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252,960,071 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.54691/bcpbm.v26i.1996",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "HYBRID",
"url": "http://bcpublication.org/index.php/BM/article/download/1996/1993"
}
|
This paper aims to analyze the current condition of high technology manufacturing in China in the context of a trade war between it and the U.S. Since China and the U.S. are the largest two manufacturing countries and also the highest GDP countries, the paper presents the trend of the manufacturing within these two countries and their comparative advantage. While Chinese manufacturing wins by large scale and low production cost, U.S. manufacturing wins by its control of high technology which is more valuable to manufacturing growth today. Given the ever-intense rivalry between China and the U.S. on high-end technology manufacturing, the paper then discusses the resulted difficulty faced by China as it is experiencing a high-tech supply shortage and the solution China has used to conquer the obstacles. The solution China employed has shown its effectiveness as several high-end manufacturing areas have achieved great progress in the year after the solution was imposed. The content of the paper is meaningful to the study of the relationship between China and the U.S. and the continuing growth of Chinese manufacturing as it records the biggest tension between the two countries and the resolution China takes to save its manufacturing from a broken technology supply chain.
|
2022-10-19T19:38:03.307Z
|
100,794,839 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1107/S0108767307098819",
"MAG": "2329043311",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
24 European Crystallographic Meeting, ECM24, Marrakech, 2007 Page s55 Acta Cryst. (2007). A63, s55 MS21 O3 Crystal structure of RbWOP2O7 a new diphosphate W(V) isotypic with KWOP2O7 D. Mezaoui, S. Belkhiri, R. Belhouas, A. Leclaire, H. Rebbah. a Laboratoire des Sciences des Materiaux, Faculte de Chimie, USTHB, BP 32 El-Alia, 16111 Bab-Ezzouar, Alger, Algerie. b Laboratoire de Cristallographie et Sciences des Materiaux, CRISMAT, ENSICAEN, Campus II,6, Boulevard du Marechal Juin, 14050 Caen Cedex, France.
|
2022-11-11T08:23:02.875Z
|
106,065,708 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/00032719.2018.1498506",
"MAG": "2858960369",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract A chemiluminescent method was developed for microRNA-141 (miRNA-141) detection based on the target-dependent activation of peroxidase-mimicking DNAzyme. The structure of the probes was optimized which allowed the development of a sensitive method for miRNA-141. Under the optimized conditions, the detection limit and the linear range were 100 pM and 0.1–50 nM, respectively. The sensitivity of the assay was 270,000 nM−1. The values of coefficient of variation measured within the working range varied less than 2%, which indicates excellent precision for the proposed method.
|
2022-12-16T04:17:58.749Z
|
83,964,501 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1071/WR9830185",
"MAG": "1992472567",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Low-density nesting by hawksbill turtles at Campbell I., Torres Strait, is described. The average female measured 83.2 cm in carapace length, weighed 51.6 kg and laid three clutches per season with a renesting interval of 14.7 days. The average clutch contained 131.8 eggs, mean egg weight was 26 g and mean diameter was 3.6 cm. Hatchling weight was 14.3 g, mean period to emergence was 55 days. Varanid predation is described. Scute variation of adults and hatchlings is summarized.
|
2022-12-19T08:44:27.529Z
|
44,638,873 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CHICC.2006.4346999",
"MAG": "2071877749",
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},
"license": null,
"status": null,
"url": null
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|
In order to exert the potential of mine hoist, a kind of control system is designed by use of integrating fault diagnosis with fault tolerate, according to the property of mine hoist control system. It can auto-monitor, diagnose and tolerant control .It advises that tolerant control can be realized by use of the integrated intelligent sensor tolerant control scheme in the control system of mine hoist. It can assure the mine hoist run stably under the sensor fault and avoid accident. The concrete mode is discussed to realize the whole and the part of the tolerant control system of mine hoist which bases on the fuzzy neural network. The system is simulated and the result proves the system is of characteristic of tolerant control and reliability.
|
2022-02-12T01:14:28.587Z
|
32,684,151 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3760/J.ISSN:0412-4081.2007.12.017",
"MAG": "2403553969",
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},
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"status": null,
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|
OBJECTIVE
The present study was undertaken to examine the expression of pigment epithelium-derived factor (PEDF) in the retina of adult rat following hypobaric hypoxic exposures.
METHODS
Forty-eight adult Wistar rats were divided into 6 groups randomly (8 rats in each group), of which 5 groups (40 rats) were subjected to hypobaric hypoxia for 2 hours following which expression of PEDF in the retina was investigated from 3 hours to 14 days by real time RT-PCR, western blotting and immunohistochemistry.
RESULTS
PEDF mRNA and protein expression in the retina was decreased at 3 hours to 14 days following exposure to hypoxia. Compared with normal control group (1.00+/-0.00), PEDF mRNA expression decreased to 0.83+/-0.05 at 3 hours, 0.72+/-0.04 at 24 hours, 0.56+/-0.04 at 3 days, 0.54+/-0.05 at 7 days and 0.49+/-0.05 at 14 days respectively; Compared with normal control group (1.90+/-0.02), PEDF protein expression decreased to 1.49+/-0.02 at 3 hours, 1.19+/-0.05 at 24 hours, 1.15+/-0.05 at 3 days, 1.09+/-0.06 at 7 days and 1.07+/-0.03 at 14 days respectively.
CONCLUSIONS
The findings of this study indicate hypoxia can downregulate PEDF in adult retina.
|
2022-02-12T10:50:12.284Z
|
151,802,765 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.17074/LINGUISTICA.V11I1.640",
"MAG": "2528325333",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Brazilian Portuguese exhibits variable patterns of nominal and verbal number morphological agreement: (i) redundant marking in the full DP and in verbal suffix; (ii) non-redundant agreement, with plural morphology in D. This paper focuses on adult processing of variable agreement in a psycholinguistic point of view; the topic is empirically investigated by means of a self-paced listening task. The results showed longer listening times in the non-standard agreement conditions and suggest that, even when the non-standard rule is well accepted, the absence of the repeated marks may be more cognitively demanding when compared with the standard agreement pattern. DOI: 10.17074/2238-975X.2015v11n1p118
|
2022-02-09T03:13:26.477Z
|
72,954,611 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1702/1304.14418",
"MAG": "2156671346",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
I clismi con fosfato sono ampiamente
utilizzati, sia per la costipazione sia per la pulizia del
colon come preparazione per procedure endoscopiche e chirurgiche,
in adulti e bambini. Molti studi sottolineano come
l’utilizzo di questa sostanza sia da ritenersi rischioso. Obiettivi.
Definire possibili strategie di prevenzione a partire da
un evento avverso verificatosi in seguito alla somministrazione
ripetuta del farmaco. Metodi. E stato formato un gruppo
di lavoro, rivista la letteratura e sono state formulate,
condivise e discusse le raccomandazioni per un utilizzo appropriato
degli enteroclismi ed e stata modificata l’organizzazione
per migliorare la sicurezza dei pazienti. Risultati. I
clisteri a base di fosfati sono stati sostituiti con clismi da
125 ml a base di acqua, sono state emanate delle raccomandazioni
che ne limitano fortemente l’uso e sono stati
messi a confronto i consumi di lassativi nel primo e secondo
semestre 2012, dimostrando la modifica dell’uso ed in
particolare la riduzione dell’uso di clisteri a base di fosfati.
Conclusioni. Una serie di interventi a piu livelli, a partire da
un evento avverso, ha modificato l’uso di lassativi e clismi
a base di fosfati.
|
2022-02-11T09:30:56.264Z
|
240,436,028 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21203/rs.3.rs-946601/v1",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GREEN",
"url": "https://www.researchsquare.com/article/rs-946601/latest.pdf"
}
|
Flash drought (FD) is characterized by the rapid onset and development of drought conditions. It usually occurs during the growing seasons, causing more severe impacts on agriculture and society than the slowly-evolving droughts. Based on the Standard Evaporative Stress Ratio (SESR), this study presents an assessment of the spatio-temporal variability of the joint return periods of FD characteristics in the Pearl River basin (PRB), southern China. Three FD characteristics (i.e., duration D, intensity I, peak P) are extracted at each 0.25o×0.25o grid point over the PRB by the Runs theory. Four marginal distribution functions (Gamma, Exponential, Generalized Extreme Value and Lognormal) are used to fit FD characteristics, while three Archimedean Copula functions (Clayton, Frank and Gumbel) are used for generating the joint distributions of various paired FD characteristics. The results indicate that Lognormal is the best-fitted marginal distribution function of FD characteristics in most parts of PRB, while Frank and Clayton are the best-fitted Copula of the joint PDFs of three pairs of FD characteristics in most parts of PRB. During 1953–2013, the FD events are more frequent in eastern PRB (> 40 events) than western PRB (<10 events), and larger FD characteristics (D and I) are also found in eastern PRB than western PRB. The return period of each FD characteristic is smaller in eastern PRB than western PRB, leading to smaller joint return periods of three paired FD characteristics (D-I, D-P, P-I) in eastern PRB than western PRB. Overall, our results suggest that the risk of FD is gradually increased from the west to the east of the PRB.
|
2022-07-31T05:00:25.507Z
|
234,314,877 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.22271/27069567.2021.V3.I1A.88",
"MAG": "3126351476",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Introduction: Liver cirrhosis is an unique clinical entity in which long-term diabetes mellitus (DM) can predispose individuals to cirrhosis and, on the other hand, long-term cirrhosis of the liver can predispose cirrhosis to DM, secondary to glucose and insulin metabolism. Aims: The aim of this study is to determine the prevalence of insulin resistance in liver cirrhosis.Materials and Methods: This cross sectional case control study conducted in department of medicine in 80 patients for duration of 1 year. All cirrhotic patients irrespective of aetiology were subjected to fasting plasma glucose level and fasting plasma insulin levels and insulin resistance was calculated by HOMA-IR method. Study was statistically analysed.Results: Insulin resistance was found in 62 cases with IR in ratio in 1.64 is 4.6+2.9. with p value is
|
2022-12-13T16:13:48.616Z
|
121,406,930 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1143/JJAP.47.8898",
"MAG": "2020263530",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We calculated the thermal conductivity of SiC by molecular dynamics simulation and investigated the effects of impurities on the thermal conductivity of SiC. We used Tersoff potential to express the structure of a SiC crystal. Thermal conductivity was obtained using Green–Kubo's equation. The results show that the thermal conductivities of perfect 2H-, 3C-, 4H-, and 6H-SiC polytypes were in the range of 260 to 420 W/(m·K) and that the thermal conductivity of 3C-SiC was the largest among the polytypes. The thermal conductivities of 4H-SiC decreased with an increase in impurity concentration above 1.0×1017 to 1.0×1018 1/cm3.
|
2022-12-14T05:06:13.738Z
|
22,550,296 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/10629360412331297371",
"MAG": "1989936786",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Recent policy developments in the European union (EU) and within the Organisation for Economic Cooperation and Development (OECD) have placed increased emphasis on the use of structure-activity relationships (SARs) and quantitative structure-activity relationships (QSARs), collectively referred to as (Q)SARs, within various regulatory programmes for the assessment of chemicals and products. The most significant example within the EU is the European commission's proposal (of 29 October 2003) to introduce a new system for managing chemicals (called REACH), which calls for an increased use of (Q)SARs and other non-animal methods, especially for the assessment of low production volume chemicals. Another development within the EU is the Seventh Amendment to the Cosmetics Directive, which foresees the phasing out of animal testing on cosmetics, combined with the imposition of marketing bans on cosmetics that have been tested on animals after certain deadlines. At the same time, the Existing Chemicals programme within the OECD is investigating ways of increasing the use of chemical category approaches, which depend heavily on the use of (Q)SARs, activity-activity relationships and read-across. Such developments are placing an enormous challenge on industry, regulatory bodies, and on the European commission's Joint Research Centre (JRC), which is responsible for providing independent scientific advice to policy makers in the European Commission and the Member States. This paper reviews the different scientific and regulatory purposes for which reliable (Q)SARs could be used, and describes the current work of the JRC in providing scientific support for the development, validation and implementation of (Q)SARs.
|
2022-12-12T21:47:52.909Z
|
8,559,108 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/WSC.2009.5429238",
"MAG": "2135974688",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this paper we describe the optimization of a facility layout scenario, which involves coupling simulation with the optimization environment HeuristicLab. For this purpose we show a problem formulation that acts as an interface between these two domains of problem modeling and optimization, and discuss optimization methodologies and their results for a number of artificial test problems as well as more complex real-world problems. HeuristicLab was designed with both practitioners and algorithm developers in mind. Practitioners benefit from a graphical user interface that facilitates so-called interactive algorithm engineering, where algorithms can be adjusted without actually writing code. Algorithm developers are aided in the development process by the plug-in based, easily extensible architecture and integrated parallelization functionality.
|
2022-12-15T14:02:07.236Z
|
22,179,069 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/00043426-199807000-00008",
"MAG": "2007490535",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Purpose: Some children who survive a childhood malignancy have diminished bone mineral density (BMD). The purpose of this study is to assess when, and perhaps why, this problem develops. Patients and Methods: BMD was longitudinally monitored in 37 children for a minimum of 1 year (mean, 23.4 months; range, 12 to 41 months) during and, in some cases, after chemotherapy. Evaluations included serum analyses (vitamin D, calcium, and alkaline phosphatase), assessment of calcium intake, and measures of growth and nutrition (height, weight, and skinfolds). Results: BMD was already diminished at the start of treatment in some patients; 6 of 13 patients (46%) had a BMD score in the hip or spine of < - 1.0. However, only 1 patient (8%) was < - 2.0. Most patients did not have a significant drop in BMD z scores during chemotherapy, but one in four did decrease at least 0.5 standard deviations. Age greater than 10 years, a drop in height z score, and treatment with cranial irradiation correlated with a drop in BMD z scores during treatment. In the year immediately after completion of chemotherapy, no consistent “catch-up” was observed in BMD Z scores. Conclusions: In some patients, BMD Z scores are diminished at the time of diagnosis and a drop may occur during treatment in others. Multiple factors related to the disease process and treatment likely contribute to these observations. Cranial irradiation, perhaps by impacting on growth hormone homeostasis, is one such factor. Fortunately, most survivors of a childhood malignancy will not have large deficits in BMD later in life.
|
2022-12-18T02:38:38.606Z
|
121,159,631 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1117/12.150197",
"MAG": "2041080533",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In order to study the motion of non-rigid objects in an image sequence, it is often necessary to compute a dense optical flow field. Gradient-based techniques have been relatively successful at computing dense flow fields for gray-scale images when additional constraints are added. However, these constraints often introduce errors at the edges of objects, where the object motion is different from the background motion. Our approach is to use color images to obtain three constraint equations corresponding to three color components. This gives us an overdetermined linear system with three equations and two unknowns (x and y direction components of optical flow) which can be solved using linear least-squares algorithm. No further constraints are necessary. This paper presents such a color-based optical flow estimation and includes some initial promising results on synthetic motion image data. Further research directions are also discussed.
|
2022-12-19T12:58:08.618Z
|
22,556,822 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1097/00000658-200204000-00012",
"MAG": "2092646943",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1422469"
}
|
ObjectiveTo determine the long-term results of liver transplantation for hepatocellular carcinoma (HCC) measuring 5 cm or larger treated in a multimodality adjuvant protocol. Summary Background DataTransplant has been established as a viable treatment of HCC measuring less than 5 cm, but the results for larger tumors have been disappointing. Several studies have shown promising preliminary results when combining transplant with preoperative transarterial chemoembolization and/or perioperative systemic chemotherapy in the treatment of advanced HCC that is not amenable to resection. However, follow-up in the studies has been limited and the number of patients has been small. MethodsBeginning in October 1991, all patients with unresectable HCC measuring 5 cm or larger, as measured by computed tomography, were considered for enrollment in the authors’ multimodality protocol. Entry criteria required that all patients be free of extrahepatic disease based on computed tomography scans of the chest and abdomen and bone scan and have a patent main portal vein and major hepatic veins on duplex ultrasonography. Patients received subselective arterial chemoembolization with mitomycin C, doxorubicin, and cisplatin at the time of diagnosis, repeated as necessary based on tumor response. Patients received a single systemic intraoperative dose of doxorubicin (10 mg/m2) before revascularization of the new liver and systemic doxorubicin (50 mg/m2) every 3 weeks as tolerated, for a total of six cycles, beginning on the sixth postoperative week. ResultsEighty patients were enrolled; 37 were eventually excluded, due mainly to disease progression while on the waiting list, and 43 underwent liver transplant. Mean pathologic tumor diameter was 5.8 ± 2.7 cm. Median follow-up of surviving transplanted patients was 55.1 ± 24.9 months. There were two (4.7%) perioperative deaths. Median overall survival was significantly longer in transplanted patients (49.9 ± 10.42 months) than in those who were excluded (6.83 ± 1.34 months). Overall and recurrence-free survival rates in transplanted patients at 5 years were 44% and 48%, respectively. A tumor size larger than 7 cm and the presence of vascular invasion correlated significantly with recurrence. Recurrence-free survival at 5 years was significantly higher for the 32 patients with tumors measuring 5 to 7 cm (55%) than the 12 patients with tumors larger than 7 cm (34%). ConclusionsA significant proportion of patients with HCC measuring 5 cm or larger can achieve long-term survival after liver transplantation in the context of multimodal adjuvant therapy. Patients with tumors measuring 5 to 7 cm have significantly longer recurrence-free survival compared with those with larger tumors.
|
2022-12-21T04:05:32.460Z
|
239,381,742 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.24136/atest.2018.405",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "http://economic-research.pl/Journals/index.php/atest/article/download/1241/1196"
}
|
The article presents the test of immunity to electric surges of two surge arresters used in railway electronic systems. Metering methodology, laboratory stand according to PN-EN 61000-4-5 and expo-sure levels included in the railway standard PN-EN 50121-3-2 are presented. The article presents examples of research results and an evaluation of the obtained results according to the applicable regulations.
|
2022-01-27T05:09:11.157Z
|
195,476,330 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.20527/QUANTUM.V7I1.3545",
"MAG": "2948063990",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract. This study aimed to determine the effect of the learning model of blended learning generic skills learning outcomes in the modeling and chemical materials. This study used a quasi-experimental methods (quasi experiment) with the draft nonequivalent control group design. The independent variables in this study is a learning model of blended learning and conventional learning models, while the dependent variable is the generic skills learning outcomes modeling and chemistry. Subjects were students of SMA Negeri 5 Banjarmasin grade XI totaling 149 students. Sampling was done by cluster random sampling, a class XI IPA 4 as the control class and XI IPA 2 as the experimental class. The data collection technique using the test results of study, observation and student questionnaire responses. Data were analyzed using normality test, homogeneity test, t-test and N-gain. The results showed that the influence of blended learning models to modeling generic skills and student learning outcomes. Results obtained t t-test of 4.41 is greater than the price Ftable is at 2.00, it indicates that there are differences in generic skills modeling dabn significant student learning outcomes after learning blended learning models. Based on the results of data analysis can be concluded that the application of blended learning models in chemical material effect on modeling generic skills and student learning outcomes SMA Negeri 5 Banjarmasin. Keywords: Blended Learning Model, the conventional model, modeling and generic skills learning outcomes
|
2022-02-08T07:52:06.258Z
|
51,641,588 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1109/T-AIEE.1915.4765215",
"MAG": "2036833631",
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},
"license": null,
"status": null,
"url": null
}
|
The author describes a permanent installation which was made for supplying moisture to the earth in the neighborhood of underground cables with the object of reducing their temperature. The approximate temperature of the cables is found by taking with a resistance thermometer the temperature of a duct adjacent to the cable which is the source of heat. In uncovering the conduits and exposing them to air, as a remedy for hot spots in the cable, it was found that the adjacent earth was hot and dry so that it crumbled to powder. This suggested opening a ditch in the ground above the conduit and directing a stream of water through it. This was found to lower the temperature immediately several degrees. Where an open conduit was not practical, water was discharged into a vacant cable duct by means of a hose and this was found to be more effective than the open ditch method. These experiments led to the installation of a line of porous tile duct in the earth above the conduit, surrounded with clean sand. The leakage of water through the pores of this duct has been found very effective in reducing the temperature of the cables. Whenever the temperature of the cables is found by exploring with a resistance thermometer to approach the danger point, water is turned into the porous drain tile, and the temperature is taken on successive days to see whether the desired reduction has been obtained.
|
2022-07-09T06:51:53.319Z
|
70,426,833 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.17533/UDEA.RFNSP.V33N3A07",
"MAG": "2288546463",
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},
"license": null,
"status": null,
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}
|
Objetivo: identificar la percepcion que tienen los actores frente a los atributos del sistema de vigilancia de las exposiciones rabicas para generar las recomendaciones que se requieran. Metodologia: se utilizo la teoria fundada hasta analisis de categorias interpretativas; once entrevistas semiestructuradas enmarcadas en los atributos considerados por los Centros de Control y Prevencion de Enfermedades (cdc) para la evaluacion de sistemas de vigilancia se realizaron a personas con un rol activo (desde notificacion hasta administrador del sistema), en los departamentos con mayor y menor notificacion del evento en el pais. Resultados: emergieron catorce categorias descriptivas relacionadas con los nueve atributos, sistema de vigilancia, rabia y propuestas para la mejora; de estas, cinco categorias analiticas las enmarcan con recursos para la operacion, experiencia, control directo de la rabia y papel de los actores en el proceso. Se destaco la importancia del sistema en la recoleccion de informacion en Salud Publica; se desconocen publicaciones relacionadas y se percibio como baja la participacion de los actores en la planificacion. Se manifestaron dificultades con la calidad de la informacion: clasificacion de casos, afectando la representatividad y sensibilidad. La aceptabilidad se relaciona con las tareas del sistema y el tiempo dedicado al proceso. La oportunidad varia en procesos de notificacion y ajuste. Conclusiones: la percepcion sobre los atributos denota la articulacion de conceptos del sistema y la experiencia adquirida; aspectos positivos como representatividad e historia y negativos relacionados con calidad, sensibilidad, utilidad y aceptabilidad. Recomendaciones: realizar publicaciones y mejorar la participacion en la planificacion del sistema.
|
2022-09-02T03:09:15.872Z
|
100,161,294 |
{
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"ArXiv": null,
"DOI": "10.1063/1.4963283",
"MAG": "2526226872",
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},
"license": null,
"status": "GREEN",
"url": "http://ira.lib.polyu.edu.hk/bitstream/10397/66649/1/Gao_Unveiling_Carbon_Dimers.pdf"
}
|
Carbon precursor that forms on the catalyst surface by the dissociation of feedstock gas plays an important role in the controllable growth of graphene on metal substrates. However, the configuration about the precursor has so far remained elusive. Here, we report the direct observation of uniformly structured precursor units and their chain formation at the nucleation stage of graphene growing on Ru(0001) substrate by using scanning tunneling microscopy. Combining this experimental information with density function theory calculations, the atomic-resolved structures of carbon precursor are characterized as adsorbed CH2 segments on the substrate. The dissociated carbon feedstock molecules or radicals further react to form nonplanar -[C2H4]- chains adsorbed on hexagonal-close-packed hollow sites of the Ru(0001) substrate before incorporating into the graphene island. These findings reveal that CH2 and nonplanar -[C2H4]- segments act as precursors in graphene growth and are helpful to improve the quality an...
|
2022-09-07T17:53:18.749Z
|
108,440,250 |
{
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"DOI": "10.1080/20786204.2007.10873641",
"MAG": "1966747169",
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},
"license": null,
"status": "BRONZE",
"url": "https://www.tandfonline.com/doi/pdf/10.1080/20786204.2007.10873641?needAccess=true"
}
|
Abstract The Aviation Medicine Department of the South African Civil Aviation Authority (SACAA), Aviation Medical Examiners (AME), and Institute for Aviation Medicine (IAM) receive numerous inquiries regarding the use of medication in the aviation environment. Flying an aircraft or controlling aircraft on the ground are highly demanding cognitive and psychomotor tasks, performed in an often inhospitable environment, with exposure to various sources of stress. It is therefore important for aviation personnel (i.e. aviation medical examiners, pilots, cabin crew and air traffic services personnel) to consider the effects that medicine or drugs may have on performance. Studies confirm that some pilots, and other crew members while on duty, used prohibited medications or illegal substances or performed duties while suffering significant unreported medical conditions. When considering aircraft mishaps and their causes, we tend to focus on the pilot. After all, he's in the driver's seat, there to troubleshoot any problems that may arise, and he's expected to bring the “on-loan” aircraft back to base, in one piece, after a mission. If a mishap occurs, investigators look for causes related to pilot error along with evidence of mechanical failure, weather factors, and runway condition and air traffic control (ATC) issues. Reviews of data from general aviation, commercial and military aircraft mishaps show that the two most often cited causal issues are pilot error and mechanical/logistical factors. If pilot error was identified, the question now arises: Are some instances of incorrect controlling of an aircraft due to human factors, such as poor diet or insufficient rest (self-imposed), fatigue, poor concentration, shift-work problems, inadequate training or lack of motivation? More specifically, the following in terms of pilot error have been identified in the USA: • Flying under the influence of alcohol—15%• Conducting unwarranted manoeuvers—30%• Penetrating known adverse weather conditions beyond pilot and aircraft capabilities—40%• Drug impairment of the pilot (includes prescribed medication)—6%• Miscellaneous—9% Although these statistics relate to the pilot, they can no doubt be extended to other aviation personnel e.g. ATC, cabin crew (CC) and aircraft maintenance officers (AMO). Of note is that up to 6% of aircrew are ‘under the influence of medication’ while operating an aircraft. Aircrew, like all of us, are prone to illness, but those who take medicine on an inadequately informed basis or undertake self-medication, not only endanger their lives but also jeopardise the safety of passengers and costly aircraft. The Aviation Medicine Department of the South African Civil Aviation Authority, Aviation Medical Examiners, and the Institute for Aviation Medicine receive numerous inquiries regarding the use of medication in the aviation environment. In addition, reports have been received relating to aviation personnel using unapproved medication or illegal drugs. Furthermore, a physician may prescribe medication for a patient while being unaware that the patient is performing duties within the aviation environment. Or, a pilot self-medicates because consulting an AME may result in flying privileges being withdrawn. Flying an aircraft or controlling aircraft on the ground are highly demanding cognitive and psychomotor tasks, performed in an inhospitable environment, with exposure to various sources of stress. It is therefore important for aviation personnel (i.e. aviation medical examiners, pilots, cabin crew and air traffic controllers) and non-aviation medical examiners to consider the effect that medicine or drugs may have on aviation performance. A study performed in 1994 by the FAA revealed that an estimated 14 000 US pilots flew while using prohibited medications or illegal substances or flew with significant unreported medical conditions.1 Greater understanding of the effects of medication in humans, and advances in drug development have now made possible the use of various medications by aircrew. In this context assessment of side effects which a drug may have on performance, has become an important part of its clinical profile and provides increased and more informed availability of potential therapy for aircrew. The aim of this review is to make the non-aviation medical examiner aware of, and to provide an understanding of the issues involved rather than to provide recommendations for drug use in aviation and to outline the various approaches that can be adopted to assess whether a drug can be used safely.
|
2022-01-27T13:32:20.151Z
|
235,670,482 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1145/3453142.3491276",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Large-scale real-time analytics services continuously collect and analyze data from end-user applications and devices distributed around the globe. Such analytics requires data to be transferred over the wide-area network (WAN) to data centers (DCs) capable of processing the data. Since WAN bandwidth is expensive and scarce, it is beneficial to reduce WAN traffic by partially aggregating the data closer to end-users. We propose aggregation networks for performing aggregation on a geo-distributed edge-cloud infrastructure consisting of edge servers, transit and destination DCs. We identify a rich set of research questions aimed at reducing the traffic costs in an aggregation network. We present an optimization formulation for solving these questions in a principled manner, and use insights from the optimization solutions to propose an efficient, near-optimal practical heuristic. We implement the heuristic in AggNet, built on top of Apache Flink. We evaluate our approach using a geo-distributed deployment on Amazon EC2 as well as a WAN-emulated local testbed. Our evaluation using real-world traces from Twitter and Akamai shows that our approach is able to achieve 47% to 83% reduction in traffic cost over existing baselines without any compromise in timeliness.
|
2022-11-22T14:17:57.281Z
|
41,081,891 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1136/bmj.2.5349.83",
"MAG": "2029557098",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc1872177?pdf=render"
}
|
Two skulls were also cracked through lack of precautions. Now there is evidence that non-traumatic risks are present which if numerically fewer are no less unpleasant or hazardous. Summary The foregoing occurrence of acute pulmonary oedema with neurological disturbance followed promptly after completing the " mess trick " and the "fainting lark." Syncope in each case occurs through well-established physiological vascular changes. Lung trauma is considered to be an improbable cause of pulmonary oedema. Neither cerebral thrombosis nor cerebral haemorrhage is thought to be likely as a cause of neurological disturbance. A proved connexion exists between pulmonary oedema and cerebral damage: both conditions have been confirmed at post-mortem examination. With lesser degrees of cerebral damage recovery from pulmonary oedema may occur. The infliction of discrete lesions to the hypothalamic pre-optic nuclei in experimental animals is regularly followed by acute and severe pulmonary oedema. Uninhibited vasomotor impulses in these animals will move blood from regions of high contrictor potential into lung vessels possessing low constrictor potential. The pulmonary oedema that follows is essentially neuro-haemodynamic in origin. By applying to man the principle elicited by this experimental work, an unusual symptom-complex after the fainting lark or mess trick becomes understandable. The presence is postulated, in these people, of unsuspected anatomical and morphological anomalies in the ultimate arterial supply to the hypothalamus and upper brain-stem; this, coupled with the very marked reduction in overall cerebral blood flow that accompanies a dedicated performance of the fainting lark, is calculated to deprive of blood both the oedemagenic centre in the hypothalamus (presumed to exist in man) and parts of the upper brainstem. It would be tantamount to their sustaining arterial shutdown. Therefore this reversible neural disturbance most probably causes neuro-haemodynamic changes which result in pulmonary oedema and a variable neural dysfunction in the upper brain-stem.
|
2022-12-10T09:35:14.708Z
|
213,248,370 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.18494/sam.2019.2584",
"MAG": "2990768290",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://myukk.org/SM2017/sm_pdf/SM2054.pdf"
}
|
The result of vegetation cover classification greatly depends on the classification methods. Accuracy analysis is mostly performed using the error matrix in remote sensing. In recent remote sensing, image classification has been carried out on the basis of deep learning. In the field of image processing in computer science, Intersection over Union (IoU) is mainly used for accuracy analysis. In this study, the error matrix, which is frequently used in remote sensing, and IoU, which is mainly used for deep learning images, were compared and reviewed to analyze their accuracy levels for the results of vegetation index calculation. The results of vegetation index calculation were applied to the comparison of the accuracy levels of IoU and the error matrix. According to the results of accuracy analysis using the error matrix, which is based on random points, the accuracy of the normalized difference vegetation index (NDVI) was shown to be 82.4% and that of deep learning was shown to be 93.7%, with a difference of about 11.3%. pattern machine
|
2022-12-12T19:29:53.745Z
|
15,753,370 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1145/355045.355065",
"MAG": "1488761098",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Designing architectural frameworks without the aid of formal modeling is error prone. But, unless supported by analysis, formal modeling is prone to its own class of errors, in which formal statements fail to match the designer's intent. A fully automatic analysis tool can rapidly expose such errors, and can make the process of constructing and refining a formal model more effective.
This paper describes a case study in which we recast a model of Microsoft COM's query interface and aggregation mechanism into Alloy, a lightweight notation for describing structures. We used Alloy's analyzer to simulate the specification, to check properties and to evaluate changes. This allowed us to manipulate our model more quickly and with far greater confidence than would otherwise have been possible, resulting in a much simpler model and a better understanding of its key properties.
|
2022-12-12T09:45:28.660Z
|
96,612,879 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/1536383X.2015.1009045",
"MAG": "2163773989",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Fullerene–polymer composites may find applications in different areas, particularly, in membrane technology. The formation of bonds between molecules of C60 fullerene and poly(phenylene isophtalamide) (PA) in PA-C60 composites was investigated. Powder-like PA-C60 mixtures, ultrafiltration membranes and nonporous thin films were studied by extracting C60 from the samples with various solvents. It was found that two types of fullerene coexist in the studied composites: the free (easily extractable) fullerene and the bound molecules. The percentage of extractable C60 in a given sample depends on sample composition and the method used for obtaining this nanocomposite material. An important factor in increasing the C60-PA bond strength is the duration of the material formation procedure. The quantitative processing of digital photographs of membranes, scanning electron microscopy (SEM), and electron spectroscopy for chemical analysis (ESCA) data showed that the free C60 is mainly located close to the active membrane surface. The bound C60 molecules are distributed throughout the membranes and films.
|
2022-12-18T13:57:10.297Z
|
97,162,528 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/01932690903223559",
"MAG": "2058604704",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The effects of drug-surfactant and polymer on the acid hydrolysis of acetohydroxamic acid (AHA) have been studied at room temperature in 2% (v/v) dioxane medium. Kinetic data corresponding to the reaction with drug micelles are analyzed by using the pseudo-phase ion exchange model. The binding constant and first-order rate constant in micellar media in presence of AMYTP+-Drug, AMYTP+-β-Cyclodextrine, AMYTP+-SDS, AMYTP+-PEG, AMYTP+-TX-100, AMYTP+-CTAB, have been studied in 0.5 M HCl media.
|
2022-02-10T13:41:30.035Z
|
234,287,519 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/1528083721988964",
"MAG": "3122410125",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Fast and facile one-step preparation of paraffin/polyacrylonitrile hybrid nanofibers via single needle (uniaxial) electrospinning system was studied. As-spun paraffin/polyacrylonitrile nanofibers were used for thermal hysteresis enhancement of paraffin actuators. Solid paraffin with the melting point of 32, 58, 89 and 114°C were employed for the preparation of the paraffin/polyacrylonitrile nanofibers. Differential scanning calorimetry measurements revealed that the melting point of the paraffin in paraffin/polyacrylonitrile hybrid nanofiber was clearly detectable and the melting entalpy coming from the paraffin part gradually increased from 9.6 to 101.5 J/g with the increase in the melting points of the added same amount of paraffins in paraffin/polyacrylonitrile nanofibers. When both calorimetric and weight loss measurements were considered, the paraffin which has the melting point of 32°C was found to be suitable to produce hybrid nanofibers paraffin actuator. Therefore, this hybrid nanofiber was selected for the application in paraffin actuators for e-vehicle battery cooling systems where the battery temperature must be kept between 15 and 35°C. Paraffin compound of the paraffin actuators was prepared with a mixture of pure paraffin and paraffin/polyacrylonitrile nanofiber with the wt.% of 2.5, 5, 7.5 and 10. In the hysteresis measurements, the hysteresis value at 3 mm stroke was successfully enhanced as 1.7, 3.4, 11.9 and 15.3% sequentially for the samples produced with the above ratios. Beyond hysteresis enhancement, the phenomena of thermal percolation threshold effect and thermal conductivity contrast ratio effect in nano scale were emprically exposed on opening and closing behavior of the paraffin actuator.
|
2022-07-31T08:02:50.873Z
|
203,566,388 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/SSRR.2019.8848936",
"MAG": "2976820132",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this work, we address the design, estimation, planning, control, and mapping problems to allow a small scale quadrotor to autonomously inspect the interior of a Containment Vessel (CV) test fixture, using on-board lighting, computation and sensing. We demonstrate a fully autonomous, 160 cm tip-to-tip, 236 gram Micro Aerial Vehicle (MAV) performing a complex flight mission inside of a dark test fixture that was built from a scale model of a CV. The proposed solution opens up new ways to inspect nuclear power plants and has the potential to support nuclear decommissioning, which is well known to be a dangerous, long, and tedious process. Experimental results show the ability to navigate under dripping water conditions and inside a completely dark, full-scale CV test fixture while concurrently avoiding known and unknown obstacles.
|
2022-09-05T18:49:46.821Z
|
24,493,564 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/ja209679c",
"MAG": "1969197161",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Iridium complexes show high catalytic activity in intermolecular additions of acid chlorides to terminal alkynes to afford valuable (Z)-β-chloro-α,β-unsaturated ketones. Ligands in the catalytic system play a crucial role in this reaction. An N-heterocyclic carbene (NHC) is an efficient ligand for the addition of aroyl chlorides, while dicyclohexyl(2-methylphenyl)phosphine (PCy(2)(o-Tol)) is indispensable for the reaction of aliphatic acid chlorides. The addition reactions proceed regio- and stereoselectively with suppression of decarbonylation and β-hydrogen elimination, which have been two major intrinsic problems in transition-metal-catalyzed reactions. Stoichiometric reactions of active iridium catalysts with aroyl chlorides and aliphatic acid chlorides are carried out to gain insights into the reaction mechanisms.
|
2022-11-13T04:35:32.888Z
|
55,326,945 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.9790/0837-2108111018",
"MAG": "2508300617",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://doi.org/10.9790/0837-2108111018"
}
|
Nembe Se is a traditional Kingdom in the Southern part of Nigeria, East of the Niger Delta. They occupy all the Nembe speaking communities in Nembe and Brass Local Government Area of Bayelsa State in Nigeria. The Niger Delta region is a unique ecological zone in Nigeria with an area covering approximately 70,000 square kilometres and makes up to 7.5% of Nigeria's land mass. It is politically made up of more than 40 ethnic groups and about 250 different dialects. The region is rich in natural resources embedded in their environment and culture which is seen in their social, political, cultural, religious, economic and traditional systems on daily bases, making it a viable tourist attraction if well preserved. The region is posed with a threat to these treasures, hence the ardent need for an alternative means to promote, protect and preserve these resources for tourism, education, research and development, for sustainability. Textiles as a very mobile art is a distinctive human production considered as an ultimate form of material culture and a primary form of documenting indigenous source materials and revealing the identity, history, culture and environment of a people. These could be preserved, reproducing same through such artistic expression as decorative arts, theatrical arts and clothing, leading to industrialization. This paper looks at the cultural heritage of the Niger Delta people with the aim of documenting them in visual form on textiles. Design on textiles from different cultures and the Niger Delta are compared and analyzed with visuals, and a means of preserving them is suggested. The paper observed that the rich cultural heritage of the Niger Delta people if preserved on textiles will serve as a major instrument in their socio-economic development as seen in other nations if the industry and tourism sector is developed and sustained.
|
2022-11-12T18:39:06.156Z
|
43,057,656 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1055/s-0034-1365020",
"MAG": "2023762157",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
BACKGROUND AND STUDY AIM
To minimize bile leakage and avoid possible death because of stent migration in endoscopic ultrasound-guided hepaticogastrostomy (EUS-HGS), we have recently combined EUS-HGS with EUS-guided antegrade stenting (EUS-AS) of the biliary obstruction using a novel uncovered metallic stent with a fine-gauge delivery system. In this pilot study, we evaluated the feasibility and adverse events associated with this combination therapy using the novel stent.
PATIENTS AND METHODS
We performed EUS-guided antegrade stenting and hepaticogastrostomy in 12 consecutive patients.
RESULTS
The novel EUS-AS stent was placed across the ampulla of Vater in 8 patients and above the ampulla in 4. Technical and functional success rates were 100 %. In addition, the insertion of the first stent was achieved in all patients without dilation of the fistula between stomach and intrahepatic bile duct. Although 1 patient experienced mild pancreatitis, adverse events such as bile peritonitis or stent dysfunction did not occur during follow-up (mean 122 days, range 62 - 210 days).
CONCLUSION
This method appears to safely and effectively avoid adverse events associated with EUS-HGS.
|
2022-12-03T13:16:04.378Z
|
211,087,294 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1073/pnas.1913810117",
"MAG": "3006590330",
"PubMedCentral": "7049113"
},
"license": "CCBY",
"status": "HYBRID",
"url": "https://www.pnas.org/content/pnas/117/8/4320.full.pdf"
}
|
Significance CLL is characterized by autonomous B cell receptor (BCR) signaling. CLL subsets are empirically defined by sequence similarities of the BCR heavy chain. However, in the unfavorable subset 2, an acquired mutation (termed R110) in the light chain stimulates autonomous BCR signaling. This study demonstrates that the oncogenic R110 mutation dictates the unfavorable prognosis and is not restricted to the conventional subset 2. Interestingly, carriers of a particular light-chain allele (IGLV3-21*01) are predisposed to develop CLL because this allele enables autonomous BCR signaling by R110 as a single-point mutation. Monoclonal antibodies permit convenient screening for R110-expressing CLL, showing that it is the largest immunologically defined CLL subset and an example of functional rather than empirical CLL subclassification. The prognosis of chronic lymphocytic leukemia (CLL) depends on different markers, including cytogenetic aberrations, oncogenic mutations, and mutational status of the immunoglobulin (Ig) heavy-chain variable (IGHV) gene. The number of IGHV mutations distinguishes mutated (M) CLL with a markedly superior prognosis from unmutated (UM) CLL cases. In addition, B cell antigen receptor (BCR) stereotypes as defined by IGHV usage and complementarity-determining regions (CDRs) classify ∼30% of CLL cases into prognostically important subsets. Subset 2 expresses a BCR with the combination of IGHV3-21–derived heavy chains (HCs) with IGLV3-21–derived light chains (LCs), and is associated with an unfavorable prognosis. Importantly, the subset 2 LC carries a single-point mutation, termed R110, at the junction between the variable and constant LC regions. By analyzing 4 independent clinical cohorts through BCR sequencing and by immunophenotyping with antibodies specifically recognizing wild-type IGLV3-21 and R110-mutated IGLV3-21 (IGLV3-21R110), we show that IGLV3-21R110–expressing CLL represents a distinct subset with poor prognosis independent of IGHV mutations. Compared with other alleles, only IGLV3-21*01 facilitates effective homotypic BCR–BCR interaction that results in autonomous, oncogenic BCR signaling after acquiring R110 as a single-point mutation. Presumably, this mutation acts as a standalone driver that transforms IGLV3-21*01–expressing B cells to develop CLL. Thus, we propose to expand the conventional definition of CLL subset 2 to subset 2L by including all IGLV3-21R110–expressing CLL cases regardless of IGHV mutational status. Moreover, the generation of monoclonal antibodies recognizing IGLV3-21 or mutated IGLV3-21R110 facilitates the recognition of B cells carrying this mutation in CLL patients or healthy donors.
|
2022-12-10T04:49:14.791Z
|
10,491,111 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3354/DAO074049",
"MAG": "2073489558",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Calcein marking and cohabitation challenges have not been investigated in fish parasite research. This study evaluated a cohabitation challenge method in immunization trials against Ichthyophthirius multifiliis (Ich) using calcein, a fluorescent dye, to mark channel catfish Ictalurus punctatus (Rafinesque). Fish were marked by calcein immersion at 0, 500, and 1500 mg l(-1), and then challenged with 15 000 theronts fish(-1). No difference was noted in fish infection levels, mortality, and mean days to death (MDD) caused by Ich between unmarked and marked fish or between fish marked with high (1500 mg l(-1)) and low (500 mg l(-1)) concentrations of calcein. After ensuring that calcein marking had no effect on the susceptibility of fish to Ich theronts, 2 immunization trials were conducted to evaluate the cohabitation challenge model using calcein-marked catfish. Fish mortality, relative percent survival (RPS), and MDD were compared between cohabitation-challenged fish and fish challenged by non-cohabitation. No significant difference was observed in RPS for cohabitation-challenged fish and fish challenged by non-cohabitation. A cohabitation challenge can be used as an alternative challenge method in parasite studies, since it closely mimics natural exposure.
|
2022-12-18T23:18:42.734Z
|
118,982,156 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5000/EESK.2007.11.6.053",
"MAG": "234540496",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This study investigates the effect of site class, post-yield stiffness ratio, damping ratio, yield-strength reduction factor, and natural period on inelastic displacement ratio of bilinear SDF systems located at the sites classified as NEHRP site class B,C,D. The previous studies developed inelastic displacement ratio using equal displacement rule in the intermediate and long period range. But, this approximation overestimates the inelastic displacement ratio. Furthermore, inelastic displacement ratio has not been developed for the systems having a damping ratio less than 5%. This study conducts nonlinear regression analysis for proposing equations for calculating median and deviation of the inelastic displacement ratio of the bilinear SDOF system having damping ratios ranging from 0 to 20%. Using median and deviation of the inelastic displacement ratio, probabilistic inelastic displacement ratio is estimated, which can be used for performance-based seismic evaluation.
|
2022-05-13T00:39:58.127Z
|
95,212,448 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1252/JCEJ.36.1152",
"MAG": "1994180912",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
By using a Lab-scale Expanded Granular Sludge Bed (EGSB) reactor, the strategies of start-up and the changes of characteristics of granular sludge before and after start-up were investigated. In the first stage, the pentachlorophenol (PCP) concentration in wastewater was fixed at 5 mg/L, and the organic loading rate (OLR) gradually increased. The OLR increased to 5.4 kg COD/(m 3 -reactor d) after 25 days. Then began the second stage, OLR was stabilized as 5 kg COD/(m'-reactor d), while the PCP concentration was gradually increased. The PCP loading rate increased to 94.7 mg/(L-reactor d) in 63 days after the second stage start-up, the COD removal and PCP removal were 91.2% and 99.6% respectively. The EGSB reactor has the ability to bear PCP overloading to some extent. After the start-up was finished, the settlement velocity of granular sludge increased, the specific methanogenic activity of sludge and dechlorination rate of PCP were apparently increased. The results show that the two-stage start-up strategy is appropriate.
|
2022-08-25T09:54:18.140Z
|
28,421,162 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1346-8138.2005.tb00731.x",
"MAG": "2068874230",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Lymphomatoid papulosis (LyP) is a rare skin disease with a benign course but a malignant histologic appearance based on atypical lymphocytes. Waldenström's macroglobulinemia (WM) is a diffuse infiltration of the bone marrow by cells that synthesize IgM immunoglobulins. A 46‐year‐old female presented with a two year history of weakness, fatigue, anemia, and recurring multiple erythematous papules and nodules in the skin. The skin biopsy showed pleomorphic lymphoid cells with atypical mitoses permeated by a diffuse dermal infiltrate of normal appearing lymphocytes. The neoplastic cells were positive for CD30, CD3, and CD5 but negative for CD20 and EMA. The bone marrow was hypercellular due to a diffuse infiltration by lymphocytes, plasma cells, and plasmacytoid lymphocytes. LyP is a lymphoproliferative disorder of CD30‐positive T cells that may be associated with other lymphoid malignancies, particularly Hodgkin's disease, mycosis fungoides, and anaplastic T cell lymphomas. To our knowledge, this is the first report of a LyP appearing in a patient with WM.
|
2022-08-31T13:55:04.753Z
|
146,142,341 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/01440365.2015.1088371",
"MAG": "2181799248",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The trust is today an international legal institution, firmly established in jurisdictions all over the world, including those in Asia. The process by which the trust and trust law were transplanted in Asia forms a rich tapestry of complex themes. A key development was the codification of trust law by the colonial government of India at the end of the nineteenth century. This embraced an ‘obligational’ model of the trust that removed the notion of ‘equitable ownership’. On the face of it, the Indian Trusts Act 1882 carried innovations in both form and substance. Although a closer examination reveals limits in the innovations, the Act proved influential in the failed attempts to codify the law in England and the transplantation of trust law into the mixed legal system of Ceylon and the civilian system of Japan. The historical analysis of these developments sheds light on modern debates about the transplantation of law in general, the comparative study of trust law and theoretical discussions about the nature of the trust.
|
2022-09-08T07:40:59.642Z
|
46,500,760 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.26719/2010.16.4.402",
"MAG": "1755147223",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://doi.org/10.26719/2010.16.4.402"
}
|
This study assessed the knowledge and practices about folic acid in pregnancy among pregnant women attending 2 main maternal and child health centres in Abu Dhabi. The majority of the 277 interviewed mothers (79.1%) had heard of folic acid and 46.6% had accurate knowledge about the role of folate in preventing neural tube defects. There were good practices regarding folate supplementation in the current pregnancy; most of the interviewed mothers took it daily and in the recommended dose. However, only a minority took it prior to pregnancy. Education, irrespective of age or parity, was the major factor determining better knowledge of folic acid in pregnancy.
|
2022-12-09T18:54:11.780Z
|
31,390,559 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2147/CIA.S142102",
"MAG": "2768779638",
"PubMedCentral": "5713704"
},
"license": null,
"status": null,
"url": null
}
|
Objective The primary objective of this study was to evaluate whether the polymorphism of poly (ADP-ribose) polymerase-1 (PARP-1) is involved as a potential risk factor in the development of acute renal injury in elderly Chinese patients with diabetes mellitus. Subjects and methods In this pilot study, diabetic patients of either gender (aged ≥65 years) with a confirmed diagnosis of acute renal injury and individuals with no clinical symptoms of acute renal injury were enrolled at Nanxishan Hospital of Guangxi Zhuang Autonomous Region, China. Genetic polymorphism of PARP-1 was assessed using polymerase chain reaction-restriction fragment length polymorphism assay. Cytokine levels (interleukin [IL]-6, IL-1β and tumor necrosis factor-alpha) were measured in the serum samples by sandwich enzyme-linked immunosorbent assay technique. Results A total of 130 Chinese patients with acute renal injury and 130 Chinese individuals with no clinical symptoms of acute renal injury were included. We found that the patients with GG genotype and carriers of the G and C alleles of PARP-1 were at high risk of developing acute renal injury. Moreover, del/ins polymorphism of the NF-κB1 gene was also found to be associated with acute renal injury. In addition, the levels of IL-6, IL-1β and tumor necrosis factor-alpha were significantly increased in patients with acute renal injury (p<0.05). Conclusion Our findings showed the involvement of PARP-1 polymorphisms in the development of acute renal injury in Chinese individuals. This study identified the involvement of two SNPs of PARP-1 (C410T and G1672A) in development of acute renal injury among Chinese diabetic patients. Also, increased expression of C and G alleles of PARP-1 can be considered as one of the potential risk factors for developing acute renal injury. Increased serum cytokine levels can be considered as one of the potential risk factors for developing acute renal injury.
|
2022-12-10T21:23:07.349Z
|
40,943,020 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/hmg/4.12.2233",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The von Hippel-Lindau disease (VHL) gene is a putative tumor suppressor gene responsible for VHL, an autosomal dominantly inherited multitumor syndrome. It is also implicated in the development of sporadic tumors including clear cell renal carcinoma and central nervous system hemangioblastoma. To define the molecular basis of VHL patients in Japanese populations, we tested for germline mutations of the VHL gene in 45 unrelated Japanese VHL patients by single-strand conformation polymorphism (SSCP) analysis and Southern blot analysis. We detected 23 (51%) intragenic mutations and three (6.7%) deletions by SSCP analysis and Southern blot respectively. The intragenic mutations consisted of 14 missense mutations, seven microdeletions or insertions and two splice-site mutations. Interestingly, nine of 10 mutations in exon 1 are localized in a short region of 37 nucleotides. Five unique sites of mutation were included, which were not seen in previous studies. Unlike Western VHL patients, nonsense mutations were not found in Japanese VHL patients. If the presence of pheochromocytomas is regarded as phenotypic marker for VHl classification, the mutations found in 22 VHL patients without pheochromocytoma consisted of 11 missense mutations, six microdeletions or insertions, two splice-site alterations and three deletions. The mutations found in four VHL patients with pheochromocytomas consisted of one missense mutation at nucleotide 683 (codon 228), two missense mutations at nucleotide 712 (codon 238) and a novel 20 bp insertion at nucleotide 776 (codon 259). Although the mutations at codon 238 are the mutational hot spot found in Western VHL patients with pheochromocytomas, a 20 bp insertion of original VHL cDNA sequence, from nucleotide 777 to 796, is a unique mutation. Our results suggest that mutations in Japanese VHL patients contain some unique features compared with those in Western patients. VHL gene has a critical role for the etiology in VHL in Japanese populations as well as Western VHL.
|
2022-12-12T01:22:31.144Z
|
84,262,512 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.2478/v10245-011-0012-7",
"MAG": "2007019879",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://www.sciendo.com/pdf/10.2478/v10245-011-0012-7"
}
|
Abstract Field studies were conducted in the years 2003-2005 in the Experimental Farm of the University of Life Sciences in Lublin. Beans from four cultivars - ‘Paulista’ and ‘Hit’ (green pods) and ‘Korona’ and ‘Galopka’ (yellow pods) - were grown on fawn soil, formed of loess deposits, on chalky marls, containing 1.4% organic substances on average. There were six sowing terms, every 6-7 days starting from the middle of May to the end of June. French bean harvest was performed once, when about 75% of the pods on the plants were in the phase of technological maturity, which fell between the third ten days of July and the first ten days of September. From the plot and plant the number and yield of the pods were determined: total, marketable and non-marketable small pods, unshapely and overripe pods, as well as those with symptoms of disease. The highest total and marketable pod yields - on average, 15.45 and 11.06 t ha-1, respectively - were obtained from plants sown in the first ten days of June, whereas the lowest - 12.54 and 9.54 t ha-1 - were from those sown in the middle of May. As a result of performing a one-time French bean pod harvest, the share of non-marketable pod yield in the total yield was on a similar level (24-28%), depending on the growing term. Variability was demonstrated in the share of particular non-marketable yield fractions (small pods, undersized, unshapely, and overripe pods, as well as those with disease symptoms), depending on the sowing date. Growing four French bean cultivars from sowing in the period from the middle of May to the end of June allowed us to extend the period of fresh pod harvest to six or seven weeks.
|
2022-12-17T22:20:29.844Z
|
9,133,765 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/TPWRD.2016.2574924",
"MAG": "2471698213",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper compares different methods for voltage-dip characterization. Those methods are based on earlier proposed algorithms for extracting three-phase characteristics (dip type, characteristic voltage, and so-called “PN factor”). The difference between the 12 methods being studied in this paper is in the way in which the time variation of those characteristics is treated to result in single-event characteristics. The methods are applied to 259 measured voltage dips, and the performance of the different methods is compared. It is found that small differences in the method can result in big differences in results. From the comparison, two methods are selected and recommended for inclusion in international standards.
|
2022-12-19T18:54:57.673Z
|
235,553,288 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1049/HVE2.12106",
"MAG": "3159145206",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
An investigation is made of the influence of an accumulated charge sprinkled on the surface of an epoxy resin plate in corona mode on partial discharge inception and its forms as analyzed by optical imaging at DC voltage. The effects of the polarities of both the deposited hetero ‐ and homocharges were investigated. The occurrence of first streamer discharges was detected electrically and observed by optical imaging. The various forms of streamers were acquired by optical imaging and associated with the polarity and intensity of the accumulated surface charges. Surface charge sprinkling on the epoxy specimen surface was quantitatively evaluated by surface charge mapping. In addition, the effect of the subsequent discharges occurring in a heterocharge configuration above the inception voltage was observed. In terms of their directions and lengths, the kinetics of the streamer filaments revealed a strong dependence on both the polarity and the intensity of an accumulated charge. Compared with the reference charge ‐ free surface, the strongest drop in dielectric strength in the interelectrode space with a sprinkled charge was obtained for the heterocharge configuration. The presented results provide a contribution to the assessment of streamer behaviour in the presence of accumulated surface charges, including its polarity and intensity.
|
2022-12-19T03:08:16.178Z
|
210,498,362 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/0142723719885270",
"MAG": "2987911357",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://journals.sagepub.com/doi/pdf/10.1177/0142723719885270"
}
|
The present study investigated whether Mandarin-speaking preschool children with autism spectrum disorders (ASD) were able to use prosodic cues to understand others’ communicative intentions. Using the visual world eye-tracking paradigm, the study found that unlike typically developing (TD) 4-year-olds, both 4-year-olds with ASD and 5-year-olds with ASD exhibited an eye gaze pattern that reflected their inability to use prosodic cues to infer the intended meaning of the speaker. Their performance was relatively independent of their verbal IQ and mean length of utterance. In addition, the findings also show that there was no development in this ability from 4 years of age to 5 years of age. The findings indicate that Mandarin-speaking preschool children with ASD exhibit a deficit in using prosodic cues to understand the communicative intentions of the speaker, and this ability might be inherently impaired in ASD.
|
2022-12-29T18:34:38.590Z
|
136,445,060 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1117/12.2284766",
"MAG": "2739629954",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Human skin surface has unevennesses called sulcus cutis and crista cutis. It is known that these affect the light propagation in human skin. In this study, we made a prototype of skin tissue phantom and investigated its spectral properties and problems to be solved.
|
2022-01-27T09:22:41.711Z
|
239,241,249 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.17161/kjm.vol14.15774",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "HYBRID",
"url": "https://journals.ku.edu/kjm/article/download/15774/14151"
}
|
We read with deep attention the case report recently published about the peculiar association of morphea, celiac disease, dermatitis herpetiformis and dermatomyositis , and we would discuss the particular genetics that lay behind morphea and related autoimmune disorders, with a focus on HLA genes.
|
2022-01-24T19:18:06.186Z
|
119,945,368 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1117/12.327985",
"MAG": "1971642530",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We describe the design and operation of a high speed optical tomography system for measuring 2D images of a dynamic phase object at a rate of 5 kHz. Data from a set of eight Hartmann wavefront sensors is back-projected to produce phase images showing the details of the inner structure of a heated air flow. Series of reconstructions at different downstream locations illustrate the development of flow structure and the effect of acoustic flow forcing.
|
2022-02-09T22:33:48.676Z
|
7,056,912 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CRMICO.2010.5632551",
"MAG": "2052267902",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A systematical approach to formation of cell libraries (PDKs) of MMIC is presented. Also, a procedure allowing automatic MMIC layout generation for specified foundry process is developed in Microwave Office (MWO) CAD tool. These results are used in developing of a pilot version of PDK for 0.15 μm pHEMT/mHEMT GaAs process.
|
2022-02-13T09:24:51.927Z
|
249,491,163 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.51202/0947-7527-2022-21-038-1",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Drogeriemärkte sind vom Umsatz wieder nahezu auf Vor-Corona-Niveau. In der jüngsten Vertriebslinienbetrachtung von Information Resources (IRI) haben auch Discounter Boden gut gemacht.
|
2022-06-10T15:39:19.554Z
|
93,521,837 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1524/zkri.2000.215.12.757",
"MAG": "1973453559",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Crystal data and results of structure refinement using powder X-ray diffraction and Rietveld analysis for armstrongite, CaZr[Si6O15]·3H2O, are reported. Experimental data were collected using MoKα1 radiation over the range 2° - 51.98° 2θ. Armstrongite is monoclinic (space group C2, Z = 4), with a = 14.018(1) Å, b = 14.133(1) Å, c = 7.840(1) Å, β = 109.40(1)°. The crystal structure, reported by Kashaev and Sapozhnikov (1978) has been refined by Rietveld analysis, resulting in Rwp = 2.75. The structure is based on a heterogeneous octahedra-tetrahedra framework (ZrSi6O15) built by corrugated silicate sheets connected by ZrO6 octahedra. The seven-fold Ca polyhedron contains 2 H2O molecules. Two new sites for H2O molecules on the 2-fold axis in the voids of the zeolite like framework allowed to achieve the complete correspondence between chemical and structural data.
|
2022-07-15T03:48:52.136Z
|
53,086,045 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.11604/pamj.2018.30.101.11593",
"MAG": "2777517404",
"PubMedCentral": "6195242"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://doi.org/10.11604/pamj.2018.30.101.11593"
}
|
This work aims at enhancing the management of childhood asthma, with a focus on pharmacists in particular, by evaluating their knowledge of childhood asthma and assessing their attitude while they are providing asthma medicines. Consequently, it will look at the necessity of introducing training days about childhood asthma for pharmacists. This is a transversal and descriptive study which lingered from August to October 2015. Data has been collected using a questionnaire that was self-administered to every surveyed pharmacist in the city of Rabat. The 104 pharmacists who replied to the questionnaire have an average general understanding about asthma and its treatment. Only a quarter of them managed an asthma crisis in their pharmacy before directing the child to the emergency. 50% of them do not know the difference between the basic asthma therapy and the asthma attack therapy. However, all of them recommended the parents to see a physician regarding their child’s asthma. 75% advise the systematic use of an asthma spacer with the inhaler. 87.5% of them give advice to parents regarding the good measures for environmental control, and 98% estimate that the therapeutic education is important in childhood asthma management. 88.5% among them are interested in training days about childhood asthma.This study shows the necessity of further pharmacists’ education about asthma and its management.
|
2022-12-16T21:06:36.897Z
|
122,752,785 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1063/1.1380220",
"MAG": "2095255507",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The interface between the inorganic semiconductor p-type InP and the conjugated polymer poly(pyrrole) exhibits the electrical characteristics of a Schottky diode. Capacitance–voltage measurements yield an average barrier height of 0.62 ± 0.01 eV at temperature T =298 K. At the same temperature, the empirical quality factor, extracted from current–voltage measurements, is near unity. However, the current–voltage measurements show a deviation from thermionic emission theory as the temperature is reduced, as witnessed by the increase of the quality factor and the curvature in the Richardson plot. Such deviation is best explained by the barrier inhomogeneity model, in which the barrier becomes voltage dependent due to the interaction of a small low-barrier region with a higher surrounding potential, termed the “pinch-off” effect. Traditional current–voltage models, including image force lowering or an interfacial layer, cannot predict the temperature dependence of the current–voltage data, although thermionic...
|
2022-12-20T05:21:14.515Z
|
197,481,379 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.32832/JM-UIKA.V6I1.21",
"MAG": "2952177863",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The results showed that : 1 ) The regression coefficient was significant to the outcome of t -1.509 0.05 means the raw materials policy regression equation (X1) of the finished product Gum Rosin and Turpentine (Y) declared not significant, 2) Value of the coefficient for the variable engine optimization (X2) to the value of b2 = 0.878 in the multiple linear regression equation Y = a + b1X1 + b2 = 0.878 b2X2 so that means every increase of 1 point of the optimization of the engine it will affect the finished product gondorukem and turpentine on Perhutanioffice West Java Regional Division by 0.878 points and the other independent variables constant, 3) Material relationship with the optimization engine in Java Regional Division Perhutanioffice Baratmenunjukan kelinearan a very strong relationship between raw materials (X1) with engine optimization (X2), 4) Raw materials and optimization engine gondorukem effect on the finished product and turpentine. Percentage of raw material variables influence the optimization engine and machine jointly obtained value of R Square of 1.000 or (100 %). This shows that the percentage contribution of independent variables , namely raw materials and the optimization of the engine together against Gum Rosin and Turpentine finished product at 100%.
|
2022-02-08T06:35:07.348Z
|
242,432,855 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21203/rs.3.rs-952070/v1",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GREEN",
"url": "https://www.researchsquare.com/article/rs-952070/latest.pdf"
}
|
Cognitive impairment and dementia are conventionally categorised according to their causative disease, such as Alzheimer's disease and cerebrovascular disease. Cognitive impairments of different aetiologies often share pathological cerebral blood circulation patterns, characterised by perfusion and resistance. Here, we show that these two features are associated with distinct types of cognitive impairment. Using carotid ultrasonography, we evaluated the circulation status of individuals with little to no subjective cognitive symptoms. We assessed individuals’ cognitive status using the Frontal Assessment Battery for executive function and Mini-Mental State Examination for learning and memory. Regression analysis showed that the hyper-resistance and hypo-perfusion components predicted the Frontal Assessment Battery and Mini Mental State Examination scores, respectively. These results are consistent with previous findings of hyper-resistance being associated with atherosclerosis, which disproportionately affects the frontal lobe and contributes to executive function impairments; meanwhile, hypo-perfusion disproportionately affects temporal lobe functions associated with learning and memory. We propose a novel concept that cognitive impairments fall into two subtypes regardless of the brain disease: hyper-resistance and hypo-perfusion subtypes. As these subtypes can be measured noninvasively and are treatable, this distinction would help design preventive and therapeutic strategies for dementia.
|
2022-07-31T20:12:53.805Z
|
21,416,721 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/000306516401200401",
"MAG": "2094638500",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
NY DISCUSSION of psychoanalytic methodology invites a wide range of considerations. These vary from a discussion of A theoretical conceptual issues involved in the nature of the relationship among the data, the method, and the theory of psychoanalysis to a discussion of empirical research issues involved in the advancement of systematic knowledge in our field in a manner that is simultaneously loyal, both to the demands for rigor and objectivity in science, and to the complexity and subtlety of the clinical processes under scrutiny. The creation and carrying out of a clinical research into the effectiveness of therapy and the mutative factors in the therapeutic process such as the Psychotherapy Research Project a t The Menninger Foundation necessarily involve one in detailed consideration of just this very same range of issues, from conceptual to empirical, among them the place of prediction (and postdiction) in hypothesis building and validating, the problem of the kind and level of quantification appropriate to the study of qualitative clinical data, the intrusion of value commitments into the empirical assessment of therapeutic change and improvement, the concept of naturalistic research study and the alteration of the natural data by the intrusion of
|
2022-09-14T17:13:51.017Z
|
144,716,617 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1353/jsm.2013.0013",
"MAG": "2024199269",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://muse.jhu.edu/article/523033/pdf"
}
|
Fantasy sport is an online sport activity utilizing sport communication outlets in multiple ways. With nearly 35 million fantasy sport participants, many sport media companies such as ESPN, CBS Sports, and Yahoo! Sports have strengthened their online presence by creating and hosting fantasy sport Web sites. Fantasy sport is developed, controlled, and consumed primarily online and uses Web-based programs created by companies to host game and league-style competition. Fantasy sport utilizes player information and statistics from actual competition. Since the concept of fantasy sport is based around this type information, it utilizes several communication outlets to assist in the overall experience. Any person involved in fantasy sport can seek out information from a newspaper, magazine, radio, television, or the Web. The purpose of this study is to identify in what ways fantasy sport host sites and traditional communication outlets are meeting the informational needs of the fantasy sport user. Data were collected through the use of an open-ended questionnaire completed by fantasy sport users. The results of this study indicate a majority veering away from their fantasy sport host site and using the Web as a means to gather news, player information, statistics, and expert advice. They also use television as a way to watch, listen, or seek information from game broadcasts. Reasons for not using a particular communication outlet range from issues of access, desire to use, cost, and choice of another outlet.
|
2022-10-23T13:57:01.708Z
|
46,252,944 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/00007435-198804000-00009",
"MAG": "2075777376",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://journals.lww.com/stdjournal/Citation/1988/04000/Lower_Genital_Tract_Infections_in_Women_.9.aspx"
}
|
We screened 392 women attending the Laboratory of Microbiology of Toulouse Purpan Hospital for symptoms of lower genital tract infection for six microorganisms. Rates of isolation of Neisseria gonorrhoeae, Chlamydia trachomatis, Candida albicans, Mycoplasma hominis, and Gardnerella vaginalis were 1%, 7.7%, 29.8%, 23.8%, and 37.5%, respectively. Trichomonas vaginalis was detected by direct examination in specimens from 3.1% of patients. Another goal of this study was to determine the relative prevalence of these microorganisms in relation to clinical and epidemiologic findings. C. trachomatis was isolated significantly more often from patients under 25 year old (P less than 0.001), from those who use oral contraceptives (P less than 0.01), from those who have a male sexual partner with symptoms of sexually transmitted disease (P less than 0.001), and from those who present signs of cervicitis (P less than 0.05). Isolation of C. albicans was significantly associated with vulvar pruritus (P less than 0.01), vulvitis (P less than 0.01), and vaginitis (P less than 0.001). G. vaginalis and M. hominis are significantly associated with bacterial vaginosis (P less than 0.001). This syndrome was diagnosed clinically in 27.2% of our study population and was highly correlated with use of an intrauterine device (P less than 0.05).
|
2022-10-07T00:15:37.273Z
|
237,363,913 |
{
"externalids": {
"ACL": null,
"ArXiv": "2108.13554",
"DOI": "10.3389/fphy.2021.773128",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.frontiersin.org/articles/10.3389/fphy.2021.773128/pdf"
}
|
In order to model and evaluate large-scale quantum systems, e.g., quantum computer and quantum annealer, it is necessary to quantify the “quantumness” of such systems. In this paper, we discuss the dimensionless combinations of basic parameters of large, partially quantum coherent systems, which could be used to characterize their degree of quantumness. Based on analytical and numerical calculations, we suggest one such number for a system of qubits undergoing adiabatic evolution, i.e., the accessibility index. Applying it to the case of D-Wave One superconducting quantum annealing device, we find that its operation as described falls well within the quantum domain.
|
2022-10-18T08:00:37.584Z
|
30,706,452 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1364/AOE.2008.SUC4",
"MAG": "2118807852",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A long period grating is eroded. Experimental results show that resonant wavelength shift of can be enhanced by choosing thinner cladding radius and higher order cladding mode. Analysis is given to explain the principle.
|
2022-12-19T14:27:40.462Z
|
135,856,520 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4028/www.scientific.net/AMR.47-50.355",
"MAG": "2062129756",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A simple catalytic combustion technique for synthesizing bamboo-like carbon was presented. Ethanol was used as carbon source and fuel, copper plate as substrate, and iron salt as catalyst precursors. The as-grown black powder was characterized by means of scanning electron microscopy, and transmission electron microscopy. The results show that the morphology and microstructure of bamboo-like carbon nanotubes are affected by novel synthesis conditions, such as concentration of catalyst precursor solution, synthesis time, flame perturbations, and synthesis temperature etc.. According to observations and analysis of experimental results, a possible growth mechanism of bamboo-like carbon nanotubes is proposed and discussed.
|
2022-02-09T11:26:51.740Z
|
2,932,563 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/MTV.2004.16",
"MAG": "1575345240",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We present a tool and a methodology for micro-architecture verification of microprocessors. This document serves as an introduction to the invited talk in the special session on micro-architecture verification of microprocessors.
|
2022-02-13T13:08:57.805Z
|
49,304,000 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1145/3177457.3177480",
"MAG": "2807988987",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We present a new method, symbolic backward simulation, for detecting bugs in Java bytecode programs. In order to find bugs comprehensively, the method determines conditions on the input side by tracing back from the tail of the program while performing reverse execution for each bytecode. Generally, reverse execution is difficult, especially for instructions of two-input-one-output operations and branches. Our method solves the problem symbolically with essentially fewer simulation cases than numerical testing and forward symbolic analysis. We also show simulation results which detected a branch condition error and a real number processing error.
|
2022-09-21T13:30:52.968Z
|
247,289,186 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.7759/cureus.22857",
"MAG": null,
"PubMedCentral": "8982499"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.cureus.com/articles/84122-efficacy-of-topical-silver-nitrate-for-control-of-post-tonsillectomy-hemorrhage.pdf"
}
|
Objective Management of patients with post-tonsillectomy hemorrhage (PTH) is not well defined but may include observation, topical bedside treatments, or return to the operating room. Data on the use and efficacy of silver nitrate as a topical bedside agent for the management of PTH remain unexplored. Our primary objective was to assess the efficacy of silver nitrate in reducing the need for operative control of PTH. Methods Single-institution retrospective chart review included patients aged 5-18 years who presented with tonsillar bleeding within 30 days of tonsillectomy. Patients undergoing observation or bedside silver nitrate cautery were compared based on clinical characteristics and experience of the physician performing the procedure. The outcome of interest was rebleeding requiring operative control. Sample characteristics according to treatment modality were described using Fisher’s exact tests and ANOVA. Results Of the patients eligible for inclusion, 29 (20%) were observed and 70 (48.3%) were treated with topical silver nitrate. Age was the only statistically significant clinical difference among treatment groups. The silver nitrate group had more patients who underwent operative control of PTH compared to the observation group (p = 0.004). When comparing the need for operative control between the observation group and patients who had initial success with silver nitrate, there was no difference (p = 0.29). No differences were found in the rate of bleeding requiring operative control when comparing experience of the physician performing the procedure (p = 0.20). Conclusion More patients who underwent silver nitrate cautery required PTH control in the operating room compared to the observation group. This may be due to patient selection as our results also suggest that there is no statistical difference in rates of operative control of PTH when comparing initial successful treatment with topical silver nitrate to observation. Age is likely a factor that was used by physicians in this study to decide the initial management of PTH. Provider experience does not appear to affect rebleeding rates. Future studies are necessary to evaluate the clinical impact of silver nitrate in the context of PTH and will benefit from more robust sample sizes and enhanced diversity in the sample group.
|
2022-05-13T00:45:36.961Z
|
86,848,385 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/fld.3774",
"MAG": "2149754180",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The benefits of unstructured grids in hydrodynamic models are well understood but in many cases lead to greater numerical diffusion compared with methods available on structured grids. The flexible nature of unstructured grids, however, allows for the orientation of the grid to align locally with the dominant flow direction and thus decrease numerical diffusion. We investigate the relationship between grid alignment and diffusive errors in the context of scalar transport in a triangular, unstructured, 3‐D hydrodynamic code. Analytical results are presented for the 2‐D anisotropic numerical diffusion tensor and verified against idealized simulations. Results from two physically realistic estuarine simulations, differing only in grid alignment, show significant changes in gradients of salinity. Changes in scalar gradients are reflective of reduced numerical diffusion interacting with the complex 3‐D structure of the transporting flow. We also describe a method for utilizing flow fields from an unaligned grid to generate a flow‐aligned grid with minimal supervision. Copyright © 2013 John Wiley & Sons, Ltd.
|
2022-10-27T21:03:53.207Z
|
122,031,388 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/MWSCAS.1994.518941",
"MAG": "2139148411",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The ways of generation of forward and inverse transformation kernels for recently introduced generalized Walsh transform in Hadamard ordering have been presented. Algorithms that generate Hadamard ordered forward and inverse generalized Walsh transforms for an arbitrary polarity have been introduced. Mutual transitions and flow diagrams for the calculation of generalized Walsh spectra in different polarities from known spectrum of an arbitrary polarity for both forward and inverse transforms have been given.
|
2022-11-05T13:21:15.030Z
|
25,914,059 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1182/BLOOD.V87.12.5213.BLOODJOURNAL87125213",
"MAG": "190597540",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
One hundred and forty-three patients with p210 BCR-ABL-positive leukemia were studied for coexpression of p190 BCR-ABL mRNA. p190 mRNA was detected in 14 of 16 (88%) patients with chronic-phase chronic myeloid leukemia (CML) at diagnosis, in 10 of 10 (100%) CML patients in blast crisis, in 75 of 107 (70%) CML patients receiving interferon-alpha (IFN-alpha), and 10 of 10 (100%) patients with p210 BCR-ABL-positive acute lymphoblastic leukemia (ALL). Neither p210 nor p190 BCR-ABL transcripts were detected in normal healthy adults (n = 20). The numbers of p190 transcripts determined by competitive PCR in patients with CML were low compared with the numbers of p210 transcripts. The median numbers of p210 and p190 transcripts per unit volume of cDNA in positive samples were 1.0 x 10(5) (range, 15 to 1.4 x 10(6)) and 10 (range, 10 to 2.9 x 10(3)), respectively. The numbers of p190 and p210 transcripts were significantly correlated in individual samples (r = .65, P < .001). The median number of p210 BCR-ABL transcripts was significantly lower in samples negative for p190 BCR-ABL transcripts than in samples in which p190 BCR-ABL transcripts were identified (3.1 x 10(3)[n = 73] v 1.0 x 10(5)[n = 115]; P < .0001). The median ratio of p190 to p210 BCR-ABL mRNA was not significantly different between chronic phase CML (1.9 x 10(-4)) and CML in blast crisis (1.7 x 10(-4)). The median ratio in p210 ALL was also low (1.9 x 10(-3)) but significantly higher than that of CML. We conclude that pl90 BCR-ABL transcripts are frequently present at a low level in p210 BCR-ABL-positive leukemias. p190 mRNA may arise through alternative or missplicing and its presence is probably of no pathogenetic significance.
|
2022-12-21T07:23:31.726Z
|
254,433,498 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.36233/0372-9311-330",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://microbiol.crie.ru/jour/article/download/1276/782"
}
|
Background. Children and adolescents with infection caused by the hepatitis C virus (HCV) have not been given sufficient attention due to mild forms of HCV and delays in approval of antiviral treatment regimens. Omissions in the studies of pediatric cohorts and shortcomings of management policies aimed at children should be eliminated by improving screening coverage and access to treatment.
The aim of the study was to present the results of the cascade sequence of diagnostic testing, care and treatment of children with HCV in the Moscow Region (MR).
Materials and methods. The study included all HCV seropositive children of MR (n = 175), who underwent screening tests, and it did not include patients living with HIV/HCV coinfection. Children were observed from 2017 to 2022. The HCV RNA was detected in 164 children and HCV genotypes were identified in 99 children. The stage of liver fibrosis was assessed in 73 children by transient elastography and by FIB-4 index calculation.
Results. In MR, 93.7% of seropositive children were tested for HCV RNA; 71.2% of adolescents over 12 years of age received treatment. The prevalence of HCV seropositivity was estimated at 0.113/1,000 children population; the prevalence of chronic HCV infection was at least 0.059/1,000. The dominant HCV subtypes were GT 1b (43.4% [the 95% confidence interval, 33.553.8%]), GT 3a (23.2% [15.332.8%]) and GT 3a/3b (20.2% [12.829.5%]). The incidence of viremic HCV infection per 100,000 children was 3.3 among children under 3 years of age; 7.0 among children aged 36 years; 7.7 among children aged 711 years, 4.4 among adolescents older than 12 years. Natural HCV clearance was reported at the frequency of 19.5% [13.826.4%]. Extrahepatic manifestations were of rare occasion 2.9% [0.96.5%]. Vertical transmission was the primary route of HCV transmission (78.3% [71.484.2%]); infection is assumed to occur during medical invasive procedures 7.4% [4.012.4%], drug using 0.6% [0.013.10%], in the family household 0.6% [0.013.10%]. New cases of HCV infection were more frequently detected during routine examination of children prior to hospitalization or children born to mothers with HCV. Viremic HCV was confirmed in 90.2% [84.694.3%], including HCV infection in 53.4% [45.061.6%], chronic liver disease in 35.8% [28.144.1%] having low activity and occasional consequences (the fibrosis METAVIR score of F1 and F1-2 17.8% [9.828.5%]). No significant clinical and epidemiological differences between the natural course of chronic HCV infection and the liver disease caused by HCV have been found. The burden of pediatric HCV in MR is aggravated by a significant proportion of socially vulnerable patients and patients with comorbid conditions.
Conclusion. One of the solutions for detection of new pediatric cases of HCV infection in MR can be offered by improvement of collaboration and continuity of care among healthcare organizations and early treatment of women of childbearing age. Further research is required to evaluate the effectiveness of routine testing of all socially vulnerable pediatric groups. Early application of pan-genotypic antiviral treatment regimens can contribute significantly to control of the HCV infection incidence in children.
|
2022-12-23T02:15:17.551Z
|
17,495,481 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/BMC.292",
"MAG": "2157430131",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
An ion-pair high performance liquid chromatographic method was developed for the simultaneous determination of p-aminosalicylic acid (PAS) and its degradation product m-aminophenol (MAP) in a newly developed multiparticular drug delivery system. Owing to the concentration differences of PAS and MAP, acetanilide and sulfanilic acid were used as internal standards, respectively. The separation was performed on a Chromolith SpeedROD RP-18e column, a new packing material consisting of monolithic rods of highly porous silica. The mobile phase composition was of 20 mm phosphate buffer, 20 mm tetrabutylammonium hydrogen sulphate and 16% (v/v) methanol adjusted to pH 6.8, at a flow-rate of 1.0 mL/min, resulting in a run-time of about 6 min. Detection was by UV at 233 nm. The method was validated and proved to be useful for stability testing of the new dosage form. Separation efficiency was compared between the new packing material Chromolith SpeedROD RP-18e and the conventional reversed-phase cartridge LiChroCART 125-4 (5 microm). A robustness test was carried out on both columns and different separation parameters (retention, resolution, run time, temperature) were determined.
|
2022-12-28T19:14:39.783Z
|
208,016,016 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.31449/inf.v43i3.2310",
"MAG": "2982863541",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.informatica.si/index.php/informatica/article/download/2310/1336"
}
|
Due to massive growth of Web information, handling useful information has become a challenging issue in now-a-days. In the past few decades, text summarization is considered as one of the solution to obtained relevant information from extensive collection of information. In this paper, a novel approach using modified shuffled frog leaping algorithm (MSFLA) to extract the important sentence from multiple documents is presented. The effectiveness of MSFLA algorithm for summarization model is evaluated by comparing the ROUGE score and statistical analysis of the model with respect to results of other summarization models. The models are demonstrated by the simulation results over DUC datasets. In the present work, it elucidates that MSFLA based model improves the results and find advisable solution for summary extraction
|
2022-02-08T03:55:57.173Z
|
250,648,348 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/i2ct54291.2022.9825305",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Request-response computing is a model of communications in which a client requests for service and the server responds with response. It is a model that is most widely used in modern day computing and is more reliable and resource aware. Security is a prime concern in this model of computing, where malicious entities may gain access to crucial data and resources illegitimately. An efficient authentication mechanism may establish a secure communication channel between client and server and avoid illegitimate access of resources. Here, we propose a two-phase authentication mechanism using address binding for securing the communications between clients and server. The first phase of binding is done using cryptographically generated address (CGA) and for the second phase, we have designed a novel Mathematically Generated Address (MGA), in which IPv6 address are masked using mathematical operations and it is lightweight and secure. The proposed mechanism is secure and efficient and is verified in security analysis and performance evaluation as well. The proposed mechanism is evaluated for security and performance and its analysis has found that the proposed mechanism works efficiently in terms of security and time in comparison to the existing mechanism.
|
2022-08-06T01:15:01.454Z
|
167,729,479 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1108/09576050110390211",
"MAG": "2043402393",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Current logistics systems are unable to react fast enough to rapidly changing environments, mainly because they are heavily focused on the goods handling processes. To compensate for this lack of flexibility, logistics services should be carried out by independently controlled logistics resources. But these resources together do have to guarantee the overall quality of services. Service‐controlled agile logistics solves the conflict that arises – independent resources working together – by strictly distinguishing between control and handling. It is based on control of logistics processes by the requested services themselves, which create their own “agents”, made responsible for realizing the service in the best possible way under changing circumstances. In order to examine the feasibility of this approach, a simulation program has been developed, and some preliminary results are presented.
|
2022-12-14T13:01:41.277Z
|
1,352,763 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1161/01.CIR.0000070020.79932.DB",
"MAG": "2141811337",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Background—Despite effective treatment with anticoagulants, 2% to 7% of patients with pulmonary embolism will die as a result of their disease. Methods and Results—We examined in 110 consecutive patients with pulmonary embolism whether plasma brain natriuretic peptide (BNP), a novel marker of (right) ventricular dysfunction, is a predictor of fatal pulmonary embolism. The relationship between BNP concentration measured at presentation and clinical outcome was assessed by comparing the proportion of outcome events among tertiles. Positive and negative predictive values of BNP levels in the highest and lowest tertiles were calculated. The risk of death related to pulmonary embolism if the BNP level is >21.7 pmol/L is 17% (95% CI, 6% to 33%). The negative predictive value for uneventful outcome of a BNP value <21.7 pmol/L is 99% (95% CI, 93% to 100%). Conclusion—This is the first study to show that plasma BNP levels seem to predict adverse outcome in patients with acute pulmonary embolism.
|
2022-12-21T05:26:14.958Z
|
1,162,060 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1162/089892904322984571",
"MAG": "2121273100",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "http://eprints.maynoothuniversity.ie/4866/1/PG_rTMS.pdf"
}
|
Repetitive transcranial magnetic stimulation (rTMS) offers a powerful new technique for investigating the distinct contributions of the cortical language areas. We have used this method to examine the role of the left inferior frontal gyrus (IFG) in phonological processing and verbal working memory. Functional neuroimaging studies have implicated the posterior part of the left IFG in both phonological decision making and subvocal rehearsal mechanisms, but imaging is a correlational method and it is therefore necessary to determine whether this region is essential for such processes. In this paper we present the results of two experiments in which rTMS was applied over the frontal operculum while subjects performed a delayed phonological matching task. We compared the effects of disrupting this area either during the delay (memory) phase or at the response (decision) phase of the task. Delivered at a time when subjects were required to remember the sound of a visually presented word, rTMS impaired the accuracy with which they subsequently performed the task. However, when delivered later in the trial, as the subjects compared the remembered word with a given pseudoword, rTMS did not impair accuracy. Performance by the same subjects on a control task that required the processing of nonverbal visual stimuli was unaffected by the rTMS. Similarly, performance on both tasks was unaffected by rTMS delivered over a more anterior site (pars triangularis). We conclude that the opercular region of the IFG is necessary for the normal operation of phonologically based working memory mechanisms. Furthermore, this study shows that rTMS can shed further light on the precise role of cortical language areas in humans.
|
2022-12-21T17:24:04.155Z
|
171,093,840 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/14651858.CD009903.pub3",
"MAG": "2947787180",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
BACKGROUND
Multiple sclerosis (MS) is a leading cause of neurological disability in young adults. The most widely accepted hypothesis regarding its pathogenesis is that it is an immune-mediated disease. It has been hypothesised that intraluminal defects, compression, or hypoplasia in the internal jugular or azygos veins may be important factors in the pathogenesis of MS. This condition has been named 'chronic cerebrospinal venous insufficiency' (CCSVI). It has been suggested that these intraluminal defects restrict the normal blood flow from the brain and spinal cord, causing the deposition of iron in the brain and the eventual triggering of an auto-immune response. The proposed treatment for CCSVI is venous percutaneous transluminal angioplasty (PTA), which is claimed to improve the blood flow in the brain thereby alleviating some of the symptoms of MS. This is an update of a review first published in 2012.
OBJECTIVES
To assess the benefit and safety of venous PTA in people with MS and CCSVI.
SEARCH METHODS
We searched the Cochrane Multiple Sclerosis and Rare Diseases of the Central Nervous System Group's Specialised Register up to 30 August 2018, CENTRAL (in the Cochrane Library 2018, issue 8), MEDLINE up to 30 August 2018, Embase up to 30 August 2018, metaRegister of Controlled Trials, ClinicalTrials.gov., the Australian New Zealand Clinical Trials Registry, and the World Health Organization (WHO) International Clinical Trials Registry platform. We examined the bibliographies of the included and excluded studies.
SELECTION CRITERIA
We included randomised controlled trials (RCTs) in which PTA and sham interventions were compared in adults with MS and CCSVI.
DATA COLLECTION AND ANALYSIS
Two authors independently assessed study eligibility and risk of bias, and extracted data. We reported results as risk ratios (RR) with 95% confidence intervals (CI). We performed statistical analyses using the random-effects model; and we assessed the certainty of the evidence using GRADE.
MAIN RESULTS
We included three RCTs (238 participants) in this update. One hundred and thirty-four participants were randomised to PTA and 104 to sham treatment. We attributed low risk of bias to two (67%) studies for sequence generation and two (67%) studies for performance bias. All studies were at a low risk of detection bias, attrition bias, reporting bias and other potential sources of bias.There was moderate-quality evidence to suggest that venous PTA did not increase the proportion of patients who had operative or post-operative serious adverse events compared with the sham procedure (RR 3.33, 95% CI 0.36 to 30.44; 3 studies, 238 participants); nor did it increase the proportion of patients who improved on a functional composite measure including walking control, balance, manual dexterity, postvoid residual urine volume, and visual acuity over 12-month follow-up (RR 0.84, 95% CI 0.55 to 1.30; 1 study, 110 participants); nor did it reduce the proportion of patients who experienced new relapses at six- or 12-month follow-up (RR 0.87, 95% CI 0.51 to 1.49; 3 studies, 235 participants). There was no effect of venous PTA on disability worsening measured by the Expanded Disability Status Scale, which was reported at follow-up intervals of six months (one study), 11 months (one study) and 12 months (one study). Quality of life was reported in two studies with no difference between treatment groups. Moderate or severe pain during or post venography was reported in both PTA and sham-procedure participants in all included studies. Venous PTA was not effective in restoring blood flow assessed at one-month (one study) or 12-month follow-up (one study).
AUTHORS' CONCLUSIONS
This systematic review identified moderate-quality evidence that, compared with sham procedure, venous PTA intervention did not provide benefit on patient-centred outcomes (disability, physical or cognitive functions, relapses, quality of life) in people with MS. Venous PTA has proven to be a safe technique but in view of the available evidence of its ineffectiveness, this intervention cannot be recommended in people with MS. All ongoing trials were withdrawn or terminated and hence this updated review is conclusive. No further randomised clinical studies are needed.
|
2022-12-28T15:15:15.445Z
|
79,826,700 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.6084/m9.figshare.5462422.v1",
"MAG": "2761736622",
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},
"license": null,
"status": null,
"url": null
}
|
Did you know that 1 in 5 women experience chronic genital pain with any contact of the vagina? #ItsNotInYourHead is the hashtag associated with a campaign
for a condition called Provoked Vestibulodynia (PVD), initiated by
Dr. Lori Brotto and the Women's Health Research Institute in Vancouver, British Columbia. PVD is characterized by provoking pain with
touch to the vulvar area, and affects up to 10% of women. The campaign aims to
raise awareness about this condition and share evidenced-based research of
psychological treatments that can help manage female genital pain.
|
2022-02-11T03:40:14.121Z
|
246,283,280 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1742-6596/2174/1/012058",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://doi.org/10.1088/1742-6596/2174/1/012058"
}
|
Efficient and low-cost manufacturing methods and adjustable properties are an important way to further promote the application of co-continuous composites. In this paper, a three-dimensional co-continuous composites model with controllable volume fraction is designed. The model uses triply periodic minimal surface (TPMS) as the internal structure and spatial segmentation strategy to accurately control the volume proportion of each phase, which enriches the three-dimensional modeling method of co-continuous composites and provides new ideas and methods for the wide application of co-continuous composites with adjustable characteristics. Finally, samples are manufactured through efficient and low-cost 3D printing technology.
|
2022-03-18T00:36:13.771Z
|
164,437,958 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1353/AEH.2016.0003",
"MAG": "2550025861",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This article reinterprets Dogon migration to colonial Ghana for European clothing as a phenomenon modeled on age group initiation practices on the Dogon Plateau. In initiation rites, young boys who were candidates for the prestigious Association of Masks were subjected to a test, undertaken in caves. Boys who underwent this initiation could only occupy the highest social hierarchy when they mastered the secret language of masks, the sigi so. Labor migration to Ghana in the early and mid twentieth century built upon and altered these social rites; with the rise to prominence of migration, mature men were reborn by migrating to Ghana, where they learned English and brought modern clothing back to their villages. Clothing and other imported items reproduced local institutions of social promotion and reinforced the hierarchical status of their age group. Thus, through migration, young men were initiated into Dogon society through the same processes emphasized by existing initiation rites: uncovering another world, acquiring new knowledge, and adopting new perspectives. For relatives who remained in the village, the human nature of migrants changed, as their modern clothing upon their clean bodies conferred upon them the image of men who had reached new social heights.
|
2022-08-27T12:36:19.618Z
|
154,747,304 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.17233/SE.58967",
"MAG": "2167151510",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Bu calismanin temel amaci, aralarindaki ekonomik butunlesmenin giderek arttigi OECD ulkelerinde satin alma gucu paritesi (SAGP) hipotezinin gecerliligini test etmektir. SAGP hipotezi, reel doviz kurunun kendi ortalamasina donme egiliminde olacagini ifade etmektedir. Bu calismada 25 OECD ulkesi icin SAGP hipotezi 1970-2013 donemine ait yillik veriler kullanilarak analiz edilmektedir. Calismada dogrusal olmayan zaman serisi teknigine dayanan KSS ve AESTAR test prosedurleri kullanilmaktadir. Elde edilen bulgular, AESTAR surecinin KSS surecinden daha guclu kanitlar sundugunu gostermekte ve 25 OECD ulkesinden 20 tanesinde SAGP’nin gecerli oldugunu ortaya koymaktadir.
|
2022-09-01T12:23:11.126Z
|
18,363,894 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/NLPKE.2008.4906751",
"MAG": "2099750989",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Because of many duplicated web pages existing on the web, search engines need to find and remove them, not only for saving process time and hardware resource, but also for ensuring that users can get the result information without many replicas. In this paper, we propose a method to find and remove duplicated Chinese Web pages for search engine. First we describe a scheme based on semantic keywords combined with sentence overlapping, and then show an implemented prototype, with the experimental results that suggest the prototype work well under a proper setting.
|
2022-09-07T13:04:43.895Z
|
153,341,829 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1108/TCJ-01-2014-0005",
"MAG": "1967230327",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Case description
The case highlights a $1.4 billion fraud committed by the founder of a NYSE listed, Information Technology Services firm in India. In response to the crisis, the Indian government appointed an interim board to find a strategic investor in the company. The case traces the events leading to the fall of the company. Students are asked to analyze the governance and intermediation failures, assess the financial position of the company and to estimate the intrinsic value of the company from an acquirer's perspective.
|
2022-09-08T08:28:02.391Z
|
544,972 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICME.2006.262425",
"MAG": "2096144387",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this paper we propose an optimal and robust correlation technique for the local motion estimation purposes. It is based on the maximization of a statistical robust matching function, which is computed in the frequency domain and therefore can be implemented by fast transformation algorithms. We show that our method achieves a significant speed up and robustness over the full search block-matching algorithm. We also present a comparative performance analysis, which shows that the proposed method greatly outperforms the state-of-the-art in correlation motion estimation
|
2022-09-14T15:49:14.718Z
|
35,787,851 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/den.12244",
"MAG": "1556579295",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Currently, the strategy for real‐time endoscopic diagnosis of duodenal, including ampullary, adenoma is still unclear. In the era of high‐definition and magnification endoscopy, using this modality for the detection and diagnosis of these neoplasms is very challenging for endoscopists. Over the past 10 years, many instruments have been developed to improve the detection rate of duodenal and ampullary polyps and to distinguish between adenoma and non‐adenoma. The present review will focus on these novel methods and their usefulness in the diagnosis of ampullary and non‐ampullary adenoma.
|
2022-12-10T04:12:02.261Z
|
15,693,644 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1467-8454.2006.00291.x",
"MAG": "2036867853",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://ageconsearch.umn.edu/record/151167/files/WPR04_8.pdf"
}
|
Analysis of the equity premium puzzle has focused on private sector capital markets. The object of this paper is to consider the welfare and policy implications of each of the broad classes of explanations of the equity premium puzzle. As would be expected, the greater the deviation from the first-best outcome implied by a given explanation of the equity premium puzzle, the more interventionist are the implied policy conclusions. Nevertheless, even explanations of the equity premium puzzle consistent with a general consumption-based asset pricing model have important welfare and policy implications.
|
2022-12-11T07:55:59.898Z
|
138,042,806 |
{
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"ArXiv": null,
"DOI": "10.2497/JJSPM.48.1029",
"MAG": "2319582677",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In the present study, the novel granulation method, spray fluidized bed granulation method was used to produce the granules. Subsequently compacts of the granules were produced through a series of process of dry compaction and sintering under atmospheric pressure. The effects of the properties of granules on compacts and sintered compacts were investigated.First, the granules with target size and good flowability could be produced by using the granulator. The granules were found to have spherical shapes and smooth surfaces. Second, compaction of the granules with sharp size distribution and good flowability showed low fluctuation in flexural strength. Third, granules with low strength were useful for the production of sintered compacts with highly density and flexural strength.In addition to granulation, the granulator has ability to perform the coating of the granules. For pharmaceutical materials, coating of granules and subsequent compaction was performed. The results showed coating operation enhanced the strength of compacts. For ceramic materials, similar achievement is expected.
|
2022-12-13T00:08:23.033Z
|
192,451,557 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1163/15685292-02001005",
"MAG": "2381471620",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Since the so-called Dong Qichang album was discovered by Berthold Laufer in Xi’an, Shaanxi Province, China at the beginning of last century, several papers have been published about it by scholars such as Laufer himself, Josef Jennes, and Noel Golvers. This article, based on former related research, describes the discovery of Laufer, the contents of the album, the style of the paintings in it, and their European prototypes, and discusses the historical meanings of this album. The author concludes that the painter of this album may not be a Chinese convert and argues that although the quality of these paintings is quite low, they may be regarded as historical sources to deepen our understanding of the history of Sino-European artistic exchanges.
|
2022-02-08T08:46:33.516Z
|
96,289,932 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/0959-5309/50/2/307",
"MAG": "2000246850",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Experiments have been made to determine the intensity of a γ ray of 3.2 MV., suspected to be emitted by ThC" - Th.Pb, by comparing the number of recoil protons from deuterium with those due to the well known γ ray of 2.62 MV. It appears most probable that between one and three quanta are emitted in every hundred disintegrations. This result is shown to lend support to the view that it is practicable to assign to the various nuclear states experimental spin values which can be used consistently in different sets of selection rules.
|
2022-07-02T07:05:06.858Z
|
44,546,321 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/1524839903258820",
"MAG": "2125892982",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
There are a number of options available for those who wish to pursue a doctoral degree. In addition to the traditional method of attending classes at a brick and mortar institution, this article describes two of those options. One is a combination of the traditional and nontraditional Internet and on-line approach. The other is a nontraditional route to the doctorate that is completely Internet based. Both options haves merits and suit different people for different reasons. This article describes each of these alternative routes to the doctorate through the words and experiences of two professionals who have followed paths less traveled.
|
2022-07-22T06:32:36.432Z
|
250,795,586 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/1674-1056/24/9/098102",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We propose to achieve a high-efficiency wideband flat focusing reflector using metasurfaces. To obtain the wide band, the polarization conversion mechanism is introduced into the reflector design, based on the fact that the reflection phases of cross-polarized waves are linear in quite a wide band. This facilitates the design of wideband parabolic reflection phase profile. As an example, we design two reflective focusing metasurfaces with one- and two-dimensional in-plane parabolic reflection phase profiles based on elliptical split ring resonators (ESRRs). Both the simulation and experiment verify the wideband focusing performance in 10.0–22.0 GHz of the flat reflectors. Due to the wide operating band, such reflectors have important application values in communication, detection, measurement, imaging, etc.
|
2022-07-31T09:02:39.893Z
|
9,024,277 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4103/0974-2727.180786",
"MAG": "2340276856",
"PubMedCentral": "4866388"
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://doi.org/10.4103/0974-2727.180786"
}
|
Introduction: The high prevalence, severity, and prematurity of coronary artery disease (CAD) in the Indian population cannot be completely explained by the conventional lipid parameters and the existing lipid indices. Aims and Objectives: To calculate newly defined advanced atherogenic index (AAI) in premature CAD patients and compare it between cases and controls and Correlate its values with the existing indices. Material and Methods: One hundred and twenty premature CAD patients and an equal number of age and sex matched healthy individuals were included in this study. Lipid profile and nonconventional lipid parameters like oxidized Low density lipoprotein (OX LDL), small dense LDL (SD LDL), lipoprotein (a) apolipoprotein B (Apo B), and apolipoprotein A1 (Apo A1) were estimated and their values were used to define AAI and existing lipid indices like AI, lipid tetrad index (LTI) and lipid pentad index (LPI). Results: The mean age of cases and controls was 37.29 + 4.50 and 36.13 + 3.53 years, respectively. The value of AAI was highly significant in cases (3461.22 ± 45.20) as compared to controls (305.84 ± 21.80). AAI has shown better statistical significance and correlation (P < 0.0001, r = 0.737) as compared to the earlier indices such as AI (P < 0.01, r = 0.52), LTI (P < 0.001, r = 0.677) and LPI (P < 0.001, r = 0.622) in premature CAD. Kolmogorov D statistic and cumulative distribution function plot has shown that AAI can discriminate cases and controls more accurately as compared to the earlier indices. Conclusion: Statistically AAI appears to be a better marker of consolidated lipid risk in premature CAD patients as compared to the earlier indices.
|
2022-09-03T16:07:07.211Z
|
14,823,450 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/HPSR.2001.923658",
"MAG": "2152077195",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Multicast tree recovery in protocol independent multicast-sparse mode (PIM-SM) networks is initiated by state changes in the underlying unicast routing protocol. A substantial part of the subsequent data loss can be attributed to the non-reductive events, e.g. link addition. We propose and evaluate an improvement to the standard PIM-SM recovery procedure, showing that the data loss can be significantly decreased regardless of the topology and session parameters.
|
2022-09-06T10:06:46.216Z
|
33,291,846 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.20471/acc.2016.55.03.18",
"MAG": "2586247619",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://hrcak.srce.hr/file/254707"
}
|
Spinal metastatic disease is a rather common occurrence and definitely warrants
attention and treatment due to the high likelihood of leaving cancer patients severely disabled in their
final months of life. Recent developments in the understanding of the behavior of different tumor
types, as well as advances in surgical treatment, are allowing for the evolution of treatment algorithms,
especially when surgical treatment is to be considered. This paper gives an overview of the decision-making
process and the array of surgical options currently available.
|
2022-09-15T05:09:03.097Z
|
242,623,304 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21203/rs.3.rs-75397/v1",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GREEN",
"url": "https://doi.org/10.21203/rs.3.rs-75397/v1"
}
|
Background: Chemotherapy-induced peripheral neuropathy (CIPN) is a dose limiting toxicity that poses a major clinical challenge when managing patients receiving specific chemotherapy regimens (e.g. taxanes and Bortezomib). There is a growing body of literature that suggests acupuncture can lead to improvements in CIPN symptoms. Objective: To evaluate the effectiveness of acupuncture as a management tool for CIPN by comparing use of acupuncture with standard care (Acupuncture) against standard care alone (Control), to reduce symptoms of CIPN.Methods: This two-site clinical trial used a phase II, randomised, parallel group design to investigate the effectiveness of a 10-week course of acupuncture. Patients experiencing CIPN of ≥ Grade II (CTCAE v4.03), recording a ‘Most Troublesome’ CIPN symptom score of ≥ 3 using the "Measure Yourself Medical Outcome Profile" (MYMOP 2), were randomised (1:1) to ‘Acupuncture’ or ‘Control’ (note: Patients in Control were offered acupuncture off trial at the end of their study period). Primary endpoint was a ≥ 2-point improvement (success) in MYMOP2 score at week 10. 100 participants (120 randomised to allow for attrition) were required (90% power; 10% one-sided alpha) for a hypothesised improvement in success proportions from 30% to 55% using a primary analysis model with logistic regression adjusted for stratification factors and baseline MYMOP2 scores.Results: Primary MYMOP2 outcome data at week 10 was available for 108 of 120 randomised participants. There were 36/53 (68%) successes in ‘Acupuncture’ compared to 18/55 (33%) in ‘Control’. The adjusted success odds ratio was 4.3 (95% CI 1.9 to 9.6; 2p < 0.001; Acupuncture vs Control). Beneficial effects were also seen in the secondary outcome data, including clinicians’ grading of neuropathy, EORTC QLQ-CIPN20, QLQ-C30 summary scores and patient reported pain scores.Conclusion: A 10-week course of acupuncture resulted in measureable improvement in participants symptoms of CIPN. The results warrant further investigation within a phase III trial. Trial Registration: Trial No. NCT02275403 on Clinicaltrials.gov, registered on 22nd October 2014.
|
2022-12-13T08:06:55.123Z
|
14,967,729 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1371/journal.ppat.1004812",
"MAG": "2026443363",
"PubMedCentral": "4395118"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004812&type=printable"
}
|
The mechanism by which immunity to Herpes Simplex Virus (HSV) is initiated is not completely defined. HSV initially infects mucosal epidermis prior to entering nerve endings. In mice, epidermal Langerhans cells (LCs) are the first dendritic cells (DCs) to encounter HSV, but it is CD103+ dermal DCs that carry viral antigen to lymph nodes for antigen presentation, suggesting DC cross-talk in skin. In this study, we compared topically HSV-1 infected human foreskin explants with biopsies of initial human genital herpes lesions to show LCs are initially infected then emigrate into the dermis. Here, LCs bearing markers of maturation and apoptosis formed large cell clusters with BDCA3+ dermal DCs (thought to be equivalent to murine CD103+ dermal DCs) and DC-SIGN+ DCs/macrophages. HSV-expressing LC fragments were observed inside the dermal DCs/macrophages and the BDCA3+ dermal DCs had up-regulated a damaged cell uptake receptor CLEC9A. No other infected epidermal cells interacted with dermal DCs. Correspondingly, LCs isolated from human skin and infected with HSV-1 in vitro also underwent apoptosis and were taken up by similarly isolated BDCA3+ dermal DCs and DC-SIGN+ cells. Thus, we conclude a viral antigen relay takes place where HSV infected LCs undergo apoptosis and are taken up by dermal DCs for subsequent antigen presentation. This provides a rationale for targeting these cells with mucosal or perhaps intradermal HSV immunization.
|
2022-12-19T06:19:32.362Z
|
20,600,658 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1378/chest.08-2697",
"MAG": "1600451925",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc2821286?pdf=render"
}
|
BACKGROUND
Platelet activation with subsequent neutrophilic adherence to the vasculature initiates ischemia-reperfusion injury. We hypothesized that higher plasma P-selectin levels reflecting platelet activation would therefore be associated with primary graft dysfunction (PGD) after lung transplantation.
METHODS
In a prospective, multicenter cohort study of 376 patients who had undergone lung transplantation between 2002 and 2007, we measured soluble P-selectin levels before lung transplantation and at 6 and 24 h after lung reperfusion in 20 patients with grade III PGD (Pao(2)/fraction of inspired oxygen, < 200 mm Hg [with alveolar infiltrates seen on chest radiographs]) at 72 h after transplantation and 61 control subjects without PGD.
RESULTS
Higher postoperative soluble P-selectin levels were associated with an increased risk of PGD at 72 h after transplantation (odds ratio [OR] per 1 natural log increase in soluble P-selectin at 6 h after lung allograft reperfusion, 3.5; 95% confidence interval [CI], 1.01 to 11.8; p = 0.048) and at 24 h after lung allograft reperfusion (OR, 4.8; 95% CI, 1.4 to 16.1; p = 0.01). Higher preoperative mean pulmonary artery pressure and the use of cardiopulmonary bypass were also associated with an increased risk of PGD.
CONCLUSION
Higher postoperative soluble P-selectin levels were associated with an increased risk of PGD at 72 h following lung transplantation.
|
2022-12-23T22:20:48.663Z
|
10,454,425 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1073/PNAS.95.14.7987",
"MAG": "2075054245",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Hypoxia induces a group of physiologically important genes such as erythropoietin and vascular endothelial growth factor. These genes are transcriptionally up-regulated by hypoxia-inducible factor 1 (HIF-1), a global regulator that belongs to the basic helix-loop-helix PAS family. Although HIF-1 is a heterodimer composed of alpha and beta subunits, its activity is primarily determined by hypoxia-induced stabilization of HIF-1alpha, which is otherwise rapidly degraded in oxygenated cells. We report the identification of an oxygen-dependent degradation (ODD) domain within HIF-1alpha that controls its degradation by the ubiquitin-proteasome pathway. The ODD domain consists of approximately 200 amino acid residues, located in the central region of HIF-1alpha. Because portions of the domain independently confer degradation of HIF-1alpha, deletion of this entire region is required to give rise to a stable HIF-1alpha, capable of heterodimerization, DNA-binding, and transactivation in the absence of hypoxic signaling. Conversely, the ODD domain alone confers oxygen-dependent instability when fused to a stable protein, Gal4. Hence, the ODD domain plays a pivotal role for regulating HIF-1 activity and thereby may provide a means of controlling gene expression by changes in oxygen tension.
|
2023-01-01T17:39:51.532Z
|
108,453,094 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/13588265.2011.648514",
"MAG": "2177865966",
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "http://publications.lib.chalmers.se/records/fulltext/local_156949.pdf"
}
|
Frontal collisions between passenger cars and trucks are the severest vehicle-to-vehicle collisions observed in accident statistics. Regulation 93 was developed to reduce the risk of fatal injury by preventing passenger cars from underriding heavy truck structures. The regulation does not fully address the higher energy of content in these collisions where passenger car structures cannot be expected to have sufficient energy-absorbing capacity. The performance of a front underrun protective device (FUPD) incorporated into a finite element truck model was evaluated and compared with earlier studies by the authors. In particular, structural interaction of the car with the truck structures was investigated. The packing of the FUPD and truck structures was a critical factor for the FUPD performance. It was found that when the vertical offset between the FUPD and truck frame rails is too small, the efficiency of the FUPD is decreased. Incorporating deformable truck frame elements is only beneficial if the offset is at least 220 mm.
|
2022-02-10T07:02:28.116Z
|
249,086,390 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.14210/contrapontos.v22n1.p175-187",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://periodicos.univali.br/index.php/rc/article/download/17778/10679"
}
|
A Internet dos Corpos (IoB) é a rede que se constitui entre os diferentes dispositivos associados de forma direta ao corpo físico. Esse estudo, de natureza qualitativa e exploratória, se apoia na revisão narrativa de literatura para mapear realidades emergentes que exploram a relação corpo-tecnologia em contexto híbrido, a fim de propor um modelo teórico para analisar as arquiteturas digitais de interação que se constituem a partir dessa inter-relação, para balizar a proposição de metodologias e práticas pedagógicas na perspectiva de uma Educação Digital onLife. A partir do tensionamento entre os conceitos, destacamos quatro categorias que podem balizar a análise de arquiteturas digitais de interação considerando o entrelaçamento entre as tecnologias IoB e as realidades digitais emergentes: espaço-rede; actantes; processo sociocomunicacional; movimento das associações.
|
2022-07-31T11:39:21.842Z
|
117,448,340 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21236/ada229675",
"MAG": "1605639124",
"PubMedCentral": null
},
"license": null,
"status": "CLOSED",
"url": null
}
|
Abstract : Two models are presented for the response times of different operators to different tasks where response is initiated by one or more cues provided by the system. One model for the log-response times is a mixed or latent factor model with unequal case fixed effects and variances. The other model for the log-response times is a non-Gaussian log-extreme-value model. Procedures for estimating the parameters by maximum likelihood are presented. The models are used to analyze response time data from simulator experiments involving nuclear power plant operators performing certain safety-related tasks. The findings of the models are critiqued and applications to risk analysis are sketched. (KR)
|
2022-09-06T04:01:27.703Z
|