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Moxifloxacin-mediated killing of Mycobacterium tuberculosis involves respiratory downshift, reductive stress, and ROS accumulation
|
microbiology
|
Anthropogenic disturbance impacts gut microbiome homeostasis in a Malagasy primate
|
microbiology
|
Evidence for a widespread third system for bacterial polysaccharide export across the outer membrane comprising a composite OPX/β-barrel translocon
|
microbiology
|
Re-engineering of CUP1 promoter and Cup2/Ace1 transactivator to convert Saccharomyces cerevisiae into a whole-cell eukaryotic biosensor capable of detecting 10 nM of bioavailable copper
|
molecular biology
|
Nrf2 prevents diabetic cardiomyopathy via antioxidation and normalization of glucose and lipid metabolism in the heart
|
molecular biology
|
Overactive mitochondrial DNA replisome causes neonatal heart failure via ferroptosis
|
molecular biology
|
Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis.
|
cell biology
|
Rheology of growing axons
|
developmental biology
|
Western spotted skunks provide important food web linkages in forest of the Pacific Northwest
|
ecology
|
hemispheR: an R package for fisheye canopy image analysis
|
ecology
|
Genomic legacies of ancient adaptation illuminate the GC-content evolution in bacterial genomes
|
evolutionary biology
|
Comparing evolvability and pleiotropy across environments
|
evolutionary biology
|
Mechanism-based crosslinking probes capture E. coli ketosynthase FabB in conformationally-distinct catalytic states.
|
biochemistry
|
Nuclease proteins CifA and CifB promote spermatid DNA damage associated with symbiont-induced cytoplasmic incompatibility
|
biochemistry
|
Structural and Preliminary Biochemical Characterization of MppQ, a PLP-Dependent Aminotransferase from Streptomyces hygroscopicus
|
biochemistry
|
Engineering functional membrane-membrane interface by InterSpy
|
synthetic biology
|
Screening candidate genes related to psoas muscle traits in Debao and Landrace pigs based on transcriptome analysis
|
genomics
|
Lumbar time-varying muscle synergies in trunk flexion and bending movements at different velocities
|
bioengineering
|
MAECI: A Pipeline For Generating Consensus Sequence With Nanopore Sequencing Long-read Assembly and Error Correction
|
bioinformatics
|
Collagen remodeling dictates pancreatic cancer bioenergetics and outcome through DDR1 activation or degradation
|
cancer biology
|
Biological responses to terahertz radiation with different power density in primary hippocampal neurons
|
neuroscience
|
Sub-type selective muscarinic acetylcholine receptor modulation for the treatment of parkinsonian tremor
|
neuroscience
|
Molecular differences in APOBEC3 counteraction by primate herpesviruses reveal an evolutionary link between the genesis of APOBEC3B and novel viral ribonucleotide reductase function
|
microbiology
|
Surface detection of SARS-CoV-2 by lateral flow LAMP
|
genetics
|
Melanoma cells release DEL-1 via small extracellular vesicles
|
cancer biology
|
Gut Enterochromaffin Cells are Critical Drivers of Visceral Pain and Anxiety
|
physiology
|
Cholinergic stimulation modulates the functional composition of CA3 cell types in the hippocampus
|
neuroscience
|
Transcriptional Heterogeneity and Cell Cycle Regulation as Central Determinants of Primitive Endoderm Priming.
|
developmental biology
|
The angular gyrus is engaged by autobiographical recall not object-semantics, or event-semantics: Evidence from contrastive propositional speech production
|
neuroscience
|
Molecular dissection of condensin II-mediated chromosome assembly using in vitro assays
|
cell biology
|
Chromatin regulates genome-wide transcription factor binding affinities
|
genomics
|
Socially learned arbitrary call use in a wild primate
|
animal behavior and cognition
|
One-trial social learning of vervet monkey alarm calling
|
animal behavior and cognition
|
Genetically encoded sensors for analysing neurotransmission among synaptically-connected neurons
|
neuroscience
|
Emergence of distinct neural subspaces in motor cortical dynamics during volitional adjustments of ongoing locomotion
|
neuroscience
|
Human statistical learning dynamically shapes the hippocampal processing of temporal associations
|
neuroscience
|
A deep hierarchy of predictions enables assignment of semantic roles in real-time speech comprehension
|
neuroscience
|
Comprehensive Structural Variant Detection: From Mosaic to Population-Level
|
bioinformatics
|
Immediate predation risk alters the relationship between potential and realised selection on male traits in the Trinidad guppy Poecilia reticulata
|
evolutionary biology
|
A playback paradox? Nathusius' bats, Pipistrellus nathusii, bypass mating and fueling opportunities on migratory transit flights
|
animal behavior and cognition
|
Species-typical chemical signals mediate reproductive isolation in a teleost fish
|
animal behavior and cognition
|
GoFish: A low-cost, open-source platform for closed-loop behavioural experiments on fish
|
animal behavior and cognition
|
Delayed dynamics of migratory response to CTLA-4 blockade reveals a mechanistic view on potential T cells reinvigoration following immune checkpoint blockade
|
cancer biology
|
In Utero Activation of NK Cells in Congenital CMV Infection
|
immunology
|
Decision heuristics in contexts exploiting intrinsic skill
|
neuroscience
|
Bmal1-knockout mice exhibit reduced cocaine-seeking behaviour and cognitive impairments
|
neuroscience
|
Factors determining distributions of rainforest Drosophila shift from interspecific competition to high temperature with decreasing elevation
|
ecology
|
Newfoundland and Labrador: A mosaic founder population of an Irish and British diaspora from 300 years ago.
|
genetics
|
Estimates of in vivo turnover numbers by simultaneously considering data from multiple conditions improve metabolic predictions
|
bioinformatics
|
Reproducible stool metagenomic biomarkers linked to the melanoma immunotherapy positive outcome
|
bioinformatics
|
Age at cancer diagnosis by breed, weight, sex, and cancer type in a cohort of over 3,000 dogs: determining the optimal age to initiate cancer screening in canine patients
|
cancer biology
|
Functional autapses form in striatal parvalbumin interneurons but not medium spiny neurons
|
neuroscience
|
Trait anxiety is associated with hidden state inference during aversive reversal learning
|
neuroscience
|
Visuo-tactile integration in texture perception: A replication and extension study
|
neuroscience
|
Cellular and Molecular Organization of the Rhesus Macaque Dorsal Horn with a Comparison to Mouse
|
neuroscience
|
Nonlinear Parameter and State Estimation Approach in End-stage Kidney Disease Patients
|
bioengineering
|
Factors regulating translation coupled mRNA degradation in yeast
|
bioinformatics
|
GenMPI: Cluster Scalable Variant Calling forShort/Long Reads Sequencing Data
|
bioinformatics
|
LENS - Landscape of Effective Neoantigens Software
|
cancer biology
|
Tackling polypharmacology of kinase inhibitors by transcription factor activity profiling.
|
pharmacology and toxicology
|
Speed-dependent biomechanical changes vary across individual gait metrics post-stroke relative to neurotypical adults
|
neuroscience
|
Cue-driven motor planning facilitates express visuomotor responses in human arm muscles
|
neuroscience
|
An open-source, ready-to-use and validated ripple detector plugin for the Open Ephys GUI
|
neuroscience
|
Functional Cell Types in the Mouse Superior Colliculus
|
neuroscience
|
Microstructural alterations in tract development in college football: a longitudinal diffusion MRI study
|
neuroscience
|
Separation of NaV Subtypes in the Axon InitialSegment can Impede or Promote Backpropagation
|
neuroscience
|
Brain-heart interactions are optimized across the respiratory cycle via interoceptive attention
|
neuroscience
|
Stochastic analysis of frequency bandwidth and noise attenuation in neurotransmission
|
neuroscience
|
Persistent pervasive transcription in RNA exosome depleted oocytes results in loss of female fertility
|
developmental biology
|
Bird community structure in a mixed forest-production landscape in the northern Western Ghats, India
|
ecology
|
Evolutionary responses of a reef-building coral to climate change at the end of the last glacial maximum
|
evolutionary biology
|
Behavioral dysregulation and monoaminergic deficits precede memory impairments in human tau-overexpressing (htau) mice
|
animal behavior and cognition
|
Lumbar time-varying muscle synergies in trunk flexion and bending movements at different velocities
|
bioengineering
|
Machine Learning Classification Reveals Robust Morphometric Biomarker of Glial and Neuronal Arbors
|
bioengineering
|
A computational modeling of primary-microRNA expression
|
bioinformatics
|
Cellpose 2.0: how to train your own model
|
bioinformatics
|
Motifizer: a tool for parsing high-throughput sequencing datasets and quantitative comparative analyses of transcription factor-binding sites
|
bioinformatics
|
Single-cell multimodal modeling with deep parametric inference
|
bioinformatics
|
epiAneufinder: identifying copy number variations from single-cell ATAC-seq data
|
bioinformatics
|
Communication-Efficient Cluster Scalable Genomics Data Processing Using Apache Arrow Flight
|
bioinformatics
|
Elongated exons encoding disordered regions expedited eukaryotic evolution
|
bioinformatics
|
A multiscale whole-cell theory for mechano-sensitive migration on viscoelastic substrates
|
biophysics
|
Drug addiction mutations unveil a methylation ceiling in EZH2-mutant lymphoma
|
cancer biology
|
A paracrine circuit of IL-1b/IL-1R1 between myeloid and tumor cells drives glioblastoma progression
|
cancer biology
|
Laboratory evolution of synthetic electron transport system variants reveals a larger metabolic respiratory system and its plasticity
|
systems biology
|
Chronic hM3Dq-DREADD mediated chemogenetic activation of parvalbumin-positive inhibitory interneurons in postnatal life alters anxiety and despair-like behavior in adulthood in a task and sex-dependent manner
|
neuroscience
|
The Insulin receptor regulates the persistence of mechanical nociceptive sensitization in flies and mice
|
neuroscience
|
Bidirectional modulation of neuronal excitability via ionic actuation of potassium
|
neuroscience
|
The influence of stereopsis on visual saliency in a proto-object based model of selective attention
|
neuroscience
|
Information theory characteristics improve the prediction of lithium response in bipolar disorder patients using an SVM classifier
|
neuroscience
|
DomeVR: A setup for experimental control of an immersive dome virtual environment created with Unreal Engine 4
|
neuroscience
|
Functional coupling of the mesencephalic locomotor region and V2a reticulospinal neurons driving forward locomotion
|
neuroscience
|
Firing behavior of single motor neurons of the tibialis anterior in human walking as non-invasively revealed by HDsEMG decomposition
|
neuroscience
|
Kidins220 regulates the development of B cells bearing the {lambda} light chain
|
immunology
|
Breast cancer stem cell-derived tumors escape from γδ T cell immunosurveillance in vivo by modulating γδ T cell ligands
|
immunology
|
T cell-mediated development of stromal fibroblasts with an immune-enhancing chemokine profile
|
immunology
|
Climate change will redefine taxonomic, functional, and phylogenetic diversity patterns of Odonata in space and time
|
ecology
|
Prey resources are more important than climatic conditions for predicting the distribution of a broad-ranged apex predator
|
ecology
|
Systematic identification of unannotated ORFs in Drosophila reveals evolutionary heterogeneity
|
evolutionary biology
|
The genetic architectures of vine and skin maturity in tetraploid potato
|
genetics
|
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