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https://en.wikipedia.org/wiki/Pipe%20%28fluid%20conveyance%29
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A pipe is a tubular section or hollow cylinder, usually but not necessarily of circular cross-section, used mainly to convey substances which can flow — liquids and gases (fluids), slurries, powders and masses of small solids. It can also be used for structural applications; hollow pipe is far stiffer per unit weight than solid members.
In common usage the words pipe and tube are usually interchangeable, but in industry and engineering, the terms are uniquely defined. Depending on the applicable standard to which it is manufactured, pipe is generally specified by a nominal diameter with a constant outside diameter (OD) and a schedule that defines the thickness. Tube is most often specified by the OD and wall thickness, but may be specified by any two of OD, inside diameter (ID), and wall thickness. Pipe is generally manufactured to one of several international and national industrial standards. While similar standards exist for specific industry application tubing, tube is often made to custom sizes and a broader range of diameters and tolerances. Many industrial and government standards exist for the production of pipe and tubing. The term "tube" is also commonly applied to non-cylindrical sections, i.e., square or rectangular tubing. In general, "pipe" is the more common term in most of the world, whereas "tube" is more widely used in the United States.
Both "pipe" and "tube" imply a level of rigidity and permanence, whereas a hose (or hosepipe) is usually portable and
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https://en.wikipedia.org/wiki/Lactucin
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Lactucin is a bitter substance that forms a white crystalline solid and belongs to the group of sesquiterpene lactones. It is found in some varieties of lettuce and is an ingredient of lactucarium. It has been shown to have analgesic and sedative properties. It has also shown some antimalarial effects. It is also found in dandelion coffee.
It acts as an adenosine receptor agonist.
See also
Lactucopicrin
References
Sesquiterpene lactones
Primary alcohols
Secondary alcohols
Enones
Azulenofurans
Cyclopentenes
Lactones
Vinylidene compounds
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https://en.wikipedia.org/wiki/Bairstow%27s%20method
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In numerical analysis, Bairstow's method is an efficient algorithm for finding the roots of a real polynomial of arbitrary degree. The algorithm first appeared in the appendix of the 1920 book Applied Aerodynamics by Leonard Bairstow. The algorithm finds the roots in complex conjugate pairs using only real arithmetic.
See root-finding algorithm for other algorithms.
Description of the method
Bairstow's approach is to use Newton's method to adjust the coefficients u and v in the quadratic until its roots are also roots of the polynomial being solved. The roots of the quadratic may then be determined, and the polynomial may be divided by the quadratic to eliminate those roots. This process is then iterated until the polynomial becomes quadratic or linear, and all the roots have been determined.
Long division of the polynomial to be solved
by yields a quotient and a remainder such that
A second division of by is performed to yield a quotient and remainder with
The variables , and the are functions of and . They can be found recursively as follows.
The quadratic evenly divides the polynomial when
Values of and for which this occurs can be discovered by picking starting values and iterating Newton's method in two dimensions
until convergence occurs. This method to find the zeroes of polynomials can thus be easily implemented with a programming language or even a spreadsheet.
Example
The task is to determine a pair of roots of the polynomial
As first qu
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https://en.wikipedia.org/wiki/Tuberous%20sclerosis%20complex%20tumor%20suppressors
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Tuberous sclerosis complex (TSC) tumor suppressors form the TSC1-TSC2 molecular complex. Under poor growth conditions the TSC1-TSC2 complex limits cell growth. A key promoter of cell growth, mTORC1, is inhibited by the tuberous sclerosis complex. Insulin activates mTORC1 and causes dissociation of TSC from the surface of lysosomes.
Resistance to ischemia-reperfusion injury by protein restriction is mediated by activation of the tuberous sclerosis complex.
References
Genes on human chromosome 9
Genes on human chromosome 16
Tumor suppressor genes
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https://en.wikipedia.org/wiki/Wigner%20crystal
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A Wigner crystal is the solid (crystalline) phase of electrons first predicted by Eugene Wigner in 1934. A gas of electrons moving in a uniform, inert, neutralizing background (i.e. Jellium Model) will crystallize and form a lattice if the electron density is less than a critical value. This is because the potential energy dominates the kinetic energy at low densities, so the detailed spatial arrangement of the electrons becomes important. To minimize the potential energy, the electrons form a bcc (body-centered cubic) lattice in 3D, a triangular lattice in 2D and an evenly spaced lattice in 1D. Most experimentally observed Wigner clusters exist due to the presence of the external confinement, i.e. external potential trap. As a consequence, deviations from the b.c.c or triangular lattice are observed. A crystalline state of the 2D electron gas can also be realized by applying a sufficiently strong magnetic field. However, it is still not clear whether it is the Wigner crystallization that has led to observation of insulating behaviour in magnetotransport measurements on 2D electron systems, since other candidates are present, such as Anderson localization.
More generally, a Wigner crystal phase can also refer to a crystal phase occurring in non-electronic systems at low density. In contrast, most crystals melt as the density is lowered. Examples seen in the laboratory are charged colloids or charged plastic spheres.
Description
A uniform electron gas at zero temperature
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https://en.wikipedia.org/wiki/Green%20pig
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Green pig may refer to:
Fluorescent green pig, a transgenic pig expressing green fluorescent protein
The targets in the Angry Birds video game and franchise
A character in The Little Green Pig, a story within the play The Pillowman
A rath in the nonsense poem Jabberwocky
Magically created pigs in Disney Princess Enchanted Tales: Follow Your Dreams
A character in the Malazan Book of the Fallen
A minor character in the manga series Tonde Burin
Hawk's mother in The Seven Deadly Sins manga series
The cover of À la Carte, an album by Erste Allgemeine Verunsicherung
See also
Green pig-face, a flower
Last One Home is a Green Pig, a children's book by Edith Thacher Hurd
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https://en.wikipedia.org/wiki/98.7%20FM
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The following radio stations broadcast on FM frequency 98.7 MHz:
Argentina
Cristal in Olavarría, Buenos Aires
Cóndor in Villa de Merlo, San Luis
Del Mar in Comodoro Rivadavia, Chubut
Imperio in Río Cuarto, Córdoba
Estación K2 in Necochea, Buenos Aires
Las Rosas in Las Rosas, Santa Fe
LaRock-a in San Carlos de Bariloche, Río Negro
LIF in General Arenales, Buenos Aires
Magica Miramar in Miramar, Buenos Aires
Metro TDF in Río Grande, Tierra del Fuego
Municipal in Patquia, La Rioja
Nacional Folklórica in Buenos Aires
Tango in Rosario, Santa Fe
ToP! Radio in Camilo Aldao, Córdoba
Universidad in Posadas, Misiones
Universo in San Antonio de Arredondo, Córdoba
VOX in Tres Arroyos, Buenos Aires
Z98 Radio Laprida in Laprida, Buenos Aires
Australia
ABC Classic FM in Port Macquarie, New South Wales
SBS Radio in Young, New South Wales
4RGM in Mackay, Queensland
Ten FM in Stanthorpe, Queensland
5EZY in Renmark, South Australia
3RPP in Melbourne, Victoria
Radio National in Orbost, Victoria
SBS Radio in Mildura, Victoria
Triple J in Kalgoorlie, Western Australia
Brunei
KRISTALfm in Tutong and Kuala Belait
Canada (Channel 254)
CBCB-FM in Owen Sound, Ontario
CBCP-FM in Peterborough, Ontario
CBQX-FM in Kenora, Ontario
CBYM-FM in Mt. St. Margaret, Newfoundland and Labrador
CBYN-FM in Nelson, British Columbia
CHFB-FM in Bonnyville, Alberta
CHGR-FM in Grand Rapids, Manitoba
CHWN-FM in Skownan, Manitoba
CICF-4-FM in Enderby, British Columbia
CICV-FM in Cowi
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https://en.wikipedia.org/wiki/Theoretical%20motivation%20for%20general%20relativity
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A theoretical motivation for general relativity, including the motivation for the geodesic equation and the Einstein field equation, can be obtained from special relativity by examining the dynamics of particles in circular orbits about the Earth. A key advantage in examining circular orbits is that it is possible to know the solution of the Einstein Field Equation a priori. This provides a means to inform and verify the formalism.
General relativity addresses two questions:
How does the curvature of spacetime affect the motion of matter?
How does the presence of matter affect the curvature of spacetime?
The former question is answered with the geodesic equation. The second question is answered with the Einstein field equation. The geodesic equation and the field equation are related through a principle of least action. The motivation for the geodesic equation is provided in the section Geodesic equation for circular orbits. The motivation for the Einstein field equation is provided in the section Stress–energy tensor.
Geodesic equation for circular orbits
Kinetics of circular orbits
For definiteness consider a circular Earth orbit (helical world line) of a particle. The particle travels with speed v. An observer on Earth sees that length is contracted in the frame of the particle. A measuring stick traveling with the particle appears shorter to the Earth observer. Therefore, the circumference of the orbit, which is in the direction of motion appears longer than tim
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https://en.wikipedia.org/wiki/Cysteine%20protease
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Cysteine proteases, also known as thiol proteases, are hydrolase enzymes that degrade proteins. These proteases share a common catalytic mechanism that involves a nucleophilic cysteine thiol in a catalytic triad or dyad.
Discovered by Gopal Chunder Roy in 1873, the first cysteine protease to be isolated and characterized was papain, obtained from Carica papaya. Cysteine proteases are commonly encountered in fruits including the papaya, pineapple, fig and kiwifruit. The proportion of protease tends to be higher when the fruit is unripe. In fact, the latex of dozens of different plant families are known to contain cysteine proteases. Cysteine proteases are used as an ingredient in meat tenderizers.
Classification
The MEROPS protease classification system counts 14 superfamilies plus several currently unassigned families (as of 2013) each containing many families. Each superfamily uses the catalytic triad or dyad in a different protein fold and so represent convergent evolution of the catalytic mechanism.
For superfamilies, P indicates a superfamily containing a mixture of nucleophile class families, and C indicates purely cysteine proteases. superfamily. Within each superfamily, families are designated by their catalytic nucleophile (C denoting cysteine proteases).
{| class="wikitable"
|+Families of cysteine proteases
! Superfamily !! Families !! Examples
|-
| CA || C1, C2, C6, C10, C12, C16, C19, C28, C31, C32, C33, C39, C47, C51, C54, C58, C64,
C65, C66, C67, C70, C71, C
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https://en.wikipedia.org/wiki/NUTS%20statistical%20regions%20of%20Spain
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In the NUTS (Nomenclature of Territorial Units for Statistics) codes of Spain (ES), the following are the first-level political and administrative divisions.
Overall
NUTS Codes
Local administrative units
Below the NUTS levels, the two LAU (Local Administrative Units) levels are:
The LAU codes of Spain can be downloaded here:
NUTS codes
Older Codes
In the 2003 version, the two provinces of the Canary Islands were coded as follows:
See also
Subdivisions of Spain
ISO 3166-2 codes of Spain
FIPS region codes of Spain
Sources
Hierarchical list of the Nomenclature of territorial units for statistics - NUTS and the Statistical regions of Europe
Overview map of EU Countries - NUTS level 1
ESPANA - NUTS level 2
ESPANA - NUTS level 3
Correspondence between the NUTS levels and the national administrative units
List of current NUTS codes
Download current NUTS codes (ODS format)
Provinces of Spain, Statoids.com
Spain
Spain
Nuts
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https://en.wikipedia.org/wiki/Ahmet%20Y%C4%B1ld%C4%B1z
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Ahmet Yıldız (born 1979 in Sakarya, Turkey) is an American Turkish academic. He is currently a professor of physics and molecular cell biology at the University of California, Berkeley. He has contributed significantly to the understanding of transport within cells, in particular how motor proteins walk along filaments.
He received a B.S. in physics from Boğaziçi University, Istanbul, in 2001, followed by a Ph.D. from the University of Illinois at Urbana–Champaign in 2006. After postdoctoral work with Prof. Ron Vale at UCSF he joined the faculty of University of California, Berkeley in 2008.
In 2003 Yildiz received the Foresight Distinguished Student Award for his study of the motion of the molecular motor myosin V. According to the Foresight Institute: "The Distinguished Student Award recognizes the college graduate or undergraduate student whose work is deemed most notable in advancing the development and understanding of molecular nanotechnology." The award was presented during the Foresight Conference on Molecular Nanotechnology, October 10–12, 2003, in San Francisco. The Foresight Institute Distinguished Student Award was created in 1997, and is awarded annually.
Yildiz was awarded the 2005 GE & Science Prize for Young Life Scientists.
Yildiz currently teaches physics at University of California, Berkeley.
References
External links
Foresight Award notice
"Molecular motor Myosin VI moves ’hand over hand’, researchers say" by James E. Kloeppel (accessed 13 January
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https://en.wikipedia.org/wiki/Dom%C5%BEale%20radio%20transmitter
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The Domžale radio transmitter is a facility for medium wave broadcasting in Domžale, in Slovenia. The transmitter is fully transistorized. It could be received easily at a medium wave frequency of 918 kHz across the whole of Europe at night-time. It was the strongest radio transmitter of the Republic of Slovenia, broadcasting the first national radio channel.
History
The first transmitter was built in 1927 and started operation in September 1928 with the transmission from a fair in Ljubljana, and later a solemn broadcast of Franc Finžgar talking about Slovene language and Oton Župančič reading verses from his poem Duma. The transmitter had the power of 2.5 kilowatts, upgraded in 1932 to 5 kW and in 1939 to over 100 kW. A t-antenna with 5 wires, it was hung on two 120-metre tall steel framework masts, which were insulated against the ground. It was destroyed by German airplanes on 11 April 1941, during the invasion of Yugoslavia in World War II.
In 1949, the reconstruction of the transmitter started under the new socialist government. The transmitter was equipped with a 60-metre tall guyed tube mast, which was insulated against the ground. It entered service on 25 March 1951. This radio mast was replaced a little later by a 136-metre high guyed steel framework mast, which was also insulated against the ground.
In 1969, the transmitting power was increased to 200 kilowatts. In the course of the roll-out of the Geneva wave plan the transmitter got the licence to work with an
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https://en.wikipedia.org/wiki/Super%20vector%20space
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In mathematics, a super vector space is a -graded vector space, that is, a vector space over a field with a given decomposition of subspaces of grade and grade . The study of super vector spaces and their generalizations is sometimes called super linear algebra. These objects find their principal application in theoretical physics where they are used to describe the various algebraic aspects of supersymmetry.
Definitions
A super vector space is a -graded vector space with decomposition
Vectors that are elements of either or are said to be homogeneous. The parity of a nonzero homogeneous element, denoted by , is or according to whether it is in or ,
Vectors of parity are called even and those of parity are called odd. In theoretical physics, the even elements are sometimes called Bose elements or bosonic, and the odd elements Fermi elements or fermionic. Definitions for super vector spaces are often given only in terms of homogeneous elements and then extended to nonhomogeneous elements by linearity.
If is finite-dimensional and the dimensions of and are and respectively, then is said to have dimension . The standard super coordinate space, denoted , is the ordinary coordinate space where the even subspace is spanned by the first coordinate basis vectors and the odd space is spanned by the last .
A homogeneous subspace of a super vector space is a linear subspace that is spanned by homogeneous elements. Homogeneous subspaces are super vector spaces in t
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https://en.wikipedia.org/wiki/Nijmegen%20breakage%20syndrome
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Nijmegen breakage syndrome (NBS) is a rare autosomal recessive congenital disorder causing chromosomal instability, probably as a result of a defect in the double Holliday junction DNA repair mechanism and/or the synthesis dependent strand annealing mechanism for repairing double strand breaks in DNA (see Homologous recombination).
NBS1 codes for a protein (nibrin) that has two major functions: (1) to stop the cell cycle in the S phase, when there are errors in the cell DNA (2) to interact with FANCD2 that can activate the BRCA1/BRCA2 pathway of DNA repair. This explains why mutations in the NBS1 gene lead to higher levels of cancer (see Fanconi anemia, Cockayne syndrome.)
The name derives from the Dutch city Nijmegen, where the condition was first described.
Most people with NBS have West Slavic origins. The largest number of them live in Poland.
Presentation
It is characterized by microcephaly, a distinct facial appearance, short stature, immunodeficiency, radiation sensitivity and a strong predisposition to lymphoid malignancy. NBS is caused by a mutation in the NBS1 gene. Unsurprisingly, many of the features are similar to ataxia telangiectasia (AT) and this syndrome was sometimes termed AT-variant 1, as the protein mutated in AT, ATM, interacts with the MRE11/RAD50/NBS1 (MRN) complex. Other syndromes with clinical features similar to Nijmegen Breakage Syndrome include RAD50 deficiency and Cernunnos/NHEJ deficiency.
Cause
NBS is caused by a mutation in the NBS1
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https://en.wikipedia.org/wiki/CJKR-FM
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CJKR-FM is a Canadian radio station broadcasting on the assigned frequency of 97.5 MHz in Winnipeg, Manitoba. It airs an active rock format with the on-air brand name Power 97. The station is owned and operated by Corus Entertainment, which also owns sister stations CJOB and CFPG-FM. The studios and offices are located at 201 Portage Avenue in downtown Winnipeg, while its transmitter is located on Brady Road in south Winnipeg.
CJKR was formerly the most powerful FM radio station in Canada, operating with 310,000 watts. Most FM stations in Canada and the United States run 100,000 watts or less. Because CJKR-FM is one of the oldest FM stations in Canada, it was grandfathered with a much higher power. (In Winnipeg, CBW-FM also operates with an unusually high power, 160,000 watts). Following a fire to its transmitter in 2021, the station has been operating on reduced power, with plans to install a new HD Radio antenna operating at 93,900 watts. Power 97 is simulcast on Shaw Direct channel 860.
History
The station first signed on the air on May 27, 1948 as CJOB-FM, an FM simulcast of CJOB. The station applied to the Board of Broadcast Governors (BBG) to move its broadcast frequency from 103.1 MHz to the current 97.5 MHz. It began airing distinct programming in 1962, featured a country format as CHMM-FM in the late 1970s and early 1980s, and then changed its format to soft rock and its call sign to CKIS-FM in 1984. In the late 1980s, CKIS moved to a rock format, which was not in
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https://en.wikipedia.org/wiki/Blessed%20Is%20the%20Fruit
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Blessed Is the Fruit is a novel by Robert Antoni. Published in 1997 by Henry Holt, it explores the fluid boundaries of race in the Caribbean.
1997 novels
Trinidad and Tobago novels
Novels set in the Caribbean
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https://en.wikipedia.org/wiki/Viva%20Knievel%21
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Viva Knievel! is a 1977 American action film directed by Gordon Douglas and starring Evel Knievel (as himself), Gene Kelly and Lauren Hutton, with an ensemble supporting cast including Red Buttons, Leslie Nielsen, Cameron Mitchell, Frank Gifford, Dabney Coleman and Marjoe Gortner.
Plot
Daredevil motorcycle rider Evel Knievel stars as himself in this fictional story. The film opens with Knievel sneaking into an orphanage late at night to deliver presents: Evel Knievel action figures. One of the boys casts away his crutches, telling Knievel that he'll walk after his accident just as Knievel had.
Knievel then prepares for another of his stunt jumps. We are introduced to his alcoholic mechanic Will Atkins (Gene Kelly), who was a former stunt rider himself before his wife died, driving him to drink. While signing autographs, Knievel is ambushed by photojournalist Kate Morgan (Lauren Hutton), who has been sent to photograph the jump: if Knievel is killed, it will be a great story.
As it happens, Evel does crash while attempting the stunt, and though badly injured, survives. He berates Morgan, announces his retirement, and is taken to the hospital.
While rehabilitating, Knievel resists all attempts to get back on the horse, including those from Jessie (Marjoe Gortner), a former protégé with mysterious backers who want Evel to do a jump in Mexico. Eventually, though, Knievel relents and agrees.
A subplot develops when Will's estranged son Tommy shows up from boarding school, a
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https://en.wikipedia.org/wiki/Bradie%20James
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Bradie Gene James (born January 17, 1981) is a former American football linebacker in the National Football League (NFL) for the Dallas Cowboys and the Houston Texans. He played college football at Louisiana State University.
Early years
James went to Wossman High School in Monroe, Louisiana from 1995 to 1997. In 1998, he transferred to West Monroe High School in West Monroe, Louisiana, where he played under legendary coach Don Shows.
During his senior year, James posted 136 tackles (10 for loss), five sacks and three fumble recoveries, while helping his team win the 1998 Class 5A state title. He also earned Parade All-American, All-State, Football Magazine’s All-Louisiana Team, class 5A defensive MVP and district defensive MVP honors.
College career
In 1999, James accepted a scholarship from Louisiana State University (LSU) to play college football for LSU's football team. He became the second player in LSU history to register more than 400 career tackles (behind Al Richardson), finishing with 418 tackles, including 33 for a loss, 29 quarterback pressures, 14 sacks, eight pass deflections, four forced fumbles, two fumble recoveries and two interceptions.
As a freshman (1999), he was named the starter at weakside linebacker, posting 41 tackles, three sacks, and one interception. The following year, he recorded 110 tackles (second on the team), five sacks (led the team) and was named the Defensive MVP of the 2000 Peach Bowl.
During his junior year, LSU's defense was dubb
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https://en.wikipedia.org/wiki/Schoof%E2%80%93Elkies%E2%80%93Atkin%20algorithm
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The Schoof–Elkies–Atkin algorithm (SEA) is an algorithm used for finding the order of or calculating the number of points on an elliptic curve over a finite field. Its primary application is in elliptic curve cryptography. The algorithm is an extension of Schoof's algorithm by Noam Elkies and A. O. L. Atkin to significantly improve its efficiency (under heuristic assumptions).
Details
The Elkies-Atkin extension to Schoof's algorithm works by restricting the set of primes considered to primes of a certain kind. These came to be called Elkies primes and Atkin primes respectively. A prime is called an Elkies prime if the characteristic equation: splits over , while an Atkin prime is a prime that is not an Elkies prime. Atkin showed how to combine information obtained from the Atkin primes with the information obtained from Elkies primes to produce an efficient algorithm, which came to be known as the Schoof–Elkies–Atkin algorithm. The first problem to address is to determine whether a given prime is Elkies or Atkin. In order to do so, we make use of modular polynomials that parametrize pairs of -isogenous elliptic curves in terms of their j-invariants (in practice alternative modular polynomials may also be used but for the same purpose).
If the instantiated polynomial has a root in then is an Elkies prime, and we may compute a polynomial whose roots correspond to points in the kernel of the -isogeny from to . The polynomial is a divisor of the corresponding divisi
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https://en.wikipedia.org/wiki/Back%20pressure
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Back pressure (or backpressure) is the term for a resistance to the desired flow of fluid through pipes. Obstructions or tight bends create backpressure via friction loss and pressure drop.
Explanation
A common example of backpressure is that caused by the exhaust system (consisting of the exhaust manifold, catalytic converter, muffler and connecting pipes) of an automotive four-stroke engine, which has a negative effect on engine efficiency, resulting in a decrease of power output that must be compensated by increasing fuel consumption.
In a piston-ported two-stroke engine, however, the situation is more complicated, due to the need to prevent unburned fuel/air mixture from passing right through the cylinders into the exhaust. During the exhaust phase of the cycle, backpressure is even more undesirable than in a four-stroke engine, as there is less time available for exhaust and the lack of pumping action from the piston to force the exhaust out of the cylinder. However, since the exhaust port necessarily remains open for a time after scavenging is completed, unburned mixture can follow the exhaust out of the cylinder, wasting fuel and increasing pollution. This can only be prevented if the pressure at the exhaust port is greater than that in the cylinder. Since the timing of this process is determined mainly by exhaust system geometry, which is extremely difficult to make variable, correct timing and therefore optimum engine efficiency can typically only be achieved ove
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https://en.wikipedia.org/wiki/Yang%E2%80%93Baxter%20equation
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In physics, the Yang–Baxter equation (or star–triangle relation) is a consistency equation which was first introduced in the field of statistical mechanics. It depends on the idea that in some scattering situations, particles may preserve their momentum while changing their quantum internal states. It states that a matrix , acting on two out of three objects, satisfies
In one-dimensional quantum systems, is the scattering matrix and if it satisfies the Yang–Baxter equation then the system is integrable. The Yang–Baxter equation also shows up when discussing knot theory and the braid groups where corresponds to swapping two strands. Since one can swap three strands two different ways, the Yang–Baxter equation enforces that both paths are the same.
It takes its name from independent work of C. N. Yang from 1968, and R. J. Baxter from 1971.
General form of the parameter-dependent Yang–Baxter equation
Let be a unital associative algebra. In its most general form, the parameter-dependent Yang–Baxter equation is an equation for , a parameter-dependent element of the tensor product (here, and are the parameters, which usually range over the real numbers ℝ in the case of an additive parameter, or over positive real numbers ℝ+ in the case of a multiplicative parameter).
Let for , with algebra homomorphisms determined by
The general form of the Yang–Baxter equation is
for all values of , and .
Parameter-independent form
Let be a unital associative algebra. The pa
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https://en.wikipedia.org/wiki/Sadie%20McKee
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Sadie McKee is a 1934 American pre-Code, romantic-drama film directed by Clarence Brown, starring Joan Crawford, and featuring Gene Raymond, Franchot Tone, Edward Arnold, and Esther Ralston. The film is based on the 1933 short story "Pretty Sadie McKee", by Viña Delmar. Crawford plays the title character, from young working girl through poverty, a marriage into enormous wealth and finally a (seemingly) settled life on her own terms.
Sadie McKee is the third of seven films Crawford and Franchot Tone made together. At the time of filming, Crawford recently had divorced Douglas Fairbanks Jr., and soon she and Tone were involved romantically. The couple married in 1935.
The song “All I Do Is Dream of You” features in the film’s opening titles and certain key sequences, sung (for the most part) by Gene Raymond. It was written by Nacio Herb Brown (music) and Arthur Freed (lyrics) for Sadie McKee. Since 1952, audiences have known this song best from its use in the film Singin' in the Rain, where it is sung at high speed by Debbie Reynolds and a group of chorus girls after Reynolds pops out of a cake at a Hollywood party. It also was used in A Night at the Opera (1935) and Crimes and Misdemeanors (1989).
Plot
Sadie McKee (Crawford) works part-time as a serving maid in the same household where her mother is a cook, and is admired by lawyer Michael Alderson (Tone), the son of her employer. However, when Michael talks badly of Tommy Wallace (Gene Raymond), her boyfriend, during a fam
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https://en.wikipedia.org/wiki/Electrodialysis
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Electrodialysis (ED) is used to transport salt ions from one solution through ion-exchange membranes to another solution under the influence of an applied electric potential difference. This is done in a configuration called an electrodialysis cell. The cell consists of a feed (dilute) compartment and a concentrate (brine) compartment formed by an anion exchange membrane and a cation exchange membrane placed between two electrodes. In almost all practical electrodialysis processes, multiple electrodialysis cells are arranged into a configuration called an electrodialysis stack, with alternating anion and cation-exchange membranes forming the multiple electrodialysis cells. Electrodialysis processes are different from distillation techniques and other membrane based processes (such as reverse osmosis (RO)) in that dissolved species are moved away from the feed stream, whereas other processes move away the water from the remaining substances. Because the quantity of dissolved species in the feed stream is far less than that of the fluid, electrodialysis offers the practical advantage of much higher feed recovery in many applications.
Method
In an electrodialysis stack, the dilute (D) feed stream, brine or concentrate (C) stream, and electrode (E) stream are allowed to flow through the appropriate cell compartments formed by the ion-exchange membranes. Under the influence of an electrical potential difference, the negatively charged ions (e.g., chloride) in the dilute stream m
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https://en.wikipedia.org/wiki/Rotational%E2%80%93vibrational%20coupling
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In physics, rotational–vibrational coupling occurs when the rotation frequency of a system is close to or identical to a natural internal vibration frequency. The animation on the right shows ideal motion, with the force exerted by the spring and the distance from the center of rotation increasing together linearly with no friction.
In rotational-vibrational coupling, angular velocity oscillates. By pulling the circling masses closer together, the spring transfers its stored strain energy into the kinetic energy of the circling masses, increasing their angular velocity. The spring cannot bring the circling masses together, since the spring's pull weakens as the circling masses approach. At some point, the increasing angular velocity of the circling masses overcomes the pull of the spring, causing the circling masses to increasingly distance themselves. This increasingly strains the spring, strengthening its pull and causing the circling masses to transfer their kinetic energy into the spring's strain energy, thereby decreasing the circling masses' angular velocity. At some point, the pull of the spring overcomes the angular velocity of the circling masses, restarting the cycle.
In helicopter design, helicopters must incorporate damping devices, because at specific angular velocities, the rotorblade vibrations can reinforced themselves by rotational-vibrational coupling, and build up catastrophically. Without damping, these vibrations would cause the rotorblades to break loo
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https://en.wikipedia.org/wiki/Tobit%20model
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In statistics, a tobit model is any of a class of regression models in which the observed range of the dependent variable is censored in some way. The term was coined by Arthur Goldberger in reference to James Tobin, who developed the model in 1958 to mitigate the problem of zero-inflated data for observations of household expenditure on durable goods. Because Tobin's method can be easily extended to handle truncated and other non-randomly selected samples, some authors adopt a broader definition of the tobit model that includes these cases.
Tobin's idea was to modify the likelihood function so that it reflects the unequal sampling probability for each observation depending on whether the latent dependent variable fell above or below the determined threshold. For a sample that, as in Tobin's original case, was censored from below at zero, the sampling probability for each non-limit observation is simply the height of the appropriate density function. For any limit observation, it is the cumulative distribution, i.e. the integral below zero of the appropriate density function. The tobit likelihood function is thus a mixture of densities and cumulative distribution functions.
The likelihood function
Below are the likelihood and log likelihood functions for a type I tobit. This is a tobit that is censored from below at when the latent variable . In writing out the likelihood function, we first define an indicator function :
Next, let be the standard normal cumulative dis
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https://en.wikipedia.org/wiki/George%20Ndah
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George Ebialimolisa Ndah (born 23 December 1974) is an English-born Nigerian former professional footballer who played as a striker from 1992 until 2006.
He played in the Premier League for Crystal Palace and in the Football League for AFC Bournemouth, Gillingham, Swindon Town and Wolverhampton Wanderers. In 1999, he was called up to play international football by Nigeria, but injury prevented him from making his debut and he was never selected again.
Club career
Crystal Palace
Born in Camberwell, England, Ndah began his career as an apprentice at Crystal Palace, turning professional there in August 1992. Prior to that he had played youth-team football at Dulwich Hamlet. His older brother Jamie was also a footballer.
During his time at Selhurst Park he was loaned out twice. The first time was in 1995, when he played 15 games for AFC Bournemouth, then, two years later, he had a short spell at Gillingham, one that was curtailed by illness.
Swindon Town
Ndah moved to Swindon Town for £500,000, in November 1997, and in his two years with the Wiltshire side, he was a firm favourite of the crowd there. He scored 12 minutes into his debut against Middlesbrough on 22 November 1997.
Wolverhampton Wanderers
He departed for Wolverhampton Wanderers in October 1999, brought about by financial problems at the County Ground. He signed for Wolves at a cost of £1 million. Unfortunately his Wolves career suffered an early blow when his leg was broken by Matt Carbon during only his third
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https://en.wikipedia.org/wiki/The%20%27In%27%20Crowd
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"The 'In' Crowd" is a 1964 song written by Billy Page and arranged by his brother Gene and originally performed by Dobie Gray on his album Dobie Gray Sings for "In" Crowders That Go "Go-Go". It appeared on an episode of Dick Clark's Rock, Roll & Remember, featuring in the last week of November 1964, the month Gray's rendition was released.
Chart performance
In the US, Gray's powerful Motown-like version, complete with brass section, reached number 11 on the Hot Rhythm & Blues Singles chart and number 13 on the Billboard Hot 100 on 20 February 1965. Outside the US, "The 'In' Crowd" went to number 25 on the UK Singles Chart, and number 8 in Canada. Gray's Shindig! performance of the song aired on 10 March 1965.
Ramsey Lewis's instrumental version
The Ramsey Lewis Trio recorded an instrumental version of the tune later in 1965. Their jazzy take, recorded live at Bohemian Caverns, a Washington, D.C., night club, was released in June 1965 and reached number 5 on the Hot 100 on 9 October 1965, as well as peaking at number 2 for three weeks on the Hot Rhythm & Blues Singles chart. In Canada, the record reached number 6 in the RPM charts. An album of the live recording used the song's name.
In 2009, this version of the song recorded in 1965 on Argo Records was inducted into the Grammy Hall of Fame.
Other versions
Bryan Ferry on his 1974 album Another Time, Another Place; also released as a single, reaching number 13 on the UK Singles Chart.
References
External links
1965
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https://en.wikipedia.org/wiki/-ase
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The suffix -ase is used in biochemistry to form names of enzymes. The most common way to name enzymes is to add this suffix onto the end of the substrate, e.g. an enzyme that breaks down peroxides may be called peroxidase; the enzyme that produces telomeres is called telomerase. Sometimes enzymes are named for the function they perform, rather than substrate, e.g. the enzyme that polymerizes (assembles) DNA into strands is called polymerase; see also reverse transcriptase.
Etymology
The -ase suffix is a libfix derived from "diastase", the first recognized enzyme. Its usage in subsequently discovered enzymes was proposed by Émile Duclaux, with the intention of honoring the first scientists to isolate diastase.
See also
Amylase
DNA polymerase
References
ase
Biological nomenclature
ase
ase
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https://en.wikipedia.org/wiki/European%20Society%20of%20Gene%20and%20Cell%20Therapy
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European Society of Gene & Cell Therapy (ESGCT) formerly European Society of Gene Therapy (ESGT) is a legally registered professional body which emerged from a small working group in 1992 that focused on human gene therapy.
The objectives of the ESGT include the following:
promote basic and clinical research in gene therapy;
facilitate education (and the exchange of information and technologies) related to gene transfer and therapy;
serve as a professional adviser to the gene therapy community and various regulatory bodies in Europe.
The official journal of the ESGT is The Journal of Gene Medicine.
Collaborations
The ESGT works with other entities in the scientific communities in the event that an adverse effect to a specific gene therapy is discovered. Investigations the ESGT has been involved with include the adverse effects discovered during the French X-SCID gene therapy trial. The ESGT hosted a forum of 500 researchers from various facilities around the world, including representatives from the Stanford University and the Sloan Kettering Cancer Research Center.
External links
Official Site
Researchers from Israel, Southern California to Present Stem Cell Symposium
Researchers team up to tackle cystic fibrosis
Genetics societies
European medical and health organizations
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https://en.wikipedia.org/wiki/American%20Society%20of%20Gene%20and%20Cell%20Therapy
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American Society of Gene & Cell Therapy (ASGCT) is a professional non-profit medical and scientific organization based in Milwaukee, dedicated to understanding, development and application of gene, related cell and nucleic acid therapies, as well as promotion of professional and public education on gene therapy. With more than 4,800 members in the United States and worldwide, today ASGCT is the largest association of individuals involved in gene and cell therapy research.
Molecular Therapy is the official journal of the ASGCT.
References
External links
American Society of Gene & Cell Therapy Official site
Medical and health organizations based in Wisconsin
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https://en.wikipedia.org/wiki/College%20Football%20News
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College Football News (CFN) is a magazine and website published by College Football News, Inc., headquartered in Chicago, Illinois. News coverage includes scores, statistics, rankings, and reports on college football games. Analysis includes comparisons between teams, predictions of game outcomes and high-school recruiting information. They also give awards to players in various categories.
The website has fan discussion boards on topics relating to college football. Content from College Football News is used on partner sites, such as that of Fox Sports, and by independent organizations, such as the National Football League.
In the summer of 2006, the College Football News website joined the Scout.com Network. However, they maintain separate editorial selections of All-America teams.
References
Mack Brown Texas Football The University of Texas official football webpage
Orangemen recognized by CollegeFootballNews.com Syracuse University Athletics
Bowl Matchups Fox Sports
NFL Draft Analysis National Football League
Scout.com Scout.com
External links
College Football News
American football websites
Companies based in Chicago
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https://en.wikipedia.org/wiki/Variable%20%28mathematics%29
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In mathematics, a variable (from Latin variabilis, "changeable") is a symbol that represents a mathematical object. A variable may represent a number, a vector, a matrix, a function, the argument of a function, a set, or an element of a set.
Algebraic computations with variables as if they were explicit numbers solve a range of problems in a single computation. For example, the quadratic formula solves any quadratic equation by substituting the numeric values of the coefficients of that equation for the variables that represent them in the quadratic formula. In mathematical logic, a variable is either a symbol representing an unspecified term of the theory (a meta-variable), or a basic object of the theory that is manipulated without referring to its possible intuitive interpretation.
History
In ancient works such as Euclid's Elements, single letters refer to geometric points and shapes. In the 7th century, Brahmagupta used different colours to represent the unknowns in algebraic equations in the Brāhmasphuṭasiddhānta. One section of this book is called "Equations of Several Colours".
At the end of the 16th century, François Viète introduced the idea of representing known and unknown numbers by letters, nowadays called variables, and the idea of computing with them as if they were numbers—in order to obtain the result by a simple replacement. Viète's convention was to use consonants for known values, and vowels for unknowns.
In 1637, René Descartes "invented the conventi
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https://en.wikipedia.org/wiki/Gene%20Stanlee
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Eugene Stanley Zygowicz (January 1, 1917 – September 23, 2005) was an American professional wrestler, better known by his ring name "Mr. America" Gene Stanlee.
Early life
Zygowicz was born in Chicago, Illinois. His parents, Victoria and Paul Zygowicz, were Polish immigrants. Zygowicz was the eighth child of fifteen—he had eight brothers and six sisters.
When he was five, Zygowicz fell down a set of stairs, and was partially paralyzed. He was given his last rites; however, he regained his health after being partially inspired by seeing a strongman at a church. He began wrestling and competing against other boys when he was eight and collected iron from a railyard to fashion his own homemade gym to develop his physique. By his own count, he claimed to have 165 bodybuilding trophies and 50 gold medals from bodybuilding competitions.
During World War II, Zygowicz, along with his brother Steve, served on a U.S. Navy floating repair ship as a machinist. He reportedly wrestled 134 matches for the entertainment of other servicemen in the South Pacific area during the war. He was termed "pinup boy of the Navy", and once he received his discharge from the Navy, he was sought out by wrestling promoters, who wanted to capitalize on his publicity.
Professional wrestling career
Zygowicz's first professional match was April 26, 1946 in Milwaukee against Leo Kirilenko under the ring name "Gene Stanlee". All his early matches took place in the Chicago–Milwaukee area.
His career as Gene "
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https://en.wikipedia.org/wiki/Stonehenge%20replicas%20and%20derivatives
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This is a list of Stonehenge replicas and derivatives that seeks to collect all the non-ephemeral examples together. The fame of the prehistoric monument of Stonehenge in England has led to many efforts to recreate it, using a variety of different materials, around the world. Some have been carefully built as astronomically aligned models whilst others have been examples of artistic expression or tourist attractions.
Astronomically aligned replicas
Australia and New Zealand
The only astronomically aligned, full-scale, "exact" replica of (a pristine) Stonehenge in natural stone (granite) is Esperance Stonehenge at Esperance, Western Australia. It cost over A$250,000 to build. Some of the blocks weigh more than 50 tonnes.
Stonehenge Aotearoa, in the Wairarapa region of New Zealand, is a modern adaptation aligned with the astronomy seen from the Antipodes. It was built by the Phoenix Astronomical Society from wood and sprayed concrete.
A full-scale replica in sandstone was started in the rural township of Buckland in Tasmania in the first years of the 21st century, but was demolished by order of the municipal authorities. It did not have the necessary planning approval from the local council.
North America
The Maryhill Stonehenge: A full-size concrete replica of Stonehenge, as it would have been originally built, saw construction commence and had its original dedication on 4 July 1918. Built in Maryhill, Washington by Sam Hill, it was the first monument in the United Stat
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https://en.wikipedia.org/wiki/Cell%20cycle%20checkpoint
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Cell cycle checkpoints are control mechanisms in the eukaryotic cell cycle which ensure its proper progression. Each checkpoint serves as a potential termination point along the cell cycle, during which the conditions of the cell are assessed, with progression through the various phases of the cell cycle occurring only when favorable conditions are met. There are many checkpoints in the cell cycle, but the three major ones are: the G1 checkpoint, also known as the Start or restriction checkpoint or Major Checkpoint; the G2/M checkpoint; and the metaphase-to-anaphase transition, also known as the spindle checkpoint. Progression through these checkpoints is largely determined by the activation of cyclin-dependent kinases by regulatory protein subunits called cyclins, different forms of which are produced at each stage of the cell cycle to control the specific events that occur therein.
Background
All living organisms are the products of repeated rounds of cell growth and division. During this process, known as the cell cycle, a cell duplicates its contents and then divides in two. The purpose of the cell cycle is to accurately duplicate each organism's DNA and then divide the cell and its contents evenly between the two resulting cells. In eukaryotes, the cell cycle consists of four main stages: G1, during which a cell is metabolically active and continuously grows; S phase, during which DNA replication takes place; G2, during which cell growth continues and the cell synthesiz
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https://en.wikipedia.org/wiki/Exonuclease%20III
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Exonuclease III (ExoIII) is an enzyme that belongs to the exonuclease family. ExoIII catalyzes the stepwise removal of mononucleotides from 3´-hydroxyl termini of double-stranded DNA. A limited number of nucleotides are removed during each binding event, resulting in coordinated progressive deletions within the population of DNA molecules.
Function
The preferred substrates are blunt or recessed 3´-termini, although ExoIII also acts at nicks in duplex DNA to produce single-strand gaps. The enzyme is not active on single-stranded DNA, and thus 3´-protruding termini are resistant to cleavage. The degree of resistance depends on the length of the extension, with extensions 4 bases or longer being essentially resistant to cleavage. This property is used to produce unidirectional deletions from a linear molecule with one resistant (3´-overhang) and one susceptible (blunt or 5´-overhang) terminus.
ExoIII activity depends partially on the DNA helical structure and displays sequence dependence (C>A=T>G).
ExoIII has also been reported to have RNase H, 3´-phosphatase and AP-endonuclease activities.
Current Studies
There are many different exonucleases and many are still to be discovered in bacteria, current studies are being conducted in E. coli. Many exonucleases fall into superfamilies with different domains of life proving that exonuclease III has shown to be ancient. Exonucleases evolved early in the history of life and have vital biological roles.
Regulation
Temperature, salt
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https://en.wikipedia.org/wiki/Sot
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Sot or SOT may refer to:
Mathematics, science, and technology
Small-outline transistor
Society of Toxicology, U.S.
Sound on tape, in television broadcasting
Strong operator topology, in mathematics
Places
Sot (village), Vojvodina, Serbia
Sodankylä Airfield, Sodankylä, Lapland, Finland, IATA code
Stoke-on-Trent railway station, England, station code
Other uses
Sotho language, a Bantu language of South Africa, ISO 639 code
Special Occupational Taxpayers, some US Firearm Licensees
Gamasot or sot, a Korean cauldron
Gazeta Sot, a daily newspaper in Albania
See also
Sots (disambiguation)
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https://en.wikipedia.org/wiki/VRR%20%28disambiguation%29
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Verkehrsverbund Rhein-Ruhr is a public transport association in Germany.
VRR may also refer to:
VRR (program), a vector graphics editor
Variable refresh rate, displays that support a dynamic refresh rate
Vehicular Reactive Routing protocol
Voters Registration Record, a process of voter registration in the Philippines
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https://en.wikipedia.org/wiki/Mdm2
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Mouse double minute 2 homolog (MDM2) also known as E3 ubiquitin-protein ligase Mdm2 is a protein that in humans is encoded by the MDM2 gene. Mdm2 is an important negative regulator of the p53 tumor suppressor. Mdm2 protein functions both as an E3 ubiquitin ligase that recognizes the N-terminal trans-activation domain (TAD) of the p53 tumor suppressor and as an inhibitor of p53 transcriptional activation.
Discovery and expression in tumor cells
The murine double minute (mdm2) oncogene, which codes for the Mdm2 protein, was originally cloned, along with two other genes (mdm1 and mdm3) from the transformed mouse cell line 3T3-DM. Mdm2 overexpression, in cooperation with oncogenic Ras, promotes transformation of primary rodent fibroblasts, and mdm2 expression led to tumor formation in nude mice. The human homologue of this protein was later identified and is sometimes called Hdm2. Further supporting the role of mdm2 as an oncogene, several human tumor types have been shown to have increased levels of Mdm2, including soft tissue sarcomas and osteosarcomas as well as breast tumors. The MDM2 oncoprotein ubiquitinates and antagonizes p53 but may also carry out p53-independent functions. MDM2 supports the Polycomb-mediated repression of lineage-specific genes, independent of p53. MDM2 depletion in the absence of p53 promoted the differentiation of human mesenchymal stem cells and diminished clonogenic survival of cancer cells. Most of the MDM2-controlled genes also responded to th
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https://en.wikipedia.org/wiki/Quantum%20mirage
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In physics, a quantum mirage is a peculiar result in quantum chaos. Every system of quantum dynamical billiards will exhibit an effect called scarring, where the quantum probability density shows traces of the paths a classical billiard ball would take. For an elliptical arena, the scarring is particularly pronounced at the foci, as this is the region where many classical trajectories converge. The scars at the foci are colloquially referred to as the "quantum mirage".
The quantum mirage was first experimentally observed by Hari Manoharan, Christopher Lutz and Donald Eigler at the IBM Almaden Research Center in San Jose, California in 2000. The effect is quite remarkable but in general agreement with prior work on the quantum mechanics of dynamical billiards in elliptical arenas.
Quantum corral
The mirage occurs at the foci of a quantum corral, a ring of atoms arranged in an arbitrary shape on a substrate. The quantum corral was demonstrated in 1993 by Lutz, Eigler, and Crommie using an elliptical ring of iron atoms on a copper surface using the tip of a low-temperature scanning tunneling microscope to manipulate individual atoms. The ferromagnetic iron atoms reflected the surface electrons of the copper inside the ring into a wave pattern, as predicted by the theory of quantum mechanics.
Quantum corrals can be viewed as artificial atoms that even show similar chemical bonding properties as real atoms.
The size and shape of the corral determine its quantum states, inc
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https://en.wikipedia.org/wiki/Strength%20in%20Numbers%20%2824-7%20Spyz%20album%29
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Strength in Numbers is an album by 24-7 Spyz. It is the only album to feature Jeff Brodnax, who replaced original vocalist P. Fluid in 1991. On their third effort, the Spyz concentrate on simpler and more direct songwriting. The album has been described as a hard rock album with elements of heavy metal, funk, New York hardcore, R&B, jazz and reggae.
The Seattle grunge movement overpowered the music industry in 1992, leaving the Spyz without a record contract or media attention in the midst of their creative peak.
After the release of the album, the Spyz would take a break before reforming their classic lineup in 1995.
Like many 24-7 Spyz albums, this recording is out of print but this album is available on streaming platforms.
Track listing
"Break the Chains"
"Crime Story"
"Judgment Day"
"Understanding"
"Got It Goin' On"
"My Desire"
"Purple"
"Stuntman"
"Earth and Sky"
"Room #9"
"Sireality"
"Last Call"
"I'm Not Going"
"Traveling Day"
Personnel
Jeff Brodnax – vocals
Jimi Hazel – guitar
Rick Skatore – bass
Joel Maitoza – drums
References
1992 albums
24-7 Spyz albums
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https://en.wikipedia.org/wiki/Xenin
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Xenin is a peptide hormone secreted from the chromogranin A-positive enteroendocrine cells called the K-cells in the mucous membrane of the duodenum and stomach of the upper gut. The peptide has been found in humans, dogs, pigs, rats, and rabbits.
In humans, xenin circulates in the blood plasma. There is a relationship between peaks of xenin concentration in the plasma and the third phase of the Migrating Motor Complex. For example, infusion of synthetic xenin in fasting volunteers will cause phase III activity. After a meal (the 'postprandial state'), infusion of xenin increases both frequency and the percentage of aborally propagated contractions. In higher concentrations xenin stimulates exocrine pancreatic secretion and inhibits the gastrin-stimulated secretion of acid in dogs. Xenin is also produced in neuroendocrine tumors of the duodenal mucosa.
In vitro, xenin interacts with the neurotensin receptor 1.
Structure and sequence
Xenin is a 25-amino acid polypeptide. The amino acid sequence of xenin is identical to the N-terminal end of cytoplasmic coatomer subunit alpha, from which xenin can be cleaved by aspartic proteases. Xenin is structurally related to the amphibian peptide xenopsin and to the neuropeptide neurotensin.
Surpassed by insulin, xenin reflects the second highest degree of homology traced along the evolutionary tree among the regulatory peptides, indicating its prominent structural conservatism.
Proxenin
Proxenin is the precursor to xenin. It is a
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https://en.wikipedia.org/wiki/97.1%20FM
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The following radio stations broadcast on FM frequency 97.1 MHz:
Brasil
Radio família Rio de Janeiro
Argentina
Alfa in Zárate, Buenos Aires
LRM743 FM Funes in Funes, Santa Fe
Radio María in Canals, Córdoba
Australia
Radio National in Port Macquarie, New South Wales
Radio National in Young, New South Wales
Radio National in Jindabyne, New South Wales
Rebel FM in Stanthorpe, Queensland
Triple J in Cairns, Queensland
Triple J in Emerald, Queensland
3MDR in Melbourne, Victoria
3GLR in Orbost, Victoria
Radio National in Kalgoorlie, Western Australia
Canada
CBHL-FM in Liverpool, Nova Scotia
CBL-FM-4 in Owen Sound, Ontario
CBON-FM-25 in Timmins, Ontario
CBTB-FM in Baie Verte, Newfoundland and Labrador
CFIL-FM in Gillam, Manitoba
CHLC-FM in Baie-Comeau, Quebec
CHLX-FM in Gatineau, Quebec
CIBM-FM-4 in Saint-Juste-du-Lac, Quebec
CIGL-FM in Belleville, Ontario
CITB-FM in Thunder Bay, Ontario
CJBP-FM in Neepawa, Manitoba
CJMG-FM in Penticton, British Columbia
CKDR-FM in Sioux Lookout and Red Lake, Ontario
CKFI-FM in Swift Current, Saskatchewan
CKRO-FM in Inkerman, New Brunswick
VF2064 in Fort St. James, British Columbia
VF2066 in Dease Lake, British Columbia
VF2121 in Lampman, Saskatchewan
VF2135 in Kitseguecla, British Columbia
VF2171 in Skidegate, British Columbia
VF2173 in Alexandria Reserve, British Columbia
VF2232 in New Bella Bella, British Columbia
VF2236 in Decker Lake Indian Reserve, British Columbia
VF2328 in Revelstoke, British Columbia
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https://en.wikipedia.org/wiki/Anerley
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Anerley () is an area of south east London, England, within the London Borough of Bromley. It is located south south-east of Charing Cross, to the south of Crystal Palace and Upper Norwood, west of Penge, north of Elmers End and South Norwood.
History
Origin and development
Anerley has never existed as an independent entity, but rather as a general area. Prior to the enclosure in 1827 and the relocation of the Crystal Palace to Penge Place at the top of Sydenham Hill, Anerley was an unoccupied part of Penge Common, and did not develop until the 19th century. The government Act of 1827 stipulated that a 50 feet (15 metres) wide, new road, was to be set out from Elmers End Road to what is now Church Road, Upper Norwood. In 1827, a Scottish silk manufacturer named William Sanderson bought land on the former Penge Common and built the first house in the area, which he named "Anerly Lodge", a Scottish and Northern English dialect word meaning "solitary" or "only", and the road subsequently became known as Anerley Road, also giving the name to the surrounding area. Sanderson's name is the first to appear in the first rate book, dated 18 June 1827, now held in the Anerley Town Hall.
Canal and railway
The Croydon Canal was opened on 22 October 1809, and passed through Anerley. The canal was a financial failure and lasted only 27 years, being sold to the London and Croydon Railway Company for £40,250. London and Croydon Railway would use much of the former canal for the new rail
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https://en.wikipedia.org/wiki/NGC%203486
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NGC 3486 is an intermediate barred spiral galaxy located about 27.4 million light years away in the constellation of Leo Minor. It has a morphological classification of SAB(r)c, which indicates it is a weakly barred spiral with an inner ring and loosely wound arms. This is a borderline, low-luminosity Seyfert galaxy with an active nucleus. However, no radio or X-ray emission has been detected from the core, and it may only have a small supermassive black hole with less than a million times the mass of the Sun.
References
External links
Leo Minor
3486
Intermediate spiral galaxies
17850411
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https://en.wikipedia.org/wiki/NGC%203521
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NGC 3521 is a flocculent intermediate spiral galaxy located around 26 million light-years away from Earth in the constellation Leo. It has a morphological classification of SAB(rs)bc, which indicates that it is a spiral galaxy with a trace of a bar structure (SAB), a weak inner ring (rs), and moderate to loosely wound arm structure (bc). The bar structure is difficult to discern, both because it has a low ellipticity and the galaxy is at a high inclination of 72.7° to the line of sight. The relatively bright bulge is nearly 3/4 the size of the bar, which may indicate the former is quite massive. The nucleus of this galaxy is classified as an HII LINER, as there is an H II region at the core and the nucleus forms a low-ionization nuclear emission-line region.
References
External links
'Fluffy' Spiral Galaxy Shines in New Photo
Intermediate spiral galaxies
Flocculent spiral galaxies
Leo (constellation)
3521
Astronomical objects discovered in 1784
033550
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https://en.wikipedia.org/wiki/Jacques-Louis%20Lions
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Jacques-Louis Lions (; 2 May 1928 – 17 May 2001) was a French mathematician who made contributions to the theory of partial differential equations and to stochastic control, among other areas. He received the SIAM's John von Neumann Lecture prize in 1986 and numerous other distinctions. Lions is listed as an ISI highly cited researcher.
Biography
After being part of the French Résistance in 1943 and 1944, Jacques-Louis Lions entered the École Normale Supérieure in 1947.
He was a professor of mathematics at the University of Nancy, the Faculty of Sciences of Paris, and the École Polytechnique.
In 1966 he sent an invitation to Gury Marchuk, the soviet mathematician to visit Paris. This was hand delivered by Général De Gaulle during his visit to Akademgorodok in June of that year.
He joined the prestigious Collège de France as well as the French Academy of Sciences in 1973.
In 1979, he was appointed director of the Institut National de la Recherche en Informatique et Automatique (INRIA), where he taught and promoted the use of numerical simulations using finite elements integration. Throughout his career, Lions insisted on the use of mathematics in industry, with a particular involvement in the French space program, as well as in domains such as energy and the environment.
This eventually led him to be appointed director of the Centre National d'Etudes Spatiales (CNES) from 1984 to 1992.
Lions was elected President of the International Mathematical Union in 1991 and also re
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https://en.wikipedia.org/wiki/%CE%91-Galactosidase
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α-Galactosidase ( EC 3.2.1.22, α-GAL, α-GAL A; systematic name α-D-galactoside galactohydrolase) is a glycoside hydrolase enzyme that catalyses the following reaction:
Hydrolysis of terminal, non-reducing α-D-galactose residues in α-D-galactosides, including galactose oligosaccharides, galactomannans and galactolipids
It catalyzes many catabolic processes, including cleavage of glycoproteins, glycolipids, and polysaccharides.
The enzyme is encoded by the GLA gene. Two recombinant forms of human α-galactosidase are called agalsidase α (INN) and agalsidase β (INN). A mold-derived form is the primary ingredient in gas relief supplements.
Function
This enzyme is a homodimeric glycoprotein that hydrolyses the terminal α-galactosyl moieties from glycolipids and glycoproteins. It predominantly hydrolyzes ceramide trihexoside, and it can catalyze the hydrolysis of melibiose into galactose and glucose.
Reaction mechanism
Disease relevance
Fabry disease
Signs and Symptoms
Defects in human α-GAL result in Fabry disease, a rare lysosomal storage disorder and sphingolipidosis that results from a failure to catabolize α-D-galactosyl glycolipid moieties. Characteristic features include episodes of pain in hands and feet (acroparesthesia), dark red spots on skin (angiokeratoma), decreased sweating (hypohidrosis), decreased vision (corneal opacity), gastrointestinal problems, hearing loss, tinnitus, etc.. Complications may be life-threatening and may include progressive kidney dam
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https://en.wikipedia.org/wiki/Pupillary%20distance
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Pupillary distance (PD), more correctly known as interpupillary distance (IPD) is the distance in millimeters between the centers of each pupil.
Interpupillary Distance Classifications
Distance PD is the separation between the visual axes of the eyes in their primary position, as the subject fixates on an infinitely distant object.
Near PD is the separation between the visual axes of the eyes, at the plane of the spectacle lenses, as the subject fixates on a near object at the intended working distance.
Intermediate PD is at a specified plane in between distance and near.
Monocular PD refers to the distance between either the right or left visual axis to the bridge of the nose, which may be slightly different for each eye due to anatomical variations but always sums up to the binocular PD.
For people who need to wear prescription glasses, consideration of monocular PD measurement by an optician helps to ensure that the lenses will be located in the optimum position.
Whilst PD is an optometric term used to specify prescription eyewear, IPD is more critical for the design of binocular viewing systems, where both eye pupils need to be positioned within the exit pupils of the viewing system. These viewing systems include binocular microscopes, night vision devices or goggles (NVGs), and head-mounted displays (HMDs). IPD data are used in the design of such systems to specify the range of lateral adjustment of the exit optics or eyepieces. IPD is also used to describe the distan
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https://en.wikipedia.org/wiki/Dilution%20%28equation%29
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Dilution is the process of decreasing the concentration of a solute in a solution, usually simply by mixing with more solvent like adding more water to the solution. To dilute a solution means to add more solvent without the addition of more solute. The resulting solution is thoroughly mixed so as to ensure that all parts of the solution are identical.
The same direct relationship applies to gases and vapors diluted in air for example. Although, thorough mixing of gases and vapors may not be as easily accomplished.
For example, if there are 10 grams of salt (the solute) dissolved in 1 litre of water (the solvent), this solution has a certain salt concentration (molarity). If one adds 1 litre of water to this solution, the salt concentration is reduced. The diluted solution still contains 10 grams of salt (0.171 moles of NaCl).
Mathematically this relationship can be shown by equation:
where
c1 = initial concentration or molarity
V1 = initial volume
c2 = final concentration or molarity
V2 = final volume
....
Basic room purge equation
The basic room purge equation is used in industrial hygiene. It determines the time required to reduce a known vapor concentration existing in a closed space to a lower vapor concentration. The equation can only be applied when the purged volume of vapor or gas is replaced with "clean" air or gas. For example, the equation can be used to calculate the time required at a certain ventilation rate to reduce a high carbon monoxide concentr
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https://en.wikipedia.org/wiki/Karmarkar%27s%20algorithm
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Karmarkar's algorithm is an algorithm introduced by Narendra Karmarkar in 1984 for solving linear programming problems. It was the first reasonably efficient algorithm that solves these problems in polynomial time. The ellipsoid method is also polynomial time but proved to be inefficient in practice.
Denoting as the number of variables and as the number of bits of input to the algorithm, Karmarkar's algorithm requires operations on -digit numbers, as compared to such operations for the ellipsoid algorithm. The runtime of Karmarkar's algorithm is thus
using FFT-based multiplication (see Big O notation).
Karmarkar's algorithm falls within the class of interior-point methods: the current guess for the solution does not follow the boundary of the feasible set as in the simplex method, but moves through the interior of the feasible region, improving the approximation of the optimal solution by a definite fraction with every iteration and converging to an optimal solution with rational data.
The algorithm
Consider a linear programming problem in matrix form:
Karmarkar's algorithm determines the next feasible direction toward optimality and scales back by a factor . It is described in a number of sources. Karmarkar also has extended the method to solve problems with integer constraints and non-convex problems.
Since the actual algorithm is rather complicated, researchers looked for a more intuitive version of it, and in 1985 developed affine scaling, a version of Karmark
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https://en.wikipedia.org/wiki/Apoptosome
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The apoptosome is a large quaternary protein structure formed in the process of apoptosis. Its formation is triggered by the release of cytochrome c from the mitochondria in response to an internal (intrinsic) or external (extrinsic) cell death stimulus. Stimuli can vary from DNA damage and viral infection to developmental cues such as those leading to the degradation of a tadpole's tail.
In mammalian cells, once cytochrome c is released, it binds to the cytosolic protein Apaf-1 to facilitate the formation of an apoptosome. An early biochemical study suggests a two-to-one ratio of cytochrome c to apaf-1 for apoptosome formation. However, recent structural studies suggest the cytochrome c to apaf-1 ratio is one-to-one. It has also been shown that the nucleotide dATP as third component binds to apaf-1, however its exact role is still debated. The mammalian apoptosome had never been crystallized, but a human APAF-1/cytochrome-c apoptosome has been imaged at lower (2 nm) resolution by cryogenic transmission electron microscopy in 2002, revealing a heptameric wheel-like particle with 7-fold symmetry. Recently, a medium resolution (9.5 Ångström) structure of human apoptosome was also solved by cryo-electron microscopy, which allows unambiguous inference for positions of all the APAF-1 domains (CARD, NBARC and WD40) and cytochrome c. There is also now a crystal structure of the monomeric, inactive Apaf-1 subunit (PDB 3SFZ).
Once formed, the apoptosome can then recruit and activat
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https://en.wikipedia.org/wiki/Agent%20%28economics%29
|
In economics, an agent is an actor (more specifically, a decision maker) in a model of some aspect of the economy. Typically, every agent makes decisions by solving a well- or ill-defined optimization or choice problem.
For example, buyers (consumers) and sellers (producers) are two common types of agents in partial equilibrium models of a single market. Macroeconomic models, especially dynamic stochastic general equilibrium models that are explicitly based on microfoundations, often distinguish households, firms, and governments or central banks as the main types of agents in the economy. Each of these agents may play multiple roles in the economy; households, for example, might act as consumers, as workers, and as voters in the model. Some macroeconomic models distinguish even more types of agents, such as workers and shoppers or commercial banks.
The term agent is also used in relation to principal–agent models; in this case, it refers specifically to someone delegated to act on behalf of a principal.
In agent-based computational economics, corresponding agents are "computational objects modeled as interacting according to rules" over space and time, not real people. The rules are formulated to model behavior and social interactions based on stipulated incentives and information. The concept of an agent may be broadly interpreted to be any persistent individual, social, biological, or physical entity interacting with other such entities in the context of a dynamic multi
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https://en.wikipedia.org/wiki/Outcome
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Outcome may refer to:
Outcome (probability), the result of an experiment in probability theory
Outcome (game theory), the result of players' decisions in game theory
The Outcome, a 2005 Spanish film
An outcome measure (or endpoint) in a clinical trial
The National Outcomes adopted as targets by the Scottish Government
See also
Outcome-based education
Outcomes theory
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https://en.wikipedia.org/wiki/Differential%20extraction
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Differential extraction (also known as differential lysis) refers to the process by which the DNA from two different types of cells can be extracted without mixing their contents. The most common application of this method is the extraction of DNA from vaginal epithelial cells and sperm cells from sexual assault cases in order to determine the DNA profiles of the victim and the perpetrator. Its success is based on the fact that sperm cells pack their DNA using protamines (rather than histones) which are held together by disulfide bonds. The protamines sequester DNA from spermatozoa, making it more resilient to DNA extraction than DNA from epithelial cells.
After determining that sperm cells are present (typically through staining and light microscopy) in a vaginal/rectal sample, the subject's epithelial cells are lysed by a standard DNA extraction method, like a phenol/chloroform extraction and their DNA extracted through normal means. The epithelial DNA in solution is removed and saved, while the sperm cell's DNA precipitates with the attached protamines. Differential extraction uses a chemical called dithiothreitol (DTT) to disrupt the sulfur bonds in the protamines in order to release its DNA. Once the DNA is detached from the protamines, it is prone to standard DNA extraction methods. This creates two different DNA fractions from one sample, that of the victim and that of the perpetrator.
However, the described method is difficult to carry out because it is both very l
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https://en.wikipedia.org/wiki/Stanton%20number
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The Stanton number, St, is a dimensionless number that measures the ratio of heat transferred into a fluid to the thermal capacity of fluid. The Stanton number is named after Thomas Stanton (engineer) (1865–1931). It is used to characterize heat transfer in forced convection flows.
Formula
where
h = convection heat transfer coefficient
ρ = density of the fluid
cp = specific heat of the fluid
u = velocity of the fluid
It can also be represented in terms of the fluid's Nusselt, Reynolds, and Prandtl numbers:
where
Nu is the Nusselt number;
Re is the Reynolds number;
Pr is the Prandtl number.
The Stanton number arises in the consideration of the geometric similarity of the momentum boundary layer and the thermal boundary layer, where it can be used to express a relationship between the shear force at the wall (due to viscous drag) and the total heat transfer at the wall (due to thermal diffusivity).
Mass transfer
Using the heat-mass transfer analogy, a mass transfer St equivalent can be found using the Sherwood number and Schmidt number in place of the Nusselt number and Prandtl number, respectively.
where
is the mass Stanton number;
is the Sherwood number based on length;
is the Reynolds number based on length;
is the Schmidt number;
is defined based on a concentration difference (kg s−1 m−2);
is the velocity of the fluid
Boundary layer flow
The Stanton number is a useful measure of the rate of change of the thermal energy deficit (or excess) in the bound
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https://en.wikipedia.org/wiki/Turing%27s%20proof
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Turing's proof is a proof by Alan Turing, first published in January 1937 with the title "On Computable Numbers, with an Application to the ". It was the second proof (after Church's theorem) of the negation of Hilbert's ; that is, the conjecture that some purely mathematical yes–no questions can never be answered by computation; more technically, that some decision problems are "undecidable" in the sense that there is no single algorithm that infallibly gives a correct "yes" or "no" answer to each instance of the problem. In Turing's own words:
"what I shall prove is quite different from the well-known results of Gödel ... I shall now show that there is no general method which tells whether a given formula U is provable in K [Principia Mathematica]".
Turing followed this proof with two others. The second and third both rely on the first. All rely on his development of typewriter-like "computing machines" that obey a simple set of rules and his subsequent development of a "universal computing machine".
Summary of the proofs
In his proof that the Entscheidungsproblem can have no solution, Turing proceeded from two proofs that were to lead to his final proof. His first theorem is most relevant to the halting problem, the second is more relevant to Rice's theorem.
First proof: that no "computing machine" exists that can decide whether or not an arbitrary "computing machine" (as represented by an integer 1, 2, 3, . . .) is "circle-free" (i.e. goes on printing its number in bin
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https://en.wikipedia.org/wiki/Euler%20number%20%28physics%29
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The Euler number (Eu) is a dimensionless number used in fluid flow calculations. It expresses the relationship between a local pressure drop caused by a restriction and the kinetic energy per volume of the flow, and is used to characterize energy losses in the flow, where a perfect frictionless flow corresponds to an Euler number of 0. The inverse of the Euler number is referred to as the Ruark Number with the symbol Ru.
The Euler number is defined as
where
is the density of the fluid.
is the upstream pressure.
is the downstream pressure.
is a characteristic velocity of the flow.
An alternative definition of the Euler number is given by Shah and Sekulic
where
is the pressure drop
See also
Darcy–Weisbach equation is a different way of interpreting the Euler number
Reynolds number for use in flow analysis and similarity of flows
Cavitation number a similarly formulated number with different meaning
References
Further reading
Dimensionless numbers of fluid mechanics
Fluid dynamics
Leonhard Euler
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https://en.wikipedia.org/wiki/Entropy%3A%20A%20New%20World%20View
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Entropy: A New World View is a non-fiction book by Jeremy Rifkin and Ted Howard, with an Afterword by Nicholas Georgescu-Roegen. It was first published by Viking Press, New York in 1980 ().
A paperback edition was published by Bantam in 1981, in a paperback revised edition, by Bantam Books, in 1989 (). The 1989 revised edition was titled: Entropy: Into the Greenhouse World ().
Contents
In the book the authors analyze the world's economic and social structures by using the first and second laws of thermodynamics. The first and second law of thermodynamics — the second of which is known as the law of entropy — both deal with energy. The authors argue that technological nations are wasting resources such as fossil fuels and minerals at an increasing rate, which if unchecked will lead to the destruction of civilization, which has happened before on a smaller scale to past societies. The authors also argue that the societies wasting resources are exploiting the "Third World", now called "developing nations". The wasting of resources is a parallel to wasting energy in the laws of thermodynamics.
The Book promotes the use of sustainable energy sources and slow resource consumption as the solution to delay or forestall death by entropy including resource wars and the collapse of society.
See also
Collapse: How Societies Choose to Fail or Succeed, by Jared Diamond, which presents a similar set of arguments.
References
External links
Entropy, Algeny & The End of Work a review by
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https://en.wikipedia.org/wiki/Direct%20numerical%20simulation
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A direct numerical simulation (DNS) is a simulation in computational fluid dynamics (CFD) in which the Navier–Stokes equations are numerically solved without any turbulence model. This means that the whole range of spatial and temporal scales of the turbulence must be resolved. All the spatial scales of the turbulence must be resolved in the computational mesh, from the smallest dissipative scales (Kolmogorov microscales), up to the integral scale , associated with the motions containing most of the kinetic energy. The Kolmogorov scale, , is given by
where is the kinematic viscosity and is the rate of kinetic energy dissipation. On the other hand, the integral scale depends usually on the spatial scale of the boundary conditions.
To satisfy these resolution requirements, the number of points along a given mesh direction with increments , must be
so that the integral scale is contained within the computational domain, and also
so that the Kolmogorov scale can be resolved.
Since
where is the root mean square (RMS) of the velocity, the previous relations imply that a three-dimensional DNS requires a number of mesh points satisfying
where is the turbulent Reynolds number:
Hence, the memory storage requirement in a DNS grows very fast with the Reynolds number. In addition, given the very large memory necessary, the integration of the solution in time must be done by an explicit method. This means that in order to be accurate, the integration, for most discretization
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https://en.wikipedia.org/wiki/Intercontinental%20Cup%20records%20and%20statistics
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Statistics for the Intercontinental Cup which ran from 1960 to 2004.
Finals
By country
By team
By continent
After the events of the 1969 Intercontinental Cup, many European Cup champions refused to play in the Intercontinental Cup. On five occasions, they were replaced by the tournament's runners-up. Two Intercontinental Cups were called off after the runners-up also declined to participate.
Man of the Match
Since 1980
See also
Intercontinental Cup
FIFA Club World Cup, the Intercontinental Cup's succeeding competition
Copa Libertadores
UEFA Champions League
Notes
References
Statistics
International club association football competition records and statistics
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https://en.wikipedia.org/wiki/Heinrich%20Wilhelm%20Gottfried%20von%20Waldeyer-Hartz
|
Heinrich Wilhelm Gottfried von Waldeyer-Hartz (6 October 1836 – 23 January 1921) was a German anatomist, known for summarizing neuron theory and for naming the chromosome. He is also remembered by anatomical structures of the human body which were named after him: Waldeyer's tonsillar ring (the lymphoid tissue ring of the naso- and oropharynx) and Waldeyer's glands (of the eyelids).
Contribution to neuron theory
Waldeyer's name is associated in neuroscience with the "neuron theory", and for coining the term "neuron" to describe the basic structural unit of the nervous system. Waldeyer synthesized the discoveries by neuroanatomists (and later Nobel Prize winners) Camillo Golgi (1843–1926) and Santiago Ramón y Cajal (1852–1934), who had used the silver nitrate method of staining nerve tissue (Golgi's method), to formulate widely cited reviews of the theory. Waldeyer learned Spanish in order to absorb Cajal's detailed studies using Golgi's method and became his friend, mentor and promoter in the German-dominated field of microscopic anatomy. The theory was published in a series of papers in the main medical journal of Germany, Deutsche Medizinische Wochenschrift, which became extremely influential. However, as Cajal points out, though Waldeyer "supported the theory with the prestige of his authority, he did not contribute a single personal observation. He limited himself to a short brilliant exposition of the objective proofs, adduced by His, Kölliker, Retzius, van Gehuchten a
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https://en.wikipedia.org/wiki/Peltarion%20Synapse
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Synapse is a component-based development environment for neural networks and adaptive systems. Created by Peltarion, Synapse allows data mining, statistical analysis, visualization, preprocessing, design and training of neural networks and adaptive systems and the deployment of them. It utilizes a plug-in based architecture making it a general platform for signal processing. The first version of the product was released in May 2006.
Platform
Due to its plug in-based design, the usage of Synapse can be very general. Synapse is based on the Microsoft .NET framework and all Synapse components are also .NET components. Although Peltarion has yet to release an official API for the Synapse platform, user made components are emerging, some of them being original, demonstrating the openness of the platform.
Features
The development cycle in Synapse is based on the canonical data mining cycle. A notable difference however is that in Synapse that cycle is not linear, but supports an iterative approach where the user can freely move between the steps. Synapse features four different operating modes that make up the development cycle.
Preprocessing
The preprocessing mode is for data mining and data preparation. In this mode the user can import, visualize, explore and transform data in a variety of ways. Data is imported through the use of format components. The standard release includes format components for reading and writing data from CSV (text) files, SQL databases, images and XM
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https://en.wikipedia.org/wiki/Yeast%20display
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Yeast display (or yeast surface display) is a protein engineering technique that uses the expression of recombinant proteins incorporated into the cell wall of yeast for isolating and engineering antibodies.
Development
The yeast display technique was first published by the laboratory of Professor K. Dane Wittrup and Eric T. Boder. The technology was sold to Abbott Laboratories in 2001.
How it works
A protein of interest is displayed as a fusion to the Aga2p protein on the surface of yeast. The Aga2p protein is naturally used by yeast to mediate cell–cell contacts during yeast cell mating. As such, display of a protein via Aga2p projects the protein away from the cell surface, minimizing potential interactions with other molecules on the yeast cell wall. The use of magnetic separation and flow cytometry in conjunction with a yeast display library is a highly effective method to isolate high affinity protein ligands against nearly any receptor through directed evolution.
Advantages and disadvantages
Advantages of yeast display over other in vitro evolution methods include eukaryotic expression and processing, quality control mechanisms of the eukaryotic secretory pathway, minimal avidity effects, and quantitative library screening through fluorescent-activated cell sorting (FACS). Yeast are eukaryotic organisms that allow for complex post-translational modifications to proteins that no other display libraries are able to provide.
Disadvantages include smaller mutant libr
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https://en.wikipedia.org/wiki/Data%20classification%20%28data%20management%29
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In the field of data management, data classification as a part of the Information Lifecycle Management (ILM) process can be defined as a tool for categorization of data to enable/help organizations to effectively answer the following questions:
What data types are available?
Where are certain data located?
What access levels are implemented?
What protection level is implemented and does it adhere to compliance regulations?
When implemented it provides a bridge between IT professionals and process or application owners. IT staff are informed about the data value and management (usually application owners) understands better which part of the data centre needs to be invested in to keep operations running effectively. This can be of particular importance in risk management, legal discovery, and compliance with government regulations. Data classification is typically a manual process; however, there are many tools from different vendors that can help gather information about the data.
Data classification needs to take into account the following:
Regulatory requirements
Strategic or proprietary worth
Organization specific policies
Ethical and privacy considerations
Contractual agreements
How to start process of data classification?
Note that this classification structure is written from a Data Management perspective and therefore has a focus for text and text convertible binary data sources. Images, videos, and audio files are highly structured formats built for industry
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https://en.wikipedia.org/wiki/Manakov%20system
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Maxwell's Equations, when converted to cylindrical coordinates, and with the boundary conditions for an optical fiber while including birefringence as an effect taken into account, will yield the coupled nonlinear Schrödinger equations. After employing the Inverse scattering transform (a procedure analogous to the Fourier Transform and Laplace Transform) on the resulting equations, the Manakov system is then obtained. The most general form of the Manakov system is as follows:
It is a coupled system of linear ordinary differential equations. The functions represent the envelope of the electromagnetic field as an initial condition.
For theoretical purposes, the integral equation version is often very useful. It is as follows:
One may make further substitutions and simplifications, depending on the limits used and the assumptions about boundary or initial conditions. One important concept is that is complex; assumptions must be made about this eigenvalue parameter. If a non-zero solution is desired, the imaginary part of the eigenvalue cannot change sign; accordingly, most researchers take the imaginary part to be positive.
References
Fiber optics
Ordinary differential equations
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https://en.wikipedia.org/wiki/Frequent%20urination
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Frequent urination, or urinary frequency (sometimes called pollakiuria), is the need to urinate more often than usual. Diuretics are medications that increase urinary frequency. Nocturia is the need of frequent urination at night. The most common cause of this condition for women and children is a urinary tract infection. The most common cause of urinary frequency in older men is an enlarged prostate.
Frequent urination is strongly associated with frequent incidents of urinary urgency, which is the sudden need to urinate. It is often, though not necessarily, associated with urinary incontinence and polyuria (large total volume of urine). However, in other cases, urinary frequency involves only normal volumes of urine overall.
Definition
The normal number of times varies according to the age of the person. Among young children, urinating 8 to 14 times each day is typical. This decreases to 6–12 times per day for older children, and to 4–6 times per day among teenagers.
Causes
The most common causes of frequent urination are:
interstitial cystitis
urinary tract infection
enlarged prostate
urethral inflammation or infection
vaginal inflammation or infection.
Less common causes of frequent urination are:
alcoholism
anxiety
bladder cancer
caffeine
diabetes
pregnancy
psychiatric medications such as clozapine
radiation therapy to the pelvis
brain or nervous system diseases
stroke
tumor in the pelvis
kidney stones.
Diagnosis and treatment
Diagnosis of the unde
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https://en.wikipedia.org/wiki/Triple%20Play%20%28FIRST%29
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Triple Play was the name of the 2005 season FIRST Robotics Competition game.
Basic Description
Triple Play was the FIRST Robotics Competition game released on January 8, 2005. This is the first time the game rules PDF files were made available in late December to teams prior to the official release. The files with an alpha numeric password featuring the game's name. The password was 2005tr1pl3pl4y.
This game was the first to feature three robots per alliance. The primary game pieces were called "Tetras" which are tetrahedra made from PVC pipe long. The game was played on a field set up like a tic-tac-toe board, with nine larger goals, also shaped as tetras in three rows of three. The object of the game was to place the scoring tetras on the larger goals, creating rows of three by having a tetra of your alliance’s color at the highest point on the goal. Triple Play was a strategically intensive game, requiring quick thinking on the part of the drivers and operators to optimize the field for their alliance.
Game play
Tetras scored on the top of a goal were worth 3 points, while tetras contained inside the goals were worth 1 point. A goal was "owned" by the alliance whose color tetra highest on or inside the goal. Rows of three owned goals garnered the alliance an additional 10 points per at the end of regulation play. Ten points could also be scored if all three alliance robots were behind the alliance line at their end of the field at the end of the game.
The playing fi
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https://en.wikipedia.org/wiki/Stupid%20sort
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Stupid sort may refer to:
Bogosort, based on the generate and test paradigm
Gnome sort, similar to insertion sort
Sorting algorithms
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https://en.wikipedia.org/wiki/Detroit%20Sleeper%20Cell
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The Detroit Sleeper Cell is a group of men of Middle-Eastern descent who the United States Department of Justice believed were plotting an attack on Disneyland.
Trial
While on a trip to Disneyland, the four men recorded a home video. The Justice Department believed that this recording was reconnaissance for a future terror attack. This video, combined with the testimony of self-described con-artist Youssef Hmimssa, and what the defense called doodles in a day planner, but the prosecution called terror plans, led to the conviction of two men on June 3, 2003.
The prosecution claimed the five were "Takfiris" — followers of a radical Islamic sect that allowed mujahideen to drink alcohol, use narcotics, and refrain from praying, in order to blend into Western societies, so they could mount clandestine attacks on them.
Youssef Hmimssa, who pleaded guilty to multiple charges of credit card fraud and identity theft, agreed to testify against the four men, in a deal that would allow him to consolidate his other charges, and avoid further charges, reducing his sentence to between 37 and 46 months in prison. Defense attorneys Joseph A. Niskar, James C. Thomas, James Gerometta, Richard Helfrick, William Swor, Margaret Raben, and Robert Morgan were assigned to represent each individual member of the group. However, the attorneys argued the case together.
Post-trial
Later, the conviction of the two men was overturned by information indicating that the prosecution had withheld import
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https://en.wikipedia.org/wiki/Paraphilic%20infantilism
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Paraphilic infantilism, also known as autonepiophilia and adult baby, is a sexual fetish that involves role-playing a regression to an infant-like state. Paraphilic infantilism is a form of ageplay. People who practice paraphilic infantilism are often colloquially referred to (by themselves and others) as "adult babies", or "ABs".
Behaviors may include things such as wearing childish clothes, wearing or using diapers, cuddling with stuffed animals, drinking from a bottle or sucking on a pacifier, and (when done with others) engaging in gentle and nurturing experiences, baby talk, or BDSM power dynamics involving masochism, coercion, punishment or humiliation.
Paraphilic infantilism is often associated with diaper fetishism, a separate but related kink in which people derive sexual pleasure from themselves or others wearing or using diapers, without necessarily involving any form of ageplay. People with a diaper fetish are often informally called "diaper lovers", or "DLs". In practice, these strict labels do not always reflect the true diversity of sexual expression. As such, when considered together, paraphilic infantilism and diaper fetishism form a spectrum of behaviors that are often colloquially referred to under the umbrella term "adult baby/diaper lover", or "AB/DL" (also spelled "ABDL").
Like other sexual fetishes (paraphilias), there is no single recognized cause for paraphilic infantilism and little research has been done on the subject. A variety of theories hav
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https://en.wikipedia.org/wiki/Atmospheric%20dispersion%20modeling
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Atmospheric dispersion modeling is the mathematical simulation of how air pollutants disperse in the ambient atmosphere. It is performed with computer programs that include algorithms to solve the mathematical equations that govern the pollutant dispersion. The dispersion models are used to estimate the downwind ambient concentration of air pollutants or toxins emitted from sources such as industrial plants, vehicular traffic or accidental chemical releases. They can also be used to predict future concentrations under specific scenarios (i.e. changes in emission sources). Therefore, they are the dominant type of model used in air quality policy making. They are most useful for pollutants that are dispersed over large distances and that may react in the atmosphere. For pollutants that have a very high spatio-temporal variability (i.e. have very steep distance to source decay such as black carbon) and for epidemiological studies statistical land-use regression models are also used.
Dispersion models are important to governmental agencies tasked with protecting and managing the ambient air quality. The models are typically employed to determine whether existing or proposed new industrial facilities are or will be in compliance with the National Ambient Air Quality Standards (NAAQS) in the United States and other nations. The models also serve to assist in the design of effective control strategies to reduce emissions of harmful air pollutants. During the late 1960s, the Air Pol
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https://en.wikipedia.org/wiki/Cylindrite
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Cylindrite is a sulfosalt mineral containing tin, lead, antimony and iron with formula: Pb3Sn4FeSb2S14. It forms triclinic pinacoidal crystals which often occur as tubes or cylinders which are in fact rolled sheets. It has a black to lead grey metallic colour with a Mohs hardness of 2 to 3 and a specific gravity of 5.4.
It was first discovered in the Santa Cruz mine, Oruro Department, Bolivia in 1893. The name arises from its curious cylindrical crystal which it forms almost uniquely among minerals.
See also
Classification of minerals
List of minerals
References
Lead minerals
Tin minerals
Iron minerals
Antimony minerals
Sulfosalt minerals
Triclinic minerals
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https://en.wikipedia.org/wiki/Severian
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Severian is the narrator and main character of Gene Wolfe's four-volume science fiction series The Book of the New Sun, as well as its sequel, The Urth of the New Sun. He is a Journeyman of the Seekers for Truth and Penitence (a Guild of torturers) who is exiled after showing mercy to one of his clients.
Severian claims to have perfect memory (his eidetic memory is stated as a fact by Gene Wolfe in Shadows of the New Sun). In spite of this, some critics and analysis claim him to be an unreliable narrator.
Severian's life
Youth
Severian was raised by his guild from birth. His mother was pregnant, when she was imprisoned in Matachin Tower of the torturers. They kept him alive after her death, which was their method for getting new candidates for members of the guild. He led there a sheltered life, not knowing much about the rest of the world.
He did hear about Vodalus - an aristocratic rebel, claiming to fight to restore Urth to its former glory - and accidentally saved the outlaw's life. Severian later idolized Vodalus and wanted to join him, but with time he learnt the bitter truth about him.
Severian starts the novel as an apprentice but shortly becomes the captain of apprentices, and later a Journeyman in the Guild of Torturers. As a boy, he rescues a dog named Triskele, which leads him through secret tunnels to a courtyard belonging to an "exultant" (aristocratic) family, where he meets a girl named Valeria.
While still captain of apprentices, Severian meets and bef
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https://en.wikipedia.org/wiki/Geigerite
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Geigerite is a mineral, a complex hydrous manganese arsenate with formula: Mn5(AsO3OH)2(AsO4)2·10H2O. It forms triclinic pinacoidal, vitreous, colorless to red to brown crystals. It has a Mohs hardness of 3 and a specific gravity of 3.05.
It was discovered in Grischun, Switzerland in 1989. It was named
in honor of Thomas Geiger (1886–1976), Wiesendangen, Switzerland, who studied the Falotta manganese ores.
Composition
The chemical composition of geigerite is hydrous manganese arsenate (Mn5(AsO3OH)2(AsO4)2·10H2O). The chemical composition was found by using an electron microprobe in the Falotta mines in Switzerland.
Geologic occurrence
Geigerite can be found in the abandoned manganese mine in Oberhalbstein, Switzerland. It is mainly found in cavities in adiolarites, which are a form of igneous rock that have either a
radial or fanlike texture of crystals. Geigerite is then formed by metamorphism of manganese
oxide ores. Recently, geigerite has been found in Fukushima Prefecture, Japan. Geigerite has also been found in Mt. Nero Mine, Borghetto Di Vara, La Spieza, Italy.
Structure
Geigerite’s crystal system is triclinic with perfect cleavage on the {010}. The Herman Mauguin symbol for geigerite is and its space group is P. Geigerite contains two arsenate ions which are independent of one another. The first is the AsO3OH group, and the second is the AsO4. In the acidic AsO3OH group, the As-O bonds are much shorter than the As-OH bonds. Similarly, in the AsO4 group, As-O
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https://en.wikipedia.org/wiki/Qualcomm%20Atheros
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Qualcomm Atheros is a developer of semiconductor chips for network communications, particularly wireless chipsets. The company was founded under the name T-Span Systems in 1998 by experts in signal processing and VLSI design from Stanford University, the University of California, Berkeley, and private industry. The company was renamed Atheros Communications in 2000 and it completed an initial public offering in February 2004, trading on the NASDAQ under the symbol ATHR.
On January 5, 2011, it was announced that Qualcomm had agreed to a takeover of the company for a valuation of US$3.7 billion. When the acquisition was completed on May 24, 2011, Atheros became a subsidiary of Qualcomm operating under the name Qualcomm Atheros.
Qualcomm Atheros chipsets for the IEEE 802.11 standard of wireless networking are used by over 30 different wireless device manufacturers.
History
T-Span Systems was co-founded in 1998 by Teresa Meng, professor of engineering at Stanford University and John L. Hennessy, provost at the time and then president of Stanford University through 2016.
The company's first office was a converted house on Encina Avenue, Palo Alto, adjacent to a car wash and Town & Country Village.
In September 1999, the company moved to an office at 3145 Porter Drive, Building A, Palo Alto.
In 2000, T-Span Systems was renamed Atheros Communications and the company moved to a larger office at 529 Almanor Avenue, Sunnyvale. Atheros publicly demonstrated its inaugural chipset, t
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https://en.wikipedia.org/wiki/GLI1
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Zinc finger protein GLI1 also known as glioma-associated oncogene is a protein that in humans is encoded by the GLI1 gene. It was originally isolated from human glioblastoma cells.
Function
The Gli proteins are the effectors of Hedgehog (Hh) signaling and have been shown to be involved in cell fate determination, proliferation and patterning in many cell types and most organs during embryo development. In the developing spinal cord the target genes of Gli proteins, that are themselves transcription factors, are arranged into a complex gene regulatory network that translates the extracellular concentration gradient of Sonic hedgehog into different cell fates along the dorsoventral axis.
The Gli transcription factors activate/inhibit transcription by binding to Gli responsive genes and by interacting with the transcription complex. The Gli transcription factors have DNA binding zinc finger domains which bind to consensus sequences on their target genes to initiate or suppress transcription. Yoon showed that mutating the Gli zinc finger domain inhibited the proteins effect proving its role as a transcription factor. Gli proteins have an 18-amino acid region highly similar to the α-helical herpes simplex viral protein 16 activation domain. This domain contains a consensus recognition element for the human TFIID TATA box-binding protein associated factor TAFII31. Other proteins such as Missing in Metastasis (MIM/BEG4) have been shown to potentiate the effects of the Gli tr
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https://en.wikipedia.org/wiki/GLI2
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Zinc finger protein GLI2 also known as GLI family zinc finger 2 is a protein that in humans is encoded by the GLI2 gene. The protein encoded by this gene is a transcription factor.
GLI2 belongs to the C2H2-type zinc finger protein subclass of the Gli family. Members of this subclass are characterized as transcription factors which bind DNA through zinc finger motifs. These motifs contain conserved H-C links. Gli family zinc finger proteins are mediators of Sonic hedgehog (Shh) signaling and they are implicated as potent oncogenes in the embryonal carcinoma cell. The protein encoded by this gene localizes to the cytoplasm and activates patched Drosophila homolog (PTCH) gene expression. It is also thought to play a role during embryogenesis.
Isoforms
There are four isoforms: Gli2 alpha, beta, gamma and delta.
Structure
C-terminal activator and N-terminal repressor regions have been identified in both Gli2 and Gli3. However, the N-terminal part of human Gli2 is much smaller than its mouse or frog homologs, suggesting that it may lack repressor function.
Function
Gli2 affects ventroposterior mesodermal development by regulating at least three different genes; Wnt genes involved in morphogenesis, Brachyury genes involved in tissue specification and Xhox3 genes involved in positional information. The anti-apoptotic protein BCL-2 is up regulated by Gli2 and, to a lesser extent, Gli1 – but not Gli3, which may lead to carcinogenesis. Additionally, in the amphibian model organis
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https://en.wikipedia.org/wiki/GLI3
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Zinc finger protein GLI3 is a protein that in humans is encoded by the GLI3 gene.
This gene encodes a protein that belongs to the C2H2-type zinc finger proteins subclass of the Gli family. They are characterized as DNA-binding transcription factors and are mediators of Sonic hedgehog (Shh) signaling. The protein encoded by this gene localizes in the cytoplasm and activates patched Drosophila homolog (PTCH1) gene expression. It is also thought to play a role during embryogenesis.
Role in development
Gli3 is a known transcriptional repressor but may also have a positive transcriptional function. Gli3 represses dHand and Gremlin, which are involved in developing digits. There is evidence that Shh-controlled processing (e.g., cleavage) regulates transcriptional activity of Gli3 similarly to that of Ci. Gli3 mutant mice have many abnormalities including CNS and lung defects and limb polydactyly. In the developing mouse limb bud, Gli3 derepression predominantly regulates Shh target genes.
Disease association
Mutations in this gene have been associated with several diseases, including Greig cephalopolysyndactyly syndrome, Pallister–Hall syndrome, preaxial polydactyly type IV, and postaxial polydactyly types A1 and B. DNA copy-number alterations that contribute to increased conversion of the oncogenes Gli1–3 into transcriptional activators by the Hedgehog signaling pathway are included in a genome-wide pattern, which was found to be correlated with an astrocytoma patient's ou
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https://en.wikipedia.org/wiki/Ocular%20dominance%20column
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Ocular dominance columns are stripes of neurons in the visual cortex of certain mammals (including humans) that respond preferentially to input from one eye or the other. The columns span multiple cortical layers, and are laid out in a striped pattern across the surface of the striate cortex (V1). The stripes lie perpendicular to the orientation columns.
Ocular dominance columns were important in early studies of cortical plasticity, as it was found that monocular deprivation causes the columns to degrade, with the non-deprived eye assuming control of more of the cortical cells.
It is believed that ocular dominance columns must be important in binocular vision. Surprisingly, however, many squirrel monkeys either lack or partially lack ocular dominance columns, which would not be expected if they are useful. This has led some to question whether they serve a purpose, or are just a byproduct of development.
History
Discovery
Ocular dominance columns were discovered in the 1960s by Hubel and Wiesel as part of their Nobel prize winning work on the structure of the visual cortex in cats. Ocular dominance columns have since been found in many animals, such as ferrets, macaques, and humans. Notably, they are also absent in many animals with binocular vision, such as rats.
Structure
Ocular dominance columns are stripe shaped regions of the primary visual cortex that lie perpendicular to the orientation columns, as can be seen in the accompanying figure. Different species have
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https://en.wikipedia.org/wiki/List%20of%20ICD-9%20codes%20E%20and%20V%20codes%3A%20external%20causes%20of%20injury%20and%20supplemental%20classification
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(E000) External cause status
External cause status
Civilian activity done for income or pay
Military activity
Volunteer activity
Other external cause status
Unspecified external cause status
(E001–E030) Activity
Activities involving walking and running
Activities involving water and water craft
Activities involving snow and ice
Activities involving climbing, rappelling and jumping off
Activities involving dancing and other rhythmic movement
Activities involving other sports and athletics played individually
Activities involving other sports and athletics played as a team or group
Activities involving other specified sports and athletics
Activity involving other cardiorespiratory exercise
Activity involving other muscle strengthening exercises
Activities involving computer technology and electronic devices
Activities involving arts and handcrafts
Activities involving personal hygiene and household maintenance
Activities involving person providing caregiving
Activities involving food preparation, cooking and grilling
Activities involving property and land maintenance, building and construction
Activities involving roller coasters and other types of external motion
Activities involving playing musical instrument
Activities involving animal care
Other activity
Unspecified activity
(E800–E807) Railway accidents
Railway accident involving collision with rolling stock
Railway accident involving collision with other object
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https://en.wikipedia.org/wiki/Additive%20increase/multiplicative%20decrease
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The additive-increase/multiplicative-decrease (AIMD) algorithm is a feedback control algorithm best known for its use in TCP congestion control. AIMD combines linear growth of the congestion window when there is no congestion with an exponential reduction when congestion is detected. Multiple flows using AIMD congestion control will eventually converge to an equal usage of a shared link. The related schemes of multiplicative-increase/multiplicative-decrease (MIMD) and additive-increase/additive-decrease (AIAD) do not reach stability.
Algorithm
The approach taken is to increase the transmission rate (window size), probing for usable bandwidth, until loss occurs. The policy of additive increase may, for instance, increase the congestion window by a fixed amount every round-trip time. When congestion is detected, the transmitter decreases the transmission rate by a multiplicative factor; for example, cut the congestion window in half after loss. The result is a saw-tooth behavior that represents the process of bandwidth probing.
AIMD requires a binary congestion signal. Most frequently, packet loss serves as the signal; the multiplicative decrease is triggered when a timeout or an acknowledgement message indicates a packet lost. It is also possible for in-network switches/routers to mark congestion (without discarding packets) as in Explicit Congestion Notification (ECN).
Mathematical Formula
Let be the congestion window size indicating the amount of data in flight durin
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https://en.wikipedia.org/wiki/Electrical%20characteristics%20of%20dynamic%20loudspeakers
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The chief electrical characteristic of a dynamic loudspeaker's driver is its electrical impedance as a function of frequency. It can be visualized by plotting it as a graph, called the impedance curve.
Explanation
The most common driver type is an electro-mechanical transducer using a voice coil rigidly connected to a diaphragm (generally a cone). Other types have similar connections, though differing in detail, between their acoustical environment and their electrical properties.
The voice coil in moving coil drivers is suspended in a magnetic field provided by the loudspeaker magnet structure. As electric current flows through the voice coil (from an electronic amplifier), the magnetic field created by the coil reacts against the magnet's fixed field and moves the voice coil (and so the cone). Alternating current will move the cone back and forth.
Resonance
The moving system of the loudspeaker—consisting of the cone, cone suspension, spider, and voice coil—can be modeled as an effective mass (spring–mass system), a mass suspended by a spring. This system has a characteristic mass and stiffness, and a resonant frequency at which the system will vibrate freely.
This frequency is known as the "free-space resonance" of the loudspeaker and is designated by Fs. At this frequency, the voice coil is vibrating in the speaker's magnetic field with maximum peak-to-peak amplitude and velocity. The back EMF generated by this movement is also at its maximum. The electrical impeda
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https://en.wikipedia.org/wiki/Torricelli%27s%20law
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Torricelli's law, also known as Torricelli's theorem, is a theorem in fluid dynamics relating the speed of fluid flowing from an orifice to the height of fluid above the opening. The law states that the speed of efflux of a fluid through a sharp-edged hole at the bottom of the tank filled to a depth is the same as the speed that a body (in this case a drop of water) would acquire in falling freely from a height , i.e. , where is the acceleration due to gravity. This expression comes from equating the kinetic energy gained, , with the potential energy lost, , and solving for . The law was discovered (though not in this form) by the Italian scientist Evangelista Torricelli, in 1643. It was later shown to be a particular case of Bernoulli's principle.
Derivation
Under the assumptions of an incompressible fluid with negligible viscosity, Bernoulli's principle states that the hydraulic energy is constant
at any two points in the flowing liquid. Here is fluid speed, is the acceleration due to gravity, is the height above some reference point, is the pressure, and is the density.
In order to derive Torricelli's formula the first point with no index is taken at the liquid's surface, and the second just outside the opening. Since the liquid is assumed to be incompressible, is equal to and ; both can be represented by one symbol . The pressure and are typically both atmospheric pressure, so . Furthermore
is equal to the height of the liquid's surface over the openin
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https://en.wikipedia.org/wiki/Linear%20Technology
|
Linear Technology Corporation was an American semiconductor company that designed, manufactured and marketed high performance analog integrated circuits. Applications for the company's products included telecommunications, cellular telephones, networking products, notebook and desktop computers, video/multimedia, industrial instrumentation, automotive electronics, factory automation, process control, military and space systems. The company was founded in 1981 by Robert H. Swanson, Jr. and Robert C. Dobkin.
In July 2016, Analog Devices agreed to buy Linear Technology for 14.8 billion dollars. This acquisition was finalized on March 10, 2017. The Linear name survives as the "Power by Linear" brand that is used to market the combined power management portfolios of Linear Technology and Analog Devices.
Products
As of August 2010, the company made over 7500 products, which they organized into seven product categories: data conversion (analog to digital converters, digital to analog converters), signal conditioning (operational amplifiers, comparators, voltage references), power management (switching regulators, linear regulators, battery management, LED drivers), interface (RS232, RS485), radio frequency (mixers, quadrature modulators), oscillators, and space and military ICs.
The company maintained LTspice, a freely downloadable version of SPICE that includes schematic capture.
Locations
Corporate headquarters were in Milpitas, California. In the United States, the company
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https://en.wikipedia.org/wiki/96.5%20Inner%20FM
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96.5 Inner FM (official call sign 3INR) is a community radio station in Melbourne, Victoria, Australia.
Profile
96.5 Inner FM broadcasts on a frequency of 96.5 MHz. Its main coverage area is the inner north eastern suburbs of Melbourne. Its format consists of largely of easy listening / nostalgic music, and community programs.
The studios of Inner FM are located at Warringal Shopping Centre (formerly called Centro Warringal) in Burgundy St, Heidelberg. The transmitter is at the Austin Hospital, with signal transmission between station and transmitter achieved by an analogue "line-of-sight" UHF link at a frequency of 847 MHz. For more about this link, see these links here.
Inner FM is staffed by non-paid volunteers, who are involved in all aspects of running the station. Overall management rests with a committee elected by the members. (This is in accord with the proper form for an Incorporated Not-For-Profit association, constituted under the Associations Incorporations Act 1981 (Victoria).)
Inner FM broadcasts 24 hours a day, seven days a week. The format is a mixture of magazine-style and music programmes, with an intention to appeal to all tastes and age groups. Currently, live broadcasting is from 6 am to midnight, with pre-recorded programs overnight on weeknights.
Inner FM can also be listened to through a live audio stream, accessible via the station's website.
A survey conducted by the Department of Transport and Communications in 1992 showed a 40% overall aw
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https://en.wikipedia.org/wiki/Sclerostin
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Sclerostin is a protein that in humans is encoded by the SOST gene. It is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Sclerostin is produced primarily by the osteocyte but is also expressed in other tissues, and has anti-anabolic effects on bone formation.
Structure
The sclerostin protein, with a length of 213 residues, has a secondary structure that has been determined by protein NMR to be 28% beta sheet (6 strands; 32 residues).
Function
Sclerostin, the product of the SOST gene, located on chromosome 17q12–q21 in humans, was originally believed to be a non-classical bone morphogenetic protein (BMP) antagonist. More recently, sclerostin has been identified as binding to LRP5/6 receptors and inhibiting the Wnt signaling pathway. The inhibition of the Wnt pathway leads to decreased bone formation. Although the underlying mechanisms are unclear, it is believed that the antagonism of BMP-induced bone formation by sclerostin is mediated by Wnt signaling, but not BMP signaling pathways. Sclerostin is expressed in osteocytes and some chondrocytes and it inhibits bone formation by osteoblasts.
Sclerostin production by osteocytes is inhibited by parathyroid hormone, mechanical loading, estrogen and cytokines including prostaglandin E2, oncostatin M, cardiotrophin-1 and leukemia inhibitory fa
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https://en.wikipedia.org/wiki/Philippides
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Philippides is a Greek name meaning "Son of Philip"; Philip means "lover of horses". Derivative, patronym, of the more common ancient Greek name "Philippos" Notable people with this name include:
Pheidippides, also known as Philippides, said to have run from Marathon to Athens bringing news of the Greek victory at the battle of Marathon
Philippides (comic poet), flourished 336-333 BC.
Philippides of Paiania, fl. 293/2 BC, wealthy Athenian oligarch
Mary Zelia Pease Philippides (1906–2009), American archaeologist and librarian
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https://en.wikipedia.org/wiki/Richard%20Leigh%20%28songwriter%29
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Richard Leigh (born May 26, 1951 in Washington, D.C.) is an American country music songwriter and singer. He is best known for penning "Don't It Make My Brown Eyes Blue" (sung by Crystal Gayle). In 1978, he received a Grammy Award for "Best Country Song" for the popular song. It was nominated in both pop and country categories and reached number one on both charts.
His first number one song was "I'll Get Over You" (1976), also sung by Crystal Gayle. Other prominent singers who have brought his songs number one status over the years include Billy Dean, Mickey Gilley, Reba McEntire, Barbara Mandrell, Steve Wariner, and Don Williams. Kathy Mattea had another number one hit with "Come From the Heart" in 1990. In 1999, the Dixie Chicks recorded Leigh's "Cold Day in July" for their album Fly, reaching Number 10 on the country music charts in 2000.
Leigh was raised in Virginia, and lives in Tennessee. He is a graduate of Virginia Highlands Community College and Virginia Commonwealth University. It was while he was attending VCU that he penned and first sang "I'll Get Over You," while performing at the Crossroads Coffeehouse in Richmond, Virginia's Fan District. He has been nominated for songwriter of the year seven times and in 1994 he was inducted into the Nashville Songwriters Foundation Hall of Fame. On April 11, 2011, Leigh was one of only four chosen nationally from the American Community College System to be awarded 2011 AACC Outstanding Alumni Award for excellence in ones
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https://en.wikipedia.org/wiki/URB597
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URB597 (KDS-4103) is a relatively selective and irreversible inhibitor of the enzyme fatty acid amide hydrolase (FAAH). FAAH is the primary degradatory enzyme for the endocannabinoid anandamide and, as such, inhibition of FAAH leads to an accumulation of anandamide in the CNS and periphery where it activates cannabinoid receptors. URB597 has been found to elevate anandamide levels and have activity against neuropathic pain in a mouse model.
Preclinical studies have shown FAAH inhibitors to increase BDNF levels in the hippocampus and prefrontal cortex, highlighting their potential in addiction treatment as "enviromimetics". Indeed, Chauvet et al. found that chronic URB597 administration in rats "significantly reduces cocaine-seeking behaviour and cue- and stress-induced relapse".
URB597 was at one point being developed by Kadmus Pharmaceuticals, Inc. for clinical trials in humans.
See also
FAAH
4-Nonylphenylboronic acid
LY-2183240
PF-04457845
References
External links
Modulation of anxiety through blockade of anandamide hydrolysis in Nature
Antidepressants
Benzamides
Phenol esters
Carbamates
Endocannabinoid reuptake inhibitors
Biphenyls
Cyclohexyl compounds
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https://en.wikipedia.org/wiki/Single%20frequency%20approach
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In aviation, a single frequency approach (SFA) is a service for a military single-piloted turbojet aircraft to use a single UHF frequency during their landing approach. Circumstances permitting, pilots will not be required to change their frequency when they switch from ARTCC to terminal facility control when conducting an SFA.
In the U.S., per the FAA, controllers are not allowed to require a frequency change from aircraft conducting an SFA unless:
Pilot has completed landing or low approach
Aircraft is in VFR conditions during daylight hours
Pilot requests a frequency change
Emergency situation exists
Aircraft is cleared for a visual approach
Pilot cancels their IFR flight plan
If a change of control is necessary, controllers will hand off the frequency to each other, instead of having the pilots change the frequency on their radio.
Airbands
American military aviation
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https://en.wikipedia.org/wiki/Haut-Brion
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Haut-Brion is a name found in several Bordeaux wine producers in the Graves district, including:
Château Haut-Brion, a premier cru selection of the 1855 classification then named simply Haut-Brion
Château Laville Haut-Brion, a grand cru of the Graves classification
Château La Mission Haut-Brion, a grand cru of the Graves classification
Château La Tour Haut-Brion, formerly a grand cru, now discontinued
Château Les Carmes Haut-Brion, an unclassed Pessac-Léognan estate
Château Larrivet-Haut-Brion, an unclassed Pessac-Léognan estate
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https://en.wikipedia.org/wiki/Anatole%20Abragam
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Anatole Abragam (15 December 1914 – 8 June 2011) was a French physicist who wrote The Principles of Nuclear Magnetism and made significant contributions to the field of nuclear magnetic resonance. Originally from Griva, Courland Governorate, Russian Empire, Abragam and his family emigrated to France in 1925.
Education
After being educated at the University of Paris, (1933–1936), he served in the Second World War. After the war, he resumed his studies at the École Supérieure d'Électricité and subsequently obtained his Ph.D. from the University of Oxford in 1950 under the supervision of Maurice Pryce.
Career and research
In 1976, he was made an Honorary Fellow of Merton College, Oxford, Magdalen College, Oxford, and Jesus College, Oxford. From 1960 to 1985, he worked as a professor at the .
Awards and honors
Abragam won the Fernand Holweck Medal and Prize in 1958.
Abragam was elected a Foreign Honorary Member of the American Academy of Arts and Sciences in 1974.
He was awarded the Lorentz Medal in 1982.
He was elected a Foreign Member of the Royal Society (ForMemRS) in 1983.
Publications
Abragam A & Bleaney B. Electron paramagnetic resonance of transition ions. Oxford, England: Oxford University Press, 1970.
References
External links
Anatole Abragam. 15 December 1914 — 8 June 2011 Biographial Memoirs of Fellows of the Royal Society
1914 births
2011 deaths
Scientists from Daugavpils
People from Courland Governorate
20th-century Latvian Jews
Latvian emigrants to Franc
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https://en.wikipedia.org/wiki/Michael%20Swann
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Michael Meredith Swann, Baron Swann, (1 March 1920 – 22 September 1990) was a British molecular and cell biologist. He was appointed chairman of the BBC, awarded a knighthood and subsequently a life peerage.
Early life
Swann was born in Cambridge, the eldest of three children of pathologist Meredith Blake Robson Swann and his wife, Marjorie Dykes.
Swann was educated at King's College School, Cambridge, and then at Winchester College, a boarding independent school for boys in the city of Winchester in Hampshire, where he was an Exhibitioner. He then studied zoology at Gonville and Caius College, Cambridge, where he graduated MA.
Life and works
He served with the British Army during World War II, rising to the rank of lieutenant colonel, and being Mentioned in Dispatches. From 1946 Swann lectured in zoology at the University of Cambridge, his alma mater.
He moved to Edinburgh University as professor of natural history in 1952. In 1953 he was elected a fellow of the Royal Society of Edinburgh. His proposers were James Ritchie, John Gaddum, Sir Maurice Yonge and Harold Callan. He won the society's Makdougall Brisbane Prize for 1970/72. In 1962 he was elected a fellow of the Royal Society of London.
His academic work was on the mechanisms of cell division and fertilisation. He used cell polarisation methods to understand the changes in molecular organisation of the mitotic spindle. With his collaborator Murdoch Mitchison, he found evidence in support of a new theory of cell
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https://en.wikipedia.org/wiki/GLUT4
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Glucose transporter type 4 (GLUT4), also known as solute carrier family 2, facilitated glucose transporter member 4, is a protein encoded, in humans, by the SLC2A4 gene. GLUT4 is the insulin-regulated glucose transporter found primarily in adipose tissues and striated muscle (skeletal and cardiac). The first evidence for this distinct glucose transport protein was provided by David James in 1988. The gene that encodes GLUT4 was cloned and mapped in 1989.
At the cell surface, GLUT4 permits the facilitated diffusion of circulating glucose down its concentration gradient into muscle and fat cells. Once within cells, glucose is rapidly phosphorylated by glucokinase in the liver and hexokinase in other tissues to form glucose-6-phosphate, which then enters glycolysis or is polymerized into glycogen. Glucose-6-phosphate cannot diffuse back out of cells, which also serves to maintain the concentration gradient for glucose to passively enter cells.
Structure
Like all proteins, the unique amino acid arrangement in the primary sequence of GLUT4 is what allows it to transport glucose across the plasma membrane. In addition to the phenylalanine on the N-terminus, two Leucine residues and acidic motifs on the COOH-terminus are believed to play a key role in the kinetics of endocytosis and exocytosis.
Other GLUT proteins
There are 14 total GLUT proteins separated into 3 classes based on sequence similarities. Class 1 consists of GLUT 1-4 and 14, class 2 contains GLUT 5, 7, 9 and 1
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https://en.wikipedia.org/wiki/Martingale%20representation%20theorem
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In probability theory, the martingale representation theorem states that a random variable that is measurable with respect to the filtration generated by a Brownian motion can be written in terms of an Itô integral with respect to this Brownian motion.
The theorem only asserts the existence of the representation and does not help to find it explicitly; it is possible in many cases to determine the form of the representation using Malliavin calculus.
Similar theorems also exist for martingales on filtrations induced by jump processes, for example, by Markov chains.
Statement
Let be a Brownian motion on a standard filtered probability space and let be the augmented filtration generated by . If X is a square integrable random variable measurable with respect to , then there exists a predictable process C which is adapted with respect to such that
Consequently,
Application in finance
The martingale representation theorem can be used to establish the existence
of a hedging strategy.
Suppose that is a Q-martingale process, whose volatility is always non-zero.
Then, if is any other Q-martingale, there exists an -previsible process , unique up to sets of measure 0, such that with probability one, and N can be written as:
The replicating strategy is defined to be:
hold units of the stock at the time t, and
hold units of the bond.
where is the stock price discounted by the bond price to time and is the expected payoff of the option at time .
At the expiration day
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https://en.wikipedia.org/wiki/Arid%20Lands%20Ecology%20Reserve
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The Arid Land Ecology Reserve (ALE) is the largest tract of shrub-steppe ecosystem remaining in the U.S. state of Washington. It is managed for the U.S. Department of Energy by the Pacific Northwest National Laboratory (which is operated for the U.S. Department of Energy by Battelle Memorial Institute). The 320 km² area is a portion of the 1500 km² National Environmental Research Park located on the Hanford Site on the northwest boundary of Richland, Washington.
On June 27, 2000, a range fire destroyed most of the native sagebrush and bunchgrass as well as damaged the microbiotic crust. Though the US Fish and Wildlife Service has attempted to re-introduce native flora, the Arid Lands Ecology Reserve is currently dominated by non-native species such as cheatgrass, knapweeds, and Russian thistle (tumbleweed) which flourished after the 2000 fire. Other species such as spiny hop sage and Wyoming big sagebrush were decimated by the fire and in its aftermath.
Vegetation
Shrub-steppe
This vegetation type describes plant communities found in and around arid mountains, ridges and slopes. In the ALE this includes shrubs (sagebrush and rabbit brush), perennial bunchgrasses (Sandberg's blue grass and bluebunch wheat grass) as well as both annual and perennial forbs (balsamroot, phlox and fleabane).
Riparian
This vegetation type refers to plant communities located around springs and streamflow. In the ALE these areas are dominated by willow, black cottonwood, chokecherry, and mock
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https://en.wikipedia.org/wiki/Primer%20extension
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Primer extension is a technique whereby the 5' ends of RNA can be mapped - that is, they can be sequenced and properly identified.
Primer extension can be used to determine the start site of transcription (the end site cannot be determined by this method) by which its sequence is known. This technique requires a radiolabelled primer (usually 20 - 50 nucleotides in length) which is complementary to a region near the 3' end of the mRNA. The primer is allowed to anneal to the RNA and reverse transcriptase is used to synthesize cDNA from the RNA until it reaches the 5' end of the RNA. By denaturing the hybrid and using the extended primer cDNA as a marker on an electrophoretic gel, it is possible to determine the transcriptional start site. It is usually done so by comparing its location on the gel with the DNA sequence (e.g. Sanger sequencing), preferably by using the same primer on the DNA template strand. The exact nucleotide by which the transcription starts at can be pinpointed by matching the labelled extended primer with the marker nucleotide, who are both sharing the same migration distance on the gel.
Primer extension offers an alternative to a nuclease protection assay (S1 nuclease mapping) for quantifying and mapping RNA transcripts. The hybridization probe for primer extension is a synthesized oligonucleotide, whereas S1 mapping requires isolation of a DNA fragment. Both methods provide information where a mRNA starts and provide an estimate of the concentration o
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https://en.wikipedia.org/wiki/Kronecker%27s%20lemma
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In mathematics, Kronecker's lemma (see, e.g., ) is a result about the relationship between convergence of infinite sums and convergence of sequences. The lemma is often used in the proofs of theorems concerning sums of independent random variables such as the strong Law of large numbers. The lemma is named after the German mathematician Leopold Kronecker.
The lemma
If is an infinite sequence of real numbers such that
exists and is finite, then we have for all and that
Proof
Let denote the partial sums of the x'''s. Using summation by parts,
Pick any ε > 0. Now choose N so that is ε-close to s for k > N. This can be done as the sequence converges to s. Then the right hand side is:
Now, let n go to infinity. The first term goes to s, which cancels with the third term. The second term goes to zero (as the sum is a fixed value). Since the b'' sequence is increasing, the last term is bounded by .
References
Mathematical series
Lemmas
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https://en.wikipedia.org/wiki/Mutation%20frequency
|
Mutation frequency and mutation rates are highly correlated to each other. Mutation frequencies test are cost effective in laboratories however; these two concepts provide vital information in reference to accounting for the emergence of mutations on any given germ line.
There are several test utilized in measuring the chances of mutation frequency and rates occurring in a particular gene pool. Some of the test are as follows:
Avida Digital Evolution Platform
Fluctuation Analysis
Mutation frequency and rates provide vital information about how often a mutation may be expressed in a particular genetic group or sex. Yoon et., 2009 suggested that as sperm donors ages increased the sperm mutation frequencies increased. This reveals the positive correlation in how males are most likely to contribute to genetic disorders that reside within X-linked recessive chromosome.
There are additional factors affecting mutation frequency and rates involving evolutionary influences. Since, organisms may pass mutations to their offspring incorporating and analyzing the mutation frequency and rates of a particular species may provide a means to adequately comprehend its longevity
Aging
The time course of spontaneous mutation frequency from middle to late adulthood was measured in four different tissues of the mouse. Mutation frequencies in the cerebellum (90% neurons) and male germ cells were lower than in liver and adipose tissue. Furthermore, the mutation frequencies increased wi
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