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Advanced transcriptomic analysis reveals the role of efflux pumps and media composition in antibiotic responses of Pseudomonas aeruginosa
|
systems biology
|
An Ultralong Bovine CDRH3 that Targets a Conserved, Cryptic Epitope on SARS-CoV and SARS-CoV-2
|
molecular biology
|
Impact of energy limitations on function and resilience in long-wavelength Photosystem II
|
biochemistry
|
Phosphorylation of SAMHD1 Thr592 increases C-terminal domain dynamics, tetramer dissociation, and ssDNA binding kinetics
|
biochemistry
|
Deep Local Analysis evaluates protein docking conformations with locally oriented cubes
|
bioinformatics
|
Architecture of the chikungunya virus replication organelle
|
biophysics
|
Copper binding leads to increased dynamics in the regulatory N-terminal domain of full-length human copper transporter ATP7B
|
biophysics
|
Overexpression of TopBP1 leads to transformation with a TP53 mutation of non-tumorigenic breast epithelial cells
|
cancer biology
|
Nitroimidazopyrazinones with oral activity against tuberculosis and Chagas disease in mouse models of infection
|
pharmacology and toxicology
|
PEP7 is a ligand for receptor kinase SIRK1 to regulate aquaporins and root growth
|
plant biology
|
The potyviral protein 6K2 from Turnip mosaic virus increases plant resilience to drought
|
plant biology
|
Screening of the optimal CpG-oligodeoxynucleotide for anti-inflammatory responses in avian macrophage cell line HD11
|
immunology
|
Evidence for complex interplay between quorum sensing and antibiotic resistance in Pseudomonas aeruginosa
|
microbiology
|
Extended genomic analyses of the broad-host-range phages vB_KmiM-2Di and vB_KmiM-4Dii reveal slopekviruses have highly conserved genomes
|
microbiology
|
A positive feedback loop controls Toxoplasma chronic differentiation
|
microbiology
|
Dental pulp metagenomics reveals ancient human Herpesviridae.
|
microbiology
|
Culexarchaeia, a novel archaeal class of anaerobic generalists inhabiting geothermal environments
|
microbiology
|
Using Culture-Enriched Phenotypic Metagenomics for Targeted High-Throughput Monitoring of Clinically-Important Fraction of Beta-Lactam Resistome
|
microbiology
|
Unexpected Complexity of the Ammonia Monooxygenase in Archaea
|
microbiology
|
Barcoding genetically distinct Plasmodium falciparum strains for comparative assessment of fitness and antimalarial drug resistance
|
microbiology
|
Disentangling leaf-microbiome interactions in Arabidopsis thaliana by network mapping
|
microbiology
|
Structural studies of hepatitis C virus non-structural protein-5b of genotype 4a
|
molecular biology
|
New system for serial crystallography data collection at SBC APS
|
molecular biology
|
Multiple congenital malformations arise from somatic mosaicism for constitutively active Pik3ca signalling
|
developmental biology
|
Overlapping and distinct cis-acting requirements for oskar mRNA localization pathways
|
developmental biology
|
The {varphi}PA3 Phage Nucleus is Enclosed by a Self-Assembling, 2D Crystalline Lattice
|
biochemistry
|
Oncogenic mutations of PIK3CA lead to increased membrane recruitment driven by reorientation of the ABD, p85 and C-terminus
|
biochemistry
|
Cryo-EM structure of the diapause chaperone artemin
|
biochemistry
|
Structure Of Eukaryotic Type III Glutamine Synthetase Lacking Ring-Ring Quaternary Contacts
|
biochemistry
|
Single-molecule tracking of Nodal and Lefty in live zebrafish embryos supports hindered diffusion model
|
biophysics
|
Genome-wide fitness analysis identifies genes required for in vitro growth and macrophage infection by African and Global Epidemic pathovariants of Salmonella Enteritidis
|
microbiology
|
Bps polysaccharide of Bordetella pertussis resists antimicrobial peptides by functioning as a dual surface shield and decoy and converts Escherichia coli into a respiratory pathogen.
|
microbiology
|
A multidrug-resistant Salmonella enterica serotype Typhimurium DT104 lineage circulating among humans and cattle in the United States lost the ability to produce pertussis-like toxin ArtAB in close temporal proximity to the global DT104 epidemic
|
microbiology
|
Listeria monocytogenes Co-opts Caveolin-Mediated E-cadherin Trafficking and Macropinocytosis for Epithelial Cell-to-Cell Spread
|
microbiology
|
Extracellular Vesicles from PRPF31+/- iPSC-Derived RPE Have a Distinct RNA Profile Compared to Those From Healthy RPE
|
molecular biology
|
Sequential addition of neuronal stem cell temporal cohorts generates a feed-forward circuit in the Drosophila larval nerve cord
|
developmental biology
|
Multiplexed promoter and gene editing in wheat using the virus-based guide RNA delivery system
|
genetics
|
Understanding the Spin Crossover Dynamical Effects of the Dioxygen Binding and Activation on HOD enzyme
|
biochemistry
|
Cell-free mutant analysis combined with structure prediction of a lasso peptide biosynthetic protein B2
|
biochemistry
|
Laboratory-acquired mutations fall outside the wild-type alleleome of Escherichia coli
|
bioengineering
|
Impact of temperature and time on DNA-free Cas9-ribonucleoprotein mediated gene editing in wheat protoplasts and immature embryos
|
plant biology
|
Organizing laboratory information to analyze the reproducibility of experimental workflows
|
synthetic biology
|
The purified recombinant FAT domain of the Focal Adhesion Kinase does not bind directly to recombinant Talin or MBD2 in vitro
|
biophysics
|
Host range expansion of Shigella phage Sf6 evolves through the dual roles of its tailspike
|
microbiology
|
Microaerobic conditions and the complex regulation of natural competence in Staphylococcus aureus
|
microbiology
|
KSHV Topologically Associating Domains in Latent and Reactivated Viral Chromatin
|
microbiology
|
The cytolethal distending toxin modulates cell differentiation and elicits epithelial to mesenchymal transition
|
microbiology
|
Transformation of the symbiotic alga Oophila amblystomatis : a new toolbox for animal-algae symbiosis studies.
|
molecular biology
|
Bi-phasic regulation of AIMP2 and its splice variant in PARP-1- dependent neurodegeneration
|
molecular biology
|
Agricultural margins could enhance landscape connectivity for pollinating insects across the Central Valley of California, U.S.A.
|
ecology
|
Evidence of attack deflection suggests adaptive evolution of wing tails in butterflies
|
evolutionary biology
|
The intergenerational transmission of educational attainment: A closer look at the (interrelated) roles of paternal involvement and genetic inheritance
|
genetics
|
Novel Bruton's Tyrosine Kinase (BTK) substrates for time-resolved luminescence assays
|
biochemistry
|
Cryo-EM reveals a mechanism of USP1 inhibition through a cryptic binding site
|
biochemistry
|
Cardiac hemodynamics and ventricular stiffness of sea-run cherry salmon (Oncorhynchus masou masou) differ critically from those of landlocked masu salmon
|
physiology
|
Signalling speed along a key white matter tract influences memory recall ability in humans
|
neuroscience
|
A visual representation of the hand in the resting somatomotor regions of the human brain
|
neuroscience
|
Auditory Language Comprehension During Saccadic Eye Movements: An Investigation Using the N400 Event-Related Brain Potential
|
neuroscience
|
Unexpected inhibition of motor function by dopamine activation of D1/D2 co-expressing striatal neurons.
|
neuroscience
|
Transcriptional targets of senataxin and E2 promoter binding factors are associated with neuro-degenerative pathways during increased autophagic flux
|
genomics
|
Mouse mutants in schizophrenia risk genes GRIN2A and AKAP11 show EEG abnormalities in common with schizophrenia patients
|
neuroscience
|
Probing different paradigms of morphine withdrawal on sleep behavior in male and female C57BL/6J mice
|
neuroscience
|
HOTARU: Automatic sorting system for large scale calcium imaging data
|
neuroscience
|
Mind the gap: Nodes of Ranvier are remodeled by chronic psychosocial stress and neuronal activity
|
neuroscience
|
Goal-directed recruitment of Pavlovian biases through selective visual attention
|
neuroscience
|
Population modeling with machine learning can enhance measures of mental health - Open-Data Replication
|
neuroscience
|
Reactivating ordinal position information from auditory sequence memory in human brains
|
neuroscience
|
The theta paradox: 4-8 Hz EEG oscillations reflect both local sleep and cognitive control
|
neuroscience
|
The strength of feedback processing is associated with resistance to visual backward masking during illusory contour processing in adult humans.
|
neuroscience
|
Analysis of non-human primate models for evaluating prion disease therapeutic efficacy
|
neuroscience
|
Invasion of malaria mosquitoes natural population by parasitic nematodes Dirofilaria along Ob River basin in Western Siberia
|
ecology
|
Lichen speciation is sparked by a substrate requirement shift and reproduction mode differentiation
|
evolutionary biology
|
The evolutionary demise of a social interaction: social partners differ in the rate at which interacting phenotypes are lost
|
evolutionary biology
|
A Genome-Wide Association Analysis of Happiness: Consistent Genetic Effects Across the Lifespan and Across Genetic Ancestries in Multiple Cohorts.
|
genetics
|
Doctoring Direct-to-Consumer Genetic Tests with DNA Spike-Ins
|
genetics
|
Potential impact of TE-derived sRNA on gene regulation in the grassBrachypodium distachyon
|
genomics
|
Genomic characteristics, virulence and antimicrobial resistance in avian pathogenic Escherichia coli MTR_BAU02 strain isolated from layer farms in Bangladesh
|
genomics
|
Genomic signatures of selection associated with benzimidazole drug treatments in Haemonchus contortus field populations
|
genomics
|
Asynchrony rescues statistically-optimal group decisions from information cascades through emergent leaders
|
animal behavior and cognition
|
Can the Insect Path Integration Memory be a Bump Attractor?
|
animal behavior and cognition
|
QuasiFlow: a bioinformatic tool for genetic variability analysis from next generation sequencing data
|
bioinformatics
|
Extracting multiple surfaces from 3D microscopy images in complex biological tissues with the Zellige software tool.
|
bioinformatics
|
SimSearch: A Human-in-the-Loop Learning Framework for Fast Detection of Regions of Interest in Microscopy Images
|
bioinformatics
|
Direct evidence for pinning of single, ice-bound antifreeze proteins by subzero nanoscopy
|
biophysics
|
Hyperglycemia and Cancer. Human lung carcinoma by means of Raman spectroscopy and imaging
|
cancer biology
|
Nucleation complex behaviour is critical for cortical microtubule array homogeneity and patterning
|
plant biology
|
Canonical Strigolactones Are Not the Tillering-Inhibitory Hormone but Rhizospheric Signals in Rice
|
plant biology
|
The pitfalls of measuring representational similarityusing representational similarity analysis
|
neuroscience
|
MicroRNA inhibition using antimiRs in acute human brain tissue sections
|
neuroscience
|
Effects of experiencing CS-US pairings on instructed fear reversal
|
neuroscience
|
Concentration dependent dual effect of the endozepine ODN on neuronal spiking activity
|
neuroscience
|
Blood oxygenation-level dependent cerebrovascular reactivity imaging as strategy to monitor CSF-hemoglobin toxicity
|
neuroscience
|
Single-neuron bursts encode pathological oscillations in Parkinson's disease and essential tremor
|
neuroscience
|
Attentional rhythms are generated in binocular cells
|
neuroscience
|
Developmental switch in prediction and adaptation to pain in human neonates
|
neuroscience
|
Comparative study between radiofrequency- and muscimol-induced inhibition of cultured networks of cortical neuron
|
neuroscience
|
Zebrafish Galectin 3 binding protein (Lgals3bp) is the target antigen of the microglial 4C4 monoclonal antibody
|
immunology
|
Kidins220 promotes thymic iNKT cell development by reducing TCR signals, but enhances TCR signals in splenic iNKT cells
|
immunology
|
Fragmented habitat compensates for the adverse effects of genetic bottleneck
|
evolutionary biology
|
The net-like heterotrophic amoeba Leukarachnion salinum sp. nov. (Ochrophyta, Stramenopiles) has a cryptic plastid
|
evolutionary biology
|
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