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255M
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235,280,959 |
{
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"DOI": "10.1088/1757-899X/1107/1/012210",
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|
Passive building strategies in tropical climates are believed to create thermal comfort, thereby enhancing the productivity of the workforce in office buildings. Very little study, however, exists on the impact of these passive design strategies on the productivity of workers in office buildings. This study presents the results of the study on the impact of passive design strategies on the productivity of workers, taking samples from office buildings in Lagos, Nigeria. Copies of questionnaires were administered to gather the required data. Observation guides were also utilised to document passive design features in the buildings studies. Passive design strategies such as; building orientation and the optimisation of solar and ventilation by the use of shading devices were significant strategies in predicting workers’ productivity.
|
2022-12-30T01:03:11.374Z
|
22,446,407 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/HISB.2012.34",
"MAG": "2087796542",
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|
In this post-genomic era it is clear that the sum of the cellular gene expression state determines the cellular phenotypes. The challenge we now face is to keep up the bioinformatics analysis and to understand the genome blueprint. In our lab we applied and developed bioinformatics and systems biology tools for deciphering cancer and stem cell transcriptome data. Cancer stem-like cells were isolated as colonospheres from primary colon cancer tissues and cell lines and characterized their gene expression patterns and genetic networks. Expanded colon cancer spheres had many features of cancer stem cells, including chemoresistance and radioresistance, the ability to initiate tumor formation, and activation of epithelial-mesenchymal transition (EMT). SNAIL, an activator of EMT, was expressed at high levels by CRC colonospheres. smRNA-Seq and genetic network analyses revealed that SNAIL activates genes and microRNAs, such as IL8 and miR-146a, in colonospheres. Blocking IL-8 or miR-146a expression/activity disrupted SNAIL-induced stem cell-like features of colonospheres. Strategies that disrupt the SNAIL-IL8 and SNAIL-miR146a pathways can be developed to block tumor formation by colon cancer stem-like cells. We also applied our systems on brain tumor research. Atypical teratoid/rhabdoid tumor (AT/RT) is a highly malignant pediatric brain tumor often misdiagnosed as other embryonal brain tumors such as medulloblastoma (MB). AT/RT prognosis is much worse than MB, but the underlying mechanisms are unclear. We deciphered the miRNome patterns of AT/RT and MB by sequencing their small RNA fractions. Novel as well as known miRNAs were found deregulated in tumor cells. miR-221 and miR-222 are oncomiRs that can target several tumor suppressors. Further challenge will be to integrate RNA-seq information with systems biology and cloud computing tools.
|
2022-01-27T07:59:43.141Z
|
113,692,256 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.18429/JACOW-IPAC2016-WEPOR053",
"MAG": "2557240042",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This paper discusses model-driven setup of the Continuous Electron Beam Accelerator Facility (CEBAF) for the 12GeV era, focusing on qsUtility. qsUtility is a set of software tools created to perform emittance measurements, analyze those measurements, and compute optics corrections based upon the measurements.qsUtility was developed as a toolset to facilitate reducing machine configuration time and reproducibility by way of an accurate accelerator model, and to provide Operations staff with tools to measure and correct machine optics with little or no assistance from optics experts.
|
2022-01-27T14:11:33.712Z
|
154,480,965 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/J.1747-1346.1994.TB00330.X",
"MAG": "2084800382",
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},
"license": null,
"status": null,
"url": null
}
|
While politicians and political scientists have debated the nature and fate of American political parties for over 200 years, the increasing involvement of the Supreme Court over the past two decades marks a new development in this dialogue. Scholars have disagreed about the implications of judicial involvement, but many have concluded that the Court is becoming increasingly sympathetic to partybuilding efforts. This analysis explores the theoretical orientation toward parties evidenced in the Supreme Court decisions on political patronage. It demonstrates that while these cases were framed as First Amendment disputes, the decisions were predicated on progressive reform values and a nonpartisan model of democracy. This raises a number of questions with regard to the Court's support for stronger parties and the appropriateness of using the judicial forum to determine the role of political parties in American governance.
|
2022-02-09T01:49:31.242Z
|
146,570,947 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/1461957109339695",
"MAG": "2168954072",
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},
"license": null,
"status": null,
"url": null
}
|
Childe withdrew from revolutionary politics after his post-university years in Australia in favour of a career in prehistoric archaeology in Britain. Though remaining a Marxist, his application of Marxist principles to prehistory developed only slowly as his interpretations became more sophisticated. He became increasingly interested in knowledge about prehistory from studying results of the interactions between material remains and their interpretation (in Marxist terms, the relationships between practice and theory). In his paper ‘Retrospect’, Childe (1958b:73) charted the development in his thinking to where he rejected ‘transcendental laws determining history and mechanical causes … automatically shaping its course’ with an understanding that a prehistoric society's knowledge of itself was ‘known or knowable … with its then existing material and conceptual equipment’. Thus the prehistory of Europe could be seen not as a product of Oriental civilization, but as an independent entity. Childe could then write a prehistory of Europe ‘that should be both historical and scientific’ (1958b:74). This book, The Prehistory of European Society (1958a), also demonstrated his use of the epistemology of knowledge to understand prehistory as a sociological phenomenon.
|
2022-09-06T19:13:59.312Z
|
81,001,176 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.15694/MEP.2018.0000204.1",
"MAG": "2891480550",
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},
"license": null,
"status": null,
"url": null
}
|
Background The study of anatomy underpins medical education and is an important facet of clinical practice in various diverse disciplines. We explored the dynamic relationship between arts, anatomy and medicine, along the continuum axis of anatomy, medicine, healthcare and art. Aims Two purposefully open and expressive creative workshops were held within the cadaveric dissection laboratory of the Queen’s University Department of Anatomy; with awide variety of artistic substrates available for faculty and student participants. Themes included: the relationship between art and medicine, the impact art and science have upon each other and the effects of creativity on wellbeing. Accompanying questionnaires included a quantification of perceived relationships between art and medicine; with an estimation of connectedness to feelings. Qualitative items within each questionnaire also addressed key humanistic questions. Comparative analysis of quantitative results was by Student’s t-testing; statistical significance being p values <0.05. There of agree or strongly art and to each other. Qualitative specific, task-oriented to responses aligned with social/gregarious and those related to higher order functioning. Humanistic responses changed across the entire group a largely fixed inclusion of the concept of to broader, those of the resulting representative artwork.
|
2022-09-23T00:46:13.360Z
|
253,176,535 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/16878132221133155",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://doi.org/10.1177/16878132221133155"
}
|
This study developed a dynamic principal component analysis (PCA)-based algorithm for adaptive data detection. The algorithm employs suitable STs on the basis of various data to achieve high accuracy. The scree test (ST) has long been criticized for its subjectivity because no standard applies for retaining the correct number of components or factors when identifying various types of data. This article proposes a novel dynamic ST-based (STB) PCA method wherein a suitable ST is selected in using a support vector machine (SVM) for determining the correct number of components in data detection. The dynamic STB PCA can be employed as a solution to effectively detect various types of data. The proposed detection system can bridge the gap between input data and suitable STs for solving problems encountered when implementing data detection. The experimental results show that the STB PCA provides a ST-selection tool for automatically selecting the most suitable STs, and effectively detected various data using the STs. In the data detection, the proposed method outperforms existing PCA methods that do not consider suitable STs.
|
2022-11-02T20:49:31.613Z
|
117,289,964 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4316/AECE.2017.04001",
"MAG": "2771683339",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The volume and complexity of the data that is generated every day increased in the last years in an exponential manner. For processing the generated data in a quicker way the hardware ...
|
2022-11-28T18:25:05.070Z
|
12,672,919 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1097/TA.0b013e3182115034",
"MAG": "2315985112",
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"license": null,
"status": null,
"url": null
}
|
BACKGROUND
Interleukin (IL)-4 is a pleiotropic cytokine, severed as an important component of the adaptive immune system, and implicated in the pathophysiology of sepsis. Data from other studies show that the -589T/C polymorphism in IL-4 promoter may alter IL-4 expression and susceptibility of inflammatory or autoimmune diseases. Whether this genetic variation is associated with sepsis susceptibility is unknown. The aim of this study was to search for the association of IL-4 -589T/C with the susceptibility to sepsis.
METHODS
The polymorphism was genotyped among 308 severe trauma patients using restriction fragment length polymorphism polymerase chain reaction. The IL-4 and interferon-γ levels in the supernatants were determined with enzyme-linked immunosorbent assay.
RESULTS
The IL-4/-589C allele was shown to be significantly associated with higher plasma IL-4 and lower interferon-γ production after lipopolysaccharide stimulation, indicating its effect on regulating T helper T(H)1/T(H)2 balance. Moreover, homozygosity and heterozygosity for the -589C were associated with an increased susceptibility of sepsis (p = 0.009; OR, 1.69; 95% confidence interval, 1.14-2.51). There was no relationship between the IL-4 -589T/C and multiple organ dysfunction scores in severe trauma patients.
CONCLUSIONS
These results suggest that the IL-4 -589T/C polymorphism might affect T(H)1/T(H)2 balance and predispose trauma patients to susceptibility sepsis.
|
2022-11-29T16:08:03.503Z
|
25,727,761 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1006/RTPH.2002.1559",
"MAG": "28467721",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Animals can be useful predictors of chemical hazards to humans. Growth and development are compressed into a shorter period in animals, which makes interpretation of animal testing inherently more difficult. However, similar events occur in both humans and laboratory animals and testing that covers the full period of animal development can reasonably be considered an appropriate surrogate for human development. Some have proposed an additional 10-fold factor for the extra protection of children when estimating safe exposures. Use of such an additional factor, as required by the Food Quality Protection Act (FQPA), is meant to address the same issues covered by the EPA's database uncertainty factor, UF(D), and additional issues related to exposure uncertainty. Thus, when UF(D) has already been deployed, the EPA modifies its use of the FQPA factor. Based on our analysis, we agree with the EPA. Drawing conclusions about the adequacy of UF(H), the uncertainty factor used to account for intrahuman variability, in terms of its ability to protect children on the basis of the modest data available is challenging. However, virtually all studies available suggest that a high percentage of the population, including children, is protected by using a 10-fold uncertainty factor for human variability or by using a 3.16-fold factor each for toxicokinetic and toxicodynamic variability. Based on specific comparisons for newborns, infants, children, adults, and those with severe disease, the population protected is between 60 and 100%, with the studies in larger populations that include sensitive individuals suggesting that the value is closer to 100%.
|
2022-12-09T23:39:50.389Z
|
31,072,710 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1364/OPEX.12.001908",
"MAG": "2013580923",
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"license": null,
"status": null,
"url": null
}
|
We successfully developed an arbitrary micro-patterning method with femtosecond pulses using a multi-level phase type diffractive optical element (DOE) and a focusing objective lens. The large chromatic dispersion effects of DOE resulting from the spectral bandwidth of femtosecond pulses can be reduced with the appropriate DOE focal length and the proper distance between the DOE and the focusing lens. The method was verified through optical and processing experiments. A partial periodic structure was formed at the designated position. Microstructures were precisely formed on the SiO2 glass surface and inside the glass by irradiating the constructed beam. The points were evenly dispersed with a separation of 5 mum.
|
2022-12-16T07:37:51.230Z
|
206,243,656 |
{
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"ArXiv": null,
"DOI": "10.1017/S0029665113003637",
"MAG": "2163158908",
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"url": null
}
|
This review examines the importance of the placenta in iron metabolism during development and the effect of iron deficiency on maternal and fetal physiology. Iron is an essential micronutrient, required for a wide variety of biological processes. During pregnancy, the mother has to deplete her iron stores in order to provide the baby with adequate amounts. Trans-placental iron transfer involves binding transferrin (Tf)-bound iron to the Tf receptor, uptake into an endosome, acidification, release of iron through divalent metal transporter 1, efflux across the basolateral membrane through ferroportin and oxidation of Fe(II) by zyklopen. An additional haem transport system has been hypothesised, which may explain why certain gene knockouts are not lethal for the developing fetus. Iron deficiency is a common phenomenon during pregnancy, and the placenta adapts by up-regulating its transfer systems, maintaining iron at the expense of the mother. Despite these adaptations, deficiency cannot be completely prevented, and the offspring suffers both short- and long-term consequences. Some of these, at least, may arise from decreased expression of genes involved in the cell cycle and altered expression of transcription factors, such as c-myc, which in turn can produce, for example, kidneys with reduced numbers of nephrons. The mechanism whereby these changes are induced is not certain, but may simply be as a result of the reduced availability of iron resulting in decreased enzyme activity. Since these changes are so significant, and because some of the changes are irreversible, we believe that iron prophylaxis should be considered in all pregnancies.
|
2022-12-20T02:00:29.173Z
|
239,783,299 |
{
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"ACL": null,
"ArXiv": null,
"DOI": "10.1029/2020JG006165",
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|
Millions of lakes worldwide are distributed at latitudes or elevations resulting in the formation of lake ice during winter. Lake ice affects the transfer of energy, heat, light, and material between lakes and their surroundings creating an environment dramatically different from open‐water conditions. While this fundamental restructuring leads to distinct gradients in ions, dissolved gases, and nutrients throughout the water column, surprisingly little is known about the resulting effects on ecosystem processes and food webs, highlighting the lack of a general limnological framework that characterizes the structure and function of lakes under a gradient of ice cover. Drawing from the literature and three novel case studies, we present the Lake Ice Continuum Concept (LICC) as a model for understanding how key aspects of the physical, chemical, and ecological structure and function of lakes vary along a continuum of winter climate conditions mediated by ice and snow cover. We examine key differences in energy, redox, and ecological community structure and describe how they vary in response to shifts in physical mixing dynamics and light availability for lakes with ice and snow cover, lakes with clear ice alone, and lakes lacking winter ice altogether. Global change is driving ice covered lakes toward not only warmer annual average temperatures but also reduced, intermittent or no ice cover. The LICC highlights the wide range of responses of lakes to ongoing climate‐driven changes in ice cover and serves as a reminder of the need to understand the role of winter in the annual aquatic cycle.
|
2022-12-20T17:18:09.550Z
|
5,882,789 |
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"ArXiv": null,
"DOI": "10.1104/PP.38.4.416",
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}
|
Following treatment of Avena coleoptile sections with 0.01 N NaF for 6 hours, an 80% inhibition of growth in the presence of 0.05 M glucose and 2.9 X 10/sup -5/ M indoleacetic acid ensued, followed by partial recovery in fluoride-free solutions. Studies of glucose utilization in the absence of indoleacetic acid showed that absorption of uniformly labeled C/sup 14/ glucose was barley affected but inhibition of incorporation of C/sup 14/ into cellulose and the glucose components of the aqueous and acid-soluble wall fractions was particularly notable. Possible causes of an apparent effect of 0.01 N NaF pretreatment for 6.5 to 7 hours on respiratory pathways, detected by the use of specifically labeled glucose, are discussed. At lower levels of inhibition of growth, the effect on catabolism disappeared but certain effects on the cell wall were still apparent. Interference with metabolism of specific components of the wall including cellulose is considered to be a factor in fluoride inhibition of growth. 20 references, 2 figures.
|
2022-12-23T02:11:35.357Z
|
57,193,239 |
{
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"ArXiv": null,
"DOI": "10.20524/aog.2018.0321",
"MAG": "2899100784",
"PubMedCentral": "6302189"
},
"license": null,
"status": "GOLD",
"url": "https://doi.org/10.20524/aog.2018.0321"
}
|
Tracheoesophageal fistulas (TEF) are pathologic communications between the trachea and esophagus. TEF can lead to significant respiratory distress that may result in lethal respiratory compromise, often due to recurrent and intractable infections. Through the use of endoscopy, some TEF can be successfully repaired using different approaches depending on the size, location, availability, and experience of the treating endoscopist. The aim of this manuscript is to provide an up-to-date review of the endoscopic management of TEF for gastroenterologists.
|
2022-12-29T05:34:47.562Z
|
213,822,731 |
{
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"DOI": "10.18778/1427-9681.12.09",
"MAG": "2982409980",
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},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://czasopisma.uni.lodz.pl/litrossica/article/download/5777/5450"
}
|
В статье рассматривается проблема жанра повести/романа Максима Горького Жизнь Матвея Кожемякина (1911). Автор статьи считает жанр повести синтетическим, ибо в произведении обнаруживаются черты многих жанров, составивших единое художественное целое. В нeм можно отыскать родство с древними летописями/сказаниями, с дневником, а также с несколькими романными разновидностями: с историческим, общественно-бытовым и семейным романами. Вслед за Ежи Ленарчиком, Иво Поспишилом и др. исследователями, автор статьи считает жанровой доминантой произведения семейную хронику, так как во многих горьковских произведениях важное место занимала «семейная мысль», требующая соответствующего ей жанрового оформления.
|
2022-02-08T02:39:19.747Z
|
190,108,294 |
{
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"DOI": "10.4081/HMR.V1I6.686",
"MAG": "1493997024",
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"status": null,
"url": null
}
|
La leucemia linfoblastica acuta (LLA) dell’eta pediatrica e stata caratterizzata negli ultimi quarant’anni da un progressivo miglioramento della sopravvivenza libera da malattia. Questi risultati sono stati ottenuti grazie all’utilizzo di protocolli di polichemioterapia intensiva e di strategie terapeutiche mirate per sottogruppi biologici caratterizzati da malattia a decorso molto favorevole o particolarmente sfavorevole. In questo contesto sono stati elaborati protocolli specifici per il trattamento della LLA negli Infants (eta <1 anno), dei pazienti con LLA Philadelphia positiva e soprattutto per fasce di rischio definite dalle caratteristiche di presentazione della malattia e dalla valutazione della risposta della malattia al trattamento chemioterapico iniziale.
|
2022-02-08T09:33:14.310Z
|
250,817,307 |
{
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"ArXiv": null,
"DOI": "10.1088/0031-9120/40/4/F07",
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}
|
No abstract
|
2022-07-31T07:43:11.205Z
|
250,844,713 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/0953-4075/24/9/013",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The authors have performed quantal calculations of the 3 Sigma - and 3 Pi potential energy curves for interactions of C and He atoms in their ground states. The corresponding cross sections for transitions between the fine structure levels of C have also been determined. Rate coefficients are tabulated for these transitions in the temperature range 10<or=T
|
2022-07-31T13:33:32.196Z
|
111,331,361 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/DAMA.200600281",
"MAG": "2165500072",
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},
"license": null,
"status": null,
"url": null
}
|
Der Beitrag beleuchtet die aktuellen Entwicklungen für den Schallschutz im Mauerwerksbau auf dem Hintergrund der internationalen und nationalen Normung. Es wird erläutert, welche Anforderungen an den Mauerwerksbau durch die europäischen Normen gestellt werden, wie diese umgesetzt werden und wie Handlungsfähigkeit im Rahmen der neuen DIN 4109 erreicht wird. Gezeigt werden soll aber auch, daß es dabei nicht nur um Normungsangelegenheiten geht, sondern daß sich der Mauerwerksbau mit den intensiven Arbeiten der letzten Jahre neue planerische Ansätze und konstruktive Lösungen für den Schallschutz aneignen konnte, die nun für die praktische Anwendung zur Verfügung stehen.
|
2022-09-01T04:01:47.405Z
|
138,975,978 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.12988/CES.2015.53109",
"MAG": "2521220431",
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},
"license": null,
"status": null,
"url": null
}
|
High amount of waste heat emerging from thermal processes performed in the industry can be recovered by means of equipment such as heat pipes, heat exchangers and heat recovery boilers. In this study, thermal performance of a heat recovery device, which enables air-to-air heat transfer, was examined. For this purpose, cross-flow plate-fin heat exchangers were produced by using three different materials, which are aluminum, polymer and cellulose. With the established apparatus, outlet temperatures with different values were obtained for fresh air and exhaust air. Thermal calculations, were performed with the mathematical model developed by using the EffectivenessNumber of Transfer Unit (e NTU) method and their results were compared. It was seen that at the same air rate with the same exhaust air inlet temperature and the same fresh air inlet temperature; when the polymer heat exchanger is used, effectiveness value is 12,6% higher on an average than the aluminum heat exchanger. Similarly, when the cellulose heat exchanger is used, effectiveness value is 14,5% higher on an average than the polymer heat exchanger.
|
2022-06-07T16:43:38.059Z
|
233,135,895 |
{
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"ArXiv": null,
"DOI": "10.1109/ICMMT49418.2020.9386865",
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},
"license": null,
"status": null,
"url": null
}
|
Compact substrate-integrated waveguide (SIW) bandpass filter (BPF) is proposed using a single perturbed triple-mode cavity. The first three resonances of the cavity can be flexibly controlled by the centered cross-shaped perturbations so that the third-order response can be realized by shifting the first three resonant frequencies close to each other. Three transmission zeros (TZs) can also be introduced due to the arrangement of two feeding ports and the interference between different modes. A third-order BPF centered at 12.7 GHz is synthesized, designed, fabricated, and tested with good agreements between the measured and simulated results.
|
2022-09-05T22:32:07.458Z
|
41,441,584 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.3892/OR.12.2.259",
"MAG": "2008224094",
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|
Receptor-binding cancer antigen expressed on SiSo cells (RCAS1) is a recently discovered human tumor-associated antigen expressed in a wide variety of cancer tissues. It has been suggested that tumor cells evade from immune surveillance by expression of RCAS1. We investigated whether RCAS1 is expressed in human oral squamous cell carcinomas (HOSCCs) or HOSCC (HSC-2, -3, -4, Ca9-22 and KB) cells and whether tumor cells expressing RCAS1, induce apoptosis in its receptor-positive cells, peripheral blood lymphocytes (PBLs). RCAS1 transcripts and proteins were detected in five HOSCC cell types. Immunohistochemical examinations revealed that RCAS1 was slightly to moderately positive in 32 of 40 cases (80%) of HOSCCs. Furthermore, the frequency of RCAS1 expression in HOSCC increased with advancing tumor stage according to the pTNM system. Confocal laser microscopy and DNA fragmentation assay showed that PBLs, which were stimulated with IL-2, underwent apoptosis by co-culturing with KB cells. It was also confirmed by Western dot blotting that soluble RCAS1 is secreted into culture supernatants of KB cells. The apoptotic tumor-infiltrating lymphocytes (TILs) were detected around RCAS1-positive tumor cells in HOSCCs by TUNEL method. These results suggest that RCAS1 expression might be associated with progression of oral tumors and offer a possible mechanism for oral cancer immune escape.
|
2022-12-09T02:16:38.029Z
|
253,298,392 |
{
"externalids": {
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"ArXiv": null,
"DOI": "10.1210/jendso/bvac150.487",
"MAG": null,
"PubMedCentral": "9625074"
},
"license": null,
"status": "GREEN",
"url": "https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9625074"
}
|
Abstract Introduction Statin associated necrotizing autoimmune myopathy is an extremely rare side effects of stain use. The incidence is approximately 2-3/100,000 Patients treated with statins. It usually associated with significant proximal muscle weakness, strikingly elevated creatine kinase (CK) levels and persistent symptoms despitestatin discontinuation. Here, we present a case with necrotizing myopathy after statin use as a reminder to clinicians for appropriately suspicious of this phenomenon while on treatment of statins. Clinical case: A 35 year old male with a past medical history of Autism, Type 2 Diabetes Mellitus, Hyperlipidemia, and Hypertension was brought to emergency room for right leg pain. Family states he had difficulty walking for a few weeks and had a fall from couch a week ago. Initial Vitals showed HR at 134 bpm, temp 35.9, BP 157/85 mmHg, RR 19 breaths/min. Labs showed Creatinine. 3.29 mg/dL, CO2 24 mmol/L, Na 141 mmol/L, K 4.2 mmol/L, Ca 9.5 mg/dL, glucose 265 mg/dL, AST/ALT 914/919 units/L, CK>14,000 units/L, WBC 9.2 thou/mcL, Hb 12.6 g/dL, TSH 9.42 mcIU/mL, Free T3 1.41 pg/mL, Free T4 0.95 mcg/dL. Urinalysis showed large blood with RBC of 1. Myoglobin>8750 mcg/L. Neuro motor exam showed strength 4/5 in bilateral lower extremities. His home medications including atorvastatin 20 mg nightly for 2 years, metformin and olmesartan, which all had been held. He was treated for rhabdomyolysis with aggressive hydration and Creatinine was improving. However, CK continued trending up to 42,915 units/L on day 5 with unreleased symptoms of lower extremity weakness. Neurology was consulted. Differential diagnosis of myopathy were suspected. His CK was continue to trend up to 45,585 units/L on day 10. Decision was made to have muscle biopsy with pathology showed: necrotizing myopathy without any clear evidence of inflammation. Although some autoimmune necrotizing myopathy may not show inflammation like those seen with HMG-CR antibodies or signal recognition antigen antibodies. Autoantibodies against 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (HMGCR Ab) was above 550. Following the biopsy, he received IV Solu-medrol 1g daily×4 doses, and then PO Prednisone 80 mg daily and then tapered down to 40 mg daily. He was also promptly started on IVIG 400 mg/kg/day for 5 days and methotrexate 7.5 mg weekly. His CK started to improve, down to 5815 units/L three weeks later. No significant improvement of strength. Conclusion Our case demonstrates that the appropriate diagnosis of statin induced necrotizing autoimmune myopathy with muscle biopsy and HMGCR Ab. We also wanted to alert future clinicians to have an early suspicious of such rare side effect and initiate treatment as early as possible which may bring the maximum benefit for patients. Presentation: No date and time listed
|
2022-12-10T09:37:42.279Z
|
233,145,252 |
{
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"ArXiv": null,
"DOI": "10.36380/JWPR.2021.10",
"MAG": "3141616170",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The production and reproduction performance of chicken depends on their hormonal status, especially progesterone hormone, which has been known to correlate with egg production. The present study aimed to analyze the effect of progesterone hormone injection on Arabic Gold chickens (Gallus turcicus) regarding egg production and luteinizing hormone concentration in blood plasma. A total number of 60 Arabic Gold chickens aged 26-weeks were divided into three groups based on injected hormone concentration (P0: control; P1: 1 mg/chicken; P2: 2 mg/chicken). The study was conducted using a completely randomized design and the obtained data were analyzed with a descriptive analysis for qualitative data and one-way analysis of variance followed with Duncan’s Multiple Range Test as a post hoc test for the quantitative data. The results presented that progesterone hormone injection had a significant effect on hen day production two and six weeks after injection. The P1 group was able to reach its peak production (82.9%) at week 29, while the P2 group reached its peak at week 26 (78.9%). In addition, it was found that the P2 group produced a soft-shelled egg and double egg yolk. Progesterone injection led to no significant effect on the egg weight, shape index, fertility, embryo viability, hatchability, and chick weight at hatch. The luteinizing hormone concentration was higher in P2 (1.52 ng/ml), compared to P0 (1.36 ng/ml) and P1 (1.34 ng/ml) groups. It was concluded that progesterone hormone injection during the production phase of Arabic Gold chicken had a significant effect on egg production and caused varying egg production peak and luteinizing hormone concentration.
|
2022-12-11T23:59:31.341Z
|
244,618,308 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.11646/PHYTOTAXA.523.3.5",
"MAG": "3206148340",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Rohdea wangiana is described as a new species from SW Sichuan, China. It is somewhat similar to R. pachynema in based on spikes without a marked terminal tuft of sterile bracts and deltoid filaments, but differs based on a combination of the following characters: leaf blades marginally serrulate; peduncle ebracteate; one bract per flower; perianth externally angulate, perianth segments distally denticulate or three-lobed, small lobe present between adjacent filaments, filaments inserted to base of perianth segments; stigma obviously lower than stamens; lack of slender stolons.
|
2022-12-12T17:55:56.601Z
|
162,117,549 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S1047759400020006",
"MAG": "1685277146",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
L'obélisque d'Arles est mentionné pour la première fois en 1389, au sud de la ville, au-delà des murs, sur l'emplacement du cirque romain dont il ornait la spina. Il fut redécouvert en 1565 et était alors scindé en deux grands fragments de 4,60 m pour la partie supérieure et de 10,80 m pour la base, et une pointe, signalée au XVIe s. dans le couvent des religieuses de Saint-Césaire, qui n'a malheureusement jamais été retrouvée. Depuis son érection entre les 20 et 26 mars 1676 devant l'Hôtel de Ville pour la plus grande gloire de Louis XIV (fig. 1), il fut l'objet d'un vif débat quant à l'origine de la roche le composant. L'attribution à une carrière varoise et plus particulièrement de l'Esterel qui fut longtemps retenue, est désormais à écarter. On dispose actuellement d'indications quant à une possible provenance orientale, bien que non égyptienne. Cette nouvelle identification permet de reprendre le dossier de l'obélisque et de proposer une date pour son installation. Pour L. Lazzarini, la pierre serait une quartzo-monzonite provenant d'une carrière située près d'Alexandrie de Troade (Turquie) qui n'a commencé à exporter qu'à partir du IIe s. et qui connut son apogée durant l'Antiquité tardive. On peut donc supposer que la mise en place de cet obélisque au milieu du cirque remonte vraisemblablement à cette dernière période et l'obélisque arlésien serait alors l'un des rares monolithes d'origine orientale, sinon le seul, installé pendant l'Antiquité en Occident en dehors de tous ceux destinés à décorer Rome.
|
2022-12-14T20:29:03.650Z
|
3,747,819 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1364/OL.43.001103",
"MAG": "2794368601",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This Letter reports on the effect of self-absorption on measured temperature for color-ratio soot pyrometry with a color camera. A series of increasingly nitrogen diluted atmospheric pressure ethylene/air laminar coflow diffusion flames are studied, providing flames with different optical path lengths, soot loading, and soot optical properties. Numerical calculations are used to simulate the change in collected flame emission signal with and without light attenuation using experimentally measured maps of the soot absorption coefficient. This parameter implicitly contains information about soot volume fraction and soot optical properties. The ratio of these calculations is used to correct the raw color-channel signals, resulting in temperature maps with improved accuracy. The change in calculated temperature varies spatially within each flame, with the maximum correction quantified to be 22 K for a flame with a maximum optical depth of 0.31. This correction is as much as 42 and 75 K for simulated flames with the same optical properties, structure, and a factor of two and five increase in soot volume fraction, respectively.
|
2022-12-13T19:09:15.210Z
|
1,387,938 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/BIT.260180608",
"MAG": "2082067144",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The pressure required for initiation of flow when freeze‐pressing with the X‐press is related to the phase boundaries of water, particularly those between ice I and liquid even at temperatures around −25°C and lower. Widening the orifice of the pressure chamber to diameters larger than 2.5 mm leads to lower pressures and less extensive cell disintegration.
|
2022-12-18T08:39:02.993Z
|
203,457,774 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21203/rs.2.10104/v1",
"MAG": "2972986313",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GREEN",
"url": "https://doi.org/10.1186/s12879-019-4705-9"
}
|
Objectives: To depict the Spatiotemporal epidemiological characteristics of the incidence of scarlet fever in Shenyang, China, in 2018 so as to provide the scientific basis for effective strategies of scarlet control and prevention. Methods: Excel 2010 was used to demonstrate the temporal distribution at the month level and ArcGIS10.3 was used to demonstrate the spatial distribution at the district/county level. Moran’s autocorrelation coefficient was used to examine the spatial autocorrelation and the Getis-Ord statistic was used to determine the hot-spot areas of scarlet fever. Results: A total of 2,314 scarlet fever cases were reported in Shenyang in 2018 with an annual incidence of 31.24 per 100,000. The incidence among males was higher than that among females(X2=95.013, P≤0.001). A vast majority of the cases (96.89%) were among children aged 3 to 11 years. The highest incidence was 625.34/100,000 in children aged 5-9 years. There are two seasonal peaks occurred in June (Summer-peak) and in December (Winter-peak) in 2018. The incidence of scarlet fever in urban areas was significantly higher than that in rural areas(X2=514.115, P≤0.001).The incidence of scarlet fever was randomly distributed in Shenyang. There are hot-spots areas located in seven districts. Conclusions: Urban areas are the hot spots of scarlet fever and joint prevention and control measures between districts should be applied. Children in the kindergartens and the primary school students are the main population of scarlet fever and the time distribution of scarlet fever is highly consistent with their school and vacation time. It is suggested that measure for prevention and control of scarlet fever in kindergartens and primary schools is the key to control the epidemic of scarlet fever.
|
2022-12-20T12:48:19.936Z
|
11,926,957 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/es401772m",
"MAG": "2318334315",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Equilibrium partition coefficients of organic chemicals from water to an organism or its tissues are typically estimated by using the total lipid content in combination with the octanol-water partition coefficient (K(ow)). This estimation method can cause systematic errors if (1) different lipid types have different sorptive capacities, (2) nonlipid components such as proteins have a significant contribution, and/or (3) K(ow) is not a suitable descriptor. As an alternative, this study proposes a more general model that uses detailed organism and tissue compositions (i.e., contents of storage lipid, membrane lipid, albumin, other proteins, and water) and polyparameter linear free energy relationships (PP-LFERs). The values calculated by the established PP-LFER-composition-based model agree well with experimental in vitro partition coefficients and in vivo steady-state concentration ratios from the literature with a root mean squared error of 0.32-0.53 log units, without any additional fitting. This model estimates a high contribution of the protein fraction to the overall tissue sorptive capacity in lean tissues (e.g., muscle), in particular for H-bond donor polar compounds. Direct model comparison revealed that the simple lipid-octanol model still calculates many tissue-water partition coefficients within 1 log unit of those calculated by the PP-LFER-composition-based model. Thus, the lipid-octanol model can be used as an order-of-magnitude approximation, for example, for multimedia fate modeling, but may not be suitable for more accurate predictions. Storage lipid-rich phases (e.g., adipose, milk) are prone to particularly large systematic errors. The new model provides useful implications for validity of lipid-normalization of concentrations in organisms, interpretation of biomonitoring results, and assessment of toxicity.
|
2022-12-23T19:10:17.755Z
|
15,943,114 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CVPR.2001.990925",
"MAG": "2105795585",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Dynamic textures are sequences of images that exhibit some form of temporal stationarity, such as waves, steam, and foliage. We pose the problem of recognizing and classifying dynamic textures in the space of dynamical systems where each dynamic texture is uniquely represented. Since the space is non-linear, a distance between models must be defined We examine three different distances in the space of autoregressive models and assess their power.
|
2022-12-29T13:44:38.259Z
|
23,249,575 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1073/PNAS.70.7.2020",
"MAG": "2068621998",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Conditions are described under which the catalytic Brdicka currents observed in ammoniacal buffer solutions containing cobalt(III) hexammine chloride or cobalt(II) and very little bovine-serum albumin (0.1-0.2 muM) are purely kinetically controlled. Under these conditions the kinetic current at pH 9.3-10.3 exhibits a sharp maximum followed by a decrease of the current to a well-defined minimum. The maximum and minimum are eliminated in the presence of 5 mM or more concentrated calcium chloride when a short plateau occurs at the potential of the maximum followed by a well-defined second wave. Both currents are kinetically controlled. When the albumin concentration is 2 muM or greater, the kinetic currents approach diffusion control, the rate of diffusion of cobalt(III) or (II) being close to rate determining. Under these conditions the currents become proportional to the cobalt(III) or (II) concentration in the concentration range between 25 and 200 muM.
|
2022-12-30T00:41:39.832Z
|
90,017,146 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3897/JOR.26.19995",
"MAG": "2771432075",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The subfamily Catantopinae is a poorly defined subfamily of the Acrididae, having many genera that require taxonomic clarification. The genus Gemeneta from this subfamily is found in African forests and has only two described species, Gemenetaterrea and Gemenetaopilionoides. However, the original descriptions of the genus relied heavily on external female morphology, and a description of male G.opilionoides was completely lacking. The present work provides the first description of the male of G.opilionoides, a morphological description of both species, including internal genitalia, and clarifies the generic diagnosis. This study is a contribution to a better understanding of the taxonomy of Catantopinae in the tropical forests of Africa.
|
2022-06-18T09:51:27.136Z
|
231,731,439 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/cld.963",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://europepmc.org/articles/pmc7849291?pdf=render"
}
|
Watch a video presentation of this article Watch an interview with the author.
|
2022-07-11T01:37:51.656Z
|
250,826,372 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/0953-8984/2/3/017",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The C*2v(d6)strong-field matrices for S=2 are given in an Oh point-group representation and an EPR theory for d6-C2v systems is established. By means of the eigenvalues and eigenvectors of these matrices, the EPR spectrum of Fe2+ in ZnS:Fe2+ is analysed, the fine structure of the absorption spectrum with Delta S=0 is explained, the paramagnetic g-factors, the zero-field splitting parameters and the Zeeman energy corrections are obtained. The experimental requirements for realising those EPR transitions are discussed and the influences of the excited states on the ground-state spin-Hamiltonian parameters are analysed. Information which can be obtained from the eigenvectors is discussed.
|
2022-07-31T09:09:36.521Z
|
240,978,014 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.35940/ijitee.i8519.078919",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GOLD",
"url": "https://doi.org/10.35940/ijitee.i8519.078919"
}
|
With the presence of computer and internet, a developing variety of hoodlums are utilizing the web to spread a wide extend of illicit materials and wrong information universally in mysterious manner, making criminal personality following troublesome in the cybercrime examination handle. The virtual world provides criminals with an anonymous environment to conduct malicious activities such as malware, sending random messages, spamming, stealing intellectual property and sending ransom e-mails. All of these activities are text in somehow. Therefore, there is a need for a tool in order to identify the author or creator of this criminality by analyzing the text. Text-based Authorship Attribution techniques are used to identify the most possible author from a bunch of potential suspects of text. In this paper, the novel approach is presented for authorship attribution in English text using ASCII based processing approach Using this ASCII based method for authorship attribution help us to obtain better result in terms of accuracy and computational efficiency. The result is based on the text which is posted on social media considering real world data set.
|
2022-10-28T00:47:42.154Z
|
6,203,040 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.21307/IJSSIS-2017-797",
"MAG": "2485706849",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract Iris recognition and favor because of its high recognition rate, noninvasive and simple algorithm and other advantages, in a variety of biometric identification technology is very prominent. The iris texture feature extraction is the core of the iris recognition algorithm. Fractal geometry theory provides new ideas and methods to express nonlinear image information, the fractal dimension is an important parameter of fractal geometry, is a measure of complexity of irregular change, covering blanket dimension can better reflect the graphics changes in different resolution characteristics; missing is the fractal dimension and independent statistics, is a supplement to the fractal dimension, overcome the different texture characteristics may have the same fractal dimension of the problem. This paper presents a blanket and missing items based on the combination of texture feature extraction algorithm, can make full use of radiation in different resolution iris texture information and texture, classification ability make feature matrix has a better. Iris matching is the key of iris recognition. How to effectively carry out the matching of the iris code matrix is the decisive step in iris recognition. In this paper based on the normalized correlation classifier, the matching method of cyclic shift, eliminated from the same eyes of different iris image due to differences in rotation caused, improve matching accuracy.
|
2022-11-04T00:15:14.345Z
|
250,218,572 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1136/bmjopen-2021-057662",
"MAG": null,
"PubMedCentral": "9252208"
},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://bmjopen.bmj.com/content/bmjopen/12/7/e057662.full.pdf"
}
|
Objectives The Menstrual Practice Needs Scale (MPNS) is a comprehensive measure of menstrual self-care experience including access to sufficient, comfortable materials to catch or absorb bleeding, supportive spaces for managing menstruation and for disposal and laundering of used materials. It addresses a critical measurement gap to improve quantitative menstrual health research and programme evaluation. The scale was validated in a population of adolescent schoolgirls. This study appraises its performance among adult women. Design Cross-sectional survey. Setting and participants Seven cognitive interviews provided insights into the interpretability of scale items. A survey of 525 working women who had menstruated in the past 6 months (435 working in markets, 45 in schools and 45 working in healthcare facilities) in Mukono District, Uganda was used to test the dimensionality, reliability and validity of the measure. Results The 36 scale items were well understood by the study population. Dimensionality was tested for the 28 items relevant to women disposing of menstrual materials and 32 items relevant to those washing and reusing materials. The original subscale structure fit with the data, however, fell short of recommended thresholds for those disposing of materials (root mean squared error of approximation, RMSEA=0.069; Comparative Fit Index, CFI=0.840; Trucker-Lewis Index, TLI=0.824). An alternative subscale structure was an acceptable fit for those disposing (RMSEA=0.051; CFI=0.911; TLI=0.897) and reusing materials (RMSEA=0.053; CFI=0.915; TLI=0.904). MPNS total and subscale scores demonstrated acceptable internal consistency. Higher scores reflected more positive menstrual experiences and were associated with well-being (total score r=0.24, p<0.001), not missing work due to the last menstrual period (total score OR=2.47 95% CI 1.42 to 4.30) and confidence to manage menstruation. Conclusions The MPNS offers a valid and reliable way to assess menstrual health needs. The revised factor structure can be used for samples of adult workers. Findings also highlight challenges in assessing the variety of experiences relevant to managing menstrual bleeding.
|
2022-12-14T00:58:57.548Z
|
191,673,593 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.12816/0041134",
"MAG": "2768168755",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://doi.org/10.12816/0041134"
}
|
This article treats the structure of Algerian free poetry’s image, exposing it sartistic dimensions like metaphorical dimension, and its total character and the property of fragmentation which this poem resorts to it sometimes. Also, this article reviews the forms of poetic image, such as the simple one and the complex, the visible one and the invisible, and Its function in the structure of the text which varies between artistic effectiveness and inefficiency, due to the diversity of poetic experiences at a single poem, and the variation between a poem and another.
|
2022-02-08T09:01:20.917Z
|
1,478,350 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/10803548.2001.11076484",
"MAG": "1527286364",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://www.tandfonline.com/doi/pdf/10.1080/10803548.2001.11076484?needAccess=true"
}
|
Team working is the basic way of working in the control rooms of hazardous technologies and therefore its quality is a safety-relevant issue. In addition to the technological competence it is also crucial for the crews to have the necessary communicational skills. During simulator training these skills can only be improved if the simulator use is embedded in an appropriate setting. To support this skill acquisition a computer-supported methodology called COSMOS (COmputer Supported Method for Operators’ Self-assessment) has been developed. With its help more effective communication and more complete shared mental models can be fostered. This paper is a report on the psychological fundamentals and the mathematical model of the COSMOS methodology.
|
2022-02-13T14:36:22.284Z
|
55,540,062 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4172/2472-1042.1000109",
"MAG": "2572120668",
"PubMedCentral": null
},
"license": "CCBY",
"status": "HYBRID",
"url": "https://doi.org/10.4172/2472-1042.1000109"
}
|
Objective: To investigate the resource use and costs associated with the management of metastatic anaplastic lymphoma kinase inhibitors (ALK+) NSCLC in Greece. Methods: The resource use was based on the outcomes of a Delphi panel with seven oncologists and unit costs derived from officially published sources. Results: The average per patient cost in the current treatment pathway (chemotherapy, crizotinib, chemotherapy, palliative care) was estimated at €67,391. The average per patient cost in future scenario 1 (crizotinib, ceritinib, chemotherapy, palliative care) was estimated at €104,571 (treatment duration 26 months) while in future scenario 2 (chemotherapy, ceritinib, chemotherapy, palliative care) was estimated at €134,215 (treatment duration 29.3 months). Conclusion: Ceritinib as second line treatment leads to an increase in total costs reflecting the longer survival
|
2022-02-11T19:48:13.567Z
|
21,571,326 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ESSCIRC.2007.4430356",
"MAG": "2103097680",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A CDR circuit dedicated to satellite embedded data link is presented. This circuit combines an injection locked oscillator, with a phase alignment circuit, to achieve the clock recovery. The circuit was designed in a 130 nm CMOS process from STMicroelectronics. The working range is from 9.6 Gbit/s up to 10.2 Gbit/s, the power dissipation is 94 mW under 1.2 V power supply. The measured eye opening is 60 ps and 240 mV with a BER lower than 1012.
|
2022-09-11T10:09:03.176Z
|
250,318,928 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5812/jjm-122718",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBYNC",
"status": "GOLD",
"url": "https://brieflands.com/articles/jjm-122718.pdf"
}
|
Background: Urinary tract infections represent a major expensive, common public health problem worldwide due to their high prevalence and the difficulties associated with their management. Objectives: This study aimed to characterize the Enterobacter cloacae strains isolated from urinary tract infections in the medical diagnostic laboratories of Shahrekord, Iran. Methods: Urine samples from patients with urinary tract infections from the Shahrekord medical diagnostic laboratories located in Chaharmahal and Bakhtiari Province, Iran, were collected from June 2019 to February 2020. When the samples were cultured, the different isolates of E. cloacae were identified by biochemical tests. Biofilm production capacity was evaluated. Bacterial susceptibility to antibiotics was determined using the Kirby Bauer method, and antibiotic resistance genes were researched by the multiplex PCR technique. Results: In this study, 65 isolates of E. cloacae were obtained. The highest percentage of resistance was observed for co-trimoxazole (84.62%), ampicillin (76.93%), tetracycline (73.85%), and above half of the E. cloacae strain isolates (53,85%) were strongly involved in biofilm production. Some genes, including qnr A, qnr B, qnr S, tetA, tet B, sul1, bla CTXM, bla SHV, and(2)la, ant(3)la, and aac(3)IIa, were detected in the genome of these isolates. Conclusions: The strains are multi-resistant, and their resistance has already reached the carbapenem class. This requires further investigation, and urgent measures must be adopted.
|
2022-10-11T20:49:46.158Z
|
56,089,646 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.17220/ijpes.2018.02.6",
"MAG": "2802803218",
"PubMedCentral": null
},
"license": "CCBYNCND",
"status": "GOLD",
"url": "https://doi.org/10.17220/ijpes.2018.02.6"
}
|
This research has been designed to compare mothers upbringing methods based on adolescents intelligence groups; high-intelligence, low-intelligence and normal. To this purpose, 194 individuals were chosen from among male and female students of ages 14 and 15 from the city of Ghaenat from southern Khorasan province within the educational year of 2015, by the simple-random method in high-intelligence schools, by the census method in low-intelligence schools and by the multi-stage cluster sampling method in normal schools. The tools employed include the Bamrind questionnaire on upbringing methods. Pierson’s codependence coefficient and multi-variant variance analysis have been used for data analysis.
Results indicated that the difference is significant between intelligence groups regarding tyrannical and logical potency and no significant difference in upbringing methods based on freedom. There is positive and significant difference between mothers of children belonging to high and low-intelligence groups regarding authoritarian and logical potency, and mothers of children belonging to the normal and low-intelligence groups. There’s no significant difference between other intelligence groups and upbringing methods.
|
2022-11-18T00:02:45.962Z
|
20,433,444 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1158/1535-7163.MCT-11-0614",
"MAG": "2148622762",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Increased abundance of βII- and βIII-tubulin isotypes in cancer cells confers resistance to vinca and taxoid site drugs; however, the role of these isotypes in the acquired resistance of cancer cells to non-vinca or non-taxoid site binding agents has not been described. Peloruside A (PLA) and laulimalide are the only known non-taxoid site microtubule-stabilizing agents. A human ovarian cancer cell line, 1A9-L4 (L4), previously selected in high concentrations of laulimalide, has both a single point mutation in βI-tubulin and overexpression of βII- and βIII-tubulin. The cells are highly resistant to PLA as well as laulimalide but show no cross-resistance to taxoid site drugs or drugs that bind to the vinca site on β-tubulin. To understand the functional significance of the βII- and βIII-tubulin changes in this resistant cell line, isotype-specific short interfering RNA was used to knock down the expression of the βII and βIII isotypes, and the cellular effects of PLA and laulimalide were examined before and after silencing. It was found that inhibition of βII- and βIII-tubulin partially sensitized L4 cells to PLA and laulimalide, as seen by increased potency of PLA and laulimalide for inducing growth inhibition, cellular tubulin polymerization, microtubule aberrations, and G2-M arrest in the resistant cells. The sensitivity to paclitaxel, vinblastine, ixabepilone, and cisplatin was unaffected by the inhibition of isotype expression. It was concluded that the increased βII- and βIII-tubulin contributed significantly to the resistance phenotype, along with the tubulin structural mutation, and that the altered isotype effect was binding site specific. Mol Cancer Ther; 11(2); 393–404. ©2011 AACR.
|
2022-12-18T10:49:21.756Z
|
73,285,684 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1136/jnnp.41.9.861",
"MAG": "2126918041",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://jnnp.bmj.com/content/jnnp/41/9/861.1.full.pdf"
}
|
A Clinician's View of Neuromuscular Diseases By Michael H. Brooke. (Pp. 225; illustrated; $18.95.) Williams and Wilkins: Baltimore. 1977. In this well-written and readable book Dr Brooke has achieved a comprehensive clinical review of the whole spectrum of neuromuscular disorders. The tone and pace of the book are well set by the epithet to the first chapter on symptoms and signs"Please listen to the patient, he's trying to tell you what disease he has," and by the opening sentence-"It often seems that the urgency with which physicians rush their patients off for laboratory studies has its historical equal only in the migration of lemmings. ... Individual chapters are devoted to systematic descriptions of disorders of the motor neurone, peripheral neuropathies, diseases of the neuromuscular junction, muscular dystrophies, myotonia, inflammatory myopathies, metabolic muscle diseases, abnormal muscle activity, and ending with "congenital (more or less)" muscle diseases. The descriptions are concise but comprehensive and interspersed with clinical photographs and an occasional biopsy photomicrograph. The bibliography is intentionally selective and often recent rather than historical or original. This is a highly individual work which should find appeal with a wide audience of clinicians at all levels.
|
2022-12-18T21:46:26.192Z
|
23,351,282 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1037/1099-9809.12.2.199",
"MAG": "2071754134",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Using a collective case study ethnographic approach, nine individuals comprising three Mexican American families were interviewed about their family bereavement experiences after the death of a child. All families were Catholic, had surviving siblings, and had had three or more years to grieve their loss when interviewed. The deceased children ranged in age from 3 to 14, and all experienced sudden, traumatic, nonsuicide deaths. To provide a broader, contextual picture of their grief experiences, four individuals who supported these family members after the loss were also interviewed. Unique grief experiences were identified, and eight common themes emerged, reflecting the ways in which family members maintained their bond to the deceased: dreams, storytelling, keepsakes, sense of presence, faith-based connections, proximity connections, ongoing rituals, and pictorial remembrances. The cultural implications of family bereavement are highlighted.
|
2022-12-18T22:08:13.376Z
|
14,892,362 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/DIPDMWC.2016.7529384",
"MAG": "2488710014",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In cloud computing, the paradigm of data outsourcing introduces security challenges, which requires an independent auditing service to check the data integrity in the cloud. Many existing integrity checking protocols cannot be applied to the auditing service because they can only deal with static data, but it is natural for the client to dynamically update their remotely stored data. Thus, an efficient and secure auditing protocol enabling data dynamics is desired to convince the client that the data are correctly stored in the cloud. In this work, we propose a privacy-preserving public auditing cloud storage protocol enabling data dynamics in the standard model. Inspired by a recent homomorphic network coding signature scheme, we employ a data integrity auditing protocol based on the strong RSA assumption, and extend it to enable a third party auditor to audit client's data without learning the data content. Then we further extend our auditing protocol to support the data dynamic operations (modification, insertion and deletion), which achieves high security level in the standard model. At last we prove the security and justify the performance of our proposed protocol through concrete experiments and comparisons with the state of the art.
|
2022-12-28T14:39:01.308Z
|
242,541,393 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.31235/osf.io/y7wef",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "GREEN",
"url": "https://osf.io/y7wef/download"
}
|
This study aims to evaluate relationships between employees' subjective and mental health and non-regular employment. I use three-wave (2012, 2015, and 2018) from the Korean Youth Panel data to access relationships between health indicators and non-regular employment. I also explore gender differences to access if relationships between health and employment are different for the two sexes. I utilized the random-effects model to estimate the association between health indicators and non-regular employment across three waves. I found that mental health indicators rather than subjective health affect one’s odds of attending a temporary job. Also, the transition or maintenance of temporary positions showed that mental health indicators were associated with the transition from regular to a temporary job but were not associated with the maintenance of temporary positions. Additional analysis showed men were more likely to attend a temporary job if they had suicidal thoughts, while women were more susceptible to daily stress, despair, and suicidal thoughts altogether. I discuss the implications of this study for research and policy on non-regular employment's influence on youth’s health.
|
2022-01-27T08:11:05.088Z
|
153,468,082 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1093/ERAE/2.1.23",
"MAG": "2028056178",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Summary A computer-based method of examining students in farm management and agricultural economics is outlined.
|
2022-02-09T02:20:45.845Z
|
143,968,873 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1017/S0047279408002675",
"MAG": "2022829239",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Advocating the rethinking of the concept of the ageing workforce, especially through the lifecourse perspective, Chapter 7 (Donald Hirsch) draws upon the findings of Joseph Rowntree Foundation’s Transitions After 50 programme to suggest two agendas for the future. First, the extension of the concept of ‘career’ from a neatly planned sequence of professional progression for well-educated workers to a way of thinking about lifetime job opportunities for everybody. Second, a change in approach to occupational well-being that addresses the underlying causes of stress and how other forms of ill health affect how we conduct our working lives. Chapters 8 (Amanda Griffiths) and 9 (Wendy Loretto et al.), present a detailed treatment of some of the routes to extending working lives. While the former examines the importance of occupational health in ensuring a healthy and active workforce across the life course, the latter profiles the current patterns of flexible working among the over-50s in Great Britain to conclude that opportunities for working flexibility are currently limited. The next two chapters make compulsory reading to academics in the field of labour studies and social gerontology. Chapter 10 (Tony Maltby) focuses on older workers who are outside the labour market, and reports on EU-funded action research to discuss the fundamental practical issues of getting older people back to work. It concludes that although the supply side of the employment equation is widely and formally supported through a number of measures, little localised or targeted support or advice exists for employers of the positive benefits of recruiting workers over 50 years of age and of the demographic imperatives for such transitions. Chapter 11 (Chris Phillipson) conducts a critical review of the options for extending working lives whilst also paying attention to the heterogeneity of circumstances, attitudes and desires of older workers, and posing the question of whether we should simply accept the extending working life agenda. The author asks readers to consider seriously that the assumption of living longer does not necessarily mean retiring later, and that many people may still want to embrace a ‘culture of retirement’ even if it means a ‘trade-off’ with a lower standard of living. The final chapter, authored by the editors, contain a detailed consideration of the future prospects for older workers whilst also documenting the roles of workers, employers and the government in extending working life. The Future for Older Workers is an eminently readable and accessible book, and will be warmly welcomed by academics, students, policy makers and other professionals (such as training managers, HR professionals and trade unionists) and researchers interested in the coming of the ageing workforce. I found it extremely interesting, thought provoking and a comprehensively referenced text. The only hitch, of course, is its price. At £65.95, the book is surely out of reach for the undergraduate student, as well as scholars from lowand middleincome countries. This is lamentable as the publication is currently one of the best attempts to focus upon various measures taken by the state and employers to foster the employment of older workers. It would be a pity, given its price, to assign this book a place solely in libraries rather than on individuals’ bookshelves. marvin formosa University of Malta
|
2022-02-09T07:14:33.674Z
|
250,909,673 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1070/RC1969v038n09ABEH001835",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The problem of the extent to which the hydrodynamic and optical behaviour of chain molecules in solutions can be used for the observation and the quantitative assessment of their rigidity and of the internal ordering of their structures is examined. The general theoretical positions are illustrated by experimental results for a series of polymers, the molecules of which have a rigid chain structure. There is a bibliography of 106 references.
|
2022-07-31T02:20:10.018Z
|
42,894,888 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1021/ACSMEDCHEMLETT.6B00270",
"MAG": "2534906215",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
2'-α-C-Methyl-2'-β-C-fluorouridine and its phosphoramidate prodrugs were synthesized and evaluated for their inhibitory activity against HCV. The structure-activity relationship analysis of the phosphoramidate moiety found that 17m, 17q, and 17r exhibit potent activities against HCV, with EC50 values of 1.82 ± 0.19, 0.88 ± 0.12, and 2.24 ± 0.22 μM, respectively. The docking study revealed that the recognition of the 2'-β-F by Arg158, 3'-OH by N291, and the Watson-Crick pairing with the template allowed 23 to form the in-line conformation necessary for its incorporation into the viral RNA chain.
|
2022-09-15T05:00:02.730Z
|
244,957,168 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3389/fnins.2021.789583",
"MAG": null,
"PubMedCentral": "8695973"
},
"license": "CCBY",
"status": "GOLD",
"url": "https://www.frontiersin.org/articles/10.3389/fnins.2021.789583/pdf"
}
|
The Dmrt genes encode the transcription factor containing the DM (doublesex and mab-3) domain, an intertwined zinc finger-like DNA binding module. While Dmrt genes are mainly involved in the sexual development of various species, recent studies have revealed that Dmrt genes, which belong to the DmrtA subfamily, are differentially expressed in the embryonic brain and spinal cord and are essential for the development of the central nervous system. Herein, we summarize recent studies that reveal the multiple functions of the Dmrt genes in various aspects of vertebrate neural development, including brain patterning, neurogenesis, and the specification of neurons.
|
2022-10-30T17:19:44.683Z
|
219,057,169 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1177/2158244020914580",
"MAG": "3023406923",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://doi.org/10.1177/2158244020914580"
}
|
This study examined how internet-based communication channels impact on national security in Nigeria. The study was conducted in Enugu State, South East Nigeria. Three research questions guided the study and three null hypotheses were tested at .05 level of significance. A total of 385 internet users were selected using a combination of purposive and snow ball sampling techniques. In the analysis of data for the study, correlation analysis and multiple regression were used. The result of the analysis showed that internet-based media of communication like the Facebook, Gmail, YouTube, Yahoo mail, and Twitter significantly correlate national security. It was also found that there are specific ways through which negative use of the internet could impact negatively on national security. Such predictors include using internet-based media to recruit agents of national security challenges, to finance such efforts, to radicalize such agents, to train such agents, and to spread incitement that may be inimical to national security. It was also found that internet-based media could be useful for creating awareness on national security threats, raising alarm on national security issues, and making people alert on national security issues. Base on the result of this study, the researcher recommends, among others, that the traditional media like radio, TV, newspapers, and magazines should form a synergy with security agencies on how to create awareness to Nigerians regarding how security alertness for the overall benefit of national security.
|
2022-11-04T01:12:57.968Z
|
7,777,502 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1136/bmj.1.5593.679",
"MAG": "2015794428",
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://www.bmj.com/content/1/5593/679.full.pdf"
}
|
The switchover from foetal to adult haemoglobin synthesis, which is normaly complete by the end of the first year of life, is accompanied by marked changes in the red cell enzyme pattern. In particular, the level of carbonic anhydrase, which is very low in cord blood, rapidly increases during the first year of life to become the most abundant of the red cell non haemoglobin proteins. There have been occasional reports of the presence of increased levels of foetal haemoglobin in the red cells of patients with leukaemia (Beaven et al., 1960; Shuster et al., 1960; Hardisty et at., 1964; Weatherall and Walker, 1965). While a slight rise of foetal haemoglobin is not uncommon in a variety of leukaemias, very high levels have been noted only in patients with erythroleukaemia (Beaven et al., 1960) and in children with juvenile myeloid leukaemia (Hardisty et al., 1964). The occurrence of associated changes in red cell enzyme levels has not been noted. This report describes the changes in haemoglobin and red cell enzyme patterns over a 12-month period in a child with the clinical features of juvenile myeloid leukaemia and similar studies on 27 children with other types of leukaemia. These studies shed further light on the pathogenesis of juvenile chronic myeloid leukaemia.
|
2022-12-10T08:59:10.327Z
|
51,881,141 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ICC.2018.8422876",
"MAG": "2887886076",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Fuel cells are promising power sources for green data centers thanks to its high energy-efficiency, low greenhouse gas emissions and high reliability. However, fuel cells have a unique feature called limited load following, i.e., they are slow in adjusting power supply due to mechanical limitation of fuel delivery. When power demand of data centers suddenly grows, fuel cells would fail to provide sufficient power supply. On the other hand, fuel cells are slow to reduce its power supply when demand decreases, leading to energy waste. In this paper, we study to mitigate the impact of limited load following by associating a set of heterogeneous batteries with fuel cells. These batteries with different characteristics (e.g., capacity, charging and discharging rate) can power data centers when the energy supply of fuel cells is insufficient. They are charged by excessive power supply when demand decreases. Given future power demand, we formulate the energy management problem as a mixed-integer nonlinear programming. An online algorithm is designed to solve the problem without future knowledge. We conduct extensive simulations using real-world traces and results show that our proposed algorithm significantly outperforms existing solutions.
|
2022-12-27T20:54:23.532Z
|
237,244,723 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ITC-Egypt52936.2021.9513886",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Recently, the field of laser radiation detection LRD has witnessed a great development in the past three decades; there has been a great development in the field of semiconducting devices and optical systems to achieve high-performance LRD. Many important applications mainly depend on LRD in Civilian and military fields, like LIDAR systems, remote sensing, optical fiber communication system, and in military application laser-guided bomb LGB and laser warning receiver LWS. In all these applications, the laser sensors are chosen according to the requirements of the application in terms of sensitivity, a field of view, and the speed of the sensor's response in terms of converting the optical signal into electrical. In this paper, three-channel dichroic beam splitters, sky cameras, and a main optical system are utilized to identify the wavelengths of the incident laser radiation in the far-field. The optical system is designed to give a high-quality monochromatic image of LIDAR receivers and neglect a background noise from sunlight. The main contribution of This optical system is to reduce the electronic components and increase the optical components to enhancement the signal-to-noise ratio to achieve more than 50 dB in clear weather conditions of a LIDAR receiver by using the dichroic beam splitter technique with a sky cameras detector.
|
2022-12-10T13:33:29.648Z
|
37,036,045 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1212/01.WNL.0000031796.52748.A5",
"MAG": "2056808217",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Objective: To assess the knowledge of stroke risk factors and warning signs in a representative statewide sample of Michigan adults. Method: Respondents to the 1999 Michigan Behavioral Risk Factor Survey, a random-digit-dialed statewide survey of >2,500 adults, were asked to report up to three risk factors and warning signs for stroke. Predictors of inadequate knowledge (defined as not reporting any correct responses) of stroke risk factors and warning signs were identified using multiple logistic regression. Results: Eighty percent reported at least one correct risk factor for stroke, and 28% reported three. The most frequently mentioned risk factors were hypertension (32%), smoking (29%), and physical inactivity (26%). Sixty-nine percent reported at least one correct warning sign of stroke, but only 14% reported three. The most frequently mentioned warning signs were sudden weakness or numbness (46%) and sudden slurred speech, disorientation, or difficulty understanding (30%). Predictors for inadequate knowledge of both stroke risk factors and warning signs were similar and included age, race, sex, education, hypertension, and smoking. Conclusions: Knowledge of stroke risk factors and warning signs was moderate at best. One in five respondents was not aware of any stroke risk factors, and almost one in three was not aware of any stroke warning signs. Stroke knowledge was poorest among groups that have the highest risk of stroke.
|
2023-01-02T04:06:54.495Z
|
242,747,339 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5149/northcarolina/9781469653822.003.0001",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Describes how Those Who Know Don’t Say uses the NOI as a vehicle to explore forgotten sites and forms of Black struggle that confronted the carceral state during the mid-twentieth century. Reconsidering the place and scope of the NOI within the history of the Black Freedom Struggle in this way expands the boundaries of Black liberation struggles by revealing a more dynamic freedom movement in which objectives and strategies were always contested and debated within communities themselves, changing who we see as political theorists and agents of change, and expanding our spatial lens to include prison yards and courtrooms as sites of activism.
|
2022-01-23T03:18:43.726Z
|
243,962,775 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3406/bsef.2017.29392",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Résumé. – Depuis quelques années, surtout sur divers sites internet concernant la région africaine et malgache, les rapports se multiplient, qui nous font reconnaître, à l’aide des photos, les chenilles de l’espèce de Sphinx Coelonia fulvinotata (Butler, 1875), fréquemment confondues avec celles de Sphinx tête de mort, Acherontia atropos (Linné, 1758), qui leur ressemblent considérablement et qu'on peut souvent trouver sur les mêmes plantes. En considérant les informations connues et nouvelles, un inventaire des plantes sur lesquelles les chenilles de cette espèce ont été signalées jusqu'à présent est proposé, essayant d'ajouter quelques conclusions sur leur mode de vie, que ces informations peuvent éventuellement nous révéler.
|
2022-02-07T20:09:32.012Z
|
108,466,649 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/MOP.21886",
"MAG": "2024155425",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A multiple‐grating artificial microwave volume hologram (AMVH) is presented, which is designed based on the idea of multiply‐exposed optical holograms and is realized using printed artificial dielectric technique. It consists of a 3D conducting disk array formed by cascading a finite number of planar disk lattices and has its disk size varying in both the transverse (x) and normal (z) directions to simulate an effective 2‐D holographic grating. The reconstructed beams from such a multiplex AMVH are analyzed and a low cross‐talk between gratings is obtained. Comparison with the measured results on the fabricated multiplex AMVH prototype has confirmed the design and simulation. © 2006 Wiley Periodicals, Inc. Microwave Opt Technol Lett 48: 2179–2184, 2006; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.21886
|
2022-03-26T09:41:38.529Z
|
53,370,254 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.5539/JFR.V5N3P72",
"MAG": "2400516403",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Teff-oat composites were developed using gluten free teff flour containing essential amino acids with oat products containing beta-glucan known for lowering blood cholesterol and improving texture. The teff-oat composites were used in sugar cookies for improving nutritional and physical properties. Teff and its composites had higher water holding capacities compared to wheat flour. The pasting properties were not significantly influenced by 20% oat product replacements in teff-oat composites. The pasting viscosities of teff-OBC and teff-WOF 4:1 composites were similar to teff flour, but they were all higher than wheat flour. The elastic properties of teff-OBC (oat bran concentrate) and teff-WOF (whole oat flour) doughs were slightly higher than teff dough. Differences were also found in geometrical and textural properties of the doughs and cookies. Overall, the teff-oat cookies were acceptable in colour, flavour, and texture.
|
2022-07-09T06:03:35.223Z
|
51,971,262 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ISVLSI.2018.00114",
"MAG": "2885620418",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Extreme Electromagnetic Interference (EEMI) can cause device malfunction due to reparable upsets before any permanent hardware damage occurs to electronic devices. In this paper, a predictive model is developed to characterize the impact of EEMI on Metal-Oxide Semiconductor Field-Effect Transistors (MOSFETs) prior to any such permanent damage. The predictive model determines the onset of tolerance limits of EEMI on the Ion/Ioff ratio of a MOSFET for a given technology node, using only the most fundamental device parameters - such as the threshold voltage and power supply. The developed model is successfully compared against measurement data from a device fabricated using 350nm standard CMOS process through TSMC. Based on the predictive model the tolerance of the EEMI injected power in a MOSFET reduces due to technology scaling, starting from 9.7dBm at 350nm, and down to -1.7dBm at 65nm technology node.
|
2022-03-11T11:07:30.351Z
|
55,972,834 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1108/IJSMS-10-02-2009-B007",
"MAG": "346798646",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
This article analyses how different configurations of stakeholders create opportunities for the production of popular TV sports contests. Based on qualitative methodologies, biathlon and cross-country skiing are used as contrasting cases. The paper concludes that the relative success of the International Biathlon Union is due to a favourable network position in relation to stakeholders. By comparison, the International Ski Federation suffers from a weak position within a dense stakeholder network.
|
2022-07-31T20:36:30.133Z
|
144,449,033 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/00201748308601993",
"MAG": "2023649089",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
An inquiry into the possibility that life‐after‐death be understood as waking from a shared dream into the real world. Attempts to outlaw the possibility that ‘really’ we are, e.g., vat‐brains are shown to lead to unwelcome, anti‐realist conclusions about either the world or consciousness. The unsatisfactory nature of empirically observable (Humean) causal connections suggests that real causes may be found beyond the world of our present experience. Though such a story cannot now be proved to be true, we are entitled to entertain it as a serious possibility. An attempt is made to say what life is like in the ‘Real World’, whether this be a spatial world like our present one or not, and what moral it holds for our present life. I suggest (like Plato) that there are many levels of waking, and that our ‘Real Self should not be identified simply with our present egos.
|
2022-09-13T12:37:47.812Z
|
110,582,176 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/9780470546413.CH38",
"MAG": "2218951323",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The effects of the distribution of power and ground vias in C4/BGA type of packages are studied. Two types of via distributions are evaluated. One type is that vias are concentrated in the core area. The other type is that vias are uniformly distributed across the package. The performances of power and ground supplies of packages are evaluated through their resonance characteristics, impedances and effective inductances. It is found that the lowest package resonant frequency is increased by adding power and ground vias in the package. It is also found that, there are no significant differences in the lowest resonant frequencies between the two types of via distributions, but the centered via distribution results in substantially lower effective inductance of the package.
|
2022-09-14T06:42:26.552Z
|
14,933,844 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3390/W8060257",
"MAG": "2444116201",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Regular monitoring of water quality is increasingly necessary to keep pace with rapid environmental change and protect human health and well-being. Remote sensing has been suggested as a potential solution for monitoring certain water quality parameters without the need for in situ sampling, but universal methods and tools are lacking. While many studies have developed predictive relationships between remotely sensed surface reflectance and water parameters, these relationships are often unique to a particular geographic region and have little applicability in other areas. In order to remotely monitor water quality, these relationships must be developed on a region by region basis. This paper presents an automated method for processing remotely sensed images from Landsat Thematic Mapper (TM) and Enhanced Thematic Mapper Plus (ETM+) and extracting corrected reflectance measurements around known sample locations to allow rapid development of predictive water quality relationships to improve remote monitoring. Using open Python scripting, this study (1) provides an openly accessible and simple method for processing publicly available remote sensing data; and (2) allows determination of relationships between sampled water quality parameters and reflectance values to ultimately allow predictive monitoring. The method is demonstrated through a case study of the Ozark/Ouchita-Appalachian ecoregion in eastern Oklahoma using data collected for the Beneficial Use Monitoring Program (BUMP).
|
2022-11-25T00:49:49.883Z
|
253,514,288 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.47750/pnr.2022.13.s06.413",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://pnrjournal.com/index.php/home/article/download/2386/2051"
}
|
Neck and arm pain is common in the general population.1,2 Individuals with neck and upper extremity symptoms demonstrate greater levels of disability than do individuals with neck pain alone.3 While individuals with cervical radiculopathy often report neck pain, they most frequently seek treatment due to arm pain.3–5 Individuals with whiplash associated disorders who demonstrate signs of irritation of the brachial plexus and subsequent neck and arm pain reported more severe symptoms and achieved worse outcomes than those without brachial plexus irritation.6 Some authors have suggested that patients with neck and arm pain should be treated more expeditiously in order to avoid the further negative impact on mental health status associated with chronic symptoms.
|
2022-11-23T18:06:00.755Z
|
122,147,674 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1088/0031-8949/2011/T145/014080",
"MAG": "2054392376",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Non-destructive examination followed by high-heat-flux testing was performed for different small- and medium-scale mock-ups; this included the most recent developments related to actively cooled tungsten (W) or carbon fibre composite (CFC) armoured plasma-facing components. In particular, the heat-removal capability of these mock-ups manufactured by European companies with all the main features of the ITER divertor design was investigated both after manufacturing and after thermal cycling up to 20 MW m−2. Compliance with ITER requirements was explored in terms of bonding quality, heat flux performances and operational compatibility. The main results show an overall good heat-removal capability after the manufacturing process independent of the armour-to-heat sink bonding technology and promising behaviour with respect to thermal fatigue lifetime under heat flux up to 20 MW m−2 for the CFC-armoured tiles and 15 MW m−2 for the W-armoured tiles, respectively.
|
2022-12-15T19:12:18.567Z
|
239,703,392 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.47197/retos.v43i0.87285",
"MAG": "3196910998",
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "https://recyt.fecyt.es/index.php/retos/article/download/87285/65776"
}
|
Investigaciones demuestran que estudiantes universitarios de Pedagogía en Educación Física presentan mejores parámetros de condición física, sin embargo, es poca la información disponible sobre comportamiento de movimiento de 24 horas, medidas de manera objetiva. El objetivo de la presente investigación es describir conducta sedentaria, AF y patrones de sueño; determinar si existen diferencias significativas entre estudiantes según sexo y año que se encuentran cursando en la universidad; y determinar si existe asociación entre intensidad de AF y patrones de sueño. Se trabajó con una muestra de 128 estudiantes, en los cuales se evaluó de manera objetiva conducta sedentaria, AF de intensidad ligera, moderada y vigorosa, y patrones del sueño (tiempo de sueño, tiempo en cama y eficiencia del sueño). Los resultados indican que los estudiantes de primer año presentan para las tres intensidades de AF, los valores más altos de minutos promedio por día (hombres: ligera= 71.5 min, moderada= 100.4 min, vigorosa= 12 min; mujeres: ligera= 80.3 min, moderada= 93.8 min, vigorosa= 6.5 min), además de presentar menor tiempo de sueño, sin embargo, su eficiencia del sueño es más alta. En conclusión, los estudiantes de primer año presentan menor tiempo de conducta sedentaria, mayor cantidad de AF en las tres intensidades y menor tiempo de sueño, pero mayor eficiencia. Al comparar por sexo, las mujeres presentan menor cantidad de AF de intensidad moderada y vigorosa. AF de intensidad ligera se asoció con los patrones del sueño evaluados.
Abstract. Research shows that university students of Pedagogy in Physical Education present better parameters of physical condition, however, little information is available on sedentary behavior, physical activity (PA) and sleep patterns measured objectively. The objective of this research is to describe sedentary behavior, PA and sleep patterns; determine if there are significant differences between students according to sex and year of admission to university; and determine if there is an association between PA intensity and sleep patterns. We worked with a sample of 128 students, in which sedentary behavior, PA of light, moderate and vigorous intensity, and sleep patterns (sleep time, time in bed and sleep efficiency) were objectively evaluated. The results indicate that first year students present the highest values of average minutes per day for the three PA intensities (men: light = 71.5 min, moderate = 100.4 min, vigorous = 12 min; women: light = 80.3 min, moderate = 93.8 min, vigorous = 6.5 min), in addition to having less sleep time, however, their sleep efficiency is higher. In conclusion, first-year students present less time of sedentary behavior, greater amount of PA in the three intensities and less time of sleep, but greater efficiency. When comparing by sex, women present less PA of moderate and vigorous intensity. Light intensity PA was associated with assessed sleep patterns.
|
2022-01-27T08:55:07.627Z
|
208,868,253 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1515/pz-2019-0012",
"MAG": "2986786762",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Abstract The phenomenon of depositing various types of goods was practiced in Europe across the annals of all time. Known from the Bronze Age and in some regions of the continent, also from the Early Iron Age, metal object hoards are one of the most spectacular and easiest for identification as well as the most often recorded and analyzed illustration of this phenomenon. In being a specific category of archaeological finds in many respects – as far as the meaning of these practices in the culture of prehistoric communities, as well as the circumstances of their discovery – they were for many decades investigated in a particular way. In this context, unusually high emphasis was placed on typological analysis and the dominant forms of research were regional monographs. The resulting impasse of using limited data for the purposes of argumentation in favour of one of the hypotheses (sacral or profane) was underscored in the literature many a time. Both the development of archaeology and the significant growth of the number of newly discovered metal artefact assemblages, leads one to considerations over the appropriate means for conducting research on these enigmatic finds. The past few years have brought a series of new research propositions in respect to the means of investigating and interpreting this very phenomenon. The hoard from Rosko one could argue is not only worth exemplification on account of the significant research information it brings, but also as a means of indicating how research on hoards may be conducted.
|
2022-01-27T12:03:35.763Z
|
166,067,109 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.22029/KO.2018.231",
"MAG": "2901158898",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Der Sammelband Social Inequalities and Discontent in Yugoslav Socialism, der als Teil der Reihe Southeast European Studies von Routledge veroffentlicht wurde, nimmt einige neuralgische Punkte des mittleren und spaten jugoslawischen Sozialismus wieder auf. Die Autor_innen setzen sich mit den Studien von damaligen jugoslawischen Soziologen auseinander und reichern ihre Arbeit weiterhin mit selbst erschlossenen qualitativen Quellen an. Diese behandeln die soziale Stratifikation und Reproduktion von Ungleichheiten bezuglich Bildung, Wohnraum, Ethnizitat, Gender, Migration, politscher Macht(losigkeit) und Konsummacht. Obwohl die einzelnen Artikel teilweise nur lose verbunden erscheinen, verspricht die Vielfalt des Buches hinsichtlich der Disziplinen der Beitragenden sowie der angesprochenen Themen einen Erkenntnisgewinn sowohl fur erfahrene Wissenschaftler als auch fur Studienanfanger, die sich fur das sozialistische Jugoslawien interessieren.
|
2022-02-08T19:38:57.317Z
|
94,500,661 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/APMC.1985.051340112",
"MAG": "1694282286",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Pyrolysis and burning experiments were carried out with polypropylene, polystyrene and mixtures of them with cellulose. Polycyclic aromatic hydrocarbons (PAH) were extracted from the soot formed, and the extracts were examined by gas chromatography. The gas chromatograms were compared, like fingerprints, using a computer program developed for this purpose. The amount of benzo(a)pyrene was determined. The pyrolysis of the mixtures was also followed up by thermogravimetry. Under the experimental conditions the mixing of cellulose with hydrocarbon polymers (1:1 w/w) had only a small effect on the products formed during pyrolysis and combustion as compared with the treatment of the corresponding pure compounds.
Experimente zur Pyrolyse und Brennbarkeit wurden mit Polypropylen, Polystyrol und Mischungen dieser Polymeren mit Cellulose durchgefuhrt. Aus dem gebildeten Rus wurden polycyclische aromatische Kohlenwasserstoffe extrahiert und gaschromatographisch analysiert. Die Gaschromatogramme wurden mit einem zu diesem Zweck entwickelten Computerprogramm wie Fingerabdrucke verglichen. Der Gehalt an Benzo(a)pyren wurde bestimmt. Die Pyrolyse der Mischungen wurde auch thermogravimetrisch verfolgt. Unter experimentellen Bedingungen hat das Mischen von Cellulose mit polymeren Kohlenwasserstoffen (1 : 1 w/w) nur einen geringen Einflus auf die wahrend der Pyrolyse gebildeten Produkte, verglichen mit der Behandlung der entsprechenden reinen Komponenten.
|
2022-02-10T16:12:21.076Z
|
35,699,675 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/ENT.2016.022",
"MAG": "2574372752",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
A model of an X-band transmit-receive module was developed that was designed for definition of requirements to characteristics of an interconsistent set of monolithic microwave integrated circuits. The description of the model structure and the criteria for optimization of characteristics of MMIC included in the transmission and reception channels are given. The results of simulation of characteristics of MMIC included in the TRM are presented.
|
2022-02-12T08:12:14.691Z
|
142,295,349 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.22439/ASCA.V40I1-2.4684",
"MAG": "582189404",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The article discusses the academic and cultural relationships between Sweden and the U.S in the early 20th century. It focuses on the activities of two key institutions, the Sweden-America Foundation in Stockholm and the American-Scandinavian Foundation in New York. Both foundations were established in the second decade of the 20th century and sought to promote educational and cultural exchanges and contacts between Sweden and the United States. Although the foundations had similar goals, the reasons behind their establishment were quite different. The American foundation had one root in the development of Scandinavian-American ethnic communities. Another source of origin can be traced to a growing interest in medieval England, Old English, and Anglo-Saxon in American universities, in which Scandinavia came to occupy a privileged position. The Swedish foundation was established partly as a result of a Swedish cultural and academic reorientation following World War I, away from Germany towards the U.K. and the U.S. The effects of the work of both foundations have been significant, both in establishing close academic contacts between Sweden and the U.S. and in creating improving and promoting closer cultural and political ties between the two countries.
|
2022-09-08T12:29:46.024Z
|
239,298,073 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.31533/pubvet.v15n09a920.1-5",
"MAG": null,
"PubMedCentral": null
},
"license": "CCBY",
"status": "GOLD",
"url": "http://www.pubvet.com.br/uploads/40ab373d76993275108f6816d9522abb.pdf"
}
|
As hérnias umbilicais são muito comuns em cães, uma complicação frequente desta anomalia quando a hérnia se torna muito grande é o encarceramento ou estrangulamento de alças intestinais. Foi atendido na Clínica Escola Veterinária Prof. Marcos Vinicíus Tranquilim (CEVET), da Universidade Estadual do Centro-Oeste (UNICENTRO) um cão, macho com aproximadamente oito meses de idade apresentando fístula intestinal congênita em região de hérnia umbilical. Logo após o atendimento o animal foi encaminhado para o procedimento cirúrgico, o qual foi realizado com sucesso e o animal recuperou-se completamente. A realização do procedimento cirúrgico imediato foi de grande importância para a recuperação do paciente, uma vez que ainda não havia derrame de conteúdo fecal na cavidade abdominal.
|
2022-10-14T01:01:07.423Z
|
145,610,654 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1111/j.1475-6757.1980.tb00791.x",
"MAG": "2152451729",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
NTIL recently Vergd’s influence on Spenser was considered extensive but not particularly profound. Despite the debts to Vergil acknowledged by both E. K. and Spenser himself and over three centuries of annotation, most critics agreed with Merritt Hughes: echoes of the Amid in The Faerie Queene are “memories of a time-hallowed but timedimmed reverence.” 1 Later critics have seen Vergil’s influence as leading to serious imitation based on a “radically” different perception of the Aenkd’s “intention and method.” 2 The present essay will explore this difference by demonstrating how Spenser’s “misreading” (by later standards) leads to a method of epic composition itself both more ancient and more radical than has been recognized. Primarily Spenser views Aeneas not as an abstract moral paradigm but, in a tradition from the earliest Vergd commentators, as an exemplification of virtues. This method of a plural Aeneas Spenser directs in his epic toward his contemporary generation of courtiers; it will offer young men (and women) new possibilities for human nature, actively ethical (vinrrn) and political ( a m ) . The result of such reading is that in Spenser’s epic Aeneas becomes more heuristic method than statuesque
|
2022-09-27T14:59:37.436Z
|
252,106,276 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.35848/1347-4065/ac8f52",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": "BRONZE",
"url": "https://iopscience.iop.org/article/10.35848/1347-4065/ac8f52/pdf"
}
|
The Gd thickness dependence of spin–orbit torque (SOT) and critical current density of SOT switching in ferrimagnetic Gd/FeCo multilayers grown on a Ta seed layer was investigated and compared with the results on GdFeCo alloy/Ta bilayers. Critical current density of SOT switching J sw of Gd/FeCo multilayers was almost the same as those of the GdFeCo alloy films. The magnitudes of damping-like and field-like SOT effective fields, H DL and H FL, respectively, in Gd/FeCo multilayers were confirmed to increase near the compensation point, and the sign of H FL in Gd/FeCo multilayers was confirmed to change across the compensation point as well as GdFeCo alloy. Damping-like and field-like SOTs, estimated by multiplying the SOT effective fields by net magnetization, exhibited slightly smaller values for TM-dominant Gd/FeCo than for TM-dominant GdFeCo, while RE-dominant Gd/FeCo shows almost the same SOTs as RE-dominant GdFeCo.
|
2022-12-10T09:47:49.775Z
|
95,155,126 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1116/1.568798",
"MAG": "1990079174",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
During the past decade, since commercial instruments have become available, secondary−ion mass spectrometry has been increasingly applied as a very sensitive technique for surface characterization. Depth−concentration profiling has emerged as one of the most important applications, owing to the high−depth resolution obtainable. The intrinsic depth resolution of some 10 A is degraded by uneven erosion, sample mixing owing to the atomic collisions, and at very low concentration, profiling by the sample consumption required. Quantitative analyses are more difficult than with other techniques, but are feasible. The utilization of chemical signal enhancement by oxygen flooding or oxygen bombardment is very helpful.
|
2022-12-14T10:00:23.321Z
|
102,678,700 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/aenm.201702337",
"MAG": "2777870289",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Driven by increasing demand for high‐energy‐density batteries for consumer electronics and electric vehicles, substantial progress is achieved in the development of long‐life lithium–sulfur (Li–S) batteries. Less attention is given to Li–S batteries with high volume energy density, which is crucial for applications in compact space. Here, a series of elastic sandwich‐structured cathode materials consisting of alternating VS2‐attached reduced graphene oxide (rGO) sheets and active sulfur layers are reported. Due to the high polarity and conductivity of VS2, a small amount of VS2 can suppress the shuttle effect of polysulfides and improve the redox kinetics of sulfur species in the whole sulfur layer. Sandwich‐structured rGO–VS2/S composites exhibit significantly improved electrochemical performance, with high discharge capacities, low polarization, and excellent cycling stability compared with their bare rGO/S counterparts. Impressively, the tap density of rGO–VS2/S with 89 wt% sulfur loading is 1.84 g cm−3, which is almost three times higher than that of rGO/S with the same sulfur content (0.63 g cm−3), and the volumetric specific capacity of the whole cell is as high as 1182.1 mA h cm−3, comparable with the state‐of‐the‐art reported for energy storage devices, demonstrating the potential for application of these composites in long‐life and high‐energy‐density Li–S batteries.
|
2023-01-01T06:34:30.450Z
|
136,535,821 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1117/12.967215",
"MAG": "2119599811",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In a previous paper, we presented general eigenvalue equations for both transverse-electric (TE) and transverse-magnetic (TM) modes in multilayer slab waveguides. Here, those formulas are applied to symmetric periodic stratified media. The results obtained are compared with those of Yeh et al,2 which were obtained by using matrix method. The eigenvalue equations for even and odd-modes are also obtained.
|
2022-01-27T02:05:33.084Z
|
208,321,505 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.3760/cma.j.issn.2095-4352.2019.10.014",
"MAG": "3025553211",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
OBJECTIVE
To evaluate cerebrospinal fluid (CSF) vancomycin concentrations and identify factors influencing CSF vancomycin concentrations in critically ill neurosurgical patients.
METHODS
A retrospective study was conducted. Adult patients who received vancomycin treatment and CSF vancomycin concentrations monitoring admitted to neurosurgical intensive care unit (ICU) of the First Affiliated Hospital of Sun Yat-sen University from January 2016 to June 2019 were enrolled. General information, vancomycin dosing regimens, CSF vancomycin concentrations, CSF drainage methods and volume of the previous day, and concurrent medications, etc. were collected for analysis. CSF vancomycin concentrations of patients with definite or indefinite central nervous system (CNS) infection, different vancomycin dosing regimens and their influencing factors were analyzed.
RESULTS
A total of 22 patients were included. 168 CSF specimens were collected for culture, 20 specimens of which were culture positive, with a positive rate of 11.9%. Sixty cases of CSF vancomycin concentration were obtained. Among the 22 patients, 7 patients (31.8%) were diagnosed with proven CNS infection, 11 patients (50.0%) clinically diagnosed, 2 patients (9.1%) diagnosed with uncertain CNS infection, and 2 patients (9.1%) diagnosed without CNS infection. Intravenous (IV) administration of vancomycin alone was used in 15 cases (25.0%), intrathecal injection in 17 cases (28.3%), IV+intrathecal injection in 23 cases (38.3%), and IV+intraventricular administration in 5 cases (8.3%). The CSF vancomycin concentrations ranged from < 0.24 to > 100 mg/L, with an average level of 14.40 (4.79, 42.34) mg/L. (1) Administration methods of vancomycin affected CSF vancomycin concentrations. The CSF vancomycin concentration with intrathecal injection or intraventricular administration was higher than that of IV administration alone [mg/L: 25.91 (11.28, 58.17) vs. 2.71 (0.54, 5.33), U = 42.000, P < 0.01]. (2) When vancomycin was administered by IV treatment alone, CSF vancomycin concentrations were low in both groups with definite CNS infection (proven+probable) and indefinite CNS infection (possible+non-infection), the CSF vancomycin concentrations of which were 4.14 (1.40, 6.36) mg/L and 1.27 (0.24, 3.33) mg/L respectively, with no significant difference (U = 11.000, P = 0.086). (3) CSF vancomycin concentrations rose with the increased dose of vancomycin delivered by intrathecal injection or intraventricular administration. According to the dose of vancomycin administered locally on the day before therapeutic drug monitoring (TDM), cases were divided into the following groups: 0-15 mg group (n = 22), 20-35 mg group (n = 33), and 40-50 mg group (n = 5), the CSF vancomycin concentrations of which were 4.14 (1.09, 8.45), 30.52 (14.31, 59.61) and 59.43 (25.51, 92.45) mg/L respectively, with significant difference (H = 33.399, P < 0.01). Moreover, the cases of CSF vancomycin concentration of ≥ 10 mg/L accounted for 18.2%, 84.8% and 100% of these three groups, respectively. CSF vancomycin concentrations mostly reached target level when dose of vancomycin administered locally were 20 mg/L or more.
CONCLUSIONS
It is difficult to reach target CSF vancomycin concentration for critically ill neurosurgical patients with or without CNS infection by IV treatment. Local administration is an effective treatment regimen to increase CSF vancomycin concentration.
|
2022-02-08T03:53:51.102Z
|
96,418,632 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1246/CL.1982.123",
"MAG": "2037509638",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Methyl esters of 1,1-dithiodicarboxylic acids were formed by the reaction of cyclic ketones with lithium methoxide and carbon disulfide in tetrahydrofuran followed by the treatment with methyl iodide. The reaction proceeds via dithiocarboxylation and carbonyl carbon-carbon bond cleavage through an inverse Dieckmann-type reaction.
|
2022-09-01T08:35:26.106Z
|
72,215,429 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1001/ARCHSURG.1941.01210090047003",
"MAG": "2015319234",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
An important method of approach to the study of the value of preserved blood is an analysis of the results of transfusion of such blood. Just as some questions which arise as to the limitations of bank blood are answered by inquiry into the changes which occur in various components of blood when preserved, other, equally important questions, such as the effect of age of blood on the incidence and type of transfusion reactions, can be answered only by accurate recording of the results obtained from a long series of transfusions of bank blood. It is from this standpoint primarily that a statistical analysis of 3,077 consecutive transfusions of bank blood at the Cincinnati General Hospital becomes of interest. Numerous collateral points of interest which pertain to the practical operation of the service are also revealed by this study. These are of value to any one planning a similar organization
|
2022-09-09T03:00:54.520Z
|
198,913,155 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/ACM.0000000000002894",
"MAG": "2965329627",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Residency training program directors and teaching faculty invest an enormous amount of time, energy, and resources in providing underperforming at-risk learners with remedial teaching. A remediation program was created at the University of Colorado School of Medicine in 2006 and centralized in 2012 that consolidated expertise in and resources for learner assessment and individualized teaching for struggling learners, particularly those placed on probation or receiving letters of warning (called focused review letters) from their residency programs. Since the implementation of the program, the authors have observed a decrease in the number of residents being placed on probation and, of those on probation, more are graduating and obtaining board certification. In this Article, the authors aim to describe the development and outcomes of the program and to explore possible reasons for the improved outcomes.
|
2022-09-11T15:43:33.886Z
|
150,681,205 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.11644/KIEP.JEAI.2014.18.1.274",
"MAG": "75589877",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The purpose of this research is to identify the relation between OFDI (Outward Foreign Direct Investment) and wage inequality. In order to analyze various effects of OFDI on wages depending on the types of workers, the research classified laborers into four categories: permanent/skilled worker, permanent/unskilled worker, temporary/skilled worker, and temporary/unskilled worker. With controlling wage- determining factors such as education, labor union, individual fixed-effect, and industry-level effect, this paper examines whether OFDI attributes to the wage inequality among each type of workers. Moreover, this study also analyzes possible effects on wages that could vary according to the different characteristics of investments by classifying OFDI into two groups: OECD and non-OECD. The results reveal that OFDI makes certain differences according to skill-intensity and contract type in terms of influences on wages. It also shows that the effect of OFDI on wages is more subject to contract type than to skill-intensity. The classification of OFDI into OECD and non-OECD proves that effects on wages can vary by characteristics of the subject of investment.
|
2022-09-12T10:49:41.790Z
|
154,573,694 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/01495939508403033",
"MAG": "2076449201",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
At present, there exists clandestine proliferation of nuclear weapons in the Asia‐Pacific region. The nuclear proliferation may alter or even upset the current regional balance of power and disrupt the stability of the region. It may also lead to new military conflicts. During a regional conflict, one nuclear threshold state may use nuclear weapons against its adversary. Under these circumstances, the international community should devote its best efforts to eliminating the nuclear proliferation in the region. Before that final goal is reached, states in the region should seek to maintain the strategic stability of the region in the presence of nuclear proliferation. In order to achieve that objective, the Asia‐Pacific region should set up a model including multilateral security mechanisms and bilateral confidence‐ and security‐building measures.
|
2022-12-18T06:03:26.092Z
|
30,024,618 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/00071668908417134",
"MAG": "2145912461",
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},
"license": null,
"status": null,
"url": null
}
|
1. The increase in the numbers of yellow and of white ovarian follicles was studied from 10 weeks of age to sexual maturity in broiler breeder pullets fed ad libitum and on a restricted intake. The growth of follicles greater than 1 mm diameter commenced at 14 to 16 weeks of age in ad libitum birds and at 22 to 24 weeks in those which were restricted. 2. In a second experiment, groups of birds restricted from 4 d of age were transferred to ad libitum feeding at 2-week intervals and examined at first egg. The numbers of yellow follicles at first egg were not affected by restriction to 14 weeks of age but, thereafter, declined linearly with time on restriction. 3. In the second experiment there were no comparable responses in the numbers of white follicles or in the rates of atresia. 4. Food restriction to 22 weeks of age produced about half the response in numbers of yellow follicles as restriction continued to point of lay (27 to 32 weeks of age). In practical situations, the results suggest that food intake should be restricted up to the onset of lay and then increased in relation to the rise in egg production. 5. Atresia was greatest in white follicles 3.15 to 6.30 mm diameter and was less outside this range.
|
2022-12-18T01:59:12.131Z
|
2,203,163 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1097/01.HTR.0000314529.22777.43",
"MAG": "2021059523",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
ObjectiveTo compare the efficacy of 2 strategies, errorless learning (EL) and self-instruction training (SIT), for remediating emotion perception deficits in individuals with traumatic brain injury (TBI). DesignRandomized controlled trial comparing groups receiving 25 hours (across 10 weeks) of treatment with either EL or SIT with waitlist control. Setting and ParticipantsEighteen adult outpatient volunteers with severe TBI who were at least 6 months postinjury. Main Outcomes MeasuresPhotograph-based emotion recognition tasks, The Awareness of Social Inferences Test, and questionnaire measures, for example, the Sydney Psychosocial Reintegration Scale. ResultsBoth treatment groups showed modest improvement in emotion perception ability. Limited evidence suggests that SIT may be a favorable approach for this type of remediation. ConclusionsAlthough further research is needed, there are reasons for optimism regarding rehabilitation of emotion perception following TBI.
|
2022-12-20T00:31:55.792Z
|
122,972,727 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1002/PSSB.2221450232",
"MAG": "2074686833",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The task of the thermodynamics of “angle magnetic phase” is solved in the spin-wave approximation at finite temperatures by the parametrical Green's function (PGF) method. The theory application is illustrated by the low-temperature behaviour of the magnon heat capacity and magnetization of the rare-earth metals Tb and Dy. The received analytical dependences are in good agreement with the experimental data.
[Russian Text Ignored]
|
2022-02-09T18:50:52.554Z
|
43,567,572 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/EURCON.2009.5167858",
"MAG": "2104671547",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Notwithstanding on variety of existing processes of induction skull melting of oxides, electrical and thermal properties of oxides melts are practically unknown. From the other hand, liquid-phase synthesis of Hi-Tech oxides materials such as new ceramics, monocrystals and glasses, requires knowledge of melts properties up to 3700 K. Inasmuch as the main physical property, which influence to the melt power consumption at induction heating is electrical conductivity then study of electrical conductivity temperature dependence is necessary. The principle and technical realization of the electrical conductivity measurement of melts are presented. The approach is based on induction melting in cold crucible technology and inverse electromagnetic problem solution. Analysis of the method accuracy via input data errors is presented. For increasing of Ill-posed problem solution was used over determination of set of equations. Conductivity of lanthanum chromite melt composition La0,975Ca0,025CrO3 for the temperature up to 2873 K is shown too.
|
2022-02-12T02:00:08.658Z
|
20,699,215 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.4103/2224-3151.206767",
"MAG": "1595212231",
"PubMedCentral": null
},
"license": "CCBYNCSA",
"status": "GREEN",
"url": "https://apps.who.int/iris/rest/bitstreams/1087972/retrieve"
}
|
Veterinary public health (VPH) is ideally suited to promote convergence between human, animal and environmental sectors. Recent zoonotic and emerging infectious disease events have given rise to increasing calls for efforts to build global VPH capacities. However, even with their greater vulnerability to such events, including their economic and livelihood impacts, the response from low-and middle-income countries such as India has been suboptimal, thereby elevating global health risks. Addressing risks effectively at the human–animal interface in these countries will require a clear vision, consistent policies, strategic approach and sustained political commitment to reform and refine the current VPH capacity-building efforts. Only then can the discipline serve its goal of disease prevention, poverty alleviation and support for sustainable livelihoods through improvements in human and animal health.
|
2022-05-27T01:00:45.261Z
|
98,202,833 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1107/S1600536802010206",
"MAG": "2099163448",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
The structure of the title compound, C16H14N2O2S, comprises a twisted molecule with dihedral angles of 11.3 (2) and 45.8 (1)° between the thiazole and, respectively, the pyrrole and phenyl rings.
|
2022-06-03T12:27:12.881Z
|
250,564,595 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1149/ma2022-0114972mtgabs",
"MAG": null,
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Graphene Oxide Liquid Crystal (GOLC) is an emerging 2D carbon based soft material, which exhibits nematic type colloidal discotic liquid crystallinity with the orientational ordering of graphene oxide flakes in good solvents, including water. Since our first discovery of GOLC in aqueous dispersion at 2009, this interesting mesophase has been utilized over world-wide for many different application fields, such as liquid crystalline graphene fiber spinning, highly ordered graphene membrane/film production, prototype liquid crystal display and so on. Interestingly, GOLC also allow us a valuable opportunity for the highly ordered molecular scale assembly of functional nanoscale structures. This presentation will introduce our current status of GOLC research particularly focusing on the nanoscale assembly of functional nanostructures, including highly oriented 1D fibers, 2D films and 3D nanoporous structures. Besides, relevant research works associated to the nanoscale assembly and chemical modification of various low dimensional materials, including 1D carbon nanotubes, 2D TMDs and MXene, will be presented particularly aiming at energy and environmental applications. In the last part of presentation, our wold-first discovery of single atom catalyst will be introduced also, including other research efforts exploiting customized heteroelement doping of graphene based strucures.
|
2022-07-17T05:24:10.614Z
|
46,894,474 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1117/12.594781",
"MAG": "2591019076",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In present-day medical practice it is often necessary to nonrigidly align image data, either intra- or inter-patient. Current registration algorithms usually do not take different tissue types into account. A problem that might occur with these algorithms is that rigid tissue, like bone, also deforms elastically. We propose a method to correct a deformation field, that is calculated with a nonrigid registration algorithm. The correction is based on a second feature image, which represents the tissue stiffness. The amount of smoothing of the deformation field is related to this stiffness coefficient. By filtering the deformation field on rigid tissue, the deformation field will represent a local rigid transformation. Other parts of the image containing nonrigid tissue are smoothed less, which leaves the original elastic deformation (almost) untouched. It is shown on a synthetic example and on inspiration-expiration CT data of the thorax, that a filtering of the deformation field based on tissue type indeed keeps rigid tissue rigid, thus improving the registration results.
|
2022-09-14T18:32:28.139Z
|
53,575,057 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1504/IJLSM.2009.022499",
"MAG": "1967832922",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
We offer a shipper and a carrier the choice among three contracts in which to frame their relationship. Both can also take recourse in the transport spot market. Demand and price on the spot market are dependent exogenous stochastic processes. We model the outcome of this endogenous choice of contract. The results, given in closed form, are different from those presented in the literature. Using numeric instances, we show how a choice is made and which contract would be preferred. Comparison on the variance of the economic returns are offered. The conclusions are applicable when the carrier is not capacity constrained.
|
2022-09-13T09:14:56.326Z
|
21,829,929 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1109/CC.2013.6633742",
"MAG": "2019217084",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
In this paper, we propose a security-oriented transmission scheme with the help of multiple relays in Cognitive Radio (CR). To maximise the Secrecy Capacity (SC) of the source-destination link in CR, both beamforming and cooperative jamming technologies are used to improve the performance of the Secondary User (SU) and protect the Primary User (PU). The effectiveness of the proposed scheme is demonstrated using extensive simulation. Both theoretical analyses and simulation results reveal that the proposed scheme contributes to the secure transmission of the SU with acceptable attenuation of the Signal-to-Noise Ratio (SNR) at the PU receiver, and the upper bound of the SC at the SU receiver is able to exploit the power allocation strategy.
|
2022-12-10T22:18:23.965Z
|
98,586,618 |
{
"externalids": {
"ACL": null,
"ArXiv": null,
"DOI": "10.1080/02786820152546743",
"MAG": "2123423598",
"PubMedCentral": null
},
"license": null,
"status": null,
"url": null
}
|
Inhalation exposure to ultrafine particles, including radon progeny and other combustion aerosols, has been implicated in potential health risks of ambient and indoor environments. These particles deposit in the respiratory tract mainly by diffusion. The purpose of this study was to determine the deposition pattern of nanometer-sized particles in the human tracheobronchial (TB) airways of children and young adults. The deposition was determined for 1.75, 10, and 40 nm 212Pb particles at flow rates corresponding to respiratory minute volumes at rest and during moderate exercise. The 1.75 nm particles were unattached clusters, whereas the 10 and 40 nm particles were silver particles with attached 212Pb clusters. Replicate casts of the upper TB airways of 3, 16, and 23 year old humans were used, including the larynx, trachea, and bronchial airways down to generations 5-8. Deposition in each generation and total deposition were measured by counting the 212Pb gamma photopeak in a NaI (Tl) detector. The effects of airway geometry, particle size, and flow rate on deposition efficiency were studied. The deposition of the 1.75 nm particle, corresponding to unattached indoor radon progeny, was substantially higher than that of the 10 and 40 nm particles. The dependence of particle deposition on the flow rate was relatively weak, and deposition efficiencies were only slightly higher at the lower flow rates. The deposition models for diffusion from parabolic flow underestimated aerosol deposition, whereas the diffusion deposition predicted for plug flow overestimated the TB deposition. The deposition models resulting from this study can be used for developing lung deposition models and in the risk assessment of radon progeny and ultrafine ambient particles.
|
2022-12-14T08:53:36.897Z
|