bound E. coli FtsZ filaments are composed of Tense monomers: A DNP NMR study using interface detection.
microbiology
Feedback linking cell envelope stiffness, curvature, and synthesis enables robust rod-shaped bacterial growth
microbiology
The temporal transcriptomic signature of cartilage formation
molecular biology
Convergence of immune escape strategies highlights plasticity of SARS-CoV-2 spike
molecular biology
Evidence that Nek1 does not phosphorylate Rad54-S572 during recovery from IR
molecular biology
USP18 is an essential regulator of muscle cell differentiation and maturation
cell biology
HSD3B1 is an Oxysterol 3β-Hydroxysteroid Dehydrogenase in Human Placenta
biochemistry
Actin turnover required for adhesion-independent bleb migration
biophysics
Integrative conformational ensembles of Sic1 using different initial pools and optimization methods
biophysics
Head-to-head comparison of CCN4, DNMT3A, PTPN11, and SPARC as suppressors of anti-tumor immunity
cancer biology
Characterization of cell-fate decision landscapes by estimating transcription factor dynamics.
systems biology
Physiopathological changes of ferritin mRNA density and distribution in hippocampal astrocytes in the mouse brain
neuroscience
Fasciola hepatica Fatty Acid Binding Protein 1 modulates T cell polarization by promoting dendritic cell thrombospondin-1 secretion without affecting metabolic homeostasis in obese mice
immunology
Omicron breakthrough infection drives cross-variant neutralization and memory B cell formation
immunology
A 3' UTR-derived small RNA connecting nitrogen and carbon metabolism in enteric bacteria
microbiology
Periplasmic oxidized-protein repair during copper stress in E. coli: a focus on the metallochaperone CusF.
microbiology
Comparative metagenomic analysis of biosynthetic diversity across sponge microbiomes highlights metabolic novelty, conservation and diversification
microbiology
Single-Molecule Analysis of DNA-binding proteins from Nuclear Extracts (SMADNE)
molecular biology
Topographically distinct adaptive landscapes for skulls, skeletons, and size explain the dietary adaptive radiation of Carnivora (Mammalia)
evolutionary biology
Olfactory Sensitivity Aligns with Caste Revealing Multipotential Minors and Specialized Soldier Majors in Camponotus floridanus Ants
evolutionary biology
Efflux-linked Accelerated Evolution of Antibiotic Resistance at a Population Edge
microbiology
Bacterial threat assessment of bacteriophage infection is mediated by intracellular polyamine accumulation and Gac/Rsm signaling
microbiology
Allopeptimicins: unique antibacterial metabolites generated by hybrid PKS-NRPS, with original self-defense mechanism in Actinoallomurus
microbiology
Overexpression of the WAPO-A1 gene increases the number of spikelets per spike in bread wheat
plant biology
CryoGrid-PIXUL-RNA: High throughput RNA isolation platform for tissue transcript analysis
molecular biology
Spatial-CITE-seq: spatially resolved high-plex protein and whole transcriptome co-mapping
genomics
Late maturation of executive control promotes conceptual development
neuroscience
Explaining flexible continuous speech comprehension from individual motor rhythms
neuroscience
Inter-Individual Variability in Dorsal Stream Dynamics During Word Production
neuroscience
Robustness of the ferret model for influenza risk assessment studies: a cross-laboratory exercise
microbiology
Engineering a more specific E. coli glyoxylate/hydroxypyruvate reductase for coupled steady state kinetics assays
biochemistry
The optimal strategy of incompatible insect technique (IIT) using Wolbachia to control Malaria
pathology
Building molecular band-pass filters via molecular sequestration
synthetic biology
Modulation of C5a-C5aR1 signaling alters the dynamics of AD progression
neuroscience
Pleiotrophin signals through ALK receptor to enhance growth of neurons in the presence of inhibitory CSPGs
neuroscience
The WalRK Two-component system is Essential for Proper Cell Envelope Biogenesis in Clostridioides difficile
microbiology
Robust Variation in Infant Gut Microbiome Assembly Across a Spectrum of Lifestyles
microbiology
Novel Requirement for Staphylococcal Cell Wall-Anchored Protein SasD in Pulmonary Infection
microbiology
Activation of the integrative and conjugative element Tn916 causes growth arrest and death of host bacteria
microbiology
Extensive heterogeneity of the HIV-1 infected CD4+ T-cell reservoir revealed by single-cell viral ASAPseq
microbiology
The fluorescence-activating and absorption-shifting tag (FAST) enables live-cell fluorescence imaging of Methanococcus maripaludis
microbiology