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Remodeling of gene regulatory networks underlying thermogenic stimuli-induced adipose beiging
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genomics
|
A Self-Purifying Microfluidic System for Identifying Drugs Acting Against Adult Schistosomes
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bioengineering
|
Engineering Proprioceptive Implants via Surgical and Regenerative Approaches: Preliminary Interpretations
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bioengineering
|
Noncoding RNA's competing endogenous gene pair as motif in serous ovarian cancer
|
bioinformatics
|
Principal component analysis- and tensor decomposition-based unsupervised feature extraction to select more reasonable differentially methylated cytosines: Optimization of standard deviation versus state-of-the-art methods
|
bioinformatics
|
DeepToA: An Ensemble Deep-Learning Approach to Predicting the Theater of Activity of a Microbiome
|
bioinformatics
|
Talin-drug interaction reveals a key molecular determinant for biphasic mechanical effect: studied under single-molecule resolution
|
biophysics
|
Tumor spheroids accelerate persistently invading cancer cells
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biophysics
|
Loss of HOXA10 causes endometrial hyperplasia progressing to endometrial cancer
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cancer biology
|
The catalytic domain of cellulose synthase (CESA) is involved in vesicle trafficking and protein dynamics
|
plant biology
|
Sloppiness: fundamental study, new formalism and quantification
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systems biology
|
Nuclear inhibitor of protein phosphatase 1 (NIPP1) regulates CNS tau phosphorylation and myelination during development
|
neuroscience
|
Perivascular SPP1 Mediates Microglial Engulfment of Synapses in Alzheimers Disease Models
|
neuroscience
|
Effect of LSD and music on the time-varying brain dynamics
|
neuroscience
|
Delay-related activity in marmoset prefrontal cortex
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neuroscience
|
Dichotomic Regulation of Striatal Plasticity by Dynorphin
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neuroscience
|
Overactivation of a sleep-active neuron decouples survival from the need to sleep
|
neuroscience
|
All-optical visualization of specific molecules in the ultrastructural context of brain tissue
|
neuroscience
|
Neuronal nuclear calcium signaling suppression of microglial reactivity is mediated by osteoprotegerin after traumatic brain injury
|
neuroscience
|
Single-cell transcriptomics reveal hyperacute cytokine and immune checkpoint axis in patients with poor neurological outcomes after cardiac arrest
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immunology
|
A one-step CRISPR-based strategy for endogenous gene tagging in Drosophila melanogaster
|
molecular biology
|
Detection and molecular characterization of a phytoplasma associated with Cucumber (Cucumis sativus) and its first report from India
|
molecular biology
|
Transcriptional profiling from whole embryos to single neuroblast lineages in Drosophila
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developmental biology
|
Colouring coral larvae for tracking dispersal
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ecology
|
Community adaptation to temperature explains abrupt soil bacterial community shift along a geothermal gradient on Iceland
|
ecology
|
NUMT PARSER: automated identification and removal of nuclear mitochondrial pseudogenes (numts) for accurate mitochondrial genome reconstruction in Panthera
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evolutionary biology
|
Full-length dystrophin is expressed across human tissues and DMD downregulation commonly occurring in tumours coincides with Duchenne-like molecular alterations
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genetics
|
Active vision during prey-capture in wild marmoset monkeys
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animal behavior and cognition
|
Microenvironmental engineering improves the self-organization of patterned microvascular networks
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bioengineering
|
Systematic classification error profoundly impacts inference in high-depth Whole Genome Shotgun Sequencing datasets
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bioinformatics
|
recolorize: improved color segmentation of digital images (for people with other things to do)
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bioinformatics
|
A Deep Learning Method for MiRNA/IsomiR Target Detection
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bioinformatics
|
DeepVelo: Deep Learning extends RNA velocity to multi-lineage systems with cell-specific kinetics
|
bioinformatics
|
Molecular-Dynamics Simulation Methods for Macromolecular Crystallography
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biophysics
|
Characterizing the extracellular matrix transcriptome of cervical, endometrial, anduterine cancers
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cancer biology
|
3'UTR-dependent dynamic changes in TP53 mRNA localization regulate p53 tumor suppressor activity
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cancer biology
|
Increased adipose tissue indices of androgen catabolism and aromatization in women with metabolic dysfunction
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physiology
|
Electron tomography analysis of the prolamellar body and its transformation into grana thylakoids in the cryofixed Arabidopsis cotyledon
|
plant biology
|
Ralstonia solanacearum effector RipAF1 ADP-ribosylates host FBN1 to induce resistance against bacterial wilt
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plant biology
|
ASTF1, an AP2/ERF-family transcription factor and ortholog of cultivated tomato LEAFLESS, is required for acylsugar biosynthesis
|
plant biology
|
Gut microbiome-linked metabolites in the pathobiology of depression and anxiety - a role for bile acids
|
neuroscience
|
Cognitive dysfunction and anxiety resulted from synaptic downscaling, hippocampal atrophy and ventricular enlargement in i.c.v. streptozotocin injected male Wistar rats
|
neuroscience
|
Application of light-sheet mesoscopy to image host-pathogen interactions in intact organs
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immunology
|
Small silencing RNAs expressed from W-linked retrocopies of Masculinizer target the male-determining gene PxyMasc during female sex determination in the Diamondback moth Plutella xylostella
|
developmental biology
|
mRNAid, an Open-Source Platform for Therapeutic mRNA Design and Optimization Strategies
|
bioinformatics
|
Reduced stroke outcome in old-aged female mice maintained on a dietary vitamin B12 deficiency
|
physiology
|
Microglia Detect Externalized Phosphatidylserine on Synapses for Elimination via TREM2 in Alzheimer's Disease Models
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neuroscience
|
Tissue-wide Genetic and Cellular Landscape Shapes the Execution of Sequential PRC2 Functions in Neural Stem Cell Lineage Progression
|
neuroscience
|
Mice expressing P301S mutant human tau have deficits in interval timing
|
neuroscience
|
High-level motor planning allows flexible walking at different gait patterns in a neuromechanical model
|
neuroscience
|
Neural systems underlying RDoC social constructs: An activation likelihood estimation meta-analysis
|
neuroscience
|
Substance P and adenosine signaling pathways regulate exosomal sorting of miR-21 in colonic epithelial cells
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cell biology
|
Methacrylic acid-based biomaterials promote peripheral innervation in the subcutaneous space of mice
|
bioengineering
|
A Python Package for the Localization of Protein Modifications in Mass Spectrometry Data
|
bioinformatics
|
Immunopharmacological evaluation of adjuvant efficacy of Monophosphoryl lipid-A and CpG ODN with SARS-CoV-2 RBD antigen
|
immunology
|
Impact of prior infection on SARS-CoV-2 antibody responses in vaccinated long-term care facility staff
|
immunology
|
Screening of SARS-CoV-2 Antivirals Through a Cell-Based RNA-Dependent RNA Polymerase (RdRp) Reporter Assay
|
microbiology
|
Targeted protein S-nitrosylation of ACE2 as potential treatment to prevent spread of SARS-CoV-2 infection
|
microbiology
|
Evolution of Delta variant by non-Spike signature co-appearing mutations: trailblazer of COVID-19 disease outcome
|
genomics
|
Time series analysis of SARS-CoV-2 genomes and correlations among highly prevalent mutations
|
bioinformatics
|
The network of SARS-CoV-2-cancer molecular interactions and pathways
|
cancer biology
|
The E2 glycoprotein holds key residues for Mayaro virus adaptation to the urban Aedes aegypti mosquito
|
microbiology
|
Tracing carbon metabolism with stable isotope metabolomics reveals the legacy of diverse carbon sources in soil
|
microbiology
|
Divergent LD-transpeptidase-independent effects of peptidoglycan carboxypeptidases on intrinsic ss-lactam and vancomycin resistance
|
microbiology
|
The impact of PrsA over-expression on the Bacillus subtilis transcriptome during fed-batch fermentation of alpha-amylase production
|
microbiology
|
Transmission of human influenza A virus in pigs selects for adaptive mutations on the HA gene
|
microbiology
|
FLAGELLAR MOTILITY DURING E. COLI BIOFILM FORMATION PROVIDES A COMPETITIVE DISADVANTAGE WHICH RECEDES IN THE PRESENCE OF CO-COLONIZERS.
|
microbiology
|
TransCRISPR - sgRNA design tool for CRISPR/Cas9 experiments targeting transcription factor motifs
|
molecular biology
|
Parental histone distribution at nascent strands controls homologous recombination during DNA damage tolerance
|
molecular biology
|
Revealing determinants of translation efficiency via whole-gene codon randomisation and machine learning
|
molecular biology
|
CryoEM structures of the multimeric secreted NS1, a major factor for dengue hemorrhagic fever
|
molecular biology
|
Distinct regions of H. pylori's bactofilin regulate protein interactions to control cell shape
|
microbiology
|
Single-cell transcriptomics to define Plasmodium falciparum stage-transition in the mosquito midgut
|
microbiology
|
Description of Halopseudomonas maritima sp. nov., based on phylogenomic analysis
|
microbiology
|
Enhancing Prime Editing Efficiency and Flexibility with Tethered and Split pegRNAs
|
molecular biology
|
Development of ultra-low-input nanoRibo-seq enables quantification of translational control, revealing broad uORF translation by subtype-specific neurons
|
molecular biology
|
Cryo-EM Structure of R-loop monoclonal antibody S9.6 in recognizing RNA:DNA hybrids
|
molecular biology
|
m6A modification of U6 snRNA modulates usage of two major classes of pre-mRNA 5' splice site
|
molecular biology
|
Microclimate is a strong predictor of the native and invasive plant-associated soil microbiota on San Cristobal Island, Galapagos archipelago
|
microbiology
|
Comparative analysis about the structure of complete chloroplast genomes in genus Mangifera and accuracy verification about phylogenetic analysis based on gene ycf2 in genus level
|
molecular biology
|
Nucleoporins facilitate ORC loading onto chromatin
|
molecular biology
|
How to select the best model from AlphaFold2 structures?
|
bioinformatics
|
Identification of Antimalarial Compounds that Inhibit Apicomplexan AP2 Proteins
|
molecular biology
|
Protist diversity and metabolic strategy in freshwater lakes are shaped by trophic state and watershed land use at a continental scale
|
ecology
|
Non-cancer stem cell-derived Fibromodulin activates Integrin-dependent Notch signaling in endothelial cells to promote tumor angiogenesis and growth
|
cancer biology
|
Toward an optimal contraception dosing strategy
|
systems biology
|
Vascular inflammation exposes perivascular cells to SARS-CoV-2 infection
|
bioengineering
|
ViReMaShiny: An Interactive Application for Analysis of Viral Recombination Data
|
bioinformatics
|
Delineating antibody escape from Omicron variants
|
immunology
|
SARS-CoV-2 Omicron (BA.1 and BA.2) specific novel CD8+ and CD4+ T cell epitopes targeting spike protein.
|
immunology
|
Delta-Omicron recombinant SARS-CoV-2 in a transplant patient treated with Sotrovimab
|
microbiology
|
CARP2 regulates the Golgi dynamics upon EGF stimulation
|
cell biology
|
Ana1/CEP295 is an essential player in the centrosome maintenance program regulated by Polo kinase
|
cell biology
|
Introducing CELLBLOKS: a novel organ-on-a-chip platform allowing a plug-and-play approach towards building organotypic models
|
cell biology
|
Redox sensing by SENP1 augments insulin secretion early after high-fat feeding in mice
|
cell biology
|
Salicin modifies osteoarthritis progression by binding on IRE1α and inhibiting IRE1α mediated endoplasmic reticulum stress
|
cell biology
|
Conserved degronome features governing quality control-associated proteolysis
|
cell biology
|
Cryo-EM reveals an entangled kinetic trap in the folding pathway of a catalytic RNA
|
biochemistry
|
Exploring the effect of mechanical anisotropy of protein structures in the unfoldase mechanism of AAA+ molecular machines
|
biophysics
|
State Dependent Anionic Pore Currents Conducted by Single Countercharge Mutants in a Voltage-Sensing Phosphatase
|
biophysics
|
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