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bio-NER-relations

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DerHautarzt.70480297.eng.abstr
DerHautarzt.70480297.eng.abstr
[ { "id": "DerHautarzt.70480297.eng.abstr-passage-0", "type": "abstract", "text": [ "About 95% of individuals who come in contact with M. leprae do not develop overt disease . The clinical form of the disease correlates with the T-cell mediated immune response of the host rather the direct damage caused by bacilli . We review the current aspects of epidemiology , transmission , bacteriology , clinical features , reactions , diagnosis , chemotherapy and treatment of reactions ." ], "offsets": [ [ 0, 396 ] ] } ]
[ { "id": "DerHautarzt.70480297.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 81, 88 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerHautarzt.70480297.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "M. leprae" ], "offsets": [ [ 50, 59 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026922" } ] }, { "id": "DerHautarzt.70480297.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "form" ], "offsets": [ [ 104, 108 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376315" } ] }, { "id": "DerHautarzt.70480297.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 116, 123 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerHautarzt.70480297.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "T-cell" ], "offsets": [ [ 144, 150 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039194" } ] }, { "id": "DerHautarzt.70480297.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "direct" ], "offsets": [ [ 199, 205 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0700157" } ] }, { "id": "DerHautarzt.70480297.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "bacilli" ], "offsets": [ [ 223, 230 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004587" } ] }, { "id": "DerHautarzt.70480297.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "epidemiology" ], "offsets": [ [ 266, 278 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014507" }, { "db_name": "UMLS", "db_id": "C0014508" } ] }, { "id": "DerHautarzt.70480297.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "transmission" ], "offsets": [ [ 281, 293 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040722" } ] }, { "id": "DerHautarzt.70480297.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "bacteriology" ], "offsets": [ [ 296, 308 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220790" }, { "db_name": "UMLS", "db_id": "C0004644" } ] }, { "id": "DerHautarzt.70480297.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 343, 352 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "DerHautarzt.70480297.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "chemotherapy" ], "offsets": [ [ 355, 367 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013216" }, { "db_name": "UMLS", "db_id": "C0013217" } ] }, { "id": "DerHautarzt.70480297.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 372, 381 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] } ]
[]
[]
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"arg2_id": "DerHautarzt.70480297.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerHautarzt.70480297.eng.abstr-s3-r20-t4.1-t1.1", "type": "method_of", "arg1_id": "DerHautarzt.70480297.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.70480297.eng.abstr-s3-t1", "normalized": [] } ]
DerHautarzt.70480303.eng.abstr
DerHautarzt.70480303.eng.abstr
[ { "id": "DerHautarzt.70480303.eng.abstr-passage-0", "type": "abstract", "text": [ "Fatty acids play a central role among the epidermal lipids because of their considerable contribution to structural and functional features of the epidermis . They are important components of cell membranes , the intercellular stratum corneum lipids and the hydro-lipid skin surface film . Additionally , endogenous fatty acids act as mediators of the epidermal cell proliferation and differentiation and therefore , lipid synthesis and also as mediators of inflammatory and immunological processes ." ], "offsets": [ [ 0, 500 ] ] } ]
[ { "id": "DerHautarzt.70480303.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "acids" ], "offsets": [ [ 6, 11 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001128" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "role" ], "offsets": [ [ 27, 31 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035820" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "lipids" ], "offsets": [ [ 52, 58 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023779" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "epidermis" ], "offsets": [ [ 147, 156 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014520" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "Fatty acids" ], "offsets": [ [ 0, 11 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015684" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 192, 196 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "membranes" ], "offsets": [ [ 197, 206 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025255" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "lipids" ], "offsets": [ [ 243, 249 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023779" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "hydro-lipid" ], "offsets": [ [ 258, 269 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020239" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "hydro-lipid" ], "offsets": [ [ 258, 269 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023779" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 270, 274 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "film" ], "offsets": [ [ 283, 287 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0086296" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "cell membranes" ], "offsets": [ [ 192, 206 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007603" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "acids" ], "offsets": [ [ 322, 327 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001128" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "mediators" ], "offsets": [ [ 335, 344 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0127400" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 362, 366 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "lipid" ], "offsets": [ [ 417, 422 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023779" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "mediators" ], "offsets": [ [ 445, 454 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0127400" } ] }, { "id": "DerHautarzt.70480303.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "fatty acids" ], "offsets": [ [ 316, 327 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015684" } ] } ]
[]
[]
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"normalized": [] }, { "id": "DerHautarzt.70480303.eng.abstr-s1-r6-t5.1-t1.1", "type": "interacts_with", "arg1_id": "DerHautarzt.70480303.eng.abstr-s3-t5", "arg2_id": "DerHautarzt.70480303.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerHautarzt.70480303.eng.abstr-s1-r7-t4.1-t5.1", "type": "produces", "arg1_id": "DerHautarzt.70480303.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.70480303.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerHautarzt.70480303.eng.abstr-s1-r8-t1.1-t3.1", "type": "interacts_with", "arg1_id": "DerHautarzt.70480303.eng.abstr-s3-t1", "arg2_id": "DerHautarzt.70480303.eng.abstr-s3-t3", "normalized": [] }, { "id": "DerHautarzt.70480303.eng.abstr-s1-r9-t5.1-t3.1", "type": "interacts_with", "arg1_id": "DerHautarzt.70480303.eng.abstr-s3-t5", "arg2_id": "DerHautarzt.70480303.eng.abstr-s3-t3", "normalized": [] }, { "id": "DerHautarzt.70480303.eng.abstr-s2-r1-t2.1-t3.1", "type": "produces", "arg1_id": "DerHautarzt.70480303.eng.abstr-s3-t2", "arg2_id": 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DerHautarzt.70480318.eng.abstr
DerHautarzt.70480318.eng.abstr
[ { "id": "DerHautarzt.70480318.eng.abstr-passage-0", "type": "abstract", "text": [ "We report about a new type of physical therapy which can be used in patients with joint immobility secondary to by chronic venous insufficiency . Biomechanical stimulation therapy ( BMS ) uses mechanical vibration of standardised frequencies from 18-35 Hz spectrum to expose the feet and legs to longitudinal mechanical stimuli . Therapeutic benefit and clinical improvement can be achieved after a short period of treatment . We describe a 76 year old female patient suffering from both impaired motion and recurrent venous ulceration due to chronic venous insufficiency . After 10 days treatment with BMS , mobility of upper ankle joints improved by 16 degrees and 19 degrees and was accompained by healing of venous ulcerations after skin flap transplantation . Biomechanical stimulation methods were developed in the former Sowiet Union where they were used in sports medicine to improve relaxation of strained muscle structures and to increase the stretching ability of capsules and tendons . We have successfuly treated 6 patients with impaired mobility and chronic venous insufficiency . We believe that BMS is lialy to become a valuable therapeutic tool in patients with this problem in the near future ." ], "offsets": [ [ 0, 1212 ] ] } ]
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[]
[]
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DerHautarzt.70480323.eng.abstr
DerHautarzt.70480323.eng.abstr
[ { "id": "DerHautarzt.70480323.eng.abstr-passage-0", "type": "abstract", "text": [ "Twelve patients with extensive lichen planus , resistant to different regimes of prior external and internal therapy , were treated with PUVA-bath photochemotherapy ( psoralen bath followed by UVA irradiation ) using bath water containing 0,5 mg/L of 8-methoxypsoralen ( 8-MOP ) . In 11 of the 12 patients , the skin lesions showed a significant improvement or even complete remission within six weeks of treatment . In one patient , only limited clinical improvement could be achieved . A mean of 19,1 ( SD +/- 3,6 ) PUVA-bath treatments were carried out . The mean cumulative UVA-dose given until clearance of the lichen planus was 16,7 ( SD +/- 4,8 ) J/cm2. No side effects were seen except an increased phototoxic reaction in two patients manifested as slight erythema . The results of this trial show , that PUVA-bath photochemotherapy with 8-MOP is an effective therapeutic alternative to all other known therapies in the treatment of extensive , exanthematic and also hypertrophic-hyperkeratotic lichen planus . In comparison to oral PUVA therapy and PUVA-bath therapy using 4,5 ' , 8-trimethoxypsoralen , balneophotochemotherapy with 8-MOP shows an excellent efficiency-side effect correlation . The clearance of the refractive skin lesions by balneophotochemotherapy with 8-MOP demonstrates the superiority of this therapy over all other common therapeutic modalities used for lichen planus ." ], "offsets": [ [ 0, 1401 ] ] } ]
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DerHautarzt.70480328.eng.abstr
DerHautarzt.70480328.eng.abstr
[ { "id": "DerHautarzt.70480328.eng.abstr-passage-0", "type": "abstract", "text": [ "Two young female patients presented with recurrent erythema and Henoch-Schoenlein purpura respectively . In both cases clinical , histological and radiological showed relatively mild , but previously undiagnosed Crohn's disease as a trigger . We describe the treatment of the underlying disease and the symptomatic treatment of skin lesions . Categories of specific and unspecific skin lesions associated with Crohn's disease , as described in the literature , are presented . Vasculitic changes of the deep versus the superficial dermal plexus are discussed ." ], "offsets": [ [ 0, 560 ] ] } ]
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[]
[]
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DerHautarzt.70480332.eng.abstr
DerHautarzt.70480332.eng.abstr
[ { "id": "DerHautarzt.70480332.eng.abstr-passage-0", "type": "abstract", "text": [ "Systemic vasculitides are potentially life-threatening diseases . Early and appropriate diagnosis based on case history , clinicopathological features , and laboratory parameters , such as the presence of anti-neutrophil cytoplasmic antibodies ( ANCA ) , is crucial for starting appropriate and , often , life-saving therapeutic measures . We report a 50-year-old female patient who presented with fever , arthralgias and hemoptysis . Skin signs included disseminated hemorrhagic pustules , ulcerations of oral and genital mucosa , subcutaneous nodules on arms and legs , and a pyoderma gangrenosum-like lesion on the right leg . Laboratory investigations revealed a peripheral eosinophilia and a positive cANCA titer . Histopathologic analysis of various biopsy specimens showed a granulomatous vasculitis in the subcutis , a nongranulomatous vasculitis with massive eosinophil infiltration in the lungs , and a segmental , necrotizing glomerulonephritis in the kidneys . Differential diagnosis included Wegener's granulomatosis , microscopic polyangiitis ( MPA ) and Churg-Strauss syndrome . MPA was diagnosed based on clinical and histopathological criteria . An interesting feature of this case was marked peripheral and tissue eosinophilia . Therapy consisted of cyclophosphamide and methylprednisolone . The patient went into a long-lasting clinical remission one month after starting therapy ." ], "offsets": [ [ 0, 1400 ] ] } ]
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[]
[]
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DerHautarzt.70480339.eng.abstr
DerHautarzt.70480339.eng.abstr
[ { "id": "DerHautarzt.70480339.eng.abstr-passage-0", "type": "abstract", "text": [ "Fractionated irradiation with X-rays or megavoltage is an important therapeutic option in the palliative treatment of Kaposi's sarcoma . We report on three HIV patients demonstrating bullous cutaneous eruptions in the irradiation field . Three homosexual men ( age 45-60 y ) stage of disease CDC 3C , were treated with fractionated soft X-rays with the scheme conventionally used by us ( total dose 30 Gy , single doses 3 Gy ) . Immediately to three days after completion of treatment large blisters appeared within the irradiation field , resolving after 2-4 weeks , leaving postinflammatory hyperpigmentation . The cause of this rare reaction to soft X-ray therapy , potentially suggesting an individually altered radiation sensitivity , is so far unknown . Controlled prospective studies applying different fractionation schemes will be necessary to better elucidate this issue ." ], "offsets": [ [ 0, 882 ] ] } ]
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DerHautarzt.70480343.eng.abstr
DerHautarzt.70480343.eng.abstr
[ { "id": "DerHautarzt.70480343.eng.abstr-passage-0", "type": "abstract", "text": [ "Two patients aged 50 and 84 years presented with generalized itching eczema that has been treated with external and internal steroids for months . Despite therapy , the condition worsened continuously . Examination of skin scrapings revealed numerous mites , so Norwegian scabies was diagnosed . General examinations excluded underlying diseases . Treatment with steroids over months most likely led via immunosuppression to the exacerbation of the disease ." ], "offsets": [ [ 0, 458 ] ] } ]
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[]
[]
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DerHautarzt.70480379.eng.abstr
DerHautarzt.70480379.eng.abstr
[ { "id": "DerHautarzt.70480379.eng.abstr-passage-0", "type": "abstract", "text": [ "Adjuvant basic therapy plays a central role in the therapeutic approach to atopic eczema in childhood . It involves the regular use of emollients and oil baths according to the clinical picture . Emollients containing urea may cause problems when used in younger children due to their stinging effect . Glucocorticosteroids still form the mainstay of anti-inflammatory therapy and are superior to other topical drugs with anti-inflammatory effects . Antihistamines preferably of the sedative type can be used successfully during periods of exacerbation . Systemic use of antibiotics is essential in cases of impetiginized atopic eczema . In cases of bacterial-triggered eczema , the topical use of antibiotics in cases of limited or of antiseptics in generalized disease may be helpful ." ], "offsets": [ [ 0, 787 ] ] } ]
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"DerHautarzt.70480379.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "atopic eczema" ], "offsets": [ [ 75, 88 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011615" } ] }, { "id": "DerHautarzt.70480379.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "use" ], "offsets": [ [ 128, 131 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042153" } ] }, { "id": "DerHautarzt.70480379.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "emollients" ], "offsets": [ [ 135, 145 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013983" } ] }, { "id": "DerHautarzt.70480379.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "oil" ], "offsets": [ [ 150, 153 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0028908" } ] }, { "id": "DerHautarzt.70480379.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "baths" ], "offsets": [ [ 154, 159 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0150141" } ] }, { "id": "DerHautarzt.70480379.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "Emollients" 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DerHautarzt.70480384.eng.abstr
DerHautarzt.70480384.eng.abstr
[ { "id": "DerHautarzt.70480384.eng.abstr-passage-0", "type": "abstract", "text": [ "In 33 patients with chronic venous incompetence ( CVI ) caused by primary varicoses or postthrombotic syndrome stage I-III ( according to Widmer ) the therapeutic benefit of 6 months of medically supervised physical exercise training was documented . During the training penud there was an improvement in subjective complains such as pain and tendency for edema in the legs . Mobility in the upper ankle joint was improved asuss as venous drainage function . Clinical benefit was achieved in the reduction of ulcer size ; 7 of 10 ulcers completely healed . Medically supervised physical exercise training and optimized compression therapy are basic therapeutic approaches in conservative treatment in chronic venous insufficiency . Costs are covered by the patient's health insurance company in Germany , as long as the exercise training is medically supervised ." ], "offsets": [ [ 0, 863 ] ] } ]
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DerHautarzt.70480391.eng.abstr
DerHautarzt.70480391.eng.abstr
[ { "id": "DerHautarzt.70480391.eng.abstr-passage-0", "type": "abstract", "text": [ "Numerous epidemiological studies on risk factors of malignant melanoma confirm the etiologic role of excessive UV-exposure especially in childhood . Preventive educational campaigns directed to parents of pre-school children have been inaugurated in several countries . In Germany the information was distributed by the \" Working group for Preventive Measures in Dermatology \" in cooperation with different public health institutions and the media starting in 1993. To evaluate the influence of these efforts on the knowledge and behaviour of the parents , two successive cross-sectional studies at all 56 nursery schools using the same standardised questionnaire were performed . The first interview took place in spring 1993 ( before the campaign ) with 1341 evaluable questionnaires ' , the second in fall 1994 ( after the campaign ) with 1150 evaluable questionnaires . The knowledge of the parents on melanoma risk factors was significantly improved in the second interview . Also the parental behavior regarding sun-protective measures when their children were outdoor at the beach or in the garden definitely changed . In 1993 the best textile sun protection was used by 21% of the parents at the beach and 36% in the garden . These numbers rose to 34% ( beach ) and 57% ( garden ) by the second interview . The percentage of children with no sunburn recorded during the preceding summer rose from 39% to 51% . According to the child's gender the parental behavior was different between the sexes ; boys were always better protected than girls . The design of this study with two cross-sectional surveys in the same population does not provide a methodologically sound basis for attributing the observed positive changes to the campaign . Without any doubt it can be stated that the parental knowledge and their attention to sun protection in their children showed substantial improvement in the second survey after the campaign . Thus , these results provide some evidence for the success of the preventive activities and confirm the necessity to continue with such activities ." ], "offsets": [ [ 0, 2086 ] ] } ]
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DerHautarzt.70480402.eng.abstr
DerHautarzt.70480402.eng.abstr
[ { "id": "DerHautarzt.70480402.eng.abstr-passage-0", "type": "abstract", "text": [ "13 patients with pyogenic granuloma were treated with a CO2 laser using the continuous wave laser in all cases and using additionally the ultrapulsed laser in 7 patients . The pyogenic granuloma was removed in all patients in one session . Side effects included transient erythema in 8 patients and scars in 2 cases . There was no hypo- or hyperpigmentation ." ], "offsets": [ [ 0, 359 ] ] } ]
[ { "id": "DerHautarzt.70480402.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 3, 11 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480402.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "granuloma" ], "offsets": [ [ 26, 35 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018188" } ] }, { "id": "DerHautarzt.70480402.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "CO2" ], "offsets": [ [ 56, 59 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007012" } ] }, { "id": "DerHautarzt.70480402.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "laser" ], "offsets": [ [ 60, 65 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023089" } ] }, { "id": "DerHautarzt.70480402.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "laser" ], "offsets": [ [ 92, 97 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023089" } ] }, { "id": "DerHautarzt.70480402.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "laser" ], "offsets": [ [ 150, 155 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023089" } ] }, { "id": "DerHautarzt.70480402.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 161, 169 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480402.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "pyogenic granuloma" ], "offsets": [ [ 17, 35 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0085653" } ] }, { "id": "DerHautarzt.70480402.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "granuloma" ], "offsets": [ [ 185, 194 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018188" } ] }, { "id": "DerHautarzt.70480402.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 214, 222 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480402.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "pyogenic granuloma" ], "offsets": [ [ 176, 194 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0085653" } ] }, { "id": "DerHautarzt.70480402.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "transient" ], "offsets": [ [ 262, 271 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040704" } ] }, { "id": "DerHautarzt.70480402.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "erythema" ], "offsets": [ [ 272, 280 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0041834" } ] }, { "id": "DerHautarzt.70480402.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 286, 294 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480402.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "scars" ], "offsets": [ [ 299, 304 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008767" } ] }, { "id": "DerHautarzt.70480402.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "Side effects" ], "offsets": [ [ 240, 252 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001688" } ] }, { "id": "DerHautarzt.70480402.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "hyperpigmentation" ], "offsets": [ [ 340, 357 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162834" } ] } ]
[]
[]
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"id": "DerHautarzt.70480402.eng.abstr-s1-r11-t3.1-t2.1", "type": "affects", "arg1_id": "DerHautarzt.70480402.eng.abstr-s3-t3", "arg2_id": "DerHautarzt.70480402.eng.abstr-s3-t2", "normalized": [] }, { "id": "DerHautarzt.70480402.eng.abstr-s1-r12-t8.1-t3.1", "type": "produces", "arg1_id": "DerHautarzt.70480402.eng.abstr-s1-t8", "arg2_id": "DerHautarzt.70480402.eng.abstr-s3-t3", "normalized": [] }, { "id": "DerHautarzt.70480402.eng.abstr-s1-r13-t8.1-t2.1", "type": "degree_of", "arg1_id": "DerHautarzt.70480402.eng.abstr-s1-t8", "arg2_id": "DerHautarzt.70480402.eng.abstr-s3-t2", "normalized": [] }, { "id": "DerHautarzt.70480402.eng.abstr-s1-r14-t4.1-t8.1", "type": "causes", "arg1_id": "DerHautarzt.70480402.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.70480402.eng.abstr-s1-t8", "normalized": [] }, { "id": "DerHautarzt.70480402.eng.abstr-s1-r15-t4.1-t2.1", "type": "causes", "arg1_id": "DerHautarzt.70480402.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.70480402.eng.abstr-s3-t2", "normalized": [] }, { "id": "DerHautarzt.70480402.eng.abstr-s1-r16-t5.1-t8.1", "type": "causes", "arg1_id": "DerHautarzt.70480402.eng.abstr-s3-t5", "arg2_id": "DerHautarzt.70480402.eng.abstr-s1-t8", "normalized": [] }, { "id": "DerHautarzt.70480402.eng.abstr-s1-r17-t3.1-t8.1", "type": "affects", "arg1_id": "DerHautarzt.70480402.eng.abstr-s3-t3", "arg2_id": "DerHautarzt.70480402.eng.abstr-s1-t8", "normalized": [] }, { "id": "DerHautarzt.70480402.eng.abstr-s1-r18-t1.1-t6.1", "type": "uses", "arg1_id": "DerHautarzt.70480402.eng.abstr-s4-t1", "arg2_id": "DerHautarzt.70480402.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerHautarzt.70480402.eng.abstr-s1-r19-t7.1-t6.1", "type": "uses", "arg1_id": "DerHautarzt.70480402.eng.abstr-s1-t7", "arg2_id": "DerHautarzt.70480402.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerHautarzt.70480402.eng.abstr-s1-r20-t5.1-t2.1", "type": "causes", "arg1_id": "DerHautarzt.70480402.eng.abstr-s3-t5", "arg2_id": "DerHautarzt.70480402.eng.abstr-s3-t2", "normalized": [] }, { "id": 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"DerHautarzt.70480402.eng.abstr-s4-t1", "arg2_id": "DerHautarzt.70480402.eng.abstr-s3-t4", "normalized": [] }, { "id": "DerHautarzt.70480402.eng.abstr-s3-r20-t4.1-t5.1", "type": "location_of", "arg1_id": "DerHautarzt.70480402.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.70480402.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerHautarzt.70480402.eng.abstr-s3-r21-t1.1-t4.1", "type": "result_of", "arg1_id": "DerHautarzt.70480402.eng.abstr-s4-t1", "arg2_id": "DerHautarzt.70480402.eng.abstr-s3-t4", "normalized": [] }, { "id": "DerHautarzt.70480402.eng.abstr-s3-r22-t1.1-t4.1", "type": "co-occurs_with", "arg1_id": "DerHautarzt.70480402.eng.abstr-s4-t1", "arg2_id": "DerHautarzt.70480402.eng.abstr-s3-t4", "normalized": [] } ]
DerHautarzt.70480406.eng.abstr
DerHautarzt.70480406.eng.abstr
[ { "id": "DerHautarzt.70480406.eng.abstr-passage-0", "type": "abstract", "text": [ "We report the first case of prurigo pigmentosa in the German literature . For over a year , a 16-year old white girl developed an immensely pruritic symmetrical reticular , papulo-vesicular eruption on the trunk , axillae and pubic region . Histologically a superficial perivascular spongiotic and lichenoid inflammatory pattern with prominent pigmentary incontinence in older lesions was observed . Topical corticosteroids and systemic antihistamines had no effect . Systemic corticosteroids and diaminophenylsulphone ( DADPS ) produced improvement but could not prevent recurrences . Healing occurred only after 4 weeks of systemic- minocycline ." ], "offsets": [ [ 0, 648 ] ] } ]
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[]
[]
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DerHautarzt.70480410.eng.abstr
DerHautarzt.70480410.eng.abstr
[ { "id": "DerHautarzt.70480410.eng.abstr-passage-0", "type": "abstract", "text": [ "A 35 year old patient developed swellings in the red colored areas of his tattoo . Histological examination revealed a lichenoid , pseudolymphomatous infiltrative pattern , that could be distinguished from frank lymphoma by means of electron microscopy , immunohistochemistry and molecular biology . The presence of dermal dendritic cells suggests a dermal-allergic pathogenesis of non-granulomatous tattoo reactions . Therapy of choice is an excision of the inflamed areas ." ], "offsets": [ [ 0, 475 ] ] } ]
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[]
[]
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DerHautarzt.70480414.eng.abstr
DerHautarzt.70480414.eng.abstr
[ { "id": "DerHautarzt.70480414.eng.abstr-passage-0", "type": "abstract", "text": [ "Solitary or bilateral , symptomless exostoses on the lingual surface of the mandibule are called mandibular torus . It is mainly seen in young males and has a benign clinical course . The etiopathology is not known . Both genetic and environmental factors such as the anatomy of the lower jaw are considered . Syndromes associated with facial exostoses such as Proteus syndrome or Gardner's syndrome should be clinically excluded . A 40-year-old man with exostoses of the jaw is reported . With this case report we would like to draw attention to a disease which has rarely been described in the German dermatological literature ." ], "offsets": [ [ 0, 630 ] ] } ]
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[]
[]
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"DerHautarzt.70480414.eng.abstr-s6-r10-t3.1-t2.2", "type": "location_of", "arg1_id": "DerHautarzt.70480414.eng.abstr-s7-t3", "arg2_id": "DerHautarzt.70480414.eng.abstr-s6-t2", "normalized": [] }, { "id": "DerHautarzt.70480414.eng.abstr-s7-r1-t1.1-t2.1", "type": "result_of", "arg1_id": "DerHautarzt.70480414.eng.abstr-s7-t1", "arg2_id": "DerHautarzt.70480414.eng.abstr-s7-t2", "normalized": [] }, { "id": "DerHautarzt.70480414.eng.abstr-s7-r2-t2.1-t1.1", "type": "result_of", "arg1_id": "DerHautarzt.70480414.eng.abstr-s7-t2", "arg2_id": "DerHautarzt.70480414.eng.abstr-s7-t1", "normalized": [] } ]
DerHautarzt.70480417.eng.abstr
DerHautarzt.70480417.eng.abstr
[ { "id": "DerHautarzt.70480417.eng.abstr-passage-0", "type": "abstract", "text": [ "In hair germ tumors , hair follicle development is partially or completely recapitulated . The trichoblastoma represents a purely epithelial tumour within this group of tumours . We identified a trichoblastoma showing exclusively adenocystic features in a 32 years old woman . This variant has been very rarely described in the literature . We review the history of hair germ tumors and discuss the problems of their classification ." ], "offsets": [ [ 0, 433 ] ] } ]
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[]
[]
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DerHautarzt.70480425.eng.abstr
DerHautarzt.70480425.eng.abstr
[ { "id": "DerHautarzt.70480425.eng.abstr-passage-0", "type": "abstract", "text": [ "The dermatological clinic in Zwickau celebrated 50 years of existence in 1996. We review the clinics history , starting with its founding in 1946 because of the upsurge in venerological diseases during the post-world war II years . The most important clinic directory and their scientific activities are described ." ], "offsets": [ [ 0, 315 ] ] } ]
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[]
[]
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DerHautarzt.70480455.eng.abstr
DerHautarzt.70480455.eng.abstr
[ { "id": "DerHautarzt.70480455.eng.abstr-passage-0", "type": "abstract", "text": [ "The different methods that are available for the assessment and quantification of \" brittle nails \" and for the evaluation of various therapeutical approaches are compared . At this time , measurement of the swelling properties is the best documented and most reliable method for studying the treatment of brittle nails . Reliable qualitative data can also be obtained by scanning electron microscopy . Measurement of the transonychial water loss and assessment of thickness and density of nails by ultrasound have also been used successfully , but the methodology still has to be improved and the reproducibility , confirmed ." ], "offsets": [ [ 0, 627 ] ] } ]
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[]
[]
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"normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s2-r2-t2.1-t1.1", "type": "measures", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t2", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s2-r3-t2.1-t4.1", "type": "conceptual_part_of", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t2", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t4", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s2-r4-t2.1-t3.2", "type": "measures", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t2", "arg2_id": "DerHautarzt.70480455.eng.abstr-s2-t3", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s3-r1-t4.1-t1.1", "type": "measures", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t4", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s3-r2-t2.1-t1.1", "type": "measures", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t2", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s3-r3-t3.1-t1.1", "type": "measures", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t3", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s4-r1-t5.1-t2.2", "type": "analyzes", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t5", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t2", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s4-r2-t1.1-t4.1", "type": "measures", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t1", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t4", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s4-r3-t1.1-t5.3", "type": "measures", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t1", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t5", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s4-r4-t5.1-t1.1", "type": "precedes", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t5", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s4-r5-t3.1-t1.1", "type": "measures", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t3", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s4-r6-t1.1-t2.2", "type": "measures", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t1", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t2", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s4-r7-t6.1-t3.1", "type": "conceptual_part_of", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t6", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t3", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s4-r8-t3.1-t5.3", "type": "measures", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t3", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t5", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s4-r9-t6.1-t5.1", "type": "conceptual_part_of", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t6", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t5", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s4-r10-t5.1-t1.1", "type": "measures", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t5", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s4-r11-t3.1-t4.1", "type": "analyzes", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t3", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t4", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s4-r13-t3.1-t2.2", "type": "analyzes", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t3", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t2", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s4-r14-t5.1-t4.1", "type": "analyzes", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t5", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t4", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s4-r15-t3.1-t1.1", "type": "precedes", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t3", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t1", "normalized": [] }, { "id": "DerHautarzt.70480455.eng.abstr-s4-r16-t2.2-t5.3", "type": "affects", "arg1_id": "DerHautarzt.70480455.eng.abstr-s4-t2", "arg2_id": "DerHautarzt.70480455.eng.abstr-s4-t5", "normalized": [] } ]
DerHautarzt.70480462.eng.abstr
DerHautarzt.70480462.eng.abstr
[ { "id": "DerHautarzt.70480462.eng.abstr-passage-0", "type": "abstract", "text": [ "The Q-switched ruby laser ( QSRL ) with its wavelength of 694 nm and a pulse duration of around 40 nsec is an effective modality for the removal of tattoos and cutaneous pigmented lesions . Based on the principle of selective photothermolysis , selective damage to cutaneous pigment or pigmented cells is possible , allowing the scar-free elimination of endogenous or exogenous pigment in the skin . Main indications for the treatment with the QSRL are tattoos ( amateur , professional , accidental , or cosmetic ) and lentigines but the QSRL can also be used for lightening or even removing other pigmented lesions such as nevus spilus or café au lait macules . Furthermore , pigmented lesions of mucous membranes can be removed easily . Since treatment results in postinflammatory hyperpigmentation , melasma , and Becker ' nevus have proven to be inconsistent , the QSRL cannot be routinely recommended for these lesions . Melanocytic lesions are generally not treated , with the exception of nevus of Ota and nevus of Ito where there exacts a lack of therapeutic alternatives . Non-pigmented cells , which exist in nearly all melanocytic lesions , do not absorb the light of the QSRL and , therefore , do not react to this particular treatment . No information is available on the risk of partially damaged cells to become malignant after QSRL treatment . The QSRL is an excellent therapy for the removal of endogenous and exogenous pigment because of both the excellent treatment results and the lack of side effects , which are limited to transient hypo- and hyperpigmentation . The QSRL has accurred a wide range of applications within the field of dermatology ." ], "offsets": [ [ 0, 1669 ] ] } ]
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"normalized": [ { "db_name": "UMLS", "db_id": "C0023321" } ] }, { "id": "DerHautarzt.70480462.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "nevus" ], "offsets": [ [ 624, 629 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027960" } ] }, { "id": "DerHautarzt.70480462.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "mucous" ], "offsets": [ [ 698, 704 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026727" } ] }, { "id": "DerHautarzt.70480462.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "membranes" ], "offsets": [ [ 705, 714 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025255" } ] }, { "id": "DerHautarzt.70480462.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "mucous membranes" ], "offsets": [ [ 698, 714 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026724" } ] }, { "id": "DerHautarzt.70480462.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 745, 754 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerHautarzt.70480462.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "hyperpigmentation" ], "offsets": [ [ 783, 800 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162834" } ] }, { "id": "DerHautarzt.70480462.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "melasma" ], "offsets": [ [ 803, 810 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025218" } ] }, { "id": "DerHautarzt.70480462.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "nevus" ], "offsets": [ [ 826, 831 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027960" } ] }, { "id": "DerHautarzt.70480462.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "proven" ], "offsets": [ [ 837, 843 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0700164" } ] }, { "id": "DerHautarzt.70480462.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "nevus" ], "offsets": [ [ 996, 1001 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027960" } ] }, { "id": "DerHautarzt.70480462.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "nevus" ], "offsets": [ [ 1013, 1018 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027960" } ] }, { "id": "DerHautarzt.70480462.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "therapeutic" ], "offsets": [ [ 1055, 1066 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039796" } ] }, { "id": "DerHautarzt.70480462.eng.abstr-s6-t4", "type": "umlsterm", "text": [ "nevus of Ota" ], "offsets": [ [ 996, 1008 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027961" } ] }, { "id": "DerHautarzt.70480462.eng.abstr-s6-t5", "type": "umlsterm", "text": [ "nevus of Ito" ], "offsets": [ [ 1013, 1025 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022283" } ] }, { "id": "DerHautarzt.70480462.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 1096, 1101 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerHautarzt.70480462.eng.abstr-s7-t2", "type": "umlsterm", 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[]
[]
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DerHautarzt.70480471.eng.abstr
DerHautarzt.70480471.eng.abstr
[ { "id": "DerHautarzt.70480471.eng.abstr-passage-0", "type": "abstract", "text": [ "The well-documented positive effect of compression stocking therapy on the venous macro- and microhemodynamics of the legs can only be attained if the stockings fit well . In order to determine the effective pressure exerted by compression stockings , we usually deleted in US journals . One can get this out of journal and author's address have developed a new measuring method based on piezoresistant microprobes and a microprocessor unit . With our 2-mm-thick, 5-mm diameter probe , the pressure between the compression stocking and skin can be measured at any location desired . A temporal resolution of 50 Hz makes it possible to carry out dynamic measurements while the patient is walking or performing exercises on tiptoes . Here we present 4 typical cases out of a total of over 80 which we have evaluated . We have decided empirically that the pressure exerted by a class-2 compression stocking on the skin at the height of the ankles ( b-position ) should not exceed 70 mm Hg while resting and a peak of 110 mm Hg while exercising on tiptoes . At the middle of the calf ( c-position ) these values should not exceed 60 mm Hg at rest and 80 mm Hg on tiptoes . The pressure should decrease from the distal to proximal direction in order to produce a drainage gradient . We have found empirically that a pressure gradient of 30-40% from the b to the c measurement is favorable . Too high a proximal pressure or too high a pressure on a part of the lower leg causes pain and swelling . Too low a pressure , on the other hand , does not produce the desired vascular effect and alleviation of symptoms . Although dynamic pressure measurements take about 20-30 minutes per leg , they markedly improve patient compliance with compression therapy ." ], "offsets": [ [ 0, 1749 ] ] } ]
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[]
[]
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DerHautarzt.70480482.eng.abstr
DerHautarzt.70480482.eng.abstr
[ { "id": "DerHautarzt.70480482.eng.abstr-passage-0", "type": "abstract", "text": [ "Sarcoidosis is characterised by the formation of sarcoidal granulomas in all affected organs . Despite intensive research , the cause of the disease in unknown . There are only a few reports suggesting an induction of sarcoidosis by interferons . Three patients are presented in whom sarcoidosis developed during or after interferon alpha therapy . The probability of interferon therapy as cause of sarcoidosis is discussed ." ], "offsets": [ [ 0, 425 ] ] } ]
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[]
[]
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DerHautarzt.70480488.eng.abstr
DerHautarzt.70480488.eng.abstr
[ { "id": "DerHautarzt.70480488.eng.abstr-passage-0", "type": "abstract", "text": [ "A 66-year-old woman with longstanding lichen sclerosus et atrophicus improved strikingly with PUVA bath photochemotherapy over a period of 6 weeks . The cumulative UVA dose was 31.7 J/cm2; the single UVA dose ranged from 0.3 to 2.3 J/cm2. After 16 treatment sessions , the sclerotic lesions had softened greatly , while after 24 treatments , the skin lesions were almost completely cleared and pruritus was diminished . Histopathological analysis of biopsy specimens from previously affected sites as well as 20 MHz ultrasound examinations showed almost no residual sclerosis ." ], "offsets": [ [ 0, 577 ] ] } ]
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[]
[]
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DerHautarzt.70480492.eng.abstr
DerHautarzt.70480492.eng.abstr
[ { "id": "DerHautarzt.70480492.eng.abstr-passage-0", "type": "abstract", "text": [ "A 35 year-old male suffered from an extremely painful embolia cutis medicamentosa . The atypical segmental localization first led to the diagnosis of herpes zoster and an antiviral therapy . Regarding the unusual course of the complication following an intramuscular injection in this case , the question for the real pathomechanisms still remains ." ], "offsets": [ [ 0, 349 ] ] } ]
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[]
[]
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DerHautarzt.70480496.eng.abstr
DerHautarzt.70480496.eng.abstr
[ { "id": "DerHautarzt.70480496.eng.abstr-passage-0", "type": "abstract", "text": [ "A 65 year old male patient was diagnosed with hereditary hemorrhagic telangiectasia at 30. During recent years he has suffered frequent , almost daily , nose bleeds causing anemia and making several blood transfusions necessary . In the past 2-3 years , the patient has developed multiple squamous cell carcinomas on the face . These ununsually large tumours were treated by micrographic surgery using paraffin sections and the defects closed with a variety of flaps and grafts . Several solar keratoses were also removed . If hemostasis parameters are normal , skin surgery can be performed without hestitation in hereditary hemorrhagic telangiectasia ." ], "offsets": [ [ 0, 654 ] ] } ]
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"DerHautarzt.70480496.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "anemia" ], "offsets": [ [ 173, 179 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002871" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "blood" ], "offsets": [ [ 199, 204 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005767" }, { "db_name": "UMLS", "db_id": "C0005768" }, { "db_name": "UMLS", "db_id": "C0005835" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "nose bleeds" ], "offsets": [ [ 153, 164 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014591" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "blood transfusions" ], "offsets": [ [ 199, 217 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005841" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s1-t10", "type": "umlsterm", "text": [ "hereditary hemorrhagic telangiectasia" ], "offsets": [ [ 46, 83 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039445" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 258, 265 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 298, 302 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "carcinomas" ], "offsets": [ [ 303, 313 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "face" ], "offsets": [ [ 321, 325 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015450" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "squamous cell carcinomas" ], "offsets": [ [ 289, 313 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007137" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "tumours" ], "offsets": [ [ 351, 358 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027651" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 388, 395 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "paraffin" ], "offsets": [ [ 402, 410 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030415" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "defects" ], "offsets": [ [ 428, 435 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243067" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "flaps" ], "offsets": [ [ 461, 466 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038925" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "grafts" ], "offsets": [ [ 471, 477 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0332835" }, { "db_name": "UMLS", "db_id": "C0040733" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "keratoses" ], "offsets": [ [ 494, 503 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022593" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "hemostasis" ], "offsets": [ [ 527, 537 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019116" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 562, 566 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 567, 574 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "hestitation" ], "offsets": [ [ 600, 611 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022023" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "telangiectasia" ], "offsets": [ [ 638, 652 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039446" } ] }, { "id": "DerHautarzt.70480496.eng.abstr-s5-t6", "type": "umlsterm", "text": [ "hereditary hemorrhagic telangiectasia" ], "offsets": [ [ 615, 652 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039445" } ] } ]
[]
[]
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DerHautarzt.70480523.eng.abstr
DerHautarzt.70480523.eng.abstr
[ { "id": "DerHautarzt.70480523.eng.abstr-passage-0", "type": "abstract", "text": [ "The invisible long-wave ultraviolet radiation ( 340-450 nm , max . 365 nm ) produced by a Wood lamp can help to diagnose dermatoses with a characteristic fluorescence ( tinea capitis , erythrasma , tinea versicolor , Pseudomonas infections , porphyrians , and pigmentary alterations ) . It is also used in the detection of medications that are taken systemcally ( tetracycline ) or that are applied to the skin . Recently , a fluorescence technique with Wood light has been used as a preventive measure to monitor and quantify skin protection at the workplace and to teach workers in high-risk occupations the proper use of protective creams ." ], "offsets": [ [ 0, 643 ] ] } ]
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"umlsterm", "text": [ "tinea" ], "offsets": [ [ 169, 174 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040247" } ] }, { "id": "DerHautarzt.70480523.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "erythrasma" ], "offsets": [ [ 185, 195 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014752" } ] }, { "id": "DerHautarzt.70480523.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "tinea" ], "offsets": [ [ 198, 203 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040247" } ] }, { "id": "DerHautarzt.70480523.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "Pseudomonas" ], "offsets": [ [ 217, 228 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033808" } ] }, { "id": "DerHautarzt.70480523.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "infections" ], "offsets": [ [ 229, 239 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021311" } ] }, { "id": "DerHautarzt.70480523.eng.abstr-s2-t9", "type": "umlsterm", "text": [ "tinea capitis" ], "offsets": [ [ 169, 182 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040250" } ] }, { "id": "DerHautarzt.70480523.eng.abstr-s2-t10", "type": "umlsterm", "text": [ "tinea versicolor" ], "offsets": [ [ 198, 214 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040262" } ] }, { "id": "DerHautarzt.70480523.eng.abstr-s2-t11", "type": "umlsterm", "text": [ "Pseudomonas infections" ], "offsets": [ [ 217, 239 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033817" } ] }, { "id": "DerHautarzt.70480523.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "medications" ], "offsets": [ [ 323, 334 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013227" } ] }, { "id": "DerHautarzt.70480523.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "tetracycline" ], "offsets": [ [ 364, 376 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039651" }, { "db_name": "UMLS", "db_id": "C0039644" } ] }, { "id": "DerHautarzt.70480523.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 406, 410 ] ], 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"DerHautarzt.70480523.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "measure" ], "offsets": [ [ 495, 502 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079809" } ] }, { "id": "DerHautarzt.70480523.eng.abstr-s4-t7", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 527, 531 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.70480523.eng.abstr-s4-t8", "type": "umlsterm", "text": [ "workplace" ], "offsets": [ [ 550, 559 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162579" } ] }, { "id": "DerHautarzt.70480523.eng.abstr-s4-t9", "type": "umlsterm", "text": [ "workers" ], "offsets": [ [ 573, 580 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024752" } ] }, { "id": "DerHautarzt.70480523.eng.abstr-s4-t10", "type": "umlsterm", "text": [ "occupations" ], "offsets": [ [ 594, 605 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0028811" } ] }, { "id": "DerHautarzt.70480523.eng.abstr-s4-t11", "type": "umlsterm", "text": [ "use" 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[]
[]
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DerHautarzt.70480528.eng.abstr
DerHautarzt.70480528.eng.abstr
[ { "id": "DerHautarzt.70480528.eng.abstr-passage-0", "type": "abstract", "text": [ "The role of allergic reactions in eliciting and maintaining atopic eczema ( AE ) is still controversial . In a subgroup of patients with atopic eczema , exacerbations of itching and eczematous skin lesions have been described after contact with aeroallergens . To investigate this observation , an epicutaneous patch test with IgE-inducing allergens ( atopy patch test , APT ) has been proposed , which results in eczematous skin reactions in 30-70% of AE patients . Usage of allergen concentrations exceeding 5000 PNU/g in petrolatum allows testing on clinically uninvolved skin without potentially irritating epidermal tape stripping . The clinical relevance of positive APT reactions is suggested by comparison of APT with skin prick test , specific IgE , patient's history and eczema pattern . Patients with an eczema pattern with preferred localization of skin lesions in air-exposed areas , a predictive history and raised specific IgE ( depending on allergen ) were shown to have the highest rate of positive APT . Future controlled studies with allergen avoidance and re-exposition may focus on this patient group ." ], "offsets": [ [ 0, 1123 ] ] } ]
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DerHautarzt.70480536.eng.abstr
DerHautarzt.70480536.eng.abstr
[ { "id": "DerHautarzt.70480536.eng.abstr-passage-0", "type": "abstract", "text": [ "The pulsed dye laser ( wavelength 585 nm , pulse duration 0,3-0,45 ms ) is very effective in the treatment of port-wine stains , beginning hemangiomas , telangiectasias , spider nevi , xanthelasma and red hypertrophic scarring . It is the laser of choice in the therapy of young patients with port-wine stains . The pulsed dye laser is limited by its relatively superficial penetration into the skin with a maximum of 1,5 mm ." ], "offsets": [ [ 0, 426 ] ] } ]
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[]
[]
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DerHautarzt.70480541.eng.abstr
DerHautarzt.70480541.eng.abstr
[ { "id": "DerHautarzt.70480541.eng.abstr-passage-0", "type": "abstract", "text": [ "Adverse reactions to seafood are common and may cause many types of symptoms that are difficult to define . The nature of these reactions are variable including allergic and toxic reactions as well as infectious diseases . The differentiation between these entities is essential in choosing therapy . We describe 9 patients with IgE mediated allergic reactions due to crustaceans and fish diagnosed from case history , clinical findings , skin tests and specific IgE antibodies . Most symptoms of a IgE mediated allergic reaction appear within 30 minutes after ingestion . Characteristic clinical features may include an urticarial rash , gastrointestinal symptoms and even anaphylaxis . In this case immediate therapy with intravenous glucocorticoids , antihistamine and perhaps subcutaneous epinephrine is required ." ], "offsets": [ [ 0, 818 ] ] } ]
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[]
[]
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DerHautarzt.70480547.eng.abstr
DerHautarzt.70480547.eng.abstr
[ { "id": "DerHautarzt.70480547.eng.abstr-passage-0", "type": "abstract", "text": [ "We analyzed how psoriasis patients sought professional help and correlated it to their illness attitudes and feelings of stigmatization . Semi-structured interviews of 400 patients were reanalyzed to identify homogeneous groups concerning initial reactions at first manifestations of the disease . Four groups ( \" isolated \" , \" stigmatized \" , \" socially supported \" and \" non-stigmatized \" patients ) were found and cross-tabulated with five resulting groups of a second cluster-analysis concerning the \" style \" of the seeking behaviour of professional and paraprofessional help and medical measures against the psoriasis ( \" multi-users \" , \" arranged mini-users \" , \" waiting-room patients \" , \" optimists \" and \" self- therapists \" ) . We were able to describe typical courses of illness behaviour depending on the initial reaction . The results are discussed with regard to the desirable identification of problematic patients within professional care units ." ], "offsets": [ [ 0, 966 ] ] } ]
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[]
[]
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DerHautarzt.70480568.eng.abstr
DerHautarzt.70480568.eng.abstr
[ { "id": "DerHautarzt.70480568.eng.abstr-passage-0", "type": "abstract", "text": [ "Three patients presented with an acquired green discoloration of their scalp hair . History revealed that all of them swam regularly in private swimming pools . Examination of the hair by atomic emission spectroscopy showed that the green discoloration was caused by an excessively high copper content of the hair . This exogeneous discoloration is characteristically related to the uptake of copper from private swimming pools ." ], "offsets": [ [ 0, 429 ] ] } ]
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[]
[]
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DerHautarzt.70480572.eng.abstr
DerHautarzt.70480572.eng.abstr
[ { "id": "DerHautarzt.70480572.eng.abstr-passage-0", "type": "abstract", "text": [ "In the literature , a number of observers reported that acrokeratosis verruciformis ( Hopf ) often evolves in cases of keratosis follicularis . The relationship of these verruciform manifestations to keratosis follicularis is discussed . In this paper , we present three patients with Darier's disease , who have verruciform papules on the dorsal surfaces of the hands and feet . Histopathologically , the papules showed the distinctive structures of Darier's disease . Therefore , these lesions are regarded as an abortive form of keratosis follicularis . It is necessary to examine carefully the punch biopsies histomorphologically . We also recommend having a closer look at the development of other typical Darier's skin lesions in the follow-up of patients ." ], "offsets": [ [ 0, 763 ] ] } ]
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[]
[]
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DerHautarzt.70480577.eng.abstr
DerHautarzt.70480577.eng.abstr
[ { "id": "DerHautarzt.70480577.eng.abstr-passage-0", "type": "abstract", "text": [ "Patient with extensive keratosis palmoplantaris maculosa seu papulosa ( Davies-Colley ) presented with multiple cutaneous horns . The clinical picture , the histology , the electro microscopic examination , the negative tumor screening and the viral classification in the tissue allowed the differentiation from other palmoplantar keratoses . The patient was treated successfully using a combination of acitretin with physical and chemical measures ." ], "offsets": [ [ 0, 450 ] ] } ]
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[]
[]
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DerHautarzt.70480615.eng.abstr
DerHautarzt.70480615.eng.abstr
[ { "id": "DerHautarzt.70480615.eng.abstr-passage-0", "type": "abstract", "text": [ "Telomerase is an enzyme that elongates telomeric repeats , the specialized structures at the ends of chromosomes that provide genomic stability and compensate for the physiologic process of telomere shortening . It has been implicated in cellular senescence , immortalization , and carcinogenesis . Over 85% of human tumours , and 95% of non-melanocytic skin cancers , show telomerase activity , in contrast to the corresponding normal tissues . This suggests that telomerase activity may play an important role in carcinogenesis . Recent evidence shows that telomerase is active not only in embryonal and germ line tissues , but also in some normal tissues . In the skin , this activity has been traced to the stem-cell-bearing epidermal basal cell layer , possibly reflecting the presence of telomerase-competent stem cells . These findings require a reconsideration of our interpretation of telomerase activity in tumours of the skin and other tissues . As a causal relationship linking telomerase activity and cancer has yet not been demonstrated , some caution is warranted ." ], "offsets": [ [ 0, 1080 ] ] } ]
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"cancers" ], "offsets": [ [ 359, 366 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006826" } ] }, { "id": "DerHautarzt.70480615.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "telomerase" ], "offsets": [ [ 374, 384 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087071" } ] }, { "id": "DerHautarzt.70480615.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "contrast" ], "offsets": [ [ 399, 407 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0110625" } ] }, { "id": "DerHautarzt.70480615.eng.abstr-s3-t7", "type": "umlsterm", "text": [ "tissues" ], "offsets": [ [ 436, 443 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "DerHautarzt.70480615.eng.abstr-s3-t8", "type": "umlsterm", "text": [ "skin cancers" ], "offsets": [ [ 354, 366 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007114" } ] }, { "id": "DerHautarzt.70480615.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "telomerase" ], "offsets": [ [ 465, 475 ] ], "normalized": [ { 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"DerHautarzt.70480615.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "germ line" ], "offsets": [ [ 606, 615 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017473" } ] }, { "id": "DerHautarzt.70480615.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 667, 671 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.70480615.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 745, 749 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerHautarzt.70480615.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "telomerase-competent" ], "offsets": [ [ 794, 814 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087071" } ] }, { "id": "DerHautarzt.70480615.eng.abstr-s6-t4", "type": "umlsterm", "text": [ "stem" ], "offsets": [ [ 815, 819 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162731" } ] }, { "id": "DerHautarzt.70480615.eng.abstr-s6-t5", "type": "umlsterm", "text": [ 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[]
[]
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DerHautarzt.70480622.eng.abstr
DerHautarzt.70480622.eng.abstr
[ { "id": "DerHautarzt.70480622.eng.abstr-passage-0", "type": "abstract", "text": [ "Vascular malformations and neoplasms are very common skin disorders , found in up to 5% of newborns . However , a clear distinction has to be made between proliferating vascular lesions and permanent malformations . An exact classification is also extremely useful , since many new specific diagnostic and therapeutic measures have been developed in recent years . True proliferating tumors are , for example , childhood hemangiomas , glomus tumors , granuloma pyogenicum , tufted angiomas , senile angiomas , and malignant vascular lesions . Vascular malformations can affect capillaries , veins or arteries , as well as lymphatic vessels . Arteriovenous shunts and combined malformations may also exist ( Hamburg classification ) . Nevi flammei , nevi anaemici , hematolymphangiomas , angiokeratotic nevi , circumscribed venous-arterious malformations , and the blue-rubber-bleb-nevus-syndrome may either be infiltrating or circumscribed and are characterised by a persistence of the primitive vessel network . In contrast , other malformations involve various vascular trunks , showing vessel dilatation or obstruction , often combined with changes in bone or soft tissue . Significant large vessel malformations are the Bockenheimer syndrome , the Klippel-Trenaunay syndrome and the Parkes-Weber syndrome . Combinations involving both large trunks and extravascular space such as the Klippel-Trenaunay syndrome also occur ." ], "offsets": [ [ 0, 1427 ] ] } ]
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} ] }, { "id": "DerHautarzt.70480622.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "skin disorders" ], "offsets": [ [ 53, 67 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037274" } ] }, { "id": "DerHautarzt.70480622.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "malformations" ], "offsets": [ [ 200, 213 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0000768" }, { "db_name": "UMLS", "db_id": "C0243070" } ] }, { "id": "DerHautarzt.70480622.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "exact" ], "offsets": [ [ 219, 224 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0059927" } ] }, { "id": "DerHautarzt.70480622.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "classification" ], "offsets": [ [ 225, 239 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008902" }, { "db_name": "UMLS", "db_id": "C0008903" } ] }, { "id": "DerHautarzt.70480622.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "diagnostic" ], "offsets": [ [ 291, 301 ] ], "normalized": [ { "db_name": 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[]
[]
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"DerHautarzt.70480622.eng.abstr-s9-r1-t1.1-t6.1", "type": "location_of", "arg1_id": "DerHautarzt.70480622.eng.abstr-s10-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t6", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r2-t1.1-t1.2", "type": "produces", "arg1_id": "DerHautarzt.70480622.eng.abstr-s10-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t1", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r3-t1.2-t2.2", "type": "affects", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t2", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r4-t1.2-t6.1", "type": "affects", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t6", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r5-t1.1-t4.1", "type": "location_of", "arg1_id": "DerHautarzt.70480622.eng.abstr-s10-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t4", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r6-t1.2-t6.1", "type": "result_of", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t6", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r7-t1.2-t5.1", "type": "affects", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t5", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r8-t1.2-t4.1", "type": "affects", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t4", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r9-t1.2-t4.1", "type": "diagnoses", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t4", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r10-t1.2-t2.2", "type": "result_of", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t2", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r11-t1.2-t1.1", "type": "disrupts", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s10-t1", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r12-t1.1-t2.2", "type": "location_of", "arg1_id": "DerHautarzt.70480622.eng.abstr-s10-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t2", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r13-t1.2-t5.1", "type": "diagnoses", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t5", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r14-t2.2-t4.1", "type": "result_of", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t2", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t4", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r15-t1.1-t5.1", "type": "location_of", "arg1_id": "DerHautarzt.70480622.eng.abstr-s10-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t5", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r16-t1.2-t6.1", "type": "diagnoses", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t6", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r17-t2.2-t5.1", "type": "result_of", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t2", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t5", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r18-t1.2-t4.1", "type": "result_of", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t4", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r19-t1.2-t2.2", "type": "causes", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t2", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r20-t1.2-t2.2", "type": "diagnoses", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t2", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r21-t2.2-t6.1", "type": "result_of", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t2", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t6", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r22-t1.1-t1.2", "type": "location_of", "arg1_id": "DerHautarzt.70480622.eng.abstr-s10-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t1", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r23-t1.2-t5.1", "type": "result_of", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t5", "normalized": [] }, { "id": "DerHautarzt.70480622.eng.abstr-s9-r24-t1.2-t2.2", "type": "treats", "arg1_id": "DerHautarzt.70480622.eng.abstr-s9-t1", "arg2_id": "DerHautarzt.70480622.eng.abstr-s9-t2", "normalized": [] } ]
DerHautarzt.70480629.eng.abstr
DerHautarzt.70480629.eng.abstr
[ { "id": "DerHautarzt.70480629.eng.abstr-passage-0", "type": "abstract", "text": [ "Fifty-three patients with psoriasis , 24 patients with atopic eczema and 52 controls with healthy skin were compared with regard to their sexual behavior . For the test , questionnaires developed by Arentewicz as well as our own questionnaire on sexuality and partnership were used . Patients with skin diseases had a significantly impaired sex life , compared to those with healthy skin . There was a highly significant reduction in the exchange of tenderness in patients of both sexes , and in the capacity for orgasm in female patients . On the other hand , no significant difference was found concerning the frequency of intercourse . Patients with psoriasis felt more impaired than those with atopic eczema . Ninety-three percent of psoriatics and 96% of patients with atopic eczema had not been asked about their sexual life by their attending doctor . We discuss to what extent skin diseases are possibly involved in the regulation of nearness and distance among partners . The dermatologist should a be knowledgeable and understanding source for patients which skin diseases who have questions about their disease and its effect on their sex life ." ], "offsets": [ [ 0, 1156 ] ] } ]
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], "offsets": [ [ 98, 102 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "behavior" ], "offsets": [ [ 145, 153 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004927" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "atopic eczema" ], "offsets": [ [ 55, 68 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011615" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "test" ], "offsets": [ [ 164, 168 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0076174" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "questionnaires" ], "offsets": [ [ 171, 185 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034394" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "questionnaire" ], "offsets": [ [ 229, 242 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034394" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "sexuality" ], "offsets": [ [ 246, 255 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036915" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "Patients" ], "offsets": [ [ 284, 292 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 298, 302 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "diseases" ], "offsets": [ [ 303, 311 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "sex" ], "offsets": [ [ 341, 344 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079399" }, { "db_name": "UMLS", "db_id": "C0009253" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "life" ], "offsets": [ [ 345, 349 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376558" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 383, 387 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s3-t7", "type": "umlsterm", "text": [ "skin diseases" ], "offsets": [ [ 298, 311 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037274" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 464, 472 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "sexes" ], "offsets": [ [ 481, 486 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079399" }, { "db_name": "UMLS", "db_id": "C0009253" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "orgasm" ], "offsets": [ [ 513, 519 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029260" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "female" ], "offsets": [ [ 523, 529 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0086287" }, { "db_name": "UMLS", "db_id": "C0015780" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 530, 538 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "hand" ], "offsets": [ [ 554, 558 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018563" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "frequency" ], "offsets": [ [ 612, 621 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376249" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "intercourse" ], "offsets": [ [ 625, 636 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009253" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "Patients" ], "offsets": [ [ 639, 647 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "psoriasis" ], "offsets": [ [ 653, 662 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033860" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "eczema" ], "offsets": [ [ 705, 711 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013595" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s6-t4", "type": "umlsterm", "text": [ "atopic eczema" ], "offsets": [ [ 698, 711 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011615" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 760, 768 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "eczema" ], "offsets": [ [ 781, 787 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013595" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s7-t3", "type": "umlsterm", "text": [ "life" ], "offsets": [ [ 826, 830 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376558" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s7-t4", "type": "umlsterm", "text": [ "doctor" ], "offsets": [ [ 850, 856 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031831" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s7-t5", "type": "umlsterm", "text": [ "atopic eczema" ], "offsets": [ [ 774, 787 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011615" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 885, 889 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s8-t2", "type": "umlsterm", "text": [ "diseases" ], "offsets": [ [ 890, 898 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s8-t3", "type": "umlsterm", "text": [ "regulation" ], "offsets": [ [ 928, 938 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034982" }, { "db_name": "UMLS", "db_id": "C0220905" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s8-t4", "type": "umlsterm", "text": [ "distance" ], "offsets": [ [ 955, 963 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012751" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s8-t5", "type": "umlsterm", "text": [ "skin diseases" ], "offsets": [ [ 885, 898 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037274" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s9-t1", "type": "umlsterm", "text": [ "understanding" ], "offsets": [ [ 1029, 1042 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162340" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s9-t2", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 1054, 1062 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s9-t3", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 1069, 1073 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s9-t4", "type": "umlsterm", "text": [ "diseases" ], "offsets": [ [ 1074, 1082 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s9-t5", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 1114, 1121 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerHautarzt.70480629.eng.abstr-s9-t6", "type": "umlsterm", "text": [ "sex" ], "offsets": [ [ 1146, 1149 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079399" }, { "db_name": "UMLS", "db_id": "C0009253" } ] }, { "id": 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[]
[]
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DerHautarzt.70480634.eng.abstr
DerHautarzt.70480634.eng.abstr
[ { "id": "DerHautarzt.70480634.eng.abstr-passage-0", "type": "abstract", "text": [ "Recurrent phlebothromboses in young patients with subsequent severe postthrombotic syndrome and chronic venous leg ulcers may be caused by underlying hereditary disorders of hemostasis or may occur as part of other congenital syndromes . The most common hereditary disorders of hemostasis in this respect appear to be deficiencies of antithrombin III , protein C , and protein S , and activated protein C resistance ( mutations of factor V ) . Less frequently , dysfibrinogenemia , increased plasminogen activator inhibitor levels , or deficiencies of tissue plasminogen activator or heparin cofactor II may be found . Klinefelter's syndrome and homocystinuria are prime examples of those rare congenital disorders indirectly associated with an elevated risk of thrombosis in young individuals . Early diagnosis of these disorders will allow timely treatment , preventive care and counselling of patients as well as family members ." ], "offsets": [ [ 0, 932 ] ] } ]
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DerHautarzt.70480640.eng.abstr
DerHautarzt.70480640.eng.abstr
[ { "id": "DerHautarzt.70480640.eng.abstr-passage-0", "type": "abstract", "text": [ "Bart syndrome was described first by Bart in 1966 ; it represents the combination of congenital epidermolysis bullosa , congenital localized absence of skin affecting the extremities and shedding or dystrophy of nails . This syndrome may be of clinical relevance because of its more favourable prognosis in comparison with other forms of epidermolysis bullosa . We report two patients with Bart syndrome and focus on the question , if this syndrome represents a distinct entity or a variant of epidermolysis bullosa ." ], "offsets": [ [ 0, 517 ] ] } ]
[ { "id": "DerHautarzt.70480640.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "syndrome" ], "offsets": [ [ 5, 13 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039082" } ] }, { "id": "DerHautarzt.70480640.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "congenital" ], "offsets": [ [ 85, 95 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009678" } ] }, { "id": "DerHautarzt.70480640.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "congenital" ], "offsets": [ [ 120, 130 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009678" } ] }, { "id": "DerHautarzt.70480640.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 152, 156 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.70480640.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "extremities" ], "offsets": [ [ 171, 182 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015385" } ] }, { "id": "DerHautarzt.70480640.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "nails" ], "offsets": [ [ 212, 217 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027342" } ] }, { "id": "DerHautarzt.70480640.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "epidermolysis bullosa" ], "offsets": [ [ 96, 117 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014527" } ] }, { "id": "DerHautarzt.70480640.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "syndrome" ], "offsets": [ [ 225, 233 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039082" } ] }, { "id": "DerHautarzt.70480640.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "prognosis" ], "offsets": [ [ 294, 303 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033325" } ] }, { "id": "DerHautarzt.70480640.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "forms" ], "offsets": [ [ 329, 334 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376315" } ] }, { "id": "DerHautarzt.70480640.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "epidermolysis bullosa" ], "offsets": [ [ 338, 359 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014527" } ] }, { "id": "DerHautarzt.70480640.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 376, 384 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480640.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "syndrome" ], "offsets": [ [ 395, 403 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039082" } ] }, { "id": "DerHautarzt.70480640.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "syndrome" ], "offsets": [ [ 440, 448 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039082" } ] }, { "id": "DerHautarzt.70480640.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "epidermolysis bullosa" ], "offsets": [ [ 494, 515 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014527" } ] } ]
[]
[]
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"normalized": [] }, { "id": "DerHautarzt.70480640.eng.abstr-s3-r3-t2.1-t1.1", "type": "occurs_in", "arg1_id": "DerHautarzt.70480640.eng.abstr-s3-t2", "arg2_id": "DerHautarzt.70480640.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerHautarzt.70480640.eng.abstr-s3-r4-t3.1-t1.1", "type": "occurs_in", "arg1_id": "DerHautarzt.70480640.eng.abstr-s3-t3", "arg2_id": "DerHautarzt.70480640.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerHautarzt.70480640.eng.abstr-s3-r5-t4.1-t1.1", "type": "occurs_in", "arg1_id": "DerHautarzt.70480640.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.70480640.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerHautarzt.70480640.eng.abstr-s3-r6-t4.1-t3.1", "type": "result_of", "arg1_id": "DerHautarzt.70480640.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.70480640.eng.abstr-s3-t3", "normalized": [] }, { "id": "DerHautarzt.70480640.eng.abstr-s3-r7-t4.1-t2.1", "type": "result_of", "arg1_id": "DerHautarzt.70480640.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.70480640.eng.abstr-s3-t2", "normalized": [] } ]
DerHautarzt.70480645.eng.abstr
DerHautarzt.70480645.eng.abstr
[ { "id": "DerHautarzt.70480645.eng.abstr-passage-0", "type": "abstract", "text": [ "Of 46 patients with severe atopic eczema treated with UVA-1, 14 were evaluated as non-responders and 32 as responders . Responding patients significantly had ( p 0.05 ) more severe skin involvement before onset of treatment ( clinical severity score SCORAD 62.7 +/- 12.4 points ) compared to non-responders ( 53.0 +/- 10.6 points ) . Serum levels of total IgE , ECP and sIL2R before treatment did not show any significant differences between the two groups . The data confirm the efficacy of UVA-1 treatment in severe cases of atopic eczema ." ], "offsets": [ [ 0, 542 ] ] } ]
[ { "id": "DerHautarzt.70480645.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 6, 14 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480645.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "eczema" ], "offsets": [ [ 34, 40 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013595" } ] }, { "id": "DerHautarzt.70480645.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "atopic eczema" ], "offsets": [ [ 27, 40 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011615" } ] }, { "id": "DerHautarzt.70480645.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 131, 139 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480645.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 181, 185 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.70480645.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 214, 223 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerHautarzt.70480645.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "IgE" ], "offsets": [ [ 356, 359 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020846" } ] }, { "id": "DerHautarzt.70480645.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 383, 392 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerHautarzt.70480645.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 498, 507 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerHautarzt.70480645.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "eczema" ], "offsets": [ [ 534, 540 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013595" } ] }, { "id": "DerHautarzt.70480645.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "atopic eczema" ], "offsets": [ [ 527, 540 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011615" } ] } ]
[]
[]
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DerHautarzt.70480653.eng.abstr
DerHautarzt.70480653.eng.abstr
[ { "id": "DerHautarzt.70480653.eng.abstr-passage-0", "type": "abstract", "text": [ "The association of nevus flammeus with mongolian spot , nevus fuscoceruleus , nevus spilus and , with variable frequency , with nevus anemicus has been termed phacomatosis pigmentovascularis , a genodermatosis first described by Ota and co-workers . Four different combinations have been specified . Most cases are reported from the Japanese literature . Phacomatosis pigmentovascularis may constitute an exclusively cutaneous disorder , but overlapping with other syndromes like Klippel-Trenaunay syndrome or Sturge-Weber syndrome is also possible . We report a 30-year-old woman with nevus flammeus on the back and right arm associated with nevus fuscoceruleus on the back ." ], "offsets": [ [ 0, 676 ] ] } ]
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"DerHautarzt.70480653.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "nevus" ], "offsets": [ [ 78, 83 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027960" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "frequency" ], "offsets": [ [ 111, 120 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376249" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "nevus" ], "offsets": [ [ 128, 133 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027960" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "phacomatosis" ], "offsets": [ [ 159, 171 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0041341" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s1-t10", "type": "umlsterm", "text": [ "co-workers" ], "offsets": [ [ 237, 247 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024752" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s1-t11", "type": "umlsterm", "text": [ "nevus flammeus" ], "offsets": [ [ 19, 33 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0235752" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "literature" ], "offsets": [ [ 342, 352 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023866" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "Phacomatosis" ], "offsets": [ [ 355, 367 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0265316" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "disorder" ], "offsets": [ [ 427, 435 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "syndromes" ], "offsets": [ [ 465, 474 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039082" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "syndrome" ], "offsets": [ [ 498, 506 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039082" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "syndrome" ], "offsets": [ [ 523, 531 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039082" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "Klippel-Trenaunay syndrome" ], "offsets": [ [ 480, 506 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022739" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s4-t7", "type": "umlsterm", "text": [ "Sturge-Weber syndrome" ], "offsets": [ [ 510, 531 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038505" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "woman" ], "offsets": [ [ 575, 580 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043210" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "nevus" ], "offsets": [ [ 586, 591 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027960" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "back" ], "offsets": [ [ 608, 612 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004600" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "right" ], "offsets": [ [ 617, 622 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035621" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "arm" ], "offsets": [ [ 623, 626 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003792" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s5-t6", "type": "umlsterm", "text": [ "nevus" ], "offsets": [ [ 643, 648 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027960" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s5-t7", "type": "umlsterm", "text": [ "back" ], "offsets": [ [ 670, 674 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004600" } ] }, { "id": "DerHautarzt.70480653.eng.abstr-s5-t8", "type": "umlsterm", "text": [ "nevus flammeus" ], "offsets": [ [ 586, 600 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0235752" } ] } ]
[]
[]
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DerHautarzt.70480657.eng.abstr
DerHautarzt.70480657.eng.abstr
[ { "id": "DerHautarzt.70480657.eng.abstr-passage-0", "type": "abstract", "text": [ "A 19-year old caucasian patient suffered from ulceration and scaring of his fingers since age two . During childhood , fibrosing contractures on the phalanges developed . Since puberty , his eunuch-like stature , bird-like face and exophthalmos had become under obvious . His hair was extraordinarily fine ; his pubic hair rare . Radiological examination revealed ankylosis and osteoporosis of the phalanges and carpals . Angiography showed occlusion of multiple digital and interdigital arteries . Furthermore , a bilateral posterior cataract , restrictive respiratory disease , impaired glucose tolerance , hyperuricemia , proteinuria and primary hypogonadism were diagnosed . These findings are characteristic for the premature aging syndromes . The cardial symptoms of tall stature , bird-like face , pseudoexophthalmos , skleroderma-like and poikiloderma-like cutaneous lesions , scarce hair growth , early diabetes mellitus and arteriosclerosis led to the diagnosis of metageria ." ], "offsets": [ [ 0, 986 ] ] } ]
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"normalized": [ { "db_name": "UMLS", "db_id": "C0018494" } ] }, { "id": "DerHautarzt.70480657.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "hair" ], "offsets": [ [ 318, 322 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018494" } ] }, { "id": "DerHautarzt.70480657.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "ankylosis" ], "offsets": [ [ 364, 373 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003090" } ] }, { "id": "DerHautarzt.70480657.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "osteoporosis" ], "offsets": [ [ 378, 390 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0029456" } ] }, { "id": "DerHautarzt.70480657.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "carpals" ], "offsets": [ [ 412, 419 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007285" } ] }, { "id": "DerHautarzt.70480657.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "Angiography" ], "offsets": [ [ 422, 433 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002978" } ] }, { "id": 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"proteinuria" ], "offsets": [ [ 625, 636 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033687" } ] }, { "id": "DerHautarzt.70480657.eng.abstr-s7-t6", "type": "umlsterm", "text": [ "hypogonadism" ], "offsets": [ [ 649, 661 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020619" } ] }, { "id": "DerHautarzt.70480657.eng.abstr-s7-t7", "type": "umlsterm", "text": [ "respiratory disease" ], "offsets": [ [ 558, 577 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035242" } ] }, { "id": "DerHautarzt.70480657.eng.abstr-s7-t8", "type": "umlsterm", "text": [ "primary hypogonadism" ], "offsets": [ [ 641, 661 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022735" } ] }, { "id": "DerHautarzt.70480657.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "findings" ], "offsets": [ [ 685, 693 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243095" } ] }, { "id": "DerHautarzt.70480657.eng.abstr-s8-t2", "type": "umlsterm", "text": [ "syndromes" ], "offsets": [ [ 737, 746 ] ], 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"id": "DerHautarzt.70480657.eng.abstr-s9-t5", "type": "umlsterm", "text": [ "growth" ], "offsets": [ [ 897, 903 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018270" }, { "db_name": "UMLS", "db_id": "C0220844" } ] }, { "id": "DerHautarzt.70480657.eng.abstr-s9-t6", "type": "umlsterm", "text": [ "diabetes" ], "offsets": [ [ 912, 920 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011847" }, { "db_name": "UMLS", "db_id": "C0011849" } ] }, { "id": "DerHautarzt.70480657.eng.abstr-s9-t7", "type": "umlsterm", "text": [ "arteriosclerosis" ], "offsets": [ [ 934, 950 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003850" } ] }, { "id": "DerHautarzt.70480657.eng.abstr-s9-t8", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 962, 971 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] } ]
[]
[]
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DerHautarzt.70480666.eng.abstr
DerHautarzt.70480666.eng.abstr
[ { "id": "DerHautarzt.70480666.eng.abstr-passage-0", "type": "abstract", "text": [ "Allergic reactions in tattoos are comparatively rare . In most cases the reactions are caused by different red pigments . While in the past these reactions have been ascribed to mercury salts ( cinnebar ) and cadmium sulphide , now synthetic inorganic azo dyes have also been found to be responsible for such reactions . A 42-year-old man presented with an allergic reaction in the red parts of his tattoos . Histologically a chronic granulomatous , partly fibrous inflammation with transfollicular elimination of pigment granules was found . Spontaneous regression in a part of the inflammatory reaction was observed , simultaneously with depigmentation and scarring of the overlying skin . The pigment used for tattooing was found to be an aromatic azo derivative . In addition to a positive cutaneous reaction to the dye , the patient also showed a positive patch test to Napthol AS , used for the coupling of different dyes in the textile industry ." ], "offsets": [ [ 0, 953 ] ] } ]
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"text": [ "cadmium" ], "offsets": [ [ 209, 216 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006632" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "sulphide" ], "offsets": [ [ 217, 225 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038739" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "dyes" ], "offsets": [ [ 256, 260 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013343" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "cadmium sulphide" ], "offsets": [ [ 209, 225 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0054417" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "man" ], "offsets": [ [ 335, 338 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025266" }, { "db_name": "UMLS", "db_id": "C0024554" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "tattoos" ], "offsets": [ [ 399, 406 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039343" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "allergic reaction" ], "offsets": [ [ 357, 374 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0085600" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "inflammation" ], "offsets": [ [ 465, 477 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021368" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "pigment" ], "offsets": [ [ 514, 521 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031916" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "granules" ], "offsets": [ [ 522, 530 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0010837" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "regression" ], "offsets": [ [ 555, 565 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034979" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 685, 689 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "inflammatory reaction" ], "offsets": [ [ 583, 604 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021368" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "pigment" ], "offsets": [ [ 696, 703 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031916" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "derivative" ], "offsets": [ [ 755, 765 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243072" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "dye" ], "offsets": [ [ 820, 823 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013343" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s8-t2", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 830, 837 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s8-t3", "type": "umlsterm", "text": [ "test" ], "offsets": [ [ 867, 871 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0076174" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s8-t4", "type": "umlsterm", "text": [ "dyes" ], "offsets": [ [ 923, 927 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013343" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s8-t5", "type": "umlsterm", "text": [ "textile" ], "offsets": [ [ 935, 942 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039717" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s8-t6", "type": "umlsterm", "text": [ "industry" ], "offsets": [ [ 943, 951 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021267" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s8-t7", "type": "umlsterm", "text": [ "patch test" ], "offsets": [ [ 861, 871 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030646" } ] }, { "id": "DerHautarzt.70480666.eng.abstr-s8-t8", "type": "umlsterm", "text": [ "textile industry" ], "offsets": [ [ 935, 951 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039716" } ] } ]
[]
[]
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DerHautarzt.70480707.eng.abstr
DerHautarzt.70480707.eng.abstr
[ { "id": "DerHautarzt.70480707.eng.abstr-passage-0", "type": "abstract", "text": [ "Co-existing inflammation and epidermal hyperproliferation characteristic for psoriasis have been shown to be reproducible in several animal models utilizing a variety of different strategies . These models highlight some points of the multicausal pathogenesis of psoriasis . Based on observations made in the animal models , a hypothesis is proposed for the pathogenesis of psoriasis , the elements of which can be tested in a recently established xenogeneic transplantation model ." ], "offsets": [ [ 0, 482 ] ] } ]
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[]
[]
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"measures", "arg1_id": "DerHautarzt.70480707.eng.abstr-s3-t1", "arg2_id": "DerHautarzt.70480707.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerHautarzt.70480707.eng.abstr-s3-r16-t1.1-t3.1", "type": "associated_with", "arg1_id": "DerHautarzt.70480707.eng.abstr-s3-t1", "arg2_id": "DerHautarzt.70480707.eng.abstr-s3-t3", "normalized": [] }, { "id": "DerHautarzt.70480707.eng.abstr-s3-r17-t6.2-t3.1", "type": "associated_with", "arg1_id": "DerHautarzt.70480707.eng.abstr-s3-t6", "arg2_id": "DerHautarzt.70480707.eng.abstr-s3-t3", "normalized": [] } ]
DerHautarzt.70480714.eng.abstr
DerHautarzt.70480714.eng.abstr
[ { "id": "DerHautarzt.70480714.eng.abstr-passage-0", "type": "abstract", "text": [ "Different flea species may infest humans temporarily . Such arthropods should be considered as a possible cause of erythematous and pruritic papules and nodules of unclear origin . Bites from animal fleas can be seen in people with close contact to domestic or wild animals . This dermatosis may often be misdiagnosed . Several flea species including Pulex irritans , Ctenocephalides canis , Ctenocephalides felis , Ceratophyllus gallinae , Ceratophyllus columbae and Archaeopsylla erinacei may infest human skin , causing symptoms . Flea bite-allergy and the role of various flea species as disease vectors are also discussed ." ], "offsets": [ [ 0, 628 ] ] } ]
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[]
[]
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DerHautarzt.70480720.eng.abstr
DerHautarzt.70480720.eng.abstr
[ { "id": "DerHautarzt.70480720.eng.abstr-passage-0", "type": "abstract", "text": [ "The evaluation of melanocytic tumors represents one of the most intriguing and challenging aspects of the daily practice in dermatohistopathology . For the diagnosis of malignant melanoma and melanocytic nevi , standardized and reproducible criteria are required . In case of the diagnosis of melanoma , the histopathological report must include all important data relevant for the prognosis which may also influence the therapeutic procedure . The following paper summarizes the recommendations of the study group on malignant melanoma formed by the Deutsche Dermatologische Gesellschaft ." ], "offsets": [ [ 0, 590 ] ] } ]
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[]
[]
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DerHautarzt.70480730.eng.abstr
DerHautarzt.70480730.eng.abstr
[ { "id": "DerHautarzt.70480730.eng.abstr-passage-0", "type": "abstract", "text": [ "In dermatological practice , itch is the leading symptom of many skin diseases with a variety of psychophysiological aspects . However , a complete inventory for the qualitative evaluation of these central nervous factors is missing , whereas in pain research , the McGill Pain Questionnaire is well established for this purpose . Thus , therapeutic effects of antipruritic agents are only incompletely described by visual analog scales or parameters of skin physiology . Here , a questionnaire modified in analogy to the McGill pain questionnaire is presented , developed in cooperation between dermatologists and neurophysiologists ." ], "offsets": [ [ 0, 635 ] ] } ]
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DerHautarzt.70480734.eng.abstr
DerHautarzt.70480734.eng.abstr
[ { "id": "DerHautarzt.70480734.eng.abstr-passage-0", "type": "abstract", "text": [ "In Germany , insect allergies cause about 10-40 death per year . Starting a specific immunotherapy ( SIT ) and its maintenance may be lifesaving for the allergic patients . Performing a prospective study , we exactly documented effects and side effects during the induction phase of SIT using a purified aqueous yellow jacket venom preparation in 20 patients allergic to yellow jacket venom ( clinical degree II-IV ) . Indication for the therapy was defined individually for each patient and was based on a score incorporating the following criteria : a ) clinical symptoms , b ) in-vivo- and in-vitro testing , c ) risk of re-sting . SIT was started under inpatient conditions following a standardized 8 day protocol . At the end of the induction phase all patients tolerated the maintenance dose of 100 µg of yellow jacket venom without complications even though all showed local side effects ( threshold doses 0.01-10 µg, median value 0.2 µg). 40% of all patients showed subjective side effects ( median value of threshold dose 30 µg, range 0.2-60 µg) and 30% showed objective side effects ( median value of threshold dose 55 µg, range 20-80 µg); however , all side effects were clinically mild . When objective systemic side effects were seen , the cumulative daily dose was 39-210 µg ( median value 135 µg), exceeding 100 µg in 83% of patients . Our prospective study confirmed that the chosen protocol for SIT is effective in inducing tolerance to the venom preparation . However , using a purified aqueous yellow jacket preparation did not result in reduction of side effects ." ], "offsets": [ [ 0, 1584 ] ] } ]
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[]
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"normalized": [] } ]
DerHautarzt.70480740.eng.abstr
DerHautarzt.70480740.eng.abstr
[ { "id": "DerHautarzt.70480740.eng.abstr-passage-0", "type": "abstract", "text": [ "A 39-year old male developed multiple verrucous papules on his back following a severe sunburn . Both the clinical features and pathology were typical for disseminated epidermolytic acanthomas . These benign skin lesions resemble the papules of Darier's disease , seborrhoic keratoses or verrucae planae . The light-exposed skin of the back is the site of predilection . Electron microscopy reveals a premature and altered cornification of keratinocytes . Epidermolytic acanthomas are acquired , harmless lesions and must be differentiated from more serious , congenital ichthyoses of the skin , showing the same histopathologic picture ." ], "offsets": [ [ 0, 638 ] ] } ]
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[]
[]
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DerHautarzt.70480749.eng.abstr
DerHautarzt.70480749.eng.abstr
[ { "id": "DerHautarzt.70480749.eng.abstr-passage-0", "type": "abstract", "text": [ "Two cases of foreign body granulomas developed after correction of face wrinkles with Bioplastique - a new microimplant . The characteristic histopathologic findings of a foreign body granuloma with cystic spaces and bizarre outlined , glassy material led to the correct diagnosis ' Bioplastique-granuloma' in spite of scarce clinical information ." ], "offsets": [ [ 0, 348 ] ] } ]
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[]
[]
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DerHautarzt.70480759.eng.abstr
DerHautarzt.70480759.eng.abstr
[ { "id": "DerHautarzt.70480759.eng.abstr-passage-0", "type": "abstract", "text": [ "Nuchal fibroma is a fibrolipoma-like soft tissue mass , located on the back and neck of middle-aged men . Clinically it presents as adiffuse indurated subcutaneous swelling and , sometimes painful and inflamed . Since the first descriptions , by Enzinger and Weiss and Lister et al. both in 1988 , under the name \" collagenosis nuchae \" , only 15 additional cases have been reported . Nonetheless , the lesion is comparatively common . We report another case of nuchal fibroma enphaszing the distinctive clinical and histopathological features of this lesion and its differential diagnosis ." ], "offsets": [ [ 0, 591 ] ] } ]
[ { "id": "DerHautarzt.70480759.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "fibroma" ], "offsets": [ [ 7, 14 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016045" } ] }, { "id": "DerHautarzt.70480759.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "tissue" ], "offsets": [ [ 42, 48 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0040300" } ] }, { "id": "DerHautarzt.70480759.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "back" ], "offsets": [ [ 71, 75 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004600" } ] }, { "id": "DerHautarzt.70480759.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "neck" ], "offsets": [ [ 80, 84 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027530" } ] }, { "id": "DerHautarzt.70480759.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "men" ], "offsets": [ [ 100, 103 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025266" }, { "db_name": "UMLS", "db_id": "C0024554" } ] }, { "id": "DerHautarzt.70480759.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "name" ], "offsets": [ [ 308, 312 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027365" } ] }, { "id": "DerHautarzt.70480759.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "fibroma" ], "offsets": [ [ 469, 476 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016045" } ] }, { "id": "DerHautarzt.70480759.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "histopathological" ], "offsets": [ [ 517, 534 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243140" } ] }, { "id": "DerHautarzt.70480759.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 580, 589 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "DerHautarzt.70480759.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "differential diagnosis" ], "offsets": [ [ 567, 589 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220820" }, { "db_name": "UMLS", "db_id": "C0011906" } ] } ]
[]
[]
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DerHautarzt.70480762.eng.abstr
DerHautarzt.70480762.eng.abstr
[ { "id": "DerHautarzt.70480762.eng.abstr-passage-0", "type": "abstract", "text": [ "In 1837 , Germany's first in-patient dermatological department named \" Heilanstalt fuer Flechtenkranke \" was founded by Dr. Albert Friedrich Veiel in the city of Cannstatt ( which since 1905 is part of Stuttgart ) . Later his son , Dr. Theodor Veiel , directed this private dermatological clinic , and became head of the district hospital of Cannstatt in 1881. Although he was active in many areas of medicine , dermatology was his main interest . He very much influenced the development of dermatology during his period as president of the German Dermatology Association until his death in 1923. In 1935 , the first dermatological city hospital was established in Cannstatt/Stuttgart . But , after World War II , all the medical facilities were taken over by the US Army . Thus , medical activities including dermatology had to be spread all over Stuttgart , until in 1965 they were returned to their former place . At the end of 1998 , the large abandoned US army hospital will home a totally renovated and modernized Stuttgart dermatology hospital ." ], "offsets": [ [ 0, 1052 ] ] } ]
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[]
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DerHautarzt.70480787.eng.abstr
DerHautarzt.70480787.eng.abstr
[ { "id": "DerHautarzt.70480787.eng.abstr-passage-0", "type": "abstract", "text": [ "Epidural lipomatosis can be induced by systemic glucocorticoid treatment and may cause severe neurologic deficits . So far , 41 patients have been reported in the literature . Early recognition of this rare , relatively unknown , but extremely important side effect of exogenously administered glucocorticoids can help avoid persistent neurological sequeloe ." ], "offsets": [ [ 0, 359 ] ] } ]
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[]
[]
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DerHautarzt.70480791.eng.abstr
DerHautarzt.70480791.eng.abstr
[ { "id": "DerHautarzt.70480791.eng.abstr-passage-0", "type": "abstract", "text": [ "Nearly all drugs currently used during the course of general anaesthesia may lead to hypersensitivity reactions of various types . There may be an acute type I allergic reactions or to a more or less severe pseudoallergic reactions , in rare cases with lethal outcome . Routine preoperative testing appears of little predictive value , in spite of the high frequency of so-called risk factors ( atopy , other kind of allergy ) among the evaluated group of patients . Careful allergological testing should be performed 4 to 6 weeks after any incidents of suspected drug intolerance , in order to discover the underlying causative agent . Skin testing is of diagnostic value for neuromuscular blockers and intravenous narcotics . RAST- and RIA-tests and/or mediator releasing tests may also used additionally . Together with all other administered drugs , all the routinely used neuromuscular blockers ( suxamethonium , vecuronium , pancuronium , alcuronium , atracurium , mivacurium ) should be tested , since they often represent the cause for such reactions . For other classes of drugs ( for example , volatile anesthetics and opioids ) the clinical relevance of skin testing still remains uncertain . For less severe incidents seen during general anaesthesia such as pruritus , or exanthems , skin testing seems to be less relevant ." ], "offsets": [ [ 0, 1336 ] ] } ]
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DerHautarzt.70480800.eng.abstr
DerHautarzt.70480800.eng.abstr
[ { "id": "DerHautarzt.70480800.eng.abstr-passage-0", "type": "abstract", "text": [ "The Clarke-Howel-Evans-McConnell-Syndrome is a rare hereditary disease characterized by palmoplantar keratoses , squamous cell carcinoma of the esophagus and oral leukoplakia . According to a new classification recently proposed by Stevens and colleagues , the syndrome can also be classified as Palmoplantar Ectodermal Dysplasia Type III . We report a family from the Black Forest region of Germany afflicted with the syndrome . The family was traced through five generation . 27 of 46 family members showed tylotic skin changes . In addition , 8 patients showed oral leukoplakia and 5 died from squamous cell carcinoma of the esophagus . Using screening examinations , early changes of the esophageal mucosa could be detected . The responsible gene has been mapped in the family . It is located at 17q23-qter, telomeric to the keratin II gene cluster . Therefore a defect in one of the well known keratin genes can be excluded as a cause of the syndrome ." ], "offsets": [ [ 0, 957 ] ] } ]
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[]
[]
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DerHautarzt.70480806.eng.abstr
DerHautarzt.70480806.eng.abstr
[ { "id": "DerHautarzt.70480806.eng.abstr-passage-0", "type": "abstract", "text": [ "Compression therapy was employed for 4 weeks 20 patients with chronic venous insufficiency stage CVI I and CVI II according to Widmer's classification . Compression bandaging for 2 weeks was followed by compression stockings for 2 more weeks . The cutaneous microcirculation was evaluated before therapy , after 2 weeks and after finishing compression therapy after 4 weeks . Marked improvement in symptoms such as pain and itching was observed after 4 weeks , along with a significant reduction in lower limb volume . Video capillary microscopy revealed an increase in capillary density associated with a decrease in capillary diameter and pericapillary halo diameter . Compression treatment achieves at least part of its effect by improving the function of the skin microcirculation . The efficacy of bandaging and stockings was similar ." ], "offsets": [ [ 0, 840 ] ] } ]
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[]
[]
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"DerHautarzt.70480806.eng.abstr-s6-r13-t2.1-t1.1", "type": "affects", "arg1_id": "DerHautarzt.70480806.eng.abstr-s6-t2", "arg2_id": "DerHautarzt.70480806.eng.abstr-s6-t1", "normalized": [] } ]
DerHautarzt.70480812.eng.abstr
DerHautarzt.70480812.eng.abstr
[ { "id": "DerHautarzt.70480812.eng.abstr-passage-0", "type": "abstract", "text": [ "Between 1992 and 1994 two multicentre studies were performed in order to determine the frequency of sensitization to gold salts . In the first study ( 1992-1993 ) , 872 patients were tested with gold sodium thiosulfate ( NTS ) 0.25% in Vaseline ( V ) , 0.5% V. and with potassium dicyanoaurate ( KDC ) 0.002% aqueous solution . 44 patients ( 5.1% ) had a positive patch test reaction to gold salts : 40 ( 4.6% ) to NTS 0.5% V. , 20 ( 2.3% ) to NTS 0.25% V. and 5 ( 0.6% ) to KDC . A higher number of positive patch tests to gold salts was noted in patients also sensitized to another metal salt ( 8.5% ) as compared to those who showed no other sensitivities ( 3.6% ) ." ], "offsets": [ [ 0, 669 ] ] } ]
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"text": [ "gold" ], "offsets": [ [ 195, 199 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018026" } ] }, { "id": "DerHautarzt.70480812.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "sodium" ], "offsets": [ [ 200, 206 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037473" } ] }, { "id": "DerHautarzt.70480812.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "thiosulfate" ], "offsets": [ [ 207, 218 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039950" } ] }, { "id": "DerHautarzt.70480812.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "NTS" ], "offsets": [ [ 221, 224 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0175518" } ] }, { "id": "DerHautarzt.70480812.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "Vaseline" ], "offsets": [ [ 236, 244 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0728774" } ] }, { "id": "DerHautarzt.70480812.eng.abstr-s2-t7", "type": "umlsterm", "text": [ "potassium" ], "offsets": [ [ 270, 279 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0032821" } ] }, { "id": "DerHautarzt.70480812.eng.abstr-s2-t8", "type": "umlsterm", "text": [ "dicyanoaurate" ], "offsets": [ [ 280, 293 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0208063" } ] }, { "id": "DerHautarzt.70480812.eng.abstr-s2-t9", "type": "umlsterm", "text": [ "solution" ], "offsets": [ [ 317, 325 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037633" } ] }, { "id": "DerHautarzt.70480812.eng.abstr-s2-t10", "type": "umlsterm", "text": [ "sodium thiosulfate" ], "offsets": [ [ 200, 218 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0074774" } ] }, { "id": "DerHautarzt.70480812.eng.abstr-s2-t11", "type": "umlsterm", "text": [ "gold sodium thiosulfate" ], "offsets": [ [ 195, 218 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037512" } ] }, { "id": "DerHautarzt.70480812.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 331, 339 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": 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DerHautarzt.70480817.eng.abstr
DerHautarzt.70480817.eng.abstr
[ { "id": "DerHautarzt.70480817.eng.abstr-passage-0", "type": "abstract", "text": [ "We surgically treated twenty patients with axillary hyperhidrosis by liposuction using tumescent regional anesthesia . After a description of the surgical technique results are presented . Except for trivial hematomas , no complications were seen . Every patient noted a significant reduction of sweat gland activity in the follow up period . Long-term results remain to be seen ." ], "offsets": [ [ 0, 380 ] ] } ]
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[]
[]
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DerHautarzt.70480828.eng.abstr
DerHautarzt.70480828.eng.abstr
[ { "id": "DerHautarzt.70480828.eng.abstr-passage-0", "type": "abstract", "text": [ "A 54-year old , obese woman suffered from massive symmetrical swelling of the face , especially of the upper and lower eyelids . Initially the swelling occured intermittently , but after 2 years it was permanent and progressive markedly limiting her visual fields . Neither laboratory findings nor imaging procedures provided any firm evidence of an underlying cardiac , renal or endocrinological disease . There was no suggestion of a storage disease . Skin biopsy showed foam cells and granulomatous inflammation , so the patient was tentatively diagnosed as having a monosymptomatic Melkersson-Rosenthal Syndrome . Eyelid surgery was performed to improve her visual fields . Treatment with clofazimine 100 mg daily was initiated . Regular follow-up visits over 7 months revealed no evidence of recurrence . The patient died a sudden cardiac death a few months later . The relatives refused an autopsy . The definite cause of her facial swelling remains unclear as we discuss the differential diagnostic possibilities ." ], "offsets": [ [ 0, 1021 ] ] } ]
[ { "id": "DerHautarzt.70480828.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "old" ], "offsets": [ [ 10, 13 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0331059" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "obese" ], "offsets": [ [ 16, 21 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0028754" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "woman" ], "offsets": [ [ 22, 27 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043210" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "face" ], "offsets": [ [ 78, 82 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015450" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "eyelids" ], "offsets": [ [ 119, 126 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015426" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "visual fields" ], "offsets": [ [ 250, 263 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042826" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "laboratory" ], "offsets": [ [ 274, 284 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022877" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "findings" ], "offsets": [ [ 285, 293 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243095" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "imaging" ], "offsets": [ [ 298, 305 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011923" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "procedures" ], "offsets": [ [ 306, 316 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0184661" }, { "db_name": "UMLS", "db_id": "C0025664" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 397, 404 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "imaging procedures" ], "offsets": [ [ 298, 316 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011923" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "suggestion" ], "offsets": [ [ 420, 430 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038659" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 444, 451 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "Skin" ], "offsets": [ [ 454, 458 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "biopsy" ], "offsets": [ [ 459, 465 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220797" }, { "db_name": "UMLS", "db_id": "C0005558" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 478, 483 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "inflammation" ], "offsets": [ [ 502, 514 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021368" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 524, 531 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s5-t6", "type": "umlsterm", "text": [ "Syndrome" ], "offsets": [ [ 607, 615 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039082" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s5-t7", "type": "umlsterm", "text": [ "foam cells" ], "offsets": [ [ 473, 483 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016390" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s5-t8", "type": "umlsterm", "text": [ "Melkersson-Rosenthal Syndrome" ], "offsets": [ [ 586, 615 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025235" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "Eyelid" ], "offsets": [ [ 618, 624 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015426" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "surgery" ], "offsets": [ [ 625, 632 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "visual fields" ], "offsets": [ [ 662, 675 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042826" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "Treatment" ], "offsets": [ [ 678, 687 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "clofazimine" ], "offsets": [ [ 693, 704 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0008996" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "recurrence" ], "offsets": [ [ 797, 807 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034897" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s9-t1", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 814, 821 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s9-t2", "type": "umlsterm", "text": [ "death" ], "offsets": [ [ 844, 849 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011065" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s9-t3", "type": "umlsterm", "text": [ "patient died" ], "offsets": [ [ 814, 826 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011065" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s9-t4", "type": "umlsterm", "text": [ "cardiac death" ], "offsets": [ [ 836, 849 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376297" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s9-t5", "type": "umlsterm", "text": [ "sudden cardiac death" ], "offsets": [ [ 829, 849 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0085298" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s10-t1", "type": "umlsterm", "text": [ "relatives" ], "offsets": [ [ 875, 884 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0080103" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s10-t2", "type": "umlsterm", "text": [ "autopsy" ], "offsets": [ [ 896, 903 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004398" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s11-t1", "type": "umlsterm", "text": [ "cause" ], "offsets": [ [ 919, 924 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015127" } ] }, { "id": "DerHautarzt.70480828.eng.abstr-s11-t2", "type": "umlsterm", "text": [ "diagnostic" ], "offsets": [ [ 995, 1005 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0348026" } ] } ]
[]
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"DerHautarzt.70480828.eng.abstr-s9-r13-t2.1-t3.1", "type": "evaluation_of", "arg1_id": "DerHautarzt.70480828.eng.abstr-s11-t2", "arg2_id": "DerHautarzt.70480828.eng.abstr-s9-t3", "normalized": [] } ]
DerHautarzt.70480834.eng.abstr
DerHautarzt.70480834.eng.abstr
[ { "id": "DerHautarzt.70480834.eng.abstr-passage-0", "type": "abstract", "text": [ "Paraneoplastic markers in tumor patients may occur at various stages of the disease . While some disorders almost invariably herald an underlying malignancy ( obligative marker ) , most only occasionally do so ( facultative marker ) . The association of bullous pemphigoid with malignancy is controversial . There are only a few reports of bullous pemphigoid associated with a renal cell carcinoma . We diagnosed a renal cell carcinoma in a 74 year old female patient , admitted to the hospital because of bullous pemphigoid . Multiple metastases were found in her lymph nodes , liver , lung and skeleton . The patient died eleven weeks after the first symptoms of bullous pemphigoid appeared ." ], "offsets": [ [ 0, 694 ] ] } ]
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], "offsets": [ [ 97, 106 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "malignancy" ], "offsets": [ [ 146, 156 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006826" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "marker" ], "offsets": [ [ 170, 176 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005516" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "marker" ], "offsets": [ [ 224, 230 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0005516" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "association" ], "offsets": [ [ 239, 250 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004083" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "pemphigoid" ], "offsets": [ [ 262, 272 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030805" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "malignancy" ], "offsets": [ [ 278, 288 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006826" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "bullous pemphigoid" ], "offsets": [ [ 254, 272 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030805" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "pemphigoid" ], "offsets": [ [ 348, 358 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030805" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 383, 387 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "carcinoma" ], "offsets": [ [ 388, 397 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "bullous pemphigoid" ], "offsets": [ [ 340, 358 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030805" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "renal cell carcinoma" ], "offsets": [ [ 377, 397 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007134" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 421, 425 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "carcinoma" ], "offsets": [ [ 426, 435 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007097" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "old" ], "offsets": [ [ 449, 452 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0331059" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "female" ], "offsets": [ [ 453, 459 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0086287" }, { "db_name": "UMLS", "db_id": "C0015780" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 460, 467 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s5-t6", "type": "umlsterm", "text": [ "hospital" ], "offsets": [ [ 486, 494 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019994" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s5-t7", "type": "umlsterm", "text": [ "pemphigoid" ], "offsets": [ [ 514, 524 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030805" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s5-t8", "type": "umlsterm", "text": [ "bullous pemphigoid" ], "offsets": [ [ 506, 524 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030805" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s5-t9", "type": "umlsterm", "text": [ "renal cell carcinoma" ], "offsets": [ [ 415, 435 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007134" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "metastases" ], "offsets": [ [ 536, 546 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027627" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "lymph" ], "offsets": [ [ 565, 570 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024202" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s6-t3", "type": "umlsterm", "text": [ "liver" ], "offsets": [ [ 579, 584 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0345904" }, { "db_name": "UMLS", "db_id": "C0023884" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s6-t4", "type": "umlsterm", "text": [ "lung" ], "offsets": [ [ 587, 591 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024109" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s6-t5", "type": "umlsterm", "text": [ "skeleton" ], "offsets": [ [ 596, 604 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037253" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s6-t6", "type": "umlsterm", "text": [ "lymph nodes" ], "offsets": [ [ 565, 576 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024204" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 611, 618 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "symptoms" ], "offsets": [ [ 653, 661 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0683368" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s7-t3", "type": "umlsterm", "text": [ "pemphigoid" ], "offsets": [ [ 673, 683 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030805" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s7-t4", "type": "umlsterm", "text": [ "patient died" ], "offsets": [ [ 611, 623 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011065" } ] }, { "id": "DerHautarzt.70480834.eng.abstr-s7-t5", "type": "umlsterm", "text": [ "bullous pemphigoid" ], "offsets": [ [ 665, 683 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030805" } ] } ]
[]
[]
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DerHautarzt.70480877.eng.abstr
DerHautarzt.70480877.eng.abstr
[ { "id": "DerHautarzt.70480877.eng.abstr-passage-0", "type": "abstract", "text": [ "Recently , Rebora et al reported on painful sensations of the scalp occurring in 34.2% of two hundred and twenty-two of their female patients seeking advice for hair loss , and proposed the term trichodynia for it . In the absence of any relationship with other parameters of hair loss and any histopathological data , they did not offer any explanation for such a symptom , but speculated on the possible role of inflammation , in as much as in androgenetic alopecia a perifollicular infiltrate has been described and credited of pathogenetic importance . On the other hand , many such individuals are classified as suffering of dysmorphic delusions , chronic tactile hallucinosis , obsessive worries , or depres- sion . Newer findings demonstrating localization of the neuropeptide substance P ( SP ) in the scalp skin of such patients suggest a causal role of SP , wich is known to be involved in neurogenic inflammation and nociception . The role of SP and related substances ( neuropeptides ) in the pathogenesis of trichodynia , and the relation of such substances to the psyche and emotional stress ( psychoneuroendocrinimmunology ) need further elucidation . For the time being , it is important to realize , that a clinical diagnosis of \" trichodynia \" is not the final diagnosis , but only a starting point in reaching a conclusive interpretation of the symptom with its implications for treatment and prognosis ." ], "offsets": [ [ 0, 1423 ] ] } ]
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DerHautarzt.70480881.eng.abstr
DerHautarzt.70480881.eng.abstr
[ { "id": "DerHautarzt.70480881.eng.abstr-passage-0", "type": "abstract", "text": [ "Introduced in 1979 , isotretinoin remains a major advance in acne therapy . Both hospital- and community-based dermatologists have experience with this valuable drug , which , owing to its causal principle of action , offers a large proportion of patients the prospect of a cure . Isotretinoin is now in use in more than 80 countries and has been prescribed for some six million patients . Based on accumulated clinical findings with the drug , more comprehensive recommendations can now be made with respect to indications , dosing and duration of treatment than was possible when the drug was launched . Experience with the drug also provides a basis for reevaluating its safety profile . Finally , at a time when healthcare resources are limited , it is important to examine the cost-benefit ratio of this acne treatment versus other options . This paper is accordingly intended to provide a critical status report as well as a detailed and balanced set of recommendations for clinical practice ." ], "offsets": [ [ 0, 999 ] ] } ]
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[]
[]
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DerHautarzt.70480886.eng.abstr
DerHautarzt.70480886.eng.abstr
[ { "id": "DerHautarzt.70480886.eng.abstr-passage-0", "type": "abstract", "text": [ "By varying the light spectrum , impulse length , impulse sequences and fluences , the PhotoDermVL allows a large choice of individual treatment parameters . Superficial as well as deeper localized vascular malformations ( essential telangiectases , port-wine stains , Poikiloderma of Civatte , hemangiomatous malformations ) and cosmetically bothering hypertrichosis can be treated successfully with this high intensity polychromatic pulsed light source ." ], "offsets": [ [ 0, 455 ] ] } ]
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[]
[]
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DerHautarzt.70480894.eng.abstr
DerHautarzt.70480894.eng.abstr
[ { "id": "DerHautarzt.70480894.eng.abstr-passage-0", "type": "abstract", "text": [ "Seven patients with pulmonary metastases of malignant melanoma were treated with inhalation therapy with 36 million IU interleukin-2 for six months . Inhalation therapy was combined with four bolus infusions of DTIC at a dose of 850 mg/m2 once every four weeks . Response rates were 71,4% with 2 patients achieving a complete remission ( CR ) , 2 partial remissions ( PR ) , 1 stable disease ( SD ) , and 2 progressing disease ( PD ) . Therapy was well tolerated with low toxicity . Six of the patients developed cough ; one patient was slightly feverish . We conclude that inhalation therapy of lung metastases is a promising addition to the therapeutic arsenal against malignant melanoma ." ], "offsets": [ [ 0, 691 ] ] } ]
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[]
[]
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DerHautarzt.70480897.eng.abstr
DerHautarzt.70480897.eng.abstr
[ { "id": "DerHautarzt.70480897.eng.abstr-passage-0", "type": "abstract", "text": [ "Chronic venous insufficiency ( CVI ) is characterised by stage-dependent microangiopathy . With increasing severity there is a decrease in the number of skin capillaries and the oxygen partial pressure . The cutaneous vascular reserve , which is measured by laser-doppler fluxmetry , is reduced . Cutaneous microangiopathy is one of the main causes of the trophic disturbances associated with CVI . Low frequency pulsed current improves cutaneous microcirculation and thus nutrition as well as accelerating the formation of granulation tissue . In a open prospective pilot study , 15 patients suffering from CVI with persistent leg ulcers were treated with low frequency pulsed current ( Dermapulse ) , which is thought to improve particularly the tissue microcirculation . The average age of the patients was 70.3 years and the average duration of ulceration was 79.1 months . The patients were treated over a period of 38 days . With this treatmen , 2 ulcers healed completely and 13 showed a reduction of size of on average 63% . Capillary density increased by 43.5% , while transcutaneous oxygen partial pressure increased by 82.4% . Electrostimulation is a treatment with few or no side effects ." ], "offsets": [ [ 0, 1201 ] ] } ]
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[]
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DerHautarzt.70480904.eng.abstr
DerHautarzt.70480904.eng.abstr
[ { "id": "DerHautarzt.70480904.eng.abstr-passage-0", "type": "abstract", "text": [ "17% of malignant melanomas ( n=100) investigated in a dermatologic practice were less than 6 mm in maximal diameter ( median diameter : 4.0 +/- 0.9 mm ) . The median age of the 17 patients at diagnosis of small-diameter melanomas was 42 years . The essential epiluminescence microscopic and histopatologic features of these small melanomas resembled those of larger lesions , although their clinical criteria differed from the classic ABCDs . 6 ( 35,3% ) of the small melanomas were were found to be in situ . This percentage was nearly similar to those in situ lesions within the group of melanomas of 6 mm in diameter or larger ( 38,3% ) . The remaining 11 small lesions were classified as invasive from Clark's level I to V , including all classic histogenetic types ( superficial spreading , nodular , unclassified , desmoplastic ) . The median thickness of the small invasive melanomas was 0,76 +/- 0,23 mm . 7 small melanomas had apparent histologic remnants of a melanocytic nevus . Epiluminescence microscopic features of the melanomas were evaluated and statistically compared with those of 100 dysplastic nevi and 50 spindle cell nevi . The technique of epiluminescence microscopy allowed the identification of such malignant melanomas that could not be discerned by the naked eye or by a pocket-lens ." ], "offsets": [ [ 0, 1312 ] ] } ]
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[]
[]
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DerHautarzt.70480910.eng.abstr
DerHautarzt.70480910.eng.abstr
[ { "id": "DerHautarzt.70480910.eng.abstr-passage-0", "type": "abstract", "text": [ "Three patients with biopsy-proven bullous pemphigoid ( BP ) and anti-basement-membrane antibodies were treated weekly with low-dose methotrexate ( MTX ) 12,5-25 mg . To accelerate recovery we initially combined MTX with systemic and/or topical corticosteroids . In combination with MTX , the initial dose of 32 mg corticosteroids/day was sufficient . In all 3 patients the BP disappeared within 4 weeks . To maintain this beneficial effect , very low doses of MTX ( 25 mg every other week or every four weeks ) suffered . Opportunistic infections did not appear . Laboratory tests during MTX-treatment revealed no immunosuppression . The treatment was well tolerated ; we could neither observe subjective problems nor other pathologic changes . There are several lines of evidence for immunomodulating effects of MTX and the clinical benefit in BP might be possibly due to these actions of MTX . Our data show , that the treatment of BP with low-dose MTX is an effective alternative with a favorable benefit/side-effect ratio ." ], "offsets": [ [ 0, 1027 ] ] } ]
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[]
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DerHautarzt.70480923.eng.abstr
DerHautarzt.70480923.eng.abstr
[ { "id": "DerHautarzt.70480923.eng.abstr-passage-0", "type": "abstract", "text": [ "Elastosis perforans serpiginosa can arise as a rare complication in patients with Down syndrome . It is one of the primary perforating disorders characterized by transepithelial elimination of abnormal elastic fibers . This may reflect an immunological reaction aquist elastic fibers . We describe a 40-year-old woman with Down's syndrome whose skin lesions were histologically mistaken for lupus vulgaris for a long time ." ], "offsets": [ [ 0, 423 ] ] } ]
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[]
[]
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DerHautarzt.70480926.eng.abstr
DerHautarzt.70480926.eng.abstr
[ { "id": "DerHautarzt.70480926.eng.abstr-passage-0", "type": "abstract", "text": [ "A 52 year old female had a large destructive basal cell carcinoma of the back measuring 27 cm in diameter . There was destruction of the vertebral bodies , envelopment of the medullary cone , early spinal compression and soft tissue spread into the retroperitoneum . Early neurological defects were present . The tumor was excised , covered with two large rotation flaps and post operatively irradiated . The patients quality of life has improved , the tumor has not progressed and there is no sign of paraplegia ." ], "offsets": [ [ 0, 514 ] ] } ]
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[]
[]
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"normalized": [] } ]
DerHautarzt.70480929.eng.abstr
DerHautarzt.70480929.eng.abstr
[ { "id": "DerHautarzt.70480929.eng.abstr-passage-0", "type": "abstract", "text": [ "Anti-semitism increased from year to year in Nazi Germany from 1933 to 1945. The fear of annihilation resulted in a surge of suicides . The suicides of at least 9 Jewish dermatologists has been documented . Their mean age was 65 years . Couples often committed suicide together . At the end of World War II , the head of the dermatological department of the Prague University committed suicide . We assume the same happened in Rostock and Dresden . The president of the German Dermatological Society ( DDG ) committed suicide on March 27 , 1945. The motives of these dermatologists were obviously the collapse of Nazism and the fear of relatiatory measures ." ], "offsets": [ [ 0, 658 ] ] } ]
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[]
[]
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DerHautarzt.80490002.eng.abstr
DerHautarzt.80490002.eng.abstr
[ { "id": "DerHautarzt.80490002.eng.abstr-passage-0", "type": "abstract", "text": [ "The weeping fig , Ficus benjamina ( Fb ) , is a relatively common indoor allergen . Many cases of perennial allergic rhinoconjunctivitis and allergic asthma caused by Fb hypersensitivity are not detected . These patients typically have proven sensitization to housedust mites and do not improve after avoidance of exposure ( encasing ) and specific immunotherapy . The number of Fb sensitizations is increasing in Germany , which can partly be explained by the cross-reactivity between Hevea brasiliensis ( Hb ) latex and Fb and the rapidly increasing number of mostly occupational latex allergies . But Fb itself is a potential sensitizer which is widely spread as ornamental plant in homes and offices . As relevant indoor allergen Fb ranks third after housedust mites and pets but before molds among our allergy patients . For diagnosis , prick-tests with Fb-latex seem to be more sensitive than in vitro-methods ( RAST , CAP-RAST ) . Fb plants should not be kept in the homes of atopic individuals or persons with latex ( Hb ) allergy ." ], "offsets": [ [ 0, 1040 ] ] } ]
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[]
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DerHautarzt.80490006.eng.abstr
DerHautarzt.80490006.eng.abstr
[ { "id": "DerHautarzt.80490006.eng.abstr-passage-0", "type": "abstract", "text": [ "The effects of glycerol are discussed in detail . Glycerol can lead to a transition of crystalline lipid structures within the horny layer lipids into liquid crystalline states . Especially if applied in oil/water-emulsions it improves , the hydration of the horny layers better than urea . In addition , if facilitates the dissolution of desmosomes within the superior layers of the horny layer enhancing desquamation . Furthermore , by using glycerol , the mechanical properties of the skin can be influenced ; long term used leads to increased elasticity . The roughness of the horny layer is reduced , which can be explained by the abrasive and/or the hydrating effect . Glycerol used in o/w-emulsions also protects against the influence of tensides or noxious lipophilic agents . Presumably a flux from the base of the epidermis towards its surface triggers the regeneration of the barrier . Finally , glycerol can lead - similarly to urea - to an improvement in active agent penetration , as has been proven for hexylnicotinate ." ], "offsets": [ [ 0, 1035 ] ] } ]
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[]
[]
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DerHautarzt.80490010.eng.abstr
DerHautarzt.80490010.eng.abstr
[ { "id": "DerHautarzt.80490010.eng.abstr-passage-0", "type": "abstract", "text": [ "A rising incidence worldwide of skin cancer has been observed for years . A high cumulative exposure to UV radiation is a major factor in the development of such neoplasms . Suitable protective measures are therefore becoming increasingly important . Textiles provide simple , effective and medically safe protection against UV radiation . At present , however , in Europe - in contrat to Australia - the UV protection factor ( UPF ) for summer textiles is not stated . It is a largely unknown fact that by far not all textiles offer sufficient protection . Our goal was to study the factors which determine the UV transmission of fabrics and , based on these findings , to design materials which provide enhanced protection . A spectrophotometric method was used to determine the UV transmission by fabrics made of cotton , silk , polyester and viscose . The UV protection factors of the fabrics were computed on the basis of the transmission data . The UV protection factor is dependent on the type of fibre , yarn and surface design , weight per square metre , moisture content , colour , finishing method and degree of wear . To optimize the UV protection via textiles , a viscose yarn with a low UV transmission was used . This yarn makes it possible to design light-weight summer fabrics with optimized UV protection . This development will make it possible to offer clothing with high UV protection on the European marked . This clothing will not be more expensive than normal products , so that effective prevention should be more available ." ], "offsets": [ [ 0, 1550 ] ] } ]
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[]
[]
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DerHautarzt.80490017.eng.abstr
DerHautarzt.80490017.eng.abstr
[ { "id": "DerHautarzt.80490017.eng.abstr-passage-0", "type": "abstract", "text": [ "We describe an immunochemotherapy for metastatic melanoma that combines epifocal applications of the contact sensitizer DNCB over cutaneous metastases with systemic DTIC treatment . 4 complete remissions and 3 partial remissions were achieved in 15 patients . 6 of these remissions were seen in the 7 previously untreated patients . The advantages of this therapy which is in particular interesting for dermatologists are tolerable side effects and low costs . This publication is designed to stimulate larger randomized trials in order to answer open questions ." ], "offsets": [ [ 0, 563 ] ] } ]
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[]
[]
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DerHautarzt.80490023.eng.abstr
DerHautarzt.80490023.eng.abstr
[ { "id": "DerHautarzt.80490023.eng.abstr-passage-0", "type": "abstract", "text": [ "Disseminated Langerhans-cell-histiocytosis ( LCH ) is most frequent in children at the age of 1-3 years , seldomly seen in adults and extremely rare in the elderly . The clinical course may be acute , subacute or chronic , progressive or stationary . Spontaneous remissions are possible , but rare . In elderly patients often the disease is at first limited to the skin before it becomes systemic ." ], "offsets": [ [ 0, 398 ] ] } ]
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[]
[]
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DerHautarzt.80490036.eng.abstr
DerHautarzt.80490036.eng.abstr
[ { "id": "DerHautarzt.80490036.eng.abstr-passage-0", "type": "abstract", "text": [ "A 48 year old women developed granulomatous slack skin ( GSS ) , one of the special forms of cutaneous T-cell lymphoma . The lesional skin slack with an atrophic , poikilodermic surface and granulomatous induration . Histopathological findings included epidermotropism , diffuse lymphoid cell infiltration and foreign body giant cells as well as granulomatous reactions from superficial to deep dermis , including part the subcutis . The diagnosis was established by positive results for rearrangement of the T-cell receptor gene . The therapeutic possibilities , especially with corticosteroides and monitoring the disease course by following serum angiotensin converting enzyme activity are discussed ." ], "offsets": [ [ 0, 704 ] ] } ]
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"offsets": [ [ 110, 118 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024299" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "T-cell lymphoma" ], "offsets": [ [ 103, 118 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079772" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "granulomatous slack skin" ], "offsets": [ [ 30, 54 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376407" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "cutaneous T-cell lymphoma" ], "offsets": [ [ 93, 118 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0079773" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 134, 138 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "Histopathological" ], "offsets": [ [ 217, 234 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243140" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "findings" ], "offsets": [ [ 235, 243 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243095" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "cell" ], "offsets": [ [ 288, 292 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "giant" ], "offsets": [ [ 323, 328 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017547" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "cells" ], "offsets": [ [ 329, 334 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007634" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "dermis" ], "offsets": [ [ 395, 401 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011646" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s3-t7", "type": "umlsterm", "text": [ "lymphoid cell" ], "offsets": [ [ 279, 292 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0086574" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s3-t8", "type": "umlsterm", "text": [ "foreign body" ], "offsets": [ [ 310, 322 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016542" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s3-t9", "type": "umlsterm", "text": [ "giant cells" ], "offsets": [ [ 323, 334 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017526" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 438, 447 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "T-cell" ], "offsets": [ [ 509, 515 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039194" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "gene" ], "offsets": [ [ 525, 529 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0017337" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "therapeutic" ], "offsets": [ [ 536, 547 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039796" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 616, 623 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "angiotensin" ], "offsets": [ [ 650, 661 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003018" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "enzyme" ], "offsets": [ [ 673, 679 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0014442" }, { "db_name": "UMLS", "db_id": "C0014445" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "disease course" ], "offsets": [ [ 616, 630 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0242656" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s5-t6", "type": "umlsterm", "text": [ "enzyme activity" ], "offsets": [ [ 673, 688 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243102" } ] }, { "id": "DerHautarzt.80490036.eng.abstr-s5-t7", "type": "umlsterm", "text": [ "angiotensin converting enzyme" ], "offsets": [ [ 650, 679 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0022709" } ] } ]
[]
[]
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DerHautarzt.80490048.eng.abstr
DerHautarzt.80490048.eng.abstr
[ { "id": "DerHautarzt.80490048.eng.abstr-passage-0", "type": "abstract", "text": [ "Scleredema adultorum of Buschke is a rare disorder of unknown aetiology . It is characterized by diffuse , non-pitting swelling and induration of the skin . Skin biopsies reveal marked thickening of the dermis due to collagenous replacement of the subcutis and deposition of hyaluronic acid between the collagen fibers . The disease classically only affects the skin . In 24 cases an associated monoclonal gammopathy has been detected ." ], "offsets": [ [ 0, 436 ] ] } ]
[ { "id": "DerHautarzt.80490048.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Scleredema" ], "offsets": [ [ 0, 10 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036413" } ] }, { "id": "DerHautarzt.80490048.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "disorder" ], "offsets": [ [ 42, 50 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerHautarzt.80490048.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "aetiology" ], "offsets": [ [ 62, 71 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0007463" } ] }, { "id": "DerHautarzt.80490048.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 150, 154 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.80490048.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "Skin" ], "offsets": [ [ 157, 161 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.80490048.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "biopsies" ], "offsets": [ [ 162, 170 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220797" }, { "db_name": "UMLS", "db_id": "C0005558" } ] }, { "id": "DerHautarzt.80490048.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "dermis" ], "offsets": [ [ 203, 209 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011646" } ] }, { "id": "DerHautarzt.80490048.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "acid" ], "offsets": [ [ 286, 290 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001128" } ] }, { "id": "DerHautarzt.80490048.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "collagen" ], "offsets": [ [ 303, 311 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009325" } ] }, { "id": "DerHautarzt.80490048.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "hyaluronic acid" ], "offsets": [ [ 275, 290 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020196" } ] }, { "id": "DerHautarzt.80490048.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 325, 332 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerHautarzt.80490048.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 362, 366 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.80490048.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "monoclonal gammopathy" ], "offsets": [ [ 395, 416 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030489" } ] } ]
[]
[]
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DerHautarzt.80490056.eng.abstr
DerHautarzt.80490056.eng.abstr
[ { "id": "DerHautarzt.80490056.eng.abstr-passage-0", "type": "abstract", "text": [ "The colour black often has a negative symbolic connotation . However , our synopsis of its occurrence in dermatology , and the historical changes and sociocultural differences in the way it is viewed , highlight the diversity of its potential meaning . Unlike any other colour , black requires personal confrontation ." ], "offsets": [ [ 0, 318 ] ] } ]
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[]
[]
[]
DerHautarzt.80490087.eng.abstr
DerHautarzt.80490087.eng.abstr
[ { "id": "DerHautarzt.80490087.eng.abstr-passage-0", "type": "abstract", "text": [ "Based on its unique botulinum toxin is referred to as the most poisonous poison . Its specific inhibition of the acetyl-cholin-dependent neuromuscular transmission is used by ophthalmologists and neurologists for the relaxation of spastic or dystonic muscles , preferrably in muscle groups in the head and neck area . Analogously , it is being used by dermatologists to remove facial wrinkles by paralyzing mimic muscles which account for mechanically induced wrinkling . Apart from this purely cosmetic use , botulinum toxin has gained recent attention in dermatology as a potent treatment modality for circumscribed hyperhidrosis ." ], "offsets": [ [ 0, 633 ] ] } ]
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[]
[]
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DerHautarzt.80490091.eng.abstr
DerHautarzt.80490091.eng.abstr
[ { "id": "DerHautarzt.80490091.eng.abstr-passage-0", "type": "abstract", "text": [ "The gene of the cyclin-dependent kinase 4 ( CDK4)-inhibitor p16INK4A ( CDKN2/MTS1) has been proposed as a candidate for a tumor-suppressor gene located on chromosome 9p21, a frequently deleted region in a series of human cancers including malignant melanoma . An increasing and sometimes conflicting body of data has accumulated regarding the frequency of homozygous deletions and mutations as well as the importance of p16INK4A in malignant melanoma . The purpose of this review is therefore to summarize the current knowledge on p16INK4A and to discuss its biologic significance in the pathogenesis of melanocytic tumors ." ], "offsets": [ [ 0, 624 ] ] } ]
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[]
[]
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DerHautarzt.80490101.eng.abstr
DerHautarzt.80490101.eng.abstr
[ { "id": "DerHautarzt.80490101.eng.abstr-passage-0", "type": "abstract", "text": [ "Severe hyperhidrosis may present as a vexing condition for the patient and a therapeutic challenge for the physician . As botulinum toxin-A ( BT-A ) can potently block cholinergic sympathic innervation of sweat glands it was used in an open trial for controlling severe axillary hyperhidrosis . After visualization of hyperhidrosis using the iodine-starch-test BT-A ( Dysport , 400 Units ) was injected intradermally in one axilla . One week later gravimetric quantification of sweat secretion revealed a reduction of sweating to 4-9% of initial values . In order to rule out daily variations as well as other factors interfering with sweat production BT-A treatment was restricted to only one axilla in each individual clearly demonstrating extensive anhidrotic efficacy on the treated side only . The treatment was well tolerated without side-effects and was assessed as ' completely satisfying ' by all patients . BT-A may offer a fast , safe and highly effective therapeutic option for severe hyperhi-drosis ." ], "offsets": [ [ 0, 1013 ] ] } ]
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], "offsets": [ [ 205, 217 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038989" } ] }, { "id": "DerHautarzt.80490101.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "visualization" ], "offsets": [ [ 301, 314 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0150627" } ] }, { "id": "DerHautarzt.80490101.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "hyperhidrosis" ], "offsets": [ [ 318, 331 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0020458" } ] }, { "id": "DerHautarzt.80490101.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "hyperhidrosis" ], "offsets": [ [ 318, 331 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038990" } ] }, { "id": "DerHautarzt.80490101.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "axilla" ], "offsets": [ [ 424, 430 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004454" } ] }, { "id": "DerHautarzt.80490101.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "sweat" ], "offsets": [ [ 478, 483 ] ], "normalized": [ { "db_name": 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"offsets": [ [ 635, 640 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038990" }, { "db_name": "UMLS", "db_id": "C0038984" } ] }, { "id": "DerHautarzt.80490101.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "production" ], "offsets": [ [ 641, 651 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033268" } ] }, { "id": "DerHautarzt.80490101.eng.abstr-s5-t4", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 657, 666 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerHautarzt.80490101.eng.abstr-s5-t5", "type": "umlsterm", "text": [ "axilla" ], "offsets": [ [ 694, 700 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004454" } ] }, { "id": "DerHautarzt.80490101.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 803, 812 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": 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[]
[]
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DerHautarzt.80490104.eng.abstr
DerHautarzt.80490104.eng.abstr
[ { "id": "DerHautarzt.80490104.eng.abstr-passage-0", "type": "abstract", "text": [ "The desmoplastic type of the squamous cell carcinoma ( DSCC ) of the skin is an entity which is readily distinguished by light microscopy . The DSCC has fine branches surrounded by a desmoplastic stroma and shows in some cases typical perineural , perivascular and widespread intradermal invasion ( maximum 6 cm ! ) . This type accounts for 8.2% ( n=44) of our collective of 594 squamous cell carcinomas ( SCC ) of the skin and vermilion border . Clinically DSCC look like other malignant epithelial tumors of the skin . All tumors were followed up for at least 3 years ( maximum 10 years ) . The local recurrence rate was high ( 24.3% ) even though micrographic surgery was carried out . The rate of local or regional metastasis was also very high ( 22.7% ) . In comparison the recurrence rate and the rate of metatasis of the remaining common 91.8% SCC's ( n=550) was low : 2.6% and 3.8% , respectively . The DSCC seems to be identical with the so called neurotropic SCC , the fine stranded SCC or the SCC with perineural invasion which have a high rate of local recurrence and metastasis as well , but DSCC is a better generic histopathologic term for the entire group . The DSCC is best treated with micrographic surgery and wider safety margins than any other type and should be followed up very frequently ." ], "offsets": [ [ 0, 1313 ] ] } ]
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[]
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DerHautarzt.80490109.eng.abstr
DerHautarzt.80490109.eng.abstr
[ { "id": "DerHautarzt.80490109.eng.abstr-passage-0", "type": "abstract", "text": [ "Hyperhidrosis is due to an overfunction of eccrine glands ( triggered by the autonomous nervous system ) and may be a cofactor for palmoplantar eczema ( dermatitis ) . Tapwater iontophoresis was used in 54 patients with hyperhidrosis manuum et pedum . After 10 applications directed by the dermatologist , 89% of patients noted an improvement in their hyperhidrosis . 20 patients suffering from palmoplantar eczema ( dermatitis ) who continued the treatment at home for at least 6 months were compared with a historical sex- and age-matched group of 20 eczema-patients without iontophoresis : The factors evaluated were the time needed for clearing and the relapse-free interval . Though iontophoresis-treated patients had a slightly faster clearing , this was statistically not significant ( 20 vs. 22.3 days ; p > 0.05 ) . However , the difference for relapse-free interval between the two groups was statistically highly significant ( 24.8 weeks vs. 8.35 weeks ; p 0.0001 ) . Tapwater iontophoresis seems to be effective not only to control sweating . According to recently published data , galvanization seems to have a capsaicin-like effect as well . Our hypothesis is therefore , that galvanization with tapwater iontophoresis interrupts the neurogenic inflammation and prolongs the relapse-free interval in hyperhidrotic palmoplantar eczema ( dermatitis ) ." ], "offsets": [ [ 0, 1364 ] ] } ]
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[]
[]
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DerHautarzt.80490123.eng.abstr
DerHautarzt.80490123.eng.abstr
[ { "id": "DerHautarzt.80490123.eng.abstr-passage-0", "type": "abstract", "text": [ "A 11-year-old girl suffering from grand mal epilepsy underwent antiepileptic therapy with carbamazepine ( 600 mg/daily ) . Two weeks after increasing the dose ( 900 mg/day ) she suddenly developed relatively sharply limited , sunburn-like brown reddish macular lesions with central scaling and partly hyperkeratotic areas on the hands , feet , face , knees , gluteal and axillar regions . Otherwise no health disorders were found ; in particular no neurological or gastrointestinal symptoms occurred . After reduction of the dosis ( 450 mg/day ) these skin lesions faded away . With exception of elevated serum levels of carbamazepine , nicotinamide and vitamin B6, all blood tests were in normal range . Interactions of carbamazepine with the vitamin B6- nicotinamide metabolism are the reason for these previously undescribed cutaneous side effects in connection with carbamazepine therapy . The present case demonstrates a toxic , non-allergic reaction during carbamazepine treatment with pellagroid skin symptoms ." ], "offsets": [ [ 0, 1018 ] ] } ]
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[]
[]
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DerHautarzt.80490126.eng.abstr
DerHautarzt.80490126.eng.abstr
[ { "id": "DerHautarzt.80490126.eng.abstr-passage-0", "type": "abstract", "text": [ "Although drug eruptions resembling graft-versus-host disease are rare , GvH-like reactions to the sulfhydryl group of drugs ( penicillamine , captopril , gold sodium ) , phenobarbital and hepatitis vaccine have been described . Clinical reports concerning acute GvH-like drug rash are very uncommon and restricted to acetylsalicylic acid and spironolactone . We report on a patient who developed an acute GvH-like drug reaction caused by allopurinol . To our knowledge this variant of cytotoxic drug eruption has not yet been reported in literature ." ], "offsets": [ [ 0, 550 ] ] } ]
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"captopril" ], "offsets": [ [ 142, 151 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0006938" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "gold" ], "offsets": [ [ 154, 158 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018026" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "sodium" ], "offsets": [ [ 159, 165 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037473" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "phenobarbital" ], "offsets": [ [ 170, 183 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031412" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s1-t10", "type": "umlsterm", "text": [ "hepatitis" ], "offsets": [ [ 188, 197 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019158" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s1-t11", "type": "umlsterm", "text": [ "vaccine" ], "offsets": [ [ 198, 205 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042210" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s1-t12", "type": "umlsterm", "text": [ "drug eruptions" ], "offsets": [ [ 9, 23 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011609" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s1-t13", "type": "umlsterm", "text": [ "graft-versus-host disease" ], "offsets": [ [ 35, 60 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018133" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s1-t14", "type": "umlsterm", "text": [ "sulfhydryl group" ], "offsets": [ [ 98, 114 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038734" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s1-t15", "type": "umlsterm", "text": [ "hepatitis vaccine" ], "offsets": [ [ 188, 205 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0042723" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "drug" ], "offsets": [ [ 271, 275 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013227" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "rash" ], "offsets": [ [ 276, 280 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015230" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "acid" ], "offsets": [ [ 333, 337 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001128" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "spironolactone" ], "offsets": [ [ 342, 356 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037982" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "drug rash" ], "offsets": [ [ 271, 280 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011609" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s2-t6", "type": "umlsterm", "text": [ "acetylsalicylic acid" ], "offsets": [ [ 317, 337 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0004057" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 374, 381 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "drug" ], "offsets": [ [ 414, 418 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013227" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "allopurinol" ], "offsets": [ [ 438, 449 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002144" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "knowledge" ], "offsets": [ [ 459, 468 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376554" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "drug" ], "offsets": [ [ 495, 499 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013227" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "literature" ], "offsets": [ [ 538, 548 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023866" } ] }, { "id": "DerHautarzt.80490126.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "drug eruption" ], "offsets": [ [ 495, 508 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011609" } ] } ]
[]
[]
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DerHautarzt.80490135.eng.abstr
DerHautarzt.80490135.eng.abstr
[ { "id": "DerHautarzt.80490135.eng.abstr-passage-0", "type": "abstract", "text": [ "Lichen aureus is a special localized variant of purpura pigmentosa chronica . A patient presented with an unusual striate and segmental or zosteriform distribution of lichen aureus involving the left leg and lower abdominal area . Histology showed the characteristic dense band-like infiltrate consisting mainly of small lymphocytes and numerous hemosiderin-containing macrophages . No underlying infection or medication could be identified as a trigger . The lesions did not respond well to topical corticosteroid therapy ." ], "offsets": [ [ 0, 524 ] ] } ]
[ { "id": "DerHautarzt.80490135.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "Lichen" ], "offsets": [ [ 0, 6 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023657" } ] }, { "id": "DerHautarzt.80490135.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "purpura" ], "offsets": [ [ 48, 55 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0034150" } ] }, { "id": "DerHautarzt.80490135.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 80, 87 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.80490135.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "distribution" ], "offsets": [ [ 151, 163 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0520511" } ] }, { "id": "DerHautarzt.80490135.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "lichen" ], "offsets": [ [ 167, 173 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023657" } ] }, { "id": "DerHautarzt.80490135.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "leg" ], "offsets": [ [ 200, 203 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023216" } ] }, { "id": "DerHautarzt.80490135.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "Histology" ], "offsets": [ [ 231, 240 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019638" }, { "db_name": "UMLS", "db_id": "C0205462" } ] }, { "id": "DerHautarzt.80490135.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "lymphocytes" ], "offsets": [ [ 321, 332 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024264" } ] }, { "id": "DerHautarzt.80490135.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "macrophages" ], "offsets": [ [ 369, 380 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024432" } ] }, { "id": "DerHautarzt.80490135.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "infection" ], "offsets": [ [ 397, 406 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0021311" } ] }, { "id": "DerHautarzt.80490135.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "medication" ], "offsets": [ [ 410, 420 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013227" } ] }, { "id": "DerHautarzt.80490135.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "corticosteroid" ], "offsets": [ [ 500, 514 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001617" } ] }, { "id": "DerHautarzt.80490135.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 515, 522 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] } ]
[]
[]
[ { "id": "DerHautarzt.80490135.eng.abstr-s1-r1-t2.1-t1.1", "type": "affects", "arg1_id": "DerHautarzt.80490135.eng.abstr-s5-t2", "arg2_id": "DerHautarzt.80490135.eng.abstr-s5-t1", "normalized": [] }, { "id": "DerHautarzt.80490135.eng.abstr-s3-r1-t3.1-t1.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490135.eng.abstr-s3-t3", "arg2_id": "DerHautarzt.80490135.eng.abstr-s5-t1", "normalized": [] }, { "id": "DerHautarzt.80490135.eng.abstr-s3-r2-t1.2-t1.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490135.eng.abstr-s3-t1", "arg2_id": "DerHautarzt.80490135.eng.abstr-s5-t1", "normalized": [] }, { "id": "DerHautarzt.80490135.eng.abstr-s4-r1-t2.1-t1.1", "type": "diagnoses", "arg1_id": "DerHautarzt.80490135.eng.abstr-s5-t2", "arg2_id": "DerHautarzt.80490135.eng.abstr-s5-t1", "normalized": [] } ]
DerHautarzt.80490139.eng.abstr
DerHautarzt.80490139.eng.abstr
[ { "id": "DerHautarzt.80490139.eng.abstr-passage-0", "type": "abstract", "text": [ "The dermatology clinic in Krefeld has treated a wide range of patients since its founding in 1845. Nowadays the spectrum consists of allergology , occupational dermatology , phototherapy , dermatosurgery , phlebology and proctology as well as special clinics for andrology , sexually transmitted diseases and patients with HIV-infection ." ], "offsets": [ [ 0, 338 ] ] } ]
[ { "id": "DerHautarzt.80490139.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "dermatology" ], "offsets": [ [ 4, 15 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011627" } ] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 62, 70 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "dermatology" ], "offsets": [ [ 160, 171 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011627" } ] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "phototherapy" ], "offsets": [ [ 174, 186 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031765" } ] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "dermatosurgery" ], "offsets": [ [ 189, 203 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0038894" }, { "db_name": "UMLS", "db_id": "C0038895" } ] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "proctology" ], "offsets": [ [ 221, 231 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0033248" } ] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "andrology" ], "offsets": [ [ 263, 272 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0085806" } ] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "diseases" ], "offsets": [ [ 296, 304 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 309, 317 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-t10", "type": "umlsterm", "text": [ "sexually transmitted diseases" ], "offsets": [ [ 275, 304 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036916" } ] } ]
[]
[]
[ { "id": "DerHautarzt.80490139.eng.abstr-s1-r1-t10.1-t9.1", "type": "occurs_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t10", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t9", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r2-t5.2-t6.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t5", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r3-t9.1-t4.1", "type": "performs", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t9", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r4-t9.1-t7.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t9", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r5-t10.1-t5.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t10", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r6-t2.1-t4.1", "type": "performs", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t2", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r7-t2.1-t7.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t2", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r9-t9.1-t6.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t9", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r10-t4.1-t3.1", "type": "method_of", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t4", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r11-t5.2-t2.1", "type": "occurs_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t5", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r12-t5.2-t4.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t5", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r13-t2.1-t6.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t2", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r14-t4.1-t9.1", "type": "affects", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t4", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t9", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r15-t10.1-t2.1", "type": "occurs_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t10", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r16-t9.1-t5.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t9", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r17-t10.1-t3.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t10", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r18-t4.1-t6.1", "type": "method_of", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t4", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r19-t4.1-t2.1", "type": "affects", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t4", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r20-t10.1-t5.2", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t10", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r21-t2.1-t5.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t2", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r22-t5.2-t3.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t5", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r23-t4.1-t1.1", "type": "method_of", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t4", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r24-t4.1-t10.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t4", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t10", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r25-t10.1-t1.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t10", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r26-t9.1-t3.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t9", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r27-t9.1-t5.2", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t9", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r28-t5.2-t1.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t5", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r29-t2.1-t3.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t2", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t3", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r30-t4.1-t7.1", "type": "method_of", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t4", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r31-t2.1-t5.2", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t2", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r32-t10.1-t7.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t10", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r33-t4.1-t5.2", "type": "method_of", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t4", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r34-t4.1-t5.2", "type": "associated_with", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t4", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r35-t5.2-t7.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t5", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t7", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r36-t5.2-t9.1", "type": "occurs_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t5", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t9", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r37-t10.1-t4.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t10", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t4", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r38-t9.1-t1.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t9", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t1", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r39-t10.1-t6.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t10", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t6", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r40-t4.1-t5.1", "type": "method_of", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t4", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerHautarzt.80490139.eng.abstr-s1-r41-t2.1-t1.1", "type": "issue_in", "arg1_id": "DerHautarzt.80490139.eng.abstr-s1-t2", "arg2_id": "DerHautarzt.80490139.eng.abstr-s1-t1", "normalized": [] } ]
DerHautarzt.80490170.eng.abstr
DerHautarzt.80490170.eng.abstr
[ { "id": "DerHautarzt.80490170.eng.abstr-passage-0", "type": "abstract", "text": [ "Although the barrier function and thickness of the stratum corneum is fully developed in newborns , the infant shows numerous differences in cutaneous and systemic metabolism of topically applied substances in comparison to adults . This discrepancy between children and adults has been explained by the greater systemic availability due to the greater surface area to weight ratio in children . Several topically applied drugs such as hexachlorophene , phenol , salicylic acid and boric acid in high concentration or on large areas have caused toxic reactions and fatalities in infants . Therapeutic approaches to childhood dermatoses differ from these used in adults . These age-dependent differences concerning the topical application of glucocorticosteroids , urea and dyes are described for the treatment of atopic eczema . The development of innovative topical drugs may extend therapeutic options especially in children as shown by a new topical anesthetic cream improving the treatment of mollusca contagiosa , a common childhood problem . Finally , certain physiological differences should be considered in newborn and infant skin care ." ], "offsets": [ [ 0, 1146 ] ] } ]
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[]
[]
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DerHautarzt.80490176.eng.abstr
DerHautarzt.80490176.eng.abstr
[ { "id": "DerHautarzt.80490176.eng.abstr-passage-0", "type": "abstract", "text": [ "Recent in vitro-studies have substantially increased our knowledge of eosinophil activation , the regulation of eosinophilia in the peripheral blood and the role of cytokines in that process . Accordingly , chemoattraction and activation of eosinophils by cytokines results in the local release of reactive oxygen species and toxic cationic granule proteins followed by local propagation of the inflammatory reaction and tissue damage . This extracellular tissue deposition of toxic granule proteins as an expression of complete activation of eosinophils , rather than only the presence of intact eosinophil granulocytes , is crucial for their functional effect in situ . Semiquantitative studies of local eosinophil granula deposition so far have been done only in atopic dermatitis and a limited number of other inflammatory skin diseases as summarized in this review . Evaluation of the pathogenetic role of eosinophils may be of potential therapeutic importance ." ], "offsets": [ [ 0, 967 ] ] } ]
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DerHautarzt.80490184.eng.abstr
DerHautarzt.80490184.eng.abstr
[ { "id": "DerHautarzt.80490184.eng.abstr-passage-0", "type": "abstract", "text": [ "Through cooperation between the German Contact Dermatitis Research Group ( DKG ) and the Information Network of Departments of Dermatology ( IVDK ) , results of standardized patch tests performed by the participating centres are centrally recorded in Germany . For this study , data from 24 departments of dermatology ( 19678 patients ) were evaluated retrospectively and separately for 1995 and 1996. With decreasing frequency , nickel , fragrance mix , balsam of peru , and thimerosal yielded positive reactions most often ; suprisingly high numbers of positive reactions were also seen with amerchol L-101 and palladium . Differentiated lists of allergens were compiled for 1995 , referring to subgroups of patients ( defined by gender , age , localization of eczema , geographical region , occupation , sensitization ) and particular problems . In men , percentages of positive reactions were markedly lower for nickel , fragrance mix and balsam of peru than in women . Younger patients reacted more often to thimerosal and older ones to topical medical preparations . Medical allergens were also often positive in patients with leg eczema , whereas occupational allergens were found more frequently in patients with hand eczema . A comparison of positive reactions obtained in distinct geographical regions was problematic because of differences between test populations . The spectrum of allergens found in officeworkers was similar to that of the whole test population . Patients with positive reactions to nickel and fragrance mix had more positive reactions to unrelated allergens than the total test population . Sex- and age-adjusted frequencies of sensitization revealed a decrease in reactions to nickel and an increase in reactions to mercury allergens from 1995 to 1996. The clinical relevance of mercury reactions was often not apparent . Differentiated lists of allergens can be used to improve the quality of diagnostic and prophylactic procedures in allergic contact dermatitis ." ], "offsets": [ [ 0, 1998 ] ] } ]
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[]
[]
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DerHautarzt.80490197.eng.abstr
DerHautarzt.80490197.eng.abstr
[ { "id": "DerHautarzt.80490197.eng.abstr-passage-0", "type": "abstract", "text": [ "Between 1982 and 1995 , over 700 HIV-infected patients with different skin diseases were registered at the Department of Dermatology , Benjamin Franklin Medical Center , The Free University of Berlin . Thirty-six of them ( ~5% ) were diagnosed as having psoriasis . This is clearly a higher prevalence of psoriasis than in the general population ( 1-2% ) . If psoriasis lesions are not clinically seen before diagnosis of HIV infection , the disease will preferentially ( ~80% of these cases ) appear during the late stages of the infection ( CD4/CD8 ratio 0.4 ) . Six of the 36 patients with HIV-related psoriasis ( =16% ) were found to have severe disease , showing an exsudative clinical picture . In this paper we report in detail on two representative cases from this group of patients . Histological examination also revealed exsudative changes in HIV-infected patients with clinically moderate psoriasis . Immunohistochemically , HIV-related psoriasis showed a moderately decreased number of infiltrating T-cells , in contrast to psoriatic skin from non-infected patients . A marked difference was the reduced expression of the lymphocyte antigen OPD-4 in HIV-related psoriasis . Routine antipsoriatic treatment modalities in combination with systemic retinoids and phototherapy ( SUP/PUVA ) were successful in the treatment of severe exsudative psoriasis in HIV patients , but the course of the disease was prolonged and exacerbation was more frequent . HIV-related psoriasis was found not to influence the underlying HIV infection ." ], "offsets": [ [ 0, 1541 ] ] } ]
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[]
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DerHautarzt.80490203.eng.abstr
DerHautarzt.80490203.eng.abstr
[ { "id": "DerHautarzt.80490203.eng.abstr-passage-0", "type": "abstract", "text": [ "The effectiveness of concurrent psychotherapeutic treatment for various skin diseases can be regarded as sufficiently validated . Contributions on in-patient treatment concepts are rare , and there are up to now no reports on methods integrating psychotherapeutic treatment approaches . Our concept of a 4-week short-term psychotherapy - starting from a conflict hypothesis in the complaint intensifying , acute situation - includes the bimodal work on both understanding and practice oriented treatment focus . By means of 2 case studies with 1-year-follow-up, insight is given into the treatment approach from which effective factors of psychotherapeutic treatment were tentatively in with patients with skin diseases ." ], "offsets": [ [ 0, 721 ] ] } ]
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[]
[]
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DerHautarzt.80490209.eng.abstr
DerHautarzt.80490209.eng.abstr
[ { "id": "DerHautarzt.80490209.eng.abstr-passage-0", "type": "abstract", "text": [ "Sweating ( perspiratio sensibilis ) due to cholinergic sweat gland activity serves predominantly for thermoregulation and is triggered among others by physical stress . Individuals suffering from atopic eczema usually respond to sweating with generalized itching . Different sweat regulation in atopic patients and healthy controls under cholinergic stimulation and heat chamber provocation tests has already been examined in several studies . However , no clinical trial has yet been done on atopic sweat regulation during physical stress . Sex-specific sweat secretion rates have not been evaluated . In our trial we compared sweat amounts of male and female atopics ( 14 m , 10 f ) and healthy controls ( 14 m , 10 f ) during and after physical activity on a bicycle ergometer . We used a special sweat collector system reliable even at intensive body movement . The individual stress limit had been determined by previous endurance training with lactate level and heart rate measurement . We found a highly significant difference in maximum sweat amounts between atopics and controls . On average , healthy individuals ( of both sexes ) perspired nearly three times as much as atopic patients . Male controls perspired nearly twice as much as corresponding females . Among the atopics , sex-specific differences were found to be not statistically relevant ." ], "offsets": [ [ 0, 1361 ] ] } ]
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[]
[]
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DerHautarzt.80490219.eng.abstr
DerHautarzt.80490219.eng.abstr
[ { "id": "DerHautarzt.80490219.eng.abstr-passage-0", "type": "abstract", "text": [ "A common adverse effect of minocycline therapy is cutaneous pigmentation . We describe two patients who presented with hyperpigmentation caused by minocycline . One patient , aged 54 years , had taken minocycline due to lung silicosis for 3 years before black pigmentation of the face occurred . The other 49 year-old patient developed grey-black hyperpigmentation on both lower legs after a 6-month therapy with minocycline for folliculitis . This patient was treated with the Q-switched ruby laser and the pigmentation resolved in the treated area . The different clinical and histological forms of minocycline-induced hyperpigmentation are discussed ." ], "offsets": [ [ 0, 654 ] ] } ]
[ { "id": "DerHautarzt.80490219.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "minocycline" ], "offsets": [ [ 27, 38 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026187" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 39, 46 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "pigmentation" ], "offsets": [ [ 60, 72 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031911" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "adverse effect" ], "offsets": [ [ 9, 23 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001688" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 91, 99 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "hyperpigmentation" ], "offsets": [ [ 119, 136 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162834" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "minocycline" ], "offsets": [ [ 147, 158 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026187" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 165, 172 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "minocycline" ], "offsets": [ [ 201, 212 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026187" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "lung" ], "offsets": [ [ 220, 224 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024109" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "silicosis" ], "offsets": [ [ 225, 234 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037116" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "black" ], "offsets": [ [ 254, 259 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037162" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "pigmentation" ], "offsets": [ [ 260, 272 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031911" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s3-t7", "type": "umlsterm", "text": [ "face" ], "offsets": [ [ 280, 284 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015450" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 318, 325 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-t2", "type": "umlsterm", "text": [ "grey-black" ], "offsets": [ [ 336, 346 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037162" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-t3", "type": "umlsterm", "text": [ "hyperpigmentation" ], "offsets": [ [ 347, 364 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162834" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-t4", "type": "umlsterm", "text": [ "legs" ], "offsets": [ [ 379, 383 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023216" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-t5", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 400, 407 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-t6", "type": "umlsterm", "text": [ "minocycline" ], "offsets": [ [ 413, 424 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0026187" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-t7", "type": "umlsterm", "text": [ "folliculitis" ], "offsets": [ [ 429, 441 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0016436" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 449, 456 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s5-t2", "type": "umlsterm", "text": [ "laser" ], "offsets": [ [ 494, 499 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023089" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s5-t3", "type": "umlsterm", "text": [ "pigmentation" ], "offsets": [ [ 508, 520 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031911" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "forms" ], "offsets": [ [ 592, 597 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376315" } ] }, { "id": "DerHautarzt.80490219.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "hyperpigmentation" ], "offsets": [ [ 621, 638 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162834" } ] } ]
[]
[]
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"DerHautarzt.80490219.eng.abstr-s4-t4", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s3-r6-t3.1-t7.1", "type": "adjacent_to", "arg1_id": "DerHautarzt.80490219.eng.abstr-s5-t3", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t7", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s3-r7-t7.1-t4.1", "type": "location_of", "arg1_id": "DerHautarzt.80490219.eng.abstr-s4-t7", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t4", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s3-r8-t4.1-t6.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490219.eng.abstr-s4-t4", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t6", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s3-r9-t3.1-t5.1", "type": "part_of", "arg1_id": "DerHautarzt.80490219.eng.abstr-s5-t3", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t5", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s3-r10-t6.1-t5.1", "type": "property_of", "arg1_id": "DerHautarzt.80490219.eng.abstr-s4-t6", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t5", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s3-r11-t7.1-t3.1", "type": "adjacent_to", "arg1_id": "DerHautarzt.80490219.eng.abstr-s4-t7", "arg2_id": "DerHautarzt.80490219.eng.abstr-s5-t3", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s3-r12-t3.1-t4.1", "type": "location_of", "arg1_id": "DerHautarzt.80490219.eng.abstr-s5-t3", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t4", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s3-r13-t4.1-t5.1", "type": "affects", "arg1_id": "DerHautarzt.80490219.eng.abstr-s4-t4", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t5", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s3-r14-t3.1-t2.1", "type": "produces", "arg1_id": "DerHautarzt.80490219.eng.abstr-s5-t3", "arg2_id": "DerHautarzt.80490219.eng.abstr-s6-t2", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s3-r15-t2.1-t3.1", "type": "disrupts", 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"associated_with", "arg1_id": "DerHautarzt.80490219.eng.abstr-s4-t5", "arg2_id": "DerHautarzt.80490219.eng.abstr-s5-t3", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r6-t5.1-t7.1", "type": "affects", "arg1_id": "DerHautarzt.80490219.eng.abstr-s4-t5", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t7", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r7-t2.1-t3.1", "type": "causes", "arg1_id": "DerHautarzt.80490219.eng.abstr-s6-t2", "arg2_id": "DerHautarzt.80490219.eng.abstr-s5-t3", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r8-t3.1-t7.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490219.eng.abstr-s5-t3", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t7", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r9-t7.1-t3.1", "type": "degree_of", "arg1_id": "DerHautarzt.80490219.eng.abstr-s4-t7", "arg2_id": "DerHautarzt.80490219.eng.abstr-s5-t3", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r10-t3.1-t1.1", "type": "occurs_in", "arg1_id": "DerHautarzt.80490219.eng.abstr-s5-t3", "arg2_id": "DerHautarzt.80490219.eng.abstr-s6-t1", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r11-t3.1-t5.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490219.eng.abstr-s5-t3", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t5", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r12-t4.1-t7.1", "type": "location_of", "arg1_id": "DerHautarzt.80490219.eng.abstr-s4-t4", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t7", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r13-t5.1-t3.1", "type": "affects", "arg1_id": "DerHautarzt.80490219.eng.abstr-s4-t5", "arg2_id": "DerHautarzt.80490219.eng.abstr-s5-t3", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r14-t3.1-t7.1", "type": "degree_of", "arg1_id": "DerHautarzt.80490219.eng.abstr-s5-t3", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t7", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r15-t3.1-t2.1", "type": "affects", "arg1_id": "DerHautarzt.80490219.eng.abstr-s5-t3", "arg2_id": "DerHautarzt.80490219.eng.abstr-s6-t2", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r16-t5.1-t7.1", "type": "treats", "arg1_id": "DerHautarzt.80490219.eng.abstr-s4-t5", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t7", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r17-t1.1-t5.1", "type": "performs", "arg1_id": "DerHautarzt.80490219.eng.abstr-s6-t1", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t5", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r18-t7.1-t5.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490219.eng.abstr-s4-t7", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t5", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r19-t4.1-t5.1", "type": "location_of", "arg1_id": "DerHautarzt.80490219.eng.abstr-s4-t4", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t5", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r20-t5.1-t7.1", "type": "diagnoses", "arg1_id": "DerHautarzt.80490219.eng.abstr-s4-t5", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t7", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r21-t5.1-t3.1", "type": "diagnoses", "arg1_id": "DerHautarzt.80490219.eng.abstr-s4-t5", "arg2_id": "DerHautarzt.80490219.eng.abstr-s5-t3", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r22-t2.1-t7.1", "type": "causes", "arg1_id": "DerHautarzt.80490219.eng.abstr-s6-t2", "arg2_id": "DerHautarzt.80490219.eng.abstr-s4-t7", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r23-t7.1-t1.1", "type": "occurs_in", "arg1_id": "DerHautarzt.80490219.eng.abstr-s4-t7", "arg2_id": "DerHautarzt.80490219.eng.abstr-s6-t1", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s4-r24-t7.1-t3.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490219.eng.abstr-s4-t7", "arg2_id": "DerHautarzt.80490219.eng.abstr-s5-t3", "normalized": [] }, { "id": "DerHautarzt.80490219.eng.abstr-s5-r1-t1.1-t2.1", "type": "uses", "arg1_id": "DerHautarzt.80490219.eng.abstr-s6-t1", "arg2_id": "DerHautarzt.80490219.eng.abstr-s6-t2", "normalized": [] } ]
DerHautarzt.80490224.eng.abstr
DerHautarzt.80490224.eng.abstr
[ { "id": "DerHautarzt.80490224.eng.abstr-passage-0", "type": "abstract", "text": [ "A 63-year-old women developed livedo reticularis during treatment with amantadine . This reversible side effect of amantadine has been most often seen in women and is frequently associated with persistent ankle edema . We discuss the signs and symptoms , pathogenesis and treatment of amantadine-induced livedo reticularis ." ], "offsets": [ [ 0, 324 ] ] } ]
[ { "id": "DerHautarzt.80490224.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "women" ], "offsets": [ [ 14, 19 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043210" } ] }, { "id": "DerHautarzt.80490224.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 56, 65 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerHautarzt.80490224.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "amantadine" ], "offsets": [ [ 71, 81 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002403" } ] }, { "id": "DerHautarzt.80490224.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "livedo reticularis" ], "offsets": [ [ 30, 48 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0085642" } ] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "amantadine" ], "offsets": [ [ 115, 125 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0002403" } ] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "women" ], "offsets": [ [ 154, 159 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0043210" } ] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "ankle" ], "offsets": [ [ 205, 210 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0003086" } ] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "edema" ], "offsets": [ [ 211, 216 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0013604" } ] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "side effect" ], "offsets": [ [ 100, 111 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0001688" } ] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "signs" ], "offsets": [ [ 234, 239 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220912" } ] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "symptoms" ], "offsets": [ [ 244, 252 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0683368" } ] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "pathogenesis" ], "offsets": [ [ 255, 267 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0543483" } ] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "treatment" ], "offsets": [ [ 272, 281 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "livedo reticularis" ], "offsets": [ [ 304, 322 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0085642" } ] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "signs and symptoms" ], "offsets": [ [ 234, 252 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037088" } ] } ]
[]
[]
[ { "id": "DerHautarzt.80490224.eng.abstr-s1-r1-t2.1-t4.1", "type": "affects", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t2", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s1-r2-t4.1-t2.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t2", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s1-r3-t4.1-t1.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s1-r4-t2.1-t4.1", "type": "treats", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t2", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s1-r5-t1.1-t2.1", "type": "performs", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t1", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t2", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s1-r6-t2.1-t4.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t2", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s1-r7-t2.1-t4.1", "type": "diagnoses", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t2", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s1-r8-t1.1-t4.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t1", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-r1-t4.1-t2.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t2", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-r2-t1.1-t4.1", "type": "diagnoses", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t1", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-r3-t4.1-t5.1", "type": "result_of", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-r4-t2.1-t5.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t2", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-r5-t1.1-t5.1", "type": "treats", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t1", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-r6-t2.1-t4.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t2", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-r7-t5.1-t4.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-r8-t5.1-t2.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t2", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-r9-t5.1-t4.1", "type": "result_of", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-r10-t1.1-t5.1", "type": "affects", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t1", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-r11-t1.1-t5.1", "type": "causes", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t1", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-r12-t3.1-t5.1", "type": "location_of", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t3", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-r13-t1.1-t5.1", "type": "diagnoses", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t1", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-r14-t4.1-t5.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-r15-t3.1-t4.1", "type": "location_of", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t3", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s2-r16-t1.1-t4.1", "type": "affects", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t1", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-r1-t4.1-t1.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-r2-t1.1-t5.1", "type": "treats", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t1", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-r3-t1.1-t2.1", "type": "treats", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t1", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t2", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-r4-t5.1-t4.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-r5-t5.1-t2.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t2", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-r6-t4.1-t5.1", "type": "treats", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-r7-t4.1-t2.1", "type": "treats", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t2", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-r8-t5.1-t1.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-r9-t4.1-t1.1", "type": "treats", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t1", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-r10-t1.1-t5.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t1", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-r11-t4.1-t5.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t5", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-r12-t1.1-t4.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t1", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t4", "normalized": [] }, { "id": "DerHautarzt.80490224.eng.abstr-s3-r13-t1.1-t2.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490224.eng.abstr-s3-t1", "arg2_id": "DerHautarzt.80490224.eng.abstr-s3-t2", "normalized": [] } ]
DerHautarzt.80490228.eng.abstr
DerHautarzt.80490228.eng.abstr
[ { "id": "DerHautarzt.80490228.eng.abstr-passage-0", "type": "abstract", "text": [ "We describe granulomatosis disciformis Miescher in a 57-year old female patient with typical clinical manifestation : disc-shaped plaques with slight central sclerosis and lesions resembling necrobiosis lipoidica and granuloma anulare . Histology revealed an infiltrate mainly composed of macrophages and lymphocytes and small foci of necrobiotic collagen and of new collagen formation . We review the literature on granulomatosis disciformis and nosology , concluding - as do most authors - that granulomatosis disciformis is a characteristic variant within the spectrum of cutaneous noninfectious granulomatous disease lying in between generalized granuloma anulare and necrobiosis lipoidica ." ], "offsets": [ [ 0, 695 ] ] } ]
[ { "id": "DerHautarzt.80490228.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "granulomatosis" ], "offsets": [ [ 12, 26 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018188" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "granulomatosis" ], "offsets": [ [ 12, 26 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0751995" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "old" ], "offsets": [ [ 61, 64 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0331059" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "female" ], "offsets": [ [ 65, 71 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0086287" }, { "db_name": "UMLS", "db_id": "C0015780" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 72, 79 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "plaques" ], "offsets": [ [ 130, 137 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011389" }, { "db_name": "UMLS", "db_id": "C0333463" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s1-t7", "type": "umlsterm", "text": [ "sclerosis" ], "offsets": [ [ 158, 167 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0036429" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s1-t8", "type": "umlsterm", "text": [ "necrobiosis" ], "offsets": [ [ 191, 202 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162812" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s1-t9", "type": "umlsterm", "text": [ "granuloma" ], "offsets": [ [ 217, 226 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018188" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s1-t10", "type": "umlsterm", "text": [ "necrobiosis lipoidica" ], "offsets": [ [ 191, 212 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027538" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "Histology" ], "offsets": [ [ 237, 246 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0019638" }, { "db_name": "UMLS", "db_id": "C0205462" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "macrophages" ], "offsets": [ [ 289, 300 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024432" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "lymphocytes" ], "offsets": [ [ 305, 316 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024264" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "collagen" ], "offsets": [ [ 347, 355 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009325" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s2-t5", "type": "umlsterm", "text": [ "collagen" ], "offsets": [ [ 367, 375 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0009325" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "literature" ], "offsets": [ [ 402, 412 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023866" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "granulomatosis" ], "offsets": [ [ 416, 430 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018188" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "granulomatosis" ], "offsets": [ [ 416, 430 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0751995" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s3-t4", "type": "umlsterm", "text": [ "granulomatosis" ], "offsets": [ [ 497, 511 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018188" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s3-t5", "type": "umlsterm", "text": [ "granulomatosis" ], "offsets": [ [ 497, 511 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0751995" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s3-t6", "type": "umlsterm", "text": [ "disease" ], "offsets": [ [ 613, 620 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s3-t7", "type": "umlsterm", "text": [ "granuloma" ], "offsets": [ [ 650, 659 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018188" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s3-t8", "type": "umlsterm", "text": [ "necrobiosis" ], "offsets": [ [ 672, 683 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0162812" } ] }, { "id": "DerHautarzt.80490228.eng.abstr-s3-t9", "type": "umlsterm", "text": [ "necrobiosis lipoidica" ], "offsets": [ [ 672, 693 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027538" } ] } ]
[]
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DerHautarzt.80490263.eng.abstr
DerHautarzt.80490263.eng.abstr
[ { "id": "DerHautarzt.80490263.eng.abstr-passage-0", "type": "abstract", "text": [ "Between 1988 and 1994 more than 40 monographs dealing with dermatologically relevant drugs have been published in an official German government publication , the \" Bundesanzeiger \" . These monographs represent reviews compiled by independent dermatological and pharmaceutical authorities working together in an expert commission and most of their information has proved valid . Thus , knowledge of these official reviews could help physicians to decide about the use of many drugs . However , they are not well-known to doctors . With this brief summary we hope to make more physicians familiar with these important monographs published in the \" Bundesanzeiger \" ." ], "offsets": [ [ 0, 664 ] ] } ]
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[]
[]
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DerHautarzt.80490270.eng.abstr
DerHautarzt.80490270.eng.abstr
[ { "id": "DerHautarzt.80490270.eng.abstr-passage-0", "type": "abstract", "text": [ "Behavioral medicine is a newer approach in the management of various diseases . In the last years , special programs have been de-veloped for atopic dermatitis , psoriasis vulgaris and other chronic skin diseases . An increase in the patient's self-control could be achieved by optimizing the patient's skills in dealing with their skin disease . The article summarizes the principles and procedures of in-patient behavioral medicine , especially the strategies employed by dermatological training groups and psychotherapeutical groups to help the patient deal with their skin disorder ." ], "offsets": [ [ 0, 587 ] ] } ]
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DerHautarzt.80490280.eng.abstr
DerHautarzt.80490280.eng.abstr
[ { "id": "DerHautarzt.80490280.eng.abstr-passage-0", "type": "abstract", "text": [ "The development of hand eczema is a relatively commonly seem dermatosis in housewives . In 1986 we presented a first survey of potential contact dermatitis sources for a housewife . Now , we present an update in which we analyse the different contact sources in the household and grade them in comparison to the data of 1986. The results are based on the analysis of a large population of 2633 patients with the occupation \" housewife \" and the diagnosis \" eczema \" who have been seen in departments of dermatology belonging to the Information Network of Departments of Dermatology ( IVDK ) ." ], "offsets": [ [ 0, 592 ] ] } ]
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[]
[]
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DerHautarzt.80490291.eng.abstr
DerHautarzt.80490291.eng.abstr
[ { "id": "DerHautarzt.80490291.eng.abstr-passage-0", "type": "abstract", "text": [ "In a randomized study 30 patients with chronic stationary psoriasis were treated with 3 different topical schemes . Group 1 ( n=10) received monotherapy ( dithranol ( D ) twice a day , D/D ) , group 2 ( n=10) calcipotriol mornings/dithranol evenings ( calcipotriol ( C ) /dithranol ( D ) C/D ) and 3 ( mometasone ( M ) mornings/dithranol ( D ) evenings , M/D ) . During the therapy period of 4 weeks we documented the PASI-Score as well as infiltration , erythema and desquamation weekly . The M/D group revealed in the first week a significantly faster reduction of the PASI-score ( 5,3 ) than in the D/D group ( PASI 13,22 ) . The C/D group ( PASI 10,5 ) show a not significantly faster reduction . After 4 weeks of treatment and after a follow period of 6 weeks there were similar PASI-Scores in all groups . There were less side-effects in the M/D group than in the others . The beginning , more anti-psoriatic effectiveness was achieved by the mometasone/dithranol combination than the other schemes . In the long term , the effects were similar ." ], "offsets": [ [ 0, 1052 ] ] } ]
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[]
[]
[ { "id": "DerHautarzt.80490291.eng.abstr-s1-r1-t2.1-t1.1", "type": "occurs_in", "arg1_id": "DerHautarzt.80490291.eng.abstr-s6-t2", "arg2_id": "DerHautarzt.80490291.eng.abstr-s8-t1", "normalized": [] }, { "id": "DerHautarzt.80490291.eng.abstr-s2-r1-t1.1-t2.1", "type": "interacts_with", "arg1_id": "DerHautarzt.80490291.eng.abstr-s8-t1", "arg2_id": "DerHautarzt.80490291.eng.abstr-s6-t2", "normalized": [] }, { "id": "DerHautarzt.80490291.eng.abstr-s2-r2-t2.1-t1.1", "type": "interacts_with", "arg1_id": "DerHautarzt.80490291.eng.abstr-s6-t2", "arg2_id": "DerHautarzt.80490291.eng.abstr-s8-t1", "normalized": [] }, { "id": "DerHautarzt.80490291.eng.abstr-s3-r1-t1.1-t3.1", "type": "result_of", "arg1_id": "DerHautarzt.80490291.eng.abstr-s8-t1", "arg2_id": "DerHautarzt.80490291.eng.abstr-s3-t3", "normalized": [] }, { "id": "DerHautarzt.80490291.eng.abstr-s3-r2-t3.1-t1.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490291.eng.abstr-s3-t3", "arg2_id": "DerHautarzt.80490291.eng.abstr-s8-t1", "normalized": [] }, { "id": "DerHautarzt.80490291.eng.abstr-s3-r3-t1.1-t3.1", "type": "treats", "arg1_id": "DerHautarzt.80490291.eng.abstr-s8-t1", "arg2_id": "DerHautarzt.80490291.eng.abstr-s3-t3", "normalized": [] }, { "id": "DerHautarzt.80490291.eng.abstr-s3-r4-t1.1-t3.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490291.eng.abstr-s8-t1", "arg2_id": "DerHautarzt.80490291.eng.abstr-s3-t3", "normalized": [] }, { "id": "DerHautarzt.80490291.eng.abstr-s3-r5-t3.1-t1.1", "type": "evaluation_of", "arg1_id": "DerHautarzt.80490291.eng.abstr-s3-t3", "arg2_id": "DerHautarzt.80490291.eng.abstr-s8-t1", "normalized": [] }, { "id": "DerHautarzt.80490291.eng.abstr-s3-r6-t3.1-t1.1", "type": "result_of", "arg1_id": "DerHautarzt.80490291.eng.abstr-s3-t3", "arg2_id": "DerHautarzt.80490291.eng.abstr-s8-t1", "normalized": [] } ]
DerHautarzt.80490295.eng.abstr
DerHautarzt.80490295.eng.abstr
[ { "id": "DerHautarzt.80490295.eng.abstr-passage-0", "type": "abstract", "text": [ "The simultaneous occurrence of lupus erythematosus ( LE ) - and lichen ruber ( LP ) -like symptoms is called LE/LP-overlap syndrome ( LE/LP-OS ) . It is defined by concomitant clinical , histologic and immunhistologic features of both diseases . To date , 47 cases of this rare dermatosis have been reported with marked differences in the skin lesions : They are either of intermediate appearance between LE and LP ( type I=intermediate type ) , or show a co-existence of LE- and LP-specific lesions ( type II=polar type ) . To determine the frequency and characteristics of the LE/LP-OS we reviewed our LE-patients from 1984-1995 . 5 cases were diagnosed . The frequency of LE/LP-OS in our patients is higher than generally assumed . Due to its variable clinical , histological and immunhistological appearance and the lack of unequivocal pathognomonic signs , this overlap-dermatosis may be underdiagnosed . Since therapeutic consequences result from the diagnosis , criteria are suggested to faciliate the recognition of the LE/LP-OS ." ], "offsets": [ [ 0, 1038 ] ] } ]
[ { "id": "DerHautarzt.80490295.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "occurrence" ], "offsets": [ [ 17, 27 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243132" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "lupus" ], "offsets": [ [ 31, 36 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0024138" }, { "db_name": "UMLS", "db_id": "C0024131" }, { "db_name": "UMLS", "db_id": "C0024141" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "erythematosus" ], "offsets": [ [ 37, 50 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0041834" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "lichen" ], "offsets": [ [ 64, 70 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0023657" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "symptoms" ], "offsets": [ [ 90, 98 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0683368" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s1-t6", "type": "umlsterm", "text": [ "syndrome" ], "offsets": [ [ 123, 131 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039082" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "histologic" ], "offsets": [ [ 187, 197 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0205462" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "diseases" ], "offsets": [ [ 235, 243 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0012634" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "date" ], "offsets": [ [ 249, 253 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011008" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "dermatosis" ], "offsets": [ [ 278, 288 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037274" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "skin" ], "offsets": [ [ 339, 343 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0037267" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s4-t1", "type": "umlsterm", "text": [ "frequency" ], "offsets": [ [ 542, 551 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376249" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s6-t1", "type": "umlsterm", "text": [ "frequency" ], "offsets": [ [ 662, 671 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0376249" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s6-t2", "type": "umlsterm", "text": [ "patients" ], "offsets": [ [ 691, 699 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s7-t1", "type": "umlsterm", "text": [ "signs" ], "offsets": [ [ 854, 859 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0220912" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s7-t2", "type": "umlsterm", "text": [ "overlap-dermatosis" ], "offsets": [ [ 867, 885 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0751995" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s8-t1", "type": "umlsterm", "text": [ "therapeutic" ], "offsets": [ [ 916, 927 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0039796" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s8-t2", "type": "umlsterm", "text": [ "diagnosis" ], "offsets": [ [ 957, 966 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011900" }, { "db_name": "UMLS", "db_id": "C0348026" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s8-t3", "type": "umlsterm", "text": [ "criteria" ], "offsets": [ [ 969, 977 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0243161" } ] }, { "id": "DerHautarzt.80490295.eng.abstr-s8-t4", "type": "umlsterm", "text": [ "recognition" ], "offsets": [ [ 1009, 1020 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0524637" } ] } ]
[]
[]
[ { "id": "DerHautarzt.80490295.eng.abstr-s1-r1-t3.1-t2.2", "type": "associated_with", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t3", "arg2_id": "DerHautarzt.80490295.eng.abstr-s8-t2", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s1-r2-t5.1-t2.3", "type": "associated_with", "arg1_id": "DerHautarzt.80490295.eng.abstr-s1-t5", "arg2_id": "DerHautarzt.80490295.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s1-r3-t3.1-t4.1", "type": "affects", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t3", "arg2_id": "DerHautarzt.80490295.eng.abstr-s8-t4", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s1-r4-t3.1-t2.2", "type": "degree_of", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t3", "arg2_id": "DerHautarzt.80490295.eng.abstr-s8-t2", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s1-r5-t5.1-t2.2", "type": "associated_with", "arg1_id": "DerHautarzt.80490295.eng.abstr-s1-t5", "arg2_id": "DerHautarzt.80490295.eng.abstr-s8-t2", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s1-r6-t3.1-t1.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t3", "arg2_id": "DerHautarzt.80490295.eng.abstr-s8-t1", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s1-r7-t3.1-t5.1", "type": "degree_of", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t3", "arg2_id": "DerHautarzt.80490295.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s1-r8-t3.1-t1.1", "type": "degree_of", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t3", "arg2_id": "DerHautarzt.80490295.eng.abstr-s8-t1", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s1-r9-t5.1-t3.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490295.eng.abstr-s1-t5", "arg2_id": "DerHautarzt.80490295.eng.abstr-s8-t3", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s1-r10-t3.1-t2.3", "type": "degree_of", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t3", "arg2_id": "DerHautarzt.80490295.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s1-r11-t5.1-t1.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490295.eng.abstr-s1-t5", "arg2_id": "DerHautarzt.80490295.eng.abstr-s8-t1", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s1-r12-t3.1-t2.3", "type": "associated_with", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t3", "arg2_id": "DerHautarzt.80490295.eng.abstr-s1-t2", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s1-r13-t3.1-t5.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t3", "arg2_id": "DerHautarzt.80490295.eng.abstr-s1-t5", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s3-r1-t3.1-t1.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t3", "arg2_id": "DerHautarzt.80490295.eng.abstr-s8-t1", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s3-r2-t3.1-t1.1", "type": "location_of", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t3", "arg2_id": "DerHautarzt.80490295.eng.abstr-s8-t1", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s3-r3-t1.1-t3.1", "type": "associated_with", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t1", "arg2_id": "DerHautarzt.80490295.eng.abstr-s8-t3", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s8-r1-t1.1-t2.2", "type": "affects", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t1", "arg2_id": "DerHautarzt.80490295.eng.abstr-s8-t2", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s8-r3-t3.1-t2.1", "type": "evaluation_of", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t3", "arg2_id": "DerHautarzt.80490295.eng.abstr-s8-t2", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s8-r4-t2.1-t1.1", "type": "precedes", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t2", "arg2_id": "DerHautarzt.80490295.eng.abstr-s8-t1", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s8-r5-t2.2-t1.1", "type": "evaluation_of", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t2", "arg2_id": "DerHautarzt.80490295.eng.abstr-s8-t1", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s8-r6-t3.1-t2.2", "type": "result_of", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t3", "arg2_id": "DerHautarzt.80490295.eng.abstr-s8-t2", "normalized": [] }, { "id": "DerHautarzt.80490295.eng.abstr-s8-r7-t3.1-t1.1", "type": "evaluation_of", "arg1_id": "DerHautarzt.80490295.eng.abstr-s8-t3", "arg2_id": "DerHautarzt.80490295.eng.abstr-s8-t1", "normalized": [] } ]
DerHautarzt.80490303.eng.abstr
DerHautarzt.80490303.eng.abstr
[ { "id": "DerHautarzt.80490303.eng.abstr-passage-0", "type": "abstract", "text": [ "A 56-year-old female patient with generalized granuloma anulare was treated with bath-PUVA therapy with 8-methoxypsoralen . Her diabetes mellitus renal insufficiency excluded oral photochemotherapy . A series of 30 treatments resulted in complete disappearance of the lesions on the trunk and neck and significant improvement of those on the limbs . No side-effects were observed . Bath-PUVA therapy seems to have positive effects not only on epidermal , but also on dermal processes ." ], "offsets": [ [ 0, 485 ] ] } ]
[ { "id": "DerHautarzt.80490303.eng.abstr-s1-t1", "type": "umlsterm", "text": [ "female" ], "offsets": [ [ 14, 20 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0086287" }, { "db_name": "UMLS", "db_id": "C0015780" } ] }, { "id": "DerHautarzt.80490303.eng.abstr-s1-t2", "type": "umlsterm", "text": [ "patient" ], "offsets": [ [ 21, 28 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0030705" } ] }, { "id": "DerHautarzt.80490303.eng.abstr-s1-t3", "type": "umlsterm", "text": [ "granuloma" ], "offsets": [ [ 46, 55 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0018188" } ] }, { "id": "DerHautarzt.80490303.eng.abstr-s1-t4", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 91, 98 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerHautarzt.80490303.eng.abstr-s1-t5", "type": "umlsterm", "text": [ "8-methoxypsoralen" ], "offsets": [ [ 104, 121 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0025684" } ] }, { "id": "DerHautarzt.80490303.eng.abstr-s2-t1", "type": "umlsterm", "text": [ "diabetes" ], "offsets": [ [ 128, 136 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011847" }, { "db_name": "UMLS", "db_id": "C0011849" } ] }, { "id": "DerHautarzt.80490303.eng.abstr-s2-t2", "type": "umlsterm", "text": [ "photochemotherapy" ], "offsets": [ [ 180, 197 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0031740" } ] }, { "id": "DerHautarzt.80490303.eng.abstr-s2-t3", "type": "umlsterm", "text": [ "diabetes mellitus" ], "offsets": [ [ 128, 145 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0011849" } ] }, { "id": "DerHautarzt.80490303.eng.abstr-s2-t4", "type": "umlsterm", "text": [ "renal insufficiency" ], "offsets": [ [ 146, 165 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0035078" } ] }, { "id": "DerHautarzt.80490303.eng.abstr-s3-t1", "type": "umlsterm", "text": [ "treatments" ], "offsets": [ [ 215, 225 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] }, { "id": "DerHautarzt.80490303.eng.abstr-s3-t2", "type": "umlsterm", "text": [ "neck" ], "offsets": [ [ 293, 297 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0027530" } ] }, { "id": "DerHautarzt.80490303.eng.abstr-s3-t3", "type": "umlsterm", "text": [ "limbs" ], "offsets": [ [ 342, 347 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0015385" } ] }, { "id": "DerHautarzt.80490303.eng.abstr-s5-t1", "type": "umlsterm", "text": [ "therapy" ], "offsets": [ [ 392, 399 ] ], "normalized": [ { "db_name": "UMLS", "db_id": "C0087111" }, { "db_name": "UMLS", "db_id": "C0039798" } ] } ]
[]
[]
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